Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses

Nature Medicine

Volumn 19, Issue 4, 2013, Pages 458-464

  Cho, Hyelim ^a   Proll, Sean C ^b   Szretter, Kristy J ^a   Katze, Michael G ^b   Gale, Michael ^b   Diamond, Michael S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; MICRORNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; BRAIN REGION; CELL TYPE; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; EPIGENETICS; EX VIVO STUDY; FEMALE; FLAVIVIRUS INFECTION; GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC TRANSDUCTION; GRANULE CELL; HUMAN; HUMAN TISSUE; IFI27 GENE; IN VIVO STUDY; INFECTION SENSITIVITY; INNATE IMMUNITY; IRG1 GENE; MALE; MICROARRAY ANALYSIS; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA VIRUS; RNA VIRUS INFECTION; RSAD2 GENE; VIRUS ENCEPHALITIS; WEST NILE FLAVIVIRUS; WILD TYPE; ANIMAL; BRAIN; C57BL MOUSE; CYTOLOGY; DISEASE PREDISPOSITION; GENETIC EPIGENESIS; IMMUNOLOGY; NERVE CELL; PHYSIOLOGY; TISSUE MICROARRAY; VIROLOGY;

RNA VIRUSES;

ANIMALS; BRAIN; CEREBELLUM; CEREBRAL CORTEX; DISEASE SUSCEPTIBILITY; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, VIRAL; HUMANS; IMMUNITY, INNATE; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; NEURONS; RNA VIRUS INFECTIONS; TISSUE ARRAY ANALYSIS;

MLCS; MLOWN;

EID: 84877596501     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3108     Document Type: Article

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