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Volumn 18, Issue 2, 2017, Pages 132-141

Infectious immunity in the central nervous system and brain function

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUID COMPARTMENT; BRAIN FUNCTION; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID; DEGENERATIVE DISEASE; HUMAN; IMMUNE RESPONSE; INFLAMMATION; MENTAL DISEASE; NONHUMAN; PRIORITY JOURNAL; REVIEW; ANIMAL; BRAIN; CENTRAL NERVOUS SYSTEM; IMMUNITY; IMMUNOLOGY; IMMUNOMODULATION; NEUROGENIC INFLAMMATION; NEUROLOGIC DISEASE; VIROLOGY; VIRUS INFECTION; VIRUS LOAD;

EID: 85009808678     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3656     Document Type: Review
Times cited : (160)

References (177)
  • 1
    • 13444269105 scopus 로고    scopus 로고
    • Host persistence: Exploitation of anti-inflammatory pathways by Toxoplasma gondii
    • Aliberti, J. Host persistence: exploitation of anti-inflammatory pathways by Toxoplasma gondii. Nat. Rev. Immunol. 5, 162-170 (2005).
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 162-170
    • Aliberti, J.1
  • 2
    • 84979995601 scopus 로고    scopus 로고
    • Neurological sequelae resulting from encephalitic alphavirus infection
    • Ronca, S.E., Dineley, K.T. & Paessler, S. Neurological sequelae resulting from encephalitic alphavirus infection. Front. Microbiol. 7, 959 (2016).
    • (2016) Front. Microbiol , vol.7 , pp. 959
    • Ronca, S.E.1    Dineley, K.T.2    Paessler, S.3
  • 3
    • 84937142611 scopus 로고    scopus 로고
    • Interleukin-1b receptor antagonism prevents cognitive impairment following experimental bacterial meningitis
    • Barichello, T. et al. Interleukin-1b receptor antagonism prevents cognitive impairment following experimental bacterial meningitis. Curr. Neurovasc. Res. 12, 253-261 (2015).
    • (2015) Curr. Neurovasc. Res , vol.12 , pp. 253-261
    • Barichello, T.1
  • 4
    • 78650780265 scopus 로고    scopus 로고
    • Long-Term sequelae of childhood bacterial meningitis: An underappreciated problem
    • Chandran, A., Herbert, H., Misurski, D. & Santosham, M. Long-Term sequelae of childhood bacterial meningitis: An underappreciated problem. Pediatr. Infect. Dis. J. 30, 3-6 (2011).
    • (2011) Pediatr. Infect. Dis. J , vol.30 , pp. 3-6
    • Chandran, A.1    Herbert, H.2    Misurski, D.3    Santosham, M.4
  • 6
    • 0028856131 scopus 로고
    • Adjunctive corticosteroid therapy in bacterial meningitis
    • Lauritsen, A. & Oberg, B. Adjunctive corticosteroid therapy in bacterial meningitis. Scand. J. Infect. Dis. 27, 431-434 (1995).
    • (1995) Scand. J. Infect. Dis , vol.27 , pp. 431-434
    • Lauritsen, A.1    Oberg, B.2
  • 7
    • 84964300304 scopus 로고    scopus 로고
    • Herpes simplex virus-1 encephalitis in adults: Pathophysiology, diagnosis, and management
    • Bradshaw, M.J. & Venkatesan, A. Herpes simplex virus-1 encephalitis in adults: pathophysiology, diagnosis, and management. Neurotherapeutics 13, 493-508 (2016).
    • (2016) Neurotherapeutics , vol.13 , pp. 493-508
    • Bradshaw, M.J.1    Venkatesan, A.2
  • 8
    • 84891705650 scopus 로고    scopus 로고
    • Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response
    • Clarke, P. et al. Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response. J. Virol. 88, 1080-1089 (2014).
    • (2014) J. Virol , vol.88 , pp. 1080-1089
    • Clarke, P.1
  • 9
    • 84968834217 scopus 로고    scopus 로고
    • A prospective study of magnetic resonance imaging patterns of central nervous system infections in pediatric age group and young adults and their clinico-biochemical correlation
    • Gupta, K., Banerjee, A., Saggar, K., Ahluwalia, A. & Saggar, K. A prospective study of magnetic resonance imaging patterns of central nervous system infections in pediatric age group and young adults and their clinico-biochemical correlation. J. Pediatr. Neurosci. 11, 46-51 (2016).
    • (2016) J. Pediatr. Neurosci , vol.11 , pp. 46-51
    • Gupta, K.1    Banerjee, A.2    Saggar, K.3    Ahluwalia, A.4    Saggar, K.5
  • 10
    • 30544447609 scopus 로고    scopus 로고
    • West Nile virus infection: MR imaging findings in the nervous system
    • Ali, M., Safriel, Y., Sohi, J., Llave, A. & Weathers, S. West Nile virus infection: MR imaging findings in the nervous system. AJNR Am. J. Neuroradiol. 26, 289-297 (2005).
    • (2005) AJNR Am. J. Neuroradiol , vol.26 , pp. 289-297
    • Ali, M.1    Safriel, Y.2    Sohi, J.3    Llave, A.4    Weathers, S.5
  • 11
    • 84863711523 scopus 로고    scopus 로고
    • 2-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and-independent mechanisms of host restriction in vivo
    • Szretter, K.J. et al. 2-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and-independent mechanisms of host restriction in vivo. PLoS Pathog. 8, e1002698 (2012).
    • (2012) PLoS Pathog , vol.8 , pp. e1002698
    • Szretter, K.J.1
  • 12
    • 84975691298 scopus 로고    scopus 로고
    • A complement-microglial axis drives synapse loss during virus-induced memory impairment
    • Vasek, M.J. et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature 534, 538-543 (2016).
    • (2016) Nature , vol.534 , pp. 538-543
    • Vasek, M.J.1
  • 13
    • 84888265891 scopus 로고    scopus 로고
    • Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: Case report
    • Leypoldt, F. et al. Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: case report. Neurology 81, 1637-1639 (2013).
    • (2013) Neurology , vol.81 , pp. 1637-1639
    • Leypoldt, F.1
  • 14
    • 77950956226 scopus 로고    scopus 로고
    • Changes in cerebrospinal fluid cytokine expression in tuberculous meningitis patients with treatment
    • Kashyap, R.S. et al. Changes in cerebrospinal fluid cytokine expression in tuberculous meningitis patients with treatment. Neuroimmunomodulation 17, 333-339 (2010).
    • (2010) Neuroimmunomodulation , vol.17 , pp. 333-339
    • Kashyap, R.S.1
  • 15
    • 84962418507 scopus 로고    scopus 로고
    • Complement and microglia mediate early synapse loss in Alzheimer mouse models
    • Hong, S. et al. Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science 352, 712-716 (2016).
    • (2016) Science , vol.352 , pp. 712-716
    • Hong, S.1
  • 16
    • 84901633386 scopus 로고    scopus 로고
    • Chemokines in the balance: Maintenance of homeostasis and protection at CNS barriers
    • Williams, J.L., Holman, D.W. & Klein, R.S. Chemokines in the balance: maintenance of homeostasis and protection at CNS barriers. Front. Cell. Neurosci. 8, 154 (2014).
    • (2014) Front. Cell. Neurosci , vol.8 , pp. 154
    • Williams, J.L.1    Holman, D.W.2    Klein, R.S.3
  • 17
    • 84936871460 scopus 로고    scopus 로고
    • Structural and functional features of central nervous system lymphatic vessels
    • Louveau, A. et al. Structural and functional features of central nervous system lymphatic vessels. Nature 523, 337-341 (2015).
    • (2015) Nature , vol.523 , pp. 337-341
    • Louveau, A.1
  • 18
    • 84865123660 scopus 로고    scopus 로고
    • A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid-b
    • Iliff, J.J. et al. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid-b. Sci. Transl. Med. 4, 147ra111 (2012).
    • (2012) Sci. Transl. Med , vol.4 , pp. 147ra111
    • Iliff, J.J.1
  • 19
    • 84923064724 scopus 로고    scopus 로고
    • Upon intranasal vesicular stomatitis virus infection, astrocytes in the olfactory bulb are important interferon-b producers that protect from lethal encephalitis
    • Detje, C.N. et al. Upon intranasal vesicular stomatitis virus infection, astrocytes in the olfactory bulb are important interferon-b producers that protect from lethal encephalitis. J. Virol. 89, 2731-2738 (2015).
    • (2015) J. Virol , vol.89 , pp. 2731-2738
    • Detje, C.N.1
  • 20
    • 38949145795 scopus 로고    scopus 로고
    • Induction of class i antigen processing components in oligodendroglia and microglia during viral encephalomyelitis
    • Malone, K.E., Stohlman, S.A., Ramakrishna, C., Macklin, W. & Bergmann, C.C. Induction of class I antigen processing components in oligodendroglia and microglia during viral encephalomyelitis. Glia 56, 426-435 (2008).
    • (2008) Glia , vol.56 , pp. 426-435
    • Malone, K.E.1    Stohlman, S.A.2    Ramakrishna, C.3    Macklin, W.4    Bergmann, C.C.5
  • 22
    • 84939606659 scopus 로고    scopus 로고
    • The choroid plexus-A multi-role player during infectious diseases of the CNS
    • Schwerk, C., Tenenbaum, T., Kim, K.S. & Schroten, H. The choroid plexus-A multi-role player during infectious diseases of the CNS. Front. Cell. Neurosci. 9, 80 (2015).
    • (2015) Front. Cell. Neurosci , vol.9 , pp. 80
    • Schwerk, C.1    Tenenbaum, T.2    Kim, K.S.3    Schroten, H.4
  • 23
    • 84959018667 scopus 로고    scopus 로고
    • Claudin-1,-2 and-3 are selectively expressed in the epithelia of the choroid plexus of the mouse from early development and into adulthood while claudin-5 is restricted to endothelial cells
    • Steinemann, A., Galm, I., Chip, S., Nitsch, C. & Maly, I.P. Claudin-1,-2 and-3 are selectively expressed in the epithelia of the choroid plexus of the mouse from early development and into adulthood while claudin-5 is restricted to endothelial cells. Front. Neuroanat. 10, 16 (2016).
    • (2016) Front. Neuroanat , vol.10 , pp. 16
    • Steinemann, A.1    Galm, I.2    Chip, S.3    Nitsch, C.4    Maly, I.P.5
  • 24
    • 0023153230 scopus 로고
    • Ultrastructure of the caudal portion of the fourth ventricular roof in the mouse
    • Oda, Y. & Nakanishi, I. Ultrastructure of the caudal portion of the fourth ventricular roof in the mouse. J. Comp. Neurol. 256, 299-307 (1987).
    • (1987) J. Comp. Neurol , vol.256 , pp. 299-307
    • Oda, Y.1    Nakanishi, I.2
  • 25
    • 53149095081 scopus 로고    scopus 로고
    • Ly-6G+CCR2-myeloid cells rather than Ly-6ChighCCR2+ monocytes are required for the control of bacterial infection in the central nervous system
    • Mildner, A. et al. Ly-6G+CCR2-myeloid cells rather than Ly-6ChighCCR2+ monocytes are required for the control of bacterial infection in the central nervous system. J. Immunol. 181, 2713-2722 (2008).
    • (2008) J. Immunol , vol.181 , pp. 2713-2722
    • Mildner, A.1
  • 26
    • 4544315971 scopus 로고    scopus 로고
    • Secreted proteins from Neisseria meningitidis mediate differential human gene expression and immune activation
    • Robinson, K., Taraktsoglou, M., Rowe, K.S., Wooldridge, K.G. & Ala'Aldeen, D.A. Secreted proteins from Neisseria meningitidis mediate differential human gene expression and immune activation. Cell. Microbiol. 6, 927-938 (2004).
    • (2004) Cell. Microbiol , vol.6 , pp. 927-938
    • Robinson, K.1    Taraktsoglou, M.2    Rowe, K.S.3    Wooldridge, K.G.4    Ala Aldeen, D.A.5
  • 27
    • 78651414195 scopus 로고    scopus 로고
    • Activation of brain endothelium by pneumococcal neuraminidase NanA promotes bacterial internalization
    • Banerjee, A. et al. Activation of brain endothelium by pneumococcal neuraminidase NanA promotes bacterial internalization. Cell. Microbiol. 12, 1576-1588 (2010).
    • (2010) Cell. Microbiol , vol.12 , pp. 1576-1588
    • Banerjee, A.1
  • 28
    • 0021151034 scopus 로고
    • Complement (C5)-derived chemotactic activity accounts for accumulation of polymorphonuclear leukocytes in cerebrospinal fluid of rabbits with pneumococcal meningitis
    • Ernst, J.D., Hartiala, K.T., Goldstein, I.M. & Sande, M.A. Complement (C5)-derived chemotactic activity accounts for accumulation of polymorphonuclear leukocytes in cerebrospinal fluid of rabbits with pneumococcal meningitis. Infect. Immun. 46, 81-86 (1984).
    • (1984) Infect. Immun , vol.46 , pp. 81-86
    • Ernst, J.D.1    Hartiala, K.T.2    Goldstein, I.M.3    Sande, M.A.4
  • 29
    • 35148896954 scopus 로고    scopus 로고
    • Phagocyte-derived catecholamines enhance acute inflammatory injury
    • Flierl, M.A. et al. Phagocyte-derived catecholamines enhance acute inflammatory injury. Nature 449, 721-725 (2007).
    • (2007) Nature , vol.449 , pp. 721-725
    • Flierl, M.A.1
  • 30
    • 84979748471 scopus 로고    scopus 로고
    • An experimental study of the neurophysical mechanisms of photophobia induced by subarachnoid hemorrhage
    • Aydin, N. et al. An experimental study of the neurophysical mechanisms of photophobia induced by subarachnoid hemorrhage. Neurosci. Lett. 630, 93-100 (2016).
    • (2016) Neurosci. Lett , vol.630 , pp. 93-100
    • Aydin, N.1
  • 31
    • 84943581188 scopus 로고    scopus 로고
    • DNGR-1+ dendritic cells are located in meningeal membrane and choroid plexus of the noninjured brain
    • Quintana, E. et al. DNGR-1+ dendritic cells are located in meningeal membrane and choroid plexus of the noninjured brain. Glia 63, 2231-2248 (2015).
    • (2015) Glia , vol.63 , pp. 2231-2248
    • Quintana, E.1
  • 32
    • 84907494134 scopus 로고    scopus 로고
    • IL-1R1 signaling regulates CXCL12-mediated T cell localization and fate within the central nervous system during West Nile Virus encephalitis
    • Durrant, D.M., Daniels, B.P. & Klein, R.S. IL-1R1 signaling regulates CXCL12-mediated T cell localization and fate within the central nervous system during West Nile Virus encephalitis. J. Immunol. 193, 4095-4106 (2014).
    • (2014) J. Immunol , vol.193 , pp. 4095-4106
    • Durrant, D.M.1    Daniels, B.P.2    Klein, R.S.3
  • 33
    • 84920485258 scopus 로고    scopus 로고
    • CCR2-dependent dendritic cell accumulation in the central nervous system during early effector experimental autoimmune encephalomyelitis is essential for effector T cell restimulation in situ and disease progression
    • Clarkson, B.D. et al. CCR2-dependent dendritic cell accumulation in the central nervous system during early effector experimental autoimmune encephalomyelitis is essential for effector T cell restimulation in situ and disease progression. J. Immunol. 194, 531-541 (2015).
    • (2015) J. Immunol , vol.194 , pp. 531-541
    • Clarkson, B.D.1
  • 34
    • 84965187161 scopus 로고    scopus 로고
    • Relationship between severity of aseptic meningitis and cerebrospinal fluid cytokine levels
    • Hikita, N. et al. Relationship between severity of aseptic meningitis and cerebrospinal fluid cytokine levels. Osaka City Med. J. 61, 63-71 (2015).
    • (2015) Osaka City Med. J , vol.61 , pp. 63-71
    • Hikita, N.1
  • 35
    • 84929497862 scopus 로고    scopus 로고
    • Cerebrospinal fluid cytokine profiles predict risk of early mortality and immune reconstitution inflammatory syndrome in HIV-Associated cryptococcal meningitis
    • Jarvis, J.N. et al. Cerebrospinal fluid cytokine profiles predict risk of early mortality and immune reconstitution inflammatory syndrome in HIV-Associated cryptococcal meningitis. PLoS Pathog. 11, e1004754 (2015).
    • (2015) PLoS Pathog , vol.11 , pp. e1004754
    • Jarvis, J.N.1
  • 36
    • 20444379486 scopus 로고    scopus 로고
    • Two patients with cryptococcal meningitis and idiopathic CD4 lymphopenia: Defective cytokine production and reversal by recombinant interferon-g therapy
    • Netea, M.G. et al. Two patients with cryptococcal meningitis and idiopathic CD4 lymphopenia: defective cytokine production and reversal by recombinant interferon-g therapy. Clin. Infect. Dis. 39, e83-e87 (2004).
    • (2004) Clin. Infect. Dis , vol.39 , pp. e83-e87
    • Netea, M.G.1
  • 37
    • 84959020187 scopus 로고    scopus 로고
    • Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid
    • Schläger, C. et al. Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid. Nature 530, 349-353 (2016).
    • (2016) Nature , vol.530 , pp. 349-353
    • Schläger, C.1
  • 38
  • 39
    • 84920267379 scopus 로고    scopus 로고
    • Adjuvant granulocyte colony-stimulating factor therapy results in improved spatial learning and stimulates hippocampal neurogenesis in a mouse model of pneumococcal meningitis
    • Schmidt, A.K. et al. Adjuvant granulocyte colony-stimulating factor therapy results in improved spatial learning and stimulates hippocampal neurogenesis in a mouse model of pneumococcal meningitis. J. Neuropathol. Exp. Neurol. 74, 85-94 (2015).
    • (2015) J. Neuropathol. Exp. Neurol , vol.74 , pp. 85-94
    • Schmidt, A.K.1
  • 40
    • 84879524778 scopus 로고    scopus 로고
    • Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage
    • Wippel, C. et al. Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage. PLoS Pathog. 9, e1003380 (2013).
    • (2013) PLoS Pathog , vol.9 , pp. e1003380
    • Wippel, C.1
  • 41
    • 84885463512 scopus 로고    scopus 로고
    • Neuroprotective intervention by interferon-g blockade prevents CD8+ T cell-mediated dendrite and synapse loss
    • Kreutzfeldt, M. et al. Neuroprotective intervention by interferon-g blockade prevents CD8+ T cell-mediated dendrite and synapse loss. J. Exp. Med. 210, 2087-2103 (2013).
    • (2013) J. Exp. Med , vol.210 , pp. 2087-2103
    • Kreutzfeldt, M.1
  • 43
    • 84930385063 scopus 로고    scopus 로고
    • Bacterial induction of Snail1 contributes to blood-brain barrier disruption
    • Kim, B.J. et al. Bacterial induction of Snail1 contributes to blood-brain barrier disruption. J. Clin. Invest. 125, 2473-2483 (2015).
    • (2015) J. Clin. Invest , vol.125 , pp. 2473-2483
    • Kim, B.J.1
  • 44
    • 84908428514 scopus 로고    scopus 로고
    • Viral pathogen-Associated molecular patterns regulate blood-brain barrier integrity via competing innate cytokine signals
    • Daniels, B.P. et al. Viral pathogen-Associated molecular patterns regulate blood-brain barrier integrity via competing innate cytokine signals. MBio 5, e01476-e14 (2014).
    • (2014) MBio , vol.5 , pp. e01476-e014714
    • Daniels, B.P.1
  • 45
    • 84928659307 scopus 로고    scopus 로고
    • Interferon-l restricts West Nile virus neuroinvasion by tightening the blood-brain barrier
    • Lazear, H.M. et al. Interferon-l restricts West Nile virus neuroinvasion by tightening the blood-brain barrier. Sci. Transl. Med. 7, 284ra59 (2015).
    • (2015) Sci. Transl. Med , vol.7 , pp. 284ra59
    • Lazear, H.M.1
  • 46
    • 84882338751 scopus 로고    scopus 로고
    • Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors
    • Bhattacharyya, S. et al. Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors. Cell Host Microbe 14, 136-147 (2013).
    • (2013) Cell Host Microbe , vol.14 , pp. 136-147
    • Bhattacharyya, S.1
  • 47
    • 84946956225 scopus 로고    scopus 로고
    • The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity
    • Miner, J.J. et al. The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity. Nat. Med. 21, 1464-1472 (2015).
    • (2015) Nat. Med , vol.21 , pp. 1464-1472
    • Miner, J.J.1
  • 48
    • 84255194757 scopus 로고    scopus 로고
    • Resolving postoperative neuroinflammation and cognitive decline
    • Terrando, N. et al. Resolving postoperative neuroinflammation and cognitive decline. Ann. Neurol. 70, 986-995 (2011).
    • (2011) Ann. Neurol , vol.70 , pp. 986-995
    • Terrando, N.1
  • 49
    • 84893911408 scopus 로고    scopus 로고
    • Role of dopamine in the recruitment of immune cells to the nigro-striatal dopaminergic structures
    • Espinosa-Oliva, A.M. et al. Role of dopamine in the recruitment of immune cells to the nigro-striatal dopaminergic structures. Neurotoxicology 41, 89-101 (2014).
    • (2014) Neurotoxicology , vol.41 , pp. 89-101
    • Espinosa-Oliva, A.M.1
  • 50
    • 84931010152 scopus 로고    scopus 로고
    • TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice
    • Wen, J. et al. TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice. J. Autoimmun. 60, 40-50 (2015).
    • (2015) J. Autoimmun , vol.60 , pp. 40-50
    • Wen, J.1
  • 51
    • 84964330538 scopus 로고    scopus 로고
    • Brain endothelial-And epithelial-specific interferon receptor chain 1 drives virus-induced sickness behavior and cognitive impairment
    • Blank, T. et al. Brain endothelial-And epithelial-specific interferon receptor chain 1 drives virus-induced sickness behavior and cognitive impairment. Immunity 44, 901-912 (2016).
    • (2016) Immunity , vol.44 , pp. 901-912
    • Blank, T.1
  • 52
    • 84936768465 scopus 로고    scopus 로고
    • Innate immune interactions within the central nervous system modulate pathogenesis of viral infections
    • Nair, S. & Diamond, M.S. Innate immune interactions within the central nervous system modulate pathogenesis of viral infections. Curr. Opin. Immunol. 36, 47-53 (2015).
    • (2015) Curr. Opin. Immunol , vol.36 , pp. 47-53
    • Nair, S.1    Diamond, M.S.2
  • 53
    • 78149433845 scopus 로고    scopus 로고
    • Myelination and support of axonal integrity by glia
    • Nave, K.A. Myelination and support of axonal integrity by glia. Nature 468, 244-252 (2010).
    • (2010) Nature , vol.468 , pp. 244-252
    • Nave, K.A.1
  • 54
    • 78149449524 scopus 로고    scopus 로고
    • Regulation of synaptic connectivity by glia
    • Eroglu, C. & Barres, B.A. Regulation of synaptic connectivity by glia. Nature 468, 223-231 (2010).
    • (2010) Nature , vol.468 , pp. 223-231
    • Eroglu, C.1    Barres, B.A.2
  • 56
    • 84876933529 scopus 로고    scopus 로고
    • Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation
    • Bardehle, S. et al. Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation. Nat. Neurosci. 16, 580-586 (2013).
    • (2013) Nat. Neurosci , vol.16 , pp. 580-586
    • Bardehle, S.1
  • 57
    • 49849098249 scopus 로고    scopus 로고
    • Brain-region-specific astroglial responses in vitro after LPS exposure
    • Kipp, M. et al. Brain-region-specific astroglial responses in vitro after LPS exposure. J. Mol. Neurosci. 35, 235-243 (2008).
    • (2008) J. Mol. Neurosci , vol.35 , pp. 235-243
    • Kipp, M.1
  • 58
    • 0032127722 scopus 로고    scopus 로고
    • Cultured astrocytes express regional heterogeneity of the immunoreactive phenotype under basal conditions and after g-IFN induction
    • Morga, E., Faber, C. & Heuschling, P. Cultured astrocytes express regional heterogeneity of the immunoreactive phenotype under basal conditions and after g-IFN induction. J. Neuroimmunol. 87, 179-184 (1998).
    • (1998) J. Neuroimmunol , vol.87 , pp. 179-184
    • Morga, E.1    Faber, C.2    Heuschling, P.3
  • 59
    • 77950858350 scopus 로고    scopus 로고
    • Astrocytes modulate the chemokine network in a pathogen-specific manner
    • McKimmie, C.S. & Graham, G.J. Astrocytes modulate the chemokine network in a pathogen-specific manner. Biochem. Biophys. Res. Commun. 394, 1006-1011 (2010).
    • (2010) Biochem. Biophys. Res. Commun , vol.394 , pp. 1006-1011
    • McKimmie, C.S.1    Graham, G.J.2
  • 60
    • 34547306640 scopus 로고    scopus 로고
    • Glutamate release from astrocytes in physiological conditions and in neurodegenerative disorders characterized by neuroinflammation
    • Vesce, S., Rossi, D., Brambilla, L. & Volterra, A. Glutamate release from astrocytes in physiological conditions and in neurodegenerative disorders characterized by neuroinflammation. Int. Rev. Neurobiol. 82, 57-71 (2007).
    • (2007) Int. Rev. Neurobiol , vol.82 , pp. 57-71
    • Vesce, S.1    Rossi, D.2    Brambilla, L.3    Volterra, A.4
  • 61
    • 70349425672 scopus 로고    scopus 로고
    • Astrocytic dysfunction: Insights on the role in neurodegeneration
    • Rossi, D. & Volterra, A. Astrocytic dysfunction: insights on the role in neurodegeneration. Brain Res. Bull. 80, 224-232 (2009).
    • (2009) Brain Res. Bull , vol.80 , pp. 224-232
    • Rossi, D.1    Volterra, A.2
  • 62
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • Kawai, T. & Akira, S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11, 373-384 (2010).
    • (2010) Nat. Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 63
    • 84947968868 scopus 로고    scopus 로고
    • Microglia regulate hippocampal neurogenesis during chronic neurodegeneration
    • De Lucia, C. et al. Microglia regulate hippocampal neurogenesis during chronic neurodegeneration. Brain Behav. Immun. 55, 179-190 (2016).
    • (2016) Brain Behav. Immun , vol.55 , pp. 179-190
    • De Lucia, C.1
  • 64
    • 33749258893 scopus 로고    scopus 로고
    • Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice
    • Djukic, M. et al. Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice. Brain 129, 2394-2403 (2006).
    • (2006) Brain , vol.129 , pp. 2394-2403
    • Djukic, M.1
  • 65
    • 84864152036 scopus 로고    scopus 로고
    • IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
    • Wang, Y. et al. IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. Nat. Immunol. 13, 753-760 (2012).
    • (2012) Nat. Immunol , vol.13 , pp. 753-760
    • Wang, Y.1
  • 66
    • 84929657353 scopus 로고    scopus 로고
    • Roles of microglia in brain development, tissue maintenance and repair
    • Michell-Robinson, M.A. et al. Roles of microglia in brain development, tissue maintenance and repair. Brain 138, 1138-1159 (2015).
    • (2015) Brain , vol.138 , pp. 1138-1159
    • Michell-Robinson, M.A.1
  • 67
    • 84864669092 scopus 로고    scopus 로고
    • Neonatal rat microglia derived from different brain regions have distinct activation responses
    • Lai, A.Y., Dhami, K.S., Dibal, C.D. & Todd, K.G. Neonatal rat microglia derived from different brain regions have distinct activation responses. Neuron Glia Biol. 7, 5-16 (2011).
    • (2011) Neuron Glia Biol , vol.7 , pp. 5-16
    • Lai, A.Y.1    Dhami, K.S.2    Dibal, C.D.3    Todd, K.G.4
  • 68
    • 0141853761 scopus 로고    scopus 로고
    • Neuro-cognitive impairment following acquired central nervous system infections in childhood: A systematic review
    • Carter, J.A., Neville, B.G. & Newton, C.R. Neuro-cognitive impairment following acquired central nervous system infections in childhood: A systematic review. Brain Res. Brain Res. Rev. 43, 57-69 (2003).
    • (2003) Brain Res. Brain Res. Rev , vol.43 , pp. 57-69
    • Carter, J.A.1    Neville, B.G.2    Newton, C.R.3
  • 69
    • 0037477629 scopus 로고    scopus 로고
    • Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway
    • Lehnardt, S. et al. Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway. Proc. Natl. Acad. Sci. USA 100, 8514-8519 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8514-8519
    • Lehnardt, S.1
  • 70
    • 0036890739 scopus 로고    scopus 로고
    • Pathophysiology of bacterial meningitis: Mechanism(s) of neuronal injury
    • Scheld, W.M., Koedel, U., Nathan, B. & Pfister, H.W. Pathophysiology of bacterial meningitis: mechanism(s) of neuronal injury. J. Infect. Dis. 186 (suppl. 2), S225-S233 (2002).
    • (2002) J. Infect. Dis , vol.186 , pp. S225-S233
    • Scheld, W.M.1    Koedel, U.2    Nathan, B.3    Pfister, H.W.4
  • 71
    • 84930798517 scopus 로고    scopus 로고
    • Adult bacterial meningitis-A quality registry study: Earlier treatment and favourable outcome if initial management by infectious diseases physicians
    • Grindborg, O., Naucler, P., Sjölin, J. & Glimaker, M. Adult bacterial meningitis-A quality registry study: earlier treatment and favourable outcome if initial management by infectious diseases physicians. Clin. Microbiol. Infect. 21, 560-566 (2015).
    • (2015) Clin. Microbiol. Infect , vol.21 , pp. 560-566
    • Grindborg, O.1    Naucler, P.2    Sjölin, J.3    Glimaker, M.4
  • 72
    • 0035887775 scopus 로고    scopus 로고
    • Meningeal and perivascular macrophages of the central nervous system play a protective role during bacterial meningitis
    • Polfliet, M.M. et al. Meningeal and perivascular macrophages of the central nervous system play a protective role during bacterial meningitis. J. Immunol. 167, 4644-4650 (2001).
    • (2001) J. Immunol , vol.167 , pp. 4644-4650
    • Polfliet, M.M.1
  • 73
    • 77951950320 scopus 로고    scopus 로고
    • Mechanisms of injury in bacterial meningitis
    • Gerber, J. & Nau, R. Mechanisms of injury in bacterial meningitis. Curr. Opin. Neurol. 23, 312-318 (2010).
    • (2010) Curr. Opin. Neurol , vol.23 , pp. 312-318
    • Gerber, J.1    Nau, R.2
  • 74
    • 0032977353 scopus 로고    scopus 로고
    • Neuroprotection by a caspase inhibitor in acute bacterial meningitis
    • Braun, J.S. et al. Neuroprotection by a caspase inhibitor in acute bacterial meningitis. Nat. Med. 5, 298-302 (1999).
    • (1999) Nat. Med , vol.5 , pp. 298-302
    • Braun, J.S.1
  • 75
    • 84880958106 scopus 로고    scopus 로고
    • Inflammasome activation mediates inflammation and outcome in humans and mice with pneumococcal meningitis
    • Geldhoff, M. et al. Inflammasome activation mediates inflammation and outcome in humans and mice with pneumococcal meningitis. BMC Infect. Dis. 13, 358 (2013).
    • (2013) BMC Infect. Dis , vol.13 , pp. 358
    • Geldhoff, M.1
  • 76
    • 41049093474 scopus 로고    scopus 로고
    • Chest radiographic findings in neurotuberculosis without pulmonary signs and symptoms
    • Aurangzeb, S., Badshah, M. & Khan, R. S. Chest radiographic findings in neurotuberculosis without pulmonary signs and symptoms. J. Coll. Physici. 18, 27-30 (2008).
    • (2008) J. Coll. Physici , vol.18 , pp. 27-30
    • Aurangzeb, S.1    Badshah, M.2    Khan, R.S.3
  • 77
    • 79953757886 scopus 로고    scopus 로고
    • Central nervous system tuberculosis
    • Cherian, A. & Thomas, S.V. Central nervous system tuberculosis. Afr. Health Sci. 11, 116-127 (2011).
    • (2011) Afr. Health Sci , vol.11 , pp. 116-127
    • Cherian, A.1    Thomas, S.V.2
  • 79
    • 80051976960 scopus 로고    scopus 로고
    • Assessing the chronic neuropsychologic sequelae of human immunodeficiency virus-negative cryptococcal meningitis by using diffusion tensor imaging
    • Lu, C.H. et al. Assessing the chronic neuropsychologic sequelae of human immunodeficiency virus-negative cryptococcal meningitis by using diffusion tensor imaging. Am. J. Neuroradiol. 32, 1333-1339 (2011).
    • (2011) Am. J. Neuroradiol , vol.32 , pp. 1333-1339
    • Lu, C.H.1
  • 80
    • 65549117005 scopus 로고    scopus 로고
    • Cryptococcal meningitis misdiagnosed as Alzheimer's disease: Complete neurological and cognitive recovery with treatment
    • Hoffmann, M., Muniz, J., Carroll, E. & De Villasante, J. Cryptococcal meningitis misdiagnosed as Alzheimer's disease: complete neurological and cognitive recovery with treatment. J. Alzheimers Dis. 16, 517-520 (2009).
    • (2009) J. Alzheimers Dis , vol.16 , pp. 517-520
    • Hoffmann, M.1    Muniz, J.2    Carroll, E.3    De Villasante, J.4
  • 81
    • 84865280800 scopus 로고    scopus 로고
    • Comparison and temporal trends of three groups with cryptococcosis: HIV-infected, solid organ transplant, and HIV-negative/non-Transplant
    • Bratton, E.W. et al. Comparison and temporal trends of three groups with cryptococcosis: HIV-infected, solid organ transplant, and HIV-negative/non-Transplant. PLoS One 7, e43582 (2012).
    • (2012) PLoS One , vol.7 , pp. e43582
    • Bratton, E.W.1
  • 82
    • 0033018324 scopus 로고    scopus 로고
    • Tuberculosis of the central nervous system
    • Garg, R.K. Tuberculosis of the central nervous system. Postgrad. Med. J. 75, 133-140 (1999).
    • (1999) Postgrad. Med. J , vol.75 , pp. 133-140
    • Garg, R.K.1
  • 83
    • 0019365670 scopus 로고
    • CSF cells in tuberculous meningitis. Humoral and cellular immune response
    • Pelc, S. & De Maertelaere, E. CSF cells in tuberculous meningitis. Humoral and cellular immune response. J. Neurol. Sci. 49, 223-228 (1981).
    • (1981) J. Neurol. Sci , vol.49 , pp. 223-228
    • Pelc, S.1    De Maertelaere, E.2
  • 84
    • 84908508708 scopus 로고    scopus 로고
    • Kinetics of T-cell-based assays on cerebrospinal fluid and peripheral blood mononuclear cells in patients with tuberculous meningitis
    • Park, K.H. et al. Kinetics of T-cell-based assays on cerebrospinal fluid and peripheral blood mononuclear cells in patients with tuberculous meningitis. Korean J. Intern. Med. 29, 793-799 (2014).
    • (2014) Korean J. Intern. Med , vol.29 , pp. 793-799
    • Park, K.H.1
  • 85
    • 84877971981 scopus 로고    scopus 로고
    • The phenotype of the Cryptococcus-specific CD4+ memory T-cell response is associated with disease severity and outcome in HIV-Associated cryptococcal meningitis
    • Jarvis, J.N. et al. The phenotype of the Cryptococcus-specific CD4+ memory T-cell response is associated with disease severity and outcome in HIV-Associated cryptococcal meningitis. J. Infect. Dis. 207, 1817-1828 (2013).
    • (2013) J. Infect. Dis , vol.207 , pp. 1817-1828
    • Jarvis, J.N.1
  • 86
    • 84930346377 scopus 로고    scopus 로고
    • Paradoxical immune responses in non-HIV cryptococcal meningitis
    • Panackal, A.A. et al. Paradoxical immune responses in non-HIV cryptococcal meningitis. PLoS Pathog. 11, e1004884 (2015).
    • (2015) PLoS Pathog , vol.11 , pp. e1004884
    • Panackal, A.A.1
  • 87
    • 84874225589 scopus 로고    scopus 로고
    • IFN-g Production by amyloid b-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer's disease
    • Browne, T.C. et al. IFN-g Production by amyloid b-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer's disease. J. Immunol. 190, 2241-2251 (2013).
    • (2013) J. Immunol , vol.190 , pp. 2241-2251
    • Browne, T.C.1
  • 88
    • 84953252996 scopus 로고    scopus 로고
    • TLR4-Activated microglia require IFN-g to induce severe neuronal dysfunction and death in situ
    • Papageorgiou, I.E. et al. TLR4-Activated microglia require IFN-g to induce severe neuronal dysfunction and death in situ. Proc. Natl. Acad. Sci. USA 113, 212-217 (2016).
    • (2016) Proc. Natl. Acad. Sci. USA , vol.113 , pp. 212-217
    • Papageorgiou, I.E.1
  • 89
    • 84954204064 scopus 로고    scopus 로고
    • Microglial activity in people at ultra high risk of psychosis and in schizophrenia: An [11C]PBR28 PET brain imaging study
    • Bloomfield, P.S. et al. Microglial activity in people at ultra high risk of psychosis and in schizophrenia: An [11C]PBR28 PET brain imaging study. Am. J. Psychiatry 173, 44-52 (2016).
    • (2016) Am. J. Psychiatry , vol.173 , pp. 44-52
    • Bloomfield, P.S.1
  • 90
    • 84960873341 scopus 로고    scopus 로고
    • Breaching the barrier-The nuclear envelope in virus infection
    • Mettenleiter, T.C. Breaching the barrier-The nuclear envelope in virus infection. J. Mol. Biol. 428, 1949-1961 (2016).
    • (2016) J. Mol. Biol , vol.428 , pp. 1949-1961
    • Mettenleiter, T.C.1
  • 91
    • 78649445081 scopus 로고    scopus 로고
    • Causes of encephalitis and differences in their clinical presentations in England: A multicentre, population-based prospective study
    • Granerod, J. et al. Causes of encephalitis and differences in their clinical presentations in England: A multicentre, population-based prospective study. Lancet Infect. Dis. 10, 835-844 (2010).
    • (2010) Lancet Infect. Dis , vol.10 , pp. 835-844
    • Granerod, J.1
  • 92
    • 84969983653 scopus 로고    scopus 로고
    • Encephalitic arboviruses: Emergence, clinical presentation, and neuropathogenesis
    • Salimi, H., Cain, M.D. & Klein, R.S. Encephalitic arboviruses: emergence, clinical presentation, and neuropathogenesis. Neurotherapeutics 13, 514-534 (2016).
    • (2016) Neurotherapeutics , vol.13 , pp. 514-534
    • Salimi, H.1    Cain, M.D.2    Klein, R.S.3
  • 93
    • 40349116664 scopus 로고    scopus 로고
    • A global perspective on the epidemiology of West Nile virus
    • Kramer, L.D., Styer, L.M. & Ebel, G.D. A global perspective on the epidemiology of West Nile virus. Annu. Rev. Entomol. 53, 61-81 (2008).
    • (2008) Annu. Rev. Entomol , vol.53 , pp. 61-81
    • Kramer, L.D.1    Styer, L.M.2    Ebel, G.D.3
  • 94
    • 84929915478 scopus 로고    scopus 로고
    • Innate immunity against HIV-1 infection
    • Altfeld, M. & Gale, M. Jr. Innate immunity against HIV-1 infection. Nat. Immunol. 16, 554-562 (2015).
    • (2015) Nat. Immunol , vol.16 , pp. 554-562
    • Altfeld, M.1    Gale, M.2
  • 95
    • 84947425666 scopus 로고    scopus 로고
    • Autoimmune post-herpes simplex encephalitis of adults and teenagers
    • Armangue, T. et al. Autoimmune post-herpes simplex encephalitis of adults and teenagers. Neurology 85, 1736-1743 (2015).
    • (2015) Neurology , vol.85 , pp. 1736-1743
    • Armangue, T.1
  • 96
    • 84947592263 scopus 로고    scopus 로고
    • Global research priorities for infections that affect the nervous system
    • John, C.C. et al. Global research priorities for infections that affect the nervous system. Nature 527, S178-S186 (2015).
    • (2015) Nature , vol.527 , pp. S178-S186
    • John, C.C.1
  • 97
    • 84355167680 scopus 로고    scopus 로고
    • Herpes simplex encephalitis and management of acyclovir in encephalitis patients in France
    • Steering Committee and Investigators Group.
    • Stahl, J.P., Mailles, A., De Broucker, T., & Steering Committee and Investigators Group. Herpes simplex encephalitis and management of acyclovir in encephalitis patients in France. Epidemiol. Infect. 140, 372-381 (2012).
    • (2012) Epidemiol. Infect , vol.140 , pp. 372-381
    • Stahl, J.P.1    Mailles, A.2    De Broucker, T.3
  • 98
    • 84907033125 scopus 로고    scopus 로고
    • Evaluation of prolonged fatigue post-West Nile virus infection and association of fatigue with elevated antiviral and proinflammatory cytokines
    • Garcia, M.N. et al. Evaluation of prolonged fatigue post-West Nile virus infection and association of fatigue with elevated antiviral and proinflammatory cytokines. Viral Immunol. 27, 327-333 (2014).
    • (2014) Viral Immunol , vol.27 , pp. 327-333
    • Garcia, M.N.1
  • 99
    • 77951244098 scopus 로고    scopus 로고
    • Persistent neuropsychological impairment associated with West Nile virus infection
    • Sadek, J.R. et al. Persistent neuropsychological impairment associated with West Nile virus infection. J. Clin. Exp. Neuropsychol. 32, 81-87 (2010).
    • (2010) J. Clin. Exp. Neuropsychol , vol.32 , pp. 81-87
    • Sadek, J.R.1
  • 100
    • 84872057940 scopus 로고    scopus 로고
    • TREM2 variants in Alzheimer's disease
    • Guerreiro, R. et al. TREM2 variants in Alzheimer's disease. N. Engl. J. Med. 368, 117-127 (2013).
    • (2013) N. Engl. J. Med , vol.368 , pp. 117-127
    • Guerreiro, R.1
  • 101
    • 84945324691 scopus 로고    scopus 로고
    • Do glia drive synaptic and cognitive impairment in disease?
    • Chung, W.S., Welsh, C.A., Barres, B.A. & Stevens, B. Do glia drive synaptic and cognitive impairment in disease? Nat. Neurosci. 18, 1539-1545 (2015).
    • (2015) Nat. Neurosci , vol.18 , pp. 1539-1545
    • Chung, W.S.1    Welsh, C.A.2    Barres, B.A.3    Stevens, B.4
  • 102
    • 33646707490 scopus 로고    scopus 로고
    • Protective immune responses against West Nile virus are primed by distinct complement activation pathways
    • Mehlhop, E. & Diamond, M.S. Protective immune responses against West Nile virus are primed by distinct complement activation pathways. J. Exp. Med. 203, 1371-1381 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 1371-1381
    • Mehlhop, E.1    Diamond, M.S.2
  • 103
    • 84861427387 scopus 로고    scopus 로고
    • Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner
    • Schafer, D.P. et al. Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron 74, 691-705 (2012).
    • (2012) Neuron , vol.74 , pp. 691-705
    • Schafer, D.P.1
  • 104
    • 78649976052 scopus 로고    scopus 로고
    • Microglial interactions with synapses are modulated by visual experience
    • Tremblay, M.E., Lowery, R.L. & Majewska, A.K. Microglial interactions with synapses are modulated by visual experience. PLoS Biol. 8, e1000527 (2010).
    • (2010) PLoS Biol , vol.8 , pp. e1000527
    • Tremblay, M.E.1    Lowery, R.L.2    Majewska, A.K.3
  • 105
    • 0034213718 scopus 로고    scopus 로고
    • High-level neuronal expression of Ab 1-42 in wild-Type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
    • Mucke, L. et al. High-level neuronal expression of Ab 1-42 in wild-Type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J. Neurosci. 20, 4050-4058 (2000).
    • (2000) J. Neurosci , vol.20 , pp. 4050-4058
    • Mucke, L.1
  • 106
    • 84981263293 scopus 로고    scopus 로고
    • The clinical spectrum of sporadic and familial forms of frontotemporal dementia
    • Woollacott, I.O. & Rohrer, J.D. The clinical spectrum of sporadic and familial forms of frontotemporal dementia. J. Neurochem. 138 (suppl. 1), 6-31 (2016).
    • (2016) J. Neurochem , vol.138 , pp. 6-31
    • Woollacott, I.O.1    Rohrer, J.D.2
  • 107
    • 84963969178 scopus 로고    scopus 로고
    • Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation
    • Lui, H. et al. Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation. Cell 165, 921-935 (2016).
    • (2016) Cell , vol.165 , pp. 921-935
    • Lui, H.1
  • 108
    • 0021145262 scopus 로고
    • Acyclovir versus vidarabine in herpes simplex encephalitis. Randomised multicentre study in consecutive Swedish patients
    • Sköldenberg, B. et al. Acyclovir versus vidarabine in herpes simplex encephalitis. Randomised multicentre study in consecutive Swedish patients. Lancet 2, 707-711 (1984).
    • (1984) Lancet , vol.2 , pp. 707-711
    • Sköldenberg, B.1
  • 109
    • 84900305950 scopus 로고    scopus 로고
    • Herpes simplex virus encephalitis: Clinical manifestations, diagnosis and outcome in 106 adult patients
    • H.S.V.E.S. Group
    • Sili, U., Kaya, A., Mert, A. & H.S.V.E.S. Group. Herpes simplex virus encephalitis: clinical manifestations, diagnosis and outcome in 106 adult patients. J. Clin. Virol. 60, 112-118 (2014).
    • (2014) J. Clin. Virol , vol.60 , pp. 112-118
    • Sili, U.1    Kaya, A.2    Mert, A.3
  • 110
    • 0038796249 scopus 로고    scopus 로고
    • Herpes simplex encephalitis relapses in children: Differentiation of two neurologic entities
    • De Tiège, X. et al. Herpes simplex encephalitis relapses in children: differentiation of two neurologic entities. Neurology 61, 241-243 (2003).
    • (2003) Neurology , vol.61 , pp. 241-243
    • De Tiège, X.1
  • 112
    • 77951658372 scopus 로고    scopus 로고
    • Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis
    • Hughes, E.G. et al. Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis. J. Neurosci. 30, 5866-5875 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 5866-5875
    • Hughes, E.G.1
  • 113
    • 84940107600 scopus 로고    scopus 로고
    • Human N-methyl d-Aspartate receptor antibodies alter memory and behaviour in mice
    • Planagumà, J. et al. Human N-methyl d-Aspartate receptor antibodies alter memory and behaviour in mice. Brain 138, 94-109 (2015).
    • (2015) Brain , vol.138 , pp. 94-109
    • Planagumà, J.1
  • 114
    • 84860607133 scopus 로고    scopus 로고
    • Disrupted surface cross-Talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis
    • Mikasova, L. et al. Disrupted surface cross-Talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis. Brain 135, 1606-1621 (2012).
    • (2012) Brain , vol.135 , pp. 1606-1621
    • Mikasova, L.1
  • 115
    • 84960886296 scopus 로고    scopus 로고
    • A Systematic meta-Analysis of Toxoplasma gondii prevalence in food animals in the United States
    • Guo, M. et al. A Systematic meta-Analysis of Toxoplasma gondii prevalence in food animals in the united states. Foodborne Pathog. Dis. 13, 109-118 (2016).
    • (2016) Foodborne Pathog. Dis , vol.13 , pp. 109-118
    • Guo, M.1
  • 116
    • 84934948884 scopus 로고    scopus 로고
    • From the blood to the brain: Avenues of eukaryotic pathogen dissemination to the central nervous system
    • Ueno, N. & Lodoen, M.B. From the blood to the brain: Avenues of eukaryotic pathogen dissemination to the central nervous system. Curr. Opin. Microbiol. 26, 53-59 (2015).
    • (2015) Curr. Opin. Microbiol , vol.26 , pp. 53-59
    • Ueno, N.1    Lodoen, M.B.2
  • 117
    • 84896390775 scopus 로고    scopus 로고
    • Toxoplasma development-Turn the switch on or off?
    • White, M.W., Radke, J.R. & Radke, J.B. Toxoplasma development-Turn the switch on or off? Cell. Microbiol. 16, 466-472 (2014).
    • (2014) Cell. Microbiol , vol.16 , pp. 466-472
    • White, M.W.1    Radke, J.R.2    Radke, J.B.3
  • 118
    • 82555184857 scopus 로고    scopus 로고
    • Fatal attraction phenomenon in humans: Cat odour attractiveness increased for toxoplasma-infected men while decreased for infected women
    • Flegr, J., Lenochová, P., Hodný, Z. & Vondrová, M. Fatal attraction phenomenon in humans: cat odour attractiveness increased for toxoplasma-infected men while decreased for infected women. PLoS Negl. Trop. Dis. 5, e1389 (2011).
    • (2011) PLoS Negl. Trop. Dis , vol.5 , pp. e1389
    • Flegr, J.1    Lenochová, P.2    Hodný, Z.3    Vondrová, M.4
  • 119
    • 34547536252 scopus 로고    scopus 로고
    • Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors
    • Vyas, A., Kim, S.K., Giacomini, N., Boothroyd, J.C. & Sapolsky, R.M. Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors. Proc. Natl. Acad. Sci. USA 104, 6442-6447 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 6442-6447
    • Vyas, A.1    Kim, S.K.2    Giacomini, N.3    Boothroyd, J.C.4    Sapolsky, R.M.5
  • 120
    • 84958818482 scopus 로고    scopus 로고
    • Morbid attraction to leopard urine in Toxoplasma-infected chimpanzees
    • Poirotte, C. et al. Morbid attraction to leopard urine in Toxoplasma-infected chimpanzees. Curr. Biol. 26, R98-R99 (2016).
    • (2016) Curr. Biol , vol.26 , pp. R98-R99
    • Poirotte, C.1
  • 121
    • 84923064828 scopus 로고    scopus 로고
    • Persistence of Toxoplasma gondii in the central nervous system: A fine-Tuned balance between the parasite, the brain and the immune system
    • Blanchard, N., Dunay, I.R. & Schlöter, D. Persistence of Toxoplasma gondii in the central nervous system: A fine-Tuned balance between the parasite, the brain and the immune system. Parasite Immunol. 37, 150-158 (2015).
    • (2015) Parasite Immunol , vol.37 , pp. 150-158
    • Blanchard, N.1    Dunay, I.R.2    Schlöter, D.3
  • 122
    • 84929842056 scopus 로고    scopus 로고
    • Characteristics and critical function of CD8+ T cells in the Toxoplasma-infected brain
    • Landrith, T.A., Harris, T.H. & Wilson, E.H. Characteristics and critical function of CD8+ T cells in the Toxoplasma-infected brain. Semin. Immunopathol. 37, 261-270 (2015).
    • (2015) Semin. Immunopathol , vol.37 , pp. 261-270
    • Landrith, T.A.1    Harris, T.H.2    Wilson, E.H.3
  • 123
    • 84959486168 scopus 로고    scopus 로고
    • Neurons are the primary target cell for the brain-Tropic intracellular parasite Toxoplasma gondii
    • Cabral, C.M. et al. Neurons are the primary target cell for the brain-Tropic intracellular parasite Toxoplasma gondii. PLoS Pathog. 12, e1005447 (2016).
    • (2016) PLoS Pathog , vol.12 , pp. e1005447
    • Cabral, C.M.1
  • 124
    • 84978881216 scopus 로고    scopus 로고
    • GLT-1-dependent disruption of CNS glutamate homeostasis and neuronal function by the protozoan parasite Toxoplasma gondii
    • David, C.N. et al. GLT-1-dependent disruption of CNS glutamate homeostasis and neuronal function by the protozoan parasite Toxoplasma gondii. PLoS Pathog. 12, e1005643 (2016).
    • (2016) PLoS Pathog , vol.12 , pp. e1005643
    • David, C.N.1
  • 125
    • 84923060232 scopus 로고    scopus 로고
    • Toxoplasma gondii-induced neuronal alterations
    • Parlog, A., Schlöter, D. & Dunay, I.R. Toxoplasma gondii-induced neuronal alterations. Parasite Immunol. 37, 159-170 (2015).
    • (2015) Parasite Immunol , vol.37 , pp. 159-170
    • Parlog, A.1    Schlöter, D.2    Dunay, I.R.3
  • 126
    • 84884252417 scopus 로고    scopus 로고
    • Mice infected with low-virulence strains of Toxoplasma gondii lose their innate aversion to cat urine, even after extensive parasite clearance
    • Ingram, W.M., Goodrich, L.M., Robey, E.A. & Eisen, M.B. Mice infected with low-virulence strains of Toxoplasma gondii lose their innate aversion to cat urine, even after extensive parasite clearance. PLoS One 8, e75246 (2013).
    • (2013) PLoS One , vol.8 , pp. e75246
    • Ingram, W.M.1    Goodrich, L.M.2    Robey, E.A.3    Eisen, M.B.4
  • 127
    • 84958053669 scopus 로고    scopus 로고
    • Toxoplasma gondii infection promotes neuroinflammation through cytokine networks and induced hyperalgesia in BALB/c mice
    • Mahmoudvand, H. et al. Toxoplasma gondii infection promotes neuroinflammation through cytokine networks and induced hyperalgesia in BALB/c mice. Inflammation 39, 405-412 (2016).
    • (2016) Inflammation , vol.39 , pp. 405-412
    • Mahmoudvand, H.1
  • 128
    • 84930907738 scopus 로고    scopus 로고
    • Microglia-dependent alteration of glutamatergic synaptic transmission and plasticity in the hippocampus during peripheral inflammation
    • Riazi, K. et al. Microglia-dependent alteration of glutamatergic synaptic transmission and plasticity in the hippocampus during peripheral inflammation. J. Neurosci. 35, 4942-4952 (2015).
    • (2015) J. Neurosci , vol.35 , pp. 4942-4952
    • Riazi, K.1
  • 129
    • 84891373204 scopus 로고    scopus 로고
    • Sustained IL-1b expression impairs adult hippocampal neurogenesis independent of IL-1 signaling in nestin+ neural precursor cells
    • Wu, M.D., Montgomery, S.L., Rivera-Escalera, F., Olschowka, J.A. & O'Banion, M.K. Sustained IL-1b expression impairs adult hippocampal neurogenesis independent of IL-1 signaling in nestin+ neural precursor cells. Brain Behav. Immun. 32, 9-18 (2013).
    • (2013) Brain Behav. Immun , vol.32 , pp. 9-18
    • Wu, M.D.1    Montgomery, S.L.2    Rivera-Escalera, F.3    Olschowka, J.A.4    O'Banion, M.K.5
  • 130
    • 84883822247 scopus 로고    scopus 로고
    • A cytokine network involving brain-borne IL-1b, IL-1ra, IL-18, IL-6, and TNFa operates during long-Term potentiation and learning
    • del Rey, A., Balschun, D., Wetzel, W., Randolf, A. & Besedovsky, H.O. A cytokine network involving brain-borne IL-1b, IL-1ra, IL-18, IL-6, and TNFa operates during long-Term potentiation and learning. Brain Behav. Immun. 33, 15-23 (2013).
    • (2013) Brain Behav. Immun , vol.33 , pp. 15-23
    • Del Rey, A.1    Balschun, D.2    Wetzel, W.3    Randolf, A.4    Besedovsky, H.O.5
  • 131
    • 84859150067 scopus 로고    scopus 로고
    • NR4A gene expression is dynamically regulated in the ventral tegmental area dopamine neurons and is related to expression of dopamine neurotransmission genes
    • Eells, J.B., Wilcots, J., Sisk, S. & Guo-Ross, S.X. NR4A gene expression is dynamically regulated in the ventral tegmental area dopamine neurons and is related to expression of dopamine neurotransmission genes. J. Mol. Neurosci. 46, 545-553 (2012).
    • (2012) J. Mol. Neurosci , vol.46 , pp. 545-553
    • Eells, J.B.1    Wilcots, J.2    Sisk, S.3    Guo-Ross, S.X.4
  • 132
    • 33746916754 scopus 로고    scopus 로고
    • Translated mutation in the Nurr1 gene as a cause for Parkinson's disease
    • Grimes, D.A. et al. Translated mutation in the Nurr1 gene as a cause for Parkinson's disease. Mov. Disord. 21, 906-909 (2006).
    • (2006) Mov. Disord , vol.21 , pp. 906-909
    • Grimes, D.A.1
  • 133
    • 84867783536 scopus 로고    scopus 로고
    • Nur-related receptor 1 gene polymorphisms and alcohol dependence in Mexican Americans
    • Wei, Y.M., Du, Y.L., Nie, Y.Q., Li, Y.Y. & Wan, Y.J. Nur-related receptor 1 gene polymorphisms and alcohol dependence in Mexican Americans. World J. Gastroenterol. 18, 5276-5282 (2012).
    • (2012) World J. Gastroenterol , vol.18 , pp. 5276-5282
    • Wei, Y.M.1    Du, Y.L.2    Nie, Y.Q.3    Li, Y.Y.4    Wan, Y.J.5
  • 134
    • 84983036894 scopus 로고    scopus 로고
    • Nurr1 expression is modified by inflammation in microglia
    • Lallier, S.W., Graf, A.E., Waidyarante, G.R. & Rogers, L.K. Nurr1 expression is modified by inflammation in microglia. Neuroreport 27, 1120-1127 (2016).
    • (2016) Neuroreport , vol.27 , pp. 1120-1127
    • Lallier, S.W.1    Graf, A.E.2    Waidyarante, G.R.3    Rogers, L.K.4
  • 135
    • 84929486150 scopus 로고    scopus 로고
    • Chronic Toxoplasma gondii in Nurr1-null heterozygous mice exacerbates elevated open field activity
    • Eells, J.B. et al. Chronic Toxoplasma gondii in Nurr1-null heterozygous mice exacerbates elevated open field activity. PLoS One 10, e0119280 (2015).
    • (2015) PLoS One , vol.10 , pp. e0119280
    • Eells, J.B.1
  • 136
    • 84926621730 scopus 로고    scopus 로고
    • Cognitive deterioration among bipolar disorder patients infected by Toxoplasma gondii is correlated to interleukin 6 levels
    • Hamdani, N. et al. Cognitive deterioration among bipolar disorder patients infected by Toxoplasma gondii is correlated to interleukin 6 levels. J. Affect. Disord. 179, 161-166 (2015).
    • (2015) J. Affect. Disord , vol.179 , pp. 161-166
    • Hamdani, N.1
  • 137
    • 84943638074 scopus 로고    scopus 로고
    • Lack of neuronal IFN-b-IFNAR causes Lewy body-And Parkinson's disease-like dementia
    • Ejlerskov, P. et al. Lack of neuronal IFN-b-IFNAR causes Lewy body-And Parkinson's disease-like dementia. Cell 163, 324-339 (2015).
    • (2015) Cell , vol.163 , pp. 324-339
    • Ejlerskov, P.1
  • 138
    • 84978160816 scopus 로고    scopus 로고
    • Unexpected role of interferon-g in regulating neuronal connectivity and social behaviour
    • Filiano, A.J. et al. Unexpected role of interferon-g in regulating neuronal connectivity and social behaviour. Nature 535, 425-429 (2016).
    • (2016) Nature , vol.535 , pp. 425-429
    • Filiano, A.J.1
  • 139
    • 77952311924 scopus 로고    scopus 로고
    • Regulation of learning and memory by meningeal immunity: A key role for IL-4
    • Derecki, N.C. et al. Regulation of learning and memory by meningeal immunity: A key role for IL-4. J. Exp. Med. 207, 1067-1080 (2010).
    • (2010) J. Exp. Med , vol.207 , pp. 1067-1080
    • Derecki, N.C.1
  • 140
    • 78649573450 scopus 로고    scopus 로고
    • Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease
    • Jones, L. et al. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS One 5, e13950 (2010).
    • (2010) PLoS One , vol.5 , pp. e13950
    • Jones, L.1
  • 141
    • 84970948063 scopus 로고    scopus 로고
    • Amyloid-b peptide protects against microbial infection in mouse and worm models of Alzheimer's disease
    • Kumar, D.K. et al. Amyloid-b peptide protects against microbial infection in mouse and worm models of Alzheimer's disease. Sci. Transl. Med. 8, 340ra72 (2016).
    • (2016) Sci. Transl. Med , vol.8 , pp. 340ra72
    • Kumar, D.K.1
  • 142
    • 84961126184 scopus 로고    scopus 로고
    • Alpha-synuclein expression restricts RNA viral infections in the brain
    • Beatman, E.L. et al. Alpha-synuclein expression restricts RNA viral infections in the brain. J. Virol. 90, 2767-2782 (2015).
    • (2015) J. Virol , vol.90 , pp. 2767-2782
    • Beatman, E.L.1
  • 143
    • 84976433829 scopus 로고    scopus 로고
    • Role of the IL-1 pathway in dopaminergic neurodegeneration and decreased voluntary movement
    • Stojakovic, A. et al. Role of the IL-1 pathway in dopaminergic neurodegeneration and decreased voluntary movement. Mol. Neurobiol. http://dx.doi.org/10.1007/s12035-016-9988-x (2016).
    • (2016) Mol. Neurobiol
    • Stojakovic, A.1
  • 144
    • 84941236952 scopus 로고    scopus 로고
    • Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1b in the aged hippocampus
    • Prieto, G.A. et al. Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1b in the aged hippocampus. Proc. Natl. Acad. Sci. USA 112, E5078-E5087 (2015).
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. E5078-E5087
    • Prieto, G.A.1
  • 145
    • 84879664081 scopus 로고    scopus 로고
    • Microglial activation underlies cerebellar deficits produced by repeated cannabis exposure
    • Cutando, L. et al. Microglial activation underlies cerebellar deficits produced by repeated cannabis exposure. J. Clin. Invest. 123, 2816-2831 (2013).
    • (2013) J. Clin. Invest , vol.123 , pp. 2816-2831
    • Cutando, L.1
  • 146
    • 84920077661 scopus 로고    scopus 로고
    • TNF-A regulates miRNA targeting mitochondrial complex-I and induces cell death in dopaminergic cells
    • Prajapati, P. et al. TNF-A regulates miRNA targeting mitochondrial complex-I and induces cell death in dopaminergic cells. Biochim. Biophys. Acta 1852, 451-461 (2015).
    • (2015) Biochim. Biophys. Acta , vol.1852 , pp. 451-461
    • Prajapati, P.1
  • 147
    • 84902862217 scopus 로고    scopus 로고
    • Upregulation of tumor necrosis factor-A in nucleus accumbens attenuates morphine-induced rewarding in a neuropathic pain model
    • Wu, Y. et al. Upregulation of tumor necrosis factor-A in nucleus accumbens attenuates morphine-induced rewarding in a neuropathic pain model. Biochem. Biophys. Res. Commun. 449, 502-507 (2014).
    • (2014) Biochem. Biophys. Res. Commun , vol.449 , pp. 502-507
    • Wu, Y.1
  • 148
    • 85009983223 scopus 로고    scopus 로고
    • The TNFa-Transgenic rat: Hippocampal synaptic integrity, cognition, function, and post-ischemic cell loss
    • Pettigrew, L.C., Kryscio, R.J. & Norris, C.M. The TNFa-Transgenic rat: hippocampal synaptic integrity, cognition, function, and post-ischemic cell loss. PLoS One 11, e0154721 (2016).
    • (2016) PLoS One , vol.11 , pp. e0154721
    • Pettigrew, L.C.1    Kryscio, R.J.2    Norris, C.M.3
  • 149
    • 33646199097 scopus 로고    scopus 로고
    • Synaptic scaling mediated by glial TNF-A
    • Stellwagen, D. & Malenka, R.C. Synaptic scaling mediated by glial TNF-A. Nature 440, 1054-1059 (2006).
    • (2006) Nature , vol.440 , pp. 1054-1059
    • Stellwagen, D.1    Malenka, R.C.2
  • 150
    • 84925598097 scopus 로고    scopus 로고
    • Tumor necrosis factor-A potentiates long-Term potentiation in the rat dentate gyrus after acute hypoxia
    • Wall, A.M., Mukandala, G., Greig, N.H. & O'Connor, J.J. Tumor necrosis factor-A potentiates long-Term potentiation in the rat dentate gyrus after acute hypoxia. J. Neurosci. Res. 93, 815-829 (2015).
    • (2015) J. Neurosci. Res , vol.93 , pp. 815-829
    • Wall, A.M.1    Mukandala, G.2    Greig, N.H.3    O'Connor, J.J.4
  • 151
    • 84876883238 scopus 로고    scopus 로고
    • Differential roles of TNFR1 and TNFR2 signaling in adult hippocampal neurogenesis
    • Chen, Z. & Palmer, T.D. Differential roles of TNFR1 and TNFR2 signaling in adult hippocampal neurogenesis. Brain Behav. Immun. 30, 45-53 (2013).
    • (2013) Brain Behav. Immun , vol.30 , pp. 45-53
    • Chen, Z.1    Palmer, T.D.2
  • 152
    • 84950288379 scopus 로고    scopus 로고
    • Neuroinflammatory TNFa impairs memory via astrocyte signaling
    • Habbas, S. et al. Neuroinflammatory TNFa impairs memory via astrocyte signaling. Cell 163, 1730-1741 (2015).
    • (2015) Cell , vol.163 , pp. 1730-1741
    • Habbas, S.1
  • 153
    • 84978105225 scopus 로고    scopus 로고
    • Microglia-derived cytokines/chemokines are involved in the enhancement of LPS-induced loss of nigrostriatal dopaminergic neurons in DJ-1 knockout mice
    • Chien, C.H., Lee, M.J., Liou, H.C., Liou, H.H. & Fu, W.M. Microglia-derived cytokines/chemokines are involved in the enhancement of LPS-induced loss of nigrostriatal dopaminergic neurons in DJ-1 knockout mice. PLoS One 11, e0151569 (2016).
    • (2016) PLoS One , vol.11 , pp. e0151569
    • Chien, C.H.1    Lee, M.J.2    Liou, H.C.3    Liou, H.H.4    Fu, W.M.5
  • 154
    • 1842687870 scopus 로고    scopus 로고
    • Acute exposure to CXC chemokine ligand 10, but not its chronic astroglial production, alters synaptic plasticity in mouse hippocampal slices
    • Vlkolinský, R., Siggins, G.R., Campbell, I.L. & Krucker, T. Acute exposure to CXC chemokine ligand 10, but not its chronic astroglial production, alters synaptic plasticity in mouse hippocampal slices. J. Neuroimmunol. 150, 37-47 (2004).
    • (2004) J. Neuroimmunol , vol.150 , pp. 37-47
    • Vlkolinský, R.1    Siggins, G.R.2    Campbell, I.L.3    Krucker, T.4
  • 155
    • 77954509661 scopus 로고    scopus 로고
    • Endogenous interferon-g directly regulates neural precursors in the noninflammatory brain
    • Li, L., Walker, T.L., Zhang, Y., Mackay, E.W. & Bartlett, P.F. Endogenous interferon-g directly regulates neural precursors in the noninflammatory brain. J. Neurosci. 30, 9038-9050 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 9038-9050
    • Li, L.1    Walker, T.L.2    Zhang, Y.3    Mackay, E.W.4    Bartlett, P.F.5
  • 156
    • 0030135421 scopus 로고    scopus 로고
    • Targeted CNS expression of interferon-g in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development
    • Corbin, J.G. et al. Targeted CNS expression of interferon-g in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development. Mol. Cell. Neurosci. 7, 354-370 (1996).
    • (1996) Mol. Cell. Neurosci , vol.7 , pp. 354-370
    • Corbin, J.G.1
  • 157
    • 84908609801 scopus 로고    scopus 로고
    • Insights from interferon-A-related depression for the pathogenesis of depression associated with inflammation
    • Hoyo-Becerra, C., Schlaak, J.F. & Hermann, D.M. Insights from interferon-A-related depression for the pathogenesis of depression associated with inflammation. Brain Behav. Immun. 42, 222-231 (2014).
    • (2014) Brain Behav. Immun , vol.42 , pp. 222-231
    • Hoyo-Becerra, C.1    Schlaak, J.F.2    Hermann, D.M.3
  • 158
    • 84904263852 scopus 로고    scopus 로고
    • Mechanisms for interferon-A-induced depression and neural stem cell dysfunction
    • Zheng, L.S. et al. Mechanisms for interferon-A-induced depression and neural stem cell dysfunction. Stem Cell Reports. 3, 73-84 (2014).
    • (2014) Stem Cell Reports , vol.3 , pp. 73-84
    • Zheng, L.S.1
  • 159
    • 39049134842 scopus 로고    scopus 로고
    • Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia
    • Yang, C.S. et al. Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia. J. Neuroinflammation 4, 27 (2007).
    • (2007) J. Neuroinflammation , vol.4 , pp. 27
    • Yang, C.S.1
  • 160
    • 0028929617 scopus 로고
    • Experimental pneumococcal meningitis: Cerebrovascular alterations, brain edema, and meningeal inflammation are linked to the production of nitric oxide
    • Koedel, U. et al. Experimental pneumococcal meningitis: cerebrovascular alterations, brain edema, and meningeal inflammation are linked to the production of nitric oxide. Ann. Neurol. 37, 313-323 (1995).
    • (1995) Ann. Neurol , vol.37 , pp. 313-323
    • Koedel, U.1
  • 161
    • 0035877050 scopus 로고    scopus 로고
    • Differential expression of nitric oxide synthases in bacterial meningitis: Role of the inducible isoform for blood-brain barrier breakdown
    • Winkler, F., Koedel, U., Kastenbauer, S. & Pfister, H.W. Differential expression of nitric oxide synthases in bacterial meningitis: role of the inducible isoform for blood-brain barrier breakdown. J. Infect. Dis. 183, 1749-1759 (2001).
    • (2001) J. Infect. Dis , vol.183 , pp. 1749-1759
    • Winkler, F.1    Koedel, U.2    Kastenbauer, S.3    Pfister, H.W.4
  • 162
    • 77952574671 scopus 로고    scopus 로고
    • NOD2 mediates inflammatory responses of primary murine glia to Streptococcus pneumoniae
    • Liu, X., Chauhan, V.S., Young, A.B. & Marriott, I. NOD2 mediates inflammatory responses of primary murine glia to Streptococcus pneumoniae. Glia 58, 839-847 (2010).
    • (2010) Glia , vol.58 , pp. 839-847
    • Liu, X.1    Chauhan, V.S.2    Young, A.B.3    Marriott, I.4
  • 163
    • 8744263879 scopus 로고    scopus 로고
    • Interaction of Neisseria meningitidis with human brain microvascular endothelial cells: Role of MAP-And tyrosine kinases in invasion and inflammatory cytokine release
    • Sokolova, O. et al. Interaction of Neisseria meningitidis with human brain microvascular endothelial cells: role of MAP-And tyrosine kinases in invasion and inflammatory cytokine release. Cell. Microbiol. 6, 1153-1166 (2004).
    • (2004) Cell. Microbiol , vol.6 , pp. 1153-1166
    • Sokolova, O.1
  • 164
    • 33846811142 scopus 로고    scopus 로고
    • Gene expression pattern in human brain endothelial cells in response to Neisseria meningitidis
    • Schubert-Unkmeir, A., Sokolova, O., Panzner, U., Eigenthaler, M. & Frosch, M. Gene expression pattern in human brain endothelial cells in response to Neisseria meningitidis. Infect. Immun. 75, 899-914 (2007).
    • (2007) Infect. Immun , vol.75 , pp. 899-914
    • Schubert-Unkmeir, A.1    Sokolova, O.2    Panzner, U.3    Eigenthaler, M.4    Frosch, M.5
  • 165
    • 84874395638 scopus 로고    scopus 로고
    • Transmigration of polymorphnuclear neutrophils and monocytes through the human blood-cerebrospinal fluid barrier after bacterial infection in vitro
    • Steinmann, U. et al. Transmigration of polymorphnuclear neutrophils and monocytes through the human blood-cerebrospinal fluid barrier after bacterial infection in vitro. J. Neuroinflammation 10, 31 (2013).
    • (2013) J. Neuroinflammation , vol.10 , pp. 31
    • Steinmann, U.1
  • 166
    • 84896317914 scopus 로고    scopus 로고
    • Astrocytes produce IL-19 in response to bacterial challenge and are sensitive to the immunosuppressive effects of this IL-10 family member
    • Cooley, I.D., Chauhan, V.S., Donneyz, M.A. & Marriott, I. Astrocytes produce IL-19 in response to bacterial challenge and are sensitive to the immunosuppressive effects of this IL-10 family member. Glia 62, 818-828 (2014).
    • (2014) Glia , vol.62 , pp. 818-828
    • Cooley, I.D.1    Chauhan, V.S.2    Donneyz, M.A.3    Marriott, I.4
  • 167
    • 0024358178 scopus 로고
    • Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response
    • Waage, A. et al. Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response. J. Exp. Med. 170, 1859-1867 (1989).
    • (1989) J. Exp. Med , vol.170 , pp. 1859-1867
    • Waage, A.1
  • 168
    • 84884214543 scopus 로고    scopus 로고
    • Cryptococcus neoformans promotes its transmigration into the central nervous system by inducing molecular and cellular changes in brain endothelial cells
    • Vu, K., Eigenheer, R.A., Phinney, B.S. & Gelli, A. Cryptococcus neoformans promotes its transmigration into the central nervous system by inducing molecular and cellular changes in brain endothelial cells. Infect. Immun. 81, 3139-3147 (2013).
    • (2013) Infect. Immun , vol.81 , pp. 3139-3147
    • Vu, K.1    Eigenheer, R.A.2    Phinney, B.S.3    Gelli, A.4
  • 169
    • 0028227204 scopus 로고
    • Human astrocytes inhibit Cryptococcus neoformans growth by a nitric oxide-mediated mechanism
    • Lee, S.C., Dickson, D.W., Brosnan, C.F. & Casadevall, A. Human astrocytes inhibit Cryptococcus neoformans growth by a nitric oxide-mediated mechanism. J. Exp. Med. 180, 365-369 (1994).
    • (1994) J. Exp. Med , vol.180 , pp. 365-369
    • Lee, S.C.1    Dickson, D.W.2    Brosnan, C.F.3    Casadevall, A.4
  • 170
    • 7044229558 scopus 로고    scopus 로고
    • Human endothelial cell activation and apoptosis induced by enterovirus 71 infection
    • Liang, C.C. et al. Human endothelial cell activation and apoptosis induced by enterovirus 71 infection. J. Med. Virol. 74, 597-603 (2004).
    • (2004) J. Med. Virol , vol.74 , pp. 597-603
    • Liang, C.C.1
  • 171
    • 84870476228 scopus 로고    scopus 로고
    • Chemotaxis of T-cells after infection of human choroid plexus papilloma cells with Echovirus 30 in an in vitro model of the blood-cerebrospinal fluid barrier
    • Schneider, H. et al. Chemotaxis of T-cells after infection of human choroid plexus papilloma cells with Echovirus 30 in an in vitro model of the blood-cerebrospinal fluid barrier. Virus Res. 170, 66-74 (2012).
    • (2012) Virus Res , vol.170 , pp. 66-74
    • Schneider, H.1
  • 172
    • 84944725031 scopus 로고    scopus 로고
    • Intrinsic apoptosis and proinflammatory cytokines regulated in human astrocytes infected with enterovirus 71
    • Wang, C. et al. Intrinsic apoptosis and proinflammatory cytokines regulated in human astrocytes infected with enterovirus 71. J. Gen. Virol. 96, 3010-3022 (2015).
    • (2015) J. Gen. Virol , vol.96 , pp. 3010-3022
    • Wang, C.1
  • 173
    • 84859716889 scopus 로고    scopus 로고
    • TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice
    • Reinert, L.S. et al. TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice. J. Clin. Invest. 122, 1368-1376 (2012).
    • (2012) J. Clin. Invest , vol.122 , pp. 1368-1376
    • Reinert, L.S.1
  • 174
    • 84882579199 scopus 로고    scopus 로고
    • HSV-1 activates NF-kB in mouse astrocytes and increases TNF-A and IL-6 expression via Toll-like receptor 3
    • Liu, Z. et al. HSV-1 activates NF-kB in mouse astrocytes and increases TNF-A and IL-6 expression via Toll-like receptor 3. Neurol. Res. 35, 755-762 (2013).
    • (2013) Neurol. Res , vol.35 , pp. 755-762
    • Liu, Z.1
  • 175
    • 77950663390 scopus 로고    scopus 로고
    • Regional heterogeneity and diversity in cytokine and chemokine production by astroglia: Differential responses to HIV-1 Tat, gp120, and morphine revealed by multiplex analysis
    • Fitting, S. et al. Regional heterogeneity and diversity in cytokine and chemokine production by astroglia: differential responses to HIV-1 Tat, gp120, and morphine revealed by multiplex analysis. J. Proteome Res. 9, 1795-1804 (2010).
    • (2010) J. Proteome Res , vol.9 , pp. 1795-1804
    • Fitting, S.1
  • 176
    • 33846106368 scopus 로고    scopus 로고
    • Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses
    • Wacher, C. et al. Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses. J. Virol. 81, 860-871 (2007).
    • (2007) J. Virol , vol.81 , pp. 860-871
    • Wacher, C.1
  • 177
    • 84877596501 scopus 로고    scopus 로고
    • Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses
    • Cho, H. et al. Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses. Nat. Med. 19, 458-464 (2013).
    • (2013) Nat. Med , vol.19 , pp. 458-464
    • Cho, H.1


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