Impaired mucus clearance exacerbates allergen-induced type 2 airway inflammation in juvenile mice

Journal of Allergy and Clinical Immunology

Volumn 140, Issue 1, 2017, Pages 190-203.e5

  Fritzsching, Benedikt ^a   Hagner, Matthias ^a   Dai, Lu ^a   Christochowitz, Sandra ^a   Agrawal, Raman ^a   van Bodegom, Charlotte ^a   Schmidt, Simone ^a   Schatterny, Jolanthe ^a   Hirtz, Stephanie ^a   Brown, Ryan ^a   Goritzka, Michelle ^a   Duerr, Julia ^a   Zhou Suckow, Zhe ^a   Mall, Marcus A ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

airway epithelium; IL 13; IL 33; mucociliary clearance; Type 2 inflammation

Indexed keywords

AMILORIDE; EPITHELIAL SODIUM CHANNEL; HOUSE DUST ALLERGEN; INTERLEUKIN 13; INTERLEUKIN 33; INTERLEUKIN 4; INTERLEUKIN 5; STAT6 PROTEIN; ALLERGEN; SCNN1B PROTEIN, MOUSE; SODIUM CHANNEL BLOCKING AGENT; STAT6 PROTEIN, MOUSE;

ADAPTIVE IMMUNITY; ADULT; AIRWAY EPITHELIUM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE EXACERBATION; EOSINOPHILIA; GENE DELETION; GOBLET CELL; IMMUNOPATHOGENESIS; INNATE IMMUNITY; JUVENILE; LYMPHOID CELL; MACROPHAGE; MACROPHAGE ACTIVATION; METAPLASIA; MOUSE; MUCOCILIARY CLEARANCE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; TH2 CELL; TRANSGENIC MOUSE; WILD TYPE MOUSE; ANIMAL; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; CELL CULTURE; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; EPITHELIUM CELL; GENETICS; IMMUNOLOGY; LUNG; PATHOPHYSIOLOGY; PYROGLYPHIDAE;

ALLERGENS; AMILORIDE; ANIMALS; ASPERGILLUS FUMIGATUS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; EPITHELIAL SODIUM CHANNELS; INTERLEUKIN-13; LUNG; MICE, TRANSGENIC; MUCOCILIARY CLEARANCE; PYROGLYPHIDAE; SODIUM CHANNEL BLOCKERS; STAT6 TRANSCRIPTION FACTOR;

EID: 85007597333     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2016.09.045     Document Type: Article

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