-
1
-
-
84903883904
-
2+-dependent gene expression in response to receptor stimulation
-
CrossRef, PubMed
-
2+-dependent gene expression in response to receptor stimulation. PLoS ONE 2014, 9, e101188. [CrossRef] [PubMed]
-
(2014)
PLoS ONE
, vol.9
-
-
Samanta, K.1
Douglas, S.2
Parekh, A.B.3
-
2
-
-
0035166814
-
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells
-
CrossRef, PubMed
-
Smirnova, E.; Griparic, L.; Shurland, D.L.; van der Bliek, A.M. Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol. Biol. Cell 2001, 12, 2245-2256. [CrossRef] [PubMed]
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2245-2256
-
-
Smirnova, E.1
Griparic, L.2
Shurland, D.L.3
Van Der Bliek, A.M.4
-
3
-
-
22544451586
-
Disruption of fusion results in mitochondrial heterogeneity and dysfunction
-
CrossRef, PubMed
-
Chen, H.; Chomyn, A.; Chan, D.C. Disruption of fusion results in mitochondrial heterogeneity and dysfunction. J. Biol. Chem. 2005, 280, 26185-26192. [CrossRef] [PubMed]
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 26185-26192
-
-
Chen, H.1
Chomyn, A.2
Chan, D.C.3
-
4
-
-
77957798188
-
A lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division
-
CrossRef, PubMed
-
Chang, C.R.; Manlandro, C.M.; Arnoult, D.; Stadler, J.; Posey, A.E.; Hill, R.B.; Blackstone, C. A lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division. J. Biol. Chem. 2010, 285, 32494-32503. [CrossRef] [PubMed]
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 32494-32503
-
-
Chang, C.R.1
Manlandro, C.M.2
Arnoult, D.3
Stadler, J.4
Posey, A.E.5
Hill, R.B.6
Blackstone, C.7
-
5
-
-
84892992099
-
Stress-induced nuclear-to-cytoplasmic translocation of cyclin C promotes mitochondrial fission in yeast
-
CrossRef, PubMed
-
Cooper, K.F.; Khakhina, S.; Kim, S.K.; Strich, R. Stress-induced nuclear-to-cytoplasmic translocation of cyclin C promotes mitochondrial fission in yeast. Dev. Cell 2014, 28, 161-173. [CrossRef] [PubMed]
-
(2014)
Dev. Cell
, vol.28
, pp. 161-173
-
-
Cooper, K.F.1
Khakhina, S.2
Kim, S.K.3
Strich, R.4
-
6
-
-
84866739338
-
Phosphorylation and ubiquitination of dynamin-related proteins (AtDRP3A/3B) synergically regulate mitochondrial proliferation during mitosis
-
CrossRef, PubMed
-
Wang, F.; Liu, P.; Zhang, Q.; Zhu, J.; Chen, T.; Arimura, S.; Tsutsumi, N.; Lin, J. Phosphorylation and ubiquitination of dynamin-related proteins (AtDRP3A/3B) synergically regulate mitochondrial proliferation during mitosis. Plant. J. 2012, 72, 43-56. [CrossRef] [PubMed]
-
(2012)
Plant. J.
, vol.72
, pp. 43-56
-
-
Wang, F.1
Liu, P.2
Zhang, Q.3
Zhu, J.4
Chen, T.5
Arimura, S.6
Tsutsumi, N.7
Lin, J.8
-
7
-
-
84902682341
-
A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission
-
CrossRef, PubMed
-
Macdonald, P.J.; Stepanyants, N.; Mehrotra, N.; Mears, J.A.; Qi, X.; Sesaki, H.; Ramachandran, R. A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission. Mol. Biol. Cell 2014, 25, 1905-1915. [CrossRef] [PubMed]
-
(2014)
Mol. Biol. Cell
, vol.25
, pp. 1905-1915
-
-
Macdonald, P.J.1
Stepanyants, N.2
Mehrotra, N.3
Mears, J.A.4
Qi, X.5
Sesaki, H.6
Ramachandran, R.7
-
8
-
-
84874694989
-
Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress
-
CrossRef, PubMed
-
Qian,W.; Choi, S.; Gibson, G.A.;Watkins, S.C.; Bakkenist, C.J.; van Houten, B. Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress. J. Cell Sci. 2012, 125, 5745-5757. [CrossRef] [PubMed]
-
(2012)
J. Cell Sci.
, vol.125
, pp. 5745-5757
-
-
Qian, W.1
Choi, S.2
Gibson, G.A.3
Watkins, S.C.4
Bakkenist, C.J.5
Van Houten, B.6
-
9
-
-
35148832011
-
Drp1 mediates caspase-independent type III cell death in normal and leukemic cells
-
CrossRef, PubMed
-
Bras, M.; Yuste, V.J.; Roue, G.; Barbier, S.; Sancho, P.; Virely, C.; Rubio, M.; Baudet, S.; Esquerda, J.E.; Merle-Beral, H.; et al. Drp1 mediates caspase-independent type III cell death in normal and leukemic cells. Mol. Cell. Biol. 2007, 27, 7073-7088. [CrossRef] [PubMed]
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 7073-7088
-
-
Bras, M.1
Yuste, V.J.2
Roue, G.3
Barbier, S.4
Sancho, P.5
Virely, C.6
Rubio, M.7
Baudet, S.8
Esquerda, J.E.9
Merle-Beral, H.10
-
10
-
-
77955298543
-
Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1
-
CrossRef, PubMed
-
Chang, C.R.; Blackstone, C. Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1. Ann. N. Y. Acad. Sci. 2010, 1201, 34-39. [CrossRef] [PubMed]
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1201
, pp. 34-39
-
-
Chang, C.R.1
Blackstone, C.2
-
11
-
-
84952879474
-
Distinct splice variants of dynamin-related protein 1 differentially utilize mitochondrial fission factor as an effector of cooperative GTPase activity
-
CrossRef, PubMed
-
Macdonald, P.J.; Francy, C.A.; Stepanyants, N.; Lehman, L.; Baglio, A.; Mears, J.A.; Qi, X.; Ramachandran, R. Distinct splice variants of dynamin-related protein 1 differentially utilize mitochondrial fission factor as an effector of cooperative GTPase activity. J. Biol. Chem. 2016, 291, 493-507. [CrossRef] [PubMed]
-
(2016)
J. Biol. Chem.
, vol.291
, pp. 493-507
-
-
Macdonald, P.J.1
Francy, C.A.2
Stepanyants, N.3
Lehman, L.4
Baglio, A.5
Mears, J.A.6
Qi, X.7
Ramachandran, R.8
-
12
-
-
84989187139
-
Interaction with the effector dynamin-related protein 1 (Drp1) is an ancient function of Rab32 subfamily proteins
-
CrossRef, PubMed
-
Ortiz-Sandoval, C.G.; Hughes, S.C.; Dacks, J.B.; Simmen, T. Interaction with the effector dynamin-related protein 1 (Drp1) is an ancient function of Rab32 subfamily proteins. Cell. Logist. 2014, 4, e986399. [CrossRef] [PubMed]
-
(2014)
Cell. Logist.
, vol.4
-
-
Ortiz-Sandoval, C.G.1
Hughes, S.C.2
Dacks, J.B.3
Simmen, T.4
-
13
-
-
84909992187
-
Cdk1, PKCδ and calcineurin-mediated Drp1 pathway contributes to mitochondrial fission-induced cardiomyocyte death
-
CrossRef, PubMed
-
Zaja, I.; Bai, X.; Liu, Y.; Kikuchi, C.; Dosenovic, S.; Yan, Y.; Canfield, S.G.; Bosnjak, Z.J. Cdk1, PKCδ and calcineurin-mediated Drp1 pathway contributes to mitochondrial fission-induced cardiomyocyte death. Biochem. Biophys. Res. Commun. 2014, 453, 710-721. [CrossRef] [PubMed]
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.453
, pp. 710-721
-
-
Zaja, I.1
Bai, X.2
Liu, Y.3
Kikuchi, C.4
Dosenovic, S.5
Yan, Y.6
Canfield, S.G.7
Bosnjak, Z.J.8
-
14
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
CrossRef, PubMed
-
Twig, G.; Elorza, A.; Molina, A.J.; Mohamed, H.;Wikstrom, J.D.;Walzer, G.; Stiles, L.; Haigh, S.E.; Katz, S.; Las, G.; et al. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J. 2008, 27, 433-446. [CrossRef] [PubMed]
-
(2008)
EMBO J.
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
-
15
-
-
84906993286
-
Optimized two-color super resolution imaging of Drp1 during mitochondrial fission with a slow-switching Dronpa variant
-
CrossRef, PubMed
-
Rosenbloom, A.B.; Lee, S.H.; To, M.; Lee, A.; Shin, J.Y.; Bustamante, C. Optimized two-color super resolution imaging of Drp1 during mitochondrial fission with a slow-switching Dronpa variant. Proc. Natl. Acad. Sci. USA 2014, 111, 13093-13098. [CrossRef] [PubMed]
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 13093-13098
-
-
Rosenbloom, A.B.1
Lee, S.H.2
To, M.3
Lee, A.4
Shin, J.Y.5
Bustamante, C.6
-
16
-
-
84866728707
-
Endoplasmic reticulum-mitochondria contacts: Function of the junction
-
CrossRef, PubMed
-
Rowland, A.A.; Voeltz, G.K. Endoplasmic reticulum-mitochondria contacts: Function of the junction. Nat. Rev. Mol. Cell Biol. 2012, 13, 607-625. [CrossRef] [PubMed]
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 607-625
-
-
Rowland, A.A.1
Voeltz, G.K.2
-
17
-
-
78650167618
-
Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells
-
CrossRef, PubMed
-
Otera, H.; Wang, C.; Cleland, M.M.; Setoguchi, K.; Yokota, S.; Youle, R.J.; Mihara, K. Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells. J. Cell Biol. 2010, 191, 1141-1158. [CrossRef] [PubMed]
-
(2010)
J. Cell Biol.
, vol.191
, pp. 1141-1158
-
-
Otera, H.1
Wang, C.2
Cleland, M.M.3
Setoguchi, K.4
Yokota, S.5
Youle, R.J.6
Mihara, K.7
-
18
-
-
84952893722
-
Dynamin-related protein 1 oligomerization in solution impairs functional interactions with membrane-anchored mitochondrial fission factor
-
CrossRef, PubMed
-
Clinton, R.W.; Francy, C.A.; Ramachandran, R.; Qi, X.; Mears, J.A. Dynamin-related protein 1 oligomerization in solution impairs functional interactions with membrane-anchored mitochondrial fission factor. J. Biol. Chem. 2016, 291, 478-492. [CrossRef] [PubMed]
-
(2016)
J. Biol. Chem.
, vol.291
, pp. 478-492
-
-
Clinton, R.W.1
Francy, C.A.2
Ramachandran, R.3
Qi, X.4
Mears, J.A.5
-
19
-
-
84941425977
-
Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1
-
CrossRef, PubMed
-
Loson, O.C.; Meng, S.; Ngo, H.; Liu, R.; Kaiser, J.T.; Chan, D.C. Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1. Protein Sci. 2015, 24, 386-394. [CrossRef] [PubMed]
-
(2015)
Protein Sci.
, vol.24
, pp. 386-394
-
-
Loson, O.C.1
Meng, S.2
Ngo, H.3
Liu, R.4
Kaiser, J.T.5
Chan, D.C.6
-
20
-
-
79960621726
-
Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission
-
CrossRef, PubMed
-
Zhao, J.; Liu, T.; Jin, S.; Wang, X.; Qu, M.; Uhlen, P.; Tomilin, N.; Shupliakov, O.; Lendahl, U.; Nister, M. Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission. EMBO J. 2011, 30, 2762-2778. [CrossRef] [PubMed]
-
(2011)
EMBO J.
, vol.30
, pp. 2762-2778
-
-
Zhao, J.1
Liu, T.2
Jin, S.3
Wang, X.4
Qu, M.5
Uhlen, P.6
Tomilin, N.7
Shupliakov, O.8
Lendahl, U.9
Nister, M.10
-
21
-
-
84884574238
-
Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission
-
CrossRef, PubMed
-
Palmer, C.S.; Elgass, K.D.; Parton, R.G.; Osellame, L.D.; Stojanovski, D.; Ryan, M.T. Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission. J. Biol. Chem. 2013, 288, 27584-27593. [CrossRef] [PubMed]
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 27584-27593
-
-
Palmer, C.S.1
Elgass, K.D.2
Parton, R.G.3
Osellame, L.D.4
Stojanovski, D.5
Ryan, M.T.6
-
22
-
-
84973449037
-
Drp1, Mff, Fis1, and MiD51 are coordinated to mediate mitochondrial fission during UV irradiation-induced apoptosis
-
CrossRef, PubMed
-
Zhang, Z.; Liu, L.;Wu, S.; Xing, D. Drp1, Mff, Fis1, and MiD51 are coordinated to mediate mitochondrial fission during UV irradiation-induced apoptosis. FASEB J. 2016, 30, 466-476. [CrossRef] [PubMed]
-
(2016)
FASEB J.
, vol.30
, pp. 466-476
-
-
Zhang, Z.1
Liu, L.2
Wu, S.3
Xing, D.4
-
23
-
-
77951199668
-
Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1
-
CrossRef, PubMed
-
Mai, S.; Klinkenberg, M.; Auburger, G.; Bereiter-Hahn, J.; Jendrach, M. Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1. J. Cell Sci. 2010, 123, 917-926. [CrossRef] [PubMed]
-
(2010)
J. Cell Sci.
, vol.123
, pp. 917-926
-
-
Mai, S.1
Klinkenberg, M.2
Auburger, G.3
Bereiter-Hahn, J.4
Jendrach, M.5
-
24
-
-
84976477426
-
Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission
-
CrossRef, PubMed
-
Osellame, L.D.; Singh, A.P.; Stroud, D.A.; Palmer, C.S.; Stojanovski, D.; Ramachandran, R.; Ryan, M.T. Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission. J. Cell Sci. 2016, 129, 2170-2181. [CrossRef] [PubMed]
-
(2016)
J. Cell Sci.
, vol.129
, pp. 2170-2181
-
-
Osellame, L.D.1
Singh, A.P.2
Stroud, D.A.3
Palmer, C.S.4
Stojanovski, D.5
Ramachandran, R.6
Ryan, M.T.7
-
25
-
-
84991721053
-
Coincident phosphatidic acid interaction restrains Drp1 in mitochondrial division
-
CrossRef, PubMed
-
Adachi, Y.; Itoh, K.; Yamada, T.; Cerveny, K.L.; Suzuki, T.L.; Macdonald, P.; Frohman, M.A.; Ramachandran, R.; Iijima, M.; Sesaki, H. Coincident phosphatidic acid interaction restrains Drp1 in mitochondrial division. Mol. Cell 2016, 63, 1034-1043. [CrossRef] [PubMed]
-
(2016)
Mol. Cell
, vol.63
, pp. 1034-1043
-
-
Adachi, Y.1
Itoh, K.2
Yamada, T.3
Cerveny, K.L.4
Suzuki, T.L.5
Macdonald, P.6
Frohman, M.A.7
Ramachandran, R.8
Iijima, M.9
Sesaki, H.10
-
26
-
-
84940403792
-
Cardiolipin’s propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission
-
CrossRef, PubMed
-
Stepanyants, N.; Macdonald, P.J.; Francy, C.A.; Mears, J.A.; Qi, X.; Ramachandran, R. Cardiolipin’s propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission. Mol. Biol. Cell 2015, 26, 3104-3116. [CrossRef] [PubMed]
-
(2015)
Mol. Biol. Cell
, vol.26
, pp. 3104-3116
-
-
Stepanyants, N.1
Macdonald, P.J.2
Francy, C.A.3
Mears, J.A.4
Qi, X.5
Ramachandran, R.6
-
27
-
-
84957922098
-
Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites
-
CrossRef, PubMed
-
Ji,W.K.; Hatch, A.L.; Merrill, R.A.; Strack, S.; Higgs, H.N. Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites. Elife 2015, 4, e11553. [CrossRef] [PubMed]
-
(2015)
Elife
, vol.4
-
-
Ji, W.K.1
Hatch, A.L.2
Merrill, R.A.3
Strack, S.4
Higgs, H.N.5
-
28
-
-
84946778740
-
Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis
-
CrossRef, PubMed
-
Dara, L.; Johnson, H.; Suda, J.;Win, S.; Gaarde,W.; Han, D.; Kaplowitz, N. Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis. Hepatology 2015, 62, 1847-1857. [CrossRef] [PubMed]
-
(2015)
Hepatology
, vol.62
, pp. 1847-1857
-
-
Dara, L.1
Johnson, H.2
Suda, J.3
Win, S.4
Gaarde, W.5
Han, D.6
Kaplowitz, N.7
-
29
-
-
25444514731
-
Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: New implications for Charcot-Marie-Tooth disease
-
CrossRef, PubMed
-
Niemann, A.; Ruegg, M.; La Padula, V.; Schenone, A.; Suter, U. Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: New implications for Charcot-Marie-Tooth disease. J. Cell Biol. 2005, 170, 1067-1078. [CrossRef] [PubMed]
-
(2005)
J. Cell Biol.
, vol.170
, pp. 1067-1078
-
-
Niemann, A.1
Ruegg, M.2
La Padula, V.3
Schenone, A.4
Suter, U.5
-
30
-
-
79955777855
-
A receptor tyrosine kinase inhibitor, tyrphostin A9 induces cancer cell death through Drp1 dependent mitochondria fragmentation
-
CrossRef, PubMed
-
Park, S.J.; Park, Y.J.; Shin, J.H.; Kim, E.S.; Hwang, J.J.; Jin, D.H.; Kim, J.C.; Cho, D.H. A receptor tyrosine kinase inhibitor, tyrphostin A9 induces cancer cell death through Drp1 dependent mitochondria fragmentation. Biochem. Biophys. Res. Commun. 2011, 408, 465-470. [CrossRef] [PubMed]
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.408
, pp. 465-470
-
-
Park, S.J.1
Park, Y.J.2
Shin, J.H.3
Kim, E.S.4
Hwang, J.J.5
Jin, D.H.6
Kim, J.C.7
Cho, D.H.8
-
31
-
-
79953132685
-
Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion
-
CrossRef, PubMed
-
Anton, F.; Fres, J.M.; Schauss, A.; Pinson, B.; Praefcke, G.J.; Langer, T.; Escobar-Henriques, M. Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion. J. Cell Sci. 2011, 124, 1126-1135. [CrossRef] [PubMed]
-
(2011)
J. Cell Sci.
, vol.124
, pp. 1126-1135
-
-
Anton, F.1
Fres, J.M.2
Schauss, A.3
Pinson, B.4
Praefcke, G.J.5
Langer, T.6
Escobar-Henriques, M.7
-
32
-
-
84960345982
-
Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology
-
CrossRef, PubMed
-
Zhang, C.; Shi, Z.; Zhang, L.; Zhou, Z.; Zheng, X.; Liu, G.; Bu, G.; Fraser, P.E.; Xu, H.; Zhang, Y.W. Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology. J. Cell Sci. 2016, 129, 994-1002. [CrossRef] [PubMed]
-
(2016)
J. Cell Sci.
, vol.129
, pp. 994-1002
-
-
Zhang, C.1
Shi, Z.2
Zhang, L.3
Zhou, Z.4
Zheng, X.5
Liu, G.6
Bu, G.7
Fraser, P.E.8
Xu, H.9
Zhang, Y.W.10
-
33
-
-
84861793592
-
Mitochondrial chaperone DnaJA3 induces Drp1-dependent mitochondrial fragmentation
-
CrossRef, PubMed
-
Elwi, A.N.; Lee, B.; Meijndert, H.C.; Braun, J.E.; Kim, S.W. Mitochondrial chaperone DnaJA3 induces Drp1-dependent mitochondrial fragmentation. Int. J. Biochem. Cell Biol. 2012, 44, 1366-1376. [CrossRef] [PubMed]
-
(2012)
Int. J. Biochem. Cell Biol.
, vol.44
, pp. 1366-1376
-
-
Elwi, A.N.1
Lee, B.2
Meijndert, H.C.3
Braun, J.E.4
Kim, S.W.5
-
34
-
-
84901036269
-
MARCH5-mediated quality control on acetylated Mfn1 facilitates mitochondrial homeostasis and cell survival
-
CrossRef, PubMed
-
Park, Y.Y.; Nguyen, O.T.; Kang, H.; Cho, H. MARCH5-mediated quality control on acetylated Mfn1 facilitates mitochondrial homeostasis and cell survival. Cell Death Dis. 2014, 5, e1172. [CrossRef] [PubMed]
-
(2014)
Cell Death Dis.
, vol.5
-
-
Park, Y.Y.1
Nguyen, O.T.2
Kang, H.3
Cho, H.4
-
35
-
-
84964533976
-
Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy
-
CrossRef, PubMed
-
Chen, M.; Chen, Z.; Wang, Y.; Tan, Z.; Zhu, C.; Li, Y.; Han, Z.; Chen, L.; Gao, R.; Liu, L.; et al. Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy. Autophagy 2016, 12, 689-702. [CrossRef] [PubMed]
-
(2016)
Autophagy
, vol.12
, pp. 689-702
-
-
Chen, M.1
Chen, Z.2
Wang, Y.3
Tan, Z.4
Zhu, C.5
Li, Y.6
Han, Z.7
Chen, L.8
Gao, R.9
Liu, L.10
-
36
-
-
84960428273
-
Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling
-
CrossRef, PubMed
-
Otera, H.; Miyata, N.; Kuge, O.; Mihara, K. Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling. J. Cell Biol. 2016, 212, 531-544. [CrossRef] [PubMed]
-
(2016)
J. Cell Biol.
, vol.212
, pp. 531-544
-
-
Otera, H.1
Miyata, N.2
Kuge, O.3
Mihara, K.4
-
37
-
-
84930607266
-
The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage
-
CrossRef, PubMed
-
Varanita, T.; Soriano, M.E.; Romanello, V.; Zaglia, T.; Quintana-Cabrera, R.; Semenzato, M.; Menabo, R.; Costa, V.; Civiletto, G.; Pesce, P.; et al. The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage. Cell Metab. 2015, 21, 834-844. [CrossRef] [PubMed]
-
(2015)
Cell Metab.
, vol.21
, pp. 834-844
-
-
Varanita, T.1
Soriano, M.E.2
Romanello, V.3
Zaglia, T.4
Quintana-Cabrera, R.5
Semenzato, M.6
Menabo, R.7
Costa, V.8
Civiletto, G.9
Pesce, P.10
-
38
-
-
79955623510
-
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
-
CrossRef, PubMed
-
Gomes, L.C.; Di Benedetto, G.; Scorrano, L. During autophagy mitochondria elongate, are spared from degradation and sustain cell viability. Nat. Cell Biol. 2011, 13, 589-598. [CrossRef] [PubMed]
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 589-598
-
-
Gomes, L.C.1
Di Benedetto, G.2
Scorrano, L.3
-
39
-
-
49749118684
-
CaM kinase I α-induced phosphorylation of Drp1 regulates mitochondrial morphology
-
CrossRef, PubMed
-
Han, X.J.; Lu, Y.F.; Li, S.A.; Kaitsuka, T.; Sato, Y.; Tomizawa, K.; Nairn, A.C.; Takei, K.; Matsui, H.; Matsushita, M. CaM kinase I α-induced phosphorylation of Drp1 regulates mitochondrial morphology. J. Cell Biol. 2008, 182, 573-585. [CrossRef] [PubMed]
-
(2008)
J. Cell Biol.
, vol.182
, pp. 573-585
-
-
Han, X.J.1
Lu, Y.F.2
Li, S.A.3
Kaitsuka, T.4
Sato, Y.5
Tomizawa, K.6
Nairn, A.C.7
Takei, K.8
Matsui, H.9
Matsushita, M.10
-
40
-
-
81355133169
-
Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia
-
CrossRef, PubMed
-
Kim, H.; Scimia, M.C.; Wilkinson, D.; Trelles, R.D.; Wood, M.R.; Bowtell, D.; Dillin, A.; Mercola, M.; Ronai, Z.A. Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia. Mol. Cell 2011, 44, 532-544. [CrossRef] [PubMed]
-
(2011)
Mol. Cell
, vol.44
, pp. 532-544
-
-
Kim, H.1
Scimia, M.C.2
Wilkinson, D.3
Trelles, R.D.4
Wood, M.R.5
Bowtell, D.6
Dillin, A.7
Mercola, M.8
Ronai, Z.A.9
-
41
-
-
79955487757
-
Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1
-
CrossRef, PubMed
-
Merrill, R.A.; Dagda, R.K.; Dickey, A.S.; Cribbs, J.T.; Green, S.H.; Usachev, Y.M.; Strack, S. Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1. PLoS Biol. 2011, 9, e1000612. [CrossRef] [PubMed]
-
(2011)
PLoS Biol.
, vol.9
-
-
Merrill, R.A.1
Dagda, R.K.2
Dickey, A.S.3
Cribbs, J.T.4
Green, S.H.5
Usachev, Y.M.6
Strack, S.7
-
42
-
-
84862909353
-
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
-
CrossRef, PubMed
-
Wang, Z.; Jiang, H.; Chen, S.; Du, F.; Wang, X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 2012, 148, 228-243. [CrossRef] [PubMed]
-
(2012)
Cell
, vol.148
, pp. 228-243
-
-
Wang, Z.1
Jiang, H.2
Chen, S.3
Du, F.4
Wang, X.5
-
43
-
-
84893127504
-
Mitochondria: A kinase anchoring protein 1, a signaling platform for mitochondrial form and function
-
CrossRef, PubMed
-
Merrill, R.A.; Strack, S. Mitochondria: A kinase anchoring protein 1, a signaling platform for mitochondrial form and function. Int. J. Biochem. Cell Biol. 2014, 48, 92-96. [CrossRef] [PubMed]
-
(2014)
Int. J. Biochem. Cell Biol.
, vol.48
, pp. 92-96
-
-
Merrill, R.A.1
Strack, S.2
-
44
-
-
84880008164
-
Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules
-
CrossRef, PubMed
-
Strack, S.; Wilson, T.J.; Cribbs, J.T. Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules. J. Cell Biol. 2013, 201, 1037-1051. [CrossRef] [PubMed]
-
(2013)
J. Cell Biol.
, vol.201
, pp. 1037-1051
-
-
Strack, S.1
Wilson, T.J.2
Cribbs, J.T.3
-
45
-
-
84962920513
-
Early ERK1/2 activation promotes Drp1-dependent mitochondrial fission necessary for cell reprogramming
-
CrossRef, PubMed
-
Prieto, J.; Leon, M.; Ponsoda, X.; Sendra, R.; Bort, R.; Ferrer-Lorente, R.; Raya, A.; Lopez-Garcia, C.; Torres, J. Early ERK1/2 activation promotes Drp1-dependent mitochondrial fission necessary for cell reprogramming. Nat. Commun. 2016, 7, 11124. [CrossRef] [PubMed]
-
(2016)
Nat. Commun.
, vol.7
, pp. 11124
-
-
Prieto, J.1
Leon, M.2
Ponsoda, X.3
Sendra, R.4
Bort, R.5
Ferrer-Lorente, R.6
Raya, A.7
Lopez-Garcia, C.8
Torres, J.9
-
46
-
-
84955242874
-
Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction
-
CrossRef, PubMed
-
Li, J.; Wang, Y.; Wen, X.; Ma, X.N.; Chen,W.; Huang, F.; Kou, J.; Qi, L.W.; Liu, B.; Liu, K. Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction. J. Mol. Cell. Cardiol. 2015, 86, 62-74. [CrossRef] [PubMed]
-
(2015)
J. Mol. Cell. Cardiol.
, vol.86
, pp. 62-74
-
-
Li, J.1
Wang, Y.2
Wen, X.3
Ma, X.N.4
Chen, W.5
Huang, F.6
Kou, J.7
Qi, L.W.8
Liu, B.9
Liu, K.10
-
47
-
-
79959987510
-
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
-
CrossRef, PubMed
-
Rambold, A.S.; Kostelecky, B.; Elia, N.; Lippincott-Schwartz, J. Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation. Proc. Natl. Acad. Sci. USA 2011, 108, 10190-10195. [CrossRef] [PubMed]
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 10190-10195
-
-
Rambold, A.S.1
Kostelecky, B.2
Elia, N.3
Lippincott-Schwartz, J.4
-
48
-
-
85009884138
-
Dynamin-related protein 1 (Drp1) mediating mitophagy contributes to the pathophysiology of nervous system diseases and brain injury
-
CrossRef, PubMed
-
Wu, Q.; Luo, C.L.; Tao, L.Y. Dynamin-related protein 1 (Drp1) mediating mitophagy contributes to the pathophysiology of nervous system diseases and brain injury. Histol. Histopathol. 2016. [CrossRef] [PubMed]
-
(2016)
Histol. Histopathol
-
-
Wu, Q.1
Luo, C.L.2
Tao, L.Y.3
-
49
-
-
80155137546
-
PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics
-
CrossRef, PubMed
-
Dickey, A.S.; Strack, S. PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics. J. Neurosci. 2011, 31, 15716-15726. [CrossRef] [PubMed]
-
(2011)
J. Neurosci.
, vol.31
, pp. 15716-15726
-
-
Dickey, A.S.1
Strack, S.2
-
50
-
-
78751470559
-
Aberrant mitochondrial fission in neurons induced by protein kinase Cδ under oxidative stress conditions in vivo
-
CrossRef, PubMed
-
Qi, X.; Disatnik, M.H.; Shen, N.; Sobel, R.A.; Mochly-Rosen, D. Aberrant mitochondrial fission in neurons induced by protein kinase Cδ under oxidative stress conditions in vivo. Mol. Biol. Cell 2011, 22, 256-265. [CrossRef] [PubMed]
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 256-265
-
-
Qi, X.1
Disatnik, M.H.2
Shen, N.3
Sobel, R.A.4
Mochly-Rosen, D.5
-
51
-
-
84869856304
-
GSK3β-mediated Drp1 phosphorylation induced elongated mitochondrial morphology against oxidative stress
-
CrossRef, PubMed
-
Chou, C.H.; Lin, C.C.; Yang, M.C.; Wei, C.C.; Liao, H.D.; Lin, R.C.; Tu, W.Y.; Kao, T.C.; Hsu, C.M.; Cheng, J.T.; et al. GSK3β-mediated Drp1 phosphorylation induced elongated mitochondrial morphology against oxidative stress. PLoS ONE 2012, 7, e49112. [CrossRef] [PubMed]
-
(2012)
PLoS ONE
, vol.7
-
-
Chou, C.H.1
Lin, C.C.2
Yang, M.C.3
Wei, C.C.4
Liao, H.D.5
Lin, R.C.6
Tu, W.Y.7
Kao, T.C.8
Hsu, C.M.9
Cheng, J.T.10
-
52
-
-
84863023552
-
Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells
-
CrossRef, PubMed
-
Wang,W.;Wang, Y.; Long, J.;Wang, J.; Haudek, S.B.; Overbeek, P.; Chang, B.H.; Schumacker, P.T.; Danesh, F.R. Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. Cell Metab. 2012, 15, 186-200. [CrossRef] [PubMed]
-
(2012)
Cell Metab.
, vol.15
, pp. 186-200
-
-
Wang, W.1
Wang, Y.2
Long, J.3
Wang, J.4
Haudek, S.B.5
Overbeek, P.6
Chang, B.H.7
Schumacker, P.T.8
Danesh, F.R.9
-
53
-
-
85018445174
-
Mitochondrial morphology and cellular distribution are altered in SPG31 patients and are linked to Drp1 hyperphosphorylation
-
CrossRef, PubMed
-
Lavie, J.; Serrat, R.; Bellance, N.; Courtand, G.; Dupuy, J.W.; Tesson, C.; Coupry, I.; Brice, A.; Lacombe, D.; Durr, A.; et al. Mitochondrial morphology and cellular distribution are altered in SPG31 patients and are linked to Drp1 hyperphosphorylation. Hum. Mol. Genet. 2016. [CrossRef] [PubMed]
-
(2016)
Hum. Mol. Genet
-
-
Lavie, J.1
Serrat, R.2
Bellance, N.3
Courtand, G.4
Dupuy, J.W.5
Tesson, C.6
Coupry, I.7
Brice, A.8
Lacombe, D.9
Durr, A.10
-
54
-
-
84861640093
-
Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension
-
CrossRef, PubMed
-
Marsboom, G.; Toth, P.T.; Ryan, J.J.; Hong, Z.; Wu, X.; Fang, Y.H.; Thenappan, T.; Piao, L.; Zhang, H.J.; Pogoriler, J.; et al. Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. Circ. Res. 2012, 110, 1484-1497. [CrossRef] [PubMed]
-
(2012)
Circ. Res.
, vol.110
, pp. 1484-1497
-
-
Marsboom, G.1
Toth, P.T.2
Ryan, J.J.3
Hong, Z.4
Wu, X.5
Fang, Y.H.6
Thenappan, T.7
Piao, L.8
Zhang, H.J.9
Pogoriler, J.10
-
55
-
-
84941600324
-
Regulation of mitochondrial morphology by positive feedback interaction between PKCδ and Drp1 in vascular smooth muscle cell
-
CrossRef, PubMed
-
Lim, S.; Lee, S.Y.; Seo, H.H.; Ham, O.; Lee, C.; Park, J.H.; Lee, J.; Seung, M.; Yun, I.; Han, S.M.; et al. Regulation of mitochondrial morphology by positive feedback interaction between PKCδ and Drp1 in vascular smooth muscle cell. J. Cell. Biochem. 2015, 116, 648-660. [CrossRef] [PubMed]
-
(2015)
J. Cell. Biochem.
, vol.116
, pp. 648-660
-
-
Lim, S.1
Lee, S.Y.2
Seo, H.H.3
Ham, O.4
Lee, C.5
Park, J.H.6
Lee, J.7
Seung, M.8
Yun, I.9
Han, S.M.10
-
56
-
-
79961021186
-
Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus
-
CrossRef, PubMed
-
Shenouda, S.M.; Widlansky, M.E.; Chen, K.; Xu, G.; Holbrook, M.; Tabit, C.E.; Hamburg, N.M.; Frame, A.A.; Caiano, T.L.; Kluge, M.A.; et al. Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus. Circulation 2011, 124, 444-453. [CrossRef] [PubMed]
-
(2011)
Circulation
, vol.124
, pp. 444-453
-
-
Shenouda, S.M.1
Widlansky, M.E.2
Chen, K.3
Xu, G.4
Holbrook, M.5
Tabit, C.E.6
Hamburg, N.M.7
Frame, A.A.8
Caiano, T.L.9
Kluge, M.A.10
-
57
-
-
84881126185
-
HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE
-
CrossRef, PubMed
-
Caza, T.N.; Fernandez, D.R.; Talaber, G.; Oaks, Z.; Haas, M.; Madaio, M.P.; Lai, Z.W.; Miklossy, G.; Singh, R.R.; Chudakov, D.M.; et al. HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE. Ann. Rheum Dis. 2014, 73, 1888-1897. [CrossRef] [PubMed]
-
(2014)
Ann. Rheum Dis.
, vol.73
, pp. 1888-1897
-
-
Caza, T.N.1
Fernandez, D.R.2
Talaber, G.3
Oaks, Z.4
Haas, M.5
Madaio, M.P.6
Lai, Z.W.7
Miklossy, G.8
Singh, R.R.9
Chudakov, D.M.10
-
58
-
-
84957922351
-
Disturbed mitochondrial and peroxisomal dynamics due to loss of MFF causes Leigh-like encephalopathy, optic atrophy and peripheral neuropathy
-
CrossRef, PubMed
-
Koch, J.; Feichtinger, R.G.; Freisinger, P.; Pies, M.; Schrodl, F.; Iuso, A.; Sperl, W.; Mayr, J.A.; Prokisch, H.; Haack, T.B. Disturbed mitochondrial and peroxisomal dynamics due to loss of MFF causes Leigh-like encephalopathy, optic atrophy and peripheral neuropathy. J. Med. Genet. 2016, 53, 270-278. [CrossRef] [PubMed]
-
(2016)
J. Med. Genet.
, vol.53
, pp. 270-278
-
-
Koch, J.1
Feichtinger, R.G.2
Freisinger, P.3
Pies, M.4
Schrodl, F.5
Iuso, A.6
Sperl, W.7
Mayr, J.A.8
Prokisch, H.9
Haack, T.B.10
-
59
-
-
84890096545
-
Inhibition of mitochondrial fragmentation diminishes Huntington’s disease-associated neurodegeneration
-
CrossRef, PubMed
-
Guo, X.; Disatnik, M.H.; Monbureau, M.; Shamloo, M.; Mochly-Rosen, D.; Qi, X. Inhibition of mitochondrial fragmentation diminishes Huntington’s disease-associated neurodegeneration. J. Clin. Investig. 2013, 123, 5371-5388. [CrossRef] [PubMed]
-
(2013)
J. Clin. Investig.
, vol.123
, pp. 5371-5388
-
-
Guo, X.1
Disatnik, M.H.2
Monbureau, M.3
Shamloo, M.4
Mochly-Rosen, D.5
Qi, X.6
-
60
-
-
85014325731
-
A reduction in Drp1-mediated fission compromises mitochondrial health in autosomal recessive spastic ataxia of Charlevoix Saguenay
-
CrossRef, PubMed
-
Bradshaw, T.Y.; Romano, L.E.; Duncan, E.J.; Nethisinghe, S.; Abeti, R.; Michael, G.J.; Giunti, P.; Vermeer, S.; Chapple, J.P. A reduction in Drp1-mediated fission compromises mitochondrial health in autosomal recessive spastic ataxia of Charlevoix Saguenay. Hum. Mol. Genet. 2016, 25, 3232-3244. [CrossRef] [PubMed]
-
(2016)
Hum. Mol. Genet.
, vol.25
, pp. 3232-3244
-
-
Bradshaw, T.Y.1
Romano, L.E.2
Duncan, E.J.3
Nethisinghe, S.4
Abeti, R.5
Michael, G.J.6
Giunti, P.7
Vermeer, S.8
Chapple, J.P.9
-
61
-
-
34447274052
-
Small molecule inhibition of the Bcl-X(L)-BH3 protein-protein interaction: Proof-of-concept of an in vivo chemopotentiator ABT-737
-
CrossRef, PubMed
-
Stauffer, S.R. Small molecule inhibition of the Bcl-X(L)-BH3 protein-protein interaction: Proof-of-concept of an in vivo chemopotentiator ABT-737. Curr. Top. Med. Chem. 2007, 7, 961-965. [CrossRef] [PubMed]
-
(2007)
Curr. Top. Med. Chem.
, vol.7
, pp. 961-965
-
-
Stauffer, S.R.1
-
62
-
-
84937764173
-
Roles of PTEN-induced putative kinase 1 and dynamin-related protein 1 in transient global ischemia-induced hippocampal neuronal injury
-
CrossRef, PubMed
-
Chen, S.D.; Lin, T.K.; Yang, D.I.; Lee, S.Y.; Shaw, F.Z.; Liou, C.W.; Chuang, Y.C. Roles of PTEN-induced putative kinase 1 and dynamin-related protein 1 in transient global ischemia-induced hippocampal neuronal injury. Biochem. Biophys. Res. Commun. 2015, 460, 397-403. [CrossRef] [PubMed]
-
(2015)
Biochem. Biophys. Res. Commun.
, vol.460
, pp. 397-403
-
-
Chen, S.D.1
Lin, T.K.2
Yang, D.I.3
Lee, S.Y.4
Shaw, F.Z.5
Liou, C.W.6
Chuang, Y.C.7
-
63
-
-
84961282095
-
Postnatal microcephaly and pain insensitivity due to a de novo heterozygous DNM1L mutation causing impaired mitochondrial fission and function
-
CrossRef, PubMed
-
Sheffer, R.; Douiev, L.; Edvardson, S.; Shaag, A.; Tamimi, K.; Soiferman, D.; Meiner, V.; Saada, A. Postnatal microcephaly and pain insensitivity due to a de novo heterozygous DNM1L mutation causing impaired mitochondrial fission and function. Am. J. Med. Genet. A 2016, 170, 1603-1607. [CrossRef] [PubMed]
-
(2016)
Am. J. Med. Genet. A
, vol.170
, pp. 1603-1607
-
-
Sheffer, R.1
Douiev, L.2
Edvardson, S.3
Shaag, A.4
Tamimi, K.5
Soiferman, D.6
Meiner, V.7
Saada, A.8
-
64
-
-
84880940047
-
S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington’s disease
-
CrossRef, PubMed
-
Haun, F.; Nakamura, T.; Shiu, A.D.; Cho, D.H.; Tsunemi, T.; Holland, E.A.; La Spada, A.R.; Lipton, S.A. S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington’s disease. Antioxid. Redox Signal. 2013, 19, 1173-1184. [CrossRef] [PubMed]
-
(2013)
Antioxid. Redox Signal.
, vol.19
, pp. 1173-1184
-
-
Haun, F.1
Nakamura, T.2
Shiu, A.D.3
Cho, D.H.4
Tsunemi, T.5
Holland, E.A.6
La Spada, A.R.7
Lipton, S.A.8
-
65
-
-
84943802980
-
Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics
-
CrossRef, PubMed
-
Xiao, L.; Xian, H.; Lee, K.Y.; Xiao, B.; Wang, H.; Yu, F.; Shen, H.M.; Liou, Y.C. Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics. J. Biol. Chem. 2015, 290, 24961-24974. [CrossRef] [PubMed]
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 24961-24974
-
-
Xiao, L.1
Xian, H.2
Lee, K.Y.3
Xiao, B.4
Wang, H.5
Yu, F.6
Shen, H.M.7
Liou, Y.C.8
-
66
-
-
84930581497
-
Perspectives on biologically active camptothecin derivatives
-
CrossRef, PubMed
-
Liu, Y.Q.; Li,W.Q.; Morris-Natschke, S.L.; Qian, K.; Yang, L.; Zhu, G.X.;Wu, X.B.; Chen, A.L.; Zhang, S.Y.; Nan, X.; et al. Perspectives on biologically active camptothecin derivatives. Med. Res. Rev. 2015, 35, 753-789. [CrossRef] [PubMed]
-
(2015)
Med. Res. Rev.
, vol.35
, pp. 753-789
-
-
Liu, Y.Q.1
Li, W.Q.2
Morris-Natschke, S.L.3
Qian, K.4
Yang, L.5
Zhu, G.X.6
Wu, X.B.7
Chen, A.L.8
Zhang, S.Y.9
Nan, X.10
-
67
-
-
84958568728
-
Multiple faces of dynamin-related protein 1 and its role in Alzheimer’s disease pathogenesis
-
CrossRef, PubMed
-
Kandimalla, R.; Reddy, P.H. Multiple faces of dynamin-related protein 1 and its role in Alzheimer’s disease pathogenesis. Biochim. Biophys. Acta 2016, 1862, 814-828. [CrossRef] [PubMed]
-
(2016)
Biochim. Biophys. Acta
, vol.1862
, pp. 814-828
-
-
Kandimalla, R.1
Reddy, P.H.2
-
68
-
-
84941799317
-
MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death
-
CrossRef, PubMed
-
Prudent, J.; Zunino, R.; Sugiura, A.; Mattie, S.; Shore, G.C.; McBride, H.M. MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death. Mol. Cell 2015, 59, 941-955. [CrossRef] [PubMed]
-
(2015)
Mol. Cell
, vol.59
, pp. 941-955
-
-
Prudent, J.1
Zunino, R.2
Sugiura, A.3
Mattie, S.4
Shore, G.C.5
McBride, H.M.6
-
69
-
-
79954569219
-
Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability
-
CrossRef, PubMed
-
Horn, S.R.; Thomenius, M.J.; Johnson, E.S.; Freel, C.D.; Wu, J.Q.; Coloff, J.L.; Yang, C.S.; Tang, W.; An, J.; Ilkayeva, O.R.; et al. Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability. Mol. Biol. Cell 2011, 22, 1207-1216. [CrossRef] [PubMed]
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 1207-1216
-
-
Horn, S.R.1
Thomenius, M.J.2
Johnson, E.S.3
Freel, C.D.4
Wu, J.Q.5
Coloff, J.L.6
Yang, C.S.7
Tang, W.8
An, J.9
Ilkayeva, O.R.10
-
70
-
-
67650076601
-
MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission
-
CrossRef, PubMed
-
Braschi, E.; Zunino, R.; McBride, H.M. MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission. EMBO Rep. 2009, 10, 748-754. [CrossRef] [PubMed]
-
(2009)
EMBO Rep.
, vol.10
, pp. 748-754
-
-
Braschi, E.1
Zunino, R.2
McBride, H.M.3
-
71
-
-
84916594758
-
SENP5, a SUMO isopeptidase, induces apoptosis and cardiomyopathy
-
CrossRef, PubMed
-
Kim, E.Y.; Zhang, Y.; Beketaev, I.; Segura, A.M.; Yu, W.; Xi, Y.; Chang, J.; Wang, J. SENP5, a SUMO isopeptidase, induces apoptosis and cardiomyopathy. J. Mol. Cell. Cardiol. 2015, 78, 154-164. [CrossRef] [PubMed]
-
(2015)
J. Mol. Cell. Cardiol.
, vol.78
, pp. 154-164
-
-
Kim, E.Y.1
Zhang, Y.2
Beketaev, I.3
Segura, A.M.4
Yu, W.5
Xi, Y.6
Chang, J.7
Wang, J.8
-
72
-
-
67650534951
-
Translocation of SenP5 from the nucleoli to the mitochondria modulates Drp1-dependent fission during mitosis
-
CrossRef, PubMed
-
Zunino, R.; Braschi, E.; Xu, L.; McBride, H.M. Translocation of SenP5 from the nucleoli to the mitochondria modulates Drp1-dependent fission during mitosis. J. Biol. Chem. 2009, 284, 17783-17795. [CrossRef] [PubMed]
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 17783-17795
-
-
Zunino, R.1
Braschi, E.2
Xu, L.3
McBride, H.M.4
-
73
-
-
84878597289
-
SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia
-
CrossRef, PubMed
-
Guo, C.; Hildick, K.L.; Luo, J.; Dearden, L.;Wilkinson, K.A.; Henley, J.M. SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia. EMBO J. 2013, 32, 1514-1528. [CrossRef] [PubMed]
-
(2013)
EMBO J.
, vol.32
, pp. 1514-1528
-
-
Guo, C.1
Hildick, K.L.2
Luo, J.3
Dearden, L.4
Wilkinson, K.A.5
Henley, J.M.6
-
74
-
-
84865457924
-
Modulation of dynamin-related protein 1 (Drp1) function by increased O-linked-β-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes
-
CrossRef, PubMed
-
Gawlowski, T.; Suarez, J.; Scott, B.; Torres-Gonzalez, M.;Wang, H.; Schwappacher, R.; Han, X.; Yates, J.R., 3rd; Hoshijima, M.; Dillmann, W. Modulation of dynamin-related protein 1 (Drp1) function by increased O-linked-β-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes. J. Biol. Chem. 2012, 287, 30024-30034. [CrossRef] [PubMed]
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 30024-30034
-
-
Gawlowski, T.1
Suarez, J.2
Scott, B.3
Torres-Gonzalez, M.4
Wang, H.5
Schwappacher, R.6
Han, X.7
Yates 3rd, J.R.8
Hoshijima, M.9
Dillmann, W.10
-
75
-
-
77955431941
-
S-Nitrosylation of Drp1 does not affect enzymatic activity and is not specific to Alzheimer’s disease
-
PubMed
-
Bossy, B.; Petrilli, A.; Klinglmayr, E.; Chen, J.; Lutz-Meindl, U.; Knott, A.B.; Masliah, E.; Schwarzenbacher, R.; Bossy-Wetzel, E. S-Nitrosylation of Drp1 does not affect enzymatic activity and is not specific to Alzheimer’s disease. J. Alzheimers Dis. 2010, 20 (Suppl. S2), S513-S526. [PubMed]
-
(2010)
J. Alzheimers Dis
, vol.20
, pp. S513-S526
-
-
Bossy, B.1
Petrilli, A.2
Klinglmayr, E.3
Chen, J.4
Lutz-Meindl, U.5
Knott, A.B.6
Masliah, E.7
Schwarzenbacher, R.8
Bossy-Wetzel, E.9
-
76
-
-
84908326342
-
Mitochondrial fission factor Drp1 maintains oocyte quality via dynamic rearrangement of multiple organelles
-
CrossRef, PubMed
-
Udagawa, O.; Ishihara, T.; Maeda, M.; Matsunaga, Y.; Tsukamoto, S.; Kawano, N.; Miyado, K.; Shitara, H.; Yokota, S.; Nomura, M.; et al. Mitochondrial fission factor Drp1 maintains oocyte quality via dynamic rearrangement of multiple organelles. Curr. Biol. 2014, 24, 2451-2458. [CrossRef] [PubMed]
-
(2014)
Curr. Biol.
, vol.24
, pp. 2451-2458
-
-
Udagawa, O.1
Ishihara, T.2
Maeda, M.3
Matsunaga, Y.4
Tsukamoto, S.5
Kawano, N.6
Miyado, K.7
Shitara, H.8
Yokota, S.9
Nomura, M.10
-
77
-
-
84938632163
-
Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice
-
CrossRef, PubMed
-
Leduc-Gaudet, J.P.; Picard, M.; St-Jean Pelletier, F.; Sgarioto, N.; Auger, M.J.; Vallee, J.; Robitaille, R.; St-Pierre, D.H.; Gouspillou, G. Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice. Oncotarget 2015, 6, 17923-17937. [CrossRef] [PubMed]
-
(2015)
Oncotarget
, vol.6
, pp. 17923-17937
-
-
Leduc-Gaudet, J.P.1
Picard, M.2
St-Jean Pelletier, F.3
Sgarioto, N.4
Auger, M.J.5
Vallee, J.6
Robitaille, R.7
St-Pierre, D.H.8
Gouspillou, G.9
-
78
-
-
77954169092
-
A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy
-
CrossRef, PubMed
-
Ashrafian, H.; Docherty, L.; Leo, V.; Towlson, C.; Neilan, M.; Steeples, V.; Lygate, C.A.; Hough, T.; Townsend, S.; Williams, D.; et al. A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy. PLoS Genet. 2010, 6, e1001000. [CrossRef] [PubMed]
-
(2010)
PLoS Genet.
, vol.6
-
-
Ashrafian, H.1
Docherty, L.2
Leo, V.3
Towlson, C.4
Neilan, M.5
Steeples, V.6
Lygate, C.A.7
Hough, T.8
Townsend, S.9
Williams, D.10
-
79
-
-
84921985434
-
Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stress
-
CrossRef, PubMed
-
Ikeda, Y.; Shirakabe, A.; Maejima, Y.; Zhai, P.; Sciarretta, S.; Toli, J.; Nomura, M.; Mihara, K.; Egashira, K.; Ohishi, M.; et al. Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stress. Circ. Res. 2015, 116, 264-278. [CrossRef] [PubMed]
-
(2015)
Circ. Res.
, vol.116
, pp. 264-278
-
-
Ikeda, Y.1
Shirakabe, A.2
Maejima, Y.3
Zhai, P.4
Sciarretta, S.5
Toli, J.6
Nomura, M.7
Mihara, K.8
Egashira, K.9
Ohishi, M.10
-
80
-
-
84987623640
-
Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson’s disease model induced by MPTP
-
CrossRef, PubMed
-
Filichia, E.; Hoffer, B.; Qi, X.; Luo, Y. Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson’s disease model induced by MPTP. Sci. Rep. 2016, 6, 32656. [CrossRef] [PubMed]
-
(2016)
Sci. Rep.
, vol.6
, pp. 32656
-
-
Filichia, E.1
Hoffer, B.2
Qi, X.3
Luo, Y.4
-
81
-
-
70349944660
-
The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
-
CrossRef, PubMed
-
Wakabayashi, J.; Zhang, Z.;Wakabayashi, N.; Tamura, Y.; Fukaya, M.; Kensler, T.W.; Iijima, M.; Sesaki, H. The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice. J. Cell Biol. 2009, 186, 805-816. [CrossRef] [PubMed]
-
(2009)
J. Cell Biol.
, vol.186
, pp. 805-816
-
-
Wakabayashi, J.1
Zhang, Z.2
Wakabayashi, N.3
Tamura, Y.4
Fukaya, M.5
Kensler, T.W.6
Iijima, M.7
Sesaki, H.8
-
82
-
-
84927633805
-
Muscle-specific Drp1 overexpression impairs skeletal muscle growth via translational attenuation
-
CrossRef, PubMed
-
Touvier, T.; de Palma, C.; Rigamonti, E.; Scagliola, A.; Incerti, E.; Mazelin, L.; Thomas, J.L.; D’Antonio, M.; Politi, L.; Schaeffer, L.; et al. Muscle-specific Drp1 overexpression impairs skeletal muscle growth via translational attenuation. Cell Death Dis. 2015, 6, e1663. [CrossRef] [PubMed]
-
(2015)
Cell Death Dis.
, vol.6
-
-
Touvier, T.1
De Palma, C.2
Rigamonti, E.3
Scagliola, A.4
Incerti, E.5
Mazelin, L.6
Thomas, J.L.7
D’Antonio, M.8
Politi, L.9
Schaeffer, L.10
-
83
-
-
84913543630
-
Drp1 is dispensable for mitochondria biogenesis in induction to pluripotency but required for differentiation of embryonic stem cells
-
CrossRef, PubMed
-
Wang, L.; Ye, X.; Zhao, Q.; Zhou, Z.; Dan, J.; Zhu, Y.; Chen, Q.; Liu, L. Drp1 is dispensable for mitochondria biogenesis in induction to pluripotency but required for differentiation of embryonic stem cells. Stem Cells Dev. 2014, 23, 2422-2434. [CrossRef] [PubMed]
-
(2014)
Stem Cells Dev.
, vol.23
, pp. 2422-2434
-
-
Wang, L.1
Ye, X.2
Zhao, Q.3
Zhou, Z.4
Dan, J.5
Zhu, Y.6
Chen, Q.7
Liu, L.8
-
84
-
-
84949774181
-
A new mitochondrial pool of cyclin E, regulated by Drp1, is linked to cell-density-dependent cell proliferation
-
CrossRef, PubMed
-
Parker, D.J.; Iyer, A.; Shah, S.; Moran, A.; Hjelmeland, A.B.; Basu, M.K.; Liu, R.; Mitra, K. A new mitochondrial pool of cyclin E, regulated by Drp1, is linked to cell-density-dependent cell proliferation. J. Cell Sci. 2015, 128, 4171-4182. [CrossRef] [PubMed]
-
(2015)
J. Cell Sci.
, vol.128
, pp. 4171-4182
-
-
Parker, D.J.1
Iyer, A.2
Shah, S.3
Moran, A.4
Hjelmeland, A.B.5
Basu, M.K.6
Liu, R.7
Mitra, K.8
-
85
-
-
77957829340
-
Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation
-
CrossRef, PubMed
-
De Palma, C.; Falcone, S.; Pisoni, S.; Cipolat, S.; Panzeri, C.; Pambianco, S.; Pisconti, A.; Allevi, R.; Bassi, M.T.; Cossu, G.; et al. Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation. Cell Death Differ. 2010, 17, 1684-1696. [CrossRef] [PubMed]
-
(2010)
Cell Death Differ.
, vol.17
, pp. 1684-1696
-
-
De Palma, C.1
Falcone, S.2
Pisoni, S.3
Cipolat, S.4
Panzeri, C.5
Pambianco, S.6
Pisconti, A.7
Allevi, R.8
Bassi, M.T.9
Cossu, G.10
-
86
-
-
84874779519
-
Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus
-
CrossRef, PubMed
-
Hong, Z.; Kutty, S.; Toth, P.T.; Marsboom, G.; Hammel, J.M.; Chamberlain, C.; Ryan, J.J.; Zhang, H.J.; Sharp, W.W.; Morrow, E.; et al. Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus. Circ. Res. 2013, 112, 802-815. [CrossRef] [PubMed]
-
(2013)
Circ. Res.
, vol.112
, pp. 802-815
-
-
Hong, Z.1
Kutty, S.2
Toth, P.T.3
Marsboom, G.4
Hammel, J.M.5
Chamberlain, C.6
Ryan, J.J.7
Zhang, H.J.8
Sharp, W.W.9
Morrow, E.10
-
87
-
-
67649786569
-
Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons
-
CrossRef, PubMed
-
Uo, T.; Dworzak, J.; Kinoshita, C.; Inman, D.M.; Kinoshita, Y.; Horner, P.J.; Morrison, R.S. Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons. Exp. Neurol. 2009, 218, 274-285. [CrossRef] [PubMed]
-
(2009)
Exp. Neurol.
, vol.218
, pp. 274-285
-
-
Uo, T.1
Dworzak, J.2
Kinoshita, C.3
Inman, D.M.4
Kinoshita, Y.5
Horner, P.J.6
Morrison, R.S.7
-
88
-
-
77955908881
-
A novel Gfer-Drp1 link in preserving mitochondrial dynamics and function in pluripotent stem cells
-
CrossRef, PubMed
-
Todd, L.R.; Gomathinayagam, R.; Sankar, U. A novel Gfer-Drp1 link in preserving mitochondrial dynamics and function in pluripotent stem cells. Autophagy 2010, 6, 821-822. [CrossRef] [PubMed]
-
(2010)
Autophagy
, vol.6
, pp. 821-822
-
-
Todd, L.R.1
Gomathinayagam, R.2
Sankar, U.3
-
89
-
-
77950630969
-
Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells
-
CrossRef, PubMed
-
Todd, L.R.; Damin, M.N.; Gomathinayagam, R.; Horn, S.R.; Means, A.R.; Sankar, U. Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells. Mol. Biol. Cell 2010, 21, 1225-1236. [CrossRef] [PubMed]
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 1225-1236
-
-
Todd, L.R.1
Damin, M.N.2
Gomathinayagam, R.3
Horn, S.R.4
Means, A.R.5
Sankar, U.6
-
90
-
-
84899887277
-
Drp1 in ischemic neuronal death: An unusual suspect
-
CrossRef, PubMed
-
Pradeep, H.; Sharma, B.; Rajanikant, G.K. Drp1 in ischemic neuronal death: An unusual suspect. Curr. Med. Chem. 2014, 21, 2183-2189. [CrossRef] [PubMed]
-
(2014)
Curr. Med. Chem.
, vol.21
, pp. 2183-2189
-
-
Pradeep, H.1
Sharma, B.2
Rajanikant, G.K.3
-
91
-
-
79551600416
-
Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction
-
CrossRef, PubMed
-
Iwasawa, R.; Mahul-Mellier, A.L.; Datler, C.; Pazarentzos, E.; Grimm, S. Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction. EMBO J. 2011, 30, 556-568. [CrossRef] [PubMed]
-
(2011)
EMBO J.
, vol.30
, pp. 556-568
-
-
Iwasawa, R.1
Mahul-Mellier, A.L.2
Datler, C.3
Pazarentzos, E.4
Grimm, S.5
-
92
-
-
84911496555
-
Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death
-
CrossRef, PubMed
-
Martorell-Riera, A.; Segarra-Mondejar, M.; Munoz, J.P.; Ginet, V.; Olloquequi, J.; Perez-Clausell, J.; Palacin, M.; Reina, M.; Puyal, J.; Zorzano, A.; et al. Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death. EMBO J. 2014, 33, 2388-2407. [CrossRef] [PubMed]
-
(2014)
EMBO J.
, vol.33
, pp. 2388-2407
-
-
Martorell-Riera, A.1
Segarra-Mondejar, M.2
Munoz, J.P.3
Ginet, V.4
Olloquequi, J.5
Perez-Clausell, J.6
Palacin, M.7
Reina, M.8
Puyal, J.9
Zorzano, A.10
-
93
-
-
84880384547
-
Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome C
-
CrossRef, PubMed
-
Ban-Ishihara, R.; Ishihara, T.; Sasaki, N.; Mihara, K.; Ishihara, N. Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome C. Proc. Natl. Acad. Sci. USA 2013, 110, 11863-11868. [CrossRef] [PubMed]
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 11863-11868
-
-
Ban-Ishihara, R.1
Ishihara, T.2
Sasaki, N.3
Mihara, K.4
Ishihara, N.5
-
94
-
-
18444400187
-
Endoplasmic reticulum BIK initiates Drp1-regulated remodelling of mitochondrial cristae during apoptosis
-
CrossRef, PubMed
-
Germain, M.; Mathai, J.P.; McBride, H.M.; Shore, G.C. Endoplasmic reticulum BIK initiates Drp1-regulated remodelling of mitochondrial cristae during apoptosis. EMBO J. 2005, 24, 1546-1556. [CrossRef] [PubMed]
-
(2005)
EMBO J.
, vol.24
, pp. 1546-1556
-
-
Germain, M.1
Mathai, J.P.2
McBride, H.M.3
Shore, G.C.4
-
95
-
-
34848840991
-
Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death
-
CrossRef, PubMed
-
Cribbs, J.T.; Strack, S. Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death. EMBO Rep. 2007, 8, 939-944. [CrossRef] [PubMed]
-
(2007)
EMBO Rep.
, vol.8
, pp. 939-944
-
-
Cribbs, J.T.1
Strack, S.2
-
96
-
-
84905119913
-
Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells
-
CrossRef, PubMed
-
Qian, W.; Wang, J.; Roginskaya, V.; McDermott, L.A.; Edwards, R.P.; Stolz, D.B.; Llambi, F.; Green, D.R.; van Houten, B. Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells. Oncotarget 2014, 5, 4180-4194. [CrossRef] [PubMed]
-
(2014)
Oncotarget
, vol.5
, pp. 4180-4194
-
-
Qian, W.1
Wang, J.2
Roginskaya, V.3
McDermott, L.A.4
Edwards, R.P.5
Stolz, D.B.6
Llambi, F.7
Green, D.R.8
Van Houten, B.9
-
97
-
-
84885675007
-
Inhibition of Drp1-dependent mitochondrial division impairs myogenic differentiation
-
CrossRef, PubMed
-
Kim, B.; Kim, J.S.; Yoon, Y.; Santiago, M.C.; Brown, M.D.; Park, J.Y. Inhibition of Drp1-dependent mitochondrial division impairs myogenic differentiation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2013, 305, R927-R938. [CrossRef] [PubMed]
-
(2013)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.305
, pp. R927-R938
-
-
Kim, B.1
Kim, J.S.2
Yoon, Y.3
Santiago, M.C.4
Brown, M.D.5
Park, J.Y.6
-
98
-
-
78649679754
-
Bax is essential for Drp1-mediated mitochondrial fission but not for mitochondrial outer membrane permeabilization caused by photodynamic therapy
-
CrossRef, PubMed
-
Wu, S.; Zhou, F.; Zhang, Z.; Xing, D. Bax is essential for Drp1-mediated mitochondrial fission but not for mitochondrial outer membrane permeabilization caused by photodynamic therapy. J. Cell. Physiol. 2011, 226, 530-541. [CrossRef] [PubMed]
-
(2011)
J. Cell. Physiol.
, vol.226
, pp. 530-541
-
-
Wu, S.1
Zhou, F.2
Zhang, Z.3
Xing, D.4
-
99
-
-
79952172319
-
Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis
-
CrossRef, PubMed
-
Brooks, C.; Cho, S.G.;Wang, C.Y.; Yang, T.; Dong, Z. Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis. Am. J. Physiol. Cell Physiol. 2011, 300, C447-C455. [CrossRef] [PubMed]
-
(2011)
Am. J. Physiol. Cell Physiol.
, vol.300
, pp. C447-C455
-
-
Brooks, C.1
Cho, S.G.2
Wang, C.Y.3
Yang, T.4
Dong, Z.5
-
100
-
-
84897372946
-
Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes
-
CrossRef, PubMed
-
Clerc, P.; Ge, S.X.; Hwang, H.; Waddell, J.; Roelofs, B.A.; Karbowski, M.; Sesaki, H.; Polster, B.M. Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes. Br. J. Pharmacol. 2014, 171, 1988-1999. [CrossRef] [PubMed]
-
(2014)
Br. J. Pharmacol.
, vol.171
, pp. 1988-1999
-
-
Clerc, P.1
Ge, S.X.2
Hwang, H.3
Waddell, J.4
Roelofs, B.A.5
Karbowski, M.6
Sesaki, H.7
Polster, B.M.8
-
101
-
-
84940789905
-
Astaxanthin prevents pulmonary fibrosis by promoting myofibroblast apoptosis dependent on Drp1-mediated mitochondrial fission
-
CrossRef, PubMed
-
Zhang, J.; Xu, P.; Wang, Y.; Wang, M.; Li, H.; Lin, S.; Mao, C.; Wang, B.; Song, X.; Lv, C. Astaxanthin prevents pulmonary fibrosis by promoting myofibroblast apoptosis dependent on Drp1-mediated mitochondrial fission. J. Cell. Mol. Med. 2015, 19, 2215-2231. [CrossRef] [PubMed]
-
(2015)
J. Cell. Mol. Med.
, vol.19
, pp. 2215-2231
-
-
Zhang, J.1
Xu, P.2
Wang, Y.3
Wang, M.4
Li, H.5
Lin, S.6
Mao, C.7
Wang, B.8
Song, X.9
Lv, C.10
-
102
-
-
84870997845
-
Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating Drp1 translocation
-
CrossRef, PubMed
-
Lin, H.Y.; Lai, R.H.; Lin, S.T.; Lin, R.C.; Wang, M.J.; Lin, C.C.; Lee, H.C.; Wang, F.F.; Chen, J.Y. Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating Drp1 translocation. Cell Death Differ. 2013, 20, 139-153. [CrossRef] [PubMed]
-
(2013)
Cell Death Differ.
, vol.20
, pp. 139-153
-
-
Lin, H.Y.1
Lai, R.H.2
Lin, S.T.3
Lin, R.C.4
Wang, M.J.5
Lin, C.C.6
Lee, H.C.7
Wang, F.F.8
Chen, J.Y.9
-
103
-
-
84946046423
-
The Drosophila retinoblastoma protein, Rbf1, induces a Debcl- and Drp1-dependent mitochondrial apoptosis
-
CrossRef, PubMed
-
Clavier, A.; Ruby, V.; Rincheval-Arnold, A.; Mignotte, B.; Guenal, I. The Drosophila retinoblastoma protein, Rbf1, induces a Debcl- and Drp1-dependent mitochondrial apoptosis. J. Cell Sci. 2015, 128, 3239-3249. [CrossRef] [PubMed]
-
(2015)
J. Cell Sci.
, vol.128
, pp. 3239-3249
-
-
Clavier, A.1
Ruby, V.2
Rincheval-Arnold, A.3
Mignotte, B.4
Guenal, I.5
-
104
-
-
84919869519
-
B-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting
-
CrossRef, PubMed
-
Su, Y.C.; Chiu, H.W.; Hung, J.C.; Hong, J.R. B-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting. Apoptosis 2014, 19, 1457-1470. [CrossRef] [PubMed]
-
(2014)
Apoptosis
, vol.19
, pp. 1457-1470
-
-
Su, Y.C.1
Chiu, H.W.2
Hung, J.C.3
Hong, J.R.4
-
105
-
-
84860431569
-
Endoplasmic reticulum-specific BH3-only protein BNIP1 induces mitochondrial fragmentation in a Bcl-2- and Drp1-dependent manner
-
CrossRef, PubMed
-
Ryu, S.W.; Choi, K.; Yoon, J.; Kim, S.; Choi, C. Endoplasmic reticulum-specific BH3-only protein BNIP1 induces mitochondrial fragmentation in a Bcl-2- and Drp1-dependent manner. J. Cell. Physiol. 2012, 227, 3027-3035. [CrossRef] [PubMed]
-
(2012)
J. Cell. Physiol.
, vol.227
, pp. 3027-3035
-
-
Ryu, S.W.1
Choi, K.2
Yoon, J.3
Kim, S.4
Choi, C.5
-
106
-
-
84905388716
-
Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage
-
CrossRef, PubMed
-
Zuo, W.; Zhang, S.; Xia, C.Y.; Guo, X.F.; He, W.B.; Chen, N.H. Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage. Neuropharmacology 2014, 86, 103-115. [CrossRef] [PubMed]
-
(2014)
Neuropharmacology
, vol.86
, pp. 103-115
-
-
Zuo, W.1
Zhang, S.2
Xia, C.Y.3
Guo, X.F.4
He, W.B.5
Chen, N.H.6
-
107
-
-
84902252468
-
Drp1 loss-of-function reduces cardiomyocyte oxygen dependence protecting the heart from ischemia-reperfusion injury
-
CrossRef, PubMed
-
Zepeda, R.; Kuzmicic, J.; Parra, V.; Troncoso, R.; Pennanen, C.; Riquelme, J.A.; Pedrozo, Z.; Chiong, M.; Sanchez, G.; Lavandero, S. Drp1 loss-of-function reduces cardiomyocyte oxygen dependence protecting the heart from ischemia-reperfusion injury. J. Cardiovasc. Pharmacol. 2014, 63, 477-487. [CrossRef] [PubMed]
-
(2014)
J. Cardiovasc. Pharmacol.
, vol.63
, pp. 477-487
-
-
Zepeda, R.1
Kuzmicic, J.2
Parra, V.3
Troncoso, R.4
Pennanen, C.5
Riquelme, J.A.6
Pedrozo, Z.7
Chiong, M.8
Sanchez, G.9
Lavandero, S.10
-
108
-
-
84894535372
-
Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: Therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission
-
CrossRef, PubMed
-
Sharp, W.W.; Fang, Y.H.; Han, M.; Zhang, H.J.; Hong, Z.; Banathy, A.; Morrow, E.; Ryan, J.J.; Archer, S.L. Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: Therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission. FASEB J. 2014, 28, 316-326. [CrossRef] [PubMed]
-
(2014)
FASEB J.
, vol.28
, pp. 316-326
-
-
Sharp, W.W.1
Fang, Y.H.2
Han, M.3
Zhang, H.J.4
Hong, Z.5
Banathy, A.6
Morrow, E.7
Ryan, J.J.8
Archer, S.L.9
-
109
-
-
84876048788
-
Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation
-
CrossRef, PubMed
-
Din, S.; Mason, M.; Volkers, M.; Johnson, B.; Cottage, C.T.; Wang, Z.; Joyo, A.Y.; Quijada, P.; Erhardt, P.; Magnuson, N.S.; et al. Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation. Proc. Natl. Acad. Sci. USA 2013, 110, 5969-5974. [CrossRef] [PubMed]
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 5969-5974
-
-
Din, S.1
Mason, M.2
Volkers, M.3
Johnson, B.4
Cottage, C.T.5
Wang, Z.6
Joyo, A.Y.7
Quijada, P.8
Erhardt, P.9
Magnuson, N.S.10
-
110
-
-
84987615915
-
Inhibition of Drp1 by Mdivi-1 attenuates cerebral ischemic injury via inhibition of the mitochondria-dependent apoptotic pathway after cardiac arrest
-
CrossRef, PubMed
-
Li, Y.; Wang, P.; Wei, J.; Fan, R.; Zuo, Y.; Shi, M.; Wu, H.; Zhou, M.; Lin, J.; Wu, M.; et al. Inhibition of Drp1 by Mdivi-1 attenuates cerebral ischemic injury via inhibition of the mitochondria-dependent apoptotic pathway after cardiac arrest. Neuroscience 2015, 311, 67-74. [CrossRef] [PubMed]
-
(2015)
Neuroscience
, vol.311
, pp. 67-74
-
-
Li, Y.1
Wang, P.2
Wei, J.3
Fan, R.4
Zuo, Y.5
Shi, M.6
Wu, H.7
Zhou, M.8
Lin, J.9
Wu, M.10
-
111
-
-
79956048283
-
A selective inhibitor of Drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina
-
CrossRef, PubMed
-
Park, S.W.; Kim, K.Y.; Lindsey, J.D.; Dai, Y.; Heo, H.; Nguyen, D.H.; Ellisman, M.H.;Weinreb, R.N.; Ju, W.K. A selective inhibitor of Drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina. Invest. Ophthalmol. Vis. Sci. 2011, 52, 2837-2843. [CrossRef] [PubMed]
-
(2011)
Invest. Ophthalmol. Vis. Sci.
, vol.52
, pp. 2837-2843
-
-
Park, S.W.1
Kim, K.Y.2
Lindsey, J.D.3
Dai, Y.4
Heo, H.5
Nguyen, D.H.6
Ellisman, M.H.7
Weinreb, R.N.8
Ju, W.K.9
-
112
-
-
84890943680
-
Necrostatin-1 attenuates ischemia injury induced cell death in rat tubular cell line NRK-52E through decreased Drp1 expression
-
CrossRef, PubMed
-
Zhang, L.; Jiang, F.; Chen, Y.; Luo, J.; Liu, S.; Zhang, B.; Ye, Z.; Wang, W.; Liang, X.; Shi, W. Necrostatin-1 attenuates ischemia injury induced cell death in rat tubular cell line NRK-52E through decreased Drp1 expression. Int. J. Mol. Sci. 2013, 14, 24742-24754. [CrossRef] [PubMed]
-
(2013)
Int. J. Mol. Sci.
, vol.14
, pp. 24742-24754
-
-
Zhang, L.1
Jiang, F.2
Chen, Y.3
Luo, J.4
Liu, S.5
Zhang, B.6
Ye, Z.7
Wang, W.8
Liang, X.9
Shi, W.10
-
113
-
-
84969248234
-
Peroxisome proliferator-activated receptor- dependent pathway reduces the phosphorylation of dynamin-related protein 1 and ameliorates hippocampal injury induced by global ischemia in rats
-
CrossRef, PubMed
-
Chuang, Y.C.; Lin, T.K.; Yang, D.I.; Yang, J.L.; Liou, C.W.; Chen, S.D. Peroxisome proliferator-activated receptor- dependent pathway reduces the phosphorylation of dynamin-related protein 1 and ameliorates hippocampal injury induced by global ischemia in rats. J. Biomed. Sci. 2016, 23, 44. [CrossRef] [PubMed]
-
(2016)
J. Biomed. Sci.
, vol.23
, pp. 44
-
-
Chuang, Y.C.1
Lin, T.K.2
Yang, D.I.3
Yang, J.L.4
Liou, C.W.5
Chen, S.D.6
-
114
-
-
84923355252
-
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
-
CrossRef, PubMed
-
Rappold, P.M.; Cui, M.; Grima, J.C.; Fan, R.Z.; de Mesy-Bentley, K.L.; Chen, L.; Zhuang, X.; Bowers, W.J.; Tieu, K. Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo. Nat. Commun. 2014, 5, 5244. [CrossRef] [PubMed]
-
(2014)
Nat. Commun.
, vol.5
, pp. 5244
-
-
Rappold, P.M.1
Cui, M.2
Grima, J.C.3
Fan, R.Z.4
De Mesy-Bentley, K.L.5
Chen, L.6
Zhuang, X.7
Bowers, W.J.8
Tieu, K.9
-
115
-
-
34250164631
-
Elevated hydrostatic pressure triggers mitochondrial fission and decreases cellular ATP in differentiated RGC-5 cells
-
CrossRef, PubMed
-
Ju, W.K.; Liu, Q.; Kim, K.Y.; Crowston, J.G.; Lindsey, J.D.; Agarwal, N.; Ellisman, M.H.; Perkins, G.A.; Weinreb, R.N. Elevated hydrostatic pressure triggers mitochondrial fission and decreases cellular ATP in differentiated RGC-5 cells. Invest. Ophthalmol. Vis. Sci. 2007, 48, 2145-2151. [CrossRef] [PubMed]
-
(2007)
Invest. Ophthalmol. Vis. Sci.
, vol.48
, pp. 2145-2151
-
-
Ju, W.K.1
Liu, Q.2
Kim, K.Y.3
Crowston, J.G.4
Lindsey, J.D.5
Agarwal, N.6
Ellisman, M.H.7
Perkins, G.A.8
Weinreb, R.N.9
-
116
-
-
84938765537
-
Drp1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma
-
CrossRef, PubMed
-
Kim, K.Y.; Perkins, G.A.; Shim, M.S.; Bushong, E.; Alcasid, N.; Ju, S.; Ellisman, M.H.; Weinreb, R.N.; Ju, W.K. Drp1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma. Cell Death Dis. 2015, 6, e1839. [CrossRef] [PubMed]
-
(2015)
Cell Death Dis.
, vol.6
-
-
Kim, K.Y.1
Perkins, G.A.2
Shim, M.S.3
Bushong, E.4
Alcasid, N.5
Ju, S.6
Ellisman, M.H.7
Weinreb, R.N.8
Ju, W.K.9
-
117
-
-
84873324504
-
Cyclosporine A-induced apoptosis in renal tubular cells is related to oxidative damage and mitochondrial fission
-
CrossRef, PubMed
-
De Arriba, G.; Calvino, M.; Benito, S.; Parra, T. Cyclosporine A-induced apoptosis in renal tubular cells is related to oxidative damage and mitochondrial fission. Toxicol. Lett. 2013, 218, 30-38. [CrossRef] [PubMed]
-
(2013)
Toxicol. Lett.
, vol.218
, pp. 30-38
-
-
De Arriba, G.1
Calvino, M.2
Benito, S.3
Parra, T.4
-
118
-
-
84889640326
-
Amelioration of rhabdomyolysis-induced renal mitochondrial injury and apoptosis through suppression of Drp-1 translocation
-
CrossRef, PubMed
-
Tang, W.X.; Wu, W.H.; Qiu, H.Y.; Bo, H.; Huang, S.M. Amelioration of rhabdomyolysis-induced renal mitochondrial injury and apoptosis through suppression of Drp-1 translocation. J. Nephrol. 2013, 26, 1073-1082. [CrossRef] [PubMed]
-
(2013)
J. Nephrol.
, vol.26
, pp. 1073-1082
-
-
Tang, W.X.1
Wu, W.H.2
Qiu, H.Y.3
Bo, H.4
Huang, S.M.5
-
119
-
-
84888378078
-
Cytoplasmic irradiation results in mitochondrial dysfunction and Drp1-dependent mitochondrial fission
-
CrossRef, PubMed
-
Zhang, B.; Davidson, M.M.; Zhou, H.;Wang, C.;Walker,W.F.; Hei, T.K. Cytoplasmic irradiation results in mitochondrial dysfunction and Drp1-dependent mitochondrial fission. Cancer Res. 2013, 73, 6700-6710. [CrossRef] [PubMed]
-
(2013)
Cancer Res.
, vol.73
, pp. 6700-6710
-
-
Zhang, B.1
Davidson, M.M.2
Zhou, H.3
Wang, C.4
Walker, W.F.5
Hei, T.K.6
-
120
-
-
84888296794
-
Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice
-
CrossRef, PubMed
-
Ramachandran, A.; McGill, M.R.; Xie, Y.; Ni, H.M.; Ding, W.X.; Jaeschke, H. Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice. Hepatology. 2013, 58, 2099-2108. [CrossRef] [PubMed]
-
(2013)
Hepatology.
, vol.58
, pp. 2099-2108
-
-
Ramachandran, A.1
McGill, M.R.2
Xie, Y.3
Ni, H.M.4
Ding, W.X.5
Jaeschke, H.6
-
121
-
-
85009844288
-
Early stage functions of mitochondrial autophagy and oxidative stress in acetaminophen-induced liver injury
-
CrossRef, PubMed
-
Gao, Y.; Chu, S.; Zhang, Z.; Zuo, W.; Xia, C.; Ai, Q.; Luo, P.; Cao, P.; Chen, N. Early stage functions of mitochondrial autophagy and oxidative stress in acetaminophen-induced liver injury. J. Cell. Biochem. 2016. [CrossRef] [PubMed]
-
(2016)
J. Cell. Biochem
-
-
Gao, Y.1
Chu, S.2
Zhang, Z.3
Zuo, W.4
Xia, C.5
Ai, Q.6
Luo, P.7
Cao, P.8
Chen, N.9
-
122
-
-
79958721260
-
Impaired mitochondrial dynamics and abnormal interaction of amyloid β with mitochondrial protein Drp1 in neurons from patients with Alzheimer’s disease: Implications for neuronal damage
-
CrossRef, PubMed
-
Manczak, M.; Calkins, M.J.; Reddy, P.H. Impaired mitochondrial dynamics and abnormal interaction of amyloid β with mitochondrial protein Drp1 in neurons from patients with Alzheimer’s disease: Implications for neuronal damage. Hum. Mol. Genet. 2011, 20, 2495-2509. [CrossRef] [PubMed]
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2495-2509
-
-
Manczak, M.1
Calkins, M.J.2
Reddy, P.H.3
-
123
-
-
84953303557
-
Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease
-
CrossRef, PubMed
-
Zhang, L.; Trushin, S.; Christensen, T.A.; Bachmeier, B.V.; Gateno, B.; Schroeder, A.; Yao, J.; Itoh, K.; Sesaki, H.; Poon, W.W.; et al. Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease. Sci. Rep. 2016, 6, 18725. [CrossRef] [PubMed]
-
(2016)
Sci. Rep.
, vol.6
, pp. 18725
-
-
Zhang, L.1
Trushin, S.2
Christensen, T.A.3
Bachmeier, B.V.4
Gateno, B.5
Schroeder, A.6
Yao, J.7
Itoh, K.8
Sesaki, H.9
Poon, W.W.10
-
124
-
-
84887004639
-
Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation
-
CrossRef, PubMed
-
Su, Y.C.; Qi, X. Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation. Hum. Mol. Genet. 2013, 22, 4545-4561. [CrossRef] [PubMed]
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 4545-4561
-
-
Su, Y.C.1
Qi, X.2
-
125
-
-
84872737271
-
Declines in Drp1 and parkin expression underlie DNA damage-induced changes in mitochondrial length and neuronal death
-
CrossRef, PubMed
-
Wang, D.B.; Garden, G.A.; Kinoshita, C.;Wyles, C.; Babazadeh, N.; Sopher, B.; Kinoshita, Y.; Morrison, R.S. Declines in Drp1 and parkin expression underlie DNA damage-induced changes in mitochondrial length and neuronal death. J. Neurosci. 2013, 33, 1357-1365. [CrossRef] [PubMed]
-
(2013)
J. Neurosci.
, vol.33
, pp. 1357-1365
-
-
Wang, D.B.1
Garden, G.A.2
Kinoshita, C.3
Wyles, C.4
Babazadeh, N.5
Sopher, B.6
Kinoshita, Y.7
Morrison, R.S.8
-
126
-
-
84971668159
-
Parkin suppresses Drp1-independent mitochondrial division
-
CrossRef, PubMed
-
Roy, M.; Itoh, K.; Iijima, M.; Sesaki, H. Parkin suppresses Drp1-independent mitochondrial division. Biochem. Biophys. Res. Commun. 2016, 475, 283-288. [CrossRef] [PubMed]
-
(2016)
Biochem. Biophys. Res. Commun.
, vol.475
, pp. 283-288
-
-
Roy, M.1
Itoh, K.2
Iijima, M.3
Sesaki, H.4
-
127
-
-
84872782873
-
N-terminal phosphorylation of protein phosphatase 2A/Bβ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival
-
CrossRef, PubMed
-
Merrill, R.A.; Slupe, A.M.; Strack, S. N-terminal phosphorylation of protein phosphatase 2A/Bβ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival. FEBS J. 2013, 280, 662-673. [CrossRef] [PubMed]
-
(2013)
FEBS J.
, vol.280
, pp. 662-673
-
-
Merrill, R.A.1
Slupe, A.M.2
Strack, S.3
-
128
-
-
84899069920
-
Cytotoxicity of ultrafine monodispersed nanoceria on human gastric cancer cells
-
CrossRef, PubMed
-
Li, C.; Zhao,W.; Liu, B.; Xu, G.; Liu, L.; Lv, H.; Shang, D.; Yang, D.; Damirin, A.; Zhang, J. Cytotoxicity of ultrafine monodispersed nanoceria on human gastric cancer cells. J. Biomed. Nanotechnol. 2014, 10, 1231-1241. [CrossRef] [PubMed]
-
(2014)
J. Biomed. Nanotechnol.
, vol.10
, pp. 1231-1241
-
-
Li, C.1
Zhao, W.2
Liu, B.3
Xu, G.4
Liu, L.5
Lv, H.6
Shang, D.7
Yang, D.8
Damirin, A.9
Zhang, J.10
-
129
-
-
84863728713
-
Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein
-
CrossRef, PubMed
-
Niu, J.; Yu, M.; Wang, C.; Xu, Z. Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein. J. Neurochem. 2012, 122, 650-658. [CrossRef] [PubMed]
-
(2012)
J. Neurochem.
, vol.122
, pp. 650-658
-
-
Niu, J.1
Yu, M.2
Wang, C.3
Xu, Z.4
-
130
-
-
84920505804
-
Blockage of GSK3β-mediated Drp1 phosphorylation provides neuroprotection in neuronal and mouse models of Alzheimer’s disease
-
CrossRef, PubMed
-
Yan, J.; Liu, X.H.; Han, M.Z.; Wang, Y.M.; Sun, X.L.; Yu, N.; Li, T.; Su, B.; Chen, Z.Y. Blockage of GSK3β-mediated Drp1 phosphorylation provides neuroprotection in neuronal and mouse models of Alzheimer’s disease. Neurobiol. Aging 2015, 36, 211-227. [CrossRef] [PubMed]
-
(2015)
Neurobiol. Aging
, vol.36
, pp. 211-227
-
-
Yan, J.1
Liu, X.H.2
Han, M.Z.3
Wang, Y.M.4
Sun, X.L.5
Yu, N.6
Li, T.7
Su, B.8
Chen, Z.Y.9
-
131
-
-
84900524027
-
Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle
-
CrossRef, PubMed
-
Aravamudan, B.; Kiel, A.; Freeman, M.; Delmotte, P.; Thompson, M.; Vassallo, R.; Sieck, G.C.; Pabelick, C.M.; Prakash, Y.S. Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle. Am. J. Physiol. Lung Cell. Mol. Physiol. 2014, 306, L840-L854. [CrossRef] [PubMed]
-
(2014)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.306
, pp. L840-L854
-
-
Aravamudan, B.1
Kiel, A.2
Freeman, M.3
Delmotte, P.4
Thompson, M.5
Vassallo, R.6
Sieck, G.C.7
Pabelick, C.M.8
Prakash, Y.S.9
-
132
-
-
84884735588
-
AMPK regulates ER morphology and function in stressed pancreatic β-cells via phosphorylation of Drp1
-
CrossRef, PubMed
-
Wikstrom, J.D.; Israeli, T.; Bachar-Wikstrom, E.; Swisa, A.; Ariav, Y.; Waiss, M.; Kaganovich, D.; Dor, Y.; Cerasi, E.; Leibowitz, G. AMPK regulates ER morphology and function in stressed pancreatic β-cells via phosphorylation of Drp1. Mol. Endocrinol. 2013, 27, 1706-1723. [CrossRef] [PubMed]
-
(2013)
Mol. Endocrinol.
, vol.27
, pp. 1706-1723
-
-
Wikstrom, J.D.1
Israeli, T.2
Bachar-Wikstrom, E.3
Swisa, A.4
Ariav, Y.5
Waiss, M.6
Kaganovich, D.7
Dor, Y.8
Cerasi, E.9
Leibowitz, G.10
-
133
-
-
84891715172
-
Rhein protects pancreatic β-cells from dynamin-related protein-1-mediated mitochondrial fission and cell apoptosis under hyperglycemia
-
CrossRef, PubMed
-
Liu, J.; Chen, Z.; Zhang, Y.; Zhang, M.; Zhu, X.; Fan, Y.; Shi, S.; Zen, K.; Liu, Z. Rhein protects pancreatic β-cells from dynamin-related protein-1-mediated mitochondrial fission and cell apoptosis under hyperglycemia. Diabetes 2013, 62, 3927-3935. [CrossRef] [PubMed]
-
(2013)
Diabetes
, vol.62
, pp. 3927-3935
-
-
Liu, J.1
Chen, Z.2
Zhang, Y.3
Zhang, M.4
Zhu, X.5
Fan, Y.6
Shi, S.7
Zen, K.8
Liu, Z.9
-
134
-
-
84877047169
-
Sabutoclax (BI97C1) and BI112D1, putative inhibitors of MCL-1, induce mitochondrial fragmentation either upstream of or independent of apoptosis
-
CrossRef, PubMed
-
Varadarajan, S.; Butterworth, M.; Wei, J.; Pellecchia, M.; Dinsdale, D.; Cohen, G.M. Sabutoclax (BI97C1) and BI112D1, putative inhibitors of MCL-1, induce mitochondrial fragmentation either upstream of or independent of apoptosis. Neoplasia 2013, 15, 568-578. [CrossRef] [PubMed]
-
(2013)
Neoplasia
, vol.15
, pp. 568-578
-
-
Varadarajan, S.1
Butterworth, M.2
Wei, J.3
Pellecchia, M.4
Dinsdale, D.5
Cohen, G.M.6
-
135
-
-
84925755753
-
Mitochondrial control by Drp1 in brain tumor initiating cells
-
CrossRef, PubMed
-
Xie, Q.;Wu, Q.; Horbinski, C.M.; Flavahan,W.A.; Yang, K.; Zhou,W.; Dombrowski, S.M.; Huang, Z.; Fang, X.; Shi, Y.; et al. Mitochondrial control by Drp1 in brain tumor initiating cells. Nat. Neurosci. 2015, 18, 501-510. [CrossRef] [PubMed]
-
(2015)
Nat. Neurosci.
, vol.18
, pp. 501-510
-
-
Xie, Q.1
Wu, Q.2
Horbinski, C.M.3
Flavahan, W.A.4
Yang, K.5
Zhou, W.6
Dombrowski, S.M.7
Huang, Z.8
Fang, X.9
Shi, Y.10
-
136
-
-
84926639320
-
Mitochondrial dynamics protein Drp1 is overexpressed in oncocytic thyroid tumors and regulates cancer cell migration
-
CrossRef, PubMed
-
Ferreira-da-Silva, A.; Valacca, C.; Rios, E.; Populo, H.; Soares, P.; Sobrinho-Simoes, M.; Scorrano, L.; Maximo, V.; Campello, S. Mitochondrial dynamics protein Drp1 is overexpressed in oncocytic thyroid tumors and regulates cancer cell migration. PLoS ONE 2015, 10, e0122308. [CrossRef] [PubMed]
-
(2015)
PLoS ONE
, vol.10
-
-
Ferreira-da-Silva, A.1
Valacca, C.2
Rios, E.3
Populo, H.4
Soares, P.5
Sobrinho-Simoes, M.6
Scorrano, L.7
Maximo, V.8
Campello, S.9
-
137
-
-
84994166850
-
Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma
-
CrossRef, PubMed
-
Zhan, L.; Cao, H.; Wang, G.; Lyu, Y.; Sun, X.; An, J.; Wu, Z.; Huang, Q.; Liu, B.; Xing, J. Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma. Oncotarget 2016, 7, 65001-65011. [CrossRef] [PubMed]
-
(2016)
Oncotarget
, vol.7
, pp. 65001-65011
-
-
Zhan, L.1
Cao, H.2
Wang, G.3
Lyu, Y.4
Sun, X.5
An, J.6
Wu, Z.7
Huang, Q.8
Liu, B.9
Xing, J.10
-
138
-
-
84907190373
-
Mitochondrial division inhibitor-1 induces mitochondrial hyperfusion and sensitizes human cancer cells to TRAIL-induced apoptosis
-
CrossRef, PubMed
-
Akita, M.; Suzuki-Karasaki, M.; Fujiwara, K.; Nakagawa, C.; Soma, M.; Yoshida, Y.; Ochiai, T.; Tokuhashi, Y.; Suzuki-Karasaki, Y. Mitochondrial division inhibitor-1 induces mitochondrial hyperfusion and sensitizes human cancer cells to TRAIL-induced apoptosis. Int. J. Oncol. 2014, 45, 1901-1912. [CrossRef] [PubMed]
-
(2014)
Int. J. Oncol.
, vol.45
, pp. 1901-1912
-
-
Akita, M.1
Suzuki-Karasaki, M.2
Fujiwara, K.3
Nakagawa, C.4
Soma, M.5
Yoshida, Y.6
Ochiai, T.7
Tokuhashi, Y.8
Suzuki-Karasaki, Y.9
-
139
-
-
84922702936
-
Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis
-
CrossRef, PubMed
-
Li, G.; Zhou, J.; Budhraja, A.; Hu, X.; Chen, Y.; Cheng, Q.; Liu, L.; Zhou, T.; Li, P.; Liu, E.; et al. Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis. Oncotarget 2015, 6, 1834-1849. [CrossRef] [PubMed]
-
(2015)
Oncotarget
, vol.6
, pp. 1834-1849
-
-
Li, G.1
Zhou, J.2
Budhraja, A.3
Hu, X.4
Chen, Y.5
Cheng, Q.6
Liu, L.7
Zhou, T.8
Li, P.9
Liu, E.10
-
140
-
-
84860339096
-
Depletion of mitochondrial fission factor Drp1 causes increased apoptosis in human colon cancer cells
-
CrossRef, PubMed
-
Inoue-Yamauchi, A.; Oda, H. Depletion of mitochondrial fission factor Drp1 causes increased apoptosis in human colon cancer cells. Biochem. Biophys. Res. Commun. 2012, 421, 81-85. [CrossRef] [PubMed]
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.421
, pp. 81-85
-
-
Inoue-Yamauchi, A.1
Oda, H.2
-
141
-
-
84900559241
-
Sodium butyrate induces Drp1-mediated mitochondrial fusion and apoptosis in human colorectal cancer cells
-
CrossRef, PubMed
-
Tailor, D.; Hahm, E.R.; Kale, R.K.; Singh, S.V.; Singh, R.P. Sodium butyrate induces Drp1-mediated mitochondrial fusion and apoptosis in human colorectal cancer cells. Mitochondrion 2014, 16, 55-64. [CrossRef] [PubMed]
-
(2014)
Mitochondrion
, vol.16
, pp. 55-64
-
-
Tailor, D.1
Hahm, E.R.2
Kale, R.K.3
Singh, S.V.4
Singh, R.P.5
-
142
-
-
84871458524
-
TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression
-
CrossRef, PubMed
-
Takamura, H.; Koyama, Y.; Matsuzaki, S.; Yamada, K.; Hattori, T.; Miyata, S.; Takemoto, K.; Tohyama, M.; Katayama, T. TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression. PLoS ONE 2012, 7, e51912. [CrossRef] [PubMed]
-
(2012)
PLoS ONE
, vol.7
-
-
Takamura, H.1
Koyama, Y.2
Matsuzaki, S.3
Yamada, K.4
Hattori, T.5
Miyata, S.6
Takemoto, K.7
Tohyama, M.8
Katayama, T.9
-
143
-
-
84941254697
-
Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis
-
CrossRef, PubMed
-
Wang, P.; Liu, B.; Zhao, J.; Pang, Q.; Agrawal, S.G.; Jia, L.; Liu, F.T. Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis. Oncotarget 2015, 6, 22598-22612. [CrossRef] [PubMed]
-
(2015)
Oncotarget
, vol.6
, pp. 22598-22612
-
-
Wang, P.1
Liu, B.2
Zhao, J.3
Pang, Q.4
Agrawal, S.G.5
Jia, L.6
Liu, F.T.7
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