-
1
-
-
84883495690
-
Respiratory health and disease in Europe: The new European LungWhite Book
-
G. J. Gibson, R. Loddenkemper, B. Lundback, and Y. Sibille, "Respiratory health and disease in Europe: the new European LungWhite Book" European Respiratory Journal, vol. 42, no. 3, pp. 559-563, 2013.
-
(2013)
European Respiratory Journal
, vol.42
, Issue.3
, pp. 559-563
-
-
Gibson, G.J.1
Loddenkemper, R.2
Lundback, B.3
Sibille, Y.4
-
2
-
-
0026699623
-
Cyclic AMP-dependent protein kinase activation of cystic fibrosis transmembrane conductance regulator chloride channels in planar lipid bilayers
-
B. C. Tilly, M. C. Winter, L. S. Ostedgaard, C. O'Riordan, A. E. Smith, and M. J. Welsh, "Cyclic AMP-dependent protein kinase activation of cystic fibrosis transmembrane conductance regulator chloride channels in planar lipid bilayers" The Journal of Biological Chemistry, vol. 267, no. 14, pp. 9470-9473, 1992.
-
(1992)
The Journal of Biological Chemistry
, vol.267
, Issue.14
, pp. 9470-9473
-
-
Tilly, B.C.1
Winter, M.C.2
Ostedgaard, L.S.3
O'riordan, C.4
Smith, A.E.5
Welsh, M.J.6
-
3
-
-
33846284918
-
Pseudomonas aeruginosa chronic colonization in cystic fibrosis patients
-
T. S. Murray, M. Egan, and B. I. Kazmierczak, "Pseudomonas aeruginosa chronic colonization in cystic fibrosis patients" Current Opinion in Pediatrics, vol. 19, no. 1, pp. 83-88, 2007.
-
(2007)
Current Opinion in Pediatrics
, vol.19
, Issue.1
, pp. 83-88
-
-
Murray, T.S.1
Egan, M.2
Kazmierczak, B.I.3
-
4
-
-
80051572617
-
Infection, inflammation, and lung function decline in infants with cystic fibrosis
-
N. Pillarisetti, E. Williamson, B. Linnane et al., "Infection, inflammation, and lung function decline in infants with cystic fibrosis" American Journal of Respiratory and Critical Care Medicine, vol. 184, no. 1, pp. 75-81, 2011.
-
(2011)
American Journal of Respiratory and Critical Care Medicine
, vol.184
, Issue.1
, pp. 75-81
-
-
Pillarisetti, N.1
Williamson, E.2
Linnane, B.3
-
5
-
-
23744490412
-
Neutrophil cell death, activation and bacterial infection in cystic fibrosis
-
A. P. Watt, J. Courtney, J. Moore, M. Ennis, and J. S. Elborn, "Neutrophil cell death, activation and bacterial infection in cystic fibrosis" Thorax, vol. 60, no. 8, pp. 659-664, 2005.
-
(2005)
Thorax
, vol.60
, Issue.8
, pp. 659-664
-
-
Watt, A.P.1
Courtney, J.2
Moore, J.3
Ennis, M.4
Elborn, J.S.5
-
6
-
-
0034997191
-
Proinflammatory cytokine responses to P aeruginosa infection in human airway epithelial cell lines
-
D. Kube, U. Sontich, D. Fletcher, and P. B. Davis, "Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines" The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 280, no. 3, pp. L493-L502, 2001.
-
(2001)
The American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.280
, Issue.3
, pp. L493-L502
-
-
Kube, D.1
Sontich, U.2
Fletcher, D.3
Davis, P.B.4
-
7
-
-
0027477775
-
Sputum tumour necrosis factor-And leukotriene concentrations in cystic fibrosis
-
P. Greally, M. J. Hussein, A. J. Cook, A. P. Sampson, P. J. Piper, and J. F. Price, "Sputum tumour necrosis factor-And leukotriene concentrations in cystic fibrosis" Archives ofDisease in Childhood, vol. 68, no. 3, pp. 389-392, 1993.
-
(1993)
Archives OfDisease in Childhood
, vol.68
, Issue.3
, pp. 389-392
-
-
Greally, P.1
Hussein, M.J.2
Cook, A.J.3
Sampson, A.P.4
Piper, P.J.5
Price, J.F.6
-
8
-
-
58349104978
-
Neutrophils in cystic fibrosis
-
D. G. Downey, S.C. Bell, and J. S. Elborn, "Neutrophils in cystic fibrosis" Thorax, vol. 64, no. 1, pp. 81-88, 2009.
-
(2009)
Thorax
, vol.64
, Issue.1
, pp. 81-88
-
-
Downey, D.G.1
Bell, S.C.2
Elborn, J.S.3
-
9
-
-
39649120097
-
Targeting neutrophil elastase in cystic fibrosis
-
E. Kelly, C. M. Greene, and N. G. McElvaney, "Targeting neutrophil elastase in cystic fibrosis"ExpertOpinion onTherapeutic Targets, vol. 12, no. 2, pp. 145-157, 2008.
-
(2008)
ExpertOpinion OnTherapeutic Targets
, vol.12
, Issue.2
, pp. 145-157
-
-
Kelly, E.1
Greene, C.M.2
McElvaney, N.G.3
-
10
-
-
0042360446
-
Neutrophil recruitment and airway epithelial cell involvement in chronic cystic fibrosis lung disease
-
M. Conese, E. Copreni, S. di Gioia, P. de Rinaldis, and R. Fumarulo, "Neutrophil recruitment and airway epithelial cell involvement in chronic cystic fibrosis lung disease" Journal of Cystic Fibrosis, vol. 2, no. 3, pp. 129-135, 2003.
-
(2003)
Journal of Cystic Fibrosis
, vol.2
, Issue.3
, pp. 129-135
-
-
Conese, M.1
Copreni, E.2
Di Gioia, S.3
De Rinaldis, P.4
Fumarulo, R.5
-
11
-
-
79952535973
-
Thecystic fibrosis neutrophil: A specialized yet potentially defective cell
-
E. Hayes, K. Pohl, N.G. McElvaney, and E. P. Reeves, "Thecystic fibrosis neutrophil: a specialized yet potentially defective cell" Archivum Immunologiae et Therapiae Experimentalis, vol. 59, no. 2, pp. 97-112, 2011.
-
(2011)
Archivum Immunologiae et Therapiae Experimentalis
, vol.59
, Issue.2
, pp. 97-112
-
-
Hayes, E.1
Pohl, K.2
McElvaney, N.G.3
Reeves, E.P.4
-
12
-
-
84859620802
-
Cystic fibrosis: A mucosal immunodeficiency syndrome
-
T. S. Cohen and A. Prince, "Cystic fibrosis: a mucosal immunodeficiency syndrome" Nature Medicine, vol. 18, no. 4, pp. 509-519, 2012.
-
(2012)
Nature Medicine
, vol.18
, Issue.4
, pp. 509-519
-
-
Cohen, T.S.1
Prince, A.2
-
13
-
-
84890553047
-
The role of neutrophils in cystic fibrosis
-
A. M. Gifford and J. D. Chalmers, "The role of neutrophils in cystic fibrosis" Current Opinion in Hematology, vol. 21, no. 1, pp. 16-22, 2014.
-
(2014)
Current Opinion in Hematology
, vol.21
, Issue.1
, pp. 16-22
-
-
Gifford, A.M.1
Chalmers, J.D.2
-
14
-
-
0032722467
-
Granulocyte apoptosis and its role in the resolution and control of lung inflammation
-
C. Haslett, "Granulocyte apoptosis and its role in the resolution and control of lung inflammation" The American Journal of Respiratory and Critical Care Medicine, vol. 160, no. 5, pp. S5-S11, 1999.
-
(1999)
The American Journal of Respiratory and Critical Care Medicine
, vol.160
, Issue.5
, pp. S5-S11
-
-
Haslett, C.1
-
15
-
-
78650096176
-
Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases
-
B. Korkmaz, M. S. Horwitz, D. E. Jenne, and F. Gauthier, "Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases" Pharmacological Reviews, vol. 62, no. 4, pp. 726-759, 2010.
-
(2010)
Pharmacological Reviews
, vol.62
, Issue.4
, pp. 726-759
-
-
Korkmaz, B.1
Horwitz, M.S.2
Jenne, D.E.3
Gauthier, F.4
-
16
-
-
57649155302
-
Proteases: Multifunctional enzymes in life and disease
-
C. Lopez-Ot and J. S. Bond, "Proteases: multifunctional enzymes in life and disease" Journal of Biological Chemistry, vol. 283, no. 45, pp. 30433-30437, 2008.
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.45
, pp. 30433-30437
-
-
Lopez-Ot, C.1
Bond, J.S.2
-
17
-
-
38849143983
-
Neutrophil elastase, proteinase 3 and cathepsin G: Physicochemical properties, activity and physiopathological functions
-
B. Korkmaz, T. Moreau, and F. Gauthier, "Neutrophil elastase, proteinase 3 and cathepsin G: physicochemical properties, activity and physiopathological functions" Biochimie, vol. 90, no. 2, pp. 227-242, 2008.
-
(2008)
Biochimie
, vol.90
, Issue.2
, pp. 227-242
-
-
Korkmaz, B.1
Moreau, T.2
Gauthier, F.3
-
18
-
-
0033587689
-
Dipeptidyl peptidase i is required for the processing and activation of granzymesAand B in vivo
-
C. T. N. Pham and T. J. Ley, "Dipeptidyl peptidase I is required for the processing and activation of granzymesAand B in vivo" Proceedings of the National Academy of Sciences of the United States of America, vol. 96, no. 15, pp. 8627-8632, 1999.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.15
, pp. 8627-8632
-
-
Pham, C.T.N.1
Ley, T.J.2
-
19
-
-
0035947568
-
Dipeptidyl peptidase i is essential for activation of mast cell chymases, but not tryptases, in mice
-
P. J. Wolters, C. T. N. Pham, D. J. Muilenburg, T. J. Ley, and G. H. Caughey, "Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice" The Journal of Biological Chemistry, vol. 276, no. 21, pp. 18551-18556, 2001.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, Issue.21
, pp. 18551-18556
-
-
Wolters, P.J.1
Pham, C.T.N.2
Muilenburg, D.J.3
Ley, T.J.4
Caughey, G.H.5
-
20
-
-
0036168150
-
Dipeptidyl peptidase i activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis
-
A. M. Adkison, S. Z. Raptis, D. G. Kelley, and C. T. N. Pham, "Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis"The Journal of Clinical Investigation, vol. 109, no. 3, pp. 363-371, 2002.
-
(2002)
The Journal of Clinical Investigation
, vol.109
, Issue.3
, pp. 363-371
-
-
Adkison, A.M.1
Raptis, S.Z.2
Kelley, D.G.3
Pham, C.T.N.4
-
21
-
-
0036324435
-
Functional dissociation between proforms and mature forms of proteinase 3, azurocidin, and granzyme B in regulation of granulopoiesis
-
S. Skld, L. Zeberg, U. Gullberg, and T. Olofsson, "Functional dissociation between proforms and mature forms of proteinase 3, azurocidin, and granzyme B in regulation of granulopoiesis" Experimental Hematology, vol. 30, no. 7, pp. 689-696, 2002.
-
(2002)
Experimental Hematology
, vol.30
, Issue.7
, pp. 689-696
-
-
Skld, S.1
Zeberg, L.2
Gullberg, U.3
Olofsson, T.4
-
22
-
-
0029073056
-
Carboxyl-terminal prodomain-deleted human leukocyte elastase and cathepsin G are efficiently targeted to granules and enzymatically activated in the rat basophilic/mast cell line RBL
-
U. Gullberg, A. Lindmark, G. Lindgren, A.-M. Persson, E. Nilsson, and I. Olsson, "Carboxyl-terminal prodomain-deleted human leukocyte elastase and cathepsin G are efficiently targeted to granules and enzymatically activated in the rat basophilic/mast cell line RBL" The Journal of Biological Chemistry, vol. 270, no. 21, pp. 12912-12918, 1995.
-
(1995)
The Journal of Biological Chemistry
, vol.270
, Issue.21
, pp. 12912-12918
-
-
Gullberg, U.1
Lindmark, A.2
Lindgren, G.3
Persson, A.-M.4
Nilsson, E.5
Olsson, I.6
-
23
-
-
0033113290
-
Proteinase 3, a potent secretagogue in airways, is present in cystic fibrosis sputum
-
V. Witko-Sarsat, L. Halbwachs-Mecarelli, A. Schuster et al., "Proteinase 3, a potent secretagogue in airways, is present in cystic fibrosis sputum" American Journal of Respiratory Cell and Molecular Biology, vol. 20, no. 4, pp. 729-736, 1999.
-
(1999)
American Journal of Respiratory Cell and Molecular Biology
, vol.20
, Issue.4
, pp. 729-736
-
-
Witko-Sarsat, V.1
Halbwachs-Mecarelli, L.2
Schuster, A.3
-
24
-
-
0028816887
-
Presence, activities, and molecular forms of cathepsin G, elastase, 1-Antitrypsin, and 1-Antichymotrypsin in bronchiectasis
-
R. Sepper, Y. T. Konttinen, T. Ingman, and T. Sorsa, "Presence, activities, and molecular forms of cathepsin G, elastase, 1-Antitrypsin, and 1-Antichymotrypsin in bronchiectasis" Journal of Clinical Immunology, vol. 15, no. 1, pp. 27-34, 1995.
-
(1995)
Journal of Clinical Immunology
, vol.15
, Issue.1
, pp. 27-34
-
-
Sepper, R.1
Konttinen, Y.T.2
Ingman, T.3
Sorsa, T.4
-
25
-
-
0026754577
-
Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter
-
M. Zimmer, R. L. Medcalf, T. M. Fink, C. Mattmann, P. Lichter, and D. E. Jenne, "Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter" Proceedings of the National Academy of Sciences of the United States of America, vol. 89, no. 17, pp. 8215-8219, 1992.
-
(1992)
Proceedings of the National Academy of Sciences of the United States of America
, vol.89
, Issue.17
, pp. 8215-8219
-
-
Zimmer, M.1
Medcalf, R.L.2
Fink, T.M.3
Mattmann, C.4
Lichter, P.5
Jenne, D.E.6
-
26
-
-
0028015883
-
Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation
-
M. W. Konstan, K. A. Hilliard, T. M. Norvell, and M. Berger, "Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation"AmericanJournal of Respiratory andCritical Care Medicine, vol. 150, no. 2, pp. 448-454, 1994.
-
(1994)
American Journal of Respiratory AndCritical Care Medicine
, vol.150
, Issue.2
, pp. 448-454
-
-
Konstan, M.W.1
Hilliard, K.A.2
Norvell, T.M.3
Berger, M.4
-
27
-
-
0029126156
-
Increased degranulation of eosinophil and neutrophil granulocytes in cystic fibrosis
-
D. Y. Koller, R. Urbanek, and M. Gtz, "Increased degranulation of eosinophil and neutrophil granulocytes in cystic fibrosis"The American Journal of Respiratory and Critical CareMedicine, vol. 152, no. 2, pp. 629-633, 1995.
-
(1995)
The American Journal of Respiratory and Critical Care Medicine
, vol.152
, Issue.2
, pp. 629-633
-
-
Koller, D.Y.1
Urbanek, R.2
Gtz, M.3
-
28
-
-
0033962098
-
Increased elastase release by CF neutrophils is mediated by tumor necrosis factor-Alpha and interleukin-8
-
C. Taggart, R. J. Coakley, P. Greally, G. Canny, S. J. O'Neill, and N. G. McElvaney, "Increased elastase release by CF neutrophils is mediated by tumor necrosis factor-Alpha and interleukin-8" The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 278, no. 1, pp. L33-L41, 2000.
-
(2000)
The American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.278
, Issue.1
, pp. L33-L41
-
-
Taggart, C.1
Coakley, R.J.2
Greally, P.3
Canny, G.4
O'neill, S.J.5
McElvaney, N.G.6
-
29
-
-
84905992903
-
Aneutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy
-
K. Pohl, E. Hayes, J. Keenanet al., "Aneutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy" Blood, vol. 124, no. 7, pp. 999-1009, 2014.
-
(2014)
Blood
, vol.124
, Issue.7
, pp. 999-1009
-
-
Pohl, K.1
Hayes, E.2
Keenan, J.3
-
30
-
-
43049135102
-
Proteases and cystic fibrosis
-
J. A. Voynow, B. M. Fischer, and S. Zheng, "Proteases and cystic fibrosis"The International Journal of Biochemistry & Cell Biology, vol. 40, no. 6-7, pp. 1238-1245, 2008.
-
(2008)
The International Journal of Biochemistry & Cell Biology
, vol.40
, Issue.6-7
, pp. 1238-1245
-
-
Voynow, J.A.1
Fischer, B.M.2
Zheng, S.3
-
31
-
-
84879285251
-
CFTR, mucins, and mucus obstruction in cystic fibrosis
-
Article ID a009589
-
S. M. Kreda, C. W. Davis, and M. C. Rose, "CFTR, mucins, and mucus obstruction in cystic fibrosis" Cold Spring Harbor Perspectives in Medicine, vol. 2, no. 9, Article ID a009589, 2012.
-
(2012)
Cold Spring Harbor Perspectives in Medicine
, vol.2
, Issue.9
-
-
Kreda, S.M.1
Davis, C.W.2
Rose, M.C.3
-
32
-
-
60249095813
-
Mucins, mucus, and sputum
-
J. A. Voynow and B. K. Rubin, "Mucins, mucus, and sputum" Chest, vol. 135, no. 2, pp. 505-512, 2009.
-
(2009)
Chest
, vol.135
, Issue.2
, pp. 505-512
-
-
Voynow, J.A.1
Rubin, B.K.2
-
33
-
-
24744464353
-
Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-converting enzyme
-
M. X. G. Shao and J. A. Nadel, "Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-converting enzyme" The Journal of Immunology, vol. 175, no. 6, pp. 4009-4016, 2005.
-
(2005)
The Journal of Immunology
, vol.175
, Issue.6
, pp. 4009-4016
-
-
Shao, M.X.G.1
Nadel, J.A.2
-
34
-
-
33645816115
-
Neutrophil elastase causesMUC5ACmucin synthesis via EGF receptor, ERK and NF-B pathways in A549 cells
-
J.-S. Song, K.-S. Cho, H.-K. Yoon, H.-S. Moon, and S.-H. Park, "Neutrophil elastase causesMUC5ACmucin synthesis via EGF receptor, ERK and NF-B pathways in A549 cells" Korean Journal of Internal Medicine, vol. 20, no. 4, pp. 275-283, 2005.
-
(2005)
Korean Journal of Internal Medicine
, vol.20
, Issue.4
, pp. 275-283
-
-
Song, J.-S.1
Cho, K.-S.2
Yoon, H.-K.3
Moon, H.-S.4
Park, S.-H.5
-
35
-
-
0036009464
-
Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species
-
B. M. Fischer and J. A. Voynow, "Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species" The American Journal of Respiratory Cell and Molecular Biology, vol. 26, no. 4, pp. 447-452, 2002.
-
(2002)
The American Journal of Respiratory Cell and Molecular Biology
, vol.26
, Issue.4
, pp. 447-452
-
-
Fischer, B.M.1
Voynow, J.A.2
-
36
-
-
0037377489
-
Neutrophil elastase increases MUC4 expression in normal human bronchial epithelial cells
-
B. M. Fischer, J. G. Cuellar, M. L. Diehl et al., "Neutrophil elastase increases MUC4 expression in normal human bronchial epithelial cells" American Journal of Physiology: Lung Cellular and Molecular Physiology, vol. 284, no. 4, pp. L671-L679, 2003.
-
(2003)
American Journal of Physiology: Lung Cellular and Molecular Physiology
, vol.284
, Issue.4
, pp. L671-L679
-
-
Fischer, B.M.1
Cuellar, J.G.2
Diehl, M.L.3
-
37
-
-
22444438518
-
Neutrophil elastase stimulates MUC1 gene expression through increased Sp1 binding to the MUC1 promoter
-
I. Kuwahara, E. P. Lillehoj, A. Hisatsune et al., "Neutrophil elastase stimulates MUC1 gene expression through increased Sp1 binding to the MUC1 promoter" American Journal of Physiology: Lung Cellular andMolecular Physiology, vol. 289, no. 2, pp. L355-L362, 2005.
-
(2005)
American Journal of Physiology: Lung Cellular AndMolecular Physiology
, vol.289
, Issue.2
, pp. L355-L362
-
-
Kuwahara, I.1
Lillehoj, E.P.2
Hisatsune, A.3
-
38
-
-
36749010192
-
The signaling pathway involved in neutrophil elastase-stimulated MUC1 transcription
-
I. Kuwahara, E. P. Lillehoj, T. Koga, Y. Isohama, T. Miyata, and K. C. Kim, "The signaling pathway involved in neutrophil elastase-stimulated MUC1 transcription" American Journal of Respiratory Cell and Molecular Biology, vol. 37, no. 6, pp. 691-698, 2007.
-
(2007)
American Journal of Respiratory Cell and Molecular Biology
, vol.37
, Issue.6
, pp. 691-698
-
-
Kuwahara, I.1
Lillehoj, E.P.2
Koga, T.3
Isohama, Y.4
Miyata, T.5
Kim, K.C.6
-
39
-
-
24044456312
-
Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinaseC-mediatedmechanism
-
J.-A. Park, F. He, L. D. Martin, Y. Li, B. N. Chorley, and K. B. Adler, "Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinaseC-mediatedmechanism" The American Journal of Pathology, vol. 167, no. 3, pp. 651-661, 2005.
-
(2005)
The American Journal of Pathology
, vol.167
, Issue.3
, pp. 651-661
-
-
Park, J.-A.1
He, F.2
Martin, L.D.3
Li, Y.4
Chorley, B.N.5
Adler, K.B.6
-
40
-
-
84899791723
-
Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosislike lung disease
-
S. Gehrig, J. Duerr, M. Weitnauer et al., "Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosislike lung disease" American Journal of Respiratory and Critical Care Medicine, vol. 189, no. 9, pp. 1082-1092, 2014.
-
(2014)
American Journal of Respiratory and Critical Care Medicine
, vol.189
, Issue.9
, pp. 1082-1092
-
-
Gehrig, S.1
Duerr, J.2
Weitnauer, M.3
-
41
-
-
0025982378
-
Effects of human neutrophil elastase and Pseudomonas aeruginosa proteinases on human respiratory epithelium
-
R. Amitani, R. Wilson, A. Rutman et al., "Effects of human neutrophil elastase and Pseudomonas aeruginosa proteinases on human respiratory epithelium"American Journal of Respiratory Cell and Molecular Biology, vol. 4, no. 1, pp. 26-32, 1991.
-
(1991)
Journal of Respiratory Cell and Molecular Biology A.
, vol.4
, Issue.1
, pp. 26-32
-
-
Amitani, R.1
Wilson, R.2
Rutman, A.3
-
42
-
-
45949094270
-
Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: Lessons from mouse models
-
M. A. Mall, "Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models" Journal of AerosolMedicine and Pulmonary Drug Delivery, vol. 21, no. 1, pp. 13-24, 2008.
-
(2008)
Journal of AerosolMedicine and Pulmonary Drug Delivery
, vol.21
, Issue.1
, pp. 13-24
-
-
Mall, M.A.1
-
43
-
-
84920273225
-
Linking increased airway hydration, ciliary beating, and mucociliary clearance through ENaC inhibition
-
A. B. Astrand, M. Hemmerling, J. Root et al., "Linking increased airway hydration, ciliary beating, and mucociliary clearance through ENaC inhibition" The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 308, no. 1, pp. L22-L32, 2015.
-
(2015)
The American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.308
, Issue.1
, pp. L22-L32
-
-
Astrand, A.B.1
Hemmerling, M.2
Root, J.3
-
44
-
-
0027998135
-
The role of neutrophil elastase in chronic inflammation
-
G. Dring, "The role of neutrophil elastase in chronic inflammation" American Journal of Respiratory and Critical Care Medicine, vol. 150, no. 6, pp. S114-S117, 1994.
-
(1994)
American Journal of Respiratory and Critical Care Medicine
, vol.150
, Issue.6
, pp. S114-S117
-
-
Dring, G.1
-
45
-
-
0026681802
-
Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line
-
H. Nakamura, K. Yoshimura, N. G. McElvaney, and R. G. Crystal, "Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line" Journal of Clinical Investigation, vol. 89, no. 5, pp. 1478-1484, 1992.
-
(1992)
Journal of Clinical Investigation
, vol.89
, Issue.5
, pp. 1478-1484
-
-
Nakamura, H.1
Yoshimura, K.2
McElvaney, N.G.3
Crystal, R.G.4
-
46
-
-
0038018539
-
Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4
-
J. M. Devaney, C.M. Greene, C. C. Taggart, T. P. Carroll, S. J. O'Neill, andN. G. McElvaney, "Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4" FEBS Letters, vol. 544, no. 1-3, pp. 129-132, 2003.
-
(2003)
FEBS Letters
, vol.544
, Issue.1-3
, pp. 129-132
-
-
Devaney, J.M.1
Greene, C.M.2
Taggart, C.C.3
Carroll, T.P.4
O'neill, N.G.5
McElvaney, S.J.6
-
47
-
-
0034282683
-
Oxidation of either methionine 351 or methionine 358 in alpha1-Antitrypsin causes loss of anti-neutrophil elastase activity
-
C. Taggart, D. Cervantes-Laurean, G. Kim et al., "Oxidation of either methionine 351 or methionine 358 in alpha1-Antitrypsin causes loss of anti-neutrophil elastase activity" The Journal of Biological Chemistry, vol. 275, no. 35, pp. 27258-27265, 2000.
-
(2000)
The Journal of Biological Chemistry
, vol.275
, Issue.35
, pp. 27258-27265
-
-
Taggart, C.1
Cervantes-Laurean, D.2
Kim, G.3
-
48
-
-
0035929634
-
Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/ IRAK/TRAF-6 in human bronchial epithelium
-
D. E. Walsh, C. M. Greene, T. P. Carroll et al., "Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/ IRAK/TRAF-6 in human bronchial epithelium" Journal of Biological Chemistry, vol. 276, no. 38, pp. 35494-35499, 2001.
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.38
, pp. 35494-35499
-
-
Walsh, D.E.1
Greene, C.M.2
Carroll, T.P.3
-
49
-
-
0036720456
-
Role of Toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils
-
E. A. Kurt-Jones, L. Mandell, C. Whitney et al., "Role of Toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils" Blood, vol. 100, no. 5, pp. 1860-1868, 2002.
-
(2002)
Blood
, vol.100
, Issue.5
, pp. 1860-1868
-
-
Kurt-Jones, E.A.1
Mandell, L.2
Whitney, C.3
-
50
-
-
0031041367
-
Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury
-
G. Ferry, M. Lonchampt, L. Pennel, G. de Nanteuil, E. Canet, and G. C. Tucker, "Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury" FEBS Letters, vol. 402, no. 2-3, pp. 111-115, 1997.
-
(1997)
FEBS Letters
, vol.402
, Issue.2-3
, pp. 111-115
-
-
Ferry, G.1
Lonchampt, M.2
Pennel, L.3
De Nanteuil, G.4
Canet, E.5
Tucker, G.C.6
-
51
-
-
77951951482
-
Human neutrophil elastase-mediated cleavage sites of MMP-9 and TIMP-1: Implications to cystic fibrosis proteolytic dysfunction
-
P. L. Jackson, X. Xu, L. Wilson et al., "Human neutrophil elastase-mediated cleavage sites of MMP-9 and TIMP-1: implications to cystic fibrosis proteolytic dysfunction" Molecular Medicine, vol. 16, no. 5-6, pp. 159-166, 2010.
-
(2010)
Molecular Medicine
, vol.16
, Issue.5-6
, pp. 159-166
-
-
Jackson, P.L.1
Xu, X.2
Wilson, L.3
-
52
-
-
0346734183
-
Neutrophil serine proteinases cleave bacterial flagellin, abrogating its host response-inducing activity
-
Y. S. Lopez-Boado, M. Espinola, S. Bahr, and A. Belaaouaj, "Neutrophil serine proteinases cleave bacterial flagellin, abrogating its host response-inducing activity" The Journal of Immunology, vol. 172, no. 1, pp. 509-515, 2004.
-
(2004)
The Journal of Immunology
, vol.172
, Issue.1
, pp. 509-515
-
-
Lopez-Boado, Y.S.1
Espinola, M.2
Bahr, S.3
Belaaouaj, A.4
-
53
-
-
33845481599
-
Neutrophil elastase, an innate immunity effector molecule, represses flagellin transcription in Pseudomonas aeruginosa
-
A. Sonawane, J. Jyot, R. During, and R. Ramphal, "Neutrophil elastase, an innate immunity effector molecule, represses flagellin transcription in Pseudomonas aeruginosa" Infection and Immunity, vol. 74, no. 12, pp. 6682-6689, 2006.
-
(2006)
Infection and Immunity
, vol.74
, Issue.12
, pp. 6682-6689
-
-
Sonawane, A.1
Jyot, J.2
During, R.3
Ramphal, R.4
-
55
-
-
0025374923
-
Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch
-
M. F. Tosi, H. Zakem, and M. Berger, "Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch" Journal of Clinical Investigation, vol. 86, no. 1, pp. 300-308, 1990.
-
(1990)
Journal of Clinical Investigation
, vol.86
, Issue.1
, pp. 300-308
-
-
Tosi, M.F.1
Zakem, H.2
Berger, M.3
-
56
-
-
84894239912
-
Mechanism of neutrophil dysfunction: Neutrophil serine proteases cleave and inactivate the C5a receptor
-
C.W. van den Berg, D. V. Tambourgi, H. W. Clark, S. J. Hoong, O. B. Spiller, and E. P. McGreal, "Mechanism of neutrophil dysfunction: neutrophil serine proteases cleave and inactivate the C5a receptor"The Journal of Immunology, vol. 192, no. 4, pp. 1787-1795, 2014.
-
(2014)
The Journal of Immunology
, vol.192
, Issue.4
, pp. 1787-1795
-
-
Van Den Berg, C.W.1
Tambourgi, D.V.2
Clark, H.W.3
Hoong, S.J.4
Spiller, O.B.5
McGreal, E.P.6
-
57
-
-
4644263748
-
Loss of microbial activity and increased formation of biofilm due to decreased lactoferrin activity in patients with cystic fibrosis
-
M. P. Rogan, C. C. Taggart, C. M. Greene, P. G. Murphy, S. J. O'Neill, and N. G. McElvaney, "Loss of microbial activity and increased formation of biofilm due to decreased lactoferrin activity in patients with cystic fibrosis" Journal of Infectious Diseases, vol. 190, no. 7, pp. 1245-1253, 2004.
-
(2004)
Journal of Infectious Diseases
, vol.190
, Issue.7
, pp. 1245-1253
-
-
Rogan, M.P.1
Taggart, C.C.2
Greene, C.M.3
Murphy, P.G.4
O'neill, S.J.5
McElvaney, N.G.6
-
58
-
-
0037860827
-
Neutrophil elastase up-regulates human-Defensin-2 expression in human bronchial epithelial cells
-
S. Griffin, C. C. Taggart, C. M. Greene, S. O'Neill, and N. G. McElvaney, "Neutrophil elastase up-regulates human-defensin-2 expression in human bronchial epithelial cells" FEBS Letters, vol. 546, no. 2-3, pp. 233-236, 2003.
-
(2003)
FEBS Letters
, vol.546
, Issue.2-3
, pp. 233-236
-
-
Griffin, S.1
Taggart, C.C.2
Greene, C.M.3
O'neill, S.4
McElvaney, N.G.5
-
59
-
-
0036195343
-
Elastasemediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis
-
R. W. Vandivier, V. A. Fadok, P. R. Hoffmann et al., "Elastasemediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis" The Journal of Clinical Investigation, vol. 109, no. 5, pp. 661-670, 2002.
-
(2002)
The Journal of Clinical Investigation
, vol.109
, Issue.5
, pp. 661-670
-
-
Vandivier, R.W.1
Fadok, V.A.2
Hoffmann, P.R.3
-
60
-
-
0029067051
-
Cleavage of lymphocyte surface antigens CD2, CD4, and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis
-
G. Doring, F. Frank, C. Boudier, S. Herbert, B. Fleischer, and G. Bellon, "Cleavage of lymphocyte surface antigens CD2, CD4, and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis" Journal of Immunology, vol. 154, no. 9, pp. 4842-4850, 1995.
-
(1995)
Journal of Immunology
, vol.154
, Issue.9
, pp. 4842-4850
-
-
Doring, G.1
Frank, F.2
Boudier, C.3
Herbert, S.4
Fleischer, B.5
Bellon, G.6
-
61
-
-
0032900462
-
Proteolysis of monocyte CD14 by human leukocyte elastase inhibits lipopolysaccharide-mediated cell activation
-
K. Le-Barillec, M. Si-Tahar, V. Balloy, and M. Chignard, "Proteolysis of monocyte CD14 by human leukocyte elastase inhibits lipopolysaccharide-mediated cell activation" Journal of Clinical Investigation, vol. 103, no. 7, pp. 1039-1046, 1999.
-
(1999)
Journal of Clinical Investigation
, vol.103
, Issue.7
, pp. 1039-1046
-
-
Le-Barillec, K.1
Si-Tahar, M.2
Balloy, V.3
Chignard, M.4
-
62
-
-
33846432787
-
Novel cell death program leads to neutrophil extracellular traps
-
T. A. Fuchs, U. Abed, C. Goosmann et al., "Novel cell death program leads to neutrophil extracellular traps" The Journal of Cell Biology, vol. 176, no. 2, pp. 231-241, 2007.
-
(2007)
The Journal of Cell Biology
, vol.176
, Issue.2
, pp. 231-241
-
-
Fuchs, T.A.1
Abed, U.2
Goosmann, C.3
-
63
-
-
78049496216
-
Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps
-
V. Papayannopoulos, K. D. Metzler, A. Hakkim, and A. Zychlinsky, "Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps" Journal of Cell Biology, vol. 191, no. 3, pp. 677-691, 2010.
-
(2010)
Journal of Cell Biology
, vol.191
, Issue.3
, pp. 677-691
-
-
Papayannopoulos, V.1
Metzler, K.D.2
Hakkim, A.3
Zychlinsky, A.4
-
64
-
-
84908201445
-
A myeloperoxidase-containing complex regulates neutrophil elastase release and actin dynamics during NETosis
-
K.D. Metzler, C. Goosmann, A. Lubojemska, A. Zychlinsky, and V. Papayannopoulos, "A myeloperoxidase-containing complex regulates neutrophil elastase release and actin dynamics during NETosis" Cell Reports, vol. 8, no. 3, pp. 883-896, 2014.
-
(2014)
Cell Reports
, vol.8
, Issue.3
, pp. 883-896
-
-
Metzler, K.D.1
Goosmann, C.2
Lubojemska, A.3
Zychlinsky, A.4
Papayannopoulos, V.5
-
65
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
V. Brinkmann, U. Reichard, C. Goosmann et al., "Neutrophil extracellular traps kill bacteria" Science, vol. 303, no. 5663, pp. 1532-1535, 2004.
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1532-1535
-
-
Brinkmann, V.1
Reichard, U.2
Goosmann, C.3
-
66
-
-
78649735324
-
Medical progress: Airway mucus function and dysfunction
-
J. V. Fahy and B. F. Dickey, "Medical progress: airway mucus function and dysfunction" The New England Journal of Medicine, vol. 363, no. 23, pp. 2233-2247, 2010.
-
(2010)
The New England Journal of Medicine
, vol.363
, Issue.23
, pp. 2233-2247
-
-
Fahy, J.V.1
Dickey, B.F.2
-
67
-
-
84863798116
-
Influence of DNA on the activities and inhibition of neutrophil serine proteases in cystic fibrosis sputum
-
A. V. Dubois, A. Gauthier, D. Brea et al., "Influence of DNA on the activities and inhibition of neutrophil serine proteases in cystic fibrosis sputum" American Journal of Respiratory Cell and Molecular Biology, vol. 47, no. 1, pp. 80-86, 2012.
-
(2012)
American Journal of Respiratory Cell and Molecular Biology
, vol.47
, Issue.1
, pp. 80-86
-
-
Dubois, A.V.1
Gauthier, A.2
Brea, D.3
-
68
-
-
84884655341
-
Poly-L-lysine compacts DNA, kills bacteria, and improves protease inhibition in cystic fibrosis sputum
-
A.V. Dubois, P. Midoux, D. Gras et al., "Poly-L-lysine compacts DNA, kills bacteria, and improves protease inhibition in cystic fibrosis sputum" The American Journal of Respiratory and Critical Care Medicine, vol. 188, no. 6, pp. 703-709, 2013.
-
(2013)
The American Journal of Respiratory and Critical Care Medicine
, vol.188
, Issue.6
, pp. 703-709
-
-
Dubois, A.V.1
Midoux, P.2
Gras, D.3
-
69
-
-
0027248335
-
Localization of the gene encoding proteinase-3 (the Wegener's granulomatosis autoantigen) to human chromosome band 19p13.3
-
A. B. Sturrock, R. Espinosa III, J. R. Hoidal, and M. M. Le Beau, "Localization of the gene encoding proteinase-3 (the Wegener's granulomatosis autoantigen) to human chromosome band 19p13.3" Cytogenetics and Cell Genetics, vol. 64, no. 1, pp. 33-34, 1993.
-
(1993)
Cytogenetics and Cell Genetics
, vol.64
, Issue.1
, pp. 33-34
-
-
Sturrock, A.B.1
Espinosa, R.2
Hoidal, J.R.3
Le Beau, M.M.4
-
70
-
-
0024432516
-
Wegener's granulomatosis autoantibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils
-
R. Goldschmeding, C. E. van der Schoot, D. ten Bokkel Huinink et al., "Wegener's granulomatosis autoantibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils" Journal of Clinical Investigation, vol. 84, no. 5, pp. 1577-1587, 1989.
-
(1989)
Journal of Clinical Investigation
, vol.84
, Issue.5
, pp. 1577-1587
-
-
Goldschmeding, R.1
Van Der Schoot, C.E.2
Ten Bokkel Huinink, D.3
-
71
-
-
0034667542
-
Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-And leaves RANTES and MCP-2 intact
-
P. E. van den Steen, P. Proost, A. Wuyts, J. Van Damme, and G. Opdenakker, "Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-And leaves RANTES and MCP-2 intact" Blood, vol. 96, no. 8, pp. 2673-2681, 2000.
-
(2000)
Blood
, vol.96
, Issue.8
, pp. 2673-2681
-
-
Van Den Steen, P.E.1
Proost, P.2
Wuyts, A.3
Van Damme, J.4
Opdenakker, G.5
-
72
-
-
82755161948
-
Cysteine cathepsins: From structure, function and regulation to new frontiers
-
V. Turk, V. Stoka, O. Vasiljeva et al., "Cysteine cathepsins: from structure, function and regulation to new frontiers" Biochimica et Biophysica Acta, vol. 1824, no. 1, pp. 68-88, 2012.
-
(2012)
Biochimica et Biophysica Acta
, vol.1824
, Issue.1
, pp. 68-88
-
-
Turk, V.1
Stoka, V.2
Vasiljeva, O.3
-
73
-
-
0026074943
-
Zymogen activation specificity and genomic structures of human neutrophil elastase and cathepsin G reveal a new branch of the chymotrypsinogen superfamily of serine proteinases
-
G. Salvesen and J. J. Enghild, "Zymogen activation specificity and genomic structures of human neutrophil elastase and cathepsin G reveal a new branch of the chymotrypsinogen superfamily of serine proteinases" Biomedica Biochimica Acta, vol. 50, no. 4-6, pp. 665-671, 1991.
-
(1991)
Biomedica Biochimica Acta
, vol.50
, Issue.4-6
, pp. 665-671
-
-
Salvesen, G.1
Enghild, J.J.2
-
74
-
-
1942437649
-
Linkage of neutrophil serine proteases and decreased surfactant protein-A (SP-A) levels in inflammatory lung disease
-
F. Rubio, J. Cooley, F. J. Accurso, and E. Remold-O'Donnell, "Linkage of neutrophil serine proteases and decreased surfactant protein-A (SP-A) levels in inflammatory lung disease" Thorax, vol. 59, no. 4, pp. 318-323, 2004.
-
(2004)
Thorax
, vol.59
, Issue.4
, pp. 318-323
-
-
Rubio, F.1
Cooley, J.2
Accurso, F.J.3
Remold-O'donnell, E.4
-
75
-
-
0000056632
-
The whey acidic protein family: A new signature motif and three-dimensional structure by comparative modeling
-
S. Ranganathan, K. J. Simpson, D. C. Shaw, and K. R. Nicholas, "The whey acidic protein family: a new signature motif and three-dimensional structure by comparative modeling" Journal of Molecular Graphics and Modelling, vol. 17, no. 2, pp. 106-113, 1999.
-
(1999)
Journal of Molecular Graphics and Modelling
, vol.17
, Issue.2
, pp. 106-113
-
-
Ranganathan, S.1
Simpson, K.J.2
Shaw, D.C.3
Nicholas, K.R.4
-
76
-
-
0037113123
-
A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein
-
A. Clauss, H. Lilja, and A. Lundwall, "A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein" The Biochemical Journal, vol. 368, no. 1, pp. 233-242, 2002.
-
(2002)
The Biochemical Journal
, vol.368
, Issue.1
, pp. 233-242
-
-
Clauss, A.1
Lilja, H.2
Lundwall, A.3
-
77
-
-
80053364868
-
SLPI and elafin: Multifunctional antiproteases of the WFDC family
-
A. Scott, S. Weldon, and C. C. Taggart, "SLPI and elafin: multifunctional antiproteases of the WFDC family" Biochemical Society Transactions, vol. 39, no. 5, pp. 1437-1440, 2011.
-
(2011)
Biochemical Society Transactions
, vol.39
, Issue.5
, pp. 1437-1440
-
-
Scott, A.1
Weldon, S.2
Taggart, C.C.3
-
78
-
-
0022479785
-
The acid-stable proteinase inhibitor of human mucous secretions (HUSI-I, antileukoprotease). Complete amino acid sequence as revealed by protein and cDNA sequencing and structural homology to whey proteins and Red Sea turtle proteinase inhibitor
-
U. Seemller, M. Arnhold, H. Fritz et al., "The acid-stable proteinase inhibitor of human mucous secretions (HUSI-I, antileukoprotease). Complete amino acid sequence as revealed by protein and cDNA sequencing and structural homology to whey proteins and Red Sea turtle proteinase inhibitor" FEBS Letters, vol. 199, no. 1, pp. 43-48, 1986.
-
(1986)
FEBS Letters
, vol.199
, Issue.1
, pp. 43-48
-
-
Seemller, U.1
Arnhold, M.2
Fritz, H.3
-
79
-
-
0026751871
-
The serineprotease inhibitor of cartilage matrix is not a chondrocytic gene product
-
B. Bohm, T. Aigner, R. Kinne, and H. Burkhardt, "The serineprotease inhibitor of cartilage matrix is not a chondrocytic gene product" European Journal of Biochemistry, vol. 207, no. 2, pp. 773-779, 1992.
-
(1992)
European Journal of Biochemistry
, vol.207
, Issue.2
, pp. 773-779
-
-
Bohm, B.1
Aigner, T.2
Kinne, R.3
Burkhardt, H.4
-
80
-
-
0033977041
-
Regulation of SLPI and elafin release from bronchial epithelial cells by neutrophil defensins
-
S. van Wetering, A. C. van der Linden, M. A. J. A. van Sterkenburg et al., "Regulation of SLPI and elafin release from bronchial epithelial cells by neutrophil defensins"TheAmerican Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 278, no. 1, pp. L51-L58, 2000.
-
(2000)
The American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.278
, Issue.1
, pp. L51-L58
-
-
Van Wetering, S.1
Van Der Linden, A.C.2
Van Sterkenburg, M.A.J.A.3
-
81
-
-
0030941175
-
Secretory leukocyte protease inhibitor: Amacrophage product induced by and antagonistic to bacterial lipopolysaccharide
-
F.-Y. Jin, C. Nathan, D. Radzioch, and A. Ding, "Secretory leukocyte protease inhibitor: amacrophage product induced by and antagonistic to bacterial lipopolysaccharide" Cell, vol. 88, no. 3, pp. 417-426, 1997.
-
(1997)
Cell
, vol.88
, Issue.3
, pp. 417-426
-
-
Jin, F.-Y.1
Nathan, C.2
Radzioch, D.3
Ding, A.4
-
82
-
-
0031577718
-
Pseudomonas aeruginosa lipopolysaccharide induces CF-like alteration of protein secretion by human tracheal gland cells
-
W. Kammouni, C. Figarella, N. Baeza, S. Marchand, and M. D. Merten, "Pseudomonas aeruginosa lipopolysaccharide induces CF-like alteration of protein secretion by human tracheal gland cells" Biochemical and Biophysical Research Communications, vol. 241, no. 2, pp. 305-311, 1997.
-
(1997)
Biochemical and Biophysical Research Communications
, vol.241
, Issue.2
, pp. 305-311
-
-
Kammouni, W.1
Figarella, C.2
Baeza, N.3
Marchand, S.4
Merten, M.D.5
-
83
-
-
0035017259
-
Secretion and gene expression of secretory leukocyte protease inhibitor by human airway submucosal glands
-
H. Saitoh, T. Masuda, S. Shimura, T. Fushimi, and K. Shirato, "Secretion and gene expression of secretory leukocyte protease inhibitor by human airway submucosal glands" American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 280, no. 1, pp. L79-L87, 2001.
-
(2001)
American Journal of Physiology-Lung Cellular and Molecular Physiology
, vol.280
, Issue.1
, pp. L79-L87
-
-
Saitoh, H.1
Masuda, T.2
Shimura, S.3
Fushimi, T.4
Shirato, K.5
-
84
-
-
21244442629
-
Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: Identification of earlymediators of host defense
-
J. B. Vos, M. A. van Sterkenburg, K. F. Rabe, J. Schalkwijk, P. S. Hiemstra, and N. A. Datson, "Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of earlymediators of host defense" Physiological Genomics, vol. 21, no. 3, pp. 324-336, 2005.
-
(2005)
Physiological Genomics
, vol.21
, Issue.3
, pp. 324-336
-
-
Vos, J.B.1
Van Sterkenburg, M.A.2
Rabe, K.F.3
Schalkwijk, J.4
Hiemstra, P.S.5
Datson, N.A.6
-
85
-
-
0025274374
-
Location of the protease-inhibitory region of secretory leukocyte protease inhibitor
-
S. P. Eisenberg, K. K. Hale, P. Heimdal, and R. C. Thompson, "Location of the protease-inhibitory region of secretory leukocyte protease inhibitor"The Journal of Biological Chemistry, vol. 265, no. 14, pp. 7976-7981, 1990.
-
(1990)
The Journal of Biological Chemistry
, vol.265
, Issue.14
, pp. 7976-7981
-
-
Eisenberg, S.P.1
Hale, K.K.2
Heimdal, P.3
Thompson, R.C.4
-
86
-
-
29144439305
-
Secretory leucoprotease inhibitor binds to NF-B binding sites in monocytes and inhibits p65 binding
-
C. C. Taggart, S.-A. Cryan, S. Weldon et al., "Secretory leucoprotease inhibitor binds to NF-B binding sites in monocytes and inhibits p65 binding"The Journal of ExperimentalMedicine, vol. 202, no. 12, pp. 1659-1668, 2005.
-
(2005)
The Journal of ExperimentalMedicine
, vol.202
, Issue.12
, pp. 1659-1668
-
-
Taggart, C.C.1
Cryan, S.-A.2
Weldon, S.3
-
87
-
-
0032590012
-
Inhibition of NF-B activation and augmentation of IB by secretory leukocyte protease inhibitor during lung inflammation
-
A. B. Lentsch, J. A. Jordan, B. J. Czermak et al., "Inhibition of NF-B activation and augmentation of IB by secretory leukocyte protease inhibitor during lung inflammation" The American Journal of Pathology, vol. 154, no. 1, pp. 239-247, 1999.
-
(1999)
The American Journal of Pathology
, vol.154
, Issue.1
, pp. 239-247
-
-
Lentsch, A.B.1
Jordan, J.A.2
Czermak, B.J.3
-
88
-
-
0037072766
-
Secretory leucoprotease inhibitor prevents lipopolysaccharideinduced IB degradationwithout affecting phosphorylation or ubiquitination
-
C. C. Taggart, C. M. Greene, N. G. McElvaney, and S. O'Neill, "Secretory leucoprotease inhibitor prevents lipopolysaccharideinduced IB degradationwithout affecting phosphorylation or ubiquitination"The Journal of Biological Chemistry, vol. 277, no. 37, pp. 33648-33653, 2002.
-
(2002)
The Journal of Biological Chemistry
, vol.277
, Issue.37
, pp. 33648-33653
-
-
Taggart, C.C.1
Greene, C.M.2
McElvaney, N.G.3
O'neill, S.4
-
89
-
-
0035823570
-
Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor
-
C. C. Taggart, G. J. Lowe, C. M. Greene et al., "Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor" Journal of Biological Chemistry, vol. 276, no. 36, pp. 33345-33352, 2001.
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.36
, pp. 33345-33352
-
-
Taggart, C.C.1
Lowe, G.J.2
Greene, C.M.3
-
90
-
-
76249114693
-
Decreased levels of secretory leucoprotease inhibitor in the Pseudomonasinfected cystic fibrosis lung are due to neutrophil elastase degradation
-
S. Weldon, P. McNally, N. G. McElvaney et al., "Decreased levels of secretory leucoprotease inhibitor in the Pseudomonasinfected cystic fibrosis lung are due to neutrophil elastase degradation" Journal of Immunology, vol. 183, no. 12, pp. 8148-8156, 2009.
-
(2009)
Journal of Immunology
, vol.183
, Issue.12
, pp. 8148-8156
-
-
Weldon, S.1
McNally, P.2
McElvaney, N.G.3
-
91
-
-
0027581925
-
Characterization and gene sequence of the precursor of elafin, an elastase-specific inhibitor in bronchial secretions
-
J. M. Sallenave and A. Silva, "Characterization and gene sequence of the precursor of elafin, an elastase-specific inhibitor in bronchial secretions" American Journal of Respiratory Cell and Molecular Biology, vol. 8, no. 4, pp. 439-445, 1993.
-
(1993)
American Journal of Respiratory Cell and Molecular Biology
, vol.8
, Issue.4
, pp. 439-445
-
-
Sallenave, J.M.1
Silva, A.2
-
92
-
-
28244491162
-
Elafin and its precursor trappin-2 still inhibit neutrophil serine proteinases when they are covalently bound to extracellular matrix proteins by tissue transglutaminase
-
N. Guyot, M.-L. Zani, M.-C. Maurel, S. Dallet-Choisy, and T. Moreau, "Elafin and its precursor trappin-2 still inhibit neutrophil serine proteinases when they are covalently bound to extracellular matrix proteins by tissue transglutaminase" Biochemistry, vol. 44, no. 47, pp. 15610-15618, 2005.
-
(2005)
Biochemistry
, vol.44
, Issue.47
, pp. 15610-15618
-
-
Guyot, N.1
Zani, M.-L.2
Maurel, M.-C.3
Dallet-Choisy, S.4
Moreau, T.5
-
93
-
-
0025168332
-
Elafin: An elastase-specific inhibitor of human skin. Purification, characterization, and complete amino acid sequence
-
O. Wiedow, J. M. Schrder, H. Gregory, J. A. Young, and E. Christophers, "Elafin: an elastase-specific inhibitor of human skin. Purification, characterization, and complete amino acid sequence" The Journal of Biological Chemistry, vol. 265, no. 25, pp. 14791-14795, 1990.
-
(1990)
The Journal of Biological Chemistry
, vol.265
, Issue.25
, pp. 14791-14795
-
-
Wiedow, O.1
Schrder, J.M.2
Gregory, H.3
Young, J.A.4
Christophers, E.5
-
94
-
-
0028204523
-
Elastase inhibitor elafin is a new type of proteinase inhibitor which has a transglutaminasemediated anchoring sequence termed 'cementoin'
-
K. Nara, S. Ito, T. Ito et al., "Elastase inhibitor elafin is a new type of proteinase inhibitor which has a transglutaminasemediated anchoring sequence termed 'cementoin'" Journal of Biochemistry, vol. 115, no. 3, pp. 441-448, 1994.
-
(1994)
Journal of Biochemistry
, vol.115
, Issue.3
, pp. 441-448
-
-
Nara, K.1
Ito, S.2
Ito, T.3
-
95
-
-
0034581627
-
The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung disease
-
J.-M. Sallenave, "The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung disease" Respiratory Research, vol. 1, no. 2, pp. 87-92, 2000.
-
(2000)
Respiratory Research
, vol.1
, Issue.2
, pp. 87-92
-
-
Sallenave, J.-M.1
-
96
-
-
33845953446
-
Elafin prevents lipopolysaccharideinduced AP-1 and NF-B activation via an effect on the ubiquitin-proteasome pathway
-
M.W. Butler, I. Robertson, C.M. Greene, S. J.O'Neill, C. C. Taggart, andN. G. McElvaney, "Elafin prevents lipopolysaccharideinduced AP-1 and NF-B activation via an effect on the ubiquitin-proteasome pathway"The Journal of Biological Chemistry, vol. 281, no. 46, pp. 34730-34735, 2006.
-
(2006)
The Journal of Biological Chemistry
, vol.281
, Issue.46
, pp. 34730-34735
-
-
Butler, M.W.1
Robertson, I.2
Greene, C.M.3
Oneill, S.4
Taggart, N.G.5
McElvaney, C.C.6
-
97
-
-
0036661152
-
Anti-inflammatory effect of preelafin in lipopolysaccharide-induced acute lung inflammation
-
E. Vachon, Y. Bourbonnais, C. D. Bingle, S. J. Rowe, M. F. Janelle, and G. M. Tremblay, "Anti-inflammatory effect of preelafin in lipopolysaccharide-induced acute lung inflammation" Biological Chemistry, vol. 383, no. 7-8, pp. 1249-1256, 2002.
-
(2002)
Biological Chemistry
, vol.383
, Issue.7-8
, pp. 1249-1256
-
-
Vachon, E.1
Bourbonnais, Y.2
Bingle, C.D.3
Rowe, S.J.4
Janelle, M.F.5
Tremblay, G.M.6
-
98
-
-
0036170699
-
Inhibition of human neutrophil elastase-induced acute lung injury in hamsters by recombinant human pre-elafin (trappin-2)
-
G. M. Tremblay, E. Vachon, C. Larouche, and Y. Bourbonnais, "Inhibition of human neutrophil elastase-induced acute lung injury in hamsters by recombinant human pre-elafin (trappin-2)" Chest, vol. 121, no. 2, pp. 582-588, 2002.
-
(2002)
Chest
, vol.121
, Issue.2
, pp. 582-588
-
-
Tremblay, G.M.1
Vachon, E.2
Larouche, C.3
Bourbonnais, Y.4
-
99
-
-
57749104104
-
Elafin, an elastasespecific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis
-
N. Guyot, M. W. Butler, P. McNally et al., "Elafin, an elastasespecific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis" The Journal of Biological Chemistry, vol. 283, no.47, pp. 32377-32385, 2008.
-
(2008)
The Journal of Biological Chemistry
, vol.283
, Issue.47
, pp. 32377-32385
-
-
Guyot, N.1
Butler, M.W.2
McNally, P.3
-
100
-
-
77956627266
-
Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases
-
N. Guyot, G. Bergsson, M.W. Butler et al., "Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases" Biological Chemistry, vol. 391, no. 6, pp. 705-716, 2010.
-
(2010)
Biological Chemistry
, vol.391
, Issue.6
, pp. 705-716
-
-
Guyot, N.1
Bergsson, G.2
Butler, M.W.3
-
101
-
-
84920682300
-
A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation
-
D. M. Small, M. L. Zani, D. J. Quinn et al., "A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation"MolecularTherapy, vol. 23, no. 1, pp. 24-31, 2014.
-
(2014)
MolecularTherapy
, vol.23
, Issue.1
, pp. 24-31
-
-
Small, D.M.1
Zani, M.L.2
Quinn, D.J.3
-
102
-
-
0029969053
-
Antibacterial activity of antileukoprotease
-
P. S. Hiemstra, R. J. Maassen, J. Stolk, R. Heinzel-Wieland, G. J. Steffens, and J. H. Dijkman, "Antibacterial activity of antileukoprotease" Infection and Immunity, vol. 64, no. 11, pp. 4520-4524, 1996.
-
(1996)
Infection and Immunity
, vol.64
, Issue.11
, pp. 4520-4524
-
-
Hiemstra, P.S.1
Maassen, R.J.2
Stolk, J.3
Heinzel-Wieland, R.4
Steffens, G.J.5
Dijkman, J.H.6
-
103
-
-
0033003889
-
Elafin (elastase-specific inhibitor) has antimicrobial activity against Gram-positive and Gram-negative respiratory pathogens
-
A. J. Simpson, A. I. Maxwell, J. R. W. Govan, C. Haslett, and J.-M. Sallenave, "Elafin (elastase-specific inhibitor) has antimicrobial activity against Gram-positive and Gram-negative respiratory pathogens" FEBS Letters, vol. 452, no. 3, pp. 309-313, 1999.
-
(1999)
FEBS Letters
, vol.452
, Issue.3
, pp. 309-313
-
-
Simpson, A.J.1
Maxwell, A.I.2
Govan, J.R.W.3
Haslett, C.4
Sallenave, J.-M.5
-
104
-
-
77957593445
-
Structural and antimicrobial properties of human pre-elafin/trappin-2 and derived peptides against Pseudomonas aeruginosa
-
Article 253
-
A. Bellemare, N. Vernoux, S. Morin, S.M. Gagn, and Y. Bourbonnais, "Structural and antimicrobial properties of human pre-elafin/trappin-2 and derived peptides against Pseudomonas aeruginosa" BMC Microbiology, vol. 10, article 253, 2010.
-
(2010)
BMC Microbiology
, vol.10
-
-
Bellemare, A.1
Vernoux, N.2
Morin, S.3
Gagn, S.M.4
Bourbonnais, Y.5
-
105
-
-
0019159424
-
Limited proteolysis by macrophage elastase inactivates human 1-proteinase inhibitor"The
-
M. J. Banda, E. J. Clark, and Z. Werb, "Limited proteolysis by macrophage elastase inactivates human 1-proteinase inhibitor"The Journal of Experimental Medicine, vol. 152, no. 6, pp. 1563-1570, 1980.
-
(1980)
Journal of Experimental Medicine
, vol.152
, Issue.6
, pp. 1563-1570
-
-
Banda, M.J.1
Clark, E.J.2
Werb, Z.3
-
106
-
-
0023886316
-
1-Proteinase inhibitor is a neutrophil chemoattractant after proteolytic inactivation by macrophage elastase
-
M. J. Banda, A. G. Rice, G. L. Griffin, and R. M. Senior, "1-Proteinase inhibitor is a neutrophil chemoattractant after proteolytic inactivation by macrophage elastase" Journal of Biological Chemistry, vol. 263, no. 9, pp. 4481-4484, 1988.
-
(1988)
Journal of Biological Chemistry
, vol.263
, Issue.9
, pp. 4481-4484
-
-
Banda, M.J.1
Rice, A.G.2
Griffin, G.L.3
Senior, R.M.4
-
107
-
-
34547902512
-
1-Antitrypsin suppresses TNF-And MMP-12 production by cigarette smoke-stimulated macrophages
-
A. Churg, X. Wang, R.D. Wang, S. C. Meixner, E. L. G. Pryzdial, and J. L. Wright, "1-Antitrypsin suppresses TNF-And MMP-12 production by cigarette smoke-stimulated macrophages" American Journal of Respiratory Cell andMolecular Biology, vol. 37, no. 2, pp. 144-151, 2007.
-
(2007)
American Journal of Respiratory Cell AndMolecular Biology
, vol.37
, Issue.2
, pp. 144-151
-
-
Churg, A.1
Wang, X.2
Wang, R.D.3
Meixner, S.C.4
Pryzdial, E.L.G.5
Wright, J.L.6
-
108
-
-
0024431647
-
Antileukoprotease is associated with elastin fibers in the extracellular matrix of the human lung: An immunoelectron microscopic study
-
J. A. Kramps, A. H. T. Te Boekhorst, J. A. M. Fransen, L. A. Ginsel, and J. H. Dijkman, "Antileukoprotease is associated with elastin fibers in the extracellular matrix of the human lung: an immunoelectron microscopic study" The American Review of Respiratory Disease, vol. 140, no. 2, pp. 471-476, 1989.
-
(1989)
The American Review of Respiratory Disease
, vol.140
, Issue.2
, pp. 471-476
-
-
Kramps, J.A.1
Te Boekhorst, A.H.T.2
Fransen, J.A.M.3
Ginsel, L.A.4
Dijkman, J.H.5
-
109
-
-
0022472015
-
Expression of the alpha-1-Antitrypsin gene in mononuclear phagocytes of normal and alpha-1-Antitrypsin-deficient individuals
-
J.-F. Mornex, A. Chytil-Weir, Y. Martinet, M. Courtney, J. P. LeCocq, and R. G. Crystal, "Expression of the alpha-1-Antitrypsin gene in mononuclear phagocytes of normal and alpha-1-Antitrypsin-deficient individuals" The Journal of Clinical Investigation, vol. 77, no. 6, pp. 1952-1961, 1986.
-
(1986)
The Journal of Clinical Investigation
, vol.77
, Issue.6
, pp. 1952-1961
-
-
Mornex, J.-F.1
Chytil-Weir, A.2
Martinet, Y.3
Courtney, M.4
Lecocq, J.P.5
Crystal, R.G.6
-
110
-
-
0025833475
-
Human neutrophils express the 1-Antitrypsin gene and produce 1-Antitrypsin
-
R. M. du Bois, J.-F. Bernaudin, P. Paakko et al., "Human neutrophils express the 1-Antitrypsin gene and produce 1-Antitrypsin" Blood, vol. 77, no. 12, pp. 2724-2730, 1991.
-
(1991)
Blood
, vol.77
, Issue.12
, pp. 2724-2730
-
-
Du Bois, R.M.1
Bernaudin, J.-F.2
Paakko, P.3
-
111
-
-
31544470902
-
Safety and efficacy of recombinant alpha1-Antitrypsin therapy in cystic fibrosis
-
S. L. Martin, D. Downey, D. Bilton, M. T. Keogan, J. Edgar, and J. S. Elborn, "Safety and efficacy of recombinant alpha1-Antitrypsin therapy in cystic fibrosis" Pediatric Pulmonology, vol. 41, no. 2, pp. 177-183, 2006.
-
(2006)
Pediatric Pulmonology
, vol.41
, Issue.2
, pp. 177-183
-
-
Martin, S.L.1
Downey, D.2
Bilton, D.3
Keogan, M.T.4
Edgar, J.5
Elborn, J.S.6
-
112
-
-
33846907545
-
Alpha1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients
-
M. Griese, P. Latzin, M. Kappler et al., "Alpha1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients" The European Respiratory Journal, vol. 29, no. 2, pp. 240-250, 2007.
-
(2007)
The European Respiratory Journal
, vol.29
, Issue.2
, pp. 240-250
-
-
Griese, M.1
Latzin, P.2
Kappler, M.3
-
113
-
-
84858294319
-
Oxidative stress and antioxidant therapy in cystic fibrosis
-
F. Galli, A. Battistoni, R. Gambari et al., "Oxidative stress and antioxidant therapy in cystic fibrosis" Biochimica et Biophysica Acta-Molecular Basis of Disease, vol. 1822, no. 5, pp. 690-713, 2012.
-
(2012)
Biochimica et Biophysica Acta-Molecular Basis of Disease
, vol.1822
, Issue.5
, pp. 690-713
-
-
Galli, F.1
Battistoni, A.2
Gambari, R.3
-
114
-
-
0025708374
-
Human neutrophil collagenase cleaves alpha 1-Antitrypsin
-
J. Michaelis, M. C. Vissers, and C. C. Winterbourn, "Human neutrophil collagenase cleaves alpha 1-Antitrypsin" The Biochemical Journal, vol. 270, no. 3, pp. 809-814, 1990.
-
(1990)
The Biochemical Journal
, vol.270
, Issue.3
, pp. 809-814
-
-
Michaelis, J.1
Vissers, M.C.2
Winterbourn, C.C.3
-
115
-
-
0028201849
-
Proteolysis of human native and oxidised alpha1-proteinase inhibitor by matrulysin and stromelysin
-
Z. Zhang, P. G. Winyard, K. Chidwick et al., "Proteolysis of human native and oxidised alpha1-proteinase inhibitor by matrulysin and stromelysin" Biochimica et Biophysica Acta, vol. 1199, no. 2, pp. 224-228, 1994.
-
(1994)
Biochimica et Biophysica Acta
, vol.1199
, Issue.2
, pp. 224-228
-
-
Zhang, Z.1
Winyard, P.G.2
Chidwick, K.3
-
116
-
-
0026471308
-
Protease inhibitor display M13 phage: Selection of high-Affinity neutrophil elastase inhibitors
-
B. L. Roberts, W. Markland, K. Siranosian, M. J. Saxena, S. K. Guterman, and R. C. Ladner, "Protease inhibitor display M13 phage: selection of high-Affinity neutrophil elastase inhibitors" Gene, vol. 121, no. 1, pp. 9-15, 1992.
-
(1992)
Gene
, vol.121
, Issue.1
, pp. 9-15
-
-
Roberts, B.L.1
Markland, W.2
Siranosian, K.3
Saxena, M.J.4
Guterman, S.K.5
Ladner, R.C.6
-
117
-
-
0036008396
-
Protectionagainst acute lung injury by intravenous or intratracheal pretreatment with EPI-HNE-4, a new potent neutrophil elastase inhibitor
-
C. Delacourt, S. Herigault, C. Delclaux et al., "Protectionagainst acute lung injury by intravenous or intratracheal pretreatment with EPI-HNE-4, a new potent neutrophil elastase inhibitor" American Journal of Respiratory Cell andMolecular Biology, vol. 26, no. 3, pp. 290-297, 2002.
-
(2002)
American Journal of Respiratory Cell AndMolecular Biology
, vol.26
, Issue.3
, pp. 290-297
-
-
Delacourt, C.1
Herigault, S.2
Delclaux, C.3
-
118
-
-
84862506566
-
Anti-inflammatory effects of DX-890, a human neutrophil elastase inhibitor
-
F. K. Dunlevy, S. L. Martin, F. de Courcey, J. S. Elborn, and M. Ennis, "Anti-inflammatory effects of DX-890, a human neutrophil elastase inhibitor" Journal of Cystic Fibrosis, vol. 11, no. 4, pp. 300-304, 2012.
-
(2012)
Journal of Cystic Fibrosis
, vol.11
, Issue.4
, pp. 300-304
-
-
Dunlevy, F.K.1
Martin, S.L.2
De Courcey, F.3
Elborn, J.S.4
Ennis, M.5
-
119
-
-
33745941917
-
EPI-hNE4, a proteolysis-resistant inhibitor of human neutrophil elastase and potential anti-inflammatory drug for treating cystic fibrosis
-
S. Attucci, A. Gauthier, B. Korkmaz et al., "EPI-hNE4, a proteolysis-resistant inhibitor of human neutrophil elastase and potential anti-inflammatory drug for treating cystic fibrosis" Journal of Pharmacology and Experimental Therapeutics, vol. 318, no. 2, pp. 803-809, 2006.
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.318
, Issue.2
, pp. 803-809
-
-
Attucci, S.1
Gauthier, A.2
Korkmaz, B.3
-
120
-
-
80053169347
-
AZD9668: Pharmacological characterization of a novel oral inhibitor of neutrophil elastase
-
T. Stevens, K. Ekholm, M. Granse et al., "AZD9668: pharmacological characterization of a novel oral inhibitor of neutrophil elastase" The Journal of Pharmacology and Experimental Therapeutics, vol. 339, no. 1, pp. 313-320, 2011.
-
(2011)
The Journal of Pharmacology and Experimental Therapeutics
, vol.339
, Issue.1
, pp. 313-320
-
-
Stevens, T.1
Ekholm, K.2
Granse, M.3
-
121
-
-
84875241103
-
Phase II study of a neutrophil elastase inhibitor (AZD9668) in patients with bronchiectasis
-
R. Stockley, A. De Soyza, K. Gunawardena et al., "Phase II study of a neutrophil elastase inhibitor (AZD9668) in patients with bronchiectasis" Respiratory Medicine, vol. 107, no. 4, pp. 524-533, 2013.
-
(2013)
Respiratory Medicine
, vol.107
, Issue.4
, pp. 524-533
-
-
Stockley, R.1
De Soyza, A.2
Gunawardena, K.3
-
122
-
-
84859373133
-
A randomised, placebo-controlled, dosefinding study of AZD9668, an oral inhibitor of neutrophil elastase, in patients with chronic obstructive pulmonary disease treated with tiotropium
-
C. Vogelmeier, T. O. Aquino, C. D. O'Brien, J. Perrett, and K. A. Gunawardena, "A randomised, placebo-controlled, dosefinding study of AZD9668, an oral inhibitor of neutrophil elastase, in patients with chronic obstructive pulmonary disease treated with tiotropium" COPD: Journal of Chronic Obstructive Pulmonary Disease, vol. 9, no. 2, pp. 111-120, 2012.
-
(2012)
COPD: Journal of Chronic Obstructive Pulmonary Disease
, vol.9
, Issue.2
, pp. 111-120
-
-
Vogelmeier, C.1
Aquino, T.O.2
O'brien, C.D.3
Perrett, J.4
Gunawardena, K.A.5
-
123
-
-
84867131143
-
Efficacy, safety and effect on biomarkers of AZD9668 in cystic fibrosis
-
J. S. Elborn, J. Perrett, K. Forsman-Semb, J. Marks-Konczalik, K. Gunawardena, and N. Entwistle, "Efficacy, safety and effect on biomarkers of AZD9668 in cystic fibrosis" European Respiratory Journal, vol. 40, no. 4, pp. 969-976, 2012.
-
(2012)
European Respiratory Journal
, vol.40
, Issue.4
, pp. 969-976
-
-
Elborn, J.S.1
Perrett, J.2
Forsman-Semb, K.3
Marks-Konczalik, J.4
Gunawardena, K.5
Entwistle, N.6
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