메뉴 건너뛰기




Volumn 3, Issue SEP, 2015, Pages

Analytics for metabolic engineering

Author keywords

High throughput screening; Metabolic engineering; Metabolomics; Microfluidics; Proteomics; RNA seq

Indexed keywords

ASSAYS; DECISION MAKING; DIGITAL STORAGE; METABOLISM; MICROFLUIDICS; MOLECULAR BIOLOGY; MOLECULES; PROTEINS;

EID: 85013745565     PISSN: None     EISSN: 22964185     Source Type: Journal    
DOI: 10.3389/fbioe.2015.00135     Document Type: Review
Times cited : (74)

References (113)
  • 1
    • 84887538796 scopus 로고    scopus 로고
    • DNA sequence analysis with droplet-based microfluidics
    • Abate, A. R., Hung, T., Sperling, R. A., Mary, P., Rotem, A., Agresti, J. J., et al. (2013). DNA sequence analysis with droplet-based microfluidics. Lab. Chip 13, 4864-4869. doi:10.1039/c3lc50905b
    • (2013) Lab. Chip , vol.13 , pp. 4864-4869
    • Abate, A.R.1    Hung, T.2    Sperling, R.A.3    Mary, P.4    Rotem, A.5    Agresti, J.J.6
  • 2
    • 77957329119 scopus 로고    scopus 로고
    • Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli
    • Ajikumar, P. K., Xiao, W. H., Tyo, K. E., Wang, Y., Simeon, F., Leonard, E., et al. (2010). Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli. Science 330, 70-74. doi:10.1126/science.1191652
    • (2010) Science , vol.330 , pp. 70-74
    • Ajikumar, P.K.1    Xiao, W.H.2    Tyo, K.E.3    Wang, Y.4    Simeon, F.5    Leonard, E.6
  • 3
    • 84921278263 scopus 로고    scopus 로고
    • Principal component analysis of proteomics (PCAP) as a tool to direct metabolic engineering
    • Alonso-Gutierrez, J., Kim, E. M., Batth, T. S., Cho, N., Hu, Q., Chan, L. J., et al. (2015). Principal component analysis of proteomics (PCAP) as a tool to direct metabolic engineering. Metab. Eng. 28, 123-133. doi:10.1016/j.ymben.2014.11.011
    • (2015) Metab. Eng , vol.28 , pp. 123-133
    • Alonso-Gutierrez, J.1    Kim, E.M.2    Batth, T.S.3    Cho, N.4    Hu, Q.5    Chan, L.J.6
  • 6
    • 84865542140 scopus 로고    scopus 로고
    • Comparison and applications of label-free absolute proteome quantification methods on Escherichia coli
    • Arike, L., Valgepea, K., Peil, L., Nahku, R., Adamberg, K., and Vilu, R. (2012). Comparison and applications of label-free absolute proteome quantification methods on Escherichia coli. J. Proteomics 75, 5437-5448. doi:10.1016/j.jprot.2012.06.020
    • (2012) J. Proteomics , vol.75 , pp. 5437-5448
    • Arike, L.1    Valgepea, K.2    Peil, L.3    Nahku, R.4    Adamberg, K.5    Vilu, R.6
  • 7
    • 38049001166 scopus 로고    scopus 로고
    • Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
    • Atsumi, S., Hanai, T., and Liao, J. C. (2008). Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature 451, 86-89. doi:10.1038/nature06450
    • (2008) Nature , vol.451 , pp. 86-89
    • Atsumi, S.1    Hanai, T.2    Liao, J.C.3
  • 8
    • 79952348850 scopus 로고    scopus 로고
    • A synthetic library of RNA control modules for predictable tuning of gene expression in yeast
    • Babiskin, A. H., and Smolke, C. D. (2011). A synthetic library of RNA control modules for predictable tuning of gene expression in yeast. Mol. Syst. Biol. 7, 471. doi:10.1038/msb.2011.4
    • (2011) Mol. Syst. Biol , vol.7 , pp. 471
    • Babiskin, A.H.1    Smolke, C.D.2
  • 9
    • 33746606019 scopus 로고    scopus 로고
    • Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry
    • Bajad, S. U., Lu, W., Kimball, E. H., Yuan, J., Peterson, C., and Rabinowitz, J. D. (2006). Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry. J. Chromatogr. A. 1125, 76-88. doi:10.1016/j.chroma.2006.05.019
    • (2006) J. Chromatogr. A , vol.1125 , pp. 76-88
    • Bajad, S.U.1    Lu, W.2    Kimball, E.H.3    Yuan, J.4    Peterson, C.5    Rabinowitz, J.D.6
  • 10
    • 84943766626 scopus 로고    scopus 로고
    • Droplet microfluidics in (bio)chemical analysis
    • Basova, E. Y., and Foret, F. (2015). Droplet microfluidics in (bio)chemical analysis. Analyst 140, 22-38. doi:10.1039/c4an01209g
    • (2015) Analyst , vol.140 , pp. 22-38
    • Basova, E.Y.1    Foret, F.2
  • 11
    • 84907866236 scopus 로고    scopus 로고
    • A targeted proteomics toolkit for high-throughput absolute quantification of Escherichia coli proteins
    • Batth, T. S., Singh, P., Ramakrishnan, V. R., Sousa, M. M., Chan, L. J., Tran, H. M., et al. (2014). A targeted proteomics toolkit for high-throughput absolute quantification of Escherichia coli proteins. Metab. Eng. 26C, 48-56. doi:10.1016/j.ymben.2014.08.004
    • (2014) Metab. Eng , vol.26C , pp. 48-56
    • Batth, T.S.1    Singh, P.2    Ramakrishnan, V.R.3    Sousa, M.M.4    Chan, L.J.5    Tran, H.M.6
  • 12
    • 84897671128 scopus 로고    scopus 로고
    • Identification and characterization of a galacturonic acid transporter from Neurospora crassa and its application for Saccharomyces cerevisiae fermentation processes
    • Benz, J. P., Protzko, R. J., Andrich, J. M., Bauer, S., Dueber, J. E., and Somerville, C. R. (2014). Identification and characterization of a galacturonic acid transporter from Neurospora crassa and its application for Saccharomyces cerevisiae fermentation processes. Biotechnol. Biofuels 7, 20. doi:10.1186/1754-6834-7-20
    • (2014) Biotechnol. Biofuels , vol.7 , pp. 20
    • Benz, J.P.1    Protzko, R.J.2    Andrich, J.M.3    Bauer, S.4    Dueber, J.E.5    Somerville, C.R.6
  • 13
    • 84861434998 scopus 로고    scopus 로고
    • A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level
    • Binder, S., Schendzielorz, G., Stabler, N., Krumbach, K., Hoffmann, K., Bott, M., et al. (2012). A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level. Genome Biol. 13, R40. doi:10.1186/gb-2012-13-5-r40
    • (2012) Genome Biol , vol.13
    • Binder, S.1    Schendzielorz, G.2    Stabler, N.3    Krumbach, K.4    Hoffmann, K.5    Bott, M.6
  • 14
    • 83555163791 scopus 로고    scopus 로고
    • Integrating computational methods to retrofit enzymes to synthetic pathways
    • Brunk, E., Neri, M., Tavernelli, I., Hatzimanikatis, V., and Rothlisberger, U. (2012). Integrating computational methods to retrofit enzymes to synthetic pathways. Biotechnol. Bioeng. 109, 572-582. doi:10.1002/bit.23334
    • (2012) Biotechnol. Bioeng , vol.109 , pp. 572-582
    • Brunk, E.1    Neri, M.2    Tavernelli, I.3    Hatzimanikatis, V.4    Rothlisberger, U.5
  • 15
    • 70349959824 scopus 로고    scopus 로고
    • A proteomics approach to discovering natural products and their biosynthetic pathways
    • Bumpus, S. B., Evans, B. S., Thomas, P. M., Ntai, I., and Kelleher, N. L. (2009). A proteomics approach to discovering natural products and their biosynthetic pathways. Nat. Biotechnol. 27, 951-956. doi:10.1038/nbt.1565
    • (2009) Nat. Biotechnol , vol.27 , pp. 951-956
    • Bumpus, S.B.1    Evans, B.S.2    Thomas, P.M.3    Ntai, I.4    Kelleher, N.L.5
  • 16
    • 84907350970 scopus 로고    scopus 로고
    • Generation of an atlas for commodity chemical production in Escherichia coli and a novel pathway prediction algorithm, GEM-Path
    • Campodonico, M. A., Andrews, B. A., Asenjo, J. A., Palsson, B. O., and Feist, A. M. (2014). Generation of an atlas for commodity chemical production in Escherichia coli and a novel pathway prediction algorithm, GEM-Path. Metab. Eng. 25, 140-158. doi:10.1016/j.ymben.2014.07.009
    • (2014) Metab. Eng , vol.25 , pp. 140-158
    • Campodonico, M.A.1    Andrews, B.A.2    Asenjo, J.A.3    Palsson, B.O.4    Feist, A.M.5
  • 17
    • 84899702032 scopus 로고    scopus 로고
    • Retropath: automated pipeline for embedded metabolic circuits
    • Carbonell, P., Parutto, P., Baudier, C., Junot, C., and Faulon, J. L. (2014a). Retropath: automated pipeline for embedded metabolic circuits. ACS. Synth. Biol. 3, 565-577. doi:10.1021/sb4001273
    • (2014) ACS. Synth. Biol , vol.3 , pp. 565-577
    • Carbonell, P.1    Parutto, P.2    Baudier, C.3    Junot, C.4    Faulon, J.L.5
  • 19
    • 84863322344 scopus 로고    scopus 로고
    • Contextualizing context for synthetic biology-identifying causes of failure of synthetic biological systems
    • Cardinale, S., and Arkin, A. P. (2012). Contextualizing context for synthetic biology-identifying causes of failure of synthetic biological systems. Biotechnol. J. 7, 856-866. doi:10.1002/biot.201200085
    • (2012) Biotechnol. J , vol.7 , pp. 856-866
    • Cardinale, S.1    Arkin, A.P.2
  • 20
    • 84455174703 scopus 로고    scopus 로고
    • Model-driven engineering of RNA devices to quantitatively program gene expression
    • Carothers, J. M., Goler, J. A., Juminaga, D., and Keasling, J. D. (2011). Model-driven engineering of RNA devices to quantitatively program gene expression. Science 334, 1716-1719. doi:10.1126/science.1212209
    • (2011) Science , vol.334 , pp. 1716-1719
    • Carothers, J.M.1    Goler, J.A.2    Juminaga, D.3    Keasling, J.D.4
  • 21
    • 84879681227 scopus 로고    scopus 로고
    • Characterization of 582 natural and synthetic terminators and quantification of their design constraints
    • Chen, Y. J., Liu, P., Nielsen, A. A., Brophy, J. A., Clancy, K., Peterson, T., et al. (2013). Characterization of 582 natural and synthetic terminators and quantification of their design constraints. Nat. Methods 10, 659-664. doi:10.1038/nmeth.2515
    • (2013) Nat. Methods , vol.10 , pp. 659-664
    • Chen, Y.J.1    Liu, P.2    Nielsen, A.A.3    Brophy, J.A.4    Clancy, K.5    Peterson, T.6
  • 22
    • 84886022252 scopus 로고    scopus 로고
    • Programming adaptive control to evolve increased metabolite production
    • Chou, H. H., and Keasling, J. D. (2013). Programming adaptive control to evolve increased metabolite production. Nat. Commun. 4, 2595. doi:10.1038/ncomms3595
    • (2013) Nat. Commun , vol.4 , pp. 2595
    • Chou, H.H.1    Keasling, J.D.2
  • 24
    • 79951565301 scopus 로고    scopus 로고
    • Design, construction and characterization of a set of insulated bacterial promoters
    • Davis, J. H., Rubin, A. J., and Sauer, R. T. (2011). Design, construction and characterization of a set of insulated bacterial promoters. Nucleic Acids Res. 39, 1131-1141. doi:10.1093/nar/gkq810
    • (2011) Nucleic Acids Res , vol.39 , pp. 1131-1141
    • Davis, J.H.1    Rubin, A.J.2    Sauer, R.T.3
  • 25
    • 77953642931 scopus 로고    scopus 로고
    • High-throughput metabolic engineering: advances in small-molecule screening and selection
    • Dietrich, J. A., Mckee, A. E., and Keasling, J. D. (2010). High-throughput metabolic engineering: advances in small-molecule screening and selection. Annu. Rev. Biochem. 79, 563-590. doi:10.1146/annurev-biochem-062608-095938
    • (2010) Annu. Rev. Biochem , vol.79 , pp. 563-590
    • Dietrich, J.A.1    Mckee, A.E.2    Keasling, J.D.3
  • 26
    • 84875515904 scopus 로고    scopus 로고
    • Transcription factor-based screens and synthetic selections for microbial small-molecule biosynthesis
    • Dietrich, J. A., Shis, D. L., Alikhani, A., and Keasling, J. D. (2013). Transcription factor-based screens and synthetic selections for microbial small-molecule biosynthesis. ACS Synth. Biol. 2, 47-58. doi:10.1021/sb300091d
    • (2013) ACS Synth. Biol , vol.2 , pp. 47-58
    • Dietrich, J.A.1    Shis, D.L.2    Alikhani, A.3    Keasling, J.D.4
  • 27
    • 33750360806 scopus 로고    scopus 로고
    • Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry
    • Dorrestein, P. C., Bumpus, S. B., Calderone, C. T., Garneau-Tsodikova, S., Aron, Z. D., Straight, P. D., et al. (2006). Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry. Biochemistry 45, 12756-12766. doi:10.1021/bi061169d
    • (2006) Biochemistry , vol.45 , pp. 12756-12766
    • Dorrestein, P.C.1    Bumpus, S.B.2    Calderone, C.T.3    Garneau-Tsodikova, S.4    Aron, Z.D.5    Straight, P.D.6
  • 28
  • 29
    • 0141757323 scopus 로고    scopus 로고
    • Reprogramming control of an allosteric signaling switch through modular recombination
    • Dueber, J. E., Yeh, B. J., Chak, K., and Lim, W. A. (2003). Reprogramming control of an allosteric signaling switch through modular recombination. Science 301, 1904-1908. doi:10.1126/science.1085945
    • (2003) Science , vol.301 , pp. 1904-1908
    • Dueber, J.E.1    Yeh, B.J.2    Chak, K.3    Lim, W.A.4
  • 30
    • 84920889241 scopus 로고    scopus 로고
    • Novel screening methods-biosensors
    • Eggeling, L., Bott, M., and Marienhagen, J. (2015). Novel screening methods-biosensors. Curr. Opin. Biotechnol. 35C, 30-36. doi:10.1016/j.copbio.2014.12.021
    • (2015) Curr. Opin. Biotechnol , vol.35C , pp. 30-36
    • Eggeling, L.1    Bott, M.2    Marienhagen, J.3
  • 31
    • 45149111660 scopus 로고    scopus 로고
    • The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli
    • Feist, A. M., and Palsson, B. O. (2008). The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli. Nat. Biotechnol. 26, 659-667. doi:10.1038/nbt1401
    • (2008) Nat. Biotechnol , vol.26 , pp. 659-667
    • Feist, A.M.1    Palsson, B.O.2
  • 32
    • 84879830242 scopus 로고    scopus 로고
    • Investigating host dependence of xylose utilization in recombinant Saccharomyces cerevisiae strains using RNA-seq analysis
    • Feng, X., and Zhao, H. (2013). Investigating host dependence of xylose utilization in recombinant Saccharomyces cerevisiae strains using RNA-seq analysis. Biotechnol. Biofuels 6, 96. doi:10.1186/1754-6834-6-96
    • (2013) Biotechnol. Biofuels , vol.6 , pp. 96
    • Feng, X.1    Zhao, H.2
  • 33
    • 84903714435 scopus 로고    scopus 로고
    • Development of a native Escherichia coli induction system for ionic liquid tolerance
    • Frederix, M., Hutter, K., Leu, J., Batth, T. S., Turner, W. J., Ruegg, T. L., et al. (2014). Development of a native Escherichia coli induction system for ionic liquid tolerance. PLoS ONE 9, e101115. doi:10.1371/journal.pone.0101115
    • (2014) PLoS ONE , vol.9
    • Frederix, M.1    Hutter, K.2    Leu, J.3    Batth, T.S.4    Turner, W.J.5    Ruegg, T.L.6
  • 34
    • 80052785690 scopus 로고    scopus 로고
    • High-throughput, accurate mass metabolome profiling of cellular extracts by flow injection-time-of-flight mass spectrometry
    • Fuhrer, T., Heer, D., Begemann, B., and Zamboni, N. (2011). High-throughput, accurate mass metabolome profiling of cellular extracts by flow injection-time-of-flight mass spectrometry. Anal. Chem. 83, 7074-7080. doi:10.1021/ac201267k
    • (2011) Anal. Chem , vol.83 , pp. 7074-7080
    • Fuhrer, T.1    Heer, D.2    Begemann, B.3    Zamboni, N.4
  • 35
    • 84881061125 scopus 로고    scopus 로고
    • Recent advances in microfluidics combined with mass spectrometry: technologies and applications
    • Gao, D., Liu, H., Jiang, Y., and Lin, J. M. (2013). Recent advances in microfluidics combined with mass spectrometry: technologies and applications. Lab. Chip 13, 3309-3322. doi:10.1039/c3lc50449b
    • (2013) Lab. Chip , vol.13 , pp. 3309-3322
    • Gao, D.1    Liu, H.2    Jiang, Y.3    Lin, J.M.4
  • 36
    • 84899020457 scopus 로고    scopus 로고
    • On-chip spyhole mass spectrometry for droplet-based microfluidics
    • Gasilova, N., Yu, Q., Qiao, L., and Girault, H. H. (2014). On-chip spyhole mass spectrometry for droplet-based microfluidics. Angew. Chem. Int. Ed. Engl. 53, 4408-4412. doi:10.1002/anie.201310795
    • (2014) Angew. Chem. Int. Ed. Engl , vol.53 , pp. 4408-4412
    • Gasilova, N.1    Yu, Q.2    Qiao, L.3    Girault, H.H.4
  • 37
    • 84903144112 scopus 로고    scopus 로고
    • Correlation analysis of targeted proteins and metabolites to assess and engineer microbial isopentenol production
    • George, K. W., Chen, A., Jain, A., Batth, T. S., Baidoo, E. E., Wang, G., et al. (2014). Correlation analysis of targeted proteins and metabolites to assess and engineer microbial isopentenol production. Biotechnol. Bioeng. 111, 1648-1658. doi:10.1002/bit.25226
    • (2014) Biotechnol. Bioeng , vol.111 , pp. 1648-1658
    • George, K.W.1    Chen, A.2    Jain, A.3    Batth, T.S.4    Baidoo, E.E.5    Wang, G.6
  • 38
    • 84936890106 scopus 로고    scopus 로고
    • Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling
    • Ghaffari, P., Mardinoglu, A., Asplund, A., Shoaie, S., Kampf, C., Uhlen, M., et al. (2015). Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling. Sci. Rep. 5, 8183. doi:10.1038/srep08183
    • (2015) Sci. Rep , vol.5 , pp. 8183
    • Ghaffari, P.1    Mardinoglu, A.2    Asplund, A.3    Shoaie, S.4    Kampf, C.5    Uhlen, M.6
  • 39
    • 84861860481 scopus 로고    scopus 로고
    • Targeted data extraction of the MS/MS spectra generated by data-independent acquisition: a new concept for consistent and accurate proteome analysis
    • Gillet, L. C., Navarro, P., Tate, S., Rost, H., Selevsek, N., Reiter, L., et al. (2012). Targeted data extraction of the MS/MS spectra generated by data-independent acquisition: a new concept for consistent and accurate proteome analysis. Mol. Cell. Proteomics 11, O111016717. doi:10.1074/mcp.O111.016717
    • (2012) Mol. Cell. Proteomics , vol.11
    • Gillet, L.C.1    Navarro, P.2    Tate, S.3    Rost, H.4    Selevsek, N.5    Reiter, L.6
  • 40
    • 77954701087 scopus 로고    scopus 로고
    • Genome-scale metabolic model integrated with RNAseq data to identify metabolic states of Clostridium thermocellum
    • Gowen, C. M., and Fong, S. S. (2010). Genome-scale metabolic model integrated with RNAseq data to identify metabolic states of Clostridium thermocellum. Biotechnol. J. 5, 759-767. doi:10.1002/biot.201000084
    • (2010) Biotechnol. J , vol.5 , pp. 759-767
    • Gowen, C.M.1    Fong, S.S.2
  • 41
    • 84907459445 scopus 로고    scopus 로고
    • In vitro analysis of carboxyacyl substrate tolerance in the loading and first extension modules of borrelidin polyketide synthase
    • Hagen, A., Poust, S., De Rond, T., Yuzawa, S., Katz, L., Adams, P. D., et al. (2014). In vitro analysis of carboxyacyl substrate tolerance in the loading and first extension modules of borrelidin polyketide synthase. Biochemistry 53, 5975-5977. doi:10.1021/bi500951c
    • (2014) Biochemistry , vol.53 , pp. 5975-5977
    • Hagen, A.1    Poust, S.2    De Rond, T.3    Yuzawa, S.4    Katz, L.5    Adams, P.D.6
  • 43
    • 83255164998 scopus 로고    scopus 로고
    • Cell-free synthetic biology: thinking outside the cell
    • Hodgman, C. E., and Jewett, M. C. (2012). Cell-free synthetic biology: thinking outside the cell. Metab. Eng. 14, 261-269. doi:10.1016/j.ymben.2011.09.002
    • (2012) Metab. Eng , vol.14 , pp. 261-269
    • Hodgman, C.E.1    Jewett, M.C.2
  • 44
    • 62549134121 scopus 로고    scopus 로고
    • Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
    • Ingolia, N. T., Ghaemmaghami, S., Newman, J. R., and Weissman, J. S. (2009). Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science 324, 218-223. doi:10.1126/science.1168978
    • (2009) Science , vol.324 , pp. 218-223
    • Ingolia, N.T.1    Ghaemmaghami, S.2    Newman, J.R.3    Weissman, J.S.4
  • 45
    • 84894408697 scopus 로고    scopus 로고
    • Optimization of enzyme parameters for fermentative production of biorenewable fuels and chemicals
    • Jarboe, L. R., Liu, P., Kautharapu, K. B., and Ingram, L. O. (2012). Optimization of enzyme parameters for fermentative production of biorenewable fuels and chemicals. Comput. Struct. Biotechnol. J. 3, e201210005. doi:10.5936/csbj.201210005
    • (2012) Comput. Struct. Biotechnol. J , vol.3
    • Jarboe, L.R.1    Liu, P.2    Kautharapu, K.B.3    Ingram, L.O.4
  • 47
    • 53949093950 scopus 로고    scopus 로고
    • An integrated cell-free metabolic platform for protein production and synthetic biology
    • Jewett, M. C., Calhoun, K. A., Voloshin, A., Wuu, J. J., and Swartz, J. R. (2008). An integrated cell-free metabolic platform for protein production and synthetic biology. Mol. Syst. Biol. 4, 220. doi:10.1038/msb.2008.57
    • (2008) Mol. Syst. Biol , vol.4 , pp. 220
    • Jewett, M.C.1    Calhoun, K.A.2    Voloshin, A.3    Wuu, J.J.4    Swartz, J.R.5
  • 48
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
    • Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., and Charpentier, E. (2012). A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816-821. doi:10.1126/science.1225829
    • (2012) Science , vol.337 , pp. 816-821
    • Jinek, M.1    Chylinski, K.2    Fonfara, I.3    Hauer, M.4    Doudna, J.A.5    Charpentier, E.6
  • 49
    • 69649088962 scopus 로고    scopus 로고
    • Dilution-free analysis from picoliter droplets by nano-electrospray ionization mass spectrometry
    • Kelly, R. T., Page, J. S., Marginean, I., Tang, K., and Smith, R. D. (2009). Dilution-free analysis from picoliter droplets by nano-electrospray ionization mass spectrometry. Angew. Chem. Int. Ed. Engl. 48, 6832-6835. doi:10.1002/anie.200902501
    • (2009) Angew. Chem. Int. Ed. Engl , vol.48 , pp. 6832-6835
    • Kelly, R.T.1    Page, J.S.2    Marginean, I.3    Tang, K.4    Smith, R.D.5
  • 50
    • 85043549520 scopus 로고    scopus 로고
    • Developments in the tools and methodologies of synthetic biology
    • Kelwick, R., Macdonald, J. T., Webb, A. J., and Freemont, P. (2014). Developments in the tools and methodologies of synthetic biology. Front Bioeng. Biotechnol. 2, 60. doi:10.3389/fbioe.2014.00060
    • (2014) Front Bioeng. Biotechnol , vol.2 , pp. 60
    • Kelwick, R.1    Macdonald, J.T.2    Webb, A.J.3    Freemont, P.4
  • 51
    • 84865278391 scopus 로고    scopus 로고
    • Successes and failures in modular genetic engineering
    • Kittleson, J. T., Wu, G. C., and Anderson, J. C. (2012). Successes and failures in modular genetic engineering. Curr. Opin. Chem. Biol. 16, 329-336. doi:10.1016/j.cbpa.2012.06.009
    • (2012) Curr. Opin. Chem. Biol , vol.16 , pp. 329-336
    • Kittleson, J.T.1    Wu, G.C.2    Anderson, J.C.3
  • 52
    • 44249111668 scopus 로고    scopus 로고
    • Application of functional genomics to pathway optimization for increased isoprenoid production
    • Kizer, L., Pitera, D. J., Pfleger, B. F., and Keasling, J. D. (2008). Application of functional genomics to pathway optimization for increased isoprenoid production. Appl. Environ. Microbiol. 74, 3229-3241. doi:10.1128/AEM.02750-07
    • (2008) Appl. Environ. Microbiol , vol.74 , pp. 3229-3241
    • Kizer, L.1    Pitera, D.J.2    Pfleger, B.F.3    Keasling, J.D.4
  • 54
    • 0000096835 scopus 로고    scopus 로고
    • Click chemistry: diverse chemical function from a few good reactions
    • Kolb, H. C., Finn, M. G., and Sharpless, K. B. (2001). Click chemistry: diverse chemical function from a few good reactions. Angew. Chem. Int. Ed. Engl. 40, 2004-2021. doi:10.1002/1521-3773(20010601)40:11<2004::AID-ANIE2004>3.0.CO;2-5
    • (2001) Angew. Chem. Int. Ed. Engl , vol.40 , pp. 2004-2021
    • Kolb, H.C.1    Finn, M.G.2    Sharpless, K.B.3
  • 55
    • 84903748219 scopus 로고    scopus 로고
    • Employing a combinatorial expression approach to characterize xylose utilization in Saccharomyces cerevisiae
    • Latimer, L. N., Lee, M. E., Medina-Cleghorn, D., Kohnz, R. A., Nomura, D. K., and Dueber, J. E. (2014). Employing a combinatorial expression approach to characterize xylose utilization in Saccharomyces cerevisiae. Metab. Eng. 25, 20-29. doi:10.1016/j.ymben.2014.06.002
    • (2014) Metab. Eng , vol.25 , pp. 20-29
    • Latimer, L.N.1    Lee, M.E.2    Medina-Cleghorn, D.3    Kohnz, R.A.4    Nomura, D.K.5    Dueber, J.E.6
  • 56
    • 84864843180 scopus 로고    scopus 로고
    • In silico method for modelling metabolism and gene product expression at genome scale
    • Lerman, J. A., Hyduke, D. R., Latif, H., Portnoy, V. A., Lewis, N. E., Orth, J. D., et al. (2012). In silico method for modelling metabolism and gene product expression at genome scale. Nat. Commun. 3, 929. doi:10.1038/ncomms1928
    • (2012) Nat. Commun , vol.3 , pp. 929
    • Lerman, J.A.1    Hyduke, D.R.2    Latif, H.3    Portnoy, V.A.4    Lewis, N.E.5    Orth, J.D.6
  • 57
    • 84888173486 scopus 로고    scopus 로고
    • Ultrahigh-throughput sorting of microfluidic drops with flow cytometry
    • Lim, S. W., and Abate, A. R. (2013). Ultrahigh-throughput sorting of microfluidic drops with flow cytometry. Lab. Chip 13, 4563-4572. doi:10.1039/c3lc50736j
    • (2013) Lab. Chip , vol.13 , pp. 4563-4572
    • Lim, S.W.1    Abate, A.R.2
  • 58
    • 77949853385 scopus 로고    scopus 로고
    • Development, characterization, and application of paper spray ionization
    • Liu, J., Wang, H., Manicke, N. E., Lin, J. M., Cooks, R. G., and Ouyang, Z. (2010). Development, characterization, and application of paper spray ionization. Anal. Chem. 82, 2463-2471. doi:10.1021/ac902854g
    • (2010) Anal. Chem , vol.82 , pp. 2463-2471
    • Liu, J.1    Wang, H.2    Manicke, N.E.3    Lin, J.M.4    Cooks, R.G.5    Ouyang, Z.6
  • 59
    • 84887523416 scopus 로고    scopus 로고
    • Microfluidic platforms for single-cell protein analysis
    • Liu, Y., and Singh, A. K. (2013). Microfluidic platforms for single-cell protein analysis. J. Lab. Autom. 18, 446-454. doi:10.1177/2211068213494389
    • (2013) J. Lab. Autom , vol.18 , pp. 446-454
    • Liu, Y.1    Singh, A.K.2
  • 60
    • 0038752617 scopus 로고    scopus 로고
    • Computational design of receptor and sensor proteins with novel functions
    • Looger, L. L., Dwyer, M. A., Smith, J. J., and Hellinga, H. W. (2003). Computational design of receptor and sensor proteins with novel functions. Nature 423, 185-190. doi:10.1038/nature01556
    • (2003) Nature , vol.423 , pp. 185-190
    • Looger, L.L.1    Dwyer, M.A.2    Smith, J.J.3    Hellinga, H.W.4
  • 62
    • 80555123167 scopus 로고    scopus 로고
    • Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases
    • Ma, S. M., Garcia, D. E., Redding-Johanson, A. M., Friedland, G. D., Chan, R., Batth, T. S., et al. (2011). Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases. Metab. Eng. 13, 588-597. doi:10.1016/j.ymben.2011.07.001
    • (2011) Metab. Eng , vol.13 , pp. 588-597
    • Ma, S.M.1    Garcia, D.E.2    Redding-Johanson, A.M.3    Friedland, G.D.4    Chan, R.5    Batth, T.S.6
  • 63
    • 78449279126 scopus 로고    scopus 로고
    • Experimental design and statistical methods for improved hit detection in high-throughput screening
    • Malo, N., Hanley, J. A., Carlile, G., Liu, J., Pelletier, J., Thomas, D., et al. (2010). Experimental design and statistical methods for improved hit detection in high-throughput screening. J. Biomol. Screen. 15, 990-1000. doi:10.1177/1087057110377497
    • (2010) J. Biomol. Screen , vol.15 , pp. 990-1000
    • Malo, N.1    Hanley, J.A.2    Carlile, G.3    Liu, J.4    Pelletier, J.5    Thomas, D.6
  • 64
    • 32344448950 scopus 로고    scopus 로고
    • Statistical practice in high-throughput screening data analysis
    • Malo, N., Hanley, J. A., Cerquozzi, S., Pelletier, J., and Nadon, R. (2006). Statistical practice in high-throughput screening data analysis. Nat. Biotechnol. 24, 167-175. doi:10.1038/nbt1186
    • (2006) Nat. Biotechnol , vol.24 , pp. 167-175
    • Malo, N.1    Hanley, J.A.2    Cerquozzi, S.3    Pelletier, J.4    Nadon, R.5
  • 65
    • 84865718193 scopus 로고    scopus 로고
    • Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses
    • McAlister, G. C., Huttlin, E. L., Haas, W., Ting, L., Jedrychowski, M. P., Rogers, J. C., et al. (2012). Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses. Anal. Chem. 84, 7469-7478. doi:10.1021/ac301572t
    • (2012) Anal. Chem , vol.84 , pp. 7469-7478
    • McAlister, G.C.1    Huttlin, E.L.2    Haas, W.3    Ting, L.4    Jedrychowski, M.P.5    Rogers, J.C.6
  • 66
    • 84879002382 scopus 로고    scopus 로고
    • Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli
    • McCloskey, D., Palsson, B. O., and Feist, A. M. (2013). Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli. Mol. Syst. Biol. 9, 661. doi:10.1038/msb.2013.18
    • (2013) Mol. Syst. Biol , vol.9 , pp. 661
    • McCloskey, D.1    Palsson, B.O.2    Feist, A.M.3
  • 67
    • 84919683283 scopus 로고    scopus 로고
    • A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesis
    • Medema, M. H., Cimermancic, P., Sali, A., Takano, E., and Fischbach, M. A. (2014). A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesis. PLoS Comput. Biol. 10, e1004016. doi:10.1371/journal.pcbi.1004016
    • (2014) PLoS Comput. Biol , vol.10
    • Medema, M.H.1    Cimermancic, P.2    Sali, A.3    Takano, E.4    Fischbach, M.A.5
  • 68
    • 79951522331 scopus 로고    scopus 로고
    • Practical 4'-phosphopantetheine active site discovery from proteomic samples
    • Meier, J. L., Patel, A. D., Niessen, S., Meehan, M., Kersten, R., Yang, J. Y., et al. (2011). Practical 4'-phosphopantetheine active site discovery from proteomic samples. J. Proteome Res. 10, 320-329. doi:10.1021/pr100953b
    • (2011) J. Proteome Res , vol.10 , pp. 320-329
    • Meier, J.L.1    Patel, A.D.2    Niessen, S.3    Meehan, M.4    Kersten, R.5    Yang, J.Y.6
  • 69
    • 84857050180 scopus 로고    scopus 로고
    • Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways
    • Michener, J. K., Thodey, K., Liang, J. C., and Smolke, C. D. (2012). Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab. Eng. 14, 212-222. doi:10.1016/j.ymben.2011.09.004
    • (2012) Metab. Eng , vol.14 , pp. 212-222
    • Michener, J.K.1    Thodey, K.2    Liang, J.C.3    Smolke, C.D.4
  • 70
    • 84875720517 scopus 로고    scopus 로고
    • Precise and reliable gene expression via standard transcription and translation initiation elements
    • Mutalik, V. K., Guimaraes, J. C., Cambray, G., Lam, C., Christoffersen, M. J., Mai, Q. A., et al. (2013). Precise and reliable gene expression via standard transcription and translation initiation elements. Nat. Methods 10, 354-360. doi:10.1038/nmeth.2404
    • (2013) Nat. Methods , vol.10 , pp. 354-360
    • Mutalik, V.K.1    Guimaraes, J.C.2    Cambray, G.3    Lam, C.4    Christoffersen, M.J.5    Mai, Q.A.6
  • 72
  • 73
    • 0033662220 scopus 로고    scopus 로고
    • DNA microarray detection of metabolic responses to protein overproduction in Escherichia coli
    • Oh, M. K., and Liao, J. C. (2000). DNA microarray detection of metabolic responses to protein overproduction in Escherichia coli. Metab. Eng. 2, 201-209. doi:10.1006/mben.2000.0149
    • (2000) Metab. Eng , vol.2 , pp. 201-209
    • Oh, M.K.1    Liao, J.C.2
  • 74
    • 84876784070 scopus 로고    scopus 로고
    • High-level semi-synthetic production of the potent antimalarial artemisinin
    • Paddon, C. J., Westfall, P. J., Pitera, D. J., Benjamin, K., Fisher, K., Mcphee, D., et al. (2013). High-level semi-synthetic production of the potent antimalarial artemisinin. Nature 496, 528-532. doi:10.1038/nature12051
    • (2013) Nature , vol.496 , pp. 528-532
    • Paddon, C.J.1    Westfall, P.J.2    Pitera, D.J.3    Benjamin, K.4    Fisher, K.5    Mcphee, D.6
  • 76
    • 33747078696 scopus 로고    scopus 로고
    • Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes
    • Pfleger, B. F., Pitera, D. J., Smolke, C. D., and Keasling, J. D. (2006). Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes. Nat. Biotechnol. 24, 1027-1032. doi:10.1038/nbt1226
    • (2006) Nat. Biotechnol , vol.24 , pp. 1027-1032
    • Pfleger, B.F.1    Pitera, D.J.2    Smolke, C.D.3    Keasling, J.D.4
  • 77
    • 84861990380 scopus 로고    scopus 로고
    • Selected reaction monitoring-based proteomics: workflows, potential, pitfalls and future directions
    • Picotti, P., and Aebersold, R. (2012). Selected reaction monitoring-based proteomics: workflows, potential, pitfalls and future directions. Nat. Methods 9, 555-566. doi:10.1038/nmeth.2015
    • (2012) Nat. Methods , vol.9 , pp. 555-566
    • Picotti, P.1    Aebersold, R.2
  • 78
    • 68749094119 scopus 로고    scopus 로고
    • Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics
    • Picotti, P., Bodenmiller, B., Mueller, L. N., Domon, B., and Aebersold, R. (2009). Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics. Cell 138, 795-806. doi:10.1016/j.cell.2009.05.051
    • (2009) Cell , vol.138 , pp. 795-806
    • Picotti, P.1    Bodenmiller, B.2    Mueller, L.N.3    Domon, B.4    Aebersold, R.5
  • 79
    • 84922804451 scopus 로고    scopus 로고
    • Divergent mechanistic routes for the formation of gem-dimethyl groups in the biosynthesis of complex polyketides
    • Poust, S., Phelan, R. M., Deng, K., Katz, L., Petzold, C. J., and Keasling, J. D. (2015). Divergent mechanistic routes for the formation of gem-dimethyl groups in the biosynthesis of complex polyketides. Angew. Chem. Int. Ed. Engl. 54, 2370-2373. doi:10.1002/anie.201410124
    • (2015) Angew. Chem. Int. Ed. Engl , vol.54 , pp. 2370-2373
    • Poust, S.1    Phelan, R.M.2    Deng, K.3    Katz, L.4    Petzold, C.J.5    Keasling, J.D.6
  • 80
    • 79551571018 scopus 로고    scopus 로고
    • Metabolomics in systems microbiology
    • Reaves, M. L., and Rabinowitz, J. D. (2011). Metabolomics in systems microbiology. Curr. Opin. Biotechnol. 22, 17-25. doi:10.1016/j.copbio.2010.10.001
    • (2011) Curr. Opin. Biotechnol , vol.22 , pp. 17-25
    • Reaves, M.L.1    Rabinowitz, J.D.2
  • 81
    • 79952108014 scopus 로고    scopus 로고
    • Targeted proteomics for metabolic pathway optimization: application to terpene production
    • Redding-Johanson, A. M., Batth, T. S., Chan, R., Krupa, R., Szmidt, H. L., Adams, P. D., et al. (2011). Targeted proteomics for metabolic pathway optimization: application to terpene production. Metab. Eng. 13, 194-203. doi:10.1016/j.ymben.2010.12.005
    • (2011) Metab. Eng , vol.13 , pp. 194-203
    • Redding-Johanson, A.M.1    Batth, T.S.2    Chan, R.3    Krupa, R.4    Szmidt, H.L.5    Adams, P.D.6
  • 82
    • 84866158885 scopus 로고    scopus 로고
    • Efficient experimental design and analysis strategies for the detection of differential expression using RNA-sequencing
    • Robles, J. A., Qureshi, S. E., Stephen, S. J., Wilson, S. R., Burden, C. J., and Taylor, J. M. (2012). Efficient experimental design and analysis strategies for the detection of differential expression using RNA-sequencing. BMC Genomics 13, 484. doi:10.1186/1471-2164-13-484
    • (2012) BMC Genomics , vol.13 , pp. 484
    • Robles, J.A.1    Qureshi, S.E.2    Stephen, S.J.3    Wilson, S.R.4    Burden, C.J.5    Taylor, J.M.6
  • 84
    • 84906228597 scopus 로고    scopus 로고
    • Single-cell RNA-seq: advances and future challenges
    • Saliba, A. E., Westermann, A. J., Gorski, S. A., and Vogel, J. (2014). Single-cell RNA-seq: advances and future challenges. Nucleic Acids Res. 42, 8845-8860. doi:10.1093/nar/gku555
    • (2014) Nucleic Acids Res , vol.42 , pp. 8845-8860
    • Saliba, A.E.1    Westermann, A.J.2    Gorski, S.A.3    Vogel, J.4
  • 85
    • 70349964350 scopus 로고    scopus 로고
    • Automated design of synthetic ribosome binding sites to control protein expression
    • Salis, H. M., Mirsky, E. A., and Voigt, C. A. (2009). Automated design of synthetic ribosome binding sites to control protein expression. Nat. Biotechnol. 27, 946-950. doi:10.1038/nbt.1568
    • (2009) Nat. Biotechnol , vol.27 , pp. 946-950
    • Salis, H.M.1    Mirsky, E.A.2    Voigt, C.A.3
  • 86
    • 70349985735 scopus 로고    scopus 로고
    • Microbial production of 1,3-propanediol: recent developments and emerging opportunities
    • Saxena, R. K., Anand, P., Saran, S., and Isar, J. (2009). Microbial production of 1,3-propanediol: recent developments and emerging opportunities. Biotechnol. Adv. 27, 895-913. doi:10.1016/j.biotechadv.2009.07.003
    • (2009) Biotechnol. Adv , vol.27 , pp. 895-913
    • Saxena, R.K.1    Anand, P.2    Saran, S.3    Isar, J.4
  • 87
    • 79551662521 scopus 로고    scopus 로고
    • Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0
    • Schellenberger, J., Que, R., Fleming, R. M., Thiele, I., Orth, J. D., Feist, A. M., et al. (2011). Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0. Nat. Protoc. 6, 1290-1307. doi:10.1038/nprot.2011.308
    • (2011) Nat. Protoc , vol.6 , pp. 1290-1307
    • Schellenberger, J.1    Que, R.2    Fleming, R.M.3    Thiele, I.4    Orth, J.D.5    Feist, A.M.6
  • 88
    • 38749141010 scopus 로고    scopus 로고
    • Ultrasensitive electrochemical immunosensing using magnetic beads and gold nanocatalysts
    • Selvaraju, T., Das, J., Han, S. W., and Yang, H. (2008). Ultrasensitive electrochemical immunosensing using magnetic beads and gold nanocatalysts. Biosens. Bioelectron. 23, 932-938. doi:10.1016/j.bios.2007.09.010
    • (2008) Biosens. Bioelectron , vol.23 , pp. 932-938
    • Selvaraju, T.1    Das, J.2    Han, S.W.3    Yang, H.4
  • 89
    • 27744450286 scopus 로고    scopus 로고
    • i-Tracker: for quantitative proteomics using iTRAQ
    • Shadforth, I. P., Dunkley, T. P., Lilley, K. S., and Bessant, C. (2005). i-Tracker: for quantitative proteomics using iTRAQ. BMC Genomics 6, 145. doi:10.1186/1471-2164-6-145
    • (2005) BMC Genomics , vol.6 , pp. 145
    • Shadforth, I.P.1    Dunkley, T.P.2    Lilley, K.S.3    Bessant, C.4
  • 90
    • 84915750351 scopus 로고    scopus 로고
    • A droplet-to-digital (D2D) microfluidic device for single cell assays
    • Shih, S. C., Gach, P. C., Sustarich, J., Simmons, B. A., Adams, P. D., Singh, S., et al. (2015). A droplet-to-digital (D2D) microfluidic device for single cell assays. Lab. Chip 15, 225-236. doi:10.1039/c4lc00794h
    • (2015) Lab. Chip , vol.15 , pp. 225-236
    • Shih, S.C.1    Gach, P.C.2    Sustarich, J.3    Simmons, B.A.4    Adams, P.D.5    Singh, S.6
  • 91
    • 84886485785 scopus 로고    scopus 로고
    • Engineering the esaR promoter for tunable quorum sensing-dependent gene expression
    • Shong, J., and Collins, C. H. (2013). Engineering the esaR promoter for tunable quorum sensing-dependent gene expression. ACS. Synth. Biol. 2, 568-575. doi:10.1021/sb4000433
    • (2013) ACS. Synth. Biol , vol.2 , pp. 568-575
    • Shong, J.1    Collins, C.H.2
  • 92
    • 44649153450 scopus 로고    scopus 로고
    • Rewiring the specificity of two-component signal transduction systems
    • Skerker, J. M., Perchuk, B. S., Siryaporn, A., Lubin, E. A., Ashenberg, O., Goulian, M., et al. (2008). Rewiring the specificity of two-component signal transduction systems. Cell 133, 1043-1054. doi:10.1016/j.cell.2008.04.040
    • (2008) Cell , vol.133 , pp. 1043-1054
    • Skerker, J.M.1    Perchuk, B.S.2    Siryaporn, A.3    Lubin, E.A.4    Ashenberg, O.5    Goulian, M.6
  • 93
    • 84921517479 scopus 로고    scopus 로고
    • Functional optimization of gene clusters by combinatorial design and assembly
    • Smanski, M. J., Bhatia, S., Zhao, D., Park, Y., and B A Woodruff, L. (2014). Functional optimization of gene clusters by combinatorial design and assembly. Nat. Biotechnol. 32, 1241-1249. doi:10.1038/nbt.3063
    • (2014) Nat. Biotechnol , vol.32 , pp. 1241-1249
    • Smanski, M.J.1    Bhatia, S.2    Zhao, D.3    Park, Y.4    Woodruff, L.B.A.5
  • 94
    • 70349634435 scopus 로고    scopus 로고
    • Quantitative phenotyping via deep barcode sequencing
    • Smith, A. M., Heisler, L. E., Mellor, J., Kaper, F., Thompson, M. J., Chee, M., et al. (2009). Quantitative phenotyping via deep barcode sequencing. Genome Res. 19, 1836-1842. doi:10.1101/gr.093955.109
    • (2009) Genome Res , vol.19 , pp. 1836-1842
    • Smith, A.M.1    Heisler, L.E.2    Mellor, J.3    Kaper, F.4    Thompson, M.J.5    Chee, M.6
  • 95
    • 81355139629 scopus 로고    scopus 로고
    • Choosing an effective protein bioconjugation strategy
    • Stephanopoulos, N., and Francis, M. B. (2011). Choosing an effective protein bioconjugation strategy. Nat. Chem. Biol. 7, 876-884. doi:10.1038/nchembio.720
    • (2011) Nat. Chem. Biol , vol.7 , pp. 876-884
    • Stephanopoulos, N.1    Francis, M.B.2
  • 96
    • 78650896342 scopus 로고    scopus 로고
    • Multichromatic control of gene expression in Escherichia coli
    • Tabor, J. J., Levskaya, A., and Voigt, C. A. (2011). Multichromatic control of gene expression in Escherichia coli. J. Mol. Biol. 405, 315-324. doi:10.1016/j.jmb.2010.10.038
    • (2011) J. Mol. Biol , vol.405 , pp. 315-324
    • Tabor, J.J.1    Levskaya, A.2    Voigt, C.A.3
  • 98
    • 79251580632 scopus 로고    scopus 로고
    • Design and application of a mevalonate-responsive regulatory protein
    • Tang, S. Y., and Cirino, P. C. (2011). Design and application of a mevalonate-responsive regulatory protein. Angew. Chem. Int. Ed. Engl. 50, 1084-1086. doi:10.1002/anie.201006083
    • (2011) Angew. Chem. Int. Ed. Engl , vol.50 , pp. 1084-1086
    • Tang, S.Y.1    Cirino, P.C.2
  • 99
    • 33750456480 scopus 로고    scopus 로고
    • Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells
    • Tibes, R., Qiu, Y., Lu, Y., Hennessy, B., Andreeff, M., Mills, G. B., et al. (2006). Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells. Mol. Cancer Ther. 5, 2512-2521. doi:10.1158/1535-7163.MCT-06-0334
    • (2006) Mol. Cancer Ther , vol.5 , pp. 2512-2521
    • Tibes, R.1    Qiu, Y.2    Lu, Y.3    Hennessy, B.4    Andreeff, M.5    Mills, G.B.6
  • 100
    • 84879223038 scopus 로고    scopus 로고
    • Reporter-based screening and selection of enzymes
    • Van Rossum, T., Kengen, S. W., and Van Der Oost, J. (2013). Reporter-based screening and selection of enzymes. FEBS J. 280, 2979-2996. doi:10.1111/febs.12281
    • (2013) FEBS J , vol.280 , pp. 2979-2996
    • Van Rossum, T.1    Kengen, S.W.2    Van Der Oost, J.3
  • 101
    • 84884920570 scopus 로고    scopus 로고
    • Label-free high-throughput assays to screen and characterize novel lactate dehydrogenase inhibitors
    • Vanderporten, E., Frick, L., Turincio, R., Thana, P., Lamarr, W., and Liu, Y. (2013). Label-free high-throughput assays to screen and characterize novel lactate dehydrogenase inhibitors. Anal. Biochem. 441, 115-122. doi:10.1016/j.ab.2013.07.003
    • (2013) Anal. Biochem , vol.441 , pp. 115-122
    • Vanderporten, E.1    Frick, L.2    Turincio, R.3    Thana, P.4    Lamarr, W.5    Liu, Y.6
  • 102
    • 84900315204 scopus 로고    scopus 로고
    • Microfluidic high-throughput culturing of single cells for selection based on extracellular metabolite production or consumption
    • Wang, B. L., Ghaderi, A., Zhou, H., Agresti, J., Weitz, D. A., Fink, G. R., et al. (2014). Microfluidic high-throughput culturing of single cells for selection based on extracellular metabolite production or consumption. Nat. Biotechnol. 32, 473-478. doi:10.1038/nbt.2857
    • (2014) Nat. Biotechnol , vol.32 , pp. 473-478
    • Wang, B.L.1    Ghaderi, A.2    Zhou, H.3    Agresti, J.4    Weitz, D.A.5    Fink, G.R.6
  • 103
    • 84863328748 scopus 로고    scopus 로고
    • Multiplexed in vivo His-tagging of enzyme pathways for in vitro single-pot multienzyme catalysis
    • Wang, H. H., Huang, P. Y., Xu, G., Haas, W., Marblestone, A., Li, J., et al. (2012). Multiplexed in vivo His-tagging of enzyme pathways for in vitro single-pot multienzyme catalysis. ACS. Synth. Biol. 1, 43-52. doi:10.1021/sb3000029
    • (2012) ACS. Synth. Biol , vol.1 , pp. 43-52
    • Wang, H.H.1    Huang, P.Y.2    Xu, G.3    Haas, W.4    Marblestone, A.5    Li, J.6
  • 104
    • 68949161807 scopus 로고    scopus 로고
    • Programming cells by multiplex genome engineering and accelerated evolution
    • Wang, H. H., Isaacs, F. J., Carr, P. A., Sun, Z. Z., Xu, G., Forest, C. R., et al. (2009). Programming cells by multiplex genome engineering and accelerated evolution. Nature 460, 894-898. doi:10.1038/nature08187
    • (2009) Nature , vol.460 , pp. 894-898
    • Wang, H.H.1    Isaacs, F.J.2    Carr, P.A.3    Sun, Z.Z.4    Xu, G.5    Forest, C.R.6
  • 105
    • 77955459156 scopus 로고    scopus 로고
    • Rapid profiling of a microbial genome using mixtures of barcoded oligonucleotides
    • Warner, J. R., Reeder, P. J., Karimpour-Fard, A., Woodruff, L. B., and Gill, R. T. (2010). Rapid profiling of a microbial genome using mixtures of barcoded oligonucleotides. Nat. Biotechnol. 28, 856-862. doi:10.1038/nbt.1653
    • (2010) Nat. Biotechnol , vol.28 , pp. 856-862
    • Warner, J.R.1    Reeder, P.J.2    Karimpour-Fard, A.3    Woodruff, L.B.4    Gill, R.T.5
  • 106
    • 84918813440 scopus 로고    scopus 로고
    • Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes
    • Weber, T., Charusanti, P., Musiol-Kroll, E. M., Jiang, X., Tong, Y., Kim, H. U., et al. (2015). Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes. Trends Biotechnol. 33, 15-26. doi:10.1016/j.tibtech.2014.10.009
    • (2015) Trends Biotechnol , vol.33 , pp. 15-26
    • Weber, T.1    Charusanti, P.2    Musiol-Kroll, E.M.3    Jiang, X.4    Tong, Y.5    Kim, H.U.6
  • 107
    • 54249113318 scopus 로고    scopus 로고
    • Higher-order cellular information processing with synthetic RNA devices
    • Win, M. N., and Smolke, C. D. (2008). Higher-order cellular information processing with synthetic RNA devices. Science 322, 456-460. doi:10.1126/science.1160311
    • (2008) Science , vol.322 , pp. 456-460
    • Win, M.N.1    Smolke, C.D.2
  • 108
    • 84865288634 scopus 로고    scopus 로고
    • Enzyme-based ultrasensitive electrochemical biosensors
    • Yang, H. (2012). Enzyme-based ultrasensitive electrochemical biosensors. Curr. Opin. Chem. Biol. 16, 422-428. doi:10.1016/j.cbpa.2012.03.015
    • (2012) Curr. Opin. Chem. Biol , vol.16 , pp. 422-428
    • Yang, H.1
  • 109
    • 84885806733 scopus 로고    scopus 로고
    • Microbial production of lactate-containing polyesters
    • Yang, J. E., Choi, S. Y., Shin, J. H., Park, S. J., and Lee, S. Y. (2013). Microbial production of lactate-containing polyesters. Microb. Biotechnol. 6, 621-636. doi:10.1111/1751-7915.12066
    • (2013) Microb. Biotechnol , vol.6 , pp. 621-636
    • Yang, J.E.1    Choi, S.Y.2    Shin, J.H.3    Park, S.J.4    Lee, S.Y.5
  • 110
    • 79959374585 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol
    • Yim, H., Haselbeck, R., Niu, W., Pujol-Baxley, C., Burgard, A., Boldt, J., et al. (2011). Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol. Nat. Chem. Biol. 7, 445-452. doi:10.1038/nchembio.580
    • (2011) Nat. Chem. Biol , vol.7 , pp. 445-452
    • Yim, H.1    Haselbeck, R.2    Niu, W.3    Pujol-Baxley, C.4    Burgard, A.5    Boldt, J.6
  • 111
    • 84859633048 scopus 로고    scopus 로고
    • Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids
    • Zhang, F., Carothers, J. M., and Keasling, J. D. (2012a). Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids. Nat. Biotechnol. 30, 354-359. doi:10.1038/nbt.2149
    • (2012) Nat. Biotechnol , vol.30 , pp. 354-359
    • Zhang, F.1    Carothers, J.M.2    Keasling, J.D.3
  • 112
    • 84869039746 scopus 로고    scopus 로고
    • Enhancing fatty acid production by the expression of the regulatory transcription factor FadR
    • Zhang, F., Ouellet, M., Batth, T. S., Adams, P. D., Petzold, C. J., Mukhopadhyay, A., et al. (2012b). Enhancing fatty acid production by the expression of the regulatory transcription factor FadR. Metab. Eng. 14, 653-660. doi:10.1016/j.ymben.2012.08.009
    • (2012) Metab. Eng , vol.14 , pp. 653-660
    • Zhang, F.1    Ouellet, M.2    Batth, T.S.3    Adams, P.D.4    Petzold, C.J.5    Mukhopadhyay, A.6
  • 113
    • 84876676603 scopus 로고    scopus 로고
    • Engineering E. coli for caffeic acid biosynthesis from renewable sugars
    • Zhang, H., and Stephanopoulos, G. (2013). Engineering E. coli for caffeic acid biosynthesis from renewable sugars. Appl. Microbiol. Biotechnol. 97, 3333-3341. doi:10.1007/s00253-012-4544-8
    • (2013) Appl. Microbiol. Biotechnol , vol.97 , pp. 3333-3341
    • Zhang, H.1    Stephanopoulos, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.