-
1
-
-
37849028683
-
Red Blood Cells Are the Major Source of α-Synuclein in Blood
-
Barbour, R.; Kling, K.; Anderson, J.; Banducci, K.; Cole, T.; Diep, L.; Fox, M.; Goldstein, J.; Soriano, F.; Seubert, P.; et al. Red Blood Cells Are the Major Source of α-Synuclein in Blood. Neurodegener. Dis. 2008, 5, 55-59.
-
(2008)
Neurodegener. Dis
, vol.5
, pp. 55-59
-
-
Barbour, R.1
Kling, K.2
Anderson, J.3
Banducci, K.4
Cole, T.5
Diep, L.6
Fox, M.7
Goldstein, J.8
Soriano, F.9
Seubert, P.10
-
2
-
-
84955515311
-
Structural disorder of monomeric α-synuclein persists in mammalian cells
-
Theillet, F.; Binolfi, A.; Bekei, B.; Martorana, A.; Rose, H.; Stuiver, M.; Verzini, S.; Lorenz, D.; van Rossum, M.; Goldfarb, D.; et al. Structural disorder of monomeric α-synuclein persists in mammalian cells. Nature 2016, 530, 45-50.
-
(2016)
Nature
, vol.530
, pp. 45-50
-
-
Theillet, F.1
Binolfi, A.2
Bekei, B.3
Martorana, A.4
Rose, H.5
Stuiver, M.6
Verzini, S.7
Lorenz, D.8
Van Rossum, M.9
Goldfarb, D.10
-
3
-
-
0029904487
-
NACP, A Protein Implicated in Alzheimer’s Disease and Learning, Is Natively Unfolded
-
Weinreb, P.; Zhen, W.; Poon, A.; Conway, K.; Lansbury, P. NACP, A Protein Implicated in Alzheimer’s Disease and Learning, Is Natively Unfolded. Biochemistry 1996, 35, 13709-13715.
-
(1996)
Biochemistry
, vol.35
, pp. 13709-13715
-
-
Weinreb, P.1
Zhen, W.2
Poon, A.3
Conway, K.4
Lansbury, P.5
-
4
-
-
80555155665
-
The role of α-synuclein in neurotransmission and synaptic plasticity
-
Cheng, F.; Vivacqua, G.; Yu, S. The role of α-synuclein in neurotransmission and synaptic plasticity. J. Chem. Neuroanat. 2011, 42, 242-248.
-
(2011)
J. Chem. Neuroanat
, vol.42
, pp. 242-248
-
-
Cheng, F.1
Vivacqua, G.2
Yu, S.3
-
5
-
-
77957347060
-
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
-
Burre, J.; Sharma, M.; Tsetsenis, T.; Buchman, V.; Etherton, M.; Sudhof, T. α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro. Science 2010, 329, 1663-1667.
-
(2010)
Science
, vol.329
, pp. 1663-1667
-
-
Burre, J.1
Sharma, M.2
Tsetsenis, T.3
Buchman, V.4
Etherton, M.5
Sudhof, T.6
-
6
-
-
0037092442
-
A role for α-synuclein in the regulation of dopamine biosynthesis
-
Perez, R.; Waymire, J.; Lin, E.; Liu, J.; Guo, F.; Zigmond, M. A role for α-synuclein in the regulation of dopamine biosynthesis. J. Neurosci. 2002, 22, 3090-3099.
-
(2002)
J. Neurosci
, vol.22
, pp. 3090-3099
-
-
Perez, R.1
Waymire, J.2
Lin, E.3
Liu, J.4
Guo, F.5
Zigmond, M.6
-
7
-
-
33751113009
-
α-Synuclein Overexpression in PC12 and Chromaffin Cells Impairs Catecholamine Release by Interfering with a Late Step in Exocytosis
-
Larsen, K.; Schmitz, Y.; Troyer, M.; Mosharov, E.; Dietrich, P.; Quazi, A.; Savalle, M.; Nemani, V.; Chaudhry, F.; Edwards, R.; et al. α-Synuclein Overexpression in PC12 and Chromaffin Cells Impairs Catecholamine Release by Interfering with a Late Step in Exocytosis. J. Neurosci. 2006, 26, 11915-11922.
-
(2006)
J. Neurosci
, vol.26
, pp. 11915-11922
-
-
Larsen, K.1
Schmitz, Y.2
Troyer, M.3
Mosharov, E.4
Dietrich, P.5
Quazi, A.6
Savalle, M.7
Nemani, V.8
Chaudhry, F.9
Edwards, R.10
-
8
-
-
33750041624
-
Abnormal compartmentalization of norepinephrine in mouse dentate gyrus in α-synuclein knockout and A30P transgenic mice
-
Yavich, L.; Jäkälä, P.; Tanila, H. Abnormal compartmentalization of norepinephrine in mouse dentate gyrus in α-synuclein knockout and A30P transgenic mice. J. Neurochem. 2006, 99, 724-732.
-
(2006)
J. Neurochem
, vol.99
, pp. 724-732
-
-
Yavich, L.1
Jäkälä, P.2
Tanila, H.3
-
9
-
-
10944243102
-
Role of α-Synuclein in Presynaptic Dopamine Recruitment
-
Yavich, L.; Tanilla, H.; Vepsalainen, S.; Jakala, P. Role of α-Synuclein in Presynaptic Dopamine Recruitment. J. Neurosci. 2004, 24, 11165-11170.
-
(2004)
J. Neurosci
, vol.24
, pp. 11165-11170
-
-
Yavich, L.1
Tanilla, H.2
Vepsalainen, S.3
Jakala, P.4
-
10
-
-
80052398365
-
α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
-
Bartels, T.; Choi, J.; Selkoe, D. α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation. Nature 2011, 477, 107-110.
-
(2011)
Nature
, vol.477
, pp. 107-110
-
-
Bartels, T.1
Choi, J.2
Selkoe, D.3
-
11
-
-
0028277520
-
Identification of two distinct synucleins from human brain
-
Jakes, R.; Spillantini, M.; Goedert, M. Identification of two distinct synucleins from human brain. FEBS Lett. 1994, 345, 27-32.
-
(1994)
FEBS Lett
, vol.345
, pp. 27-32
-
-
Jakes, R.1
Spillantini, M.2
Goedert, M.3
-
12
-
-
84922479429
-
Purification of α-Synuclein from Human Brain Reveals an Instability of Endogenous Multimers as the Protein Approaches Purity
-
Luth, E.; Bartels, T.; Dettmer, U.; Kim, N.; Selkoe, D. Purification of α-Synuclein from Human Brain Reveals an Instability of Endogenous Multimers as the Protein Approaches Purity. Biochemistry 2015, 54, 279-292.
-
(2015)
Biochemistry
, vol.54
, pp. 279-292
-
-
Luth, E.1
Bartels, T.2
Dettmer, U.3
Kim, N.4
Selkoe, D.5
-
13
-
-
84878994255
-
Properties of native brain α-synuclein
-
Burré, J.; Vivona, S.; Diao, J.; Sharma, M.; Brunger, A.; Südhof, T. Properties of native brain α-synuclein. Nature 2013, 498, E4-E6.
-
(2013)
Nature
, vol.498
, pp. E4-E6
-
-
Burré, J.1
Vivona, S.2
Diao, J.3
Sharma, M.4
Brunger, A.5
Südhof, T.6
-
14
-
-
84887921166
-
α-Synucleinopathy phenotypes
-
McCann, H.; Stevens, C.; Cartwright, H.; Halliday, G. α-Synucleinopathy phenotypes. Park. Relat. Disord. 2014, 20, S62-S67.
-
(2014)
Park. Relat. Disord
, vol.20
, pp. S62-S67
-
-
McCann, H.1
Stevens, C.2
Cartwright, H.3
Halliday, G.4
-
15
-
-
84991256087
-
The clinical symptoms of Parkinson’s disease
-
Sveinbjornsdottir, S. The clinical symptoms of Parkinson’s disease. J. Neurochem. 2016, 139, 318-324.
-
(2016)
J. Neurochem
, vol.139
, pp. 318-324
-
-
Sveinbjornsdottir, S.1
-
16
-
-
0027489476
-
Parkinson’s disease and anxiety: Comorbidity with depression
-
Menza, M.; Robertson-Hoffman, D.; Bonapace, A. Parkinson’s disease and anxiety: Comorbidity with depression. Biol. Psychiatry 1993, 34, 465-470.
-
(1993)
Biol. Psychiatry
, vol.34
, pp. 465-470
-
-
Menza, M.1
Robertson-Hoffman, D.2
Bonapace, A.3
-
17
-
-
9144224226
-
Dementia with Lewy bodies
-
McKeith, I.; Mintzer, J.; Aarsland, D.; Burn, D.; Chiu, H.; Cohen-Mansfield, J.; Dickson, D.; Dubois, B.; Duda, J.; Feldman, H.; et al. Dementia with Lewy bodies. Lancet Neurol. 2004, 3, 19-28.
-
(2004)
Lancet Neurol
, vol.3
, pp. 19-28
-
-
McKeith, I.1
Mintzer, J.2
Aarsland, D.3
Burn, D.4
Chiu, H.5
Cohen-Mansfield, J.6
Dickson, D.7
Dubois, B.8
Duda, J.9
Feldman, H.10
-
18
-
-
84920982675
-
Multiple-System Atrophy
-
Longo, D.; Fanciulli, A.; Wenning, G. Multiple-System Atrophy. N. Engl. J. Med. 2015, 372, 249-263.
-
(2015)
N. Engl. J. Med
, vol.372
, pp. 249-263
-
-
Longo, D.1
Fanciulli, A.2
Wenning, G.3
-
19
-
-
82455205801
-
Multiple system atrophy: A clinical and neuropathological perspective
-
Ubhi, K.; Low, P.; Masliah, E. Multiple system atrophy: A clinical and neuropathological perspective. Trends Neurosci. 2011, 34, 581-590.
-
(2011)
Trends Neurosci
, vol.34
, pp. 581-590
-
-
Ubhi, K.1
Low, P.2
Masliah, E.3
-
20
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson’s disease
-
Braak, H.; Tredici, K.; Rüb, U.; de Vos, R.; Jansen Steur, E.; Braak, E. Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol. Aging 2003, 24, 197-211.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Tredici, K.2
Rüb, U.3
De Vos, R.4
Jansen Steur, E.5
Braak, E.6
-
21
-
-
0026326709
-
Progression and survival in Parkinson’s disease
-
Marttila, R.; Rhine, U. Progression and survival in Parkinson’s disease. Acta Neurol. 1991, 136, 24-28.
-
(1991)
Acta Neurol
, vol.136
, pp. 24-28
-
-
Marttila, R.1
Rhine, U.2
-
22
-
-
73449102917
-
Recent developments in multiple system atrophy
-
Wenning, G.; Stefanova, N. Recent developments in multiple system atrophy. J. Neurol. 2009, 256, 1791-1808.
-
(2009)
J. Neurol
, vol.256
, pp. 1791-1808
-
-
Wenning, G.1
Stefanova, N.2
-
23
-
-
33845694258
-
Survival and mortality differences between dementia with Lewy bodies vs. Alzheimer disease
-
Williams, M.; Xiong, C.; Morris, J.; Galvin, J. Survival and mortality differences between dementia with Lewy bodies vs. Alzheimer disease. Neurology 2006, 67, 1935-1941.
-
(2006)
Neurology
, vol.67
, pp. 1935-1941
-
-
Williams, M.1
Xiong, C.2
Morris, J.3
Galvin, J.4
-
24
-
-
0030882856
-
α-Synuclein in Lewy bodies
-
Spillantini, M.; Schmidt, M.; Lee, V.; Trojanowski, J.; Jakes, R.; Goedert, M. α-Synuclein in Lewy bodies. Nature 1997, 388, 839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.1
Schmidt, M.2
Lee, V.3
Trojanowski, J.4
Jakes, R.5
Goedert, M.6
-
25
-
-
41449113168
-
Ubiquitination of α-synuclein and autophagy in Parkinson’s disease
-
Engelender, S. Ubiquitination of α-synuclein and autophagy in Parkinson’s disease. Autophagy 2008, 4, 372-374.
-
(2008)
Autophagy
, vol.4
, pp. 372-374
-
-
Engelender, S.1
-
26
-
-
0033538002
-
Extensive axonal Lewy neurites in Parkinson’s disease: A novel pathological feature revealed by α-synuclein immunocytochemistry
-
Braak, H.; Sandmann-Keil, D.; Gai, W.; Braak, E. Extensive axonal Lewy neurites in Parkinson’s disease: A novel pathological feature revealed by α-synuclein immunocytochemistry. Neurosci. Lett. 1999, 265, 67-69.
-
(1999)
Neurosci. Lett
, vol.265
, pp. 67-69
-
-
Braak, H.1
Sandmann-Keil, D.2
Gai, W.3
Braak, E.4
-
27
-
-
0026563548
-
Filaments of Lewy bodies contain insoluble cytoskeletal elements
-
Galloway, P.; Mulvihill, P.; Perry, G. Filaments of Lewy bodies contain insoluble cytoskeletal elements. Am. J. Pathol. 1992, 140, 809-822.
-
(1992)
Am. J. Pathol
, vol.140
, pp. 809-822
-
-
Galloway, P.1
Mulvihill, P.2
Perry, G.3
-
28
-
-
44649167579
-
Three-Layered Structure Shared Between Lewy Bodies and Lewy Neurites—Three-Dimensional Reconstruction of Triple-Labeled Sections
-
Kanazawa, T.; Uchihara, T.; Takahashi, A.; Nakamura, A.; Orimo, S.; Mizusawa, H. Three-Layered Structure Shared Between Lewy Bodies and Lewy Neurites—Three-Dimensional Reconstruction of Triple-Labeled Sections. Brain Pathol. 2008, 18, 415-422.
-
(2008)
Brain Pathol
, vol.18
, pp. 415-422
-
-
Kanazawa, T.1
Uchihara, T.2
Takahashi, A.3
Nakamura, A.4
Orimo, S.5
Mizusawa, H.6
-
29
-
-
77955906195
-
Athology of neuro-glial α-synucleinopathy (Lewy body disease and multiple system atrophy)
-
Miki, Y.; Mori, F.; Tanji, K.; Wakabayashi, K. Athology of neuro-glial α-synucleinopathy (Lewy body disease and multiple system atrophy). Hirosaki Med. J. 2010, 61, 80-88.
-
(2010)
Hirosaki Med. J
, vol.61
, pp. 80-88
-
-
Miki, Y.1
Mori, F.2
Tanji, K.3
Wakabayashi, K.4
-
30
-
-
0031713491
-
Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α-synuclein
-
Tu, P.; Galvin, J.; Baba, M.; Giasson, B.; Tomita, T.; Leight, S.; Nakajo, S.; Iwatsubo, T.; Trojanowski, J.; Lee, V. Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α-synuclein. Ann. Neurol. 1998, 44, 415-422.
-
(1998)
Ann. Neurol
, vol.44
, pp. 415-422
-
-
Tu, P.1
Galvin, J.2
Baba, M.3
Giasson, B.4
Tomita, T.5
Leight, S.6
Nakajo, S.7
Iwatsubo, T.8
Trojanowski, J.9
Lee, V.10
-
31
-
-
0032584686
-
Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson’s disease and dementia with Lewy bodies
-
Grazia Spillantini, M.; Anthony Crowther, R.; Jakes, R.; Cairns, N.; Lantos, P.; Goedert, M. Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson’s disease and dementia with Lewy bodies. Neurosci. Lett. 1998, 251, 205-208.
-
(1998)
Neurosci. Lett
, vol.251
, pp. 205-208
-
-
Grazia Spillantini, M.1
Anthony Crowther, R.2
Jakes, R.3
Cairns, N.4
Lantos, P.5
Goedert, M.6
-
32
-
-
84855477917
-
The neuropathology, pathophysiology and genetics of multiple system atrophy
-
Ahmed, Z.; Asi, Y.; Sailer, A.; Lees, A.; Houlden, H.; Revesz, T.; Holton, J. The neuropathology, pathophysiology and genetics of multiple system atrophy. Neuropathol. Appl. Neurobiol. 2012, 38, 4-24.
-
(2012)
Neuropathol. Appl. Neurobiol
, vol.38
, pp. 4-24
-
-
Ahmed, Z.1
Asi, Y.2
Sailer, A.3
Lees, A.4
Houlden, H.5
Revesz, T.6
Holton, J.7
-
33
-
-
84898046790
-
α-Synuclein mRNA expression in oligodendrocytes in MSA
-
Asi, Y.; Simpson, J.; Heath, P.; Wharton, S.; Lees, A.; Revesz, T.; Houlden, H.; Holton, J. α-Synuclein mRNA expression in oligodendrocytes in MSA. Glia 2014, 62, 964-970.
-
(2014)
Glia
, vol.62
, pp. 964-970
-
-
Asi, Y.1
Simpson, J.2
Heath, P.3
Wharton, S.4
Lees, A.5
Revesz, T.6
Houlden, H.7
Holton, J.8
-
34
-
-
84954168300
-
α-Synuclein Expression in the Oligodendrocyte Lineage: An In Vitro and In Vivo Study Using Rodent and Human Models
-
Djelloul, M.; Holmqvist, S.; Boza-Serrano, A.; Azevedo, C.; Yeung, M.; Goldwurm, S.; Frisén, J.; Deierborg, T.; Roybon, L. α-Synuclein Expression in the Oligodendrocyte Lineage: An In Vitro and In Vivo Study Using Rodent and Human Models. Stem Cell Rep. 2015, 5, 174-184.
-
(2015)
Stem Cell Rep
, vol.5
, pp. 174-184
-
-
Djelloul, M.1
Holmqvist, S.2
Boza-Serrano, A.3
Azevedo, C.4
Yeung, M.5
Goldwurm, S.6
Frisén, J.7
Deierborg, T.8
Roybon, L.9
-
35
-
-
84878405578
-
G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome
-
Lesage, S.; Anheim, M.; Letournel, F.; Bousset, L.; Honoré, A.; Rozas, N.; Pieri, L.; Madiona, K.; Dürr, A.; Melki, R.; et al. G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome. Ann. Neurol. 2013, 73, 459-471.
-
(2013)
Ann. Neurol
, vol.73
, pp. 459-471
-
-
Lesage, S.1
Anheim, M.2
Letournel, F.3
Bousset, L.4
Honoré, A.5
Rozas, N.6
Pieri, L.7
Madiona, K.8
Dürr, A.9
Melki, R.10
-
36
-
-
0030744876
-
Mutation in the α-Synuclein Gene Identified in Families with Parkinson’s Disease
-
Polymeropoulos, M. Mutation in the α-Synuclein Gene Identified in Families with Parkinson’s Disease. Science 1997, 276, 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.1
-
37
-
-
4644290985
-
α-Synuclein locus duplication as a cause of familial Parkinson’s disease
-
Chartier-Harlin, M.; Kachergus, J.; Roumier, C.; Mouroux, V.; Douay, X.; Lincoln, S.; Levecque, C.; Larvor, L.; Andrieux, J.; Hulihan, M.; et al. α-Synuclein locus duplication as a cause of familial Parkinson’s disease. Lancet 2004, 364, 1167-1169.
-
(2004)
Lancet
, vol.364
, pp. 1167-1169
-
-
Chartier-Harlin, M.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
Levecque, C.7
Larvor, L.8
Andrieux, J.9
Hulihan, M.10
-
38
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson’s disease
-
Simón-Sánchez, J.; Schulte, C.; Bras, J.; Sharma, M.; Gibbs, J.; Berg, D.; Paisan-Ruiz, C.; Lichtner, P.; Scholz, S.; Hernandez, D.; et al. Genome-wide association study reveals genetic risk underlying Parkinson’s disease. Nat. Genet. 2009, 41, 1308-1312.
-
(2009)
Nat. Genet
, vol.41
, pp. 1308-1312
-
-
Simón-Sánchez, J.1
Schulte, C.2
Bras, J.3
Sharma, M.4
Gibbs, J.5
Berg, D.6
Paisan-Ruiz, C.7
Lichtner, P.8
Scholz, S.9
Hernandez, D.10
-
39
-
-
84939599004
-
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease
-
Nalls, M.; Pankratz, N.; Lill, C.; Do, C.; Hernandez, D.; Saad, M.; DeStefano, A.; Kara, E.; Bras, J.; Sharma, M.; et al. Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease. Nat. Genet. 2014, 46, 989-993.
-
(2014)
Nat. Genet
, vol.46
, pp. 989-993
-
-
Nalls, M.1
Pankratz, N.2
Lill, C.3
Do, C.4
Hernandez, D.5
Saad, M.6
Destefano, A.7
Kara, E.8
Bras, J.9
Sharma, M.10
-
40
-
-
70549084415
-
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson’s disease
-
Satake, W.; Nakabayashi, Y.; Mizuta, I.; Hirota, Y.; Ito, C.; Kubo, M.; Kawaguchi, T.; Tsunoda, T.; Watanabe, M.; Takeda, A.; et al. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson’s disease. Nat. Genet. 2009, 41, 1303-1307.
-
(2009)
Nat. Genet
, vol.41
, pp. 1303-1307
-
-
Satake, W.1
Nakabayashi, Y.2
Mizuta, I.3
Hirota, Y.4
Ito, C.5
Kubo, M.6
Kawaguchi, T.7
Tsunoda, T.8
Watanabe, M.9
Takeda, A.10
-
41
-
-
85009731523
-
Calcium: α-Synuclein Interactions in α-Synucleinopathies
-
Rcom-H’cheo-Gauthier, A.; Osborne, S.; Meedeniya, A.; Pountney, D. Calcium: α-Synuclein Interactions in α-Synucleinopathies. Front. Neurosci. 2016, 10, 570.
-
(2016)
Front. Neurosci
, vol.10
, pp. 570
-
-
Rcom-H’cheo-Gauthier, A.1
Osborne, S.2
Meedeniya, A.3
Pountney, D.4
-
42
-
-
0036174010
-
α-Synuclein is phosphorylated in synucleinopathy lesions
-
Fujiwara, H.; Hasegawa, M.; Dohmae, N.; Kawashima, A.; Masliah, E.; Goldberg, M.; Shen, J.; Takio, K.; Iwatsubo, T. α-Synuclein is phosphorylated in synucleinopathy lesions. Nat. Cell Biol. 2002, 4, 160-164.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
Kawashima, A.4
Masliah, E.5
Goldberg, M.6
Shen, J.7
Takio, K.8
Iwatsubo, T.9
-
43
-
-
39849085821
-
Nitrated α-synuclein-activated microglial profiling for Parkinson’s disease
-
Reynolds, A.; Glanzer, J.; Kadiu, I.; Ricardo-Dukelow, M.; Chaudhuri, A.; Ciborowski, P.; Cerny, R.; Gelman, B.; Thomas, M.; Mosley, R.; et al. Nitrated α-synuclein-activated microglial profiling for Parkinson’s disease. J. Neurochem. 2007, 104, 1504-1525.
-
(2007)
J. Neurochem
, vol.104
, pp. 1504-1525
-
-
Reynolds, A.1
Glanzer, J.2
Kadiu, I.3
Ricardo-Dukelow, M.4
Chaudhuri, A.5
Ciborowski, P.6
Cerny, R.7
Gelman, B.8
Thomas, M.9
Mosley, R.10
-
44
-
-
61549111872
-
α-Synuclein and neuronal cell death
-
Cookson, M. α-Synuclein and neuronal cell death. Mol. Neurodegener. 2009, 4, 9.
-
(2009)
Mol. Neurodegener
, vol.4
, pp. 9
-
-
Cookson, M.1
-
45
-
-
33749570292
-
Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body Disease
-
Anderson, J.; Walker, D.; Goldstein, J.; de Laat, R.; Banducci, K.; Caccavello, R.; Barbour, R.; Huang, J.; Kling, K.; Lee, M.; et al. Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body Disease. J. Biol. Chem. 2006, 281, 29739-29752.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 29739-29752
-
-
Anderson, J.1
Walker, D.2
Goldstein, J.3
De Laat, R.4
Banducci, K.5
Caccavello, R.6
Barbour, R.7
Huang, J.8
Kling, K.9
Lee, M.10
-
46
-
-
0027489773
-
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease
-
Ueda, K.; Fukushima, H.; Masliah, E.; Xia, Y.; Iwai, A.; Yoshimoto, M.; Otero, D.; Kondo, J.; Ihara, Y.; Saitoh, T. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc. Natl. Acad. Sci. USA 1993, 90, 11282-11286.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11282-11286
-
-
Ueda, K.1
Fukushima, H.2
Masliah, E.3
Xia, Y.4
Iwai, A.5
Yoshimoto, M.6
Otero, D.7
Kondo, J.8
Ihara, Y.9
Saitoh, T.10
-
47
-
-
84892150877
-
Structural and functional characterization of two α-synuclein strains
-
Bousset, L.; Pieri, L.; Ruiz-Arlandis, G.; Gath, J.; Jensen, P.; Habenstein, B.; Madiona, K.; Olieric, V.; Böckmann, A.; Meier, B.; et al. Structural and functional characterization of two α-synuclein strains. Nat. Commun. 2013, 4, 2575.
-
(2013)
Nat. Commun
, vol.4
, pp. 2575
-
-
Bousset, L.1
Pieri, L.2
Ruiz-Arlandis, G.3
Gath, J.4
Jensen, P.5
Habenstein, B.6
Madiona, K.7
Olieric, V.8
Böckmann, A.9
Meier, B.10
-
48
-
-
0037404112
-
α-Synuclein fibrils constitute the central core of oligodendroglial inclusion filaments in multiple system atrophy
-
Gai, W.; Pountney, D.; Power, J.; Li, Q.; Culvenor, J.; McLean, C.; Jensen, P.; Blumbergs, P. α-Synuclein fibrils constitute the central core of oligodendroglial inclusion filaments in multiple system atrophy. Exp. Neurol. 2003, 181, 68-78.
-
(2003)
Exp. Neurol
, vol.181
, pp. 68-78
-
-
Gai, W.1
Pountney, D.2
Power, J.3
Li, Q.4
Culvenor, J.5
McLean, C.6
Jensen, P.7
Blumbergs, P.8
-
49
-
-
3142664614
-
Annular α-synuclein species from purified multiple system atrophy inclusions
-
Pountney, D.; Lowe, R.; Quilty, M.; Vickers, J.; Voelcker, N.; Gai, W. Annular α-synuclein species from purified multiple system atrophy inclusions. J. Neurochem. 2004, 90, 502-512.
-
(2004)
J. Neurochem
, vol.90
, pp. 502-512
-
-
Pountney, D.1
Lowe, R.2
Quilty, M.3
Vickers, J.4
Voelcker, N.5
Gai, W.6
-
50
-
-
34249052533
-
MRI derived brain atrophy in PSP and MSA-P
-
Paviour, D.; Price, S.; Lees, A.; Fox, N. MRI derived brain atrophy in PSP and MSA-P. J. Neurol. 2007, 254, 478-481.
-
(2007)
J. Neurol
, vol.254
, pp. 478-481
-
-
Paviour, D.1
Price, S.2
Lees, A.3
Fox, N.4
-
51
-
-
85019814430
-
Progression of α-synuclein pathology in multiple system atrophy of the cerebellar type
-
Brettschneider, J.; Irwin, D.; Boluda, S.; Byrne, M.; Fang, L.; Lee, E.; Robinson, J.; Suh, E.; van Deerlin, V.; Toledo, J.; et al. Progression of α-synuclein pathology in multiple system atrophy of the cerebellar type. Neuropathol. Appl. Neurobiol. 2016.
-
(2016)
Neuropathol. Appl. Neurobiol
-
-
Brettschneider, J.1
Irwin, D.2
Boluda, S.3
Byrne, M.4
Fang, L.5
Lee, E.6
Robinson, J.7
Suh, E.8
Van Deerlin, V.9
Toledo, J.10
-
52
-
-
33144489150
-
Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium
-
McKeith, I.; Dickson, D.; Lowe, J.; Emre, M.; O’Brien, J.; Feldman, H.; Cummings, J.; Duda, J.; Lippa, C.; Perry, E.; et al. Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium. Neurology 2005, 65, 1863-1872.
-
(2005)
Neurology
, vol.65
, pp. 1863-1872
-
-
McKeith, I.1
Dickson, D.2
Lowe, J.3
Emre, M.4
O’Brien, J.5
Feldman, H.6
Cummings, J.7
Duda, J.8
Lippa, C.9
Perry, E.10
-
53
-
-
84934983329
-
α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
-
Peelaerts, W.; Bousset, L.; van der Perren, A.; Moskalyuk, A.; Pulizzi, R.; Giugliano, M.; van den Haute, C.; Melki, R.; Baekelandt, V. α-Synuclein strains cause distinct synucleinopathies after local and systemic administration. Nature 2015, 522, 340-344.
-
(2015)
Nature
, vol.522
, pp. 340-344
-
-
Peelaerts, W.1
Bousset, L.2
Van Der Perren, A.3
Moskalyuk, A.4
Pulizzi, R.5
Giugliano, M.6
Van Den Haute, C.7
Melki, R.8
Baekelandt, V.9
-
54
-
-
84869109864
-
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
-
Luk, K.; Kehm, V.; Carroll, J.; Zhang, B.; O’Brien, P.; Trojanowski, J.; Lee, V. Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice. Science 2012, 338, 949-953.
-
(2012)
Science
, vol.338
, pp. 949-953
-
-
Luk, K.1
Kehm, V.2
Carroll, J.3
Zhang, B.4
O’Brien, P.5
Trojanowski, J.6
Lee, V.7
-
55
-
-
84924554924
-
Progressive Aggregation of α-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism
-
Osterberg, V.; Spinelli, K.; Weston, L.; Luk, K.; Woltjer, R.; Unni, V. Progressive Aggregation of α-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism. Cell Rep. 2015, 10, 1252-1260.
-
(2015)
Cell Rep
, vol.10
, pp. 1252-1260
-
-
Osterberg, V.1
Spinelli, K.2
Weston, L.3
Luk, K.4
Woltjer, R.5
Unni, V.6
-
56
-
-
84934955012
-
Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration
-
Paumier, K.; Luk, K.; Manfredsson, F.; Kanaan, N.; Lipton, J.; Collier, T.; Steece-Collier, K.; Kemp, C.; Celano, S.; Schulz, E.; et al. Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration. Neurobiol. Dis. 2015, 82, 185-199.
-
(2015)
Neurobiol. Dis
, vol.82
, pp. 185-199
-
-
Paumier, K.1
Luk, K.2
Manfredsson, F.3
Kanaan, N.4
Lipton, J.5
Collier, T.6
Steece-Collier, K.7
Kemp, C.8
Celano, S.9
Schulz, E.10
-
57
-
-
85005777549
-
Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein
-
Sacino, A.; Brooks, M.; McGarvey, N.; McKinney, A.; Thomas, M.; Levites, Y.; Ran, Y.; Golde, T.; Giasson, B. Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein. Acta Neuropathol. Commun. 2013, 1, 38.
-
(2013)
Acta Neuropathol. Commun
, vol.1
, pp. 38
-
-
Sacino, A.1
Brooks, M.2
McGarvey, N.3
McKinney, A.4
Thomas, M.5
Levites, Y.6
Ran, Y.7
Golde, T.8
Giasson, B.9
-
58
-
-
84984787903
-
Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease
-
Rey, N.L.; Steiner, J.A.; Maroof, N.; Luk, K.C.; Madaj, Z.; Trojanowski, J.Q.; Lee, V.M.; Brundin, P. Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease. J. Exp. Med. 2016, 213, 1759-1778.
-
(2016)
J. Exp. Med
, vol.213
, pp. 1759-1778
-
-
Rey, N.L.1
Steiner, J.A.2
Maroof, N.3
Luk, K.C.4
Madaj, Z.5
Trojanowski, J.Q.6
Lee, V.M.7
Brundin, P.8
-
59
-
-
40449120471
-
Prion Diseases: From Protein to Cell Pathology
-
Kovacs, G.; Budka, H. Prion Diseases: From Protein to Cell Pathology. Am. J. Pathol. 2008, 172, 555-565.
-
(2008)
Am. J. Pathol
, vol.172
, pp. 555-565
-
-
Kovacs, G.1
Budka, H.2
-
60
-
-
84939506533
-
Alzheimer’s and Parkinson’s diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein
-
Goedert, M. Alzheimer’s and Parkinson’s diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein. Science 2015, 349.
-
(2015)
Science
, vol.349
-
-
Goedert, M.1
-
61
-
-
0034718160
-
Properties of NACP/α-synuclein and its role in Alzheimer’s disease
-
Iwai, A. Properties of NACP/α-synuclein and its role in Alzheimer’s disease. Biochim. Biophys. Acta Mol. Basis Dis. 2000, 1502, 95-109.
-
(2000)
Biochim. Biophys. Acta Mol. Basis Dis
, vol.1502
, pp. 95-109
-
-
Iwai, A.1
-
62
-
-
84942522975
-
Structure of the toxic core of α-synuclein from invisible crystals
-
Rodriguez, J.; Ivanova, M.; Sawaya, M.; Cascio, D.; Reyes, F.; Shi, D.; Sangwan, S.; Guenther, E.; Johnson, L.; Zhang, M.; et al. Structure of the toxic core of α-synuclein from invisible crystals. Nature 2015, 525, 486-490.
-
(2015)
Nature
, vol.525
, pp. 486-490
-
-
Rodriguez, J.1
Ivanova, M.2
Sawaya, M.3
Cascio, D.4
Reyes, F.5
Shi, D.6
Sangwan, S.7
Guenther, E.8
Johnson, L.9
Zhang, M.10
-
63
-
-
84924244777
-
The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to α-synuclein inclusions
-
Radford, R.; RcomH’cheo-Gauthier, A.; Wong, M.B.; Eaton, E.D.; Quilty, M.; Blizzard, C.; Norazit, A.; Meedeniya, A.; Vickers, J.C.; Gai, W.P.; et al. The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to α-synuclein inclusions. Mol. Cell Neurosci. 2015, 65, 68-81.
-
(2015)
Mol. Cell Neurosci
, vol.65
, pp. 68-81
-
-
Radford, R.1
Rcomh’cheo-Gauthier, A.2
Wong, M.B.3
Eaton, E.D.4
Quilty, M.5
Blizzard, C.6
Norazit, A.7
Meedeniya, A.8
Vickers, J.C.9
Gai, W.P.10
-
64
-
-
84897977607
-
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
-
Recasens, A.; Dehay, B.; Bové, J.; Carballo-Carbajal, I.; Dovero, S.; Pérez-Villalba, A.; Fernagut, P.; Blesa, J.; Parent, A.; Perier, C.; et al. Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Ann. Neurol. 2014, 75, 351-362.
-
(2014)
Ann. Neurol
, vol.75
, pp. 351-362
-
-
Recasens, A.1
Dehay, B.2
Bové, J.3
Carballo-Carbajal, I.4
Dovero, S.5
Pérez-Villalba, A.6
Fernagut, P.7
Blesa, J.8
Parent, A.9
Perier, C.10
-
65
-
-
84942860108
-
Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
-
Prusiner, S.; Woerman, A.; Mordes, D.; Watts, J.; Rampersaud, R.; Berry, D.; Patel, S.; Oehler, A.; Lowe, J.; Kravitz, S.; et al. Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism. Proc. Natl. Acad. Sci. USA 2015, 112, E5308-E5317.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. E5308-E5317
-
-
Prusiner, S.1
Woerman, A.2
Mordes, D.3
Watts, J.4
Rampersaud, R.5
Berry, D.6
Patel, S.7
Oehler, A.8
Lowe, J.9
Kravitz, S.10
-
66
-
-
84940062763
-
Expanding the spectrum of neuronal pathology in multiple system atrophy
-
Cykowski, M.; Coon, E.; Powell, S.; Jenkins, S.; Benarroch, E.; Low, P.; Schmeichel, A.; Parisi, J. Expanding the spectrum of neuronal pathology in multiple system atrophy. Brain 2015, 138, 2293-2309.
-
(2015)
Brain
, vol.138
, pp. 2293-2309
-
-
Cykowski, M.1
Coon, E.2
Powell, S.3
Jenkins, S.4
Benarroch, E.5
Low, P.6
Schmeichel, A.7
Parisi, J.8
-
67
-
-
43249110200
-
Lewy bodies in grafted neurons in subjects with Parkinson’s disease suggest host-to-graft disease propagation
-
Li, J.; Englund, E.; Holton, J.; Soulet, D.; Hagell, P.; Lees, A.; Lashley, T.; Quinn, N.; Rehncrona, S.; Björklund, A.; et al. Lewy bodies in grafted neurons in subjects with Parkinson’s disease suggest host-to-graft disease propagation. Nat. Med. 2008, 14, 501-503.
-
(2008)
Nat. Med
, vol.14
, pp. 501-503
-
-
Li, J.1
Englund, E.2
Holton, J.3
Soulet, D.4
Hagell, P.5
Lees, A.6
Lashley, T.7
Quinn, N.8
Rehncrona, S.9
Björklund, A.10
-
68
-
-
43249114934
-
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson’s disease
-
Kordower, J.; Chu, Y.; Hauser, R.; Freeman, T.; Olanow, C. Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson’s disease. Nat. Med. 2008, 14, 504-506.
-
(2008)
Nat. Med
, vol.14
, pp. 504-506
-
-
Kordower, J.1
Chu, Y.2
Hauser, R.3
Freeman, T.4
Olanow, C.5
-
69
-
-
84980053683
-
Relationship of neighboring tissue and gliosis to α-synuclein pathology in a fetal transplant for Parkinson’s disease
-
Ahn, T.; Langston, J.; Aachi, V.; Dickson, D. Relationship of neighboring tissue and gliosis to α-synuclein pathology in a fetal transplant for Parkinson’s disease. Am. J. Neurodegener. Dis. 2012, 1, 49-59.
-
(2012)
Am. J. Neurodegener. Dis
, vol.1
, pp. 49-59
-
-
Ahn, T.1
Langston, J.2
Aachi, V.3
Dickson, D.4
-
70
-
-
33645833848
-
Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease
-
El-Agnaf, O.; Salem, S.; Paleologou, K.; Curran, M.; Gibson, M.; Court, J.; Schlossmacher, M.; Allsop, D. Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease. FASEB J. 2006, 20, 419-425.
-
(2006)
FASEB J
, vol.20
, pp. 419-425
-
-
El-Agnaf, O.1
Salem, S.2
Paleologou, K.3
Curran, M.4
Gibson, M.5
Court, J.6
Schlossmacher, M.7
Allsop, D.8
-
71
-
-
79251565507
-
Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity
-
Danzer, K.; Ruf, W.; Putcha, P.; Joyner, D.; Hashimoto, T.; Glabe, C.; Hyman, B.; McLean, P. Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity. FASEB J. 2011, 25, 326-336.
-
(2011)
FASEB J
, vol.25
, pp. 326-336
-
-
Danzer, K.1
Ruf, W.2
Putcha, P.3
Joyner, D.4
Hashimoto, T.5
Glabe, C.6
Hyman, B.7
McLean, P.8
-
72
-
-
84973304473
-
DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins
-
Fontaine, S.; Zheng, D.; Sabbagh, J.; Martin, M.; Chaput, D.; Darling, A.; Trotter, J.; Stothert, A.; Nordhues, B.; Lussier, A.; et al. DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins. EMBO J. 2016, 35, 1537-1549.
-
(2016)
EMBO J
, vol.35
, pp. 1537-1549
-
-
Fontaine, S.1
Zheng, D.2
Sabbagh, J.3
Martin, M.4
Chaput, D.5
Darling, A.6
Trotter, J.7
Stothert, A.8
Nordhues, B.9
Lussier, A.10
-
73
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi, H.; Ekström, K.; Bossios, A.; Sjöstrand, M.; Lee, J.; Lötvall, J. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 2007, 9, 654-659.
-
(2007)
Nat. Cell Biol
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekström, K.2
Bossios, A.3
Sjöstrand, M.4
Lee, J.5
Lötvall, J.6
-
74
-
-
69949117622
-
Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
-
Gibbings, D.; Ciaudo, C.; Erhardt, M.; Voinnet, O. Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat. Cell Biol. 2009, 11, 1143-1149.
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 1143-1149
-
-
Gibbings, D.1
Ciaudo, C.2
Erhardt, M.3
Voinnet, O.4
-
75
-
-
20744436655
-
Exosome-dependent Trafficking of HSP70: A novel secretory pathway for cellular stress proteins
-
Lancaster, G.; Febbraio, M. Exosome-dependent Trafficking of HSP70: A novel secretory pathway for cellular stress proteins. J. Biol. Chem. 2005, 280, 23349-23355.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 23349-23355
-
-
Lancaster, G.1
Febbraio, M.2
-
76
-
-
0026094139
-
Shedding of vesicular material from the cell surface of eukaryotic cells: Different cellular phenomena
-
Beaudoin, A.; Grondin, G. Shedding of vesicular material from the cell surface of eukaryotic cells: Different cellular phenomena. Biochim. Biophys. Acta Rev. Biomembr. 1991, 1071, 203-219.
-
(1991)
Biochim. Biophys. Acta Rev. Biomembr
, vol.1071
, pp. 203-219
-
-
Beaudoin, A.1
Grondin, G.2
-
77
-
-
0033767690
-
Exosome: From internal vesicle of the multivesicular body to intercellular signaling device
-
Denzer, K.; Kleijmeer, M.; Heijnen, H.; Stoorvogel, W.; Geuze, H. Exosome: From internal vesicle of the multivesicular body to intercellular signaling device. J. Cell Sci. 2000, 113, 3365-3374.
-
(2000)
J. Cell Sci
, vol.113
, pp. 3365-3374
-
-
Denzer, K.1
Kleijmeer, M.2
Heijnen, H.3
Stoorvogel, W.4
Geuze, H.5
-
78
-
-
79551542416
-
Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis
-
Fitzner, D.; Schnaars, M.; van Rossum, D.; Krishnamoorthy, G.; Dibaj, P.; Bakhti, M.; Regen, T.; Hanisch, U.; Simons, M. Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis. J. Cell Sci. 2011, 124, 447-458.
-
(2011)
J. Cell Sci
, vol.124
, pp. 447-458
-
-
Fitzner, D.1
Schnaars, M.2
Van Rossum, D.3
Krishnamoorthy, G.4
Dibaj, P.5
Bakhti, M.6
Regen, T.7
Hanisch, U.8
Simons, M.9
-
79
-
-
84886810676
-
Extracellular vesicles as mediators of neuron-glia communication
-
Frühbeis, C.; Fröhlich, D.; Kuo, W.; Krämer-Albers, E. Extracellular vesicles as mediators of neuron-glia communication. Front. Cell. Neurosci. 2013, 7, 182.
-
(2013)
Front. Cell. Neurosci
, vol.7
, pp. 182
-
-
Frühbeis, C.1
Fröhlich, D.2
Kuo, W.3
Krämer-Albers, E.4
-
80
-
-
84880950361
-
Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte-Neuron Communication
-
Frühbeis, C.; Fröhlich, D.; Kuo, W.; Amphornrat, J.; Thilemann, S.; Saab, A.; Kirchhoff, F.; Möbius, W.; Goebbels, S.; Nave, K.; et al. Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte-Neuron Communication. PLoS Biol. 2013, 11, e1001604.
-
(2013)
Plos Biol
, vol.11
-
-
Frühbeis, C.1
Fröhlich, D.2
Kuo, W.3
Amphornrat, J.4
Thilemann, S.5
Saab, A.6
Kirchhoff, F.7
Möbius, W.8
Goebbels, S.9
Nave, K.10
-
81
-
-
84903694914
-
Transcellular degradation of axonal mitochondria
-
Davis, C.; Kim, K.; Bushong, E.; Mills, E.; Boassa, D.; Shih, T.; Kinebuchi, M.; Phan, S.; Zhou, Y.; Bihlmeyer, N.; et al. Transcellular degradation of axonal mitochondria. Proc. Natl. Acad. Sci. USA 2014, 111, 9633-9638.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 9633-9638
-
-
Davis, C.1
Kim, K.2
Bushong, E.3
Mills, E.4
Boassa, D.5
Shih, T.6
Kinebuchi, M.7
Phan, S.8
Zhou, Y.9
Bihlmeyer, N.10
-
82
-
-
84982732315
-
Transfer of mitochondria from astrocytes to neurons after stroke
-
Hayakawa, K.; Esposito, E.; Wang, X.; Terasaki, Y.; Liu, Y.; Xing, C.; Ji, X.; Lo, E. Transfer of mitochondria from astrocytes to neurons after stroke. Nature 2016, 535, 551-555.
-
(2016)
Nature
, vol.535
, pp. 551-555
-
-
Hayakawa, K.1
Esposito, E.2
Wang, X.3
Terasaki, Y.4
Liu, Y.5
Xing, C.6
Ji, X.7
Lo, E.8
-
83
-
-
79251592263
-
Multivesicular bodies in neurons: Distribution, protein content, and trafficking functions
-
Von Bartheld, C.; Altick, A. Multivesicular bodies in neurons: Distribution, protein content, and trafficking functions. Prog. Neurobiol. 2011, 93, 313-340.
-
(2011)
Prog. Neurobiol
, vol.93
, pp. 313-340
-
-
Von Bartheld, C.1
Altick, A.2
-
84
-
-
84865307818
-
Exosomal cell-to-cell transmission of α synuclein oligomers
-
Danzer, K.; Kranich, L.; Ruf, W.; Cagsal-Getkin, O.; Winslow, A.; Zhu, L.; Vanderburg, C.; McLean, P. Exosomal cell-to-cell transmission of α synuclein oligomers. Mol. Neurodegener. 2012, 7, 42.
-
(2012)
Mol. Neurodegener
, vol.7
, pp. 42
-
-
Danzer, K.1
Kranich, L.2
Ruf, W.3
Cagsal-Getkin, O.4
Winslow, A.5
Zhu, L.6
Vanderburg, C.7
McLean, P.8
-
85
-
-
79954631518
-
Lysosomal dysfunction increases exosome-mediated α-synuclein release and transmission
-
Alvarez-Erviti, L.; Seow, Y.; Schapira, A.; Gardiner, C.; Sargent, I.; Wood, M.; Cooper, J. Lysosomal dysfunction increases exosome-mediated α-synuclein release and transmission. Neurobiol. Dis. 2011, 42, 360-367.
-
(2011)
Neurobiol. Dis
, vol.42
, pp. 360-367
-
-
Alvarez-Erviti, L.1
Seow, Y.2
Schapira, A.3
Gardiner, C.4
Sargent, I.5
Wood, M.6
Cooper, J.7
-
86
-
-
77952648551
-
Cell-Produced-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
-
Emmanouilidou, E.; Melachroinou, K.; Roumeliotis, T.; Garbis, S.; Ntzouni, M.; Margaritis, L.; Stefanis, L.; Vekrellis, K. Cell-Produced-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival. J. Neurosci. 2010, 30, 6838-6851.
-
(2010)
J. Neurosci
, vol.30
, pp. 6838-6851
-
-
Emmanouilidou, E.1
Melachroinou, K.2
Roumeliotis, T.3
Garbis, S.4
Ntzouni, M.5
Margaritis, L.6
Stefanis, L.7
Vekrellis, K.8
-
87
-
-
84906097556
-
Multifaceted effects of oligodendroglial exosomes on neurons: Impact on neuronal firing rate, signal transduction and gene regulation
-
Frohlich, D.; Kuo, W.; Fruhbeis, C.; Sun, J.; Zehendner, C.; Luhmann, H.; Pinto, S.; Toedling, J.; Trotter, J.; Kramer-Albers, E. Multifaceted effects of oligodendroglial exosomes on neurons: Impact on neuronal firing rate, signal transduction and gene regulation. Philos. Trans. R. Soc. B Biol. Sci. 2014, 369.
-
(2014)
Philos. Trans. R. Soc. B Biol. Sci
, vol.369
-
-
Frohlich, D.1
Kuo, W.2
Fruhbeis, C.3
Sun, J.4
Zehendner, C.5
Luhmann, H.6
Pinto, S.7
Toedling, J.8
Trotter, J.9
Kramer-Albers, E.10
-
88
-
-
84940874206
-
Accumulation of phosphorylated α-synuclein in subpial and periventricular astrocytes in multiple system atrophy of long duration
-
Nakamura, K.; Mori, F.; Kon, T.; Tanji, K.; Miki, Y.; Tomiyama, M.; Kurotaki, H.; Toyoshima, Y.; Kakita, A.; Takahashi, H.; et al. Accumulation of phosphorylated α-synuclein in subpial and periventricular astrocytes in multiple system atrophy of long duration. Neuropathology 2016, 36, 157-167.
-
(2016)
Neuropathology
, vol.36
, pp. 157-167
-
-
Nakamura, K.1
Mori, F.2
Kon, T.3
Tanji, K.4
Miki, Y.5
Tomiyama, M.6
Kurotaki, H.7
Toyoshima, Y.8
Kakita, A.9
Takahashi, H.10
-
89
-
-
34547727312
-
Development of α-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson’s disease
-
Braak, H.; Sastre, M.; Del Tredici, K. Development of α-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson’s disease. Acta Neuropathol. 2007, 114, 231-241.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 231-241
-
-
Braak, H.1
Sastre, M.2
Del Tredici, K.3
-
90
-
-
0038100348
-
α-Synuclein pathology affecting Bergmann glia of the cerebellum in patients with α-synucleinopathies
-
Piao, Y.; Mori, F.; Hayashi, S.; Tanji, K.; Yoshimoto, M.; Kakita, A.; Wakabayashi, K.; Takahashi, H. α-Synuclein pathology affecting Bergmann glia of the cerebellum in patients with α-synucleinopathies. Acta Neuropathol. 2003, 105, 403-409. [PubMed]
-
(2003)
Acta Neuropathol
, vol.105
, pp. 403-409
-
-
Piao, Y.1
Mori, F.2
Hayashi, S.3
Tanji, K.4
Yoshimoto, M.5
Kakita, A.6
Wakabayashi, K.7
Takahashi, H.8
-
91
-
-
84892538035
-
α-Synuclein transfers from neurons to oligodendrocytes
-
Reyes, J.; Rey, N.; Bousset, L.; Melki, R.; Brundin, P.; Angot, E. α-Synuclein transfers from neurons to oligodendrocytes. Glia 2013, 62, 387-398.
-
(2013)
Glia
, vol.62
, pp. 387-398
-
-
Reyes, J.1
Rey, N.2
Bousset, L.3
Melki, R.4
Brundin, P.5
Angot, E.6
-
92
-
-
69149089854
-
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein
-
Desplats, P.; Lee, H.; Bae, E.; Patrick, C.; Rockenstein, E.; Crews, L.; Spencer, B.; Masliah, E.; Lee, S. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein. Proc. Natl. Acad. Sci. USA 2009, 106, 13010-13015.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 13010-13015
-
-
Desplats, P.1
Lee, H.2
Bae, E.3
Patrick, C.4
Rockenstein, E.5
Crews, L.6
Spencer, B.7
Masliah, E.8
Lee, S.9
-
93
-
-
34948870903
-
Identification of Proteins Involved in Microglial Endocytosis of α-Synuclein
-
Liu, J.; Zhou, Y.; Wang, Y.; Fong, H.; Murray, T.; Zhang, J. Identification of Proteins Involved in Microglial Endocytosis of α-Synuclein. J. Proteome Res. 2007, 6, 3614-3627.
-
(2007)
J. Proteome Res
, vol.6
, pp. 3614-3627
-
-
Liu, J.1
Zhou, Y.2
Wang, Y.3
Fong, H.4
Murray, T.5
Zhang, J.6
-
94
-
-
44749083979
-
Assembly-dependent endocytosis and clearance of extracellular α-synuclein
-
Lee, H.; Suk, J.; Bae, E.; Lee, J.; Paik, S.; Lee, S. Assembly-dependent endocytosis and clearance of extracellular α-synuclein. Int. J. Biochem. Cell Biol. 2008, 40, 1835-1849.
-
(2008)
Int. J. Biochem. Cell Biol
, vol.40
, pp. 1835-1849
-
-
Lee, H.1
Suk, J.2
Bae, E.3
Lee, J.4
Paik, S.5
Lee, S.6
-
95
-
-
84864915936
-
Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: A potent therapeutic target for synucleinopathy
-
Konno, M.; Hasegawa, T.; Baba, T.; Miura, E.; Sugeno, N.; Kikuchi, A.; Fiesel, F.; Sasaki, T.; Aoki, M.; Itoyama, Y.; et al. Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: A potent therapeutic target for synucleinopathy. Mol. Neurodegener. 2012, 7, 38.
-
(2012)
Mol. Neurodegener
, vol.7
, pp. 38
-
-
Konno, M.1
Hasegawa, T.2
Baba, T.3
Miura, E.4
Sugeno, N.5
Kikuchi, A.6
Fiesel, F.7
Sasaki, T.8
Aoki, M.9
Itoyama, Y.10
-
96
-
-
84989172537
-
Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3
-
Mao, X.; Ou, M.; Karuppagounder, S.; Kam, T.; Yin, X.; Xiong, Y.; Ge, P.; Umanah, G.; Brahmachari, S.; Shin, J.; et al. Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3. Science 2016, 353.
-
(2016)
Science
, vol.353
-
-
Mao, X.1
Ou, M.2
Karuppagounder, S.3
Kam, T.4
Yin, X.5
Xiong, Y.6
Ge, P.7
Umanah, G.8
Brahmachari, S.9
Shin, J.10
-
97
-
-
0344813707
-
Characterization of a 76kDa endosomal, multispanning membrane protein that is highly conserved throughout evolution
-
Schimmöller, F.; Dıaz, E.; Mühlbauer, B.; Pfeffer, S. Characterization of a 76kDa endosomal, multispanning membrane protein that is highly conserved throughout evolution. Gene 1998, 216, 311-318.
-
(1998)
Gene
, vol.216
, pp. 311-318
-
-
Schimmöller, F.1
Dıaz, E.2
Mühlbauer, B.3
Pfeffer, S.4
-
98
-
-
84997552915
-
Rogue protein’s partners offer hope in Parkinson’s disease
-
Wadman, M. Rogue protein’s partners offer hope in Parkinson’s disease. Science 2016, 354, 956.
-
(2016)
Science
, vol.354
, pp. 956
-
-
Wadman, M.1
-
99
-
-
84858403126
-
Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, α-Synuclein Accumulation, and Neurotoxicity
-
Usenovic, M.; Tresse, E.; Mazzulli, J.; Taylor, J.; Krainc, D. Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, α-Synuclein Accumulation, and Neurotoxicity. J. Neurosci. 2012, 32, 4240-4246.
-
(2012)
J. Neurosci
, vol.32
, pp. 4240-4246
-
-
Usenovic, M.1
Tresse, E.2
Mazzulli, J.3
Taylor, J.4
Krainc, D.5
-
100
-
-
84899818136
-
Glucocerebrosidase is shaking up the synucleinopathies
-
Siebert, M.; Sidransky, E.; Westbroek, W. Glucocerebrosidase is shaking up the synucleinopathies. Brain 2014, 137, 1304-1322.
-
(2014)
Brain
, vol.137
, pp. 1304-1322
-
-
Siebert, M.1
Sidransky, E.2
Westbroek, W.3
-
101
-
-
84882306577
-
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
-
Holmes, B.; DeVos, S.; Kfoury, N.; Li, M.; Jacks, R.; Yanamandra, K.; Ouidja, M.; Brodsky, F.; Marasa, J.; Bagchi, D.; et al. Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds. Proc. Natl. Acad. Sci. USA 2013, 110, E3138-E3147.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. E3138-E3147
-
-
Holmes, B.1
Devos, S.2
Kfoury, N.3
Li, M.4
Jacks, R.5
Yanamandra, K.6
Ouidja, M.7
Brodsky, F.8
Marasa, J.9
Bagchi, D.10
-
102
-
-
84989908457
-
Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes
-
Abounit, S.; Bousset, L.; Loria, F.; Zhu, S.; de Chaumont, F.; Pieri, L.; Olivo-Marin, J.; Melki, R.; Zurzolo, C. Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes. EMBO J. 2016, 35, 2120-2138.
-
(2016)
EMBO J
, vol.35
, pp. 2120-2138
-
-
Abounit, S.1
Bousset, L.2
Loria, F.3
Zhu, S.4
De Chaumont, F.5
Pieri, L.6
Olivo-Marin, J.7
Melki, R.8
Zurzolo, C.9
-
103
-
-
84929129994
-
Extracellular-vesicle type of volume transmission and tunnelling-nanotube type of wiring transmission add a new dimension to brain neuro-glial networks
-
Agnati, L.; Fuxe, K. Extracellular-vesicle type of volume transmission and tunnelling-nanotube type of wiring transmission add a new dimension to brain neuro-glial networks. Philos. Trans. R. Soc. B Biol. Sci. 2014, 369.
-
(2014)
Philos. Trans. R. Soc. B Biol. Sci
, vol.369
-
-
Agnati, L.1
Fuxe, K.2
-
104
-
-
61849178720
-
Prions hijack tunnelling nanotubes for intercellular spread
-
Gousset, K.; Schiff, E.; Langevin, C.; Marijanovic, Z.; Caputo, A.; Browman, D.; Chenouard, N.; de Chaumont, F.; Martino, A.; Enninga, J.; et al. Prions hijack tunnelling nanotubes for intercellular spread. Nat. Cell Biol. 2009, 11, 328-336.
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 328-336
-
-
Gousset, K.1
Schiff, E.2
Langevin, C.3
Marijanovic, Z.4
Caputo, A.5
Browman, D.6
Chenouard, N.7
De Chaumont, F.8
Martino, A.9
Enninga, J.10
-
105
-
-
57249097160
-
Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking
-
Eugenin, E.; Gaskill, P.; Berman, J. Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking. Cell. Immunol. 2009, 254, 142-148.
-
(2009)
Cell. Immunol
, vol.254
, pp. 142-148
-
-
Eugenin, E.1
Gaskill, P.2
Berman, J.3
-
106
-
-
3242767507
-
Cutting Edge: Membrane Nanotubes Connect Immune Cells
-
Onfelt, B.; Nedvetzki, S.; Yanagi, K.; Davis, D. Cutting Edge: Membrane Nanotubes Connect Immune Cells. J. Immunol. 2004, 173, 1511-1513.
-
(2004)
J. Immunol
, vol.173
, pp. 1511-1513
-
-
Onfelt, B.1
Nedvetzki, S.2
Yanagi, K.3
Davis, D.4
-
107
-
-
33845421625
-
Structurally Distinct Membrane Nanotubes between Human Macrophages Support Long-Distance Vesicular Traffic or Surfing of Bacteria
-
Onfelt, B.; Nedvetzki, S.; Benninger, R.; Purbhoo, M.; Sowinski, S.; Hume, A.; Seabra, M.; Neil, M.; French, P.; Davis, D. Structurally Distinct Membrane Nanotubes between Human Macrophages Support Long-Distance Vesicular Traffic or Surfing of Bacteria. J. Immunol. 2006, 177, 8476-8483.
-
(2006)
J. Immunol
, vol.177
, pp. 8476-8483
-
-
Onfelt, B.1
Nedvetzki, S.2
Benninger, R.3
Purbhoo, M.4
Sowinski, S.5
Hume, A.6
Seabra, M.7
Neil, M.8
French, P.9
Davis, D.10
-
108
-
-
24944546733
-
Hydrogen peroxide alters membrane and cytoskeleton properties and increases intercellular connections in astrocytes
-
Zhu, D.; Tan, K.; Zhang, X.; Sun, A.; Sun, G.; Lee, J. Hydrogen peroxide alters membrane and cytoskeleton properties and increases intercellular connections in astrocytes. J. Cell Sci. 2005, 118, 3695-3703.
-
(2005)
J. Cell Sci
, vol.118
, pp. 3695-3703
-
-
Zhu, D.1
Tan, K.2
Zhang, X.3
Sun, A.4
Sun, G.5
Lee, J.6
-
109
-
-
1142286348
-
Nanotubular Highways for Intercellular Organelle Transport
-
Rustom, A.; Saffrich, R.; Markovic, I.; Walther, P.; Gerdes, H. Nanotubular Highways for Intercellular Organelle Transport. Science 2004, 303, 1007-1010.
-
(2004)
Science
, vol.303
, pp. 1007-1010
-
-
Rustom, A.1
Saffrich, R.2
Markovic, I.3
Walther, P.4
Gerdes, H.5
-
110
-
-
84871201559
-
Tunneling-nanotube direction determination in neurons and astrocytes
-
Sun, X.; Wang, Y.; Zhang, J.; Tu, J.; Wang, X.; Su, X.; Wang, L.; Zhang, Y. Tunneling-nanotube direction determination in neurons and astrocytes. Cell Death Dis. 2012, 3, e438.
-
(2012)
Cell Death Dis
, vol.3
-
-
Sun, X.1
Wang, Y.2
Zhang, J.3
Tu, J.4
Wang, X.5
Su, X.6
Wang, L.7
Zhang, Y.8
-
111
-
-
84952012402
-
Exosomes and nanotubes: Control of immune cell communication
-
McCoy-Simandle, K.; Hanna, S.; Cox, D. Exosomes and nanotubes: Control of immune cell communication. Int. J. Biochem. Cell Biol. 2016, 71, 44-54.
-
(2016)
Int. J. Biochem. Cell Biol
, vol.71
, pp. 44-54
-
-
McCoy-Simandle, K.1
Hanna, S.2
Cox, D.3
-
112
-
-
79955605102
-
Physiology of Microglia
-
Kettenmann, H.; Hanisch, U.; Noda, M.; Verkhratsky, A. Physiology of Microglia. Physiol. Rev. 2011, 91, 461-553.
-
(2011)
Physiol. Rev
, vol.91
, pp. 461-553
-
-
Kettenmann, H.1
Hanisch, U.2
Noda, M.3
Verkhratsky, A.4
-
113
-
-
84857406614
-
The Spider Effect: Morphological and Orienting Classification of Microglia in Response to Stimuli in Vivo
-
Jonas, R.; Yuan, T.; Liang, Y.; Jonas, J.; Tay, D.; Ellis-Behnke, R. The Spider Effect: Morphological and Orienting Classification of Microglia in Response to Stimuli in Vivo. PLoS ONE 2012, 7, e30763.
-
(2012)
Plos ONE
, vol.7
-
-
Jonas, R.1
Yuan, T.2
Liang, Y.3
Jonas, J.4
Tay, D.5
Ellis-Behnke, R.6
-
114
-
-
33846585119
-
Systemic infections and inflammation affect chronic neurodegeneration
-
Perry, V.; Cunningham, C.; Holmes, C. Systemic infections and inflammation affect chronic neurodegeneration. Nat. Rev. Immunol. 2007, 7, 161-167.
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 161-167
-
-
Perry, V.1
Cunningham, C.2
Holmes, C.3
-
115
-
-
60149098421
-
Debris clearance by microglia: An essential link between degeneration and regeneration
-
Neumann, H.; Kotter, M.; Franklin, R. Debris clearance by microglia: An essential link between degeneration and regeneration. Brain 2008, 132, 288-295.
-
(2008)
Brain
, vol.132
, pp. 288-295
-
-
Neumann, H.1
Kotter, M.2
Franklin, R.3
-
116
-
-
84891836634
-
The Role of Glia in α-Synucleinopathies
-
Fellner, L.; Stefanova, N. The Role of Glia in α-Synucleinopathies. Mol. Neurobiol. 2012, 47, 575-586.
-
(2012)
Mol. Neurobiol
, vol.47
, pp. 575-586
-
-
Fellner, L.1
Stefanova, N.2
-
117
-
-
84866030054
-
Imaging of microglia in patients with neurodegenerative disorders
-
Politis, M.; Su, P.; Piccini, P. Imaging of microglia in patients with neurodegenerative disorders. Front. Pharmacol. 2012, 3.
-
(2012)
Front. Pharmacol
, vol.3
-
-
Politis, M.1
Su, P.2
Piccini, P.3
-
118
-
-
84876530516
-
Proinflammatory Cytokines Are Elevated in Serum of Patients with Multiple System Atrophy
-
Kaufman, E.; Hall, S.; Surova, Y.; Widner, H.; Hansson, O.; Lindqvist, D. Proinflammatory Cytokines Are Elevated in Serum of Patients with Multiple System Atrophy. PLoS ONE 2013, 8, e62354.
-
(2013)
Plos ONE
, vol.8
-
-
Kaufman, E.1
Hall, S.2
Surova, Y.3
Widner, H.4
Hansson, O.5
Lindqvist, D.6
-
119
-
-
84938599006
-
When DLB, PD, and PSP masquerade as MSA
-
Koga, S.; Aoki, N.; Uitti, R.; van Gerpen, J.; Cheshire, W.; Josephs, K.; Wszolek, Z.; Langston, J.; Dickson, D. When DLB, PD, and PSP masquerade as MSA. Neurology 2015, 85, 404-412.
-
(2015)
Neurology
, vol.85
, pp. 404-412
-
-
Koga, S.1
Aoki, N.2
Uitti, R.3
Van Gerpen, J.4
Cheshire, W.5
Josephs, K.6
Wszolek, Z.7
Langston, J.8
Dickson, D.9
-
120
-
-
14744296610
-
Inflammatory Process in Parkinsons Disease: Role for Cytokines
-
Nagatsu, T.; Sawada, M. Inflammatory Process in Parkinsons Disease: Role for Cytokines. Curr. Pharm. Des. 2005, 11, 999-1016.
-
(2005)
Curr. Pharm. Des
, vol.11
, pp. 999-1016
-
-
Nagatsu, T.1
Sawada, M.2
-
121
-
-
84863892112
-
Inflammation in Parkinson’s Disease
-
Tufekci, K.; Meuwissen, R.; Genc, S.; Genc, K. Inflammation in Parkinson’s Disease. Adv. Protein Chem. Struct. Biol. 2012, 88, 69-132.
-
(2012)
Adv. Protein Chem. Struct. Biol
, vol.88
, pp. 69-132
-
-
Tufekci, K.1
Meuwissen, R.2
Genc, S.3
Genc, K.4
-
122
-
-
0034090258
-
Glucose Hypometabolism and Neuropathological Correlates in Brains of Dementia with Lewy Bodies
-
Higuchi, M.; Tashiro, M.; Arai, H.; Okamura, N.; Hara, S.; Higuchi, S.; Itoh, M.; Shin, R.; Trojanowski, J.; Sasaki, H. Glucose Hypometabolism and Neuropathological Correlates in Brains of Dementia with Lewy Bodies. Exp. Neurol. 2000, 162, 247-256.
-
(2000)
Exp. Neurol
, vol.162
, pp. 247-256
-
-
Higuchi, M.1
Tashiro, M.2
Arai, H.3
Okamura, N.4
Hara, S.5
Higuchi, S.6
Itoh, M.7
Shin, R.8
Trojanowski, J.9
Sasaki, H.10
-
123
-
-
68149123529
-
Alterations in lysosomal and proteasomal markers in Parkinson’s disease: Relationship to α-synuclein inclusions
-
Chu, Y.; Dodiya, H.; Aebischer, P.; Olanow, C.; Kordower, J. Alterations in lysosomal and proteasomal markers in Parkinson’s disease: Relationship to α-synuclein inclusions. Neurobiol. Dis. 2009, 35, 385-398.
-
(2009)
Neurobiol. Dis
, vol.35
, pp. 385-398
-
-
Chu, Y.1
Dodiya, H.2
Aebischer, P.3
Olanow, C.4
Kordower, J.5
-
124
-
-
20444413356
-
Effects of α-synuclein immunization in a mouse model of Parkinson’s disease
-
Masliah, E.; Rockenstein, E.; Adame, A.; Alford, M.; Crews, L.; Hashimoto, M.; Seubert, P.; Lee, M.; Goldstein, J.; Chilicote, T.; et al. Effects of α-synuclein immunization in a mouse model of Parkinson’s disease. Neuron 2005, 46, 857-868.
-
(2005)
Neuron
, vol.46
, pp. 857-868
-
-
Masliah, E.1
Rockenstein, E.2
Adame, A.3
Alford, M.4
Crews, L.5
Hashimoto, M.6
Seubert, P.7
Lee, M.8
Goldstein, J.9
Chilicote, T.10
-
125
-
-
67449123312
-
On the mechanism of internalization of α-synuclein into microglia: Roles of ganglioside GM1 and lipid raft
-
Park, J.; Kim, K.; Lee, S.; Ryu, J.; Chung, K.; Choo, Y.; Jou, I.; Kim, J.; Park, S. On the mechanism of internalization of α-synuclein into microglia: Roles of ganglioside GM1 and lipid raft. J. Neurochem. 2009, 110, 400-411.
-
(2009)
J. Neurochem
, vol.110
, pp. 400-411
-
-
Park, J.1
Kim, K.2
Lee, S.3
Ryu, J.4
Chung, K.5
Choo, Y.6
Jou, I.7
Kim, J.8
Park, S.9
-
126
-
-
3342951965
-
Lipid Rafts Mediate the Synaptic Localization of α-Synuclein
-
Fortin, D.; Troyer, M.; Nakamura, K.; Kubo, S.; Anthony, M.; Edwards, R. Lipid Rafts Mediate the Synaptic Localization of α-Synuclein. J. Neurosci. 2004, 24, 6715-6723.
-
(2004)
J. Neurosci
, vol.24
, pp. 6715-6723
-
-
Fortin, D.1
Troyer, M.2
Nakamura, K.3
Kubo, S.4
Anthony, M.5
Edwards, R.6
-
127
-
-
43549104227
-
Statins reduce neuronal α-synuclein aggregation in in vitro models of Parkinson’s disease
-
Bar-On, P.; Crews, L.; Koob, A.; Mizuno, H.; Adame, A.; Spencer, B.; Masliah, E. Statins reduce neuronal α-synuclein aggregation in in vitro models of Parkinson’s disease. J. Neurochem. 2008, 105, 1656-1667.
-
(2008)
J. Neurochem
, vol.105
, pp. 1656-1667
-
-
Bar-On, P.1
Crews, L.2
Koob, A.3
Mizuno, H.4
Adame, A.5
Spencer, B.6
Masliah, E.7
-
128
-
-
24744432079
-
A Combinatorial Code for the Interaction of α-Synuclein with Membranes
-
Kubo, S.; Nemani, V.; Chalkley, R.; Anthony, M.; Hattori, N.; Mizuno, Y.; Edwards, R.; Fortin, D. A Combinatorial Code for the Interaction of α-Synuclein with Membranes. J. Biol. Chem. 2005, 280, 31664-31672.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 31664-31672
-
-
Kubo, S.1
Nemani, V.2
Chalkley, R.3
Anthony, M.4
Hattori, N.5
Mizuno, Y.6
Edwards, R.7
Fortin, D.8
-
129
-
-
84928005022
-
2 -dependent Lyn phosphorylation
-
2 -dependent Lyn phosphorylation. Proc. Natl. Acad. Sci. USA 2015, 112, E1926-E1935.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. E1926-E1935
-
-
Wang, S.1
Chu, C.2
Stewart, T.3
Ginghina, C.4
Wang, Y.5
Nie, H.6
Guo, M.7
Wilson, B.8
Hong, J.9
Zhang, J.10
-
130
-
-
51449099473
-
Synuclein activates microglia in a model of Parkinson’s disease
-
Su, X.; Maguire-Zeiss, K.; Giuliano, R.; Prifti, L.; Venkatesh, K.; Federoff, H. Synuclein activates microglia in a model of Parkinson’s disease. Neurobiol. Aging 2008, 29, 1690-1701.
-
(2008)
Neurobiol. Aging
, vol.29
, pp. 1690-1701
-
-
Su, X.1
Maguire-Zeiss, K.2
Giuliano, R.3
Prifti, L.4
Venkatesh, K.5
Federoff, H.6
-
131
-
-
80052473816
-
Toll-Like Receptor 4 Promotes α-Synuclein Clearance and Survival of Nigral Dopaminergic Neurons
-
Stefanova, N.; Fellner, L.; Reindl, M.; Masliah, E.; Poewe, W.; Wenning, G. Toll-Like Receptor 4 Promotes α-Synuclein Clearance and Survival of Nigral Dopaminergic Neurons. Am. J. Pathol. 2011, 179, 954-963.
-
(2011)
Am. J. Pathol
, vol.179
, pp. 954-963
-
-
Stefanova, N.1
Fellner, L.2
Reindl, M.3
Masliah, E.4
Poewe, W.5
Wenning, G.6
-
132
-
-
84875898265
-
Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia
-
Kim, C.; Ho, D.; Suk, J.; You, S.; Michael, S.; Kang, J.; Joong Lee, S.; Masliah, E.; Hwang, D.; Lee, H.; et al. Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia. Nat. Commun. 2013, 4, 1562.
-
(2013)
Nat. Commun
, vol.4
, pp. 1562
-
-
Kim, C.1
Ho, D.2
Suk, J.3
You, S.4
Michael, S.5
Kang, J.6
Joong Lee, S.7
Masliah, E.8
Hwang, D.9
Lee, H.10
-
133
-
-
84893372929
-
Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
-
Roodveldt, C.; Labrador-Garrido, A.; Gonzalez-Rey, E.; Lachaud, C.; Guilliams, T.; Fernandez-Montesinos, R.; Benitez-Rondan, A.; Robledo, G.; Hmadcha, A.; Delgado, M.; et al. Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation. PLoS ONE 2013, 8, e79160.
-
(2013)
Plos ONE
, vol.8
-
-
Roodveldt, C.1
Labrador-Garrido, A.2
Gonzalez-Rey, E.3
Lachaud, C.4
Guilliams, T.5
Fernandez-Montesinos, R.6
Benitez-Rondan, A.7
Robledo, G.8
Hmadcha, A.9
Delgado, M.10
-
134
-
-
84872595532
-
Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
-
Fellner, L.; Irschick, R.; Schanda, K.; Reindl, M.; Klimaschewski, L.; Poewe, W.; Wenning, G.; Stefanova, N. Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia. Glia 2013, 61, 349-360.
-
(2013)
Glia
, vol.61
, pp. 349-360
-
-
Fellner, L.1
Irschick, R.2
Schanda, K.3
Reindl, M.4
Klimaschewski, L.5
Poewe, W.6
Wenning, G.7
Stefanova, N.8
-
135
-
-
84958106930
-
Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases
-
Tang, Y.; Le, W. Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases. Mol. Neurobiol. 2015, 53, 1181-1194.
-
(2015)
Mol. Neurobiol
, vol.53
, pp. 1181-1194
-
-
Tang, Y.1
Le, W.2
-
136
-
-
84945474523
-
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
-
Asai, H.; Ikezu, S.; Tsunoda, S.; Medalla, M.; Luebke, J.; Haydar, T.; Wolozin, B.; Butovsky, O.; Kügler, S.; Ikezu, T. Depletion of microglia and inhibition of exosome synthesis halt tau propagation. Nat. Neurosci. 2015, 18, 1584-1593.
-
(2015)
Nat. Neurosci
, vol.18
, pp. 1584-1593
-
-
Asai, H.1
Ikezu, S.2
Tsunoda, S.3
Medalla, M.4
Luebke, J.5
Haydar, T.6
Wolozin, B.7
Butovsky, O.8
Kügler, S.9
Ikezu, T.10
-
137
-
-
84947587748
-
Neuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein Aggregation
-
Vieira, B.D.; Radford, R.A.; Chung, R.S.; Guillemin, G.J.; Pountney, D.L. Neuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein Aggregation. Front. Cell Neurosci. 2015, 9, 437.
-
(2015)
Front. Cell Neurosci
, vol.9
, pp. 437
-
-
Vieira, B.D.1
Radford, R.A.2
Chung, R.S.3
Guillemin, G.J.4
Pountney, D.L.5
-
138
-
-
84949316085
-
The Glymphatic System: A Beginner’s Guide
-
Jessen, N.; Munk, A.; Lundgaard, I.; Nedergaard, M. The Glymphatic System: A Beginner’s Guide. Neurochem. Res. 2015, 40, 2583-2599.
-
(2015)
Neurochem. Res
, vol.40
, pp. 2583-2599
-
-
Jessen, N.1
Munk, A.2
Lundgaard, I.3
Nedergaard, M.4
-
139
-
-
84865123660
-
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
-
Iliff, J.; Wang, M.; Liao, Y.; Plogg, B.; Peng, W.; Gundersen, G.; Benveniste, H.; Vates, G.; Deane, R.; Goldman, S.; et al. A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β. Sci. Transl. Med. 2012, 4.
-
(2012)
Sci. Transl. Med
, vol.4
-
-
Iliff, J.1
Wang, M.2
Liao, Y.3
Plogg, B.4
Peng, W.5
Gundersen, G.6
Benveniste, H.7
Vates, G.8
Deane, R.9
Goldman, S.10
-
140
-
-
84914691722
-
Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury
-
Iliff, J.; Chen, M.; Plog, B.; Zeppenfeld, D.; Soltero, M.; Yang, L.; Singh, I.; Deane, R.; Nedergaard, M. Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury. J. Neurosci. 2014, 34, 16180-16193.
-
(2014)
J. Neurosci
, vol.34
, pp. 16180-16193
-
-
Iliff, J.1
Chen, M.2
Plog, B.3
Zeppenfeld, D.4
Soltero, M.5
Yang, L.6
Singh, I.7
Deane, R.8
Nedergaard, M.9
-
141
-
-
85013631378
-
Expression of aquaporin 1 and aquaporin 4 in the temporal neocortex of patients with Parkinson’s disease
-
Hoshi, A.; Tsunoda, A.; Tada, M.; Nishizawa, M.; Ugawa, Y.; Kakita, A. Expression of aquaporin 1 and aquaporin 4 in the temporal neocortex of patients with Parkinson’s disease. Brain Pathol. 2016.
-
(2016)
Brain Pathol
-
-
Hoshi, A.1
Tsunoda, A.2
Tada, M.3
Nishizawa, M.4
Ugawa, Y.5
Kakita, A.6
-
142
-
-
84939232612
-
Cerebrospinal fluid α-synuclein as a biomarker for Parkinson’s disease diagnosis: A systematic review and meta-analysis
-
Gao, L.; Tang, H.; Nie, K.; Wang, L.; Zhao, J.; Gan, R.; Huang, J.; Zhu, R.; Feng, S.; Duan, Z.; et al. Cerebrospinal fluid α-synuclein as a biomarker for Parkinson’s disease diagnosis: A systematic review and meta-analysis. Int. J. Neurosci. 2014, 125, 645-654.
-
(2014)
Int. J. Neurosci
, vol.125
, pp. 645-654
-
-
Gao, L.1
Tang, H.2
Nie, K.3
Wang, L.4
Zhao, J.5
Gan, R.6
Huang, J.7
Zhu, R.8
Feng, S.9
Duan, Z.10
-
143
-
-
84992711364
-
Glymphatic clearance controls state-dependent changes in brain lactate concentration
-
Lundgaard, I.; Lu, M.; Yang, E.; Peng, W.; Mestre, H.; Hitomi, E.; Deane, R.; Nedergaard, M. Glymphatic clearance controls state-dependent changes in brain lactate concentration. J. Cereb. Blood Flow Metab. 2016.
-
(2016)
J. Cereb. Blood Flow Metab
-
-
Lundgaard, I.1
Lu, M.2
Yang, E.3
Peng, W.4
Mestre, H.5
Hitomi, E.6
Deane, R.7
Nedergaard, M.8
|