S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in huntington's disease

Antioxidants and Redox Signaling

Volumn 19, Issue 11, 2013, Pages 1173-1184

  Haun, Florian ^a   Nakamura, Tomohiro ^a   Shiu, Alicia D ^a   Cho, Dong Hyung ^a   Tsunemi, Taiji ^b   Holland, Emily A ^a   La Spada, Albert R ^b,c   Lipton, Stuart A ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYNAMIN; DYNAMIN RELATED PROTEIN 1; HUNTINGTIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN TISSUE; CELL LOSS; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CORPUS STRIATUM; DENDRITIC SPINE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FEMALE; FLUORESCENCE; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; MALE; MITOCHONDRIAL DYNAMICS; MOUSE; MUTANT; NERVE CELL CULTURE; NERVE CELL LESION; NEUROTOXICITY; NITROSYLATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPSE;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BRAIN; CASE-CONTROL STUDIES; CORPUS STRIATUM; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; FEMALE; GTP PHOSPHOHYDROLASES; HUMANS; HUNTINGTON DISEASE; MALE; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; MUTANT PROTEINS; NERVE TISSUE PROTEINS; NEURONS; NITRIC OXIDE; PROTEIN BINDING; RATS;

EID: 84880940047     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2012.4928     Document Type: Article

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