-
1
-
-
0042837887
-
A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
-
Olanow CW, Goetz CG, Kordower JH, Stoessl AJ, Sossi V, Brin MF, Shannon KM, Nauert GM, Perl DP, Godbold J and Freeman TB. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann Neurol 2003; 54: 403-414.
-
(2003)
Ann Neurol
, vol.54
, pp. 403-414
-
-
Olanow, C.W.1
Goetz, C.G.2
Kordower, J.H.3
Stoessl, A.J.4
Sossi, V.5
Brin, M.F.6
Shannon, K.M.7
Nauert, G.M.8
Perl, D.P.9
Godbold, J.10
Freeman, T.B.11
-
2
-
-
0035826089
-
Transplantation of embryonic dopamine neurons for severe Parkinson's disease
-
Freed CR, Greene PE, Breeze RE, Tsai WY, DuMouchel W, Kao R, Dillon S, Winfield H, Culver S, Trojanowski JQ, Eidelberg D and Fahn S. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med 2001; 344: 710-719.
-
(2001)
N Engl J Med
, vol.344
, pp. 710-719
-
-
Freed, C.R.1
Greene, P.E.2
Breeze, R.E.3
Tsai, W.Y.4
DuMouchel, W.5
Kao, R.6
Dillon, S.7
Winfield, H.8
Culver, S.9
Trojanowski, J.Q.10
Eidelberg, D.11
Fahn, S.12
-
3
-
-
43249114934
-
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
-
Kordower JH, Chu Y, Hauser RA, Freeman TB and Olanow CW. Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat Med 2008; 14: 504-506.
-
(2008)
Nat Med
, vol.14
, pp. 504-506
-
-
Kordower, J.H.1
Chu, Y.2
Hauser, R.A.3
Freeman, T.B.4
Olanow, C.W.5
-
4
-
-
61449216234
-
Transplanted dopaminergic neurons develop PD pathologic changes: A second case report
-
Kordower JH, Chu Y, Hauser RA, Olanow CW and Freeman TB. Transplanted dopaminergic neurons develop PD pathologic changes: a second case report. Mov Disord 2008; 23: 2303-2306.
-
(2008)
Mov Disord
, vol.23
, pp. 2303-2306
-
-
Kordower, J.H.1
Chu, Y.2
Hauser, R.A.3
Olanow, C.W.4
Freeman, T.B.5
-
5
-
-
43249110200
-
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest hostto-graft disease propagation
-
Li JY, Englund E, Holton JL, Soulet D, Hagell P, Lees AJ, Lashley T, Quinn NP, Rehncrona S, Bjorklund A, Widner H, Revesz T, Lindvall O and Brundin P. Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest hostto-graft disease propagation. Nat Med 2008; 14: 501-503.
-
(2008)
Nat Med
, vol.14
, pp. 501-503
-
-
Li, J.Y.1
Englund, E.2
Holton, J.L.3
Soulet, D.4
Hagell, P.5
Lees, A.J.6
Lashley, T.7
Quinn, N.P.8
Rehncrona, S.9
Bjorklund, A.10
Widner, H.11
Revesz, T.12
Lindvall, O.13
Brundin, P.14
-
6
-
-
77949906891
-
Lewy body pathology in fetal grafts
-
Chu Y and Kordower JH. Lewy body pathology in fetal grafts. Ann N Y Acad Sci 2010; 1184: 55-67.
-
(2010)
Ann N Y Acad Sci
, vol.1184
, pp. 55-67
-
-
Chu, Y.1
Kordower, J.H.2
-
7
-
-
69149089854
-
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein
-
Desplats P, Lee HJ, Bae EJ, Patrick C, Rockenstein E, Crews L, Spencer B, Masliah E and Lee SJ. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc Natl Acad Sci U S A 2009; 106: 13010-13015.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13010-13015
-
-
Desplats, P.1
Lee, H.J.2
Bae, E.J.3
Patrick, C.4
Rockenstein, E.5
Crews, L.6
Spencer, B.7
Masliah, E.8
Lee, S.J.9
-
8
-
-
43249085326
-
Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years
-
Mendez I, Vinuela A, Astradsson A, Mukhida K, Hallett P, Robertson H, Tierney T, Holness R, Dagher A, Trojanowski JQ and Isacson O. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nat Med 2008; 14: 507-509.
-
(2008)
Nat Med
, vol.14
, pp. 507-509
-
-
Mendez, I.1
Vinuela, A.2
Astradsson, A.3
Mukhida, K.4
Hallett, P.5
Robertson, H.6
Tierney, T.7
Holness, R.8
Dagher, A.9
Trojanowski, J.Q.10
Isacson, O.11
-
9
-
-
69549113043
-
Lack of functional relevance of isolated cell damage in transplants of Parkinson's disease patients
-
Cooper O, Astradsson A, Hallett P, Robertson H, Mendez I and Isacson O. Lack of functional relevance of isolated cell damage in transplants of Parkinson's disease patients. J Neurol 2009; 256 Suppl 3: 310-316.
-
(2009)
J Neurol
, vol.256
, Issue.SUPPL. 3
, pp. 310-316
-
-
Cooper, O.1
Astradsson, A.2
Hallett, P.3
Robertson, H.4
Mendez, I.5
Isacson, O.6
-
10
-
-
52449117926
-
Research in motion: The enigma of Parkinson's disease pathology spread
-
Brundin P, Li JY, Holton JL, Lindvall O and Revesz T. Research in motion: the enigma of Parkinson's disease pathology spread. Nat Rev Neurosci 2008; 9: 741-745.
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 741-745
-
-
Brundin, P.1
Li, J.Y.2
Holton, J.L.3
Lindvall, O.4
Revesz, T.5
-
11
-
-
43249090937
-
Assessing fetal nerve cell grafts in Parkinson's disease
-
Braak H and Del Tredici K. Assessing fetal nerve cell grafts in Parkinson's disease. Nat Med 2008; 14: 483-485.
-
(2008)
Nat Med
, vol.14
, pp. 483-485
-
-
Braak, H.1
Del Tredici, K.2
-
12
-
-
0034069848
-
Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p
-
Gwinn-Hardy K, Mehta ND, Farrer M, Maraganore D, Muenter M, Yen SH, Hardy J and Dickson DW. Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p. Acta Neuropathol 2000; 99: 663-672.
-
(2000)
Acta Neuropathol
, vol.99
, pp. 663-672
-
-
Gwinn-Hardy, K.1
Mehta, N.D.2
Farrer, M.3
Maraganore, D.4
Muenter, M.5
Yen, S.H.6
Hardy, J.7
Dickson, D.W.8
-
13
-
-
0025278909
-
Ubiquitin immunoreac tive structures in normal human brains. Distribution and developmental aspects
-
Dickson DW, Wertkin A, Kress Y, Ksiezak-Reding H and Yen SH. Ubiquitin immunoreac tive structures in normal human brains. Distribution and developmental aspects. Lab Invest 1990; 63: 87-99.
-
(1990)
Lab Invest
, vol.63
, pp. 87-99
-
-
Dickson, D.W.1
Wertkin, A.2
Kress, Y.3
Ksiezak-Reding, H.4
Yen, S.H.5
-
14
-
-
71849092190
-
Neuropathological assessment of Parkinson's disease: Refining the diagnostic criteria
-
Dickson DW, Braak H, Duda JE, Duyckaerts C, Gasser T, Halliday GM, Hardy J, Leverenz JB, Del Tredici K, Wszolek ZK and Litvan I. Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. Lancet Neurol 2009; 8: 1150-1157.
-
(2009)
Lancet Neurol
, vol.8
, pp. 1150-1157
-
-
Dickson, D.W.1
Braak, H.2
Duda, J.E.3
Duyckaerts, C.4
Gasser, T.5
Halliday, G.M.6
Hardy, J.7
Leverenz, J.B.8
Del Tredici, K.9
Wszolek, Z.K.10
Litvan, I.11
-
15
-
-
27344438938
-
Microglial inflammation in the parkinsonian substantia nigra: Relationship to alpha-synuclein deposition
-
Croisier E, Moran LB, Dexter DT, Pearce RK and Graeber MB. Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition. J Neuroinflammation 2005; 2: 14.
-
(2005)
J Neuroinflammation
, vol.2
, pp. 14
-
-
Croisier, E.1
Moran, L.B.2
Dexter, D.T.3
Pearce, R.K.4
Graeber, M.B.5
-
16
-
-
0036315240
-
Demonstration of alphasynuclein immunoreactivity in neuronal and glial cytoplasm in normal human brain tissue using proteinase K and formic acid pretreatment
-
Mori F, Tanji K, Yoshimoto M, Takahashi H and Wakabayashi K. Demonstration of alphasynuclein immunoreactivity in neuronal and glial cytoplasm in normal human brain tissue using proteinase K and formic acid pretreatment. Exp Neurol 2002; 176: 98-104.
-
(2002)
Exp Neurol
, vol.176
, pp. 98-104
-
-
Mori, F.1
Tanji, K.2
Yoshimoto, M.3
Takahashi, H.4
Wakabayashi, K.5
-
17
-
-
34547727312
-
Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease
-
Braak H, Sastre M and Del Tredici K. Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease. Acta Neuropathol 2007; 114: 231-241.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 231-241
-
-
Braak, H.1
Sastre, M.2
Del Tredici, K.3
-
18
-
-
0035800223
-
Expression of alpha-synuclein in a human glioma cell line and its up-regulation by interleukin-1beta
-
Tanji K, Imaizumi T, Yoshida H, Mori F, Yoshimoto M, Satoh K and Wakabayashi K. Expression of alpha-synuclein in a human glioma cell line and its up-regulation by interleukin-1beta. Neuroreport 2001; 12: 1909-1912.
-
(2001)
Neuroreport
, vol.12
, pp. 1909-1912
-
-
Tanji, K.1
Imaizumi, T.2
Yoshida, H.3
Mori, F.4
Yoshimoto, M.5
Satoh, K.6
Wakabayashi, K.7
-
19
-
-
79551519276
-
Alpha-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
-
Hansen C, Angot E, Bergstrom AL, Steiner JA, Pieri L, Paul G, Outeiro TF, Melki R, Kallunki P, Fog K, Li JY and Brundin P. alpha-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. J Clin Invest 2011; 121: 715-725.
-
(2011)
J Clin Invest
, vol.121
, pp. 715-725
-
-
Hansen, C.1
Angot, E.2
Bergstrom, A.L.3
Steiner, J.A.4
Pieri, L.5
Paul, G.6
Outeiro, T.F.7
Melki, R.8
Kallunki, P.9
Fog, K.10
Li, J.Y.11
Brundin, P.12
-
20
-
-
77951885732
-
Non-classical exocytosis of alphasynuclein is sensitive to folding states and promoted under stress conditions
-
Jang A, Lee HJ, Suk JE, Jung JW, Kim KP and Lee SJ. Non-classical exocytosis of alphasynuclein is sensitive to folding states and promoted under stress conditions. J Neurochem 2010; 113: 1263-1274.
-
(2010)
J Neurochem
, vol.113
, pp. 1263-1274
-
-
Jang, A.1
Lee, H.J.2
Suk, J.E.3
Jung, J.W.4
Kim, K.P.5
Lee, S.J.6
-
21
-
-
40749094842
-
Origins and effects of extracellular alpha-synuclein: Implications in Parkinson's disease
-
Lee SJ. Origins and effects of extracellular alpha-synuclein: implications in Parkinson's disease. J Mol Neurosci 2008; 34: 17-22.
-
(2008)
J Mol Neurosci
, vol.34
, pp. 17-22
-
-
Lee, S.J.1
-
22
-
-
21344456506
-
Intravesicular localization and exocytosis of alpha-synuclein and its aggregates
-
Lee HJ, Patel S and Lee SJ. Intravesicular localization and exocytosis of alpha-synuclein and its aggregates. J Neurosci 2005; 25: 6016-6024.
-
(2005)
J Neurosci
, vol.25
, pp. 6016-6024
-
-
Lee, H.J.1
Patel, S.2
Lee, S.J.3
-
23
-
-
79251565507
-
Heat-shock protein 70 modulates toxic extracellular alpha-synuclein oligomers and rescues trans-synaptic toxicity
-
Danzer KM, Ruf WP, Putcha P, Joyner D, Hashimoto T, Glabe C, Hyman BT and McLean PJ. Heat-shock protein 70 modulates toxic extracellular alpha-synuclein oligomers and rescues trans-synaptic toxicity. FASEB J 2011; 25: 326-336.
-
(2011)
FASEB J
, vol.25
, pp. 326-336
-
-
Danzer, K.M.1
Ruf, W.P.2
Putcha, P.3
Joyner, D.4
Hashimoto, T.5
Glabe, C.6
Hyman, B.T.7
McLean, P.J.8
-
24
-
-
79951499176
-
Glia: Initiators and progressors of pathology in Parkinson's disease
-
Halliday GM and Stevens CH. Glia: initiators and progressors of pathology in Parkinson's disease. Mov Disord 2011; 26: 6-17.
-
(2011)
Mov Disord
, vol.26
, pp. 6-17
-
-
Halliday, G.M.1
Stevens, C.H.2
-
25
-
-
68149168120
-
Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration
-
Cicchetti F, Saporta S, Hauser RA, Parent M, Saint-Pierre M, Sanberg PR, Li XJ, Parker JR, Chu Y, Mufson EJ, Kordower JH and Freeman TB. Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration. Proc Natl Acad Sci U S A 2009; 106: 12483-12488.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12483-12488
-
-
Cicchetti, F.1
Saporta, S.2
Hauser, R.A.3
Parent, M.4
Saint-Pierre, M.5
Sanberg, P.R.6
Li, X.J.7
Parker, J.R.8
Chu, Y.9
Mufson, E.J.10
Kordower, J.H.11
Freeman, T.B.12
-
26
-
-
70349728587
-
Pathologic findings in retinal pigment epithelial cell implantation for Parkinson disease
-
Farag ES, Vinters HV and Bronstein J. Pathologic findings in retinal pigment epithelial cell implantation for Parkinson disease. Neurology 2009; 73: 1095-1102.
-
(2009)
Neurology
, vol.73
, pp. 1095-1102
-
-
Farag, E.S.1
Vinters, H.V.2
Bronstein, J.3
|