Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures

Nature Medicine

Volumn 20, Issue 3, 2014, Pages 307-312

  Dembélé, Laurent ^a,b   Franetich, Jean François ^a,b   Lorthiois, Audrey ^a,b   Gego, Audrey ^a,b   Zeeman, Anne Marie ^c   Kocken, Clemens H M ^c   Le Grand, Roger ^d,e   Dereuddre Bosquet, Nathalie ^d,e   Van Gemert, Geert Jan ^f   Sauerwein, Robert ^f   Vaillant, Jean Christophe ^g   Hannoun, Laurent ^g   Fuchter, Matthew J ^h   Diagana, Thierry T ⁱ   Malmquist, Nicholas A ^j,k   Scherf, Artur ^j,k   Snounou, Georges ^a,b   Mazier, Dominique ^a,b,g  

^a SORBONNE UNIVERSITÉ   (France)

^b INSERM   (France)

^c BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

^d DIF   (France)

^e UNIVERSITÉ PARIS SACLAY   (France)

^f RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^g PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^h IMPERIAL COLLEGE LONDON   (United Kingdom)

ⁱ NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

^j INSTITUT PASTEUR   (France)

^k CNRS   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ATOVAQUONE; HISTONE; HISTONE METHYLTRANSFERASE; N (1 BENZYL 4 PIPERIDINYL) 2 (HEXAHYDRO 4 METHYL 1H 1,4 DIAZEPIN 1 YL) 6,7 DIMETHOXY 4 QUINAZOLINAMINE;

ANIMAL CELL; ARTICLE; CELL MATURATION; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; DORMANCY; ENZYME INHIBITION; EPIGENETICS; GENE EXPRESSION; HISTONE METHYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HYPNOZOITE; IC 50; IN VITRO STUDY; LIVER CELL; LIVER CELL CULTURE; MACACA FASCICULARIS; MALARIA; MOLECULAR BIOLOGY; NONHUMAN; PLASMODIUM; PLASMODIUM CYNOMOLGI; PRIORITY JOURNAL; SPOROZOITE;

MACACA; MACACA FASCICULARIS; PLASMODIUM CYNOMOLGI; PLASMODIUM OVALE; PLASMODIUM VIVAX;

ANIMALS; CELL LINE; CELLS, CULTURED; EPIGENESIS, GENETIC; FEMALE; GREEN FLUORESCENT PROTEINS; HEPATOCYTES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; MACACA; MALARIA; MALE; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; PLASMODIUM CYNOMOLGI; RECURRENCE; SPOROZOITES; TIME FACTORS;

EID: 84896134875     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3461     Document Type: Article

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