Helping Chemists Discover New Antibiotics

ACS Infectious Diseases

Volumn 1, Issue 7, 2016, Pages 285-287

  Blaskovich, Mark A T ^a   Zuegg, Johannes ^a   Elliott, Alysha G ^a   Cooper, Matthew A ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT;

DRUG SCREENING; FOLLOW UP; MEDICAL RESEARCH; PRIORITY JOURNAL; SHORT SURVEY; VALIDATION STUDY;

EID: 84969246371     PISSN: None     EISSN: 23738227     Source Type: Journal    
DOI: 10.1021/acsinfecdis.5b00044     Document Type: Short Survey

References (8)

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2. Antibiotic Resistance Threats in the United States, 2013; U.S. Departmentof Health and Human Services, Centers for Disease Control and Prevention, (2013; pp 1-114; http://www.cdc.gov/drugresistance/threat-report-2013.
3. Davies, S. C. Chief Medical Officer Annual Report: Volume 2; https://www.gov.uk/government/publications/chief-medical-officer-annual-report-volume-2.
4. National Action Plan for Combating Antibiotic-Resistant Bacteria, March 2015; https://www.whitehouse.gov/sites/default/files/docs/national-action-plan-for-combating-antibotic-resistant-bacteria.pdf.
5. Ling, L. L., Schneider, T., Peoples, A. J., Spoering, A. L., Engels, I., Conlon, B. P., Mueller, A., Schäberle, T. F., Hughes, D. E., Epstein, S., Jones, M., Lazarides, L., Steadman, V. A., Cohen, D. R., Felix, C. R., Fetterman, K. A., Millett, W. P., Nitti, A. G., Zullo, A. M., Chen, C., and Lewis, K. (2015) A new antibiotic kills pathogens without detectable resistance Nature 517, 455-459 10.1038/nature14098
6. Lipinski, C. A., Lombardo, F., Dominy, B. W., and Feeney, P. J. (1997) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings Adv. Drug Delivery Rev. 23, 3-25 10.1016/S0169-409X(96)00423-1
7. Payne, D. J., Gwynn, M. N., Holmes, D. J., and Pompliano, D. L. (2007) Drugs for bad bugs: confronting the challenges of antibacterial discovery Nat. Rev. Drug Discovery 6, 29-40 10.1038/nrd2201
8. O'Shea, R. and Moser, H. E. (2008) Physicochemical properties of antibacterial compounds: implications for drug discovery J. Med. Chem. 51, 2871-2878 10.1021/jm700967e