Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment

Immunity

Volumn 44, Issue 4, 2016, Pages 901-912

  Blank, Thomas ^a   Detje, Claudia N ^b   Spieß, Alena ^a   Hagemeyer, Nora ^a   Brendecke, Stefanie M ^a   Wolfart, Jakob ^c   Staszewski, Ori ^a   Zöller, Tanja ^a   Papageorgiou, Ismini ^d   Schneider, Justus ^d   Paricio Montesinos, Ricardo ^a   Eisel, Ulrich L M ^e   Manahan Vaughan, Denise ^f   Jansen, Stephan ^f   Lienenklaus, Stefan ^b,g   Lu, Bao ^h   Imai, Yumiko ⁱ   Müller, Marcus ^j   Goelz, Susan E ^k   Baker, Darren P ^l   Schwaninger, Markus ^m   Kann, Oliver ^d   Heikenwalder, Mathias ^n,o   Kalinke, Ulrich ^b   Prinz, Marco ^a   more..

^a UNIVERSITY OF FREIBURG   (Germany)

^b INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^c UNIVERSITY OF ROSTOCK   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e UNIVERSITY OF GRONINGEN   (Netherlands)

^f RUHR UNIVERSITY BOCHUM   (Germany)

^g HANNOVER MEDICAL SCHOOL   (Germany)

^h BOSTON CHILDREN S HOSPITAL   (United States)

ⁱ AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^j UNIVERSITY HOSPITAL BONN   (Germany)

^k Portland ^*  (United States)

^l BIOGEN   (United States)

^m UNIVERSITY OF LÜBECK   (Germany)

ⁿ TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^o GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

more..

Author keywords

Behavior; Brain; CXCL10; CXCR3; Depression; Endothelia; Epithelia; IFN; IFNAR1; Influenza; IPS 1; MAVS; Neurons; Signal transduction; Type I interferon; Virus infection

Indexed keywords

BIOLOGICAL MARKER; CHEMOKINE RECEPTOR CXCR3; DOUBLE STRANDED RNA; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON RECEPTOR; MELANOMA DIFFERENTIATION ASSOCIATED PROTEIN 5; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; ALPHA BETA INTERFERON RECEPTOR; CXCL10 PROTEIN, MOUSE; CXCR3 PROTEIN, MOUSE; DDX58 PROTEIN, MOUSE; DEAD BOX PROTEIN; IFIH1 PROTEIN, MOUSE; IFNAR1 PROTEIN, MOUSE; INTERFERON; IPS-1 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR CHANGE; COGNITIVE DEFECT; ENDOTHELIUM CELL; EPITHELIUM CELL; GENE EXPRESSION PROFILING; ILLNESS BEHAVIOR; IMMUNE RESPONSE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA VIRUS INFECTION; SINGLE-STRANDED RNA VIRUS; ANIMAL; BRAIN; CELL COMMUNICATION; CELL CULTURE; CYTOLOGY; ENDOTHELIUM; EPITHELIUM; GENETICS; IMMUNOLOGY; MALE; METABOLISM; PHYSIOLOGY; PSYCHOLOGY; SIGNAL TRANSDUCTION; VIRUS INFECTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BRAIN; CELL COMMUNICATION; CELLS, CULTURED; CHEMOKINE CXCL10; COGNITION DISORDERS; DEAD-BOX RNA HELICASES; ENDOTHELIAL CELLS; ENDOTHELIUM; EPITHELIAL CELLS; EPITHELIUM; ILLNESS BEHAVIOR; INTERFERON TYPE I; MALE; MICE; RECEPTOR, INTERFERON ALPHA-BETA; RECEPTORS, CXCR3; RNA, DOUBLE-STRANDED; SIGNAL TRANSDUCTION; VIRUS DISEASES;

EID: 84964330538     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.04.005     Document Type: Article

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