Mitochondrial division inhibitor-1 induces mitochondrial hyperfusion and sensitizes human cancer cells to TRAIL-induced apoptosis

International Journal of Oncology

Volumn 45, Issue 5, 2014, Pages 1901-1912

  Akita, Mamoru ^a,b   Suzuki Karasaki, Miki ^a   Fujiwara, Kyoko ^a   Nakagawa, Chinatsu ^a   Soma, Masayoshi ^a   Yoshida, Yukihiro ^b   Ochiai, Toyoko ^a   Tokuhashi, Yasuaki ^b   Suzuki Karasaki, Yoshihiro ^a,b  

^a NIHON UNIVERSITY   (Japan)

^b NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Mitochondrial division inhibitor 1; Mitochondrial fission; ROS; Tumor necrosis factor related apoptosis inducing ligand; Tumor selective killing

Indexed keywords

CARDIOLIPIN; CASPASE 12; CASPASE 3; CASPASE 7; DYNAMIN RELATED PROTEIN 1; MITOCHONDRIAL DIVISION INHIBITOR 1; MITOCHONDRIAL PROTEIN; PROTEIN INHIBITOR; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; DNM1L PROTEIN, HUMAN; GUANOSINE TRIPHOSPHATASE; MICROTUBULE ASSOCIATED PROTEIN; TNFSF10 PROTEIN, HUMAN;

A549 CELL LINE; APOPTOSIS; ARTICLE; CANCER CELL; CELL FUNCTION; CELL STRESS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FETUS; FLUORESCENCE IMAGING; GENE SILENCING; HUMAN; HUMAN CELL; MELANOMA CELL LINE; MITOCHONDRIAL HYPERFUSION; NORMAL HUMAN; OSTEOSARCOMA CELL LINE; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSITIZATION; ANIMAL; BIOSYNTHESIS; ENZYME ACTIVATION; GENETICS; MELANOMA; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE SILENCING; GTP PHOSPHOHYDROLASES; HUMANS; MELANOMA; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; REACTIVE OXYGEN SPECIES; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84907190373     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2014.2608     Document Type: Article

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