Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming

Nature Communications

Volumn 7, Issue , 2016, Pages

  Prieto, Javier ^a   León, Marian ^a   Ponsoda, Xavier ^a   Sendra, Ramón ^a   Bort, Roque ^b   Ferrer Lorente, Raquel ^c,d,e   Raya, Angel ^c,d,e   López Garciá, Carlos ^a   Torres, Josema ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c Centre de Medicina Regenerativa de Barcelona   (Spain)

^d BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DRP1 PROTEIN; DUAL SPECIFICITY PHOSPHATASE 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; DNM1L PROTEIN, MOUSE; DYNAMIN; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; MYC PROTEIN, MOUSE; OCTAMER TRANSCRIPTION FACTOR 4; POU5F1 PROTEIN, MOUSE; SOX2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR SOX;

CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; FRAGMENTATION; INHIBITION; METABOLISM; MITOCHONDRION; MOLECULAR ANALYSIS; PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FLOW CYTOMETRY; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL FISSION; MITOCHONDRION; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PROTEIN PHOSPHORYLATION; SOMATIC CELL; ANIMAL; CELL LINE; CYTOLOGY; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

IPS;

ANIMALS; CELL LINE; CELLULAR REPROGRAMMING; DYNAMINS; INDUCED PLURIPOTENT STEM CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MAP KINASE SIGNALING SYSTEM; MICE; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; OCTAMER TRANSCRIPTION FACTOR-3; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-MYC; SOXB1 TRANSCRIPTION FACTORS;

EID: 84962920513     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11124     Document Type: Article

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