Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions

Neurobiology of Disease

Volumn 35, Issue 3, 2009, Pages 385-398

  Chu, Yaping ^a   Dodiya, Hemraj ^a   Aebischer, Patrick ^b   Olanow, C Warren ^c   Kordower, Jeffrey H ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b EPFL   (Switzerland)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Alpha synuclein; Lysosome; Parkinson's disease; Proteasome

Indexed keywords

ALPHA SYNUCLEIN; CATHEPSIN D; HEAT SHOCK PROTEIN 73; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; NEUROMELANIN; PROTEASOME; UBIQUITIN; VIRUS VECTOR;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL INCLUSION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOTHESIS; IMMUNOREACTIVITY; LYSOSOME; MALE; MUTANT; NERVE CELL; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; RAT; SUBSTANTIA NIGRA;

AGED; AGED, 80 AND OVER; ALPHA-SYNUCLEIN; ANIMALS; CATHEPSIN D; FEMALE; GENETIC VECTORS; HSC70 HEAT-SHOCK PROTEINS; HUMANS; INCLUSION BODIES; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MALE; MELANINS; MUTATION; NEURONS; PARKINSON DISEASE; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA;

EID: 68149123529     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2009.05.023     Document Type: Article

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