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Volumn 35, Issue 4, 2015, Pages 753-789

Perspectives on Biologically Active Camptothecin Derivatives

Author keywords

Biological activities; Camptothecins; DNA topoisomerase I; Structure activity relationship

Indexed keywords

10 HYDROXYCAMPTOTHECIN; 9 AMINOCAMPTOTHECIN; ANTIFUNGAL AGENT; ANTINEOPLASTIC AGENT; ANTIPARASITIC AGENT; ANTIPSORIASIS AGENT; ANTIVIRUS AGENT; CAMPTOTHECIN DERIVATIVE; FIRTECAN; IRINOTECAN; PESTICIDE; TOPOTECAN; ANTIINFECTIVE AGENT; CAMPTOTHECIN;

EID: 84930581497     PISSN: 01986325     EISSN: 10981128     Source Type: Journal    
DOI: 10.1002/med.21342     Document Type: Article
Times cited : (174)

References (152)
  • 1
    • 7144248725 scopus 로고
    • Plant antitumor agents I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata
    • Wall ME, Wani MC, Cook CE, Palmer KH, McPhail AT, Sim GA. Plant antitumor agents I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata. J Am Chem Soc 1966;88:3888-3890.
    • (1966) J Am Chem Soc , vol.88 , pp. 3888-3890
    • Wall, M.E.1    Wani, M.C.2    Cook, C.E.3    Palmer, K.H.4    McPhail, A.T.5    Sim, G.A.6
  • 3
    • 0015378084 scopus 로고
    • Phase I clinical trials of weekly and daily treatment with camptothecin (NSC 100880). Correlation with clinical studies
    • Muggia FM, Creaven PJ, Jansen HH, Cohen MN, Selawry DS. Phase I clinical trials of weekly and daily treatment with camptothecin (NSC 100880). Correlation with clinical studies. Cancer Chemother Rep 1972;56:515-521.
    • (1972) Cancer Chemother Rep , vol.56 , pp. 515-521
    • Muggia, F.M.1    Creaven, P.J.2    Jansen, H.H.3    Cohen, M.N.4    Selawry, D.S.5
  • 4
    • 0015291595 scopus 로고
    • Phase II study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer
    • Moertel CG, Schutt AJ, Reitemeier RJ, Hahn RG. Phase II study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer. Cancer Chemother Rep 1972;56:95-101.
    • (1972) Cancer Chemother Rep , vol.56 , pp. 95-101
    • Moertel, C.G.1    Schutt, A.J.2    Reitemeier, R.J.3    Hahn, R.G.4
  • 6
    • 0022340594 scopus 로고
    • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
    • Hsiang YH, Hertzberg R, Hecht S, Liu LF. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 1985;260:14873-14878.
    • (1985) J Biol Chem , vol.260 , pp. 14873-14878
    • Hsiang, Y.H.1    Hertzberg, R.2    Hecht, S.3    Liu, L.F.4
  • 8
    • 24144457231 scopus 로고    scopus 로고
    • Macromolecular and nanotechnological modification of camptothecin and its analogs to improve the efficacy
    • Onishi H, Machida Y. Macromolecular and nanotechnological modification of camptothecin and its analogs to improve the efficacy. Curr Drug Discover Technol 2005;2:169-183.
    • (2005) Curr Drug Discover Technol , vol.2 , pp. 169-183
    • Onishi, H.1    Machida, Y.2
  • 9
    • 0026487210 scopus 로고
    • Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors
    • Houghton PJ, Cheshire PJ, Myers L, Stewart CF, Synold TW, Houghton JA. Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors. Cancer Chemother Pharmacol 1992;31:229-232.
    • (1992) Cancer Chemother Pharmacol , vol.31 , pp. 229-232
    • Houghton, P.J.1    Cheshire, P.J.2    Myers, L.3    Stewart, C.F.4    Synold, T.W.5    Houghton, J.A.6
  • 10
    • 0023552964 scopus 로고
    • Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin, a novel water soluble derivative of camptothecin, against murine tumors
    • Kunimoto T, Nitta K, Tanaka T, Uehara N, Baba H, Takeuchi M, Yokokura T, Sawada S. Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin, a novel water soluble derivative of camptothecin, against murine tumors. Cancer Res 1987;47:5944-5948.
    • (1987) Cancer Res , vol.47 , pp. 5944-5948
    • Kunimoto, T.1    Nitta, K.2    Tanaka, T.3    Uehara, N.4    Baba, H.5    Takeuchi, M.6    Yokokura, T.7    Sawada, S.8
  • 11
    • 0033756761 scopus 로고    scopus 로고
    • Practical synthesis of (S)-7-(2-isopropylamino)ethylcamptothecin hydrochloride, potent topoisomerase I inhibitor
    • Ahn SK, Choi NS, Jeong BS, Kim KK, Journ DJ, Kim JK. Practical synthesis of (S)-7-(2-isopropylamino)ethylcamptothecin hydrochloride, potent topoisomerase I inhibitor. J Heterocycl Chem 2000;37:1141-1144.
    • (2000) J Heterocycl Chem , vol.37 , pp. 1141-1144
    • Ahn, S.K.1    Choi, N.S.2    Jeong, B.S.3    Kim, K.K.4    Journ, D.J.5    Kim, J.K.6
  • 12
    • 0023034927 scopus 로고
    • Plant antitumor agents 23. Synthesis and antileukemic activity of camptothecin analogs
    • Wani MC, Nicholas AW, Wall ME. Plant antitumor agents 23. Synthesis and antileukemic activity of camptothecin analogs. J Med Chem 1986;29:2358-2363.
    • (1986) J Med Chem , vol.29 , pp. 2358-2363
    • Wani, M.C.1    Nicholas, A.W.2    Wall, M.E.3
  • 13
    • 0037107555 scopus 로고    scopus 로고
    • The activity profile of the hexacyclic camptothecin derivative DX-8951f in experimental human colon cancer and ovarian cancer
    • van Hattum AH, Pinedo HM, Schluper HMM, Erkelens CAM, Tohgo A, Boven E. The activity profile of the hexacyclic camptothecin derivative DX-8951f in experimental human colon cancer and ovarian cancer. Biochem Pharm 2002;64:1267-1277.
    • (2002) Biochem Pharm , vol.64 , pp. 1267-1277
    • van Hattum, A.H.1    Pinedo, H.M.2    Schluper, H.M.M.3    Erkelens, C.A.M.4    Tohgo, A.5    Boven, E.6
  • 14
    • 1042268181 scopus 로고    scopus 로고
    • A phase II study of intravenous exatecan mesylate (DX- 8951f) administered daily for five days every three weeks to patients with metastatic adenocarcinoma of the colon or rectum
    • Royce ME, Rowinsky EK, Hoff PM, Coyle J, DeJager R, Pazdur R. A phase II study of intravenous exatecan mesylate (DX- 8951f) administered daily for five days every three weeks to patients with metastatic adenocarcinoma of the colon or rectum. Invest New Drugs 2004;22:53-61.
    • (2004) Invest New Drugs , vol.22 , pp. 53-61
    • Royce, M.E.1    Rowinsky, E.K.2    Hoff, P.M.3    Coyle, J.4    DeJager, R.5    Pazdur, R.6
  • 15
    • 0032956196 scopus 로고    scopus 로고
    • Phase I/pharmacokinetic study of the topoisomerase I inhibitor GG211 administered as a 21-day continuous infusion
    • Stevenson JP, DeMaria D, Sludden J, Kaye SB, Paz-Ares L, Grochow LB. Phase I/pharmacokinetic study of the topoisomerase I inhibitor GG211 administered as a 21-day continuous infusion. Ann Oncol 1999;10:339-344.
    • (1999) Ann Oncol , vol.10 , pp. 339-344
    • Stevenson, J.P.1    DeMaria, D.2    Sludden, J.3    Kaye, S.B.4    Paz-Ares, L.5    Grochow, L.B.6
  • 16
    • 12144290433 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of a low clearance, unilamellar liposomal formulation of lurtotecan, a topoisomerase I inhibitor, in patients with advanced leukemia
    • Giles FJ, Tallman MS, Guillermo GM, Cortes JE, Thomas DA, Wierda WG. Phase I and pharmacokinetic study of a low clearance, unilamellar liposomal formulation of lurtotecan, a topoisomerase I inhibitor, in patients with advanced leukemia. Cancer 2004;100:1449-1458.
    • (2004) Cancer , vol.100 , pp. 1449-1458
    • Giles, F.J.1    Tallman, M.S.2    Guillermo, G.M.3    Cortes, J.E.4    Thomas, D.A.5    Wierda, W.G.6
  • 17
    • 84930612362 scopus 로고    scopus 로고
    • inventors: Jiangsu Chia0tai Tianqing Pharmaceutical Co. Ltd, assignee. Pharmaceutical composition of camptothecin derivative and preparation method thereof. China Patent CN102764260.A. 2012. 11.7
    • Dong P, Zuo C, Chen ZL, Gao Y, inventors: Jiangsu Chia0tai Tianqing Pharmaceutical Co. Ltd, assignee. Pharmaceutical composition of camptothecin derivative and preparation method thereof. China Patent CN102764260.A. 2012. 11.7, 2012.
    • (2012)
    • Dong, P.1    Zuo, C.2    Chen, Z.L.3    Gao, Y.4
  • 18
    • 84894034802 scopus 로고    scopus 로고
    • Development and validation of a sensitive LC-MS/MS method for simultaneous quantification of sinotecan and its active metabolite in human blood
    • Yu Y, Zhan Y, Chen Z, Zhang, Y, Zhong D. Development and validation of a sensitive LC-MS/MS method for simultaneous quantification of sinotecan and its active metabolite in human blood. J Chromatogr B 2014;951-952:62-68.
    • (2014) J Chromatogr B , vol.951-952 , pp. 62-68
    • Yu, Y.1    Zhan, Y.2    Chen, Z.3    Zhang, Y.4    Zhong, D.5
  • 20
    • 0034514106 scopus 로고    scopus 로고
    • Feasibility, phase I, and pharmacological study of aerosolized liposomal 9-nitro-20(S)-camptothecin in patients with advanced malignancies in the lungs
    • Verschraegen CF, Gilbert BE, Huaringa AJ, Newman R, Harris N, Leyva FJ. Feasibility, phase I, and pharmacological study of aerosolized liposomal 9-nitro-20(S)-camptothecin in patients with advanced malignancies in the lungs. Ann N Y Acad Sci 2000;922:352-354.
    • (2000) Ann N Y Acad Sci , vol.922 , pp. 352-354
    • Verschraegen, C.F.1    Gilbert, B.E.2    Huaringa, A.J.3    Newman, R.4    Harris, N.5    Leyva, F.J.6
  • 21
    • 0034512495 scopus 로고    scopus 로고
    • The clinical development of 9-aminocamptothecin
    • Takimoto CH, Thomas R. The clinical development of 9-aminocamptothecin. Ann N Y Acad Sci 2000;922:224-236.
    • (2000) Ann N Y Acad Sci , vol.922 , pp. 224-236
    • Takimoto, C.H.1    Thomas, R.2
  • 22
    • 3142729057 scopus 로고    scopus 로고
    • Gimatecan, a novel camptothecin with a promising preclinical profile
    • Pratesi G, Beretta GL, Zunino F. Gimatecan, a novel camptothecin with a promising preclinical profile. Anticancer Drugs 2004;15:545-552.
    • (2004) Anticancer Drugs , vol.15 , pp. 545-552
    • Pratesi, G.1    Beretta, G.L.2    Zunino, F.3
  • 23
    • 84930612363 scopus 로고    scopus 로고
    • Preparation of highly lipophilic camptothecin derivatives. U.S. patent 6057303
    • Haridas, K, Hausheer, FH. Preparation of highly lipophilic camptothecin derivatives. U.S. patent 6057303, 2000.
    • (2000)
    • Haridas, K.1    Hausheer, F.H.2
  • 24
    • 0035816198 scopus 로고    scopus 로고
    • The highly lipophilic DNA topoisomerase I inhibitor DB-67 displays elevated lactone levels in human blood and potent anticancer activity
    • Bom D, Curran DP, Zhang J, Zimmer SG, Bevins R, Kruszewski S. The highly lipophilic DNA topoisomerase I inhibitor DB-67 displays elevated lactone levels in human blood and potent anticancer activity. J Control Release 2001;74:325-333.
    • (2001) J Control Release , vol.74 , pp. 325-333
    • Bom, D.1    Curran, D.P.2    Zhang, J.3    Zimmer, S.G.4    Bevins, R.5    Kruszewski, S.6
  • 25
    • 0035122238 scopus 로고    scopus 로고
    • The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison
    • Demarquay D, Huchet M, Coulomb H. The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison. Anticancer Drugs 2001;12:9-19.
    • (2001) Anticancer Drugs , vol.12 , pp. 9-19
    • Demarquay, D.1    Huchet, M.2    Coulomb, H.3
  • 28
    • 0035816202 scopus 로고    scopus 로고
    • Water-soluble poly-(L-glutamic acid)-Gly-camptothecin conjugates enhance camptothecin stability and efficacy in vivo
    • Singer JW, Bhatt R, Tulinsky J, Buhler KR, Heasley E, Klein P, de Vries P. Water-soluble poly-(L-glutamic acid)-Gly-camptothecin conjugates enhance camptothecin stability and efficacy in vivo. J Control Release 2001;74:243-247
    • (2001) J Control Release , vol.74 , pp. 243-247
    • Singer, J.W.1    Bhatt, R.2    Tulinsky, J.3    Buhler, K.R.4    Heasley, E.5    Klein, P.6    de Vries, P.7
  • 29
    • 0029948533 scopus 로고    scopus 로고
    • Drug delivery systems. 2. Camptothecin 20-O-polyethylene glycol ester transport forms
    • Greenwald RB, Pendri A, Conover C, Gilbert C, Yang R, Xia J. Drug delivery systems. 2. Camptothecin 20-O-polyethylene glycol ester transport forms. J Med Chem 1996;39:1938-1940.
    • (1996) J Med Chem , vol.39 , pp. 1938-1940
    • Greenwald, R.B.1    Pendri, A.2    Conover, C.3    Gilbert, C.4    Yang, R.5    Xia, J.6
  • 31
    • 0015850634 scopus 로고
    • Camptothecin
    • Schultz AG. Camptothecin. Chem Rev 1973;73:385-405.
    • (1973) Chem Rev , vol.73 , pp. 385-405
    • Schultz, A.G.1
  • 32
    • 0029971797 scopus 로고    scopus 로고
    • Camptothecin and taxol: From discovery to clinic
    • Wall ME, Wani MC. Camptothecin and taxol: From discovery to clinic. J Ethnopharmacol 1996;51:239-254.
    • (1996) J Ethnopharmacol , vol.51 , pp. 239-254
    • Wall, M.E.1    Wani, M.C.2
  • 33
    • 0032169909 scopus 로고    scopus 로고
    • Camptothecins: A review of their development and schedules of administration
    • Leary OJ, Muggia FM. Camptothecins: A review of their development and schedules of administration. Eur J Cancer 1998;34:1500-1508.
    • (1998) Eur J Cancer , vol.34 , pp. 1500-1508
    • Leary, O.J.1    Muggia, F.M.2
  • 34
    • 1442334562 scopus 로고    scopus 로고
    • Camptothecin and taxol: Historic achievements in natural products research
    • Oberlies NH, Kroll DJ. Camptothecin and taxol: Historic achievements in natural products research. J Nat Prod 2004;67:129-135.
    • (2004) J Nat Prod , vol.67 , pp. 129-135
    • Oberlies, N.H.1    Kroll, D.J.2
  • 35
    • 0038167666 scopus 로고    scopus 로고
    • The camptothecins
    • Pizzolato JF, Saltz LB. The camptothecins. Lancet 2003;361:2235-2242.
    • (2003) Lancet , vol.361 , pp. 2235-2242
    • Pizzolato, J.F.1    Saltz, L.B.2
  • 36
    • 4944264246 scopus 로고    scopus 로고
    • Camptothecin, over four decades of surprising findings
    • Lorence A, Nessler CL. Camptothecin, over four decades of surprising findings. Phytochem 2004;65:2735-2749
    • (2004) Phytochem , vol.65 , pp. 2735-2749
    • Lorence, A.1    Nessler, C.L.2
  • 39
    • 18044378364 scopus 로고    scopus 로고
    • Synthesis and pharmacology of new camptothecin drugs
    • Driver RW, Yang LX. Synthesis and pharmacology of new camptothecin drugs. Mini Rev Med Chem 2005;5:425-439.
    • (2005) Mini Rev Med Chem , vol.5 , pp. 425-439
    • Driver, R.W.1    Yang, L.X.2
  • 40
    • 0036759731 scopus 로고    scopus 로고
    • Milestones in camptothecin research
    • Lerchen HG. Milestones in camptothecin research. Drugs Future 2002;27:869-878.
    • (2002) Drugs Future , vol.27 , pp. 869-878
    • Lerchen, H.G.1
  • 41
    • 19144361907 scopus 로고    scopus 로고
    • Camptothecin and its analogues: A review on their chemotherapeutic potential
    • Sriram D, Yogeeswari P, Thirumurugan R, Bal TR. Camptothecin and its analogues: A review on their chemotherapeutic potential. Nat Prod Res 2005;19:393-412.
    • (2005) Nat Prod Res , vol.19 , pp. 393-412
    • Sriram, D.1    Yogeeswari, P.2    Thirumurugan, R.3    Bal, T.R.4
  • 42
    • 33749034730 scopus 로고    scopus 로고
    • Topoisomerase I inhibitors: Camptothecins and beyond
    • Pommier Y. Topoisomerase I inhibitors: Camptothecins and beyond. Nat Rev Cancer 2006;6:789-802.
    • (2006) Nat Rev Cancer , vol.6 , pp. 789-802
    • Pommier, Y.1
  • 48
    • 62849118422 scopus 로고    scopus 로고
    • Synthesis and cytotoxic activity of 7-alkynyl camptothecin derivatives
    • Xiao F, Xue YD, Luo Y, Zhang B, Lu W, Yang B. Synthesis and cytotoxic activity of 7-alkynyl camptothecin derivatives. Chin Chem Lett 2009;20:566-568.
    • (2009) Chin Chem Lett , vol.20 , pp. 566-568
    • Xiao, F.1    Xue, Y.D.2    Luo, Y.3    Zhang, B.4    Lu, W.5    Yang, B.6
  • 49
    • 33748754360 scopus 로고    scopus 로고
    • Synthesis and antitumor activity of novel 10-substituted camptothecin analogues
    • Li QY, Zu YG, Shi RZ, Yao LP, Fu YJ, Yang ZW, Li L. Synthesis and antitumor activity of novel 10-substituted camptothecin analogues. Bioorg Med Chem 2006;14:7175-7182.
    • (2006) Bioorg Med Chem , vol.14 , pp. 7175-7182
    • Li, Q.Y.1    Zu, Y.G.2    Shi, R.Z.3    Yao, L.P.4    Fu, Y.J.5    Yang, Z.W.6    Li, L.7
  • 50
    • 79952489150 scopus 로고    scopus 로고
    • Synthesis and antitumor activity of 10-arylcamptothecin derivatives
    • Jiao Y, Liu HC, Geng MY, Duan WH. Synthesis and antitumor activity of 10-arylcamptothecin derivatives. Bioorg Med Chem Lett 2011;21:2071-2074.
    • (2011) Bioorg Med Chem Lett , vol.21 , pp. 2071-2074
    • Jiao, Y.1    Liu, H.C.2    Geng, M.Y.3    Duan, W.H.4
  • 52
    • 47149110371 scopus 로고    scopus 로고
    • Novel hexacyclic camptothecin derivatives. Part 1: Synthesis and cytotoxicity of camptothecins with an A-ring fused 1, 3-oxazine ring
    • Wang S, Li YY, Liu YH, Lu AJ, You QD. Novel hexacyclic camptothecin derivatives. Part 1: Synthesis and cytotoxicity of camptothecins with an A-ring fused 1, 3-oxazine ring. Bioorg Med Chem Lett 2008;18:4095-4097.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 4095-4097
    • Wang, S.1    Li, Y.Y.2    Liu, Y.H.3    Lu, A.J.4    You, Q.D.5
  • 54
    • 41149117548 scopus 로고    scopus 로고
    • Benzyl ether-linked glucuronide derivative of 10-hydroxycamptothecin designed for selective camptothecin-based anticancer therapy
    • Leu YL, Chen CS, Wu YJ, Chern JW. Benzyl ether-linked glucuronide derivative of 10-hydroxycamptothecin designed for selective camptothecin-based anticancer therapy. J Med Chem 2008;51:1740-1746.
    • (2008) J Med Chem , vol.51 , pp. 1740-1746
    • Leu, Y.L.1    Chen, C.S.2    Wu, Y.J.3    Chern, J.W.4
  • 55
    • 84930612364 scopus 로고
    • Camptothecin intermediate and method of making camptothecin intermediates US patent 5459269
    • Comins DL. Camptothecin intermediate and method of making camptothecin intermediates US patent 5459269, 1995.
    • (1995)
    • Comins, D.L.1
  • 56
    • 0026316167 scopus 로고
    • Synthesis and antitumor activity of 20(S)-camptothecin derivatives: A-ring modified and 7,10-disubstituted camptothecins
    • Sawada S, Matsuoka S, Nokata K, Nagata H, Furata T, Yokokura T, Miyasaka T. Synthesis and antitumor activity of 20(S)-camptothecin derivatives: A-ring modified and 7, 10-disubstituted camptothecins. Chem Pharm Bull 1991;12:3183-3188.
    • (1991) Chem Pharm Bull , vol.12 , pp. 3183-3188
    • Sawada, S.1    Matsuoka, S.2    Nokata, K.3    Nagata, H.4    Furata, T.5    Yokokura, T.6    Miyasaka, T.7
  • 57
    • 33748959201 scopus 로고    scopus 로고
    • Preparation of 14-nitrocamptothecin derivatives by reactions of camptothecin with nitronium tetrafluoroborate in acidic solvents
    • Cao ZS. Preparation of 14-nitrocamptothecin derivatives by reactions of camptothecin with nitronium tetrafluoroborate in acidic solvents. J Chem Soc Perkin Trans I 1996;1:2629-2631.
    • (1996) J Chem Soc Perkin Trans I , vol.1 , pp. 2629-2631
    • Cao, Z.S.1
  • 61
    • 0033591764 scopus 로고    scopus 로고
    • Novel C-ring analogues of 20(S)-camptothecin. Part-2: Synthesis and in vitro cytotoxicity of 5-C-substituted 20(S)-camptothecin analogues
    • Subrahmanyam D, Venkateswarlu A, Rao KV, Sastrya TVRS, Vandana G, Kumar SA. Novel C-ring analogues of 20(S)-camptothecin. Part-2: Synthesis and in vitro cytotoxicity of 5-C-substituted 20(S)-camptothecin analogues. Bioorg Med Chem Lett 1999;9:1633-1638.
    • (1999) Bioorg Med Chem Lett , vol.9 , pp. 1633-1638
    • Subrahmanyam, D.1    Venkateswarlu, A.2    Rao, K.V.3    Sastrya, T.V.R.S.4    Vandana, G.5    Kumar, S.A.6
  • 65
    • 64349103354 scopus 로고    scopus 로고
    • Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins
    • Samori C, Guerrini A, Varchi G, Fontana G, Bombardelli E, Tinelli S. Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins. J Med Chem 2009;52:1029-1039.
    • (2009) J Med Chem , vol.52 , pp. 1029-1039
    • Samori, C.1    Guerrini, A.2    Varchi, G.3    Fontana, G.4    Bombardelli, E.5    Tinelli, S.6
  • 66
    • 77249149967 scopus 로고    scopus 로고
    • A series of α-amino acid ester prodrugs of camptothecin: In vitro hydrolysis and A-549 human lung carcinoma cell cytotoxicity
    • Deshmukh M, Chao PY, Kutscher HL, Gao DY, Sinko PJ. A series of α-amino acid ester prodrugs of camptothecin: In vitro hydrolysis and A-549 human lung carcinoma cell cytotoxicity. J Med Chem 2010;53:1038-1047.
    • (2010) J Med Chem , vol.53 , pp. 1038-1047
    • Deshmukh, M.1    Chao, P.Y.2    Kutscher, H.L.3    Gao, D.Y.4    Sinko, P.J.5
  • 67
    • 2942608090 scopus 로고    scopus 로고
    • Synthesis and antitumor activity of 20-O-linked nitrogen-based camptothecin ester derivatives
    • Wang CY, Pan XD, Liu HY, Fu ZD, Wei XY, Yang LX. Synthesis and antitumor activity of 20-O-linked nitrogen-based camptothecin ester derivatives. Bioorg Med Chem 2004;12:3657-3662.
    • (2004) Bioorg Med Chem , vol.12 , pp. 3657-3662
    • Wang, C.Y.1    Pan, X.D.2    Liu, H.Y.3    Fu, Z.D.4    Wei, X.Y.5    Yang, L.X.6
  • 69
    • 54049097186 scopus 로고    scopus 로고
    • First synthesis of novel spin-labeled derivatives of camptothecin as potential antineoplastic agents
    • Liu YQ, Tian X, Yang L, Zhan ZC. First synthesis of novel spin-labeled derivatives of camptothecin as potential antineoplastic agents. Eur J Med Chem 2008;43:2610-2614.
    • (2008) Eur J Med Chem , vol.43 , pp. 2610-2614
    • Liu, Y.Q.1    Tian, X.2    Yang, L.3    Zhan, Z.C.4
  • 70
    • 12844270595 scopus 로고    scopus 로고
    • On the role of E-ring oxygen atoms in the binding of camptothecin to the topoisomerase I-DNA covalent binary complex
    • Rahier NJ, Eisenhauer BM, Gao R, Thomas SJ, Hecht SM. On the role of E-ring oxygen atoms in the binding of camptothecin to the topoisomerase I-DNA covalent binary complex. Bioorg Med Chem 2005;13:1381-1386.
    • (2005) Bioorg Med Chem , vol.13 , pp. 1381-1386
    • Rahier, N.J.1    Eisenhauer, B.M.2    Gao, R.3    Thomas, S.J.4    Hecht, S.M.5
  • 71
    • 0033564494 scopus 로고    scopus 로고
    • Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties
    • Lesueur-Ginot L, Demarquay D, Kiss R. Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties. Cancer Res 1999;59:2939-2943.
    • (1999) Cancer Res , vol.59 , pp. 2939-2943
    • Lesueur-Ginot, L.1    Demarquay, D.2    Kiss, R.3
  • 72
    • 0034214095 scopus 로고    scopus 로고
    • Preparation and in vitro activity of enantiomerically pure, fluorinated homocamptothecins as potent topoisomerase I poisons
    • Lavergne O, Demarquay D, Bailly C. Preparation and in vitro activity of enantiomerically pure, fluorinated homocamptothecins as potent topoisomerase I poisons. J Med Chem 2000;43:2285-2289.
    • (2000) J Med Chem , vol.43 , pp. 2285-2289
    • Lavergne, O.1    Demarquay, D.2    Bailly, C.3
  • 73
    • 0035300590 scopus 로고    scopus 로고
    • Unusual potency of BN80915, a novel fluorinated E-ring modified camptothecin, towards human colon carcinoma cells
    • Larsen A, Gilbert C, Chyzak G. Unusual potency of BN80915, a novel fluorinated E-ring modified camptothecin, towards human colon carcinoma cells. Cancer Res 2001;61:2961-2967.
    • (2001) Cancer Res , vol.61 , pp. 2961-2967
    • Larsen, A.1    Gilbert, C.2    Chyzak, G.3
  • 74
    • 77950859671 scopus 로고    scopus 로고
    • Synthesis and evaluation of 9-benzylideneamino derivatives of homocamptothecin as potent inhibitors of DNA topoisomerase I
    • Guo W, Miao ZY, Sheng CQ, Yao JZ, Feng H. Synthesis and evaluation of 9-benzylideneamino derivatives of homocamptothecin as potent inhibitors of DNA topoisomerase I. Eur J Med Chem 2010;45:2223-2228.
    • (2010) Eur J Med Chem , vol.45 , pp. 2223-2228
    • Guo, W.1    Miao, Z.Y.2    Sheng, C.Q.3    Yao, J.Z.4    Feng, H.5
  • 75
    • 84862534440 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors
    • Zhu LJ, Zhang XH, Lei N. Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors. Chem Biodivers 2012;9:1084-1094.
    • (2012) Chem Biodivers , vol.9 , pp. 1084-1094
    • Zhu, L.J.1    Zhang, X.H.2    Lei, N.3
  • 76
    • 77951203595 scopus 로고    scopus 로고
    • Phosphate ester derivatives of homocamptothecin: synthesis, solution stabilities and antitumor activities
    • Miao ZY, Zhang J, You L, Wang J, Sheng CQ, Yao JZ. Phosphate ester derivatives of homocamptothecin: synthesis, solution stabilities and antitumor activities. Bioorg Med Chem 2010;18:3140-3146.
    • (2010) Bioorg Med Chem , vol.18 , pp. 3140-3146
    • Miao, Z.Y.1    Zhang, J.2    You, L.3    Wang, J.4    Sheng, C.Q.5    Yao, J.Z.6
  • 77
    • 84865470016 scopus 로고    scopus 로고
    • Synthesis and preliminary bioevaluation of novel E-ring modified acetal analog of camptothecin as cytotoxic agents
    • Zhu LJ, Zhuang CL, Lei N, Guo ZZ, Sheng CQ, Dong GQ. Synthesis and preliminary bioevaluation of novel E-ring modified acetal analog of camptothecin as cytotoxic agents. Eur J Med Chem 2012;56:1-9.
    • (2012) Eur J Med Chem , vol.56 , pp. 1-9
    • Zhu, L.J.1    Zhuang, C.L.2    Lei, N.3    Guo, Z.Z.4    Sheng, C.Q.5    Dong, G.Q.6
  • 78
    • 84864415641 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of new homocamptothecin analogs
    • Luo Y, Yu SB, Tong LJ, Huang QQ, Lu W, Chen Y. Synthesis and biological evaluation of new homocamptothecin analogs. Eur J Med Chem 2012;54:281-286.
    • (2012) Eur J Med Chem , vol.54 , pp. 281-286
    • Luo, Y.1    Yu, S.B.2    Tong, L.J.3    Huang, Q.Q.4    Lu, W.5    Chen, Y.6
  • 79
    • 79955589507 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of novel 7-acyl homocamptothecins as topoisomerase I inhibitors
    • Liu WF, Zhu LJ, Guo W, Zhuang CL, Zhang YQ. Synthesis and biological evaluation of novel 7-acyl homocamptothecins as topoisomerase I inhibitors. Eur J Med Chem 2011;46:2408-2414.
    • (2011) Eur J Med Chem , vol.46 , pp. 2408-2414
    • Liu, W.F.1    Zhu, L.J.2    Guo, W.3    Zhuang, C.L.4    Zhang, Y.Q.5
  • 80
    • 56249121861 scopus 로고    scopus 로고
    • Semi-synthesis and biological activity of β-lactones analogs of camptothecin
    • Li MZ, Tang WD, Zeng FX, Lou LG, You TP. Semi-synthesis and biological activity of β-lactones analogs of camptothecin. Bioorg Med Chem Lett 2008;18:6441-6443.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 6441-6443
    • Li, M.Z.1    Tang, W.D.2    Zeng, F.X.3    Lou, L.G.4    You, T.P.5
  • 83
    • 0020072467 scopus 로고
    • DNA processing activities associated with the purified α, β2, αβ2 molecular forms of avian sarcoma virus RNA-dependent DNA polymerase
    • Hizi A, Gazit A, Buthmann D, Yaniv A. DNA processing activities associated with the purified α, β2, αβ2 molecular forms of avian sarcoma virus RNA-dependent DNA polymerase. J Virol 1982;141:974-981.
    • (1982) J Virol , vol.141 , pp. 974-981
    • Hizi, A.1    Gazit, A.2    Buthmann, D.3    Yaniv, A.4
  • 84
    • 84930612365 scopus 로고
    • In: Molecular Biology of Tumor Viruses: RNA Tumor Viruses, 2nd ed. New York: Cold Spring Harbor; .
    • Weiss R, Teich N, Varmus H, Coffin J. In: Molecular Biology of Tumor Viruses: RNA Tumor Viruses, 2nd ed. New York: Cold Spring Harbor; 1985.
    • (1985)
    • Weiss, R.1    Teich, N.2    Varmus, H.3    Coffin, J.4
  • 86
    • 0025187440 scopus 로고
    • Topoisomerase I activity associated with human immunodeficiency virus (HIV) particles and equine infectious anemia virus core
    • Priel E, Showalter SD, Roberts M, Oroszlan S, Segar S, Aboud M, Blair DG. Topoisomerase I activity associated with human immunodeficiency virus (HIV) particles and equine infectious anemia virus core. EMBO J 1990;12:4167-4172.
    • (1990) EMBO J , vol.12 , pp. 4167-4172
    • Priel, E.1    Showalter, S.D.2    Roberts, M.3    Oroszlan, S.4    Segar, S.5    Aboud, M.6    Blair, D.G.7
  • 87
    • 0030062084 scopus 로고    scopus 로고
    • Camptothecin: A promising antiretroviral drug
    • Pantazis P. Camptothecin: A promising antiretroviral drug. J Biomed Sci 1996;3:14-19.
    • (1996) J Biomed Sci , vol.3 , pp. 14-19
    • Pantazis, P.1
  • 88
    • 0015150039 scopus 로고
    • Studies on camptothecin: Effects on nucleic acid and protein synthesis
    • Horwitz SB, Chang CK, Grollman AP. Studies on camptothecin: Effects on nucleic acid and protein synthesis. Mol Pharmacol 1971;7:632-644.
    • (1971) Mol Pharmacol , vol.7 , pp. 632-644
    • Horwitz, S.B.1    Chang, C.K.2    Grollman, A.P.3
  • 90
    • 0026082794 scopus 로고
    • Inhibition of human immunodeficiency virus (HIV-1) replication by noncytotoxic doses of camptothecin, a topoisomerase I inhibitor
    • Priel E, Showalter SD, Blair DG. Inhibition of human immunodeficiency virus (HIV-1) replication by noncytotoxic doses of camptothecin, a topoisomerase I inhibitor. AIDS Res Hum Retroviruses 1991;7:65-72.
    • (1991) AIDS Res Hum Retroviruses , vol.7 , pp. 65-72
    • Priel, E.1    Showalter, S.D.2    Blair, D.G.3
  • 91
    • 0025850677 scopus 로고
    • The topoisomerase I inhibitor, camptothecin, inhibits equine infectious anemia virus replication in chronically infected CF2Th cells
    • Priel E, Showalter SD, Roberts M, Oroszlan S, Blair DG. The topoisomerase I inhibitor, camptothecin, inhibits equine infectious anemia virus replication in chronically infected CF2Th cells. J Virol 1991;65:4137-4141.
    • (1991) J Virol , vol.65 , pp. 4137-4141
    • Priel, E.1    Showalter, S.D.2    Roberts, M.3    Oroszlan, S.4    Blair, D.G.5
  • 92
    • 0001792440 scopus 로고
    • In: Fields BN, Knipe DM, Chanock RM, Hirsch MS, Melnick JL, Monath TP, Roizman B, eds. Virology, New York: Raven Press
    • Wong-Staal F. Human immunodeficiency viruses and their replication. In: Fields BN, Knipe DM, Chanock RM, Hirsch MS, Melnick JL, Monath TP, Roizman B, eds. Virology, Vol 2. New York: Raven Press; 1990. p 1529-1543.
    • (1990) Human immunodeficiency viruses and their replication , vol.2 , pp. 1529-1543
    • Wong-Staal, F.1
  • 93
    • 0027403716 scopus 로고
    • Three inhibitors of type 1 human immunodeficiency virus long terminal repeat directed gene expression and virus replication
    • Li CJ, Zhang LJ, Dezube B J, Crumpacker CS, Pardee AB. Three inhibitors of type 1 human immunodeficiency virus long terminal repeat directed gene expression and virus replication. Proc Natl Acad Sci USA 1993;90:1839-1842.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1839-1842
    • Li, C.J.1    Zhang, L.J.2    Dezube, B.J.3    Crumpacker, C.S.4    Pardee, A.B.5
  • 95
    • 0033023748 scopus 로고    scopus 로고
    • 9-Nitrocamptothecin selectively inhibits human immunodeficiency virus type 1 replication in freshly infected parental but not 9-nitrocamptothecin-resistant U937 monocytoid cells
    • Sadaie MR, Doniger J, Hung CL, Pantazis P. 9-Nitrocamptothecin selectively inhibits human immunodeficiency virus type 1 replication in freshly infected parental but not 9-nitrocamptothecin-resistant U937 monocytoid cells. AIDS Res Hum Retrovirus 1999;15:239-245.
    • (1999) AIDS Res Hum Retrovirus , vol.15 , pp. 239-245
    • Sadaie, M.R.1    Doniger, J.2    Hung, C.L.3    Pantazis, P.4
  • 97
    • 0030062084 scopus 로고    scopus 로고
    • Camptothecin: A promising antiretroviral drug
    • Pantazis P. Camptothecin: A promising antiretroviral drug. J Biomed Sci 1996;3:14-19.
    • (1996) J Biomed Sci , vol.3 , pp. 14-19
    • Pantazis, P.1
  • 99
    • 0025309604 scopus 로고
    • Role of DNA topoisomerase I in the replication of herpes simplex virus type 2
    • Yamada Y, Yamamoto N, Maeno K, Nishiyama Y. Role of DNA topoisomerase I in the replication of herpes simplex virus type 2. Arch Virol 1990;110:121-127.
    • (1990) Arch Virol , vol.110 , pp. 121-127
    • Yamada, Y.1    Yamamoto, N.2    Maeno, K.3    Nishiyama, Y.4
  • 100
    • 0032576798 scopus 로고    scopus 로고
    • Two efficient methods for the conversion of camptothecin to mappicine ketone, an antiviral lead compound
    • Das B, Madhusudhan P, Kashinatham A. Two efficient methods for the conversion of camptothecin to mappicine ketone, an antiviral lead compound. Tetrahedron Lett 1998;39:431-432.
    • (1998) Tetrahedron Lett , vol.39 , pp. 431-432
    • Das, B.1    Madhusudhan, P.2    Kashinatham, A.3
  • 101
    • 0034966673 scopus 로고    scopus 로고
    • Antiviral drugs: Current state of the art
    • de Clercq E. Antiviral drugs: Current state of the art. J Clin Virol 2001;22:73-89.
    • (2001) J Clin Virol , vol.22 , pp. 73-89
    • Clercq, E.1
  • 102
    • 0029036345 scopus 로고
    • Synthesis and anti-HSV activity of methylenedioxy mappicine ketone analogs
    • Pendrak I, Wittrock R, Kingsbury WD. Synthesis and anti-HSV activity of methylenedioxy mappicine ketone analogs. J Org Chem 1995;60:2912-2915.
    • (1995) J Org Chem , vol.60 , pp. 2912-2915
    • Pendrak, I.1    Wittrock, R.2    Kingsbury, W.D.3
  • 103
    • 77951239927 scopus 로고    scopus 로고
    • Anti-HSV activity of camptothecin analogues
    • Liu YQ, Liu ZL, Tian X, Yang L. Anti-HSV activity of camptothecin analogues. Nat Prod Res 2010;24:509-514.
    • (2010) Nat Prod Res , vol.24 , pp. 509-514
    • Liu, Y.Q.1    Liu, Z.L.2    Tian, X.3    Yang, L.4
  • 104
    • 0016073948 scopus 로고
    • Camptothecin, a potent chemosterilant against the house fly
    • DeMilo AB, Borkovec AB. Camptothecin, a potent chemosterilant against the house fly. J Econ Entomol 1974;67:457-458.
    • (1974) J Econ Entomol , vol.67 , pp. 457-458
    • DeMilo, A.B.1    Borkovec, A.B.2
  • 105
    • 0017101655 scopus 로고
    • Control and management of insect populations by chemosterilants
    • Borkovec AB. Control and management of insect populations by chemosterilants. Environ Health Perspect 1976;14:103-107.
    • (1976) Environ Health Perspect , vol.14 , pp. 103-107
    • Borkovec, A.B.1
  • 106
    • 84858072980 scopus 로고    scopus 로고
    • Field efficiency trials on Empoasca vitis Gothe with extractive from the leaf of Camptotheca acuminate
    • Hu Q, Han BY, Ma JY, Tang D, Yang J. Field efficiency trials on Empoasca vitis Gothe with extractive from the leaf of Camptotheca acuminate. China Tea 2009;31:32-33.
    • (2009) China Tea , vol.31 , pp. 32-33
    • Hu, Q.1    Han, B.Y.2    Ma, J.Y.3    Tang, D.4    Yang, J.5
  • 107
    • 84858075143 scopus 로고    scopus 로고
    • Insecticidal effect of camptothecin against Nilaparvata lugens, Brevicoryne brassicae and Chilo suppressalis Walker
    • Tong SM, Wang PW, Sun YZ, Zhang LQ, Ma JY, Sheng XQ. Insecticidal effect of camptothecin against Nilaparvata lugens, Brevicoryne brassicae and Chilo suppressalis Walker. Acta Agri Zhejiangensis 2009;21:288-292.
    • (2009) Acta Agri Zhejiangensis , vol.21 , pp. 288-292
    • Tong, S.M.1    Wang, P.W.2    Sun, Y.Z.3    Zhang, L.Q.4    Ma, J.Y.5    Sheng, X.Q.6
  • 108
    • 84930612366 scopus 로고    scopus 로고
    • Insecticidal activity of camptothecin derivatives. Plant protection science and technology innovation and pest prevention and control specialization. China Plant Protection Association 2011 Annual Conference Proceedings, 2011.
    • de L, Jiang HY, Zhang YN, Zhang L, He WZ. Insecticidal activity of camptothecin derivatives. Plant protection science and technology innovation and pest prevention and control specialization. China Plant Protection Association 2011 Annual Conference Proceedings, 2011.
    • de, L.1    Jiang, H.Y.2    Zhang, Y.N.3    Zhang, L.4    He, W.Z.5
  • 109
    • 77952295906 scopus 로고    scopus 로고
    • Insecticidal activity of camptothecin against Nilaparvata lugens, Brevicoryne brassicae, and Chilo suppressalis
    • Ma JY, Tong SM, Wang PW, Liao WL, Liu HB, Zhang LQ. Insecticidal activity of camptothecin against Nilaparvata lugens, Brevicoryne brassicae, and Chilo suppressalis. J Econ Entomol 2010;103:492-496.
    • (2010) J Econ Entomol , vol.103 , pp. 492-496
    • Ma, J.Y.1    Tong, S.M.2    Wang, P.W.3    Liao, W.L.4    Liu, H.B.5    Zhang, L.Q.6
  • 110
    • 84865267861 scopus 로고    scopus 로고
    • The utility of camptothecin as a synergist of Bacillus thuringiensis var. kurstaki and nucleopolyhedroviruses against Trichoplusia ni and Spodoptera exigua
    • Sun SF, Cheng ZS, Fan J, Cheng XH, Pang Y. The utility of camptothecin as a synergist of Bacillus thuringiensis var. kurstaki and nucleopolyhedroviruses against Trichoplusia ni and Spodoptera exigua. J Econ Entomol 2012;105:1164-1170.
    • (2012) J Econ Entomol , vol.105 , pp. 1164-1170
    • Sun, S.F.1    Cheng, Z.S.2    Fan, J.3    Cheng, X.H.4    Pang, Y.5
  • 111
  • 112
    • 84858080114 scopus 로고    scopus 로고
    • Effects of camptothecin and hydroxycamptothecin on insect cell lines Sf21 and IOZCAS-Spex-II
    • Zhang L, Zhang YN, He WZ, Ma DJ, Jiang HY. Effects of camptothecin and hydroxycamptothecin on insect cell lines Sf21 and IOZCAS-Spex-II. Pest Manag Sci 2012;68:652-657.
    • (2012) Pest Manag Sci , vol.68 , pp. 652-657
    • Zhang, L.1    Zhang, Y.N.2    He, W.Z.3    Ma, D.J.4    Jiang, H.Y.5
  • 113
    • 84874339036 scopus 로고    scopus 로고
    • Characterization of DNA topoisomerase-1 in Spodoptera exigua for toxicity evaluation of camptothecin and hydroxycamptothecin
    • Zhang L, Ma DJ, Zhang YN, He WZ, Yang JJ, Li CR, Jiang HY. Characterization of DNA topoisomerase-1 in Spodoptera exigua for toxicity evaluation of camptothecin and hydroxycamptothecin. PLoS One 2013;8:e56458.
    • (2013) PLoS One , vol.8 , pp. e56458
    • Zhang, L.1    Ma, D.J.2    Zhang, Y.N.3    He, W.Z.4    Yang, J.J.5    Li, C.R.6    Jiang, H.Y.7
  • 114
    • 80755156037 scopus 로고    scopus 로고
    • Synthesis of novel derivatives of camptothecin as potential insecticides
    • Liu YQ, Yang L, Zhao YL, Li HY. Synthesis of novel derivatives of camptothecin as potential insecticides. Pest Biochem Physiol 2010;98:219-223.
    • (2010) Pest Biochem Physiol , vol.98 , pp. 219-223
    • Liu, Y.Q.1    Yang, L.2    Zhao, Y.L.3    Li, H.Y.4
  • 115
    • 80755153652 scopus 로고    scopus 로고
    • Synthesis and insecticidal activities of novel spin-labeled derivatives of camptothecin
    • Liu YQ, Dai W, Tian J. Synthesis and insecticidal activities of novel spin-labeled derivatives of camptothecin. Heteroatom Chem 2011;22:687-691.
    • (2011) Heteroatom Chem , vol.22 , pp. 687-691
    • Liu, Y.Q.1    Dai, W.2    Tian, J.3
  • 116
    • 84930612367 scopus 로고    scopus 로고
    • Structure-insecticide activity relationship on camptothecin derivants. Master's dissertation, Zhejiang A&F University
    • Zhang SY. Structure-insecticide activity relationship on camptothecin derivants. Master's dissertation, Zhejiang A&F University, 2011.
    • (2011)
    • Zhang, S.Y.1
  • 117
    • 84930583131 scopus 로고    scopus 로고
    • Nematocidal activity against pine wood nematode (Bursaphelenchus xylophilus) of 7-C-substituted 20-(S)-camptothecins
    • Zhang SY, Chen AL, Zhang LQ. Nematocidal activity against pine wood nematode (Bursaphelenchus xylophilus) of 7-C-substituted 20-(S)-camptothecins. Chin J Pestic Sci 2011;13:127-132.
    • (2011) Chin J Pestic Sci , vol.13 , pp. 127-132
    • Zhang, S.Y.1    Chen, A.L.2    Zhang, L.Q.3
  • 118
    • 84867024174 scopus 로고    scopus 로고
    • Antifeedant activity of camptothecin and its semisynthetic derivatives against Spodoptera litura (Fabricius) (Lepidoptera:Noctuidae) larvae
    • Li WQ, Liu YQ, Zhao YL, Zhou XW, Yang L, Feng G, Kou L. Antifeedant activity of camptothecin and its semisynthetic derivatives against Spodoptera litura (Fabricius) (Lepidoptera:Noctuidae) larvae. Curr Bioact Compd 2012;8:291-295.
    • (2012) Curr Bioact Compd , vol.8 , pp. 291-295
    • Li, W.Q.1    Liu, Y.Q.2    Zhao, Y.L.3    Zhou, X.W.4    Yang, L.5    Feng, G.6    Kou, L.7
  • 119
    • 84930612368 scopus 로고    scopus 로고
    • Utilizing camptotheca products for termite control. US 2002/0018762 Al.
    • Li SY, Nacogdoches TX. Utilizing camptotheca products for termite control. US 2002/0018762 Al.
    • Li, S.Y.1    Nacogdoches, T.X.2
  • 121
    • 18844479929 scopus 로고    scopus 로고
    • Effect of camptothecin, a topoisomerase I inhibitor on Plasmodium falciparum
    • Bodley AL, Cumming JN, Shapiro TA. Effect of camptothecin, a topoisomerase I inhibitor on Plasmodium falciparum. Biochem Pharmacol 1998;55:709-711.
    • (1998) Biochem Pharmacol , vol.55 , pp. 709-711
    • Bodley, A.L.1    Cumming, J.N.2    Shapiro, T.A.3
  • 122
    • 0029008048 scopus 로고
    • Molecular and cytotoxic effects of camptothecin, a topoisomerase I inhibitor, on trypanosomes and Leishmania
    • Bodley AL, Shapiro TA. Molecular and cytotoxic effects of camptothecin, a topoisomerase I inhibitor, on trypanosomes and Leishmania. Proc Natl Acad Sci USA 1995;92:3726-3730.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3726-3730
    • Bodley, A.L.1    Shapiro, T.A.2
  • 123
    • 0028818612 scopus 로고
    • Antitrypanosomal activity of camptothecin analogs. structure-activity correlations
    • Bodley AL, Wani MC, Wall ME, Shapiro TA. Antitrypanosomal activity of camptothecin analogs. structure-activity correlations. Biochem Pharmacol 1995;50:937-942.
    • (1995) Biochem Pharmacol , vol.50 , pp. 937-942
    • Bodley, A.L.1    Wani, M.C.2    Wall, M.E.3    Shapiro, T.A.4
  • 124
    • 0033917401 scopus 로고    scopus 로고
    • Analysis of stereoelectronic properties of camptothecin analogues in relation to biological activity
    • Werbovetz KA, Bhattacharjee AK, Brendle JJ, Scovill JP. Analysis of stereoelectronic properties of camptothecin analogues in relation to biological activity. Bioorg Med Chem 2000;8:1741-1747.
    • (2000) Bioorg Med Chem , vol.8 , pp. 1741-1747
    • Werbovetz, K.A.1    Bhattacharjee, A.K.2    Brendle, J.J.3    Scovill, J.P.4
  • 126
    • 0016749008 scopus 로고
    • Effect of topical use of camptothecine-dimethyl sulfoxide solution in psoriasis
    • Chiao C, Li H. Effect of topical use of camptothecine-dimethyl sulfoxide solution in psoriasis. Chin Med J (Engl) 1975;1:355-360.
    • (1975) Chin Med J (Engl) , vol.1 , pp. 355-360
    • Chiao, C.1    Li, H.2
  • 127
    • 84930612369 scopus 로고
    • Department of Dermatology, 1st Hospital, Beijing Medical College. Chemotherapy for psoriasis
    • Psoriasis Research Group. Department of Dermatology, 1st Hospital, Beijing Medical College. Chemotherapy for psoriasis. Chin J Dermatol 1980;13:61-63.
    • (1980) Chin J Dermatol , vol.13 , pp. 61-63
  • 128
    • 0023064710 scopus 로고
    • The effect of camptothecine in treating psoriasis
    • Lin XR, Huang T, Yang CM. The effect of camptothecine in treating psoriasis. Natl Med J China 1987;67:4-6.
    • (1987) Natl Med J China , vol.67 , pp. 4-6
    • Lin, X.R.1    Huang, T.2    Yang, C.M.3
  • 129
    • 0023681604 scopus 로고
    • Topical camptothecine in treatment of psoriasis
    • Lin XR, Huang T. Topical camptothecine in treatment of psoriasis. Int J Dermatol 1988;27:475-476.
    • (1988) Int J Dermatol , vol.27 , pp. 475-476
    • Lin, X.R.1    Huang, T.2
  • 130
    • 84930589728 scopus 로고    scopus 로고
    • Clinical observation of 10-hydroxycamptothecin on treatment of psoriasis
    • Wang XB, Luo L, Zeng J. Clinical observation of 10-hydroxycamptothecin on treatment of psoriasis. J Dermatol Venereol 2001;1:30-31.
    • (2001) J Dermatol Venereol , vol.1 , pp. 30-31
    • Wang, X.B.1    Luo, L.2    Zeng, J.3
  • 131
    • 0031706064 scopus 로고    scopus 로고
    • Camptothecin induces differentiation, tissue transglutaminase and apoptosis in cultured keratinocytes
    • Lin XR, Wilkinson DI, Farber EM. Camptothecin induces differentiation, tissue transglutaminase and apoptosis in cultured keratinocytes. Exp Dermatol 1998;7:179-183.
    • (1998) Exp Dermatol , vol.7 , pp. 179-183
    • Lin, X.R.1    Wilkinson, D.I.2    Farber, E.M.3
  • 132
    • 0033019511 scopus 로고    scopus 로고
    • Experimental studies on topoisomerase inhibitor camptothecin as an antipsoriatic agent
    • Lin XR, Wilkinson DI, Huang T, Farber EM. Experimental studies on topoisomerase inhibitor camptothecin as an antipsoriatic agent. Chin Med J (Engl) 1999;112:504-508.
    • (1999) Chin Med J (Engl) , vol.112 , pp. 504-508
    • Lin, X.R.1    Wilkinson, D.I.2    Huang, T.3    Farber, E.M.4
  • 133
    • 43449090712 scopus 로고    scopus 로고
    • Effects of isocamptothecin, a novel camptothecin analogue, on proliferation, apoptosis and telomerase activity in HaCaT cells
    • Lin JR, Liu XM, Bao YM, Hou SC, An LJ, Lin XR. Effects of isocamptothecin, a novel camptothecin analogue, on proliferation, apoptosis and telomerase activity in HaCaT cells. Exp Dermatol 2008;17:530-536.
    • (2008) Exp Dermatol , vol.17 , pp. 530-536
    • Lin, J.R.1    Liu, X.M.2    Bao, Y.M.3    Hou, S.C.4    An, L.J.5    Lin, X.R.6
  • 134
    • 33746933831 scopus 로고    scopus 로고
    • Camptothecin-mediated apoptosis and antiproliferation effect is accompanied by down-regulation of telomerase activity in HaCaT cells
    • Liu X, Lin J, Bao Y, Lin X, An L. Camptothecin-mediated apoptosis and antiproliferation effect is accompanied by down-regulation of telomerase activity in HaCaT cells. J Dermatol Sci 2006;42:262-264.
    • (2006) J Dermatol Sci , vol.42 , pp. 262-264
    • Liu, X.1    Lin, J.2    Bao, Y.3    Lin, X.4    An, L.5
  • 136
    • 11244352089 scopus 로고    scopus 로고
    • Antifungal activity of camptothecin, trifolin, and hyperoside isolated from Camptotheca acuminata
    • Li SY, Zhang ZZ, Cain AG, Wang B, Long M, Taylor J. Antifungal activity of camptothecin, trifolin, and hyperoside isolated from Camptotheca acuminata. J Agric Food Chem 2005;53:32-37.
    • (2005) J Agric Food Chem , vol.53 , pp. 32-37
    • Li, S.Y.1    Zhang, Z.Z.2    Cain, A.G.3    Wang, B.4    Long, M.5    Taylor, J.6
  • 137
    • 80555141744 scopus 로고    scopus 로고
    • Antifungal activity of camptothecin on Rhizoctonia solani, Sphaerotheca fuliginea and Pseudoperonospora cubensis
    • Zhang LQ, Sun YZ, Wang PW, Tong SM, Ma LJ. Antifungal activity of camptothecin on Rhizoctonia solani, Sphaerotheca fuliginea and Pseudoperonospora cubensis. J Zhejiang Forestry College 2008;25:681-684.
    • (2008) J Zhejiang Forestry College , vol.25 , pp. 681-684
    • Zhang, L.Q.1    Sun, Y.Z.2    Wang, P.W.3    Tong, S.M.4    Ma, L.J.5
  • 138
    • 84862168804 scopus 로고    scopus 로고
    • A. Synthesis, spectroscopic, and antimicrobial activity studies of novel 10-substituted camptothecin phosphorothioate analogs
    • Alaghaz ANMA, El-Sayad BA, Salwa AHA. Synthesis, spectroscopic, and antimicrobial activity studies of novel 10-substituted camptothecin phosphorothioate analogs. Phosphorus Sulfur Silicon Relat Elem 2012;187:799-807.
    • (2012) Phosphorus Sulfur Silicon Relat Elem , vol.187 , pp. 799-807
    • Alaghaz, A.N.M.A.1    El-Sayad, B.A.2    Salwa, A.H.3
  • 140
    • 1242271198 scopus 로고    scopus 로고
    • Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications
    • Rapisarda A, Uranchimeg B, Sordet O, Pommier Y, Shoemaker RH, Melillo G. Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications. Cancer Res 2004;64:1475-1482.
    • (2004) Cancer Res , vol.64 , pp. 1475-1482
    • Rapisarda, A.1    Uranchimeg, B.2    Sordet, O.3    Pommier, Y.4    Shoemaker, R.H.5    Melillo, G.6
  • 142
    • 3843078830 scopus 로고    scopus 로고
    • Targeting topoisomerase I to inhibit hypoxia inducible factor 1
    • Rapisarda A, Shoemaker RH, Melillo G. Targeting topoisomerase I to inhibit hypoxia inducible factor 1. Cell Cycle 2004;3:172-175.
    • (2004) Cell Cycle , vol.3 , pp. 172-175
    • Rapisarda, A.1    Shoemaker, R.H.2    Melillo, G.3
  • 143
    • 33750529529 scopus 로고    scopus 로고
    • Microwave expedited synthesis of 5-aminocamptothecin analogs: Inhibitors of hypoxia inducible factor HIF-1a
    • Torregrossa J, Bubley GJ, Jones GB. Microwave expedited synthesis of 5-aminocamptothecin analogs: Inhibitors of hypoxia inducible factor HIF-1a. Bioorg Med Chem Lett 2006;16:6082-6085.
    • (2006) Bioorg Med Chem Lett , vol.16 , pp. 6082-6085
    • Torregrossa, J.1    Bubley, G.J.2    Jones, G.B.3
  • 147
    • 34247121070 scopus 로고    scopus 로고
    • The camptothecin derivative CPT-11 inhibits angiogenesis in a dual-color imageable orthotopic metastatic nude mouse model of human colon cancer
    • Ji Y, Hayashi K, Amoh Y, Tsuji K, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, Hoffman RM. The camptothecin derivative CPT-11 inhibits angiogenesis in a dual-color imageable orthotopic metastatic nude mouse model of human colon cancer. Anticancer Res 2007;27:713-718.
    • (2007) Anticancer Res , vol.27 , pp. 713-718
    • Ji, Y.1    Hayashi, K.2    Amoh, Y.3    Tsuji, K.4    Yamauchi, K.5    Yamamoto, N.6    Tsuchiya, H.7    Tomita, K.8    Bouvet, M.9    Hoffman, R.M.10
  • 148
    • 0034844460 scopus 로고    scopus 로고
    • The inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in fibroblasts from patients with systemic sclerosis
    • Czuwara-Ladykowska J, Makiela B, Smith EA, Trojanowska M, Rudnicka L. The inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in fibroblasts from patients with systemic sclerosis. Arthritis Res 2001;3:311-318.
    • (2001) Arthritis Res , vol.3 , pp. 311-318
    • Czuwara-Ladykowska, J.1    Makiela, B.2    Smith, E.A.3    Trojanowska, M.4    Rudnicka, L.5
  • 149
    • 0037285988 scopus 로고    scopus 로고
    • The effect of inhibiting topoisomerase I and II on the anti-apoptotic response associated with pro-inflammatory crystals of calcium pyrophosphate dehydrate in human neutrophils
    • Tudan C, Jackson J, Higo TT, Burt HM. The effect of inhibiting topoisomerase I and II on the anti-apoptotic response associated with pro-inflammatory crystals of calcium pyrophosphate dehydrate in human neutrophils. Inflamm Res 2003;52:8-17.
    • (2003) Inflamm Res , vol.52 , pp. 8-17
    • Tudan, C.1    Jackson, J.2    Higo, T.T.3    Burt, H.M.4
  • 150
  • 151
    • 0035674850 scopus 로고    scopus 로고
    • Acetylcholinesterase blockade does not account for the adverse cardiovascular effects of the antitumor drug irinotecan: A preclinical study
    • Blandizzi C, de Paolis B, Colucci R, Paolo AD, Danesi R, del Tacca M. Acetylcholinesterase blockade does not account for the adverse cardiovascular effects of the antitumor drug irinotecan: A preclinical study. Toxicol Appl Pharmacol 2001;177:149-156.
    • (2001) Toxicol Appl Pharmacol , vol.177 , pp. 149-156
    • Blandizzi, C.1    de Paolis, B.2    Colucci, R.3    Paolo, A.D.4    Danesi, R.5    del Tacca, M.6
  • 152
    • 78049485082 scopus 로고    scopus 로고
    • Neurotoxic activity of a topoisomerase-I inhibitor, camptothecin, in cultured cerebellar granule neurons
    • Bhanu MU, Kondapi AK. Neurotoxic activity of a topoisomerase-I inhibitor, camptothecin, in cultured cerebellar granule neurons. Neurotoxicology 2010;31:730-737.
    • (2010) Neurotoxicology , vol.31 , pp. 730-737
    • Bhanu, M.U.1    Kondapi, A.K.2


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