Airway and lung pathology due to mucosal surface dehydration in β-epithelial Na+ channel-overexpressing mice: Role of TNF-α and IL-4Rα signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment

Journal of Immunology

Volumn 182, Issue 7, 2009, Pages 4357-4367

  Livraghi, Alessandra ^a   Grubb, Barbara R ^a   Hudson, Elizabeth J ^a   Wilkinson, Kristen J ^a   Sheehan, John K ^a   Mall, Marcus A ^b   O'Neal, Wanda K ^a   Boucher, Richard C ^a   Randell, Scott H ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHITINASE; EPITHELIAL SODIUM CHANNEL; EPITHELIAL SODIUM CHANNEL BETA; GLUCOCORTICOID; INTERLEUKIN 4 RECEPTOR ALPHA; PREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; CHEMOKINE; IL4RA PROTEIN, MOUSE; SCNN1B PROTEIN, MOUSE;

ADOLESCENT; AIRWAY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEHYDRATION; DRUG EFFICACY; EOSINOPHILIA; GENE DELETION; INFLAMMATION; LUNG LAVAGE; MACROPHAGE ACTIVATION; MOUSE; NEUTROPHILIA; NEWBORN; NONHUMAN; OBSTRUCTIVE AIRWAY DISEASE; PERINATAL DEVELOPMENT; PRIORITY JOURNAL; TRANSGENIC MOUSE; ANIMAL; CHEMISTRY; DISEASE MODEL; DRUG EFFECT; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; METABOLISM; MUCOSAL IMMUNITY; NEUTROPHIL; PATHOPHYSIOLOGY; PHYSIOLOGY; RESPIRATORY SYSTEM; RESPIRATORY TRACT MUCOSA; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINES; DEHYDRATION; DISEASE MODELS, ANIMAL; EOSINOPHILIA; EPITHELIAL SODIUM CHANNEL; GLUCOCORTICOIDS; IMMUNITY, MUCOSAL; MICE; MICE, TRANSGENIC; NEUTROPHILS; PREDNISOLONE; RECEPTORS, CELL SURFACE; RESPIRATORY MUCOSA; RESPIRATORY SYSTEM; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 64249168940     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802557     Document Type: Article

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