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Volumn 12, Issue 11, 2010, Pages 1576-1588

Activation of brain endothelium by pneumococcal neuraminidase NanA promotes bacterial internalization

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; RECOMBINANT PROTEIN; SIALIDASE;

EID: 78651414195     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2010.01490.x     Document Type: Article
Times cited : (66)

References (52)
  • 1
    • 56749156007 scopus 로고    scopus 로고
    • Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases
    • Bernatoniene, J., Zhang, Q., Dogan, S., Mitchell, T.J., Paton, J.C., and Finn, A. (2008) Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases. J Infect Dis 198: 1823-1833.
    • (2008) J Infect Dis , vol.198 , pp. 1823-1833
    • Bernatoniene, J.1    Zhang, Q.2    Dogan, S.3    Mitchell, T.J.4    Paton, J.C.5    Finn, A.6
  • 2
    • 0024355265 scopus 로고
    • Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae
    • Berry, A.M., Yother, J., Briles, D.E., Hansman, D., and Paton, J.C. (1989) Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae. Infect Immun 57: 2037-2042.
    • (1989) Infect Immun , vol.57 , pp. 2037-2042
    • Berry, A.M.1    Yother, J.2    Briles, D.E.3    Hansman, D.4    Paton, J.C.5
  • 3
    • 0027007972 scopus 로고
    • An overview of the multiple functions of the blood-brain barrier
    • Betz, A.L. (1992) An overview of the multiple functions of the blood-brain barrier. NIDA Res Monogr 120: 54-72.
    • (1992) NIDA Res Monogr , vol.120 , pp. 54-72
    • Betz, A.L.1
  • 4
    • 0022559194 scopus 로고
    • Specialized properties and solute transport in brain capillaries
    • Betz, A.L., and Goldstein, G.W. (1986) Specialized properties and solute transport in brain capillaries. Annu Rev Physiol 48: 241-250.
    • (1986) Annu Rev Physiol , vol.48 , pp. 241-250
    • Betz, A.L.1    Goldstein, G.W.2
  • 5
    • 0020051148 scopus 로고
    • Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker
    • Bradley, P.P., Priebat, D.A., Christensen, R.D., and Rothstein, G. (1982) Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78: 206-209.
    • (1982) J Invest Dermatol , vol.78 , pp. 206-209
    • Bradley, P.P.1    Priebat, D.A.2    Christensen, R.D.3    Rothstein, G.4
  • 6
    • 0027999183 scopus 로고
    • A neuraminidase from Streptococcus pneumoniae has the features of a surface protein
    • Camara, M., Boulnois, G.J., Andrew, P.W., and Mitchell, T.J. (1994) A neuraminidase from Streptococcus pneumoniae has the features of a surface protein. Infect Immun 62: 3688-3695.
    • (1994) Infect Immun , vol.62 , pp. 3688-3695
    • Camara, M.1    Boulnois, G.J.2    Andrew, P.W.3    Mitchell, T.J.4
  • 8
    • 0029165459 scopus 로고
    • Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor
    • Cundell, D.R., Gerard, N.P., Gerard, C., Idanpaan-Heikkila, I., and Tuomanen, E.I. (1995) Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. Nature 377: 435-438.
    • (1995) Nature , vol.377 , pp. 435-438
    • Cundell, D.R.1    Gerard, N.P.2    Gerard, C.3    Idanpaan-Heikkila, I.4    Tuomanen, E.I.5
  • 10
    • 0141723665 scopus 로고    scopus 로고
    • Group B streptococcal beta hemolysin/cytolysin activates neutrophil signalling pathways in brain endothelium and contributes to developments of meningitis
    • Doran, K.S., Liu, G.Y., and Nizet, V. (2003) Group B streptococcal beta hemolysin/cytolysin activates neutrophil signalling pathways in brain endothelium and contributes to developments of meningitis. J Clin Invest 112: 736-744.
    • (2003) J Clin Invest , vol.112 , pp. 736-744
    • Doran, K.S.1    Liu, G.Y.2    Nizet, V.3
  • 11
    • 24644446476 scopus 로고    scopus 로고
    • Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid
    • Doran, K.S., Engelson, E.J., Khosravi, A., Maisey, H.C., Fedtke, I., Equils, O., etal. (2005) Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid. J Clin Invest 115: 2499-2507.
    • (2005) J Clin Invest , vol.115 , pp. 2499-2507
    • Doran, K.S.1    Engelson, E.J.2    Khosravi, A.3    Maisey, H.C.4    Fedtke, I.5    Equils, O.6
  • 13
    • 12444289493 scopus 로고    scopus 로고
    • Opposing roles of integrin alpha6beta1 and dystroglycan in laminin mediated extracellular signal regulated kinase activation
    • Ferletta, M., Kikkawa, Y., Yu, H., Talts, J.F., Durbeej, M., Sonnenberg, A., etal. (2003) Opposing roles of integrin alpha6beta1 and dystroglycan in laminin mediated extracellular signal regulated kinase activation. Mol Biol Cell 14: 2088-2103.
    • (2003) Mol Biol Cell , vol.14 , pp. 2088-2103
    • Ferletta, M.1    Kikkawa, Y.2    Yu, H.3    Talts, J.F.4    Durbeej, M.5    Sonnenberg, A.6
  • 14
    • 0037079004 scopus 로고    scopus 로고
    • Dexamethasone in Adults with Bacterial Meningitis
    • Gans, J.D., and Beek, D.V.D. (2002) Dexamethasone in Adults with Bacterial Meningitis. N Engl J Med 347: 1549-1556.
    • (2002) N Engl J Med , vol.347 , pp. 1549-1556
    • Gans, J.D.1    Beek, D.V.D.2
  • 15
    • 33845488909 scopus 로고    scopus 로고
    • Differential role of CbpA and PspA in modulation of in vitro CXC chemokine responses of respiratory epithelial cells to infection with Streptococcus pneumoniae
    • Graham, R.M., and Paton, J.C. (2006) Differential role of CbpA and PspA in modulation of in vitro CXC chemokine responses of respiratory epithelial cells to infection with Streptococcus pneumoniae. Infect Immun 74: 6739-6749.
    • (2006) Infect Immun , vol.74 , pp. 6739-6749
    • Graham, R.M.1    Paton, J.C.2
  • 16
    • 15644369239 scopus 로고    scopus 로고
    • Molecular cloning of a novel human CC chemokine liver and activation-regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2
    • Hieshima, K., Imai, T., Opdenakker, G., Damme, J.V., Kusuda, J., Tei, H., etal. (1997) Molecular cloning of a novel human CC chemokine liver and activation-regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2. J Biol Chem 272: 5846-5853.
    • (1997) J Biol Chem , vol.272 , pp. 5846-5853
    • Hieshima, K.1    Imai, T.2    Opdenakker, G.3    Damme, J.V.4    Kusuda, J.5    Tei, H.6
  • 18
    • 0014104556 scopus 로고
    • Neuraminidase activities of clinical isolates of Diplococcus pneumoniae
    • Kelly, R.T., Farmer, S., and Greiff, D. (1967) Neuraminidase activities of clinical isolates of Diplococcus pneumoniae. J Bacteriol 94: 272-273.
    • (1967) J Bacteriol , vol.94 , pp. 272-273
    • Kelly, R.T.1    Farmer, S.2    Greiff, D.3
  • 19
    • 0034873330 scopus 로고    scopus 로고
    • Escherichia coli translocation at the blood-brain barrier
    • Kim, K.S. (2001) Escherichia coli translocation at the blood-brain barrier. Infect Immun 69: 5217-5222.
    • (2001) Infect Immun , vol.69 , pp. 5217-5222
    • Kim, K.S.1
  • 20
    • 4744374116 scopus 로고    scopus 로고
    • Phase variable desialylation of host proteins that bind to Streptococcus pneumoniae in vivo and protect the airway
    • King, S.J., Hippe, K.R., Gould, J.M., Bae, D., Peterson, S., Cline, R.T., etal. (2004) Phase variable desialylation of host proteins that bind to Streptococcus pneumoniae in vivo and protect the airway. Mol Microbiol 54: 159-171.
    • (2004) Mol Microbiol , vol.54 , pp. 159-171
    • King, S.J.1    Hippe, K.R.2    Gould, J.M.3    Bae, D.4    Peterson, S.5    Cline, R.T.6
  • 21
    • 22544485354 scopus 로고    scopus 로고
    • NanA, a neuraminidase from Streptococcus pneumoniae, shows high levels of sequence diversity, at least in part through recombination with Streptococcus oralis
    • King, S.J., Whatmore, A.M., and Dowson, C.G. (2005) NanA, a neuraminidase from Streptococcus pneumoniae, shows high levels of sequence diversity, at least in part through recombination with Streptococcus oralis. J Bacteriol 187: 5376-5386.
    • (2005) J Bacteriol , vol.187 , pp. 5376-5386
    • King, S.J.1    Whatmore, A.M.2    Dowson, C.G.3
  • 22
    • 58549088321 scopus 로고    scopus 로고
    • Bacterial neuraminidase increases IL-8 production in lung epithelial cells via NF-kappaB-dependent pathway
    • Kuroiwa, A., Hisatsune, A., Isohama, Y., and Katsuki, H. (2009) Bacterial neuraminidase increases IL-8 production in lung epithelial cells via NF-kappaB-dependent pathway. Biochem Biophys Res Commun 379: 754-759.
    • (2009) Biochem Biophys Res Commun , vol.379 , pp. 754-759
    • Kuroiwa, A.1    Hisatsune, A.2    Isohama, Y.3    Katsuki, H.4
  • 23
    • 33745585810 scopus 로고    scopus 로고
    • Pneumococcal neuraminidases A and B both have essential roles during infection of the respiratory tract and sepsis
    • Manco, S., Hernon, F., Yesilkaya, H., Paton, J.C., Andrew, P.W., and Kadioglu, A. (2006) Pneumococcal neuraminidases A and B both have essential roles during infection of the respiratory tract and sepsis. Infect Immun 74: 4014-4020.
    • (2006) Infect Immun , vol.74 , pp. 4014-4020
    • Manco, S.1    Hernon, F.2    Yesilkaya, H.3    Paton, J.C.4    Andrew, P.W.5    Kadioglu, A.6
  • 24
    • 0036109016 scopus 로고    scopus 로고
    • Current concepts in the pathogenesis of meningitis caused by Streptococcus pneumoniae
    • Meli, D.N., Christen, S., Leib, S.L., and Tauber, M.G. (2002) Current concepts in the pathogenesis of meningitis caused by Streptococcus pneumoniae. Curr Opin Infect Dis 15: 253-257.
    • (2002) Curr Opin Infect Dis , vol.15 , pp. 253-257
    • Meli, D.N.1    Christen, S.2    Leib, S.L.3    Tauber, M.G.4
  • 25
    • 0033866076 scopus 로고    scopus 로고
    • Virulence factors and the pathogenesis of disease caused by Streptococcus pneumoniae
    • Mitchell, T.J. (2000) Virulence factors and the pathogenesis of disease caused by Streptococcus pneumoniae. Res Microbiol 151: 413-419.
    • (2000) Res Microbiol , vol.151 , pp. 413-419
    • Mitchell, T.J.1
  • 26
    • 1842372721 scopus 로고    scopus 로고
    • Invasion of brain microvascular endothelial cells by group B streptococci
    • Nizet, V., Kim, K., Stins, M., Jonas, M., Chi, E.Y., Nguyen, D., and Rubens, C.E. (1997) Invasion of brain microvascular endothelial cells by group B streptococci. Infect Immun 65: 5074-5081.
    • (1997) Infect Immun , vol.65 , pp. 5074-5081
    • Nizet, V.1    Kim, K.2    Stins, M.3    Jonas, M.4    Chi, E.Y.5    Nguyen, D.6    Rubens, C.E.7
  • 27
    • 0015058384 scopus 로고
    • Neuraminidase activity in bacterial meningitis
    • O'Toole, R.D., Goode, L., and Howe, C. (1971) Neuraminidase activity in bacterial meningitis. J Clin Invest 50: 979-985.
    • (1971) J Clin Invest , vol.50 , pp. 979-985
    • O'Toole, R.D.1    Goode, L.2    Howe, C.3
  • 28
    • 6944224035 scopus 로고    scopus 로고
    • Tissue specific contributions of pneumococcal virulence factors to pathogenesis
    • Orihuela, C.J., Gao, G., Francis, K.P., Yu, J., and Tuomanen, E.I. (2004) Tissue specific contributions of pneumococcal virulence factors to pathogenesis. J Infect Dis 190: 1661-1669.
    • (2004) J Infect Dis , vol.190 , pp. 1661-1669
    • Orihuela, C.J.1    Gao, G.2    Francis, K.P.3    Yu, J.4    Tuomanen, E.I.5
  • 29
    • 67651007158 scopus 로고    scopus 로고
    • Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models
    • Orihuela, C.J., Mahdavi, J., Thornton, J., Mann, B., Wooldridge, K.G., Abouseada, N., etal. (2009) Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models. J Clin Invest 119: 1638-1646.
    • (2009) J Clin Invest , vol.119 , pp. 1638-1646
    • Orihuela, C.J.1    Mahdavi, J.2    Thornton, J.3    Mann, B.4    Wooldridge, K.G.5    Abouseada, N.6
  • 30
    • 33646950675 scopus 로고    scopus 로고
    • Variation in the Presence of Neuraminidase Genes among Streptococcus pneumoniae Isolates with Identical Sequence Types
    • Pettigrew, M.M., Fennie, K.P., York, M.P., Daniels, J., and Ghaffar, F. (2006) Variation in the Presence of Neuraminidase Genes among Streptococcus pneumoniae Isolates with Identical Sequence Types. Infect Immun 74: 3360-3365.
    • (2006) Infect Immun , vol.74 , pp. 3360-3365
    • Pettigrew, M.M.1    Fennie, K.P.2    York, M.P.3    Daniels, J.4    Ghaffar, F.5
  • 31
    • 0030856428 scopus 로고    scopus 로고
    • Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia
    • Poll, T.V.D., Keogh, C.V., Guirao, X., Buurman, W.A., Kopf, M., and Lowry, S.F. (1997) Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia. J Infect Dis 176: 439-444.
    • (1997) J Infect Dis , vol.176 , pp. 439-444
    • Poll, T.V.D.1    Keogh, C.V.2    Guirao, X.3    Buurman, W.A.4    Kopf, M.5    Lowry, S.F.6
  • 32
    • 20244373759 scopus 로고    scopus 로고
    • PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation
    • Pracht, D., Elm, C., Gerber, J., Bergmann, S., Rohde, M., Seiler, M., etal. (2005) PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation. Infect Immun 73: 2680-2689.
    • (2005) Infect Immun , vol.73 , pp. 2680-2689
    • Pracht, D.1    Elm, C.2    Gerber, J.3    Bergmann, S.4    Rohde, M.5    Seiler, M.6
  • 33
    • 28444482410 scopus 로고    scopus 로고
    • beta-Arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae
    • Radin, J.N., Orihuela, C.J., Murti, G., Guglielmo, C., Murray, P.J., and Tuomanen, E.I. (2005) beta-Arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae. Infect Immun 73: 7827-7835.
    • (2005) Infect Immun , vol.73 , pp. 7827-7835
    • Radin, J.N.1    Orihuela, C.J.2    Murti, G.3    Guglielmo, C.4    Murray, P.J.5    Tuomanen, E.I.6
  • 34
    • 0032527622 scopus 로고    scopus 로고
    • Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway
    • Ring, A., Weiser, J.N., and Tuomanen, E.I. (1998) Pneumococcal trafficking across the blood-brain barrier. Molecular analysis of a novel bidirectional pathway. J Clin Invest 102: 347-360.
    • (1998) J Clin Invest , vol.102 , pp. 347-360
    • Ring, A.1    Weiser, J.N.2    Tuomanen, E.I.3
  • 35
    • 0027323231 scopus 로고
    • Determination of the sialic acid linkage specificity of sialidases using lectins in a solid phase assay
    • Rogerieux, F., Belaise, M., Terzidis-Trabelsi, H., Greffard, A., Pilatte, Y., and Lambre, C.R. (1993) Determination of the sialic acid linkage specificity of sialidases using lectins in a solid phase assay. Anal Biochem 211: 200-204.
    • (1993) Anal Biochem , vol.211 , pp. 200-204
    • Rogerieux, F.1    Belaise, M.2    Terzidis-Trabelsi, H.3    Greffard, A.4    Pilatte, Y.5    Lambre, C.R.6
  • 36
    • 12244298154 scopus 로고    scopus 로고
    • Statistical analysis of high-density oligonucleotide arrays: a multiplicative noise model
    • Sasik, R., Calvo, E., and Corbeil, J. (2002) Statistical analysis of high-density oligonucleotide arrays: a multiplicative noise model. Bioinformatics 18: 1633-1640.
    • (2002) Bioinformatics , vol.18 , pp. 1633-1640
    • Sasik, R.1    Calvo, E.2    Corbeil, J.3
  • 37
    • 0024588259 scopus 로고
    • Purification and properties of Streptococcus pneumoniae neuraminidase
    • Scanlon, K.L., Diven, W.F., and Glew, R.H. (1989) Purification and properties of Streptococcus pneumoniae neuraminidase. Enzyme 41: 143-150.
    • (1989) Enzyme , vol.41 , pp. 143-150
    • Scanlon, K.L.1    Diven, W.F.2    Glew, R.H.3
  • 38
    • 0036892227 scopus 로고    scopus 로고
    • Neuraminidase expressed by Streptococcus pneumoniae desialylates the lipopolysaccharide of Neisseria meningitidis and Haemophilus influenzae: a paradigm for interbacterial competition among pathogens of the human respiratory tract
    • Shakhnovich, E., King, S., and Wiser, J.N. (2002) Neuraminidase expressed by Streptococcus pneumoniae desialylates the lipopolysaccharide of Neisseria meningitidis and Haemophilus influenzae: a paradigm for interbacterial competition among pathogens of the human respiratory tract. Infect Immun 70: 7161-7164.
    • (2002) Infect Immun , vol.70 , pp. 7161-7164
    • Shakhnovich, E.1    King, S.2    Wiser, J.N.3
  • 39
    • 51849089723 scopus 로고    scopus 로고
    • Antrax toxins inhibit neutrophil signalling pathways in brain endothelium and contribute to the pathogenesis of meningitis
    • Sorge, N.M.V., Ebrahimi, C.M., McGillivray, S.M., Quach, D., Sabet, M., Guiney, D.G., and Doran, K.S. (2008) Antrax toxins inhibit neutrophil signalling pathways in brain endothelium and contribute to the pathogenesis of meningitis. PLoS ONE 3: e2964.
    • (2008) PLoS ONE , vol.3
    • Sorge, N.M.V.1    Ebrahimi, C.M.2    McGillivray, S.M.3    Quach, D.4    Sabet, M.5    Guiney, D.G.6    Doran, K.S.7
  • 40
    • 2942604709 scopus 로고    scopus 로고
    • Dystroglycan, a scaffold for the ERK-MAP kinase cascade
    • Spence, H.J., Dhillon, A.S., James, M., and Windler, S.J. (2004) Dystroglycan, a scaffold for the ERK-MAP kinase cascade. EMBO Rep 5: 484-489.
    • (2004) EMBO Rep , vol.5 , pp. 484-489
    • Spence, H.J.1    Dhillon, A.S.2    James, M.3    Windler, S.J.4
  • 41
    • 0028099213 scopus 로고
    • Binding characteristics of S fimbriated Escherichia coli to isolated brain microvascular endothelial cells
    • Stins, M.F., Prasadarao, N.V., Ibric, L., Wass, C.A., Luckett, P., and Kim, K.S. (1994) Binding characteristics of S fimbriated Escherichia coli to isolated brain microvascular endothelial cells. Am J Pathol 145: 1228-1336.
    • (1994) Am J Pathol , vol.145 , pp. 1228-1336
    • Stins, M.F.1    Prasadarao, N.V.2    Ibric, L.3    Wass, C.A.4    Luckett, P.5    Kim, K.S.6
  • 42
    • 0031110552 scopus 로고    scopus 로고
    • Bovine brain microvascular endothelial cells transfected with SV40-large T antigen: development of an immortalized cell line to study pathophysiology of CNS disease
    • Stins, M.F., Prasadarao, N.V., Zhou, J., Arditi, M., and Kim, K.S. (1997) Bovine brain microvascular endothelial cells transfected with SV40-large T antigen: development of an immortalized cell line to study pathophysiology of CNS disease. In Vitro Cell Dev Biol Anim 33: 243-247.
    • (1997) In Vitro Cell Dev Biol Anim , vol.33 , pp. 243-247
    • Stins, M.F.1    Prasadarao, N.V.2    Zhou, J.3    Arditi, M.4    Kim, K.S.5
  • 43
    • 0033557707 scopus 로고    scopus 로고
    • Binding of the G domains of laminin 1 and 2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix protein
    • Talts, J.F., Andac, Z., Gohring, W., Brancaccio, A., and Timpl, R. (1999) Binding of the G domains of laminin 1 and 2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix protein. EMBO J 18: 863-870.
    • (1999) EMBO J , vol.18 , pp. 863-870
    • Talts, J.F.1    Andac, Z.2    Gohring, W.3    Brancaccio, A.4    Timpl, R.5
  • 44
    • 0030444832 scopus 로고    scopus 로고
    • Sialidases: structures, biological significance and therapeutic potential
    • Taylor, G. (1996) Sialidases: structures, biological significance and therapeutic potential. Curr Opin Struct Biol 6: 830-837.
    • (1996) Curr Opin Struct Biol , vol.6 , pp. 830-837
    • Taylor, G.1
  • 45
    • 0033977389 scopus 로고    scopus 로고
    • Evaluation of the virulence of a Streptococcus pneumoniae neuraminidase deficient mutant in nasophraryngeal colonisation and development of otitis media in the chinchila model
    • Tong, H.H., Blue, L.E., James, M.A., and DeMaria, T.F. (2000) Evaluation of the virulence of a Streptococcus pneumoniae neuraminidase deficient mutant in nasophraryngeal colonisation and development of otitis media in the chinchila model. Infect Immun 68: 921-924.
    • (2000) Infect Immun , vol.68 , pp. 921-924
    • Tong, H.H.1    Blue, L.E.2    James, M.A.3    DeMaria, T.F.4
  • 46
    • 0035696749 scopus 로고    scopus 로고
    • Comparison of structural changes of cell surface carbohydrates in the eustachian tube epithelium of chinchilas infected with a Streptococcus pneumoniae neuraminidase deficient mutant or its isogenic parent strain
    • Tong, H.H., James, M.A., Grants, I., Liu, X., Shi, G., and DeMaria, T.F. (2001) Comparison of structural changes of cell surface carbohydrates in the eustachian tube epithelium of chinchilas infected with a Streptococcus pneumoniae neuraminidase deficient mutant or its isogenic parent strain. Microb Pathog 31: 309-317.
    • (2001) Microb Pathog , vol.31 , pp. 309-317
    • Tong, H.H.1    James, M.A.2    Grants, I.3    Liu, X.4    Shi, G.5    DeMaria, T.F.6
  • 47
    • 69549095908 scopus 로고    scopus 로고
    • The surface anchored NanA protein promotes pneumococcal brain endothelial cell invasion
    • Uchiyama, S., Carlin, A.F., Khosravi, A., Weiman, S., Banerjee, A., Quach, D., etal. (2009) The surface anchored NanA protein promotes pneumococcal brain endothelial cell invasion. J Exp Med 206: 1845-1852.
    • (2009) J Exp Med , vol.206 , pp. 1845-1852
    • Uchiyama, S.1    Carlin, A.F.2    Khosravi, A.3    Weiman, S.4    Banerjee, A.5    Quach, D.6
  • 48
    • 0036434984 scopus 로고    scopus 로고
    • Fibronectin mediates Opc-dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cells
    • Unkmeir, A., Latsch, K., Dietrich, G., Wintermeyer, E., Schinke, B., Schwender, S., etal. (2002) Fibronectin mediates Opc-dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cells. Mol Microbiol 46: 933-946.
    • (2002) Mol Microbiol , vol.46 , pp. 933-946
    • Unkmeir, A.1    Latsch, K.2    Dietrich, G.3    Wintermeyer, E.4    Schinke, B.5    Schwender, S.6
  • 49
    • 30844443240 scopus 로고    scopus 로고
    • Clinical features, complications, and outcome in adults with pneumococcal meningitis: a prospective case series
    • Weisfelt, M., Beek, D.V.D., Spanjaard, L., Reitsma, J.B., and Gans, J.D. (2006) Clinical features, complications, and outcome in adults with pneumococcal meningitis: a prospective case series. Lancet Neurol 5: 123-129.
    • (2006) Lancet Neurol , vol.5 , pp. 123-129
    • Weisfelt, M.1    Beek, D.V.D.2    Spanjaard, L.3    Reitsma, J.B.4    Gans, J.D.5
  • 50
    • 0030814940 scopus 로고    scopus 로고
    • A role for pneumolysin but not neuraminidase in the hearing loss and cochlear damage induced by experimental pneumococcal meningitis in guinea pigs
    • Winter, A.J., Comis, S.D., Osborne, M.P., Tarlow, M.J., Stephen, J., Andrew, P.W., etal. (1997) A role for pneumolysin but not neuraminidase in the hearing loss and cochlear damage induced by experimental pneumococcal meningitis in guinea pigs. Infect Immun 65: 4411-4418.
    • (1997) Infect Immun , vol.65 , pp. 4411-4418
    • Winter, A.J.1    Comis, S.D.2    Osborne, M.P.3    Tarlow, M.J.4    Stephen, J.5    Andrew, P.W.6
  • 52
    • 33745988952 scopus 로고    scopus 로고
    • Identification of amino acids essential for catalytic activity of pneumococcal neuraminidase A
    • Yesilkaya, H., Soma-Haddrick, S., Crennell, S.J., and Andrew, P.W. (2006) Identification of amino acids essential for catalytic activity of pneumococcal neuraminidase A. Res Microbiol 157: 569-575.
    • (2006) Res Microbiol , vol.157 , pp. 569-575
    • Yesilkaya, H.1    Soma-Haddrick, S.2    Crennell, S.J.3    Andrew, P.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.