Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis

Hepatology

Volumn 62, Issue 6, 2015, Pages 1847-1857

  Dara, Lily ^a   Johnson, Heather ^a   Suda, Jo ^a   Win, Sanda ^a   Gaarde, William ^b   Han, Derick ^a,c   Kaplowitz, Neil ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b ISIS PHARMACEUTICALS   (United States)

^c KECK GRADUATE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DOCKING PROTEIN; DYNAMIN RELATED PROTEIN 1; MIXED LINEAGE KINASE; NECROSOME; NECROSTATIN; PARACETAMOL; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN SH3; RECEPTOR INTERACTING PROTEIN KINASE 1; SH3 HOMOLOGY 3 BINDING PROTEIN 5; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; MLKL PROTEIN, MOUSE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, MOUSE; RIPK3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOPLASM; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LIVER CELL; LIVER MITOCHONDRION; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; WILD TYPE; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL ORGANELLE; NECROSIS; PHYSIOLOGY;

ACETAMINOPHEN; ANIMALS; APOPTOSIS; MALE; MICE; MICE, INBRED C57BL; NECROSIS; ORGANELLES; PROTEIN KINASES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES;

EID: 84946778740     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27939     Document Type: Article

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