Amelioration of rhabdomyolysis-induced renal mitochondrial injury and apoptosis through suppression of Drp-1 translocation

Journal of Nephrology

Volumn 26, Issue 6, 2013, Pages 1073-1082

  Tang, Wan Xin ^a   Wu, Wei Hua ^b   Qiu, Hong Yu ^a   Bo, Hong ^a   Huang, Song Min ^a  

^a SICHUAN UNIVERSITY   (China)

^b THE AFFILIATED HOSPITAL OF SOUTHWEST MEDICAL UNIVERSITY   (China)

Author keywords

Acute kidney injury; Apoptosis; Dynaminrelated protein 1; Mitochondria; Rhabdomyolysis

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 3; CYCLINE; CYTOCHROME C; DYNAMIN; DYNAMIN RELATED PROTEIN 1; MITOFUSIN 2; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; 3-(2,4-DICHLORO-5-METHOXYPHENYL)-2-SULFANYL-4(3H)-QUINAZOLINONE; CREATININE; DRP1 PROTEIN, RAT; GLYCEROL; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; MITOFUSIN 2 PROTEIN, RAT; MYOGLOBIN; QUINAZOLINONE DERIVATIVE; SOLVENT;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; ENZYME REPRESSION; KIDNEY FUNCTION; KIDNEY TUBULE CELL; MALE; MITOCHONDRION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; RHABDOMYOLYSIS; ACUTE KIDNEY INJURY; ANIMAL; BIOSYNTHESIS; BLOOD; CHEMICALLY INDUCED; COMPLICATION; CYTOSOL; DRUG EFFECTS; EPITHELIUM CELL; KIDNEY; KIDNEY TUBULE; METABOLISM; MITOCHONDRIAL DISEASES; MITOCHONDRIAL DYNAMICS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ACUTE KIDNEY INJURY; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CREATININE; CYTOCHROMES C; CYTOSOL; DYNAMINS; EPITHELIAL CELLS; GLYCEROL; KIDNEY; KIDNEY TUBULES; MALE; MEMBRANE PROTEINS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEINS; MYOGLOBIN; PROLIFERATING CELL NUCLEAR ANTIGEN; QUINAZOLINONES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RHABDOMYOLYSIS; SOLVENTS;

EID: 84889640326     PISSN: 11218428     EISSN: 17246059     Source Type: Journal    
DOI: 10.5301/jn.5000268     Document Type: Article

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