-
1
-
-
84861361400
-
Wiring through tunneling nanotubes–from electrical signals to organelle transfer
-
Abounit S, Zurzolo C (2012) Wiring through tunneling nanotubes–from electrical signals to organelle transfer. J Cell Sci 125: 1089–1098
-
(2012)
J Cell Sci
, vol.125
, pp. 1089-1098
-
-
Abounit, S.1
Zurzolo, C.2
-
2
-
-
84948819029
-
Intercellular communication in malignant pleural mesothelioma: properties of tunneling nanotubes
-
Ady JW, Desir S, Thayanithy V, Vogel RI, Moreira AL, Downey RJ, Fong Y, Manova-Todorova K, Moore MAS, Lou E (2014) Intercellular communication in malignant pleural mesothelioma: properties of tunneling nanotubes. Front Physiol 5: 400
-
(2014)
Front Physiol
, vol.5
, pp. 400
-
-
Ady, J.W.1
Desir, S.2
Thayanithy, V.3
Vogel, R.I.4
Moreira, A.L.5
Downey, R.J.6
Fong, Y.7
Manova-Todorova, K.8
Moore, M.A.S.9
Lou, E.10
-
3
-
-
79954631518
-
Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission
-
Alvarez-Erviti L, Seow Y, Schapira AH, Gardiner C, Sargent IL, Wood MJA, Cooper JM (2011) Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission. Neurobiol Dis 42: 360–367
-
(2011)
Neurobiol Dis
, vol.42
, pp. 360-367
-
-
Alvarez-Erviti, L.1
Seow, Y.2
Schapira, A.H.3
Gardiner, C.4
Sargent, I.L.5
Wood, M.J.A.6
Cooper, J.M.7
-
4
-
-
84862680670
-
Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo
-
Angot E, Steiner JA, Lema Tomé CM, Ekström P, Mattsson B, Björklund A, Brundin P (2012) Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo. PLoS ONE 7: e39465
-
(2012)
PLoS ONE
, vol.7
-
-
Angot, E.1
Steiner, J.A.2
Lema Tomé, C.M.3
Ekström, P.4
Mattsson, B.5
Björklund, A.6
Brundin, P.7
-
5
-
-
84904742860
-
Defined α-synuclein prion-like molecular assemblies spreading in cell culture
-
Aulić S, Le TTN, Moda F, Abounit S, Corvaglia S, Casalis L, Gustincich S, Zurzolo C, Tagliavini F, Legname G (2014) Defined α-synuclein prion-like molecular assemblies spreading in cell culture. BMC Neurosci 15: 69
-
(2014)
BMC Neurosci
, vol.15
, pp. 69
-
-
Aulić, S.1
Le, T.T.N.2
Moda, F.3
Abounit, S.4
Corvaglia, S.5
Casalis, L.6
Gustincich, S.7
Zurzolo, C.8
Tagliavini, F.9
Legname, G.10
-
7
-
-
84907360500
-
Glucocerebrosidase depletion enhances cell-to-cell transmission of α-synuclein
-
Bae E-J, Yang N-Y, Song M, Lee CS, Lee JS, Jung BC, Lee H-J, Kim S, Masliah E, Sardi SP, Lee S-J (2014) Glucocerebrosidase depletion enhances cell-to-cell transmission of α-synuclein. Nat Commun 5: 4755
-
(2014)
Nat Commun
, vol.5
, pp. 4755
-
-
Bae, E.-J.1
Yang, N.-Y.2
Song, M.3
Lee, C.S.4
Lee, J.S.5
Jung, B.C.6
Lee, H.-J.7
Kim, S.8
Masliah, E.9
Sardi, S.P.10
Lee, S.-J.11
-
8
-
-
84884250340
-
The function of α-synuclein
-
Bendor J, Logan T, Edwards R (2013) The function of α-synuclein. Neuron 79: 1044–1066
-
(2013)
Neuron
, vol.79
, pp. 1044-1066
-
-
Bendor, J.1
Logan, T.2
Edwards, R.3
-
9
-
-
84930757862
-
Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death
-
Bourdenx M, Bezard E, Dehay B (2014) Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death. Front Neuroanat 8: 83
-
(2014)
Front Neuroanat
, vol.8
, pp. 83
-
-
Bourdenx, M.1
Bezard, E.2
Dehay, B.3
-
10
-
-
84892150877
-
Structural and functional characterization of two alpha-synuclein strains
-
Bousset L, Pieri L, Ruiz-Arlandis G, Gath J, Jensen PH, Habenstein B, Madiona K, Olieric V, Böckmann A, Meier BH, Melki R (2013) Structural and functional characterization of two alpha-synuclein strains. Nat Commun 4: 2575
-
(2013)
Nat Commun
, vol.4
, pp. 2575
-
-
Bousset, L.1
Pieri, L.2
Ruiz-Arlandis, G.3
Gath, J.4
Jensen, P.H.5
Habenstein, B.6
Madiona, K.7
Olieric, V.8
Böckmann, A.9
Meier, B.H.10
Melki, R.11
-
11
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H, Del Tredici K, Rüb U, de Vos RA, Jansen Steur EN, Braak E (2003b) Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 24: 197–211
-
(2003)
Neurobiol Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rüb, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
12
-
-
0038748401
-
Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen
-
Braak H, Rüb U, Gai WP, Del Tredici K (2003a) Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen. J Neural Transm 110: 517–536
-
(2003)
J Neural Transm
, vol.110
, pp. 517-536
-
-
Braak, H.1
Rüb, U.2
Gai, W.P.3
Del Tredici, K.4
-
13
-
-
84961135800
-
Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1
-
Brahic M, Bousset L, Bieri G, Melki R, Gitler AD (2016) Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1. Acta Neuropathol 131: 539–548
-
(2016)
Acta Neuropathol
, vol.131
, pp. 539-548
-
-
Brahic, M.1
Bousset, L.2
Bieri, G.3
Melki, R.4
Gitler, A.D.5
-
14
-
-
84878994255
-
Properties of native brain α-synuclein
-
Burré J, Vivona S, Diao J, Sharma M, Brunger AT, Südhof TC (2013) Properties of native brain α-synuclein. Nature 498: E4–E6
-
(2013)
Nature
, vol.498
, pp. E4-E6
-
-
Burré, J.1
Vivona, S.2
Diao, J.3
Sharma, M.4
Brunger, A.T.5
Südhof, T.C.6
-
15
-
-
44449108230
-
Cutting edge: membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea
-
Chinnery HR, Pearlman E, McMenamin PG (2008) Cutting edge: membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea. J Immunol 180: 5779–5783
-
(2008)
J Immunol
, vol.180
, pp. 5779-5783
-
-
Chinnery, H.R.1
Pearlman, E.2
McMenamin, P.G.3
-
16
-
-
68149123529
-
Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions
-
Chu Y, Dodiya H, Aebischer P, Olanow CW, Kordower JH (2009) Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions. Neurobiol Dis 35: 385–398
-
(2009)
Neurobiol Dis
, vol.35
, pp. 385-398
-
-
Chu, Y.1
Dodiya, H.2
Aebischer, P.3
Olanow, C.W.4
Kordower, J.H.5
-
17
-
-
84883348572
-
Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes
-
Costanzo M, Abounit S, Marzo L, Danckaert A, Chamoun Z, Roux P, Zurzolo C (2013) Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes. J Cell Sci 126: 3678–3685
-
(2013)
J Cell Sci
, vol.126
, pp. 3678-3685
-
-
Costanzo, M.1
Abounit, S.2
Marzo, L.3
Danckaert, A.4
Chamoun, Z.5
Roux, P.6
Zurzolo, C.7
-
18
-
-
4344659685
-
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
-
Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D (2004) Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 305: 1292–1295
-
(2004)
Science
, vol.305
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stefanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
19
-
-
79251565507
-
Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity
-
Danzer KM, Ruf WP, Putcha P, Joyner D, Hashimoto T, Glabe C, Hyman BT, McLean PJ (2011) Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity. FASEB J 25: 326–336
-
(2011)
FASEB J
, vol.25
, pp. 326-336
-
-
Danzer, K.M.1
Ruf, W.P.2
Putcha, P.3
Joyner, D.4
Hashimoto, T.5
Glabe, C.6
Hyman, B.T.7
McLean, P.J.8
-
20
-
-
77956855813
-
Pathogenic lysosomal depletion in Parkinson's disease
-
Dehay B, Bové J, Rodríguez-Muela N, Perier C, Recasens A, Boya P, Vila M (2010) Pathogenic lysosomal depletion in Parkinson's disease. J Neurosci 30: 12535–12544
-
(2010)
J Neurosci
, vol.30
, pp. 12535-12544
-
-
Dehay, B.1
Bové, J.2
Rodríguez-Muela, N.3
Perier, C.4
Recasens, A.5
Boya, P.6
Vila, M.7
-
21
-
-
69149089854
-
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein
-
Desplats P, Lee H-J, Bae E-J, Patrick C, Rockenstein E, Crews L, Spencer B, Masliah E, Lee S-J (2009) Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc Natl Acad Sci USA 106: 13010–13015
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13010-13015
-
-
Desplats, P.1
Lee, H.-J.2
Bae, E.-J.3
Patrick, C.4
Rockenstein, E.5
Crews, L.6
Spencer, B.7
Masliah, E.8
Lee, S.-J.9
-
22
-
-
84943414298
-
Exposure to ALS-FTD-CSF generates TDP-43 aggregates in glioblastoma cells through exosomes and TNTs-like structure
-
Ding X, Ma M, Teng J, Teng RKF, Zhou S, Yin J, Fonkem E, Huang JH, Wu E, Wang X (2015) Exposure to ALS-FTD-CSF generates TDP-43 aggregates in glioblastoma cells through exosomes and TNTs-like structure. Oncotarget 6: 24178–24191
-
(2015)
Oncotarget
, vol.6
, pp. 24178-24191
-
-
Ding, X.1
Ma, M.2
Teng, J.3
Teng, R.K.F.4
Zhou, S.5
Yin, J.6
Fonkem, E.7
Huang, J.H.8
Wu, E.9
Wang, X.10
-
23
-
-
84876722731
-
Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis
-
Freeman D, Cedillos R, Choyke S, Lukic Z, McGuire K, Marvin S, Burrage AM, Sudholt S, Rana A, O'Connor C, Wiethoff CM, Campbell EM (2013) Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis. PLoS ONE 8: e62143
-
(2013)
PLoS ONE
, vol.8
-
-
Freeman, D.1
Cedillos, R.2
Choyke, S.3
Lukic, Z.4
McGuire, K.5
Marvin, S.6
Burrage, A.M.7
Sudholt, S.8
Rana, A.9
O'Connor, C.10
Wiethoff, C.M.11
Campbell, E.M.12
-
24
-
-
84868148328
-
Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport
-
Freundt EC, Maynard N, Clancy EK, Roy S, Bousset L, Sourigues Y, Covert M, Melki R, Kirkegaard K, Brahic M (2012) Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport. Ann Neurol 72: 517–524
-
(2012)
Ann Neurol
, vol.72
, pp. 517-524
-
-
Freundt, E.C.1
Maynard, N.2
Clancy, E.K.3
Roy, S.4
Bousset, L.5
Sourigues, Y.6
Covert, M.7
Melki, R.8
Kirkegaard, K.9
Brahic, M.10
-
25
-
-
23844531539
-
PA700, the regulatory complex of the 26S proteasome, interferes with alpha-synuclein assembly
-
Ghee M, Melki R, Michot N, Mallet J (2005) PA700, the regulatory complex of the 26S proteasome, interferes with alpha-synuclein assembly. FEBS J 272: 4023–4033
-
(2005)
FEBS J
, vol.272
, pp. 4023-4033
-
-
Ghee, M.1
Melki, R.2
Michot, N.3
Mallet, J.4
-
26
-
-
67649371158
-
Tunnelling nanotubes: a highway for prion spreading?
-
Gousset K, Zurzolo C (2009) Tunnelling nanotubes: a highway for prion spreading? Prion 3: 94–98
-
(2009)
Prion
, vol.3
, pp. 94-98
-
-
Gousset, K.1
Zurzolo, C.2
-
27
-
-
61849178720
-
Prions hijack tunnelling nanotubes for intercellular spread
-
Gousset K, Schiff E, Langevin C, Marijanovic Z, Caputo A, Browman DT, Chenouard N, de Chaumont F, Martino A, Enninga J, Olivo-Marin J-C, Männel D, Zurzolo C (2009) Prions hijack tunnelling nanotubes for intercellular spread. Nat Cell Biol 11: 328–336
-
(2009)
Nat Cell Biol
, vol.11
, pp. 328-336
-
-
Gousset, K.1
Schiff, E.2
Langevin, C.3
Marijanovic, Z.4
Caputo, A.5
Browman, D.T.6
Chenouard, N.7
de Chaumont, F.8
Martino, A.9
Enninga, J.10
Olivo-Marin, J.-C.11
Männel, D.12
Zurzolo, C.13
-
28
-
-
84885448134
-
Myo10 is a key regulator of TNT formation in neuronal cells
-
Gousset K, Marzo L, Commere P-H, Zurzolo C (2013) Myo10 is a key regulator of TNT formation in neuronal cells. J Cell Sci 126: 4424–4435
-
(2013)
J Cell Sci
, vol.126
, pp. 4424-4435
-
-
Gousset, K.1
Marzo, L.2
Commere, P.-H.3
Zurzolo, C.4
-
29
-
-
79551519276
-
α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
-
Hansen C, Angot E, Bergström A-L, Steiner JA, Pieri L, Paul G, Outeiro TF, Melki R, Kallunki P, Fog K, Li J-Y, Brundin P (2011) α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. J Clin Invest 121: 715–725
-
(2011)
J Clin Invest
, vol.121
, pp. 715-725
-
-
Hansen, C.1
Angot, E.2
Bergström, A.-L.3
Steiner, J.A.4
Pieri, L.5
Paul, G.6
Outeiro, T.F.7
Melki, R.8
Kallunki, P.9
Fog, K.10
Li, J.-Y.11
Brundin, P.12
-
30
-
-
84055207529
-
The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein
-
Hasegawa T, Konno M, Baba T, Sugeno N, Kikuchi A, Kobayashi M, Miura E, Tanaka N, Tamai K, Furukawa K, Arai H, Mori F, Wakabayashi K, Aoki M, Itoyama Y, Takeda A (2011) The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein. PLoS ONE 6: e29460
-
(2011)
PLoS ONE
, vol.6
-
-
Hasegawa, T.1
Konno, M.2
Baba, T.3
Sugeno, N.4
Kikuchi, A.5
Kobayashi, M.6
Miura, E.7
Tanaka, N.8
Tamai, K.9
Furukawa, K.10
Arai, H.11
Mori, F.12
Wakabayashi, K.13
Aoki, M.14
Itoyama, Y.15
Takeda, A.16
-
31
-
-
84922092995
-
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
-
Holmqvist S, Chutna O, Bousset L, Aldrin-Kirk P, Li W, Björklund T, Wang ZY, Roybon L, Melki R, Li JY (2014) Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats. Acta Neuropathol 128: 805–820
-
(2014)
Acta Neuropathol
, vol.128
, pp. 805-820
-
-
Holmqvist, S.1
Chutna, O.2
Bousset, L.3
Aldrin-Kirk, P.4
Li, W.5
Björklund, T.6
Wang, Z.Y.7
Roybon, L.8
Melki, R.9
Li, J.Y.10
-
32
-
-
79960334171
-
α-Synuclein aggregation and transmission are enhanced by leucine-rich repeat kinase 2 in human neuroblastoma SH-SY5Y cells
-
Kondo K, Obitsu S, Teshima R (2011) α-Synuclein aggregation and transmission are enhanced by leucine-rich repeat kinase 2 in human neuroblastoma SH-SY5Y cells. Biol Pharm Bull 34: 1078–1083
-
(2011)
Biol Pharm Bull
, vol.34
, pp. 1078-1083
-
-
Kondo, K.1
Obitsu, S.2
Teshima, R.3
-
33
-
-
84864915936
-
Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy
-
Konno M, Hasegawa T, Baba T, Miura E, Sugeno N, Kikuchi A, Fiesel FC, Sasaki T, Aoki M, Itoyama Y, Takeda A (2012) Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy. Mol Neurodegener 7: 38
-
(2012)
Mol Neurodegener
, vol.7
, pp. 38
-
-
Konno, M.1
Hasegawa, T.2
Baba, T.3
Miura, E.4
Sugeno, N.5
Kikuchi, A.6
Fiesel, F.C.7
Sasaki, T.8
Aoki, M.9
Itoyama, Y.10
Takeda, A.11
-
34
-
-
43249114934
-
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
-
Kordower JH, Chu Y, Hauser RA, Freeman TB, Olanow CW (2008) Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat Med 14: 504–506
-
(2008)
Nat Med
, vol.14
, pp. 504-506
-
-
Kordower, J.H.1
Chu, Y.2
Hauser, R.A.3
Freeman, T.B.4
Olanow, C.W.5
-
35
-
-
79960285197
-
Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat
-
Kordower JH, Dodiya HB, Kordower AM, Terpstra B, Paumier K, Madhavan L, Sortwell C, Steece-Collier K, Collier TJ (2011) Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat. Neurobiol Dis 43: 552–557
-
(2011)
Neurobiol Dis
, vol.43
, pp. 552-557
-
-
Kordower, J.H.1
Dodiya, H.B.2
Kordower, A.M.3
Terpstra, B.4
Paumier, K.5
Madhavan, L.6
Sortwell, C.7
Steece-Collier, K.8
Collier, T.J.9
-
36
-
-
44749083979
-
Assembly-dependent endocytosis and clearance of extracellular α-synuclein
-
Lee HJ, Suk JE, Bae EJ, Lee JH, Paik SR, Lee SJ (2008) Assembly-dependent endocytosis and clearance of extracellular α-synuclein. Int J Biochem Cell Biol 40: 1835–1849
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 1835-1849
-
-
Lee, H.J.1
Suk, J.E.2
Bae, E.J.3
Lee, J.H.4
Paik, S.R.5
Lee, S.J.6
-
37
-
-
77950571596
-
Direct transfer of Alpha -synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies
-
Lee HJ, Suk JE, Patrick C, Bae EJ, Cho JH, Rho S, Hwang D, Masliah E, Lee SJ (2010) Direct transfer of Alpha -synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies. J Biol Chem 285: 9262–9272
-
(2010)
J Biol Chem
, vol.285
, pp. 9262-9272
-
-
Lee, H.J.1
Suk, J.E.2
Patrick, C.3
Bae, E.J.4
Cho, J.H.5
Rho, S.6
Hwang, D.7
Masliah, E.8
Lee, S.J.9
-
38
-
-
84881147729
-
Autophagic failure promotes the exocytosis and intercellular transfer of α-synuclein
-
Lee H-J, Cho E-D, Lee KW, Kim J-H, Cho S-G, Lee S-J (2013) Autophagic failure promotes the exocytosis and intercellular transfer of α-synuclein. Exp Mol Med 45: e22
-
(2013)
Exp Mol Med
, vol.45
-
-
Lee, H.-J.1
Cho, E.-D.2
Lee, K.W.3
Kim, J.-H.4
Cho, S.-G.5
Lee, S.-J.6
-
39
-
-
43249110200
-
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
-
Li J-Y, Englund E, Holton JL, Soulet D, Hagell P, Lees AJ, Lashley T, Quinn NP, Rehncrona S, Björklund A, Widner H, Revesz T, Lindvall O, Brundin P (2008) Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation. Nat Med 14: 501–503
-
(2008)
Nat Med
, vol.14
, pp. 501-503
-
-
Li, J.-Y.1
Englund, E.2
Holton, J.L.3
Soulet, D.4
Hagell, P.5
Lees, A.J.6
Lashley, T.7
Quinn, N.P.8
Rehncrona, S.9
Björklund, A.10
Widner, H.11
Revesz, T.12
Lindvall, O.13
Brundin, P.14
-
40
-
-
59649097036
-
Rab11a and HSP90 regulate recycling of extracellular alpha-synuclein
-
Liu J, Zhang J-P, Shi M, Quinn T, Bradner J, Beyer R, Chen S, Zhang J (2009) Rab11a and HSP90 regulate recycling of extracellular alpha-synuclein. J Neurosci 29: 1480–1485
-
(2009)
J Neurosci
, vol.29
, pp. 1480-1485
-
-
Liu, J.1
Zhang, J.-P.2
Shi, M.3
Quinn, T.4
Bradner, J.5
Beyer, R.6
Chen, S.7
Zhang, J.8
-
41
-
-
84857926403
-
Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma
-
Lou E, Fujisawa S, Morozov A, Barlas A, Romin Y, Dogan Y, Gholami S, Moreira AL, Manova-Todorova K, Moore MAS (2012) Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma. PLoS ONE 7: e33093
-
(2012)
PLoS ONE
, vol.7
-
-
Lou, E.1
Fujisawa, S.2
Morozov, A.3
Barlas, A.4
Romin, Y.5
Dogan, Y.6
Gholami, S.7
Moreira, A.L.8
Manova-Todorova, K.9
Moore, M.A.S.10
-
42
-
-
84869109864
-
Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice
-
Luk KC, Kehm V, Carroll J, Zhang B, O'Brien P, Trojanowski JQ, Lee VM-Y (2012b) Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice. Science 338: 949–953
-
(2012)
Science
, vol.338
, pp. 949-953
-
-
Luk, K.C.1
Kehm, V.2
Carroll, J.3
Zhang, B.4
O'Brien, P.5
Trojanowski, J.Q.6
Lee, V.M.-Y.7
-
43
-
-
84862609075
-
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
-
Luk KC, Kehm VM, Zhang B, O'Brien P, Trojanowski JQ, Lee VMY (2012a) Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice. J Exp Med 209: 975–986
-
(2012)
J Exp Med
, vol.209
, pp. 975-986
-
-
Luk, K.C.1
Kehm, V.M.2
Zhang, B.3
O'Brien, P.4
Trojanowski, J.Q.5
Lee, V.M.Y.6
-
44
-
-
77951541740
-
Lysosomal degradation of alpha-synuclein in vivo
-
Mak SK, McCormack AL, Manning-Bog AB, Cuervo AM, Di Monte DA (2010) Lysosomal degradation of alpha-synuclein in vivo. J Biol Chem 285: 13621–13629
-
(2010)
J Biol Chem
, vol.285
, pp. 13621-13629
-
-
Mak, S.K.1
McCormack, A.L.2
Manning-Bog, A.B.3
Cuervo, A.M.4
Di Monte, D.A.5
-
45
-
-
84866327994
-
Multifaceted roles of tunneling nanotubes in intercellular communication
-
Marzo L, Gousset K, Zurzolo C (2012) Multifaceted roles of tunneling nanotubes in intercellular communication. Front Physiol 3: 1–14
-
(2012)
Front Physiol
, vol.3
, pp. 1-14
-
-
Marzo, L.1
Gousset, K.2
Zurzolo, C.3
-
46
-
-
84876057762
-
Prion-like spreading of pathological α-synuclein in brain
-
Masuda-Suzukake M, Nonaka T, Hosokawa M, Oikawa T, Arai T, Akiyama H, Mann DMA, Hasegawa M (2013) Prion-like spreading of pathological α-synuclein in brain. Brain 136: 1128–1138
-
(2013)
Brain
, vol.136
, pp. 1128-1138
-
-
Masuda-Suzukake, M.1
Nonaka, T.2
Hosokawa, M.3
Oikawa, T.4
Arai, T.5
Akiyama, H.6
Mann, D.M.A.7
Hasegawa, M.8
-
47
-
-
85048243758
-
Pathological alpha-synuclein propagates through neural networks
-
Masuda-Suzukake M, Nonaka T, Hosokawa M, Kubo M, Shimozawa A, Akiyama H, Hasegawa M (2014) Pathological alpha-synuclein propagates through neural networks. Acta Neuropathol Commun 2: 88
-
(2014)
Acta Neuropathol Commun
, vol.2
, pp. 88
-
-
Masuda-Suzukake, M.1
Nonaka, T.2
Hosokawa, M.3
Kubo, M.4
Shimozawa, A.5
Akiyama, H.6
Hasegawa, M.7
-
49
-
-
84863433677
-
Prion-like acceleration of a synucleinopathy in a transgenic mouse model
-
Mougenot AL, Nicot S, Bencsik A, Morignat E, Verchère J, Lakhdar L, Legastelois S, Baron T (2012) Prion-like acceleration of a synucleinopathy in a transgenic mouse model. Neurobiol Aging 33: 2225–2228
-
(2012)
Neurobiol Aging
, vol.33
, pp. 2225-2228
-
-
Mougenot, A.L.1
Nicot, S.2
Bencsik, A.3
Morignat, E.4
Verchère, J.5
Lakhdar, L.6
Legastelois, S.7
Baron, T.8
-
50
-
-
84919430362
-
Brief reports: lysosomal cross-correction by hematopoietic stem cell-derived macrophages via tunneling nanotubes
-
Naphade S, Sharma J, Gaide Chevronnay HP, Shook MA, Yeagy BA, Rocca CJ, Ur SN, Lau AJ, Courtoy PJ, Cherqui S (2015) Brief reports: lysosomal cross-correction by hematopoietic stem cell-derived macrophages via tunneling nanotubes. Stem Cells 33: 301–309
-
(2015)
Stem Cells
, vol.33
, pp. 301-309
-
-
Naphade, S.1
Sharma, J.2
Gaide Chevronnay, H.P.3
Shook, M.A.4
Yeagy, B.A.5
Rocca, C.J.6
Ur, S.N.7
Lau, A.J.8
Courtoy, P.J.9
Cherqui, S.10
-
51
-
-
84882254367
-
The role of autophagy in neurodegenerative disease
-
Nixon RA (2013) The role of autophagy in neurodegenerative disease. Nat Med 19: 983–997
-
(2013)
Nat Med
, vol.19
, pp. 983-997
-
-
Nixon, R.A.1
-
52
-
-
3242767507
-
Cutting edge: membrane nanotubes connect immune cells
-
Onfelt B, Nedvetzki S, Yanagi K, Davis DM (2004) Cutting edge: membrane nanotubes connect immune cells. J Immunol 173: 1511–1513
-
(2004)
J Immunol
, vol.173
, pp. 1511-1513
-
-
Onfelt, B.1
Nedvetzki, S.2
Yanagi, K.3
Davis, D.M.4
-
53
-
-
84949293502
-
Brain tumour cells interconnect to a functional and resistant network
-
Osswald M, Jung E, Sahm F, Solecki G, Venkataramani V, Blaes J, Weil S, Horstman H, Wiestler B, Syed M, Huang L, Ratliff M, Karimian Jazi K, Kurz FT, Schmenger T, Lemke D, Gömmel M, Pauli M, Liao Y, Häring P et al (2015) Brain tumour cells interconnect to a functional and resistant network. Nature 528: 93–98
-
(2015)
Nature
, vol.528
, pp. 93-98
-
-
Osswald, M.1
Jung, E.2
Sahm, F.3
Solecki, G.4
Venkataramani, V.5
Blaes, J.6
Weil, S.7
Horstman, H.8
Wiestler, B.9
Syed, M.10
Huang, L.11
Ratliff, M.12
Karimian Jazi, K.13
Kurz, F.T.14
Schmenger, T.15
Lemke, D.16
Gömmel, M.17
Pauli, M.18
Liao, Y.19
Häring, P.20
more..
-
54
-
-
84857746017
-
Different modalities of intercellular membrane exchanges mediate cell-to-cell P-glycoprotein transfers in MCF-7 breast cancer cells
-
Pasquier J, Galas L, Boulangé-Lecomte C, Rioult D, Bultelle F, Magal P, Webb G, Le Foll F (2012) Different modalities of intercellular membrane exchanges mediate cell-to-cell P-glycoprotein transfers in MCF-7 breast cancer cells. J Biol Chem 287: 7374–7387
-
(2012)
J Biol Chem
, vol.287
, pp. 7374-7387
-
-
Pasquier, J.1
Galas, L.2
Boulangé-Lecomte, C.3
Rioult, D.4
Bultelle, F.5
Magal, P.6
Webb, G.7
Le Foll, F.8
-
55
-
-
84934983329
-
α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
-
Peelaerts W, Bousset L, Van der Perren A, Moskalyuk A, Pulizzi R, Giugliano M, Van den Haute C, Melki R, Baekelandt V (2015) α-Synuclein strains cause distinct synucleinopathies after local and systemic administration. Nature 522: 340–344
-
(2015)
Nature
, vol.522
, pp. 340-344
-
-
Peelaerts, W.1
Bousset, L.2
Van der Perren, A.3
Moskalyuk, A.4
Pulizzi, R.5
Giugliano, M.6
Van den Haute, C.7
Melki, R.8
Baekelandt, V.9
-
56
-
-
84862701723
-
Fibrillar α -synuclein and huntingtin exon 1 assemblies are toxic to the cells
-
Pieri L, Madiona K, Bousset L, Melki R (2012) Fibrillar α -synuclein and huntingtin exon 1 assemblies are toxic to the cells. Biophys J 102: 2894–2905
-
(2012)
Biophys J
, vol.102
, pp. 2894-2905
-
-
Pieri, L.1
Madiona, K.2
Bousset, L.3
Melki, R.4
-
57
-
-
84897977607
-
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
-
Recasens A, Dehay B, Bové J, Carballo-Carbajal I, Dovero S, Pérez-Villalba A, Fernagut PO, Blesa J, Parent A, Perier C, Fariñas I, Obeso JA, Bezard E, Vila M (2014) Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Ann Neurol 75: 351–362
-
(2014)
Ann Neurol
, vol.75
, pp. 351-362
-
-
Recasens, A.1
Dehay, B.2
Bové, J.3
Carballo-Carbajal, I.4
Dovero, S.5
Pérez-Villalba, A.6
Fernagut, P.O.7
Blesa, J.8
Parent, A.9
Perier, C.10
Fariñas, I.11
Obeso, J.A.12
Bezard, E.13
Vila, M.14
-
58
-
-
84885470591
-
Transfer of human alpha-synuclein from the olfactory bulb to interconnected brain regions in mice
-
Rey NL, Petit GH, Bousset L, Melki R, Brundin P (2013) Transfer of human alpha-synuclein from the olfactory bulb to interconnected brain regions in mice. Acta Neuropathol 126: 555–573
-
(2013)
Acta Neuropathol
, vol.126
, pp. 555-573
-
-
Rey, N.L.1
Petit, G.H.2
Bousset, L.3
Melki, R.4
Brundin, P.5
-
59
-
-
84892538035
-
Alpha-synuclein transfers from neurons to oligodendrocytes
-
Reyes JF, Rey NL, Bousset L, Melki R, Brundin P, Angot E (2014) Alpha-synuclein transfers from neurons to oligodendrocytes. Glia 62: 387–398
-
(2014)
Glia
, vol.62
, pp. 387-398
-
-
Reyes, J.F.1
Rey, N.L.2
Bousset, L.3
Melki, R.4
Brundin, P.5
Angot, E.6
-
60
-
-
1142286348
-
Nanotubular highways for intercellular organelle transport
-
Rustom A, Saffrich R, Markovic I, Walther P, Gerdes H-H (2004) Nanotubular highways for intercellular organelle transport. Science 303: 1007–1010
-
(2004)
Science
, vol.303
, pp. 1007-1010
-
-
Rustom, A.1
Saffrich, R.2
Markovic, I.3
Walther, P.4
Gerdes, H.-H.5
-
61
-
-
84872137228
-
Membrane nanotubes in myeloid cells in the adult mouse cornea represent a novel mode of immune cell interaction
-
Seyed-Razavi Y, Hickey MJ, Kuffova L, McMenamin PG, Chinnery HR (2013) Membrane nanotubes in myeloid cells in the adult mouse cornea represent a novel mode of immune cell interaction. Immunol Cell Biol 91: 89–95
-
(2013)
Immunol Cell Biol
, vol.91
, pp. 89-95
-
-
Seyed-Razavi, Y.1
Hickey, M.J.2
Kuffova, L.3
McMenamin, P.G.4
Chinnery, H.R.5
-
62
-
-
38849168755
-
Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission
-
Sowinski S, Jolly C, Berninghausen O, Purbhoo MA, Chauveau A, Köhler K, Oddos S, Eissmann P, Brodsky FM, Hopkins C, Onfelt B, Sattentau Q, Davis DM (2008) Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission. Nat Cell Biol 10: 211–219
-
(2008)
Nat Cell Biol
, vol.10
, pp. 211-219
-
-
Sowinski, S.1
Jolly, C.2
Berninghausen, O.3
Purbhoo, M.A.4
Chauveau, A.5
Köhler, K.6
Oddos, S.7
Eissmann, P.8
Brodsky, F.M.9
Hopkins, C.10
Onfelt, B.11
Sattentau, Q.12
Davis, D.M.13
-
63
-
-
70350550208
-
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases
-
Spencer B, Potkar R, Trejo M, Rockenstein E, Patrick C, Gindi R, Adame A, Wyss-Coray T, Masliah E (2009) Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases. J Neurosci 29: 13578–13588
-
(2009)
J Neurosci
, vol.29
, pp. 13578-13588
-
-
Spencer, B.1
Potkar, R.2
Trejo, M.3
Rockenstein, E.4
Patrick, C.5
Gindi, R.6
Adame, A.7
Wyss-Coray, T.8
Masliah, E.9
-
64
-
-
0035920226
-
Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein
-
Sung JY, Kim J, Paik SR, Park JH, Ahn YS, Chung KC (2001) Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein. J Biol Chem 276: 27441–27448
-
(2001)
J Biol Chem
, vol.276
, pp. 27441-27448
-
-
Sung, J.Y.1
Kim, J.2
Paik, S.R.3
Park, J.H.4
Ahn, Y.S.5
Chung, K.C.6
-
65
-
-
84878230429
-
Lewy body-like alpha-synuclein aggregates resist degradation and impair macroautophagy
-
Tanik SA, Schultheiss CE, Volpicelli-Daley LA, Brunden KR, Lee VMY (2013) Lewy body-like alpha-synuclein aggregates resist degradation and impair macroautophagy. J Biol Chem 288: 15194–15210
-
(2013)
J Biol Chem
, vol.288
, pp. 15194-15210
-
-
Tanik, S.A.1
Schultheiss, C.E.2
Volpicelli-Daley, L.A.3
Brunden, K.R.4
Lee, V.M.Y.5
-
66
-
-
33748325848
-
Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease
-
Tokuda T, Salem SA, Allsop D, Mizuno T, Nakagawa M, Qureshi MM, Locascio JJ, Schlossmacher MG, El-Agnaf OMA (2006) Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease. Biochem Biophys Res Commun 349: 162–166
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 162-166
-
-
Tokuda, T.1
Salem, S.A.2
Allsop, D.3
Mizuno, T.4
Nakagawa, M.5
Qureshi, M.M.6
Locascio, J.J.7
Schlossmacher, M.G.8
El-Agnaf, O.M.A.9
-
67
-
-
84907033533
-
Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates
-
Volpicelli-Daley LA, Luk KC, Lee VM (2014) Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates. Nat Protoc 9: 2135–2146
-
(2014)
Nat Protoc
, vol.9
, pp. 2135-2146
-
-
Volpicelli-Daley, L.A.1
Luk, K.C.2
Lee, V.M.3
-
68
-
-
79952619322
-
Tunneling-nanotube development in astrocytes depends on p53 activation
-
Wang Y, Cui J, Sun X, Zhang Y (2011) Tunneling-nanotube development in astrocytes depends on p53 activation. Cell Death Differ 18: 732–742
-
(2011)
Cell Death Differ
, vol.18
, pp. 732-742
-
-
Wang, Y.1
Cui, J.2
Sun, X.3
Zhang, Y.4
-
69
-
-
81055149523
-
Tunneling nanotubes mediate rescue of prematurely senescent endothelial cells by endothelial progenitors: exchange of lysosomal pool
-
Yasuda K, Khandare A, Burianovskyy L, Maruyama S, Zhang F, Nasjletti A, Goligorsky MS (2011) Tunneling nanotubes mediate rescue of prematurely senescent endothelial cells by endothelial progenitors: exchange of lysosomal pool. Aging 3: 597–608
-
(2011)
Aging
, vol.3
, pp. 597-608
-
-
Yasuda, K.1
Khandare, A.2
Burianovskyy, L.3
Maruyama, S.4
Zhang, F.5
Nasjletti, A.6
Goligorsky, M.S.7
-
70
-
-
68549111280
-
The lysosome and neurodegenerative diseases structure and function of lysosomes
-
Zhang L, Sheng R, Qin Z (2009) The lysosome and neurodegenerative diseases structure and function of lysosomes. Acta Biochim Biophys Sin 41: 437–445
-
(2009)
Acta Biochim Biophys Sin
, vol.41
, pp. 437-445
-
-
Zhang, L.1
Sheng, R.2
Qin, Z.3
-
71
-
-
84939440707
-
Prion aggregates transfer through tunneling nanotubes in endocytic vesicles
-
Zhu S, Victoria GS, Marzo L, Ghosh R, Zurzolo C (2015) Prion aggregates transfer through tunneling nanotubes in endocytic vesicles. Prion 9: 125–135
-
(2015)
Prion
, vol.9
, pp. 125-135
-
-
Zhu, S.1
Victoria, G.S.2
Marzo, L.3
Ghosh, R.4
Zurzolo, C.5
|