Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype

Journal of Experimental Medicine

Volumn 209, Issue 7, 2012, Pages 1263-1272

  Gustafsson, Jenny K ^a   Ermund, Anna ^a   Ambort, Daniel ^a   Johansson, Malin E V ^a   Nilsson, Harriet E ^b   Thorell, Kaisa ^a   Hebert, Hans ^b   Sjövall, Henrik ^a   Hansson, Gunnar C ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; MUCIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; ILEUM MUCOSA; INTESTINE SECRETION; MEMBRANE TRANSPORT; MOUSE; MUCUS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; BICARBONATES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIUM; FEMALE; ILEUM; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; MUCINS; MUCUS; PHENOTYPE;

EID: 84864313785     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20120562     Document Type: Article

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