메뉴 건너뛰기




Volumn 16, Issue 1, 2017, Pages

New developments in anti-malarial target candidate and product profiles

Author keywords

Elimination drug discovery; Eradication drug discovery; Malaria; Medicines; Plasmodium; Target candidate profile; Target product profile

Indexed keywords

ANTIMALARIAL AGENT;

EID: 85009442999     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/s12936-016-1675-x     Document Type: Review
Times cited : (373)

References (175)
  • 1
    • 84968896486 scopus 로고    scopus 로고
    • WHO Geneva, World Health Organization, 2015
    • WHO. World Malaria Report 2015. Geneva, World Health Organization, 2015. http://www.whoint/malaria/publications/world-malaria-report-2015/report/en/. 2015.
    • (2015) World Malaria Report 2015
  • 2
    • 79957703902 scopus 로고    scopus 로고
    • A research agenda for malaria eradication: Drugs
    • malERA Consultative Group on Drugs
    • malERA Consultative Group on Drugs. A research agenda for malaria eradication: drugs. PLoS Med. 2011;8:e1000402.
    • (2011) PLoS Med. , vol.8 , pp. e1000402
  • 3
    • 85009435506 scopus 로고    scopus 로고
    • WHO Geneva, World Health Organization
    • WHO. Global Technical Strategy for Malaria 2016-2030. Geneva, World Health Organization. http://www.whoint/malaria/areas/global-technical-strategy/en/. 2016.
    • (2016) Global Technical Strategy for Malaria 2016-2030
  • 7
    • 84964384823 scopus 로고    scopus 로고
    • Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: An open-label phase 2 trial
    • 1:CAS:528:DC%2BC2MXhs1Wjs7vP 26448141 4700386
    • Phyo AP, Jittamala P, Nosten FH, Pukrittayakamee S, Imwong M, White NJ, et al. Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial. Lancet Infect Dis. 2016;16:61-9.
    • (2016) Lancet Infect Dis. , vol.16 , pp. 61-69
    • Phyo, A.P.1    Jittamala, P.2    Nosten, F.H.3    Pukrittayakamee, S.4    Imwong, M.5    White, N.J.6
  • 9
    • 84908570528 scopus 로고    scopus 로고
    • A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel Imidazolopiperazine KAF156 to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers
    • 25136017 4249437
    • Leong FJ, Zhao R, Zeng S, Magnusson B, Diagana TT, Pertel P. A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel Imidazolopiperazine KAF156 to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers. Antimicrob Agents Chemother. 2014;58:6437-43.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 6437-6443
    • Leong, F.J.1    Zhao, R.2    Zeng, S.3    Magnusson, B.4    Diagana, T.T.5    Pertel, P.6
  • 11
    • 84937141039 scopus 로고    scopus 로고
    • A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
    • 26180101 4539048
    • Phillips MA, Lotharius J, Marsh K, White J, Dayan A, White KL, et al. A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria. Sci Transl Med. 2015;7:296ra111.
    • (2015) Sci Transl Med. , vol.7 , pp. 296ra111
    • Phillips, M.A.1    Lotharius, J.2    Marsh, K.3    White, J.4    Dayan, A.5    White, K.L.6
  • 12
    • 84892372929 scopus 로고    scopus 로고
    • A molecular marker of artemisinin-resistant Plasmodium falciparum malaria
    • 24352242
    • Ariey F, Witkowski B, Amaratunga C, Beghain J, Langlois AC, Khim N, et al. A molecular marker of artemisinin-resistant Plasmodium falciparum malaria. Nature. 2014;505:50-5.
    • (2014) Nature , vol.505 , pp. 50-55
    • Ariey, F.1    Witkowski, B.2    Amaratunga, C.3    Beghain, J.4    Langlois, A.C.5    Khim, N.6
  • 13
    • 84959170188 scopus 로고    scopus 로고
    • Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: A multisite prospective cohort study
    • 1:CAS:528:DC%2BC28XlsVWhsg%3D%3D 26774243
    • Amaratunga C, Lim P, Suon S, Sreng S, Mao S, Sopha C, et al. Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study. Lancet Infect Dis. 2016;16:357-65.
    • (2016) Lancet Infect Dis. , vol.16 , pp. 357-365
    • Amaratunga, C.1    Lim, P.2    Suon, S.3    Sreng, S.4    Mao, S.5    Sopha, C.6
  • 14
    • 84939832774 scopus 로고    scopus 로고
    • Evidence of Plasmodium falciparum malaria multidrug resistance to artemisinin and piperaquine in Western Cambodia: Dihydroartemisinin-piperaquine open-label multicenter clinical assessment
    • 1:CAS:528:DC%2BC2MXht1KntLzF 26014949 4505193
    • Leang R, Taylor WR, Bouth DM, Song L, Tarning J, Char MC, et al. Evidence of Plasmodium falciparum malaria multidrug resistance to artemisinin and piperaquine in Western Cambodia: dihydroartemisinin-piperaquine open-label multicenter clinical assessment. Antimicrob Agents Chemother. 2015;59:4719-26.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 4719-4726
    • Leang, R.1    Taylor, W.R.2    Bouth, D.M.3    Song, L.4    Tarning, J.5    Char, M.C.6
  • 15
    • 84994207103 scopus 로고    scopus 로고
    • Artemisinin resistance-associated K13 polymorphisms of Plasmodium falciparum in Southern Rwanda, 2010-2015
    • 27573632
    • Tacoli C, Gai PP, Bayingana C, Sifft K, Geus D, Ndoli J, et al. Artemisinin resistance-associated K13 polymorphisms of Plasmodium falciparum in Southern Rwanda, 2010-2015. Am J Trop Med Hyg. 2016;95:1090-3.
    • (2016) Am J Trop Med Hyg , vol.95 , pp. 1090-1093
    • Tacoli, C.1    Gai, P.P.2    Bayingana, C.3    Sifft, K.4    Geus, D.5    Ndoli, J.6
  • 16
    • 84961328499 scopus 로고    scopus 로고
    • Asymptomatic" malaria: A chronic and debilitating infection that should be treated
    • 26783752 4718522
    • Chen I, Clarke SE, Gosling R, Hamainza B, Killeen G, Magill A, et al. "Asymptomatic" malaria: a chronic and debilitating infection that should be treated. PLoS Med. 2016;13:e1001942.
    • (2016) PLoS Med. , vol.13 , pp. e1001942
    • Chen, I.1    Clarke, S.E.2    Gosling, R.3    Hamainza, B.4    Killeen, G.5    Magill, A.6
  • 18
    • 84954146531 scopus 로고    scopus 로고
    • Mind the gap: Residual malaria transmission, veterinary endectocides and livestock as targets for malaria vector control
    • 26755345 4709969
    • Chaccour C, Killeen GF. Mind the gap: residual malaria transmission, veterinary endectocides and livestock as targets for malaria vector control. Malar J. 2016;15:24.
    • (2016) Malar J. , vol.15 , pp. 24
    • Chaccour, C.1    Killeen, G.F.2
  • 19
    • 85009463590 scopus 로고    scopus 로고
    • http://www.endmalaria2040.org.
  • 20
    • 67650770309 scopus 로고    scopus 로고
    • Randomized, multicentre assessment of the efficacy and safety of ASAQ - A fixed-dose artesunate-amodiaquine combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria
    • 19505304 2698916
    • Ndiaye JL, Randrianarivelojosia M, Sagara I, Brasseur P, Ndiaye I, Faye B, et al. Randomized, multicentre assessment of the efficacy and safety of ASAQ - a fixed-dose artesunate-amodiaquine combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria. Malar J. 2009;8:125.
    • (2009) Malar J. , vol.8 , pp. 125
    • Ndiaye, J.L.1    Randrianarivelojosia, M.2    Sagara, I.3    Brasseur, P.4    Ndiaye, I.5    Faye, B.6
  • 21
    • 84957432274 scopus 로고    scopus 로고
    • Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: A substudy of the WANECAM randomised trial
    • 1:CAS:528:DC%2BC2MXhslantrrE 26601738 4726763
    • Sagara I, Beavogui AH, Zongo I, Soulama I, Borghini-Fuhrer I, Fofana B, et al. Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial. Lancet Infect Dis. 2016;16:189-98.
    • (2016) Lancet Infect Dis. , vol.16 , pp. 189-198
    • Sagara, I.1    Beavogui, A.H.2    Zongo, I.3    Soulama, I.4    Borghini-Fuhrer, I.5    Fofana, B.6
  • 22
    • 84877053096 scopus 로고    scopus 로고
    • Access to artemisinin-based anti-malarial treatment and its related factors in rural Tanzania
    • 1:CAS:528:DC%2BC3sXosVSmtL8%3D 23651521 3651283
    • Khatib RA, Selemani M, Mrisho GA, Masanja IM, Amuri M, Njozi MH, et al. Access to artemisinin-based anti-malarial treatment and its related factors in rural Tanzania. Malar J. 2013;12:155.
    • (2013) Malar J. , vol.12 , pp. 155
    • Khatib, R.A.1    Selemani, M.2    Mrisho, G.A.3    Masanja, I.M.4    Amuri, M.5    Njozi, M.H.6
  • 23
    • 84986617280 scopus 로고    scopus 로고
    • Quantifying the pharmacology of antimalarial drug combination therapy
    • 27604175 5036534
    • Hastings IM, Hodel EM, Kay K. Quantifying the pharmacology of antimalarial drug combination therapy. Sci Rep. 2016;6:32762.
    • (2016) Sci Rep. , vol.6 , pp. 32762
    • Hastings, I.M.1    Hodel, E.M.2    Kay, K.3
  • 24
    • 77955951674 scopus 로고    scopus 로고
    • Arterolane, a new synthetic trioxolane for treatment of uncomplicated Plasmodium falciparum malaria: A phase II, multicenter, randomized, dose-finding clinical trial
    • 1:CAS:528:DC%2BC3cXht1yhsbfM 20687837
    • Valecha N, Looareesuwan S, Martensson A, Abdulla SM, Krudsood S, Tangpukdee N, et al. Arterolane, a new synthetic trioxolane for treatment of uncomplicated Plasmodium falciparum malaria: a phase II, multicenter, randomized, dose-finding clinical trial. Clin Infect Dis. 2010;51:684-91.
    • (2010) Clin Infect Dis , vol.51 , pp. 684-691
    • Valecha, N.1    Looareesuwan, S.2    Martensson, A.3    Abdulla, S.M.4    Krudsood, S.5    Tangpukdee, N.6
  • 25
    • 84929645721 scopus 로고    scopus 로고
    • Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609 (Cipargamin) and piperaquine
    • 1:CAS:528:DC%2BC2MXpsFGisb8%3D 25845867 4432206
    • Stein DS, Jain JP, Kangas M, Lefevre G, Machineni S, Griffin P, et al. Open-label, single-dose, parallel-group study in healthy volunteers to determine the drug-drug interaction potential between KAE609 (Cipargamin) and piperaquine. Antimicrob Agents Chemother. 2015;59:3493-500.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 3493-3500
    • Stein, D.S.1    Jain, J.P.2    Kangas, M.3    Lefevre, G.4    Machineni, S.5    Griffin, P.6
  • 27
    • 84930373627 scopus 로고    scopus 로고
    • A phase I/Ib study to investigate the safety, tolerability and pharmacokinetic profile of DSM265 in healthy subjects and then its antimalarial activity in induced blood stage Plasmodium falciparum infection
    • McCarthy JS, Lotharius J, Dayan A, Phillips M, Marsh K, Walker D, et al. A phase I/Ib study to investigate the safety, tolerability and pharmacokinetic profile of DSM265 in healthy subjects and then its antimalarial activity in induced blood stage Plasmodium falciparum infection. ASTMH Ann. Meet. 2014;675:204-5.
    • (2014) ASTMH Ann. Meet. , vol.675 , pp. 204-205
    • McCarthy, J.S.1    Lotharius, J.2    Dayan, A.3    Phillips, M.4    Marsh, K.5    Walker, D.6
  • 28
    • 85009489990 scopus 로고    scopus 로고
    • A phase IIa proof-of-concept study to assess the efficacy, safety, tolerability and pharmacokinetics of single doses of DSM265 in adult patients with acute, uncomplicated Plasmodium falciparum or vivax malaria mono-infection over a 28-day-extended observation period in Iquitos, Peru
    • Philadelphia, USA, 2015
    • Rückle T, Duparc S, Kerr N, Rosario M, Qiu P, Phillips MA, et al. A phase IIa proof-of-concept study to assess the efficacy, safety, tolerability and pharmacokinetics of single doses of DSM265 in adult patients with acute, uncomplicated Plasmodium falciparum or vivax malaria mono-infection over a 28-day-extended observation period in Iquitos, Peru. In: ASTMH Annual Meeting. 2014;857. Philadelphia, USA, 2015.
    • (2014) ASTMH Annual Meeting , pp. 857
    • Rückle, T.1    Duparc, S.2    Kerr, N.3    Rosario, M.4    Qiu, P.5    Phillips, M.A.6
  • 29
    • 84960366822 scopus 로고    scopus 로고
    • Ferroquine and artesunate in African adults and children with Plasmodium falciparum malaria: A phase 2, multicentre, randomised, double-blind, dose-ranging, non-inferiority study
    • 1:CAS:528:DC%2BC2MXhsVOqtbjN 26342427
    • Held J, Supan C, Salazar CL, Tinto H, Bonkian LN, Nahum A, et al. Ferroquine and artesunate in African adults and children with Plasmodium falciparum malaria: a phase 2, multicentre, randomised, double-blind, dose-ranging, non-inferiority study. Lancet Infect Dis. 2015;15:1409-19.
    • (2015) Lancet Infect Dis. , vol.15 , pp. 1409-1419
    • Held, J.1    Supan, C.2    Salazar, C.L.3    Tinto, H.4    Bonkian, L.N.5    Nahum, A.6
  • 30
    • 84973582074 scopus 로고    scopus 로고
    • Linking murine and human Plasmodium falciparum challenge models in a translational path for antimalarial drug development
    • 1:CAS:528:DC%2BC28Xhs1OksLzO 27044554 4879391
    • McCarthy JS, Marquart L, Sekuloski S, Trenholme K, Elliott S, Griffin P, et al. Linking murine and human Plasmodium falciparum challenge models in a translational path for antimalarial drug development. Antimicrob Agents Chemother. 2016;60:3669-75.
    • (2016) Antimicrob Agents Chemother , vol.60 , pp. 3669-3675
    • McCarthy, J.S.1    Marquart, L.2    Sekuloski, S.3    Trenholme, K.4    Elliott, S.5    Griffin, P.6
  • 31
  • 32
    • 84928468640 scopus 로고    scopus 로고
    • Prospective observational study to evaluate the clinical safety of the fixed-dose artemisinin-based combination Eurartesim(R) (dihydroartemisinin/piperaquine), in public health facilities in Burkina Faso, Mozambique, Ghana, and Tanzania
    • 25885858 4405867
    • Baiden R, Oduro A, Halidou T, Gyapong M, Sie A, Macete E, et al. Prospective observational study to evaluate the clinical safety of the fixed-dose artemisinin-based combination Eurartesim(R) (dihydroartemisinin/piperaquine), in public health facilities in Burkina Faso, Mozambique, Ghana, and Tanzania. Malar J. 2015;14:160.
    • (2015) Malar J. , vol.14 , pp. 160
    • Baiden, R.1    Oduro, A.2    Halidou, T.3    Gyapong, M.4    Sie, A.5    Macete, E.6
  • 33
    • 84874002038 scopus 로고    scopus 로고
    • Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: An integrated analysis of individual patient data from six randomized clinical trials
    • 1:CAS:528:DC%2BC3sXltVSqsL0%3D 23433102 3598551
    • Duparc S, Borghini-Fuhrer I, Craft CJ, Arbe-Barnes S, Miller RM, Shin CS, et al. Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials. Malar J. 2013;12:70.
    • (2013) Malar J. , vol.12 , pp. 70
    • Duparc, S.1    Borghini-Fuhrer, I.2    Craft, C.J.3    Arbe-Barnes, S.4    Miller, R.M.5    Shin, C.S.6
  • 34
    • 84865859296 scopus 로고    scopus 로고
    • Plasmodium falciparum parasitaemia in the first half of pregnancy, uterine and umbilical artery blood flow, and foetal growth: A longitudinal Doppler ultrasound study
    • 22963509 3496585
    • Griffin JB, Lokomba V, Landis SH, Thorp JM Jr, Herring AH, Tshefu AK, et al. Plasmodium falciparum parasitaemia in the first half of pregnancy, uterine and umbilical artery blood flow, and foetal growth: a longitudinal Doppler ultrasound study. Malar J. 2012;11:319.
    • (2012) Malar J. , vol.11 , pp. 319
    • Griffin, J.B.1    Lokomba, V.2    Landis, S.H.3    Thorp, J.M.4    Herring, A.H.5    Tshefu, A.K.6
  • 35
    • 79952051804 scopus 로고    scopus 로고
    • Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children
    • 21352609 3055852
    • Nambozi M, Van Geertruyden JP, Hachizovu S, Chaponda M, Mukwamataba D, Mulenga M, et al. Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children. Malar J. 2011;10:50.
    • (2011) Malar J. , vol.10 , pp. 50
    • Nambozi, M.1    Van Geertruyden, J.P.2    Hachizovu, S.3    Chaponda, M.4    Mukwamataba, D.5    Mulenga, M.6
  • 36
    • 85009459437 scopus 로고    scopus 로고
    • EHO. Malaria in pregnancy Geneva, World Health Organization
    • EHO. Malaria in pregnancy. WHO Evidence Review Group meeting report. Geneva, World Health Organization. http://www.who.int/malaria/mpac/mpac-sept2015-erg-mip-report.pdf. 2015.
    • (2015) WHO Evidence Review Group Meeting Report
  • 37
    • 77956462719 scopus 로고    scopus 로고
    • Safety of artemether-lumefantrine in pregnant women with malaria: Results of a prospective cohort study in Zambia
    • 20809964 2944339
    • Manyando C, Mkandawire R, Puma L, Sinkala M, Mpabalwani E, Njunju E, et al. Safety of artemether-lumefantrine in pregnant women with malaria: results of a prospective cohort study in Zambia. Malar J. 2010;9:249.
    • (2010) Malar J. , vol.9 , pp. 249
    • Manyando, C.1    Mkandawire, R.2    Puma, L.3    Sinkala, M.4    Mpabalwani, E.5    Njunju, E.6
  • 38
    • 84978734727 scopus 로고    scopus 로고
    • Treatment regimens for pregnant women with falciparum malaria
    • 1:CAS:528:DC%2BC28XhtFaht7%2FN 27322015
    • Moore BR, Salman S, Davis TM. Treatment regimens for pregnant women with falciparum malaria. Expert Rev Anti Infect Ther. 2016;14:691-704.
    • (2016) Expert Rev Anti Infect Ther. , vol.14 , pp. 691-704
    • Moore, B.R.1    Salman, S.2    Davis, T.M.3
  • 39
    • 84901985409 scopus 로고    scopus 로고
    • Safety of artemether-lumefantrine exposure in first trimester of pregnancy: An observational cohort
    • 24884890 4040412
    • Mosha D, Mazuguni F, Mrema S, Sevene E, Abdulla S, Genton B. Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort. Malar J. 2014;13:197.
    • (2014) Malar J. , vol.13 , pp. 197
    • Mosha, D.1    Mazuguni, F.2    Mrema, S.3    Sevene, E.4    Abdulla, S.5    Genton, B.6
  • 40
    • 78049359991 scopus 로고    scopus 로고
    • Efficacy and safety of artemether-lumefantrine compared with quinine in pregnant women with uncomplicated Plasmodium falciparum malaria: An open-label, randomised, non-inferiority trial
    • 1:CAS:528:DC%2BC3cXhtlCgsbnE 20932805
    • Piola P, Nabasumba C, Turyakira E, Dhorda M, Lindegardh N, Nyehangane D, et al. Efficacy and safety of artemether-lumefantrine compared with quinine in pregnant women with uncomplicated Plasmodium falciparum malaria: an open-label, randomised, non-inferiority trial. Lancet Infect Dis. 2010;10:762-9.
    • (2010) Lancet Infect Dis. , vol.10 , pp. 762-769
    • Piola, P.1    Nabasumba, C.2    Turyakira, E.3    Dhorda, M.4    Lindegardh, N.5    Nyehangane, D.6
  • 41
    • 84879189895 scopus 로고    scopus 로고
    • The open access malaria box: A drug discovery catalyst for neglected diseases
    • 1:CAS:528:DC%2BC3sXhtVCms7zI 23798988 3684613
    • Spangenberg T, Burrows JN, Kowalczyk P, McDonald S, Wells TN, Willis P. The open access malaria box: a drug discovery catalyst for neglected diseases. PLoS ONE. 2013;8:e62906.
    • (2013) PLoS ONE , vol.8 , pp. e62906
    • Spangenberg, T.1    Burrows, J.N.2    Kowalczyk, P.3    McDonald, S.4    Wells, T.N.5    Willis, P.6
  • 42
    • 84975055690 scopus 로고    scopus 로고
    • A broad analysis of resistance development in the malaria parasite
    • 1:CAS:528:DC%2BC28XhtVaiu7nE 27301419 4912613
    • Corey VC, Lukens AK, Istvan ES, Lee MC, Franco V, Magistrado P, et al. A broad analysis of resistance development in the malaria parasite. Nat Commun. 2016;7:11901.
    • (2016) Nat Commun. , vol.7 , pp. 11901
    • Corey, V.C.1    Lukens, A.K.2    Istvan, E.S.3    Lee, M.C.4    Franco, V.5    Magistrado, P.6
  • 43
    • 84992199802 scopus 로고    scopus 로고
    • A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study
    • 27624471 5022189
    • McCarthy JS, Rückle T, Djeriou E, Cantalloube C, Ter-Minassian D, Baker M, et al. A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study. Malar J. 2016;15:469.
    • (2016) Malar J. , vol.15 , pp. 469
    • McCarthy, J.S.1    Rückle, T.2    Djeriou, E.3    Cantalloube, C.4    Ter-Minassian, D.5    Baker, M.6
  • 44
    • 84877311728 scopus 로고    scopus 로고
    • Malaria transmission after artemether-lumefantrine and dihydroartemisinin-piperaquine: A randomized trial
    • 1:CAS:528:DC%2BC3sXntVOrsL8%3D 23468056
    • Sawa P, Shekalaghe SA, Drakeley CJ, Sutherland CJ, Mweresa CK, Baidjoe AY, et al. Malaria transmission after artemether-lumefantrine and dihydroartemisinin-piperaquine: a randomized trial. J Infect Dis. 2013;207:1637-45.
    • (2013) J Infect Dis , vol.207 , pp. 1637-1645
    • Sawa, P.1    Shekalaghe, S.A.2    Drakeley, C.J.3    Sutherland, C.J.4    Mweresa, C.K.5    Baidjoe, A.Y.6
  • 45
    • 33646352709 scopus 로고    scopus 로고
    • Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure
    • 16464254 1395321
    • Daher W, Biot C, Fandeur T, Jouin H, Pelinski L, Viscogliosi E, et al. Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure. Malar J. 2006;5:11.
    • (2006) Malar J. , vol.5 , pp. 11
    • Daher, W.1    Biot, C.2    Fandeur, T.3    Jouin, H.4    Pelinski, L.5    Viscogliosi, E.6
  • 46
    • 84940901330 scopus 로고    scopus 로고
    • No robust evidence of lumefantrine resistance
    • 1:CAS:528:DC%2BC2MXhtlOltLvP 26276895 4538496
    • Hamed K, Kuhen K. No robust evidence of lumefantrine resistance. Antimicrob Agents Chemother. 2015;59:5865-6.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 5865-5866
    • Hamed, K.1    Kuhen, K.2
  • 47
    • 84958591009 scopus 로고    scopus 로고
    • Estimation of tafenoquine anti-relapse efficacy using Plasmodium vivax genotyping
    • 26500351
    • Beck HP, Wampfler R, Carter N, Koh G, Osorio L, Rueangweerayut R, et al. Estimation of tafenoquine anti-relapse efficacy using Plasmodium vivax genotyping. J Infect Dis. 2016;213:794-9.
    • (2016) J Infect Dis , vol.213 , pp. 794-799
    • Beck, H.P.1    Wampfler, R.2    Carter, N.3    Koh, G.4    Osorio, L.5    Rueangweerayut, R.6
  • 48
    • 84886415336 scopus 로고    scopus 로고
    • Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity
    • 1:CAS:528:DC%2BC3sXhslejsLbP 24101478 3808620
    • Rochford R, Ohrt C, Baresel PC, Campo B, Sampath A, Magill AJ, et al. Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity. Proc Natl Acad Sci USA. 2013;110:17486-91.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 17486-17491
    • Rochford, R.1    Ohrt, C.2    Baresel, P.C.3    Campo, B.4    Sampath, A.5    Magill, A.J.6
  • 49
    • 84962566015 scopus 로고    scopus 로고
    • Tuberculosis-advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers
    • 1:CAS:528:DC%2BC28Xksl2htbk%3D 27036358
    • Wallis RS, Maeurer M, Mwaba P, Chakaya J, Rustomjee R, Migliori GB, et al. Tuberculosis-advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers. Lancet Infect Dis. 2016;16:e34-46.
    • (2016) Lancet Infect Dis. , vol.16 , pp. e34-e46
    • Wallis, R.S.1    Maeurer, M.2    Mwaba, P.3    Chakaya, J.4    Rustomjee, R.5    Migliori, G.B.6
  • 50
    • 84977657386 scopus 로고    scopus 로고
    • Current scenario of HIV/AIDS, treatment options, and major challenges with compliance to antiretroviral therapy
    • 27054050 4818110
    • Bhatti AB, Usman M, Kandi V. Current scenario of HIV/AIDS, treatment options, and major challenges with compliance to antiretroviral therapy. Cureus. 2016;8:e515.
    • (2016) Cureus. , vol.8 , pp. e515
    • Bhatti, A.B.1    Usman, M.2    Kandi, V.3
  • 52
    • 84960126706 scopus 로고    scopus 로고
    • Malaria, anaemia and under-nutrition: Three frequently co-existing conditions among preschool children in rural Rwanda
    • 26542672 4635556
    • Kateera F, Ingabire CM, Hakizimana E, Kalinda P, Mens PF, Grobusch MP, et al. Malaria, anaemia and under-nutrition: three frequently co-existing conditions among preschool children in rural Rwanda. Malar J. 2015;14:440.
    • (2015) Malar J. , vol.14 , pp. 440
    • Kateera, F.1    Ingabire, C.M.2    Hakizimana, E.3    Kalinda, P.4    Mens, P.F.5    Grobusch, M.P.6
  • 53
    • 84991018129 scopus 로고    scopus 로고
    • Plasmodium parasitemia associated with increased survival in Ebola virus-infected patients
    • 27531847
    • Rosenke K, Adjemian J, Munster VJ, Marzi A, Falzarano D, Onyango CO, et al. Plasmodium parasitemia associated with increased survival in Ebola virus-infected patients. Clin Infect Dis. 2016;63:1026-33.
    • (2016) Clin Infect Dis , vol.63 , pp. 1026-1033
    • Rosenke, K.1    Adjemian, J.2    Munster, V.J.3    Marzi, A.4    Falzarano, D.5    Onyango, C.O.6
  • 54
    • 84856327673 scopus 로고    scopus 로고
    • The complexities of malaria disease manifestations with a focus on asymptomatic malaria
    • 22289302 3342920
    • Laishram DD, Sutton PL, Nanda N, Sharma VL, Sobti RC, Carlton JM, et al. The complexities of malaria disease manifestations with a focus on asymptomatic malaria. Malar J. 2012;11:29.
    • (2012) Malar J. , vol.11 , pp. 29
    • Laishram, D.D.1    Sutton, P.L.2    Nanda, N.3    Sharma, V.L.4    Sobti, R.C.5    Carlton, J.M.6
  • 55
    • 84976562952 scopus 로고    scopus 로고
    • Efficacy and safety of azithromycin-chloroquine versus sulfadoxine-pyrimethamine for intermittent preventive treatment of Plasmodium falciparum malaria infection in pregnant women in Africa: An open-label, randomized trial
    • 27326859 4915657
    • Kimani J, Phiri K, Kamiza S, Duparc S, Ayoub A, Rojo R, et al. Efficacy and safety of azithromycin-chloroquine versus sulfadoxine-pyrimethamine for intermittent preventive treatment of Plasmodium falciparum malaria infection in pregnant women in Africa: an open-label, randomized trial. PLoS ONE. 2016;11:e0157045.
    • (2016) PLoS ONE , vol.11 , pp. e0157045
    • Kimani, J.1    Phiri, K.2    Kamiza, S.3    Duparc, S.4    Ayoub, A.5    Rojo, R.6
  • 56
    • 85009491322 scopus 로고    scopus 로고
    • Fifteen years of interventions
    • Malaria Hemingway J. Fifteen years of interventions. Nature. 2015;526:198-9.
    • (2015) Nature , vol.526 , pp. 198-199
    • Malaria, H.J.1
  • 57
    • 84959529896 scopus 로고    scopus 로고
    • Public health impact and cost-effectiveness of the RTS, S/AS01 malaria vaccine: A systematic comparison of predictions from four mathematical models
    • 26549466
    • Penny MA, Verity R, Bever CA, Sauboin C, Galactionova K, Flasche S, et al. Public health impact and cost-effectiveness of the RTS, S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models. Lancet. 2015;387:367-75.
    • (2015) Lancet , vol.387 , pp. 367-375
    • Penny, M.A.1    Verity, R.2    Bever, C.A.3    Sauboin, C.4    Galactionova, K.5    Flasche, S.6
  • 58
    • 84937422078 scopus 로고    scopus 로고
    • Clinical Trials Partnership. Efficacy and safety of RTS, S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: Final results of a phase 3, individually randomised, controlled trial
    • Rts S. Clinical Trials Partnership. Efficacy and safety of RTS, S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. Lancet. 2015;386:31-45.
    • (2015) Lancet , vol.386 , pp. 31-45
    • Rts, S.1
  • 59
    • 84883600823 scopus 로고    scopus 로고
    • The whole parasite, pre-erythrocytic stage approach to malaria vaccine development: A review
    • 1:CAS:528:DC%2BC3sXhtlGrtrfL 23982233
    • Epstein JE, Richie TL. The whole parasite, pre-erythrocytic stage approach to malaria vaccine development: a review. Curr Opin Infect Dis. 2013;26:420-8.
    • (2013) Curr Opin Infect Dis. , vol.26 , pp. 420-428
    • Epstein, J.E.1    Richie, T.L.2
  • 60
    • 84938775301 scopus 로고    scopus 로고
    • Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naive volunteers: Effect of injection volume and dose on infectivity rates
    • 26245196 4527105
    • Gomez-Perez GP, Legarda A, Munoz J, Sim BK, Ballester MR, Dobano C, et al. Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naive volunteers: effect of injection volume and dose on infectivity rates. Malar J. 2015;14:306.
    • (2015) Malar J. , vol.14 , pp. 306
    • Gomez-Perez, G.P.1    Legarda, A.2    Munoz, J.3    Sim, B.K.4    Ballester, M.R.5    Dobano, C.6
  • 61
    • 84949660632 scopus 로고    scopus 로고
    • Optimizing intradermal administration of cryopreserved Plasmodium falciparum sporozoites in controlled human malaria infection
    • 1:CAS:528:DC%2BC28XnvFChsLc%3D 26416102 4674246
    • Lyke KE, Laurens MB, Strauss K, Adams M, Billingsley PF, James E, et al. Optimizing intradermal administration of cryopreserved Plasmodium falciparum sporozoites in controlled human malaria infection. Am J Trop Med Hyg. 2015;93:1274-84.
    • (2015) Am J Trop Med Hyg , vol.93 , pp. 1274-1284
    • Lyke, K.E.1    Laurens, M.B.2    Strauss, K.3    Adams, M.4    Billingsley, P.F.5    James, E.6
  • 62
    • 84914689866 scopus 로고    scopus 로고
    • Safety and comparability of controlled human Plasmodium falciparum infection by mosquito bite in malaria-naive subjects at a new facility for sporozoite challenge
    • 25405724 4236046
    • Talley AK, Healy SA, Finney OC, Murphy SC, Kublin J, Salas CJ, et al. Safety and comparability of controlled human Plasmodium falciparum infection by mosquito bite in malaria-naive subjects at a new facility for sporozoite challenge. PLoS ONE. 2014;9:e109654.
    • (2014) PLoS ONE , vol.9 , pp. e109654
    • Talley, A.K.1    Healy, S.A.2    Finney, O.C.3    Murphy, S.C.4    Kublin, J.5    Salas, C.J.6
  • 63
    • 84944712010 scopus 로고    scopus 로고
    • HIV pre-exposure prophylaxis (PrEP): A review of current knowledge of oral systemic HIV PrEP in humans
    • 26471511
    • Spinner CD, Boesecke C, Zink A, Jessen H, Stellbrink HJ, Rockstroh JK, et al. HIV pre-exposure prophylaxis (PrEP): a review of current knowledge of oral systemic HIV PrEP in humans. Infection. 2016;44:151-8.
    • (2016) Infection , vol.44 , pp. 151-158
    • Spinner, C.D.1    Boesecke, C.2    Zink, A.3    Jessen, H.4    Stellbrink, H.J.5    Rockstroh, J.K.6
  • 64
    • 84943146144 scopus 로고    scopus 로고
    • Long-acting antiviral agents for HIV treatment
    • 1:CAS:528:DC%2BC2MXpvFSjtLo%3D 26049949
    • Margolis DA, Boffito M. Long-acting antiviral agents for HIV treatment. Curr Opin HIV AIDS. 2015;10:246-52.
    • (2015) Curr Opin HIV AIDS. , vol.10 , pp. 246-252
    • Margolis, D.A.1    Boffito, M.2
  • 66
    • 84863318549 scopus 로고    scopus 로고
    • Estimating the potential public health impact of seasonal malaria chemoprevention in African children
    • 22673908 3621394
    • Cairns M, Roca-Feltrer A, Garske T, Wilson AL, Diallo D, Milligan PJ, et al. Estimating the potential public health impact of seasonal malaria chemoprevention in African children. Nat Commun. 2012;3:881.
    • (2012) Nat Commun. , vol.3 , pp. 881
    • Cairns, M.1    Roca-Feltrer, A.2    Garske, T.3    Wilson, A.L.4    Diallo, D.5    Milligan, P.J.6
  • 67
    • 84943327759 scopus 로고    scopus 로고
    • Sub-national targeting of seasonal malaria chemoprevention in the Sahelian countries of the Nouakchott Initiative
    • 26322634 4554730
    • Noor AM, Kibuchi E, Mitto B, Coulibaly D, Doumbo OK, Snow RW. Sub-national targeting of seasonal malaria chemoprevention in the Sahelian countries of the Nouakchott Initiative. PLoS ONE. 2015;10:e0136919.
    • (2015) PLoS ONE , vol.10 , pp. e0136919
    • Noor, A.M.1    Kibuchi, E.2    Mitto, B.3    Coulibaly, D.4    Doumbo, O.K.5    Snow, R.W.6
  • 68
    • 84978966770 scopus 로고    scopus 로고
    • Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: An individually randomised clinical trial
    • 26578353
    • Tagbor H, Antwi GD, Acheampong PR, Bart Plange C, Chandramohan D, Cairns M. Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial. Trop Med Int Health. 2016;21:224-35.
    • (2016) Trop Med Int Health. , vol.21 , pp. 224-235
    • Tagbor, H.1    Antwi, G.D.2    Acheampong, P.R.3    Bart Plange, C.4    Chandramohan, D.5    Cairns, M.6
  • 69
    • 84891316004 scopus 로고    scopus 로고
    • Feasibility, safety and effectiveness of combining home based malaria management and seasonal malaria chemoprevention in children less than 10 years in Senegal: A cluster-randomised trial
    • 1:CAS:528:DC%2BC2cXhvVWhtQ%3D%3D 24296325
    • Tine RC, Ndour CT, Faye B, Cairns M, Sylla K, Ndiaye M, et al. Feasibility, safety and effectiveness of combining home based malaria management and seasonal malaria chemoprevention in children less than 10 years in Senegal: a cluster-randomised trial. Trans R Soc Trop Med Hyg. 2014;108:13-21.
    • (2014) Trans R Soc Trop Med Hyg , vol.108 , pp. 13-21
    • Tine, R.C.1    Ndour, C.T.2    Faye, B.3    Cairns, M.4    Sylla, K.5    Ndiaye, M.6
  • 70
    • 84940183660 scopus 로고    scopus 로고
    • Randomized noninferiority trial of dihydroartemisinin-piperaquine compared with sulfadoxine-pyrimethamine plus amodiaquine for seasonal malaria chemoprevention in Burkina Faso
    • 1:CAS:528:DC%2BC2MXht1Gns77J 25918149 4505196
    • Zongo I, Milligan P, Compaore YD, Some AF, Greenwood B, Tarning J, et al. Randomized noninferiority trial of dihydroartemisinin-piperaquine compared with sulfadoxine-pyrimethamine plus amodiaquine for seasonal malaria chemoprevention in Burkina Faso. Antimicrob Agents Chemother. 2015;59:4387-96.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 4387-4396
    • Zongo, I.1    Milligan, P.2    Compaore, Y.D.3    Some, A.F.4    Greenwood, B.5    Tarning, J.6
  • 71
    • 84899587485 scopus 로고    scopus 로고
    • High levels of sulphadoxine-pyrimethamine resistance Pfdhfr-Pfdhps quintuple mutations: A cross sectional survey of six regions in Tanzania
    • 24751352 3998221
    • Matondo SI, Temba GS, Kavishe AA, Kauki JS, Kalinga A, van Zwetselaar M, et al. High levels of sulphadoxine-pyrimethamine resistance Pfdhfr-Pfdhps quintuple mutations: a cross sectional survey of six regions in Tanzania. Malar J. 2014;13:152.
    • (2014) Malar J. , vol.13 , pp. 152
    • Matondo, S.I.1    Temba, G.S.2    Kavishe, A.A.3    Kauki, J.S.4    Kalinga, A.5    Van Zwetselaar, M.6
  • 72
    • 31444454856 scopus 로고    scopus 로고
    • WHO Third edition. Geneva, World Health Organization
    • WHO. Guidelines for th treatment of malaria, Third edition. Geneva, World Health Organization. http://www.appswhoint/iris/bitstream/10665/162441/1/9789241549127-engpdf. 2015.
    • (2015) Guidelines for Th Treatment of Malaria
  • 74
    • 78449267241 scopus 로고    scopus 로고
    • Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): An open-label, randomised trial
    • 1:CAS:528:DC%2BC3cXhsVWmt7%2FO 21062666 3033534
    • Dondorp AM, Fanello CI, Hendriksen IC, Gomes E, Seni A, Chhaganlal KD, et al. Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet. 2010;376:1647-57.
    • (2010) Lancet , vol.376 , pp. 1647-1657
    • Dondorp, A.M.1    Fanello, C.I.2    Hendriksen, I.C.3    Gomes, E.4    Seni, A.5    Chhaganlal, K.D.6
  • 75
    • 23944443703 scopus 로고    scopus 로고
    • Artesunate versus quinine for treatment of severe falciparum malaria: A randomised trial
    • 16125588
    • Dondorp A, Nosten F, Stepniewska K, Day N, White N. Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet. 2005;366:717-25.
    • (2005) Lancet , vol.366 , pp. 717-725
    • Dondorp, A.1    Nosten, F.2    Stepniewska, K.3    Day, N.4    White, N.5
  • 77
    • 84961296997 scopus 로고    scopus 로고
    • Intramuscular srtesunate for severe malaria in African children: A multicenter randomized controlled trial
    • 26757276 4710539
    • Kremsner PG, Adegnika AA, Hounkpatin AB, Zinsou JF, Taylor TE, Chimalizeni Y, et al. Intramuscular srtesunate for severe malaria in African children: a multicenter randomized controlled trial. PLoS Med. 2016;13:e1001938.
    • (2016) PLoS Med. , vol.13 , pp. e1001938
    • Kremsner, P.G.1    Adegnika, A.A.2    Hounkpatin, A.B.3    Zinsou, J.F.4    Taylor, T.E.5    Chimalizeni, Y.6
  • 78
    • 36949016420 scopus 로고    scopus 로고
    • Cinchonism in a patient taking quinine for leg cramps
    • 18004031
    • Barrocas AM, Cymet T. Cinchonism in a patient taking quinine for leg cramps. Compr Ther. 2007;33:162-3.
    • (2007) Compr Ther , vol.33 , pp. 162-163
    • Barrocas, A.M.1    Cymet, T.2
  • 79
    • 0026683154 scopus 로고
    • Cinchonism: Two case reports and review of acute quinine toxicity and treatment
    • 1:STN:280:DyaK38zisFCjuw%3D%3D 1624742
    • Wolf LR, Otten EJ, Spadafora MP. Cinchonism: two case reports and review of acute quinine toxicity and treatment. J Emerg Med. 1992;10:295-301.
    • (1992) J Emerg Med , vol.10 , pp. 295-301
    • Wolf, L.R.1    Otten, E.J.2    Spadafora, M.P.3
  • 80
    • 84872931182 scopus 로고    scopus 로고
    • Published reports of delayed hemolytic anemia after treatment with artesunate for severe malaria - Worldwide, 2010-2012
    • Centers for Disease Control
    • Centers for Disease Control. Published reports of delayed hemolytic anemia after treatment with artesunate for severe malaria - worldwide, 2010-2012. MMWR Morb Mortal Wkly Rep. 2013;62:5-8.
    • (2013) MMWR Morb Mortal Wkly Rep , vol.62 , pp. 5-8
  • 81
    • 84904121729 scopus 로고    scopus 로고
    • Postartesunate delayed hemolysis is a predictable event related to the lifesaving effect of artemisinins
    • 1:CAS:528:DC%2BC2cXht1Wktb3L 24859359 4093678
    • Jaureguiberry S, Ndour PA, Roussel C, Ader F, Safeukui I, Nguyen M, et al. Postartesunate delayed hemolysis is a predictable event related to the lifesaving effect of artemisinins. Blood. 2014;124:167-75.
    • (2014) Blood , vol.124 , pp. 167-175
    • Jaureguiberry, S.1    Ndour, P.A.2    Roussel, C.3    Ader, F.4    Safeukui, I.5    Nguyen, M.6
  • 82
    • 84926421824 scopus 로고    scopus 로고
    • Delayed hemolysis after artesunate treatment of severe malaria - Review of the literature and perspective
    • 25812775
    • Rolling T, Agbenyega T, Krishna S, Kremsner PG, Cramer JP. Delayed haemolysis after artesunate treatment of severe malaria - review of the literature and perspective. Travel Med Infect Dis. 2015;13:143-9.
    • (2015) Travel Med Infect Dis. , vol.13 , pp. 143-149
    • Rolling, T.1    Agbenyega, T.2    Krishna, S.3    Kremsner, P.G.4    Cramer, J.P.5
  • 83
    • 84907263641 scopus 로고    scopus 로고
    • Pre-referral rectal artesunate for severe malaria
    • Okebe J, Eisenhut M. Pre-referral rectal artesunate for severe malaria. Cochrane Database Syst Rev. 2014;5:CD009964.
    • (2014) Cochrane Database Syst Rev. , vol.5 , pp. CD009964
    • Okebe, J.1    Eisenhut, M.2
  • 85
    • 84995740174 scopus 로고    scopus 로고
    • Development of drugs for severe malaria in children
    • 27620923 5039823
    • Cheah PY, Parker M, Dondorp AM. Development of drugs for severe malaria in children. Int Health. 2016;8:313-6.
    • (2016) Int Health. , vol.8 , pp. 313-316
    • Cheah, P.Y.1    Parker, M.2    Dondorp, A.M.3
  • 86
    • 84946491174 scopus 로고    scopus 로고
    • Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy
    • 26520795 4628286
    • Deng X, Duffy SP, Myrand-Lapierre ME, Matthews K, Santoso AT, Du YL, et al. Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy. Malar J. 2015;14:428.
    • (2015) Malar J. , vol.14 , pp. 428
    • Deng, X.1    Duffy, S.P.2    Myrand-Lapierre, M.E.3    Matthews, K.4    Santoso, A.T.5    Du, Y.L.6
  • 87
    • 84919363336 scopus 로고    scopus 로고
    • (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium
    • 1:CAS:528:DC%2BC2cXitVSitb3I 25453091 4273362
    • Jimenez-Diaz MB, Ebert D, Salinas Y, Pradhan A, Lehane AM, Myrand-Lapierre ME, et al. (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium. Proc Natl Acad Sci USA. 2014;111:E5455-62.
    • (2014) Proc Natl Acad Sci USA. , vol.111 , pp. E5455-E5462
    • Jimenez-Diaz, M.B.1    Ebert, D.2    Salinas, Y.3    Pradhan, A.4    Lehane, A.M.5    Myrand-Lapierre, M.E.6
  • 88
    • 84923327067 scopus 로고    scopus 로고
    • Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials
    • 1:CAS:528:DC%2BC2cXhslKktrnF 25322084
    • Flannery EL, McNamara CW, Kim SW, Kato TS, Li F, Teng CH, et al. Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials. ACS Chem Biol. 2015;10:413-20.
    • (2015) ACS Chem Biol , vol.10 , pp. 413-420
    • Flannery, E.L.1    McNamara, C.W.2    Kim, S.W.3    Kato, T.S.4    Li, F.5    Teng, C.H.6
  • 89
    • 84941220468 scopus 로고    scopus 로고
    • The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugs
    • 26401486 4559606
    • Spillman NJ, Kirk K. The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugs. Int J Parasitol Drugs Drug Resist. 2015;5:149-62.
    • (2015) Int J Parasitol Drugs Drug Resist. , vol.5 , pp. 149-162
    • Spillman, N.J.1    Kirk, K.2
  • 90
    • 84983474446 scopus 로고    scopus 로고
    • Sevuparin binds to multiple adhesive ligands and reduces sickle red blood cell-induced vaso-occlusion
    • 1:CAS:528:DC%2BC28XhvFKns7zE 27549988
    • Telen MJ, Batchvarova M, Shan S, Bovee-Geurts PH, Zennadi R, Leitgeb A, et al. Sevuparin binds to multiple adhesive ligands and reduces sickle red blood cell-induced vaso-occlusion. Br J Haematol. 2016;175:935-48.
    • (2016) Br J Haematol , vol.175 , pp. 935-948
    • Telen, M.J.1    Batchvarova, M.2    Shan, S.3    Bovee-Geurts, P.H.4    Zennadi, R.5    Leitgeb, A.6
  • 92
    • 84927911273 scopus 로고    scopus 로고
    • The pathogenesis of pediatric cerebral malaria: Eye exams, autopsies, and neuroimaging
    • 1:CAS:528:DC%2BC2MXotFansrw%3D 25708306 4405463
    • Taylor TE, Molyneux ME. The pathogenesis of pediatric cerebral malaria: eye exams, autopsies, and neuroimaging. Ann N Y Acad Sci. 2015;1342:44-52.
    • (2015) Ann N y Acad Sci , vol.1342 , pp. 44-52
    • Taylor, T.E.1    Molyneux, M.E.2
  • 93
    • 84994137736 scopus 로고    scopus 로고
    • The high blood pressure-malaria protection hypothesis
    • 1:CAS:528:DC%2BC28XhslCktrzK 27660286
    • Gallego-Delgado J, Walther T, Rodriguez A. The high blood pressure-malaria protection hypothesis. Circ Res. 2016;119:1071-5.
    • (2016) Circ Res , vol.119 , pp. 1071-1075
    • Gallego-Delgado, J.1    Walther, T.2    Rodriguez, A.3
  • 94
    • 84960115503 scopus 로고    scopus 로고
    • Risks of miscarriage and inadvertent exposure to artemisinin derivatives in the first trimester of pregnancy: A prospective cohort study in western Kenya
    • 26581434 4652370
    • Dellicour S, Desai M, Aol G, Oneko M, Ouma P, Bigogo G, et al. Risks of miscarriage and inadvertent exposure to artemisinin derivatives in the first trimester of pregnancy: a prospective cohort study in western Kenya. Malar J. 2015;14:461.
    • (2015) Malar J. , vol.14 , pp. 461
    • Dellicour, S.1    Desai, M.2    Aol, G.3    Oneko, M.4    Ouma, P.5    Bigogo, G.6
  • 95
    • 84860295622 scopus 로고    scopus 로고
    • Adverse effects of falciparum and vivax malaria and the safety of antimalarial treatment in early pregnancy: A population-based study
    • 1:CAS:528:DC%2BC38XmtlSrtLc%3D 22169409 3346948
    • McGready R, Lee SJ, Wiladphaingern J, Ashley EA, Rijken MJ, Boel M, et al. Adverse effects of falciparum and vivax malaria and the safety of antimalarial treatment in early pregnancy: a population-based study. Lancet Infect Dis. 2012;12:388-96.
    • (2012) Lancet Infect Dis. , vol.12 , pp. 388-396
    • McGready, R.1    Lee, S.J.2    Wiladphaingern, J.3    Ashley, E.A.4    Rijken, M.J.5    Boel, M.6
  • 96
    • 33846316714 scopus 로고    scopus 로고
    • Paediatric and geriatric drug delivery
    • 1:CAS:528:DC%2BD2sXhsFSjsr4%3D 17184161
    • Breitkreutz J, Boos J. Paediatric and geriatric drug delivery. Expert Opin Drug Deliv. 2007;4:37-45.
    • (2007) Expert Opin Drug Deliv , vol.4 , pp. 37-45
    • Breitkreutz, J.1    Boos, J.2
  • 97
    • 0028338817 scopus 로고
    • International conference on harmonisation of technical requirements for registration of pharmaceuticals for human use (ICH)
    • 1:STN:280:DyaK2czjtFaktw%3D%3D 8054244 1364893
    • Baber N. International conference on harmonisation of technical requirements for registration of pharmaceuticals for human use (ICH). Br J Clin Pharmacol. 1994;37:401-4.
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 401-404
    • Baber, N.1
  • 98
    • 84884701261 scopus 로고    scopus 로고
    • Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle
    • 1:CAS:528:DC%2BC3sXns1KnsLY%3D 23623858 3683851
    • Shimp RL Jr, Rowe C, Reiter K, Chen B, Nguyen V, Aebig J, et al. Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle. Vaccine. 2013;31:2954-62.
    • (2013) Vaccine. , vol.31 , pp. 2954-2962
    • Shimp, R.L.1    Rowe, C.2    Reiter, K.3    Chen, B.4    Nguyen, V.5    Aebig, J.6
  • 99
    • 84992083987 scopus 로고    scopus 로고
    • Assessment of Pfs25 expressed from multiple soluble expression platforms for use as transmission-blocking vaccine candidates
    • 27515826 4982271
    • Lee SM, Wu CK, Plieskatt J, McAdams DH, Miura K, Ockenhouse C, et al. Assessment of Pfs25 expressed from multiple soluble expression platforms for use as transmission-blocking vaccine candidates. Malar J. 2016;15:405.
    • (2016) Malar J. , vol.15 , pp. 405
    • Lee, S.M.1    Wu, C.K.2    Plieskatt, J.3    McAdams, D.H.4    Miura, K.5    Ockenhouse, C.6
  • 100
    • 84953896883 scopus 로고    scopus 로고
    • Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology
    • 1:CAS:528:DC%2BC28XnsFKnug%3D%3D 26743316 4705524
    • Li Y, Leneghan DB, Miura K, Nikolaeva D, Brian IJ, Dicks MD, et al. Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology. Sci Rep. 2016;6:18848.
    • (2016) Sci Rep. , vol.6 , pp. 18848
    • Li, Y.1    Leneghan, D.B.2    Miura, K.3    Nikolaeva, D.4    Brian, I.J.5    Dicks, M.D.6
  • 101
    • 84931292044 scopus 로고    scopus 로고
    • Comparative assessment of transmission-blocking vaccine candidates against Plasmodium falciparum
    • 1:STN:280:DC%2BC2MbisVCkug%3D%3D 26063320 4463016
    • Kapulu MC, Da DF, Miura K, Li Y, Blagborough AM, Churcher TS, et al. Comparative assessment of transmission-blocking vaccine candidates against Plasmodium falciparum. Sci Rep. 2015;5:11193.
    • (2015) Sci Rep. , vol.5 , pp. 11193
    • Kapulu, M.C.1    Da, D.F.2    Miura, K.3    Li, Y.4    Blagborough, A.M.5    Churcher, T.S.6
  • 102
    • 84928953352 scopus 로고    scopus 로고
    • Killing the hypnozoite-drug discovery approaches to prevent relapse in Plasmodium vivax
    • 1:CAS:528:DC%2BC2MXmvVyks7k%3D 25891812 4455353
    • Campo B, Vandal O, Wesche DL, Burrows JN. Killing the hypnozoite-drug discovery approaches to prevent relapse in Plasmodium vivax. Pathog Glob Health. 2015;109:107-22.
    • (2015) Pathog Glob Health. , vol.109 , pp. 107-122
    • Campo, B.1    Vandal, O.2    Wesche, D.L.3    Burrows, J.N.4
  • 103
    • 84864243685 scopus 로고    scopus 로고
    • Shock and kill
    • 1:CAS:528:DC%2BC38XhtFWjtb%2FK 22836995
    • Deeks SGHIV. Shock and kill. Nature. 2012;487:439-40.
    • (2012) Nature , vol.487 , pp. 439-440
    • Deeks, S.G.H.I.V.1
  • 104
    • 67649259174 scopus 로고    scopus 로고
    • Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence
    • 19486542 2697151
    • Savarino A, Mai A, Norelli S, El Daker S, Valente S, Rotili D, et al. "Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence. Retrovirology. 2009;6:52.
    • (2009) Retrovirology. , vol.6 , pp. 52
    • Savarino, A.1    Mai, A.2    Norelli, S.3    El Daker, S.4    Valente, S.5    Rotili, D.6
  • 105
    • 84892519249 scopus 로고    scopus 로고
    • Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: A randomised, controlled, double-blind, dose-ranging trial
    • 1:CAS:528:DC%2BC3sXhslOktb%2FM 24239324
    • Eziefula AC, Bousema T, Yeung S, Kamya M, Owaraganise A, Gabagaya G, et al. Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial. Lancet Infect Dis. 2014;14:130-9.
    • (2014) Lancet Infect Dis. , vol.14 , pp. 130-139
    • Eziefula, A.C.1    Bousema, T.2    Yeung, S.3    Kamya, M.4    Owaraganise, A.5    Gabagaya, G.6
  • 106
    • 85007413383 scopus 로고    scopus 로고
    • Single low dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission after artemether-lumefantrine in children with asymptomatic infection: A randomised, double-blind, placebo-controlled trial
    • 26952094 4782330
    • Goncalves BP, Tiono AB, Ouedraogo A, Guelbeogo WM, Bradley J, Nebie I, et al. Single low dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission after artemether-lumefantrine in children with asymptomatic infection: a randomised, double-blind, placebo-controlled trial. BMC Med. 2016;14:40.
    • (2016) BMC Med , vol.14 , pp. 40
    • Goncalves, B.P.1    Tiono, A.B.2    Ouedraogo, A.3    Guelbeogo, W.M.4    Bradley, J.5    Nebie, I.6
  • 107
    • 79955069542 scopus 로고    scopus 로고
    • Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination
    • 21482730 3122489
    • Bousema T, Drakeley C. Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination. Clin Microbiol Rev. 2011;24:377-410.
    • (2011) Clin Microbiol Rev , vol.24 , pp. 377-410
    • Bousema, T.1    Drakeley, C.2
  • 108
    • 84963746006 scopus 로고    scopus 로고
    • A luciferase-based, high-throughput assay for screening and profiling transmission-blocking compounds against Plasmodium falciparum gametocytes
    • 1:CAS:528:DC%2BC28Xht1Wqt7bF 26787698 4808229
    • Lucantoni L, Fidock DA, Avery VM. A luciferase-based, high-throughput assay for screening and profiling transmission-blocking compounds against Plasmodium falciparum gametocytes. Antimicrob Agents Chemother. 2016;60:2097-107.
    • (2016) Antimicrob Agents Chemother , vol.60 , pp. 2097-2107
    • Lucantoni, L.1    Fidock, D.A.2    Avery, V.M.3
  • 109
    • 84936817717 scopus 로고    scopus 로고
    • Targeting human transmission biology for malaria elimination
    • 26086192 4472755
    • Nilsson SK, Childs LM, Buckee C, Marti M. Targeting human transmission biology for malaria elimination. PLoS Pathog. 2015;11:e1004871.
    • (2015) PLoS Pathog , vol.11 , pp. e1004871
    • Nilsson, S.K.1    Childs, L.M.2    Buckee, C.3    Marti, M.4
  • 110
    • 79960261132 scopus 로고    scopus 로고
    • Ivermectin mass drug administration to humans disrupts malaria parasite transmission in Senegalese villages
    • 1:CAS:528:DC%2BC3MXpvVaguro%3D 21734116 3122335
    • Kobylinski KC, Sylla M, Chapman PL, Sarr MD, Foy BD. Ivermectin mass drug administration to humans disrupts malaria parasite transmission in Senegalese villages. Am J Trop Med Hyg. 2011;85:3-5.
    • (2011) Am J Trop Med Hyg , vol.85 , pp. 3-5
    • Kobylinski, K.C.1    Sylla, M.2    Chapman, P.L.3    Sarr, M.D.4    Foy, B.D.5
  • 111
    • 84908037226 scopus 로고    scopus 로고
    • Defining the biology component of the drug discovery strategy for malaria eradication
    • 1:CAS:528:DC%2BC2cXhtlSru7%2FL 25131411
    • Leroy D, Campo B, Ding X, Burrows JN, Cherbuin S. Defining the biology component of the drug discovery strategy for malaria eradication. Trends Parasitol. 2014;30:478-90.
    • (2014) Trends Parasitol , vol.30 , pp. 478-490
    • Leroy, D.1    Campo, B.2    Ding, X.3    Burrows, J.N.4    Cherbuin, S.5
  • 113
    • 85009440308 scopus 로고    scopus 로고
    • A Phase IIa clinical trial to characterize the pharmacokinetic-pharmacodynamic relationship of piperaquine using the induced blood stage infection model
    • McCarthy JS, Sekuloski S, Griffin P, Elliott S, Marquart L, Jörg M, et al. A Phase IIa clinical trial to characterize the pharmacokinetic-pharmacodynamic relationship of piperaquine using the induced blood stage infection model. ASTMH Ann Meet. 2014; 152. http://tinyurl.com/z9ng9df
    • (2014) ASTMH Ann Meet. , pp. 152
    • McCarthy, J.S.1    Sekuloski, S.2    Griffin, P.3    Elliott, S.4    Marquart, L.5    Jörg, M.6
  • 114
    • 84888627708 scopus 로고    scopus 로고
    • Experimentally induced blood-stage Plasmodium vivax infection in healthy volunteers
    • 1:CAS:528:DC%2BC3sXhs1yrs73I 23908484 3888148
    • McCarthy JS, Griffin PM, Sekuloski S, Bright AT, Rockett R, Looke D, et al. Experimentally induced blood-stage Plasmodium vivax infection in healthy volunteers. J Infect Dis. 2013;208:1688-94.
    • (2013) J Infect Dis , vol.208 , pp. 1688-1694
    • McCarthy, J.S.1    Griffin, P.M.2    Sekuloski, S.3    Bright, A.T.4    Rockett, R.5    Looke, D.6
  • 115
    • 84887416507 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic considerations in antimalarial dose optimization
    • 1:CAS:528:DC%2BC3sXhvVCjtbbO 24002099 3837842
    • White NJ. Pharmacokinetic and pharmacodynamic considerations in antimalarial dose optimization. Antimicrob Agents Chemother. 2013;57:5792-807.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 5792-5807
    • White, N.J.1
  • 116
    • 84857591058 scopus 로고    scopus 로고
    • P. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-action
    • 1:CAS:528:DC%2BC38XjsFynsLY%3D 22383983 3285618
    • Sanz LM, Crespo B, De-Cozar C, Ding XC, Llergo JL, Burrows JN, et al. P. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-action. PLoS ONE. 2012;7:e30949.
    • (2012) PLoS ONE , vol.7 , pp. e30949
    • Sanz, L.M.1    Crespo, B.2    De-Cozar, C.3    Ding, X.C.4    Llergo, J.L.5    Burrows, J.N.6
  • 117
    • 84960107074 scopus 로고    scopus 로고
    • Identifying rapidly parasiticidal anti-malarial drugs using a simple and reliable in vitro parasite viability fast assay
    • 26542470 4635989
    • Linares M, Viera S, Crespo B, Franco V, Gomez-Lorenzo MG, Jimenez-Diaz MB, et al. Identifying rapidly parasiticidal anti-malarial drugs using a simple and reliable in vitro parasite viability fast assay. Malar J. 2015;14:441.
    • (2015) Malar J. , vol.14 , pp. 441
    • Linares, M.1    Viera, S.2    Crespo, B.3    Franco, V.4    Gomez-Lorenzo, M.G.5    Jimenez-Diaz, M.B.6
  • 118
    • 70349313478 scopus 로고    scopus 로고
    • Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-SCID IL2Rγ-null mice engrafted with human erythrocytes
    • 19596869 2764183
    • Jiménez-Díaz MB, Mulet T, Viera S, Gómez V, Garuti H, Ibáñez J, et al. Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-SCID IL2Rγ-null mice engrafted with human erythrocytes. Antimicrob Agents Chemother. 2009;53:4533-6.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 4533-4536
    • Jiménez-Díaz, M.B.1    Mulet, T.2    Viera, S.3    Gómez, V.4    Garuti, H.5    Ibáñez, J.6
  • 119
    • 84927924779 scopus 로고    scopus 로고
    • Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines
    • 25890156 4392471
    • Stanisic DI, Liu XQ, De SL, Batzloff MR, Forbes T, Davis CB, et al. Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines. Malar J. 2015;14:143.
    • (2015) Malar J. , vol.14 , pp. 143
    • Stanisic, D.I.1    Liu, X.Q.2    De, S.L.3    Batzloff, M.R.4    Forbes, T.5    Davis, C.B.6
  • 120
    • 40149108218 scopus 로고    scopus 로고
    • Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria
    • 18205945 2259365
    • Ndiaye JL, Faye B, Diouf AM, Kuete T, Cisse M, Seck PA, et al. Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria. Malar J. 2008;7:16.
    • (2008) Malar J. , vol.7 , pp. 16
    • Ndiaye, J.L.1    Faye, B.2    Diouf, A.M.3    Kuete, T.4    Cisse, M.5    Seck, P.A.6
  • 122
    • 84979248000 scopus 로고    scopus 로고
    • Piperaquine monotherapy of drug-susceptible Plasmodium falciparum infection results in rapid clearance of parasitemia but is followed by the appearance of gametocytemia
    • 27056954 4907420
    • Pasay CJ, Rockett R, Sekuloski S, Griffin P, Marquart L, Peatey C, et al. Piperaquine monotherapy of drug-susceptible Plasmodium falciparum infection results in rapid clearance of parasitemia but is followed by the appearance of gametocytemia. J Infect Dis. 2016;214:105-13.
    • (2016) J Infect Dis , vol.214 , pp. 105-113
    • Pasay, C.J.1    Rockett, R.2    Sekuloski, S.3    Griffin, P.4    Marquart, L.5    Peatey, C.6
  • 123
    • 0020592196 scopus 로고
    • A double-blind comparative clinical trial of mefloquine and chloroquine in symptomatic falciparum malaria
    • 1:STN:280:DyaL2c%2Fis12ksw%3D%3D 6354507
    • Kofi Ekue JM, Ulrich AM, Rwabwogo-Atenyi J, Sheth UK. A double-blind comparative clinical trial of mefloquine and chloroquine in symptomatic falciparum malaria. Bull World Health Organ. 1983;61:713-8.
    • (1983) Bull World Health Organ , vol.61 , pp. 713-718
    • Kofi Ekue, J.M.1    Ulrich, A.M.2    Rwabwogo-Atenyi, J.3    Sheth, U.K.4
  • 124
    • 84976907427 scopus 로고    scopus 로고
    • Efficacy and safety of pyronaridine-artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in western Cambodia
    • 1:CAS:528:DC%2BC28XhvFSjtLbI 26926629 4914696
    • Leang R, Canavati SE, Khim N, Vestergaard LS, Borghini Fuhrer I, Kim S, et al. Efficacy and safety of pyronaridine-artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in western Cambodia. Antimicrob Agents Chemother. 2016;60:3884-90.
    • (2016) Antimicrob Agents Chemother , vol.60 , pp. 3884-3890
    • Leang, R.1    Canavati, S.E.2    Khim, N.3    Vestergaard, L.S.4    Borghini Fuhrer, I.5    Kim, S.6
  • 125
    • 84896134875 scopus 로고    scopus 로고
    • Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures
    • 1:CAS:528:DC%2BC2cXitFaqt7w%3D 24509527
    • Dembele L, Franetich JF, Lorthiois A, Gego A, Zeeman AM, Kocken CH, et al. Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures. Nat Med. 2014;20:307-12.
    • (2014) Nat Med , vol.20 , pp. 307-312
    • Dembele, L.1    Franetich, J.F.2    Lorthiois, A.3    Gego, A.4    Zeeman, A.M.5    Kocken, C.H.6
  • 127
    • 38049011979 scopus 로고    scopus 로고
    • Microscale culture of human liver cells for drug development
    • 1:CAS:528:DC%2BD1cXisFGlsg%3D%3D 18026090
    • Khetani SR, Bhatia SN. Microscale culture of human liver cells for drug development. Nat Biotechnol. 2008;26:120-6.
    • (2008) Nat Biotechnol , vol.26 , pp. 120-126
    • Khetani, S.R.1    Bhatia, S.N.2
  • 128
    • 33745027681 scopus 로고    scopus 로고
    • Establishment of a human hepatocyte line that supports in vitro development of the exo-erythrocytic stages of the malaria parasites Plasmodium falciparum and P. vivax
    • 1:CAS:528:DC%2BD28XlsVKiu7s%3D 16687667
    • Sattabongkot J, Yimamnuaychoke N, Leelaudomlipi S, Rasameesoraj M, Jenwithisuk R, Coleman RE, et al. Establishment of a human hepatocyte line that supports in vitro development of the exo-erythrocytic stages of the malaria parasites Plasmodium falciparum and P. vivax. Am J Trop Med Hyg. 2006;74:708-15.
    • (2006) Am J Trop Med Hyg , vol.74 , pp. 708-715
    • Sattabongkot, J.1    Yimamnuaychoke, N.2    Leelaudomlipi, S.3    Rasameesoraj, M.4    Jenwithisuk, R.5    Coleman, R.E.6
  • 129
    • 84969930673 scopus 로고    scopus 로고
    • Phenotypic screens in antimalarial drug discovery
    • 1:CAS:528:DC%2BC28XntVCgsbs%3D 27247245
    • Hovlid ML, Winzeler EA. Phenotypic screens in antimalarial drug discovery. Trends Parasitol. 2016;32:697-707.
    • (2016) Trends Parasitol , vol.32 , pp. 697-707
    • Hovlid, M.L.1    Winzeler, E.A.2
  • 131
    • 84951814027 scopus 로고    scopus 로고
    • A simple and efficient method for cryopreservation and recovery of viable Plasmodium vivax and P. falciparum sporozoites
    • 1:CAS:528:DC%2BC2MXitVSksL%2FI 26680158
    • Singh N, Barnes SJ, Jenwithisuk R, Sattabongkot J, Adams JH. A simple and efficient method for cryopreservation and recovery of viable Plasmodium vivax and P. falciparum sporozoites. Parasitol Int. 2016;65:552-7.
    • (2016) Parasitol Int. , vol.65 , pp. 552-557
    • Singh, N.1    Barnes, S.J.2    Jenwithisuk, R.3    Sattabongkot, J.4    Adams, J.H.5
  • 132
    • 84880397868 scopus 로고    scopus 로고
    • A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax
    • 1:CAS:528:DC%2BC3sXhtFaksb%2FN 23870318 3780791
    • March S, Ng S, Velmurugan S, Galstian A, Shan J, Logan DJ, et al. A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax. Cell Host Microbe. 2013;14:104-15.
    • (2013) Cell Host Microbe , vol.14 , pp. 104-115
    • March, S.1    Ng, S.2    Velmurugan, S.3    Galstian, A.4    Shan, J.5    Logan, D.J.6
  • 133
    • 76749083725 scopus 로고    scopus 로고
    • Targeting the hypnozoite reservoir of Plasmodium vivax: The hidden obstacle to malaria elimination
    • 20133198
    • Wells TN, Burrows JN, Baird JK. Targeting the hypnozoite reservoir of Plasmodium vivax: the hidden obstacle to malaria elimination. Trends Parasitol. 2010;26:145-51.
    • (2010) Trends Parasitol , vol.26 , pp. 145-151
    • Wells, T.N.1    Burrows, J.N.2    Baird, J.K.3
  • 135
    • 84952870456 scopus 로고    scopus 로고
    • Randomized trial of primaquine hypnozoitocidal efficacy when administered with artemisinin-combined blood schizontocides for radical cure of Plasmodium vivax in Indonesia
    • 26654101 4676167
    • Nelwan EJ, Ekawati LL, Tjahjono B, Setiabudy R, Sutanto I, Chand K, et al. Randomized trial of primaquine hypnozoitocidal efficacy when administered with artemisinin-combined blood schizontocides for radical cure of Plasmodium vivax in Indonesia. BMC Med. 2015;13:294.
    • (2015) BMC Med , vol.13 , pp. 294
    • Nelwan, E.J.1    Ekawati, L.L.2    Tjahjono, B.3    Setiabudy, R.4    Sutanto, I.5    Chand, K.6
  • 136
    • 84905501916 scopus 로고    scopus 로고
    • Tafenoquine at therapeutic concentrations does not prolong fridericia-corrected QT interval in healthy subjects
    • 1:CAS:528:DC%2BC2cXhtlWgurrO 24700490 4283056
    • Green JA, Patel AK, Patel BR, Hussaini A, Harrell EJ, McDonald MJ, et al. Tafenoquine at therapeutic concentrations does not prolong fridericia-corrected QT interval in healthy subjects. J Clin Pharmacol. 2014;54:995-1005.
    • (2014) J Clin Pharmacol , vol.54 , pp. 995-1005
    • Green, J.A.1    Patel, A.K.2    Patel, B.R.3    Hussaini, A.4    Harrell, E.J.5    McDonald, M.J.6
  • 137
    • 84896489887 scopus 로고    scopus 로고
    • Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): A multicentre, double-blind, randomised, phase 2b dose-selection study
    • 1:CAS:528:DC%2BC3sXhvFyru7nP 24360369
    • Llanos-Cuentas A, Lacerda MV, Rueangweerayut R, Krudsood S, Gupta SK, Kochar SK, et al. Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b dose-selection study. Lancet. 2014;383:1049-58.
    • (2014) Lancet , vol.383 , pp. 1049-1058
    • Llanos-Cuentas, A.1    Lacerda, M.V.2    Rueangweerayut, R.3    Krudsood, S.4    Gupta, S.K.5    Kochar, S.K.6
  • 138
    • 84876146784 scopus 로고    scopus 로고
    • Quantitative bioluminescent imaging of pre-erythrocytic malaria parasite infection using luciferase-expressing Plasmodium yoelii
    • 1:CAS:528:DC%2BC3sXmsFGntbg%3D 23593316 3623966
    • Miller JL, Murray S, Vaughan AM, Harupa A, Sack B, Baldwin M, et al. Quantitative bioluminescent imaging of pre-erythrocytic malaria parasite infection using luciferase-expressing Plasmodium yoelii. PLoS ONE. 2013;8:e60820.
    • (2013) PLoS ONE , vol.8 , pp. e60820
    • Miller, J.L.1    Murray, S.2    Vaughan, A.M.3    Harupa, A.4    Sack, B.5    Baldwin, M.6
  • 139
    • 84860846235 scopus 로고    scopus 로고
    • Development of humanized mouse models to study human malaria parasite infection
    • 22568719
    • Vaughan AM, Kappe SH, Ploss A, Mikolajczak SA. Development of humanized mouse models to study human malaria parasite infection. Future Microbiol. 2012;7:657-65.
    • (2012) Future Microbiol. , vol.7 , pp. 657-665
    • Vaughan, A.M.1    Kappe, S.H.2    Ploss, A.3    Mikolajczak, S.A.4
  • 141
    • 0014906570 scopus 로고
    • Field trial of cycloguanil pamoate in the treatment and suppression of malaria in Nigerian school children: A preliminary report
    • 1:STN:280:DyaE3M%2FoslSgtg%3D%3D 5495634
    • Fasan PO. Field trial of cycloguanil pamoate in the treatment and suppression of malaria in Nigerian school children: a preliminary report. Trans R Soc Trop Med Hyg. 1970;64:839-49.
    • (1970) Trans R Soc Trop Med Hyg , vol.64 , pp. 839-849
    • Fasan, P.O.1
  • 142
    • 0014021884 scopus 로고
    • Cycloguanil pamoate in the treatment and suppression of malaria in the Gambia, West Africa
    • 1:STN:280:DyaF287gvFelsw%3D%3D 5909480 1844242
    • McGregor IA, Williams K, Walker GH, Rahman AK. Cycloguanil pamoate in the treatment and suppression of malaria in the Gambia, West Africa. BMJ. 1966;1:695-701.
    • (1966) BMJ. , vol.1 , pp. 695-701
    • McGregor, I.A.1    Williams, K.2    Walker, G.H.3    Rahman, A.K.4
  • 143
    • 84884955494 scopus 로고    scopus 로고
    • Benzathine penicillin G for the management of RHD: Concerns about quality and access, and opportunities for intervention and improvement
    • 25690500
    • Wyber R, Taubert K, Marko S, Kaplan EL. Benzathine penicillin G for the management of RHD: concerns about quality and access, and opportunities for intervention and improvement. Glob Heart. 2013;8:227-34.
    • (2013) Glob Heart. , vol.8 , pp. 227-234
    • Wyber, R.1    Taubert, K.2    Marko, S.3    Kaplan, E.L.4
  • 144
    • 84995578513 scopus 로고    scopus 로고
    • An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia
    • 27784313 5081959
    • Leang R, Khu NH, Mukaka M, Debackere M, Tripura R, Kheang ST, et al. An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia. BMC Med. 2016;14:171.
    • (2016) BMC Med , vol.14 , pp. 171
    • Leang, R.1    Khu, N.H.2    Mukaka, M.3    Debackere, M.4    Tripura, R.5    Kheang, S.T.6
  • 145
    • 84870436534 scopus 로고    scopus 로고
    • Mosquito transmission of the rodent malaria parasite Plasmodium chabaudi
    • 23217144 3528485
    • Spence PJ, Jarra W, Levy P, Nahrendorf W, Langhorne J. Mosquito transmission of the rodent malaria parasite Plasmodium chabaudi. Malar J. 2012;11:407.
    • (2012) Malar J. , vol.11 , pp. 407
    • Spence, P.J.1    Jarra, W.2    Levy, P.3    Nahrendorf, W.4    Langhorne, J.5
  • 146
    • 84959473542 scopus 로고    scopus 로고
    • High-throughput assay and discovery of small molecules that interrupt malaria transmission
    • 1:CAS:528:DC%2BC28XhtlKrsQ%3D%3D 26749441 4723716
    • Plouffe DM, Wree M, Du AY, Meister S, Li F, Patra K, et al. High-throughput assay and discovery of small molecules that interrupt malaria transmission. Cell Host Microbe. 2016;19:114-26.
    • (2016) Cell Host Microbe , vol.19 , pp. 114-126
    • Plouffe, D.M.1    Wree, M.2    Du, A.Y.3    Meister, S.4    Li, F.5    Patra, K.6
  • 147
    • 84946721121 scopus 로고    scopus 로고
    • A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds
    • 1:CAS:528:DC%2BC2MXhvVWmsrvF 26553647 4639769
    • Lucantoni L, Silvestrini F, Signore M, Siciliano G, Eldering M, Dechering KJ, et al. A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds. Sci Rep. 2015;5:16414.
    • (2015) Sci Rep. , vol.5 , pp. 16414
    • Lucantoni, L.1    Silvestrini, F.2    Signore, M.3    Siciliano, G.4    Eldering, M.5    Dechering, K.J.6
  • 148
    • 85009466919 scopus 로고    scopus 로고
    • Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions
    • 1:CAS:528:DC%2BC28XhsVCgsb%2FL 27560172
    • Delves MJ, Straschil U, Ruecker A, Miguel-Blanco C, Marques S, Baum J, et al. Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions. Nat Protoc. 2016;11:1668-80.
    • (2016) Nat Protoc , vol.11 , pp. 1668-1680
    • Delves, M.J.1    Straschil, U.2    Ruecker, A.3    Miguel-Blanco, C.4    Marques, S.5    Baum, J.6
  • 149
    • 84951310501 scopus 로고    scopus 로고
    • A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes
    • 1:CAS:528:DC%2BC2MXitVygtb%2FL 26687564 4685452
    • Vos MW, Stone WJ, Koolen KM, van Gemert GJ, van Schaijk B, Leroy D, et al. A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes. Sci Rep. 2015;5:18704.
    • (2015) Sci Rep. , vol.5 , pp. 18704
    • Vos, M.W.1    Stone, W.J.2    Koolen, K.M.3    Van Gemert, G.J.4    Van Schaijk, B.5    Leroy, D.6
  • 150
    • 84943338940 scopus 로고    scopus 로고
    • A new set of chemical starting points with Plasmodium falciparum transmission-blocking potential for antimalarial drug discovery
    • 26317851 4552634
    • Almela MJ, Lozano S, Lelievre J, Colmenarejo G, Coteron JM, Rodrigues J, et al. A new set of chemical starting points with Plasmodium falciparum transmission-blocking potential for antimalarial drug discovery. PLoS ONE. 2015;10:e0135139.
    • (2015) PLoS ONE , vol.10 , pp. e0135139
    • Almela, M.J.1    Lozano, S.2    Lelievre, J.3    Colmenarejo, G.4    Coteron, J.M.5    Rodrigues, J.6
  • 151
    • 84879022516 scopus 로고    scopus 로고
    • Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs
    • 1:CAS:528:DC%2BC3sXhtVartrfF 23629698 3697345
    • Delves MJ, Ruecker A, Straschil U, Lelievre J, Marques S, Lopez-Barragan MJ, et al. Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs. Antimicrob Agents Chemother. 2013;57:3268-74.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 3268-3274
    • Delves, M.J.1    Ruecker, A.2    Straschil, U.3    Lelievre, J.4    Marques, S.5    Lopez-Barragan, M.J.6
  • 152
    • 84857769077 scopus 로고    scopus 로고
    • The activities of current antimalarial drugs on the life cycle stages of Plasmodium: A comparative study with human and rodent parasites
    • 22363211 3283556
    • Delves M, Plouffe D, Scheurer C, Meister S, Wittlin S, Winzeler EA, et al. The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites. PLoS Med. 2012;9:e1001169.
    • (2012) PLoS Med. , vol.9 , pp. e1001169
    • Delves, M.1    Plouffe, D.2    Scheurer, C.3    Meister, S.4    Wittlin, S.5    Winzeler, E.A.6
  • 153
    • 84904783240 scopus 로고    scopus 로고
    • A review of the effects of artemether-lumefantrine on gametocyte carriage and disease transmission
    • 25069530 4126813
    • Makanga M. A review of the effects of artemether-lumefantrine on gametocyte carriage and disease transmission. Malar J. 2014;13:291.
    • (2014) Malar J. , vol.13 , pp. 291
    • Makanga, M.1
  • 154
    • 79960881361 scopus 로고    scopus 로고
    • Community screening and treatment of asymptomatic carriers of Plasmodium falciparum with artemether-lumefantrine to reduce malaria disease burden: A modelling and simulation analysis
    • 21801345 3161019
    • Kern SE, Tiono AB, Makanga M, Gbadoe AD, Premji Z, Gaye O, et al. Community screening and treatment of asymptomatic carriers of Plasmodium falciparum with artemether-lumefantrine to reduce malaria disease burden: a modelling and simulation analysis. Malar J. 2011;10:210.
    • (2011) Malar J. , vol.10 , pp. 210
    • Kern, S.E.1    Tiono, A.B.2    Makanga, M.3    Gbadoe, A.D.4    Premji, Z.5    Gaye, O.6
  • 155
    • 77649289117 scopus 로고    scopus 로고
    • Treatment of asymptomatic carriers with artemether-lumefantrine: An opportunity to reduce the burden of malaria?
    • 20096111 2824802
    • Ogutu B, Tiono AB, Makanga M, Premji Z, Gbadoe AD, Ubben D, et al. Treatment of asymptomatic carriers with artemether-lumefantrine: an opportunity to reduce the burden of malaria? Malar J. 2010;9:30.
    • (2010) Malar J. , vol.9 , pp. 30
    • Ogutu, B.1    Tiono, A.B.2    Makanga, M.3    Premji, Z.4    Gbadoe, A.D.5    Ubben, D.6
  • 156
    • 84908555579 scopus 로고    scopus 로고
    • Development of a transmission-blocking malaria vaccine: Progress, challenges, and the path forward
    • 25077422
    • Nunes JK, Woods C, Carter T, Raphael T, Morin MJ, Diallo D, et al. Development of a transmission-blocking malaria vaccine: progress, challenges, and the path forward. Vaccine. 2014;32:5531-9.
    • (2014) Vaccine. , vol.32 , pp. 5531-5539
    • Nunes, J.K.1    Woods, C.2    Carter, T.3    Raphael, T.4    Morin, M.J.5    Diallo, D.6
  • 157
    • 84874254076 scopus 로고    scopus 로고
    • A controlled, parallel, cluster-randomized trial of community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso
    • 23442748 3599538
    • Tiono AB, Ouedraogo A, Ogutu B, Diarra A, Coulibaly S, Gansane A, et al. A controlled, parallel, cluster-randomized trial of community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso. Malar J. 2013;12:79.
    • (2013) Malar J. , vol.12 , pp. 79
    • Tiono, A.B.1    Ouedraogo, A.2    Ogutu, B.3    Diarra, A.4    Coulibaly, S.5    Gansane, A.6
  • 159
    • 84922433986 scopus 로고    scopus 로고
    • Efficacy and safety of the mosquitocidal drug ivermectin to prevent malaria transmission after treatment: A double-blind, randomized, clinical trial
    • 25414262
    • Ouédraogo AL, Bastiaens GJ, Tiono AB, Guelbeogo WM, Kobylinski KC, Ouedraogo A, et al. Efficacy and safety of the mosquitocidal drug ivermectin to prevent malaria transmission after treatment: a double-blind, randomized, clinical trial. Clin Infect Dis. 2015;60:357-65.
    • (2015) Clin Infect Dis , vol.60 , pp. 357-365
    • Ouédraogo, A.L.1    Bastiaens, G.J.2    Tiono, A.B.3    Guelbeogo, W.M.4    Kobylinski, K.C.5    Ouedraogo, A.6
  • 160
    • 73949129311 scopus 로고    scopus 로고
    • Chlorproguanil-dapsone-artesunate versus chlorproguanil-dapsone: A randomized, double-blind, phase III trial in African children, adolescents, and adults with uncomplicated Plasmodium falciparum malaria
    • 1:CAS:528:DC%2BC3cXlsFygtw%3D%3D 19996424
    • Tiono AB, Dicko A, Ndububa DA, Agbenyega T, Pitmang S, Awobusuyi J, et al. Chlorproguanil-dapsone-artesunate versus chlorproguanil-dapsone: a randomized, double-blind, phase III trial in African children, adolescents, and adults with uncomplicated Plasmodium falciparum malaria. Am J Trop Med Hyg. 2009;81:969-78.
    • (2009) Am J Trop Med Hyg , vol.81 , pp. 969-978
    • Tiono, A.B.1    Dicko, A.2    Ndububa, D.A.3    Agbenyega, T.4    Pitmang, S.5    Awobusuyi, J.6
  • 161
    • 68949200963 scopus 로고    scopus 로고
    • Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: A randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria
    • 19690618 2724683
    • Premji Z, Umeh RE, Owusu-Agyei S, Esamai F, Ezedinachi EU, Oguche S, et al. Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria. PLoS ONE. 2009;4:e6682.
    • (2009) PLoS ONE , vol.4 , pp. e6682
    • Premji, Z.1    Umeh, R.E.2    Owusu-Agyei, S.3    Esamai, F.4    Ezedinachi, E.U.5    Oguche, S.6
  • 163
    • 84941654269 scopus 로고    scopus 로고
    • High antimalarial efficacy of dihydroartemisinin-piperaquine on the China-Myanmar border: The calm before the storm
    • 26283745 4559676
    • Fairhurst RM. High antimalarial efficacy of dihydroartemisinin-piperaquine on the China-Myanmar border: the calm before the storm. Am J Trop Med Hyg. 2015;93:436-7.
    • (2015) Am J Trop Med Hyg. , vol.93 , pp. 436-437
    • Fairhurst, R.M.1
  • 165
    • 77958086412 scopus 로고    scopus 로고
    • Artemisinin-induced dormancy in Plasmodium falciparum: Duration, recovery rates, and implications in treatment failure
    • 20863228 2949454
    • Teuscher F, Gatton ML, Chen N, Peters J, Kyle DE, Cheng Q. Artemisinin-induced dormancy in Plasmodium falciparum: duration, recovery rates, and implications in treatment failure. J Infect Dis. 2010;202:1362-8.
    • (2010) J Infect Dis , vol.202 , pp. 1362-1368
    • Teuscher, F.1    Gatton, M.L.2    Chen, N.3    Peters, J.4    Kyle, D.E.5    Cheng, Q.6
  • 166
    • 77958108347 scopus 로고    scopus 로고
    • Waking the sleeping beauty
    • 20863226 3438230
    • Nosten F. Waking the sleeping beauty. J Infect Dis. 2010;202:1300-1.
    • (2010) J Infect Dis , vol.202 , pp. 1300-1301
    • Nosten, F.1
  • 167
    • 84934439985 scopus 로고    scopus 로고
    • An analysis of the attrition of drug candidates from four major pharmaceutical companies
    • 1:CAS:528:DC%2BC2MXhtFeju7jM 26091267
    • Waring MJ, Arrowsmith J, Leach AR, Leeson PD, Mandrell S, Owen RM, et al. An analysis of the attrition of drug candidates from four major pharmaceutical companies. Nat Rev Drug Discov. 2015;14:475-86.
    • (2015) Nat Rev Drug Discov. , vol.14 , pp. 475-486
    • Waring, M.J.1    Arrowsmith, J.2    Leach, A.R.3    Leeson, P.D.4    Mandrell, S.5    Owen, R.M.6
  • 168
    • 84979623010 scopus 로고    scopus 로고
    • Anti-malarial benzoxaboroles target P. falciparum leucyl-tRNA synthetase
    • 1:CAS:528:DC%2BC28Xhsl2jsbzM 27270277
    • Sonoiki E, Palencia A, Guo D, Ahyong V, Dong C, Li X, et al. Anti-malarial benzoxaboroles target P. falciparum leucyl-tRNA synthetase. Antimicrob Agents Chemother. 2016;60:4886-95.
    • (2016) Antimicrob Agents Chemother , vol.60 , pp. 4886-4895
    • Sonoiki, E.1    Palencia, A.2    Guo, D.3    Ahyong, V.4    Dong, C.5    Li, X.6
  • 169
    • 79955399200 scopus 로고    scopus 로고
    • A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling
    • 1:CAS:528:DC%2BC3MXksVKhs74%3D 21438569 3082593
    • Zhang B, Watts KM, Hodge D, Kemp LM, Hunstad DA, Hicks LM, et al. A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling. Biochemistry. 2011;50:3570-7.
    • (2011) Biochemistry , vol.50 , pp. 3570-3577
    • Zhang, B.1    Watts, K.M.2    Hodge, D.3    Kemp, L.M.4    Hunstad, D.A.5    Hicks, L.M.6
  • 173
    • 84947923897 scopus 로고    scopus 로고
    • In silico screening for identification of novel anti-malarial inhibitors by molecular docking, pharmacophore modeling and virtual screening
    • 1:CAS:528:DC%2BC2MXhsF2rsrjI 25741881
    • Batool S, Khan ZA, Kamal W, Mushtaq G, Kamal MA. In silico screening for identification of novel anti-malarial inhibitors by molecular docking, pharmacophore modeling and virtual screening. Med Chem. 2015;11:687-700.
    • (2015) Med Chem , vol.11 , pp. 687-700
    • Batool, S.1    Khan, Z.A.2    Kamal, W.3    Mushtaq, G.4    Kamal, M.A.5
  • 174
    • 84906079854 scopus 로고    scopus 로고
    • KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment and prevention of disease transmission
    • 24913172 4135840
    • Kuhen KL, Chatterjee AK, Rottmann M, Gagaring K, Borboa R, Buenviaje J, et al. KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment and prevention of disease transmission. Antimicrob Agents Chemother. 2014;58:5060-7.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 5060-5067
    • Kuhen, K.L.1    Chatterjee, A.K.2    Rottmann, M.3    Gagaring, K.4    Borboa, R.5    Buenviaje, J.6
  • 175
    • 85009490408 scopus 로고    scopus 로고
    • From Aspiration to Action
    • From Aspiration to Action. What will it take to end malaria? http://www.endmalaria2040.org/. 2016. p. 1-31.
    • (2016) What Will It Take to End Malaria? , pp. 1-31


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.