GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii

PLoS Pathogens

Volumn 12, Issue 6, 2016, Pages

  David, Clément N ^a   Frias, Elma S ^a   Szu, Jenny I ^a   Vieira, Philip A ^b   Hubbard, Jacqueline A ^a   Lovelace, Jonathan ^b   Michael, Marena ^a   Worth, Danielle ^a   McGovern, Kathryn E ^a   Ethell, Iryna M ^a   Stanley, B Glenn ^b   Korzus, Edward ^b   Fiacco, Todd A ^b   Binder, Devin K ^a   Wilson, Emma H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; BETA TUBULIN; CEFTRIAXONE; GLUTAMIC ACID; HISTIDINE; LYSINE; PHENYLALANINE; PROLINE; SERINE; THREONINE; TRYPTOPHAN; TYROSINE; VESICULAR GLUTAMATE TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN METABOLISM; CONNECTOME; CONTROLLED STUDY; DENDRITIC SPINE; ELECTRIC ACTIVITY; ELECTROENCEPHALOGRAPHY; ELEVATED PLUS MAZE TEST; EXCITOTOXICITY; FEMALE; FLOW CYTOMETRY; FOREBRAIN; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY INFILTRATE; MICRODIALYSIS; MICROGLIA; MOUSE; NERVE FUNCTION; NEUROPROTECTION; NONHUMAN; PARASITE LOAD; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; TOXOPLASMA GONDII; TOXOPLASMOSIS; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; BRAIN; C57BL MOUSE; CENTRAL NERVOUS SYSTEM; CEREBRAL TOXOPLASMOSIS; DISEASE MODEL; METABOLISM; MICROBIOLOGY; NERVE CELL; PHYSIOLOGY; TOXOPLASMA; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; BRAIN; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; EXCITATORY AMINO ACID TRANSPORTER 2; FEMALE; GLUTAMIC ACID; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICRODIALYSIS; MICROSCOPY, ELECTRON, TRANSMISSION; NEURONS; REAL-TIME POLYMERASE CHAIN REACTION; TOXOPLASMA; TOXOPLASMOSIS, CEREBRAL;

EID: 84978881216     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005643     Document Type: Article

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