-
1
-
-
3142743111
-
Neonatal adaptive immunity comes of age
-
COI: 1:CAS:528:DC%2BD2cXlt1Cqurg%3D, PID: 15229474
-
Adkins B, Leclerc C, Marshall-Clarke S (2004) Neonatal adaptive immunity comes of age. Nat Rev Immunol 4:553–564
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 553-564
-
-
Adkins, B.1
Leclerc, C.2
Marshall-Clarke, S.3
-
2
-
-
78649733432
-
Allergic airway inflammation induces a pro-secretory epithelial ion transport phenotype in mice
-
COI: 1:STN:280:DC%2BC3M%2FgsFCjtg%3D%3D, PID: 20413543
-
Anagnostopoulou P, Dai L, Schatterny J, Hirtz S, Duerr J, Mall MA (2010) Allergic airway inflammation induces a pro-secretory epithelial ion transport phenotype in mice. Eur Respir J 36:1436–1447
-
(2010)
Eur Respir J
, vol.36
, pp. 1436-1447
-
-
Anagnostopoulou, P.1
Dai, L.2
Schatterny, J.3
Hirtz, S.4
Duerr, J.5
Mall, M.A.6
-
3
-
-
84867181870
-
SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation
-
COI: 1:CAS:528:DC%2BC38XhsV2it77I, PID: 22945630
-
Anagnostopoulou P, Riederer B, Duerr J, Michel S, Binia A, Agrawal R, Liu X, Kalitzki K, Xiao F, Chen M, Schatterny J, Hartmann D, Thum T, Kabesch M, Soleimani M, Seidler U, Mall MA (2012) SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation. J Clin Invest 122:3629–3634
-
(2012)
J Clin Invest
, vol.122
, pp. 3629-3634
-
-
Anagnostopoulou, P.1
Riederer, B.2
Duerr, J.3
Michel, S.4
Binia, A.5
Agrawal, R.6
Liu, X.7
Kalitzki, K.8
Xiao, F.9
Chen, M.10
Schatterny, J.11
Hartmann, D.12
Thum, T.13
Kabesch, M.14
Soleimani, M.15
Seidler, U.16
Mall, M.A.17
-
4
-
-
84938081322
-
The relationship of mucus concentration (Hydration) to mucus osmotic pressure and transport in chronic bronchitis
-
PID: 25909230
-
Anderson WH, Coakley RD, Button B, Henderson AG, Zeman KL, Alexis NE, Peden DB, Lazarowski ER, Davis CW, Bailey S, Fuller F, Almond M, Qaqish B, Bordonali E, Rubinstein M, Bennett WD, Kesimer M, Boucher RC (2015) The relationship of mucus concentration (Hydration) to mucus osmotic pressure and transport in chronic bronchitis. Am J Respir Crit Care Med 192:182–190
-
(2015)
Am J Respir Crit Care Med
, vol.192
, pp. 182-190
-
-
Anderson, W.H.1
Coakley, R.D.2
Button, B.3
Henderson, A.G.4
Zeman, K.L.5
Alexis, N.E.6
Peden, D.B.7
Lazarowski, E.R.8
Davis, C.W.9
Bailey, S.10
Fuller, F.11
Almond, M.12
Qaqish, B.13
Bordonali, E.14
Rubinstein, M.15
Bennett, W.D.16
Kesimer, M.17
Boucher, R.C.18
-
5
-
-
84884530496
-
Characterization of SLC26A9 in patients with CF-like lung disease
-
COI: 1:CAS:528:DC%2BC3sXhsFensrzE, PID: 24272871
-
Bakouh N, Bienvenu T, Thomas A, Ehrenfeld J, Liote H, Roussel D, Duquesnoy P, Farman N, Viel M, Cherif-Zahar B, Amselem S, Taam RA, Edelman A, Planelles G, Sermet-Gaudelus I (2013) Characterization of SLC26A9 in patients with CF-like lung disease. Hum Mutat 34:1404–1414
-
(2013)
Hum Mutat
, vol.34
, pp. 1404-1414
-
-
Bakouh, N.1
Bienvenu, T.2
Thomas, A.3
Ehrenfeld, J.4
Liote, H.5
Roussel, D.6
Duquesnoy, P.7
Farman, N.8
Viel, M.9
Cherif-Zahar, B.10
Amselem, S.11
Taam, R.A.12
Edelman, A.13
Planelles, G.14
Sermet-Gaudelus, I.15
-
6
-
-
0020505359
-
Impaired tracheobronchial clearance in patients with mild stable asthma
-
COI: 1:STN:280:DyaL3s3ns1elsQ%3D%3D, PID: 6879499
-
Bateman JR, Pavia D, Sheahan NF, Agnew JE, Clarke SW (1983) Impaired tracheobronchial clearance in patients with mild stable asthma. Thorax 38:463–467
-
(1983)
Thorax
, vol.38
, pp. 463-467
-
-
Bateman, J.R.1
Pavia, D.2
Sheahan, N.F.3
Agnew, J.E.4
Clarke, S.W.5
-
7
-
-
0025096271
-
Mucociliary clearance from central airways in patients with excessive sputum production with and without primary ciliary dyskinesia
-
COI: 1:STN:280:DyaK3czmslGntw%3D%3D, PID: 2394139
-
Baum GL, Zwas ST, Katz I, Roth Y (1990) Mucociliary clearance from central airways in patients with excessive sputum production with and without primary ciliary dyskinesia. Chest 98:608–612
-
(1990)
Chest
, vol.98
, pp. 608-612
-
-
Baum, G.L.1
Zwas, S.T.2
Katz, I.3
Roth, Y.4
-
8
-
-
79958104493
-
Pharmacological therapy for cystic fibrosis: from bench to bedside
-
COI: 1:CAS:528:DC%2BC3MXpsVGju7g%3D, PID: 21658632
-
Becq F, Mall MA, Sheppard DN, Conese M, Zegarra-Moran O (2011) Pharmacological therapy for cystic fibrosis: from bench to bedside. J Cyst Fibros 10(Suppl 2):S129–S145
-
(2011)
J Cyst Fibros
, vol.10
, pp. S129-S145
-
-
Becq, F.1
Mall, M.A.2
Sheppard, D.N.3
Conese, M.4
Zegarra-Moran, O.5
-
9
-
-
64549085967
-
SLC26A9 is a constitutively active, CFTR-regulated anion conductance in human bronchial epithelia
-
COI: 1:CAS:528:DC%2BD1MXltVOlt78%3D, PID: 19289574
-
Bertrand CA, Zhang R, Pilewski JM, Frizzell RA (2009) SLC26A9 is a constitutively active, CFTR-regulated anion conductance in human bronchial epithelia. J Gen Physiol 133:421–438
-
(2009)
J Gen Physiol
, vol.133
, pp. 421-438
-
-
Bertrand, C.A.1
Zhang, R.2
Pilewski, J.M.3
Frizzell, R.A.4
-
10
-
-
84907833958
-
A functional anatomic defect of the cystic fibrosis airway
-
PID: 25029666
-
Birket SE, Chu KK, Liu L, Houser GH, Diephuis BJ, Wilsterman EJ, Dierksen G, Mazur M, Shastry S, Li Y, Watson JD, Smith AT, Schuster BS, Hanes J, Grizzle WE, Sorscher EJ, Tearney GJ, Rowe SM (2014) A functional anatomic defect of the cystic fibrosis airway. Am J Respir Crit Care Med 190:421–432
-
(2014)
Am J Respir Crit Care Med
, vol.190
, pp. 421-432
-
-
Birket, S.E.1
Chu, K.K.2
Liu, L.3
Houser, G.H.4
Diephuis, B.J.5
Wilsterman, E.J.6
Dierksen, G.7
Mazur, M.8
Shastry, S.9
Li, Y.10
Watson, J.D.11
Smith, A.T.12
Schuster, B.S.13
Hanes, J.14
Grizzle, W.E.15
Sorscher, E.J.16
Tearney, G.J.17
Rowe, S.M.18
-
11
-
-
80052376691
-
Morphological analysis of the trachea and pattern of breathing in betaENaC-Tg mice
-
COI: 1:STN:280:DC%2BC3MjptFKqsA%3D%3D, PID: 21700000
-
Bonora M, Riffault L, Marie S, Mall M, Clement A, Tabary O (2011) Morphological analysis of the trachea and pattern of breathing in betaENaC-Tg mice. Respir Physiol Neurobiol 178:346–348
-
(2011)
Respir Physiol Neurobiol
, vol.178
, pp. 346-348
-
-
Bonora, M.1
Riffault, L.2
Marie, S.3
Mall, M.4
Clement, A.5
Tabary, O.6
-
12
-
-
84974623218
-
Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma
-
PID: 27183390
-
Bonser LR, Zlock L, Finkbeiner W, Erle DJ (2016) Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma. J Clin Invest 126:2367–2371
-
(2016)
J Clin Invest
, vol.126
, pp. 2367-2371
-
-
Bonser, L.R.1
Zlock, L.2
Finkbeiner, W.3
Erle, D.J.4
-
13
-
-
34249662628
-
Cystic fibrosis: a disease of vulnerability to airway surface dehydration
-
COI: 1:CAS:528:DC%2BD2sXmtVGgtLc%3D, PID: 17524805
-
Boucher RC (2007) Cystic fibrosis: a disease of vulnerability to airway surface dehydration. Trends Mol Med 13:231–240
-
(2007)
Trends Mol Med
, vol.13
, pp. 231-240
-
-
Boucher, R.C.1
-
14
-
-
0022973473
-
Na+ transport in cystic fibrosis respiratory epithelia. abnormal basal rate and response to adenylate cyclase activation
-
COI: 1:CAS:528:DyaL28Xmt1eqtrY%3D, PID: 3771796
-
Boucher RC, Stutts MJ, Knowles MR, Cantley L, Gatzy JT (1986) Na+ transport in cystic fibrosis respiratory epithelia. abnormal basal rate and response to adenylate cyclase activation. J Clin Invest 78:1245–1252
-
(1986)
J Clin Invest
, vol.78
, pp. 1245-1252
-
-
Boucher, R.C.1
Stutts, M.J.2
Knowles, M.R.3
Cantley, L.4
Gatzy, J.T.5
-
15
-
-
84865305392
-
A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia
-
COI: 1:CAS:528:DC%2BC38Xht1ahu7nO, PID: 22923574
-
Button B, Cai LH, Ehre C, Kesimer M, Hill DB, Sheehan JK, Boucher RC, Rubinstein M (2012) A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia. Science 337:937–941
-
(2012)
Science
, vol.337
, pp. 937-941
-
-
Button, B.1
Cai, L.H.2
Ehre, C.3
Kesimer, M.4
Hill, D.B.5
Sheehan, J.K.6
Boucher, R.C.7
Rubinstein, M.8
-
16
-
-
84989261241
-
Mucus hyperconcentration as a unifying aspect of the chronic bronchitic phenotype
-
PID: 27115951
-
Button B, Anderson WH, Boucher RC (2016) Mucus hyperconcentration as a unifying aspect of the chronic bronchitic phenotype. Ann Am Thorac Soc 13(Suppl 2):S156–S162
-
(2016)
Ann Am Thorac Soc
, vol.13
, pp. S156-S162
-
-
Button, B.1
Anderson, W.H.2
Boucher, R.C.3
-
17
-
-
80052664252
-
Alternatively activated macrophages and airway disease
-
COI: 1:CAS:528:DC%2BC3MXht12rtb%2FM, PID: 21896520
-
Byers DE, Holtzman MJ (2011) Alternatively activated macrophages and airway disease. Chest 140:768–774
-
(2011)
Chest
, vol.140
, pp. 768-774
-
-
Byers, D.E.1
Holtzman, M.J.2
-
18
-
-
84957848452
-
Pulmonary macrophages: key players in the innate defence of the airways
-
PID: 26286722
-
Byrne AJ, Mathie SA, Gregory LG, Lloyd CM (2015) Pulmonary macrophages: key players in the innate defence of the airways. Thorax 70:1189–1196
-
(2015)
Thorax
, vol.70
, pp. 1189-1196
-
-
Byrne, A.J.1
Mathie, S.A.2
Gregory, L.G.3
Lloyd, C.M.4
-
19
-
-
33646540731
-
Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers
-
COI: 1:CAS:528:DC%2BD28XmslSrsbY%3D, PID: 16497995
-
Cantin AM, Hanrahan JW, Bilodeau G, Ellis L, Dupuis A, Liao J, Zielenski J, Durie P (2006) Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers. Am J Respir Crit Care Med 173:1139–1144
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 1139-1144
-
-
Cantin, A.M.1
Hanrahan, J.W.2
Bilodeau, G.3
Ellis, L.4
Dupuis, A.5
Liao, J.6
Zielenski, J.7
Durie, P.8
-
20
-
-
84937631483
-
Inflammation in cystic fibrosis lung disease: pathogenesis and therapy
-
COI: 1:CAS:528:DC%2BC2MXkvVWjsLY%3D, PID: 25814049
-
Cantin AM, Hartl D, Konstan MW, Chmiel JF (2015) Inflammation in cystic fibrosis lung disease: pathogenesis and therapy. J Cyst Fibros 14:419–430
-
(2015)
J Cyst Fibros
, vol.14
, pp. 419-430
-
-
Cantin, A.M.1
Hartl, D.2
Konstan, M.W.3
Chmiel, J.F.4
-
21
-
-
34447116244
-
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
-
COI: 1:CAS:528:DC%2BD2sXnsFWmtrk%3D, PID: 17572686
-
Chen CJ, Kono H, Golenbock D, Reed G, Akira S, Rock KL (2007) Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med 13:851–856
-
(2007)
Nat Med
, vol.13
, pp. 851-856
-
-
Chen, C.J.1
Kono, H.2
Golenbock, D.3
Reed, G.4
Akira, S.5
Rock, K.L.6
-
22
-
-
84900555408
-
IL-1beta induction of MUC5AC gene expression is mediated by CREB and NF-kappaB and repressed by dexamethasone
-
COI: 1:CAS:528:DC%2BC2cXns1Gkurc%3D, PID: 24487386
-
Chen Y, Garvin LM, Nickola TJ, Watson AM, Colberg-Poley AM, Rose MC (2014) IL-1beta induction of MUC5AC gene expression is mediated by CREB and NF-kappaB and repressed by dexamethasone. Am J Physiol Lung Cell Mol Physiol 306:L797–L807
-
(2014)
Am J Physiol Lung Cell Mol Physiol
, vol.306
, pp. L797-L807
-
-
Chen, Y.1
Garvin, L.M.2
Nickola, T.J.3
Watson, A.M.4
Colberg-Poley, A.M.5
Rose, M.C.6
-
24
-
-
84856557879
-
Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration
-
COI: 1:CAS:528:DC%2BC38XitFOgu7g%3D, PID: 21990373
-
Clunes LA, Davies CM, Coakley RD, Aleksandrov AA, Henderson AG, Zeman KL, Worthington EN, Gentzsch M, Kreda SM, Cholon D, Bennett WD, Riordan JR, Boucher RC, Tarran R (2012) Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration. FASEB J 26:533–545
-
(2012)
FASEB J
, vol.26
, pp. 533-545
-
-
Clunes, L.A.1
Davies, C.M.2
Coakley, R.D.3
Aleksandrov, A.A.4
Henderson, A.G.5
Zeman, K.L.6
Worthington, E.N.7
Gentzsch, M.8
Kreda, S.M.9
Cholon, D.10
Bennett, W.D.11
Riordan, J.R.12
Boucher, R.C.13
Tarran, R.14
-
25
-
-
69249231952
-
Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation
-
COI: 1:CAS:528:DC%2BD1MXpt1OgtL0%3D, PID: 19648933
-
Cobos-Correa A, Trojanek JB, Diemer S, Mall MA, Schultz C (2009) Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation. Nat Chem Biol 5:628–630
-
(2009)
Nat Chem Biol
, vol.5
, pp. 628-630
-
-
Cobos-Correa, A.1
Trojanek, J.B.2
Diemer, S.3
Mall, M.A.4
Schultz, C.5
-
26
-
-
84961933652
-
Progress in therapies for cystic fibrosis
-
PID: 27053340
-
De Boeck K, Amaral MD (2016) Progress in therapies for cystic fibrosis. Lancet Respir Med 4:662–674
-
(2016)
Lancet Respir Med
, vol.4
, pp. 662-674
-
-
De Boeck, K.1
Amaral, M.D.2
-
27
-
-
84864545087
-
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
-
COI: 1:CAS:528:DC%2BC38XhtFWmtrfJ, PID: 22850787
-
Dinarello CA, Simon A, van der Meer JW (2012) Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat Rev Drug Discov 11:633–652
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 633-652
-
-
Dinarello, C.A.1
Simon, A.2
van der Meer, J.W.3
-
28
-
-
34548215173
-
Mucociliary clearance as an outcome measure for cystic fibrosis clinical research
-
PID: 17652507
-
Donaldson SH, Corcoran TE, Laube BL, Bennett WD (2007) Mucociliary clearance as an outcome measure for cystic fibrosis clinical research. Proc Am Thorac Soc 4:399–405
-
(2007)
Proc Am Thorac Soc
, vol.4
, pp. 399-405
-
-
Donaldson, S.H.1
Corcoran, T.E.2
Laube, B.L.3
Bennett, W.D.4
-
29
-
-
84895067804
-
BIIL 284 reduces neutrophil numbers but increases P. aeruginosa bacteremia and inflammation in mouse lungs
-
COI: 1:CAS:528:DC%2BC3sXhslehs77P, PID: 24183915
-
Doring G, Bragonzi A, Paroni M, Akturk FF, Cigana C, Schmidt A, Gilpin D, Heyder S, Born T, Smaczny C, Kohlhaufl M, Wagner TO, Loebinger MR, Bilton D, Tunney MM, Elborn JS, Pier GB, Konstan MW, Ulrich M (2014) BIIL 284 reduces neutrophil numbers but increases P. aeruginosa bacteremia and inflammation in mouse lungs. J Cyst Fibros 13:156–163
-
(2014)
J Cyst Fibros
, vol.13
, pp. 156-163
-
-
Doring, G.1
Bragonzi, A.2
Paroni, M.3
Akturk, F.F.4
Cigana, C.5
Schmidt, A.6
Gilpin, D.7
Heyder, S.8
Born, T.9
Smaczny, C.10
Kohlhaufl, M.11
Wagner, T.O.12
Loebinger, M.R.13
Bilton, D.14
Tunney, M.M.15
Elborn, J.S.16
Pier, G.B.17
Konstan, M.W.18
Ulrich, M.19
-
30
-
-
84881494429
-
Acquired CFTR dysfunction in the lower airways in COPD
-
Dransfield MT, Wilhelm AM, Flanagan B, Courville C, Tidwell SL, Raju SV, Gaggar A, Steele C, Tang LP, Liu B, Rowe SM (2013) Acquired CFTR dysfunction in the lower airways in COPD. Chest 144:498–506
-
(2013)
Chest
, vol.144
, pp. 498-506
-
-
Dransfield, M.T.1
Wilhelm, A.M.2
Flanagan, B.3
Courville, C.4
Tidwell, S.L.5
Raju, S.V.6
Gaggar, A.7
Steele, C.8
Tang, L.P.9
Liu, B.10
Rowe, S.M.11
-
31
-
-
58149234048
-
Mucus hypersecretion in asthma: causes and effects
-
COI: 1:CAS:528:DC%2BD1MXis1OmtQ%3D%3D, PID: 19077699
-
Evans CM, Kim K, Tuvim MJ, Dickey BF (2009) Mucus hypersecretion in asthma: causes and effects. Curr Opin Pulm Med 15:4–11
-
(2009)
Curr Opin Pulm Med
, vol.15
, pp. 4-11
-
-
Evans, C.M.1
Kim, K.2
Tuvim, M.J.3
Dickey, B.F.4
-
32
-
-
84923361939
-
The polymeric mucin Muc5ac is required for allergic airway hyperreactivity
-
COI: 1:CAS:528:DC%2BC2MXhtF2it7vI, PID: 25687754
-
Evans CM, Raclawska DS, Ttofali F, Liptzin DR, Fletcher AA, Harper DN, McGing MA, McElwee MM, Williams OW, Sanchez E, Roy MG, Kindrachuk KN, Wynn TA, Eltzschig HK, Blackburn MR, Tuvim MJ, Janssen WJ, Schwartz DA, Dickey BF (2015) The polymeric mucin Muc5ac is required for allergic airway hyperreactivity. Nat Commun 6:6281
-
(2015)
Nat Commun
, vol.6
, pp. 6281
-
-
Evans, C.M.1
Raclawska, D.S.2
Ttofali, F.3
Liptzin, D.R.4
Fletcher, A.A.5
Harper, D.N.6
McGing, M.A.7
McElwee, M.M.8
Williams, O.W.9
Sanchez, E.10
Roy, M.G.11
Kindrachuk, K.N.12
Wynn, T.A.13
Eltzschig, H.K.14
Blackburn, M.R.15
Tuvim, M.J.16
Janssen, W.J.17
Schwartz, D.A.18
Dickey, B.F.19
-
33
-
-
84925546187
-
Type 2 inflammation in asthma--present in most, absent in many
-
COI: 1:CAS:528:DC%2BC2cXitFKltb7J, PID: 25534623
-
Fahy JV (2015) Type 2 inflammation in asthma--present in most, absent in many. Nat Rev Immunol 15:57–65
-
(2015)
Nat Rev Immunol
, vol.15
, pp. 57-65
-
-
Fahy, J.V.1
-
34
-
-
78649735324
-
Airway mucus function and dysfunction
-
COI: 1:CAS:528:DC%2BC3cXhsFaisrjL, PID: 21121836
-
Fahy JV, Dickey BF (2010) Airway mucus function and dysfunction. N Engl J Med 363:2233–2247
-
(2010)
N Engl J Med
, vol.363
, pp. 2233-2247
-
-
Fahy, J.V.1
Dickey, B.F.2
-
35
-
-
84983227230
-
Inhaled protein/peptide-based therapies for respiratory disease
-
PID: 27098663
-
Fellner RC, Terryah ST, Tarran R (2016) Inhaled protein/peptide-based therapies for respiratory disease. Mol Cell Pediatr 3:16
-
(2016)
Mol Cell Pediatr
, vol.3
, pp. 16
-
-
Fellner, R.C.1
Terryah, S.T.2
Tarran, R.3
-
36
-
-
84927792201
-
Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease
-
COI: 1:CAS:528:DC%2BC2MXntFOktLc%3D, PID: 25607238
-
Fritzsching B, Zhou-Suckow Z, Trojanek JB, Schubert SC, Schatterny J, Hirtz S, Agrawal R, Muley T, Kahn N, Sticht C, Gunkel N, Welte T, Randell SH, Langer F, Schnabel P, Herth FJ, Mall MA (2015) Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease. Am J Respir Crit Care Med 191:902–913
-
(2015)
Am J Respir Crit Care Med
, vol.191
, pp. 902-913
-
-
Fritzsching, B.1
Zhou-Suckow, Z.2
Trojanek, J.B.3
Schubert, S.C.4
Schatterny, J.5
Hirtz, S.6
Agrawal, R.7
Muley, T.8
Kahn, N.9
Sticht, C.10
Gunkel, N.11
Welte, T.12
Randell, S.H.13
Langer, F.14
Schnabel, P.15
Herth, F.J.16
Mall, M.A.17
-
37
-
-
85007597333
-
Impaired mucus clearance exacerbates allergen-induced type 2 airway inflammation in juvenile mice. J Allergy Clin Immunol
-
Fritzsching B, Hagner M, Dai L, Christochowitz S, Agrawal R., Van Bodegom C, Schmidt S, Schatterny J, Hirtz S, Brown R, Goritzka M, Duerr J, Zhou-Suckow Z, Mall MA (2016) Impaired mucus clearance exacerbates allergen-induced type 2 airway inflammation in juvenile mice. J Allergy Clin Immunol. doi: 10.1016/j.jaci.2016.09.045
-
(2016)
doi: 10.1016/j.jaci.2016.09.045
-
-
Fritzsching, B.1
Hagner, M.2
Dai, L.3
Christochowitz, S.4
Agrawal, R.5
Van Bodegom, C.6
Schmidt, S.7
Schatterny, J.8
Hirtz, S.9
Brown, R.10
Goritzka, M.11
Duerr, J.12
Zhou-Suckow, Z.13
Mall, M.A.14
-
38
-
-
80051640917
-
NF-kappaB mediates IL-1beta- and IL-17A-induced MUC5B expression in airway epithelial cells
-
COI: 1:CAS:528:DC%2BC3MXhtVSitrrJ, PID: 20935193
-
Fujisawa T, Chang MM, Velichko S, Thai P, Hung LY, Huang F, Phuong N, Chen Y, Wu R (2011) NF-kappaB mediates IL-1beta- and IL-17A-induced MUC5B expression in airway epithelial cells. Am J Respir Cell Mol Biol 45:246–252
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 246-252
-
-
Fujisawa, T.1
Chang, M.M.2
Velichko, S.3
Thai, P.4
Hung, L.Y.5
Huang, F.6
Phuong, N.7
Chen, Y.8
Wu, R.9
-
39
-
-
80053063761
-
The role of matrix metalloproteinases in cystic fibrosis lung disease
-
COI: 1:CAS:528:DC%2BC3MXhsFals7fJ, PID: 21233269
-
Gaggar A, Hector A, Bratcher PE, Mall MA, Griese M, Hartl D (2011) The role of matrix metalloproteinases in cystic fibrosis lung disease. Eur Respir J 38:721–727
-
(2011)
Eur Respir J
, vol.38
, pp. 721-727
-
-
Gaggar, A.1
Hector, A.2
Bratcher, P.E.3
Mall, M.A.4
Griese, M.5
Hartl, D.6
-
40
-
-
84936792007
-
Genetic deletion and pharmacological inhibition of PI3K gamma reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease
-
PID: 26185363
-
Galluzzo M, Ciraolo E, Lucattelli M, Hoxha E, Ulrich M, Campa CC, Lungarella G, Doring G, Zhou-Suckow Z, Mall M, Hirsch E, De RV (2015) Genetic deletion and pharmacological inhibition of PI3K gamma reduces neutrophilic airway inflammation and lung damage in mice with cystic fibrosis-like lung disease. Mediators Inflamm 2015:545417
-
(2015)
Mediators Inflamm
, vol.2015
, pp. 545417
-
-
Galluzzo, M.1
Ciraolo, E.2
Lucattelli, M.3
Hoxha, E.4
Ulrich, M.5
Campa, C.C.6
Lungarella, G.7
Doring, G.8
Zhou-Suckow, Z.9
Mall, M.10
Hirsch, E.11
De, R.V.12
-
41
-
-
84862663742
-
Spatially resolved monitoring of neutrophil elastase activity with ratiometric fluorescent reporters
-
COI: 1:CAS:528:DC%2BC38XmsFCkt74%3D, PID: 22555935
-
Gehrig S, Mall MA, Schultz C (2012) Spatially resolved monitoring of neutrophil elastase activity with ratiometric fluorescent reporters. Angew Chem Int Ed Engl 51:6258–6261
-
(2012)
Angew Chem Int Ed Engl
, vol.51
, pp. 6258-6261
-
-
Gehrig, S.1
Mall, M.A.2
Schultz, C.3
-
42
-
-
84899791723
-
Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease
-
PID: 24678594
-
Gehrig S, Duerr J, Weitnauer M, Wagner CJ, Graeber SY, Schatterny J, Hirtz S, Belaaouaj A, Dalpke AH, Schultz C, Mall MA (2014) Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease. Am J Respir Crit Care Med 189:1082–1092
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 1082-1092
-
-
Gehrig, S.1
Duerr, J.2
Weitnauer, M.3
Wagner, C.J.4
Graeber, S.Y.5
Schatterny, J.6
Hirtz, S.7
Belaaouaj, A.8
Dalpke, A.H.9
Schultz, C.10
Mall, M.A.11
-
43
-
-
84878002619
-
Cellular uptake and localization of inhaled gold nanoparticles in lungs of mice with chronic obstructive pulmonary disease
-
COI: 1:CAS:528:DC%2BC3sXptlyju74%3D, PID: 23680060
-
Geiser M, Quaile O, Wenk A, Wigge C, Eigeldinger-Berthou S, Hirn S, Schaffler M, Schleh C, Moller W, Mall MA, Kreyling WG (2013) Cellular uptake and localization of inhaled gold nanoparticles in lungs of mice with chronic obstructive pulmonary disease. Part Fibre Toxicol 10:19
-
(2013)
Part Fibre Toxicol
, vol.10
, pp. 19
-
-
Geiser, M.1
Quaile, O.2
Wenk, A.3
Wigge, C.4
Eigeldinger-Berthou, S.5
Hirn, S.6
Schaffler, M.7
Schleh, C.8
Moller, W.9
Mall, M.A.10
Kreyling, W.G.11
-
44
-
-
84904275596
-
Nanoparticle uptake by airway phagocytes after fungal spore challenge in murine allergic asthma and chronic bronchitis
-
PID: 25027175
-
Geiser M, Wigge C, Conrad ML, Eigeldinger-Berthou S, Kunzi L, Garn H, Renz H, Mall MA (2014) Nanoparticle uptake by airway phagocytes after fungal spore challenge in murine allergic asthma and chronic bronchitis. BMC Pulm Med 14:116
-
(2014)
BMC Pulm Med
, vol.14
, pp. 116
-
-
Geiser, M.1
Wigge, C.2
Conrad, M.L.3
Eigeldinger-Berthou, S.4
Kunzi, L.5
Garn, H.6
Renz, H.7
Mall, M.A.8
-
45
-
-
84941423127
-
Airway hydration and COPD
-
COI: 1:CAS:528:DC%2BC2MXhtVWrurnM, PID: 26068443
-
Ghosh A, Boucher RC, Tarran R (2015) Airway hydration and COPD. Cell Mol Life Sci 72:3637–3652
-
(2015)
Cell Mol Life Sci
, vol.72
, pp. 3637-3652
-
-
Ghosh, A.1
Boucher, R.C.2
Tarran, R.3
-
46
-
-
0142043977
-
Pathophysiology and management of pulmonary infections in cystic fibrosis
-
PID: 14555458
-
Gibson RL, Burns JL, Ramsey BW (2003) Pathophysiology and management of pulmonary infections in cystic fibrosis. Am J Respir Crit Care Med 168:918–951
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 918-951
-
-
Gibson, R.L.1
Burns, J.L.2
Ramsey, B.W.3
-
47
-
-
77953268611
-
Alternative activation of macrophages: mechanism and functions
-
COI: 1:CAS:528:DC%2BC3cXnt1Kls78%3D, PID: 20510870
-
Gordon S, Martinez FO (2010) Alternative activation of macrophages: mechanism and functions. Immunity 32:593–604
-
(2010)
Immunity
, vol.32
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
48
-
-
84883480967
-
Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease
-
COI: 1:CAS:528:DC%2BC3sXhtlyqu7vE, PID: 23590312
-
Graeber SY, Zhou-Suckow Z, Schatterny J, Hirtz S, Boucher RC, Mall MA (2013) Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease. Am J Respir Cell Mol Biol 49:410–417
-
(2013)
Am J Respir Cell Mol Biol
, vol.49
, pp. 410-417
-
-
Graeber, S.Y.1
Zhou-Suckow, Z.2
Schatterny, J.3
Hirtz, S.4
Boucher, R.C.5
Mall, M.A.6
-
49
-
-
84864313785
-
Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype
-
COI: 1:CAS:528:DC%2BC38XhtVegtrfE, PID: 22711878
-
Gustafsson JK, Ermund A, Ambort D, Johansson ME, Nilsson HE, Thorell K, Hebert H, Sjovall H, Hansson GC (2012) Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype. J Exp Med 209:1263–1272
-
(2012)
J Exp Med
, vol.209
, pp. 1263-1272
-
-
Gustafsson, J.K.1
Ermund, A.2
Ambort, D.3
Johansson, M.E.4
Nilsson, H.E.5
Thorell, K.6
Hebert, H.7
Sjovall, H.8
Hansson, G.C.9
-
50
-
-
84937690389
-
Barrier epithelial cells and the control of Type 2 immunity
-
COI: 1:CAS:528:DC%2BC2MXht1Kiu7nF, PID: 26200011
-
Hammad H, Lambrecht BN (2015) Barrier epithelial cells and the control of Type 2 immunity. Immunity 43:29–40
-
(2015)
Immunity
, vol.43
, pp. 29-40
-
-
Hammad, H.1
Lambrecht, B.N.2
-
51
-
-
84866182329
-
Innate immunity in cystic fibrosis lung disease
-
COI: 1:CAS:528:DC%2BC38XhtlOjurrP, PID: 22917571
-
Hartl D, Gaggar A, Bruscia E, Hector A, Marcos V, Jung A, Greene C, McElvaney G, Mall M, Doring G (2012) Innate immunity in cystic fibrosis lung disease. J Cyst Fibros 11:363–382
-
(2012)
J Cyst Fibros
, vol.11
, pp. 363-382
-
-
Hartl, D.1
Gaggar, A.2
Bruscia, E.3
Hector, A.4
Marcos, V.5
Jung, A.6
Greene, C.7
McElvaney, G.8
Mall, M.9
Doring, G.10
-
52
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
COI: 1:CAS:528:DyaK2sXmt12qt7Y%3D, PID: 9302297
-
Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD (1997) Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 277:2002–2004
-
(1997)
Science
, vol.277
, pp. 2002-2004
-
-
Hautamaki, R.D.1
Kobayashi, D.K.2
Senior, R.M.3
Shapiro, S.D.4
-
53
-
-
0037627873
-
The role of mucus in fatal asthma
-
PID: 12867239
-
Hays SR, Fahy JV (2003) The role of mucus in fatal asthma. Am J Med 115:68–69
-
(2003)
Am J Med
, vol.115
, pp. 68-69
-
-
Hays, S.R.1
Fahy, J.V.2
-
54
-
-
80052955294
-
The Chitinase-like protein YKL-40 modulates cystic fibrosis lung disease
-
COI: 1:CAS:528:DC%2BC3MXht12ns7rP, PID: 21949714
-
Hector A, Kormann MS, Mack I, Latzin P, Casaulta C, Kieninger E, Zhou Z, Yildirim AO, Bohla A, Rieber N, Kappler M, Koller B, Eber E, Eickmeier O, Zielen S, Eickelberg O, Griese M, Mall MA, Hartl D (2011) The Chitinase-like protein YKL-40 modulates cystic fibrosis lung disease. PLoS ONE 6:e24399
-
(2011)
PLoS ONE
, vol.6
-
-
Hector, A.1
Kormann, M.S.2
Mack, I.3
Latzin, P.4
Casaulta, C.5
Kieninger, E.6
Zhou, Z.7
Yildirim, A.O.8
Bohla, A.9
Rieber, N.10
Kappler, M.11
Koller, B.12
Eber, E.13
Eickmeier, O.14
Zielen, S.15
Eickelberg, O.16
Griese, M.17
Mall, M.A.18
Hartl, D.19
-
55
-
-
84903759350
-
Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure
-
COI: 1:CAS:528:DC%2BC2cXhtFOht77F, PID: 24892808
-
Henderson AG, Ehre C, Button B, Abdullah LH, Cai LH, Leigh MW, DeMaria GC, Matsui H, Donaldson SH, Davis CW, Sheehan JK, Boucher RC, Kesimer M (2014) Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure. J Clin Invest 124:3047–3060
-
(2014)
J Clin Invest
, vol.124
, pp. 3047-3060
-
-
Henderson, A.G.1
Ehre, C.2
Button, B.3
Abdullah, L.H.4
Cai, L.H.5
Leigh, M.W.6
DeMaria, G.C.7
Matsui, H.8
Donaldson, S.H.9
Davis, C.W.10
Sheehan, J.K.11
Boucher, R.C.12
Kesimer, M.13
-
56
-
-
84926500091
-
The innate immune function of airway epithelial cells in inflammatory lung disease
-
COI: 1:CAS:528:DC%2BC2MXntlWhtLs%3D, PID: 25700381
-
Hiemstra PS, McCray PB Jr, Bals R (2015) The innate immune function of airway epithelial cells in inflammatory lung disease. Eur Respir J 45:1150–1162
-
(2015)
Eur Respir J
, vol.45
, pp. 1150-1162
-
-
Hiemstra, P.S.1
McCray, P.B.2
Bals, R.3
-
57
-
-
84906089250
-
Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis
-
COI: 1:CAS:528:DC%2BC2cXhtlejtL7J, PID: 25124441
-
Hoegger MJ, Fischer AJ, McMenimen JD, Ostedgaard LS, Tucker AJ, Awadalla MA, Moninger TO, Michalski AS, Hoffman EA, Zabner J, Stoltz DA, Welsh MJ (2014) Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis. Science 345:818–822
-
(2014)
Science
, vol.345
, pp. 818-822
-
-
Hoegger, M.J.1
Fischer, A.J.2
McMenimen, J.D.3
Ostedgaard, L.S.4
Tucker, A.J.5
Awadalla, M.A.6
Moninger, T.O.7
Michalski, A.S.8
Hoffman, E.A.9
Zabner, J.10
Stoltz, D.A.11
Welsh, M.J.12
-
58
-
-
4344675455
-
Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
-
PID: 15325838
-
Hogg JC (2004) Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 364:709–721
-
(2004)
Lancet
, vol.364
, pp. 709-721
-
-
Hogg, J.C.1
-
59
-
-
66149093072
-
The pathology of chronic obstructive pulmonary disease
-
COI: 1:CAS:528:DC%2BD1MXis1ahsr0%3D, PID: 18954287
-
Hogg JC, Timens W (2009) The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol 4:435–459
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 435-459
-
-
Hogg, J.C.1
Timens, W.2
-
60
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
COI: 1:CAS:528:DC%2BD2cXltFGgur4%3D, PID: 15215480
-
Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO, Pare PD (2004) The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 350:2645–2653
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
Woods, R.4
Elliott, W.M.5
Buzatu, L.6
Cherniack, R.M.7
Rogers, R.M.8
Sciurba, F.C.9
Coxson, H.O.10
Pare, P.D.11
-
61
-
-
0032864037
-
Effects of drugs on mucus clearance
-
COI: 1:CAS:528:DyaK1MXmslGhtbw%3D, PID: 10515429
-
Houtmeyers E, Gosselink R, Gayan-Ramirez G, Decramer M (1999) Effects of drugs on mucus clearance. Eur Respir J 14:452–467
-
(1999)
Eur Respir J
, vol.14
, pp. 452-467
-
-
Houtmeyers, E.1
Gosselink, R.2
Gayan-Ramirez, G.3
Decramer, M.4
-
62
-
-
84895076669
-
FRET-based and other fluorescent proteinase probes
-
COI: 1:CAS:528:DC%2BC2cXht1ygs7Y%3D, PID: 24464820
-
Hu HY, Gehrig S, Reither G, Subramanian D, Mall MA, Plettenburg O, Schultz C (2014) FRET-based and other fluorescent proteinase probes. Biotechnol J 9:266–281
-
(2014)
Biotechnol J
, vol.9
, pp. 266-281
-
-
Hu, H.Y.1
Gehrig, S.2
Reither, G.3
Subramanian, D.4
Mall, M.A.5
Plettenburg, O.6
Schultz, C.7
-
63
-
-
84905451913
-
Lung arginase expression and activity is increased in cystic fibrosis mouse models
-
PID: 24925982
-
Jaecklin T, Duerr J, Huang H, Rafii M, Bear CE, Ratjen F, Pencharz P, Kavanagh BP, Mall MA, Grasemann H (2014) Lung arginase expression and activity is increased in cystic fibrosis mouse models. J Appl Physiol 117(1985):284–288
-
(2014)
J Appl Physiol
, vol.117
, Issue.1985
, pp. 284-288
-
-
Jaecklin, T.1
Duerr, J.2
Huang, H.3
Rafii, M.4
Bear, C.E.5
Ratjen, F.6
Pencharz, P.7
Kavanagh, B.P.8
Mall, M.A.9
Grasemann, H.10
-
64
-
-
84990061986
-
Control of lung defence by mucins and macrophages: ancient defence mechanisms with modern functions
-
PID: 27587549
-
Janssen WJ, Stefanski AL, Bochner BS, Evans CM (2016) Control of lung defence by mucins and macrophages: ancient defence mechanisms with modern functions. Eur Respir J 48:1201–1214
-
(2016)
Eur Respir J
, vol.48
, pp. 1201-1214
-
-
Janssen, W.J.1
Stefanski, A.L.2
Bochner, B.S.3
Evans, C.M.4
-
65
-
-
84986594029
-
Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice
-
PID: 27448665
-
Jia J, Conlon TM, Ballester LC, Seimetz M, Bednorz M, Zhou-Suckow Z, Weissmann N, Eickelberg O, Mall MA, Yildirim AO (2016) Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice. Am J Physiol Lung Cell Mol Physiol 311:L602–L610
-
(2016)
Am J Physiol Lung Cell Mol Physiol
, vol.311
, pp. L602-L610
-
-
Jia, J.1
Conlon, T.M.2
Ballester, L.C.3
Seimetz, M.4
Bednorz, M.5
Zhou-Suckow, Z.6
Weissmann, N.7
Eickelberg, O.8
Mall, M.A.9
Yildirim, A.O.10
-
66
-
-
84866627429
-
CFTR regulates early pathogenesis of chronic obstructive lung disease in bENaC-overexpressing mice
-
COI: 1:CAS:528:DC%2BC38Xht1Oit77N, PID: 22937152
-
Johannesson B, Hirtz S, Schatterny J, Schultz C, Mall MA (2012) CFTR regulates early pathogenesis of chronic obstructive lung disease in bENaC-overexpressing mice. PLoS ONE 7:e44059
-
(2012)
PLoS ONE
, vol.7
-
-
Johannesson, B.1
Hirtz, S.2
Schatterny, J.3
Schultz, C.4
Mall, M.A.5
-
67
-
-
0036194724
-
Mucus clearance as a primary innate defense mechanism for mammalian airways
-
COI: 1:CAS:528:DC%2BD38XitVeqt78%3D, PID: 11877463
-
Knowles MR, Boucher RC (2002) Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest 109:571–577
-
(2002)
J Clin Invest
, vol.109
, pp. 571-577
-
-
Knowles, M.R.1
Boucher, R.C.2
-
68
-
-
84922723245
-
Detrimental effects of secondhand smoke exposure on infants with cystic fibrosis
-
PID: 24610820
-
Kopp BT, Sarzynski L, Khalfoun S, Hayes D Jr, Thompson R, Nicholson L, Long F, Castile R, Groner J (2015) Detrimental effects of secondhand smoke exposure on infants with cystic fibrosis. Pediatr Pulmonol 50:25–34
-
(2015)
Pediatr Pulmonol
, vol.50
, pp. 25-34
-
-
Kopp, B.T.1
Sarzynski, L.2
Khalfoun, S.3
Hayes, D.4
Thompson, R.5
Nicholson, L.6
Long, F.7
Castile, R.8
Groner, J.9
-
69
-
-
0037812532
-
Characterization of airway plugging in fatal asthma
-
PID: 12867228
-
Kuyper LM, Pare PD, Hogg JC, Lambert RK, Ionescu D, Woods R, Bai TR (2003) Characterization of airway plugging in fatal asthma. Am J Med 115:6–11
-
(2003)
Am J Med
, vol.115
, pp. 6-11
-
-
Kuyper, L.M.1
Pare, P.D.2
Hogg, J.C.3
Lambert, R.K.4
Ionescu, D.5
Woods, R.6
Bai, T.R.7
-
71
-
-
63449132488
-
Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung
-
COI: 1:CAS:528:DC%2BD1MXktV2isb8%3D, PID: 19249085
-
Lewis CC, Aronow B, Hutton J, Santeliz J, Dienger K, Herman N, Finkelman FD, Wills-Karp M (2009) Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung. J Allergy Clin Immunol 123:795–804
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 795-804
-
-
Lewis, C.C.1
Aronow, B.2
Hutton, J.3
Santeliz, J.4
Dienger, K.5
Herman, N.6
Finkelman, F.D.7
Wills-Karp, M.8
-
72
-
-
64249168940
-
Airway and lung pathology due to mucosal surface dehydration in b-epithelial Na + channel-overexpressing mice: role of TNF-a and IL-4Ra signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment
-
COI: 1:CAS:528:DC%2BD1MXjsVSju78%3D, PID: 19299736
-
Livraghi A, Grubb BR, Hudson EJ, Wilkinson KJ, Sheehan JK, Mall MA, O’Neal WK, Boucher RC, Randell SH (2009) Airway and lung pathology due to mucosal surface dehydration in b-epithelial Na + channel-overexpressing mice: role of TNF-a and IL-4Ra signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment. J Immunol 182:4357–4367
-
(2009)
J Immunol
, vol.182
, pp. 4357-4367
-
-
Livraghi, A.1
Grubb, B.R.2
Hudson, E.J.3
Wilkinson, K.J.4
Sheehan, J.K.5
Mall, M.A.6
O’Neal, W.K.7
Boucher, R.C.8
Randell, S.H.9
-
73
-
-
84864849180
-
Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation
-
COI: 1:CAS:528:DC%2BC38XjtlOkurg%3D, PID: 22419116
-
Livraghi-Butrico A, Kelly EJ, Klem ER, Dang H, Wolfgang MC, Boucher RC, Randell SH, O’Neal WK (2012) Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation. Mucosal Immunol 5:397–408
-
(2012)
Mucosal Immunol
, vol.5
, pp. 397-408
-
-
Livraghi-Butrico, A.1
Kelly, E.J.2
Klem, E.R.3
Dang, H.4
Wolfgang, M.C.5
Boucher, R.C.6
Randell, S.H.7
O’Neal, W.K.8
-
74
-
-
85013360799
-
-
Livraghi-Butrico A, Grubb BR, Wilkinson KJ, Volmer AS, Burns KA, Evans CM, O’Neal WK, Boucher RC Mucosal Immunol (in press)
-
Livraghi-Butrico A, Grubb BR, Wilkinson KJ, Volmer AS, Burns KA, Evans CM, O’Neal WK, Boucher RC (2016) Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease. Mucosal Immunol (in press)
-
(2016)
Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.
-
-
-
75
-
-
84922974563
-
Epithelial cytokines and pulmonary allergic inflammation
-
COI: 1:CAS:528:DC%2BC2MXisleqt7Y%3D, PID: 25705788
-
Lloyd CM, Saglani S (2015) Epithelial cytokines and pulmonary allergic inflammation. Curr Opin Immunol 34:52–58. doi:10.1016/j.coi.2015.02.001
-
(2015)
Curr Opin Immunol
, vol.34
, pp. 52-58
-
-
Lloyd, C.M.1
Saglani, S.2
-
76
-
-
84969785021
-
Pseudomonas infection and mucociliary and absorptive clearance in the cystic fibrosis lung
-
PID: 27009167
-
Locke LW, Myerburg MM, Weiner DJ, Markovetz MR, Parker RS, Muthukrishnan A, Weber L, Czachowski MR, Lacy RT, Pilewski JM, Corcoran TE (2016) Pseudomonas infection and mucociliary and absorptive clearance in the cystic fibrosis lung. Eur Respir J 47:1392–1401
-
(2016)
Eur Respir J
, vol.47
, pp. 1392-1401
-
-
Locke, L.W.1
Myerburg, M.M.2
Weiner, D.J.3
Markovetz, M.R.4
Parker, R.S.5
Muthukrishnan, A.6
Weber, L.7
Czachowski, M.R.8
Lacy, R.T.9
Pilewski, J.M.10
Corcoran, T.E.11
-
77
-
-
0037134440
-
Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9
-
COI: 1:CAS:528:DC%2BD38XjsFWntbY%3D, PID: 11834742
-
Lohi H, Kujala M, Makela S, Lehtonen E, Kestila M, Saarialho-Kere U, Markovich D, Kere J (2002) Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9. J Biol Chem 277:14246–14254
-
(2002)
J Biol Chem
, vol.277
, pp. 14246-14254
-
-
Lohi, H.1
Kujala, M.2
Makela, S.3
Lehtonen, E.4
Kestila, M.5
Saarialho-Kere, U.6
Markovich, D.7
Kere, J.8
-
78
-
-
84874206379
-
IL-1 family cytokines trigger sterile inflammatory disease
-
PID: 23087690
-
Lukens JR, Gross JM, Kanneganti TD (2012) IL-1 family cytokines trigger sterile inflammatory disease. Front Immunol 3:315
-
(2012)
Front Immunol
, vol.3
, pp. 315
-
-
Lukens, J.R.1
Gross, J.M.2
Kanneganti, T.D.3
-
79
-
-
84991007788
-
The role of chitin, chitinases, and chitinase-like proteins in pediatric lung diseases
-
PID: 26542293
-
Mack I, Hector A, Ballbach M, Kohlhaufl J, Fuchs KJ, Weber A, Mall MA, Hartl D (2015) The role of chitin, chitinases, and chitinase-like proteins in pediatric lung diseases. Mol Cell Pediatr 2:3–0014
-
(2015)
Mol Cell Pediatr
, vol.2
, pp. 3-0014
-
-
Mack, I.1
Hector, A.2
Ballbach, M.3
Kohlhaufl, J.4
Fuchs, K.J.5
Weber, A.6
Mall, M.A.7
Hartl, D.8
-
80
-
-
0028891783
-
Apoptosis, oncosis, and necrosis. an overview of cell death
-
COI: 1:STN:280:DyaK2M7mtVWiug%3D%3D, PID: 7856735
-
Majno G, Joris I (1995) Apoptosis, oncosis, and necrosis. an overview of cell death. Am J Pathol 146:3–15
-
(1995)
Am J Pathol
, vol.146
, pp. 3-15
-
-
Majno, G.1
Joris, I.2
-
81
-
-
45949094270
-
Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models
-
COI: 1:CAS:528:DC%2BD1cXjvFeiu7c%3D, PID: 18518828
-
Mall MA (2008) Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models. J Aerosol Med Pulm Drug Deliv 21:13–24
-
(2008)
J Aerosol Med Pulm Drug Deliv
, vol.21
, pp. 13-24
-
-
Mall, M.A.1
-
82
-
-
58449116969
-
Role of the amiloride-sensitive epithelial Na + channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease
-
COI: 1:CAS:528:DC%2BD1MXivVCqtL8%3D, PID: 19060118
-
Mall MA (2009) Role of the amiloride-sensitive epithelial Na + channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease. Exp Physiol 94:171–174
-
(2009)
Exp Physiol
, vol.94
, pp. 171-174
-
-
Mall, M.A.1
-
83
-
-
84989221545
-
Unplugging mucus in cystic fibrosis and chronic obstructive pulmonary disease
-
PID: 27115954
-
Mall MA (2016) Unplugging mucus in cystic fibrosis and chronic obstructive pulmonary disease. Ann Am Thorac Soc 13(Suppl 2):S177–S185. doi:10.1513/AnnalsATS.201509-641KV.:S177-S185
-
(2016)
Ann Am Thorac Soc
, vol.13
, pp. S177-S185
-
-
Mall, M.A.1
-
84
-
-
84940962718
-
Targeting ion channels in cystic fibrosis
-
COI: 1:CAS:528:DC%2BC2MXhtVKmtL%2FM, PID: 26115565
-
Mall MA, Galietta LJ (2015) Targeting ion channels in cystic fibrosis. J Cyst Fibros 14:561–570
-
(2015)
J Cyst Fibros
, vol.14
, pp. 561-570
-
-
Mall, M.A.1
Galietta, L.J.2
-
85
-
-
84905655597
-
CFTR: cystic fibrosis and beyond
-
COI: 1:CAS:528:DC%2BC2cXitFSitbfO, PID: 24925916
-
Mall MA, Hartl D (2014) CFTR: cystic fibrosis and beyond. Eur Respir J 44:1042–1054
-
(2014)
Eur Respir J
, vol.44
, pp. 1042-1054
-
-
Mall, M.A.1
Hartl, D.2
-
88
-
-
41749115751
-
+ channel-overexpressing mice
-
COI: 1:CAS:528:DC%2BD1cXltFCksLo%3D, PID: 18079494
-
+ channel-overexpressing mice. Am J Respir Crit Care Med 177:730–742
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 730-742
-
-
Mall, M.A.1
Harkema, J.R.2
Trojanek, J.B.3
Treis, D.4
Livraghi, A.5
Schubert, S.6
Zhou, Z.7
Kreda, S.M.8
Tilley, S.L.9
Hudson, E.J.10
O’Neal, W.K.11
Boucher, R.C.12
-
89
-
-
77956240072
-
Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice
-
COI: 1:CAS:528:DC%2BC3cXhtVKhs73M, PID: 20566636
-
Mall MA, Button B, Johannesson B, Zhou Z, Livraghi A, Caldwell RA, Schubert SC, Schultz C, O’Neal WK, Pradervand S, Hummler E, Rossier BC, Grubb BR, Boucher RC (2010) Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice. J Biol Chem 285:26945–26955
-
(2010)
J Biol Chem
, vol.285
, pp. 26945-26955
-
-
Mall, M.A.1
Button, B.2
Johannesson, B.3
Zhou, Z.4
Livraghi, A.5
Caldwell, R.A.6
Schubert, S.C.7
Schultz, C.8
O’Neal, W.K.9
Pradervand, S.10
Hummler, E.11
Rossier, B.C.12
Grubb, B.R.13
Boucher, R.C.14
-
90
-
-
84901610159
-
Early cystic fibrosis lung disease: role of airway surface dehydration and lessons from preventive rehydration therapies in mice
-
Mall MA, Graeber SY, Stahl M, Zhou-Suckow Z (2014) Early cystic fibrosis lung disease: role of airway surface dehydration and lessons from preventive rehydration therapies in mice. Int J Biochem Cell Biol 52:174–179
-
(2014)
Int J Biochem Cell Biol
, vol.52
, pp. 174-179
-
-
Mall, M.A.1
Graeber, S.Y.2
Stahl, M.3
Zhou-Suckow, Z.4
-
91
-
-
84988451817
-
Early detection and sensitive monitoring of CF lung disease: prospects of improved and safer imaging
-
PID: 27662104
-
Mall MA, Stahl M, Graeber SY, Sommerburg O, Kauczor HU, Wielputz MO (2016) Early detection and sensitive monitoring of CF lung disease: prospects of improved and safer imaging. Pediatr Pulmonol 51:S49–S60
-
(2016)
Pediatr Pulmonol
, vol.51
, pp. S49-S60
-
-
Mall, M.A.1
Stahl, M.2
Graeber, S.Y.3
Sommerburg, O.4
Kauczor, H.U.5
Wielputz, M.O.6
-
92
-
-
84928255176
-
Free DNA in cystic fibrosis airway fluids correlates with airflow obstruction
-
PID: 25918476
-
Marcos V, Zhou-Suckow Z, Onder YA, Bohla A, Hector A, Vitkov L, Krautgartner WD, Stoiber W, Griese M, Eickelberg O, Mall MA, Hartl D (2015) Free DNA in cystic fibrosis airway fluids correlates with airflow obstruction. Mediators Inflamm 2015:408935
-
(2015)
Mediators Inflamm
, vol.2015
, pp. 408935
-
-
Marcos, V.1
Zhou-Suckow, Z.2
Onder, Y.A.3
Bohla, A.4
Hector, A.5
Vitkov, L.6
Krautgartner, W.D.7
Stoiber, W.8
Griese, M.9
Eickelberg, O.10
Mall, M.A.11
Hartl, D.12
-
93
-
-
84989821491
-
The role of neutrophils in Alpha-1 antitrypsin deficiency
-
PID: 27564664
-
McCarthy C, Reeves EP, McElvaney NG (2016) The role of neutrophils in Alpha-1 antitrypsin deficiency. Ann Am Thorac Soc 13(Suppl 4):S297–S304
-
(2016)
Ann Am Thorac Soc
, vol.13
, pp. S297-S304
-
-
McCarthy, C.1
Reeves, E.P.2
McElvaney, N.G.3
-
94
-
-
0021908098
-
Tracheobronchial mucociliary clearance in asthma: impairment during remission
-
COI: 1:STN:280:DyaL2M7mvVyktA%3D%3D, PID: 3983883
-
Pavia D, Bateman JR, Sheahan NF, Agnew JE, Clarke SW (1985) Tracheobronchial mucociliary clearance in asthma: impairment during remission. Thorax 40:171–175
-
(1985)
Thorax
, vol.40
, pp. 171-175
-
-
Pavia, D.1
Bateman, J.R.2
Sheahan, N.F.3
Agnew, J.E.4
Clarke, S.W.5
-
95
-
-
48149090717
-
Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis
-
COI: 1:CAS:528:DC%2BD1cXpt1Gqtb4%3D, PID: 18675692
-
Quinton PM (2008) Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis. Lancet 372:415–417
-
(2008)
Lancet
, vol.372
, pp. 415-417
-
-
Quinton, P.M.1
-
96
-
-
85026277078
-
Mucins and their sugars. critical mediators of hyperreactivity and inflammation
-
PID: 27027967
-
Raclawska DS, Ttofali F, Fletcher AA, Harper DN, Bochner BS, Janssen WJ, Evans CM (2016) Mucins and their sugars. critical mediators of hyperreactivity and inflammation. Ann Am Thorac Soc 13(Suppl 1):S98–S99
-
(2016)
Ann Am Thorac Soc
, vol.13
, pp. S98-S99
-
-
Raclawska, D.S.1
Ttofali, F.2
Fletcher, A.A.3
Harper, D.N.4
Bochner, B.S.5
Janssen, W.J.6
Evans, C.M.7
-
97
-
-
0028343344
-
Mucociliary clearance in patients with cystic fibrosis and in normal subjects
-
COI: 1:STN:280:DyaK2c3pslyltA%3D%3D, PID: 8025774
-
Regnis JA, Robinson M, Bailey DL, Cook P, Hooper P, Chan HK, Gonda I, Bautovich G, Bye PT (1994) Mucociliary clearance in patients with cystic fibrosis and in normal subjects. Am J Respir Crit Care Med 150:66–71
-
(1994)
Am J Respir Crit Care Med
, vol.150
, pp. 66-71
-
-
Regnis, J.A.1
Robinson, M.2
Bailey, D.L.3
Cook, P.4
Hooper, P.5
Chan, H.K.6
Gonda, I.7
Bautovich, G.8
Bye, P.T.9
-
98
-
-
33644620356
-
Respiratory tract mucin genes and mucin glycoproteins in health and disease
-
COI: 1:CAS:528:DC%2BD28XhtlKntr8%3D, PID: 16371599
-
Rose MC, Voynow JA (2006) Respiratory tract mucin genes and mucin glycoproteins in health and disease. Physiol Rev 86:245–278
-
(2006)
Physiol Rev
, vol.86
, pp. 245-278
-
-
Rose, M.C.1
Voynow, J.A.2
-
99
-
-
84895535623
-
Lung clearance index is a repeatable and sensitive indicator of radiological changes in bronchiectasis
-
PID: 24428575
-
Rowan SA, Bradley JM, Bradbury I, Lawson J, Lynch T, Gustafsson P, Horsley A, O’Neill K, Ennis M, Elborn JS (2014) Lung clearance index is a repeatable and sensitive indicator of radiological changes in bronchiectasis. Am J Respir Crit Care Med 189:586–592
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 586-592
-
-
Rowan, S.A.1
Bradley, J.M.2
Bradbury, I.3
Lawson, J.4
Lynch, T.5
Gustafsson, P.6
Horsley, A.7
O’Neill, K.8
Ennis, M.9
Elborn, J.S.10
-
100
-
-
84892563951
-
Muc5b is required for airway defence
-
COI: 1:CAS:528:DC%2BC2cXotFGluw%3D%3D, PID: 24317696
-
Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O’Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM (2014) Muc5b is required for airway defence. Nature 505:412–416
-
(2014)
Nature
, vol.505
, pp. 412-416
-
-
Roy, M.G.1
Livraghi-Butrico, A.2
Fletcher, A.A.3
McElwee, M.M.4
Evans, S.E.5
Boerner, R.M.6
Alexander, S.N.7
Bellinghausen, L.K.8
Song, A.S.9
Petrova, Y.M.10
Tuvim, M.J.11
Adachi, R.12
Romo, I.13
Bordt, A.S.14
Bowden, M.G.15
Sisson, J.H.16
Woodruff, P.G.17
Thornton, D.J.18
Rousseau, K.19
De la Garza, M.M.20
Moghaddam, S.J.21
Karmouty-Quintana, H.22
Blackburn, M.R.23
Drouin, S.M.24
Davis, C.W.25
Terrell, K.A.26
Grubb, B.R.27
O’Neal, W.K.28
Flores, S.C.29
Cota-Gomez, A.30
Lozupone, C.A.31
Donnelly, J.M.32
Watson, A.M.33
Hennessy, C.E.34
Keith, R.C.35
Yang, I.V.36
Barthel, L.37
Henson, P.M.38
Janssen, W.J.39
Schwartz, D.A.40
Boucher, R.C.41
Dickey, B.F.42
Evans, C.M.43
more..
-
101
-
-
84868296268
-
Sputum biomarkers of inflammation and lung function decline in children with cystic fibrosis
-
COI: 1:CAS:528:DC%2BC38XhvVynsbjF, PID: 22904182
-
Sagel SD, Wagner BD, Anthony MM, Emmett P, Zemanick ET (2012) Sputum biomarkers of inflammation and lung function decline in children with cystic fibrosis. Am J Respir Crit Care Med 186:857–865
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 857-865
-
-
Sagel, S.D.1
Wagner, B.D.2
Anthony, M.M.3
Emmett, P.4
Zemanick, E.T.5
-
102
-
-
69449097370
-
Pathophysiological features of asthma develop in parallel in house dust mite-exposed neonatal mice
-
COI: 1:CAS:528:DC%2BD1MXhtVyitbfK, PID: 19151316
-
Saglani S, Mathie SA, Gregory LG, Bell MJ, Bush A, Lloyd CM (2009) Pathophysiological features of asthma develop in parallel in house dust mite-exposed neonatal mice. Am J Respir Cell Mol Biol 41:281–289
-
(2009)
Am J Respir Cell Mol Biol
, vol.41
, pp. 281-289
-
-
Saglani, S.1
Mathie, S.A.2
Gregory, L.G.3
Bell, M.J.4
Bush, A.5
Lloyd, C.M.6
-
103
-
-
84908073532
-
Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration
-
PID: 25204199
-
Saini Y, Dang H, Livraghi-Butrico A, Kelly EJ, Jones LC, O’Neal WK, Boucher RC (2014) Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration. BMC Genomics 15:726
-
(2014)
BMC Genomics
, vol.15
, pp. 726
-
-
Saini, Y.1
Dang, H.2
Livraghi-Butrico, A.3
Kelly, E.J.4
Jones, L.C.5
O’Neal, W.K.6
Boucher, R.C.7
-
104
-
-
84963811866
-
Neonatal pulmonary macrophage depletion coupled to defective mucus clearance increases susceptibility to pneumonia and alters pulmonary immune responses
-
Saini Y, Wilkinson KJ, Terrell KA, Burns KA, Livraghi-Butrico A, Doerschuk CM, O’Neal WK, Boucher RC (2015) Neonatal pulmonary macrophage depletion coupled to defective mucus clearance increases susceptibility to pneumonia and alters pulmonary immune responses. Am J Respir Cell Mol Biol 54:210–221
-
(2015)
Am J Respir Cell Mol Biol
, vol.54
, pp. 210-221
-
-
Saini, Y.1
Wilkinson, K.J.2
Terrell, K.A.3
Burns, K.A.4
Livraghi-Butrico, A.5
Doerschuk, C.M.6
O’Neal, W.K.7
Boucher, R.C.8
-
105
-
-
84984662478
-
Generation and functional characterization of epithelial cells with stable expression of SLC26A9 Cl- channels
-
PID: 26801567
-
Salomon JJ, Spahn S, Wang X, Fullekrug J, Bertrand CA, Mall MA (2016) Generation and functional characterization of epithelial cells with stable expression of SLC26A9 Cl- channels. Am J Physiol Lung Cell Mol Physiol 310:L593–L602
-
(2016)
Am J Physiol Lung Cell Mol Physiol
, vol.310
, pp. L593-L602
-
-
Salomon, J.J.1
Spahn, S.2
Wang, X.3
Fullekrug, J.4
Bertrand, C.A.5
Mall, M.A.6
-
106
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
COI: 1:CAS:528:DC%2BD2MXht12msr7K, PID: 16286016
-
Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, McClanahan TK, Zurawski G, Moshrefi M, Qin J, Li X, Gorman DM, Bazan JF, Kastelein RA (2005) IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23:479–490
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
Song, Y.4
Murphy, E.5
McClanahan, T.K.6
Zurawski, G.7
Moshrefi, M.8
Qin, J.9
Li, X.10
Gorman, D.M.11
Bazan, J.F.12
Kastelein, R.A.13
-
107
-
-
84936110996
-
Airway surface dehydration aggravates cigarette smoke-induced hallmarks of COPD in mice
-
PID: 26066648
-
Seys LJ, Verhamme FM, Dupont LL, Desauter E, Duerr J, Seyhan AA, Conickx G, Joos GF, Brusselle GG, Mall MA, Bracke KR (2015) Airway surface dehydration aggravates cigarette smoke-induced hallmarks of COPD in mice. PLoS ONE 10:e0129897
-
(2015)
PLoS ONE
, vol.10
-
-
Seys, L.J.1
Verhamme, F.M.2
Dupont, L.L.3
Desauter, E.4
Duerr, J.5
Seyhan, A.A.6
Conickx, G.7
Joos, G.F.8
Brusselle, G.G.9
Mall, M.A.10
Bracke, K.R.11
-
108
-
-
0029911694
-
Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice
-
COI: 1:CAS:528:DyaK28XivVKrtL0%3D, PID: 8632994
-
Shipley JM, Wesselschmidt RL, Kobayashi DK, Ley TJ, Shapiro SD (1996) Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice. Proc Natl Acad Sci U S A 93:3942–3946
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 3942-3946
-
-
Shipley, J.M.1
Wesselschmidt, R.L.2
Kobayashi, D.K.3
Ley, T.J.4
Shapiro, S.D.5
-
109
-
-
67650712233
-
Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening
-
PID: 19372250
-
Sly PD, Brennan S, Gangell C, de Klerk N, Murray C, Mott L, Stick SM, Robinson PJ, Robertson CF, Ranganathan SC (2009) Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening. Am J Respir Crit Care Med 180:146–152
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 146-152
-
-
Sly, P.D.1
Brennan, S.2
Gangell, C.3
de Klerk, N.4
Murray, C.5
Mott, L.6
Stick, S.M.7
Robinson, P.J.8
Robertson, C.F.9
Ranganathan, S.C.10
-
110
-
-
84878000440
-
Risk factors for bronchiectasis in children with cystic fibrosis
-
COI: 1:CAS:528:DC%2BC3sXhtVOgsL7N, PID: 23692169
-
Sly PD, Gangell CL, Chen L, Ware RS, Ranganathan S, Mott LS, Murray CP, Stick SM (2013) Risk factors for bronchiectasis in children with cystic fibrosis. N Engl J Med 368:1963–1970
-
(2013)
N Engl J Med
, vol.368
, pp. 1963-1970
-
-
Sly, P.D.1
Gangell, C.L.2
Chen, L.3
Ware, R.S.4
Ranganathan, S.5
Mott, L.S.6
Murray, C.P.7
Stick, S.M.8
-
111
-
-
0027210915
-
Regional impairment of mucociliary clearance in chronic obstructive pulmonary disease
-
COI: 1:STN:280:DyaK3s3ltFymsw%3D%3D, PID: 8486016
-
Smaldone GC, Foster WM, O’Riordan TG, Messina MS, Perry RJ, Langenback EG (1993) Regional impairment of mucociliary clearance in chronic obstructive pulmonary disease. Chest 103:1390–1396
-
(1993)
Chest
, vol.103
, pp. 1390-1396
-
-
Smaldone, G.C.1
Foster, W.M.2
O’Riordan, T.G.3
Messina, M.S.4
Perry, R.J.5
Langenback, E.G.6
-
112
-
-
84946887369
-
Tobacco smoke exposure and respiratory morbidity in young children
-
Snodgrass AM, Tan PT, Soh SE, Goh A, Shek LP, van Bever HP, Gluckman PD, Godfrey KM, Chong YS, Saw SM, Kwek K, Teoh OH (2015) Tobacco smoke exposure and respiratory morbidity in young children. Tob Control 25(e2):e75–e82
-
(2015)
Tob Control
, vol.25
, Issue.e2
, pp. e75-e82
-
-
Snodgrass, A.M.1
Tan, P.T.2
Soh, S.E.3
Goh, A.4
Shek, L.P.5
van Bever, H.P.6
Gluckman, P.D.7
Godfrey, K.M.8
Chong, Y.S.9
Saw, S.M.10
Kwek, K.11
Teoh, O.H.12
-
113
-
-
84941166975
-
Breakthrough therapies: Cystic fibrosis (CF) potentiators and correctors
-
PID: 26097168
-
Solomon GM, Marshall SG, Ramsey BW, Rowe SM (2015) Breakthrough therapies: Cystic fibrosis (CF) potentiators and correctors. Pediatr Pulmonol 50(Suppl 40):S3–S13
-
(2015)
Pediatr Pulmonol
, vol.50
, pp. S3-S13
-
-
Solomon, G.M.1
Marshall, S.G.2
Ramsey, B.W.3
Rowe, S.M.4
-
114
-
-
84989246358
-
Therapeutic approaches to acquired cystic fibrosis transmembrane conductance regulator dysfunction in chronic bronchitis
-
PID: 27115953
-
Solomon GM, Raju SV, Dransfield MT, Rowe SM (2016) Therapeutic approaches to acquired cystic fibrosis transmembrane conductance regulator dysfunction in chronic bronchitis. Ann Am Thorac Soc 13(Suppl 2):S169–S176
-
(2016)
Ann Am Thorac Soc
, vol.13
, pp. S169-S176
-
-
Solomon, G.M.1
Raju, S.V.2
Dransfield, M.T.3
Rowe, S.M.4
-
115
-
-
85014775125
-
Comparison of lung clearance index and magnetic resonance imaging for assessment of lung disease in children with cystic fibrosis
-
Stahl M, Wielputz MO, Graeber SY, Joachim C, Sommerburg O, Kauczor HU, Puderbach M, Eichinger M, Mall MA (2016) Comparison of lung clearance index and magnetic resonance imaging for assessment of lung disease in children with cystic fibrosis. Am J Respir Crit Care Med doi:10.1164/rccm.201604-0893OC
-
(2016)
Am J Respir Crit Care Med doi:10.1164/rccm.201604-0893OC
-
-
Stahl, M.1
Wielputz, M.O.2
Graeber, S.Y.3
Joachim, C.4
Sommerburg, O.5
Kauczor, H.U.6
Puderbach, M.7
Eichinger, M.8
Mall, M.A.9
-
116
-
-
84979779103
-
Quantification of heterogeneity in lung disease with image-based pulmonary function testing
-
COI: 1:CAS:528:DC%2BC28Xht12ns7nK, PID: 27461961
-
Stahr CS, Samarage CR, Donnelley M, Farrow N, Morgan KS, Zosky G, Boucher RC, Siu KK, Mall MA, Parsons DW, Dubsky S, Fouras A (2016) Quantification of heterogeneity in lung disease with image-based pulmonary function testing. Sci Rep 6:29438
-
(2016)
Sci Rep
, vol.6
, pp. 29438
-
-
Stahr, C.S.1
Samarage, C.R.2
Donnelley, M.3
Farrow, N.4
Morgan, K.S.5
Zosky, G.6
Boucher, R.C.7
Siu, K.K.8
Mall, M.A.9
Parsons, D.W.10
Dubsky, S.11
Fouras, A.12
-
117
-
-
84979268325
-
Physiologic endpoints for clinical studies for cystic fibrosis
-
PID: 27316663
-
Stanojevic S, Ratjen F (2016) Physiologic endpoints for clinical studies for cystic fibrosis. J Cyst Fibros 15:416–423
-
(2016)
J Cyst Fibros
, vol.15
, pp. 416-423
-
-
Stanojevic, S.1
Ratjen, F.2
-
118
-
-
85014409703
-
-
Strug LJ, Gonska T, He G, Keenan K, Ip W, Boelle PY, Lin F, Panjwani N, Gong J, Li W, Soave D, Xiao B, Tullis E, Rabin H, Parkins MD, Price A, Zuberbuhler PC, Corvol H, Ratjen F, Sun L, Bear CE, Rommens JM (in press)
-
Strug LJ, Gonska T, He G, Keenan K, Ip W, Boelle PY, Lin F, Panjwani N, Gong J, Li W, Soave D, Xiao B, Tullis E, Rabin H, Parkins MD, Price A, Zuberbuhler PC, Corvol H, Ratjen F, Sun L, Bear CE, Rommens JM (2016) Cystic fibrosis gene modifier SLC26A9 modulates airway response to CFTR-directed therapeutics. Hum Mol Genet (in press)
-
(2016)
Cystic fibrosis gene modifier SLC26A9 modulates airway response to CFTR-directed therapeutics. Hum Mol Genet
-
-
-
119
-
-
84860350767
-
Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis
-
COI: 1:CAS:528:DC%2BC38XkvVKjtrk%3D, PID: 22466613
-
Sun L, Rommens JM, Corvol H, Li W, Li X, Chiang TA, Lin F, Dorfman R, Busson PF, Parekh RV, Zelenika D, Blackman SM, Corey M, Doshi VK, Henderson L, Naughton KM, O’Neal WK, Pace RG, Stonebraker JR, Wood SD, Wright FA, Zielenski J, Clement A, Drumm ML, Boelle PY, Cutting GR, Knowles MR, Durie PR, Strug LJ (2012) Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis. Nat Genet 44:562–569
-
(2012)
Nat Genet
, vol.44
, pp. 562-569
-
-
Sun, L.1
Rommens, J.M.2
Corvol, H.3
Li, W.4
Li, X.5
Chiang, T.A.6
Lin, F.7
Dorfman, R.8
Busson, P.F.9
Parekh, R.V.10
Zelenika, D.11
Blackman, S.M.12
Corey, M.13
Doshi, V.K.14
Henderson, L.15
Naughton, K.M.16
O’Neal, W.K.17
Pace, R.G.18
Stonebraker, J.R.19
Wood, S.D.20
Wright, F.A.21
Zielenski, J.22
Clement, A.23
Drumm, M.L.24
Boelle, P.Y.25
Cutting, G.R.26
Knowles, M.R.27
Durie, P.R.28
Strug, L.J.29
more..
-
120
-
-
84914143169
-
Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema
-
PID: 24828142
-
Trojanek JB, Cobos-Correa A, Diemer S, Kormann M, Schubert SC, Zhou-Suckow Z, Agrawal R, Duerr J, Wagner CJ, Schatterny J, Hirtz S, Sommerburg O, Hartl D, Schultz C, Mall MA (2014) Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema. Am J Respir Cell Mol Biol 51:709–720
-
(2014)
Am J Respir Cell Mol Biol
, vol.51
, pp. 709-720
-
-
Trojanek, J.B.1
Cobos-Correa, A.2
Diemer, S.3
Kormann, M.4
Schubert, S.C.5
Zhou-Suckow, Z.6
Agrawal, R.7
Duerr, J.8
Wagner, C.J.9
Schatterny, J.10
Hirtz, S.11
Sommerburg, O.12
Hartl, D.13
Schultz, C.14
Mall, M.A.15
-
121
-
-
84936792006
-
The role of serine proteases and antiproteases in the cystic fibrosis lung
-
PID: 26185359
-
Twigg MS, Brockbank S, Lowry P, FitzGerald SP, Taggart C, Weldon S (2015) The role of serine proteases and antiproteases in the cystic fibrosis lung. Mediators Inflamm 2015:293053. doi:10.1155/2015/293053
-
(2015)
Mediators Inflamm
, vol.2015
, pp. 293053
-
-
Twigg, M.S.1
Brockbank, S.2
Lowry, P.3
FitzGerald, S.P.4
Taggart, C.5
Weldon, S.6
-
122
-
-
0022657172
-
Mucociliary clearance in smokers
-
COI: 1:STN:280:DyaL287pt1Ontg%3D%3D, PID: 3699113
-
Vastag E, Matthys H, Zsamboki G, Kohler D, Daikeler G (1986) Mucociliary clearance in smokers. Eur J Respir Dis 68:107–113
-
(1986)
Eur J Respir Dis
, vol.68
, pp. 107-113
-
-
Vastag, E.1
Matthys, H.2
Zsamboki, G.3
Kohler, D.4
Daikeler, G.5
-
123
-
-
84873956600
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
-
COI: 1:CAS:528:DC%2BC3sXktVGhs7Y%3D, PID: 22878278
-
Vestbo J, Hurd SS, Agusti AG, Jones PW, Vogelmeier C, Anzueto A, Barnes PJ, Fabbri LM, Martinez FJ, Nishimura M, Stockley RA, Sin DD, Rodriguez-Roisin R (2013) Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 187:347–365
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 347-365
-
-
Vestbo, J.1
Hurd, S.S.2
Agusti, A.G.3
Jones, P.W.4
Vogelmeier, C.5
Anzueto, A.6
Barnes, P.J.7
Fabbri, L.M.8
Martinez, F.J.9
Nishimura, M.10
Stockley, R.A.11
Sin, D.D.12
Rodriguez-Roisin, R.13
-
124
-
-
85000790557
-
Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease
-
PID: 27456476
-
Wagner CJ, Schultz C, Mall MA (2016) Neutrophil elastase and matrix metalloproteinase 12 in cystic fibrosis lung disease. Mol Cell Pediatr 3:25
-
(2016)
Mol Cell Pediatr
, vol.3
, pp. 25
-
-
Wagner, C.J.1
Schultz, C.2
Mall, M.A.3
-
126
-
-
84942417500
-
Imaging modalities in cystic fibrosis: emerging role of MRI
-
PID: 26390331
-
Wielpütz MO, Mall MA (2015) Imaging modalities in cystic fibrosis: emerging role of MRI. Curr Opin Pulm Med 21:609–616
-
(2015)
Curr Opin Pulm Med
, vol.21
, pp. 609-616
-
-
Wielpütz, M.O.1
Mall, M.A.2
-
127
-
-
80355138065
-
In vivo monitoring of cystic fibrosis-like lung disease in mice by volumetric computed tomography
-
PID: 21478215
-
Wielpütz MO, Eichinger M, Zhou Z, Leotta K, Hirtz S, Bartling SH, Semmler W, Kauczor HU, Puderbach M, Mall MA (2011) In vivo monitoring of cystic fibrosis-like lung disease in mice by volumetric computed tomography. Eur Respir J 38:1060–1070
-
(2011)
Eur Respir J
, vol.38
, pp. 1060-1070
-
-
Wielpütz, M.O.1
Eichinger, M.2
Zhou, Z.3
Leotta, K.4
Hirtz, S.5
Bartling, S.H.6
Semmler, W.7
Kauczor, H.U.8
Puderbach, M.9
Mall, M.A.10
-
128
-
-
84898994097
-
Magnetic resonance imaging detects changes in structure and perfusion, and response to therapy in early cystic fibrosis lung disease
-
PID: 24564281
-
Wielputz MO, Puderbach M, Kopp-Schneider A, Stahl M, Fritzsching E, Sommerburg O, Ley S, Sumkauskaite M, Biederer J, Kauczor HU, Eichinger M, Mall MA (2014) Magnetic resonance imaging detects changes in structure and perfusion, and response to therapy in early cystic fibrosis lung disease. Am J Respir Crit Care Med 189:956–965
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 956-965
-
-
Wielputz, M.O.1
Puderbach, M.2
Kopp-Schneider, A.3
Stahl, M.4
Fritzsching, E.5
Sommerburg, O.6
Ley, S.7
Sumkauskaite, M.8
Biederer, J.9
Kauczor, H.U.10
Eichinger, M.11
Mall, M.A.12
-
129
-
-
0032545213
-
Interleukin-13: central mediator of allergic asthma
-
COI: 1:CAS:528:DyaK1cXotFGjsLk%3D, PID: 9856949
-
Wills-Karp M, Luyimbazi J, Xu X, Schofield B, Neben TY, Karp CL, Donaldson DD (1998) Interleukin-13: central mediator of allergic asthma. Science 282:2258–2261
-
(1998)
Science
, vol.282
, pp. 2258-2261
-
-
Wills-Karp, M.1
Luyimbazi, J.2
Xu, X.3
Schofield, B.4
Neben, T.Y.5
Karp, C.L.6
Donaldson, D.D.7
-
130
-
-
84923870560
-
Oxidation increases mucin polymer cross-links to stiffen airway mucus gels
-
COI: 1:CAS:528:DC%2BC2MXkt1Sgt70%3D, PID: 25717100
-
Yuan S, Hollinger M, Lachowicz-Scroggins ME, Kerr SC, Dunican EM, Daniel BM, Ghosh S, Erzurum SC, Willard B, Hazen SL, Huang X, Carrington SD, Oscarson S, Fahy JV (2015) Oxidation increases mucin polymer cross-links to stiffen airway mucus gels. Sci Transl Med 7:276ra27
-
(2015)
Sci Transl Med
, vol.7
, pp. 276ra27
-
-
Yuan, S.1
Hollinger, M.2
Lachowicz-Scroggins, M.E.3
Kerr, S.C.4
Dunican, E.M.5
Daniel, B.M.6
Ghosh, S.7
Erzurum, S.C.8
Willard, B.9
Hazen, S.L.10
Huang, X.11
Carrington, S.D.12
Oscarson, S.13
Fahy, J.V.14
-
132
-
-
0033761127
-
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema
-
COI: 1:CAS:528:DC%2BD3cXnvFyqtbg%3D, PID: 11067861
-
Zheng T, Zhu Z, Wang Z, Homer RJ, Ma B, Riese RJ Jr, Chapman HA Jr, Shapiro SD, Elias JA (2000) Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema. J Clin Invest 106:1081–1093
-
(2000)
J Clin Invest
, vol.106
, pp. 1081-1093
-
-
Zheng, T.1
Zhu, Z.2
Wang, Z.3
Homer, R.J.4
Ma, B.5
Riese, R.J.6
Chapman, H.A.7
Shapiro, S.D.8
Elias, J.A.9
-
133
-
-
57149104917
-
Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in bENaC-overexpressing mice
-
COI: 1:CAS:528:DC%2BD1MXmslyrsQ%3D%3D, PID: 18849497
-
Zhou Z, Treis D, Schubert SC, Harm M, Schatterny J, Hirtz S, Duerr J, Boucher RC, Mall MA (2008) Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in bENaC-overexpressing mice. Am J Respir Crit Care Med 178:1245–1256
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 1245-1256
-
-
Zhou, Z.1
Treis, D.2
Schubert, S.C.3
Harm, M.4
Schatterny, J.5
Hirtz, S.6
Duerr, J.7
Boucher, R.C.8
Mall, M.A.9
-
134
-
-
79958142002
-
The bENaC-overexpressing mouse as a model of cystic fibrosis lung disease
-
COI: 1:CAS:528:DC%2BC3MXpsVGisrY%3D, PID: 21658636
-
Zhou Z, Duerr J, Johannesson B, Schubert SC, Treis D, Harm M, Graeber SY, Dalpke A, Schultz C, Mall MA (2011) The bENaC-overexpressing mouse as a model of cystic fibrosis lung disease. J Cyst Fibros 10(Suppl 2):S172–S182
-
(2011)
J Cyst Fibros
, vol.10
, pp. S172-S182
-
-
Zhou, Z.1
Duerr, J.2
Johannesson, B.3
Schubert, S.C.4
Treis, D.5
Harm, M.6
Graeber, S.Y.7
Dalpke, A.8
Schultz, C.9
Mall, M.A.10
-
135
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
COI: 1:CAS:528:DyaK1MXhvFaku70%3D, PID: 10079098
-
Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA (1999) Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 103:779–788
-
(1999)
J Clin Invest
, vol.103
, pp. 779-788
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
Chen, Q.4
Geba, G.P.5
Wang, J.6
Zhang, Y.7
Elias, J.A.8
-
136
-
-
36849037262
-
The pathogenesis of fibrocystic disease of the pancreas; a study of 36 cases with special reference to the pulmonary lesions
-
COI: 1:STN:280:DyaH1M%2FkvVSnsw%3D%3D, PID: 18146464
-
Zuelzer WW, Newton WA (1949) The pathogenesis of fibrocystic disease of the pancreas; a study of 36 cases with special reference to the pulmonary lesions. Pediatrics 4:53–69
-
(1949)
Pediatrics
, vol.4
, pp. 53-69
-
-
Zuelzer, W.W.1
Newton, W.A.2
|