-
1
-
-
84923534385
-
-
World Health Organization, Geneva, Switzerland
-
World Health Organization. 2014. Malaria fact sheet no. 94, World Health Organization, Geneva, Switzerland. http://www.who.int/mediacentre/factsheets/fs094/en.
-
(2014)
Malaria Fact Sheet No. 94
-
-
-
3
-
-
84904892931
-
Spread of artemisinin resistance in Plasmodium falciparum malaria
-
Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, Sreng S, Anderson JM, Mao S, Sam B, Sopha C, Chuor CM, Nguon C, Sovannaroth S, Pukrittayakamee S, Jittamala P, Chotivanich K, Chutasmit K, Suchatsoonthorn C, Runcharoen R, Hien TT, Thuy-Nhien NT, Thanh NV, Phu NH, Htut Y, Han KT, Aye KH, Mokuolu OA, Olaosebikan RR, Folaranmi OO, Mayxay M, Khanthavong M, Hongvanthong B, Newton PN, Onyamboko MA, Fanello CI, Tshefu AK, Mishra N, Valecha N, Phyo AP, Nosten F, Yi P, Tripura R, Borrmann S, Bashraheil M, Peshu J, Faiz MA, Ghose A, Hossain MA, Samad R, Rahman MR, Hasan MM, Islam A, Miotto O, Amato R, MacInnis B, Stalker J, Kwiatkowski DP, Bozdech Z, Jeeyapant A, Cheah PY, Sakulthaew T, Chalk J, Intharabut B, Silamut K, Lee SJ, Vihokhern B, Kunasol C, Imwong M, Tarning J, Taylor WJ, Yeung S, Woodrow CJ, Flegg JA, Das D, Smith J, Venkatesan M, Plowe CV, Stepniewska K, Guerin PJ, Dondorp AM, Day NP, White NJ, Tracking Resistance to Artemisinin Collaboration. 2014. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med 371:411-423. http://dx.doi.org/10.1056/NEJMoa1314981.
-
(2014)
N Engl J Med
, vol.371
, pp. 411-423
-
-
Ashley, E.A.1
Dhorda, M.2
Fairhurst, R.M.3
Amaratunga, C.4
Lim, P.5
Suon, S.6
Sreng, S.7
Anderson, J.M.8
Mao, S.9
Sam, B.10
Sopha, C.11
Chuor, C.M.12
Nguon, C.13
Sovannaroth, S.14
Pukrittayakamee, S.15
Jittamala, P.16
Chotivanich, K.17
Chutasmit, K.18
Suchatsoonthorn, C.19
Runcharoen, R.20
Hien, T.T.21
Thuy-Nhien, N.T.22
Thanh, N.V.23
Phu, N.H.24
Htut, Y.25
Han, K.T.26
Aye, K.H.27
Mokuolu, O.A.28
Olaosebikan, R.R.29
Folaranmi, O.O.30
Mayxay, M.31
Khanthavong, M.32
Hongvanthong, B.33
Newton, P.N.34
Onyamboko, M.A.35
Fanello, C.I.36
Tshefu, A.K.37
Mishra, N.38
Valecha, N.39
Phyo, A.P.40
Nosten, F.41
Yi, P.42
Tripura, R.43
Borrmann, S.44
Bashraheil, M.45
Peshu, J.46
Faiz, M.A.47
Ghose, A.48
Hossain, M.A.49
Samad, R.50
Rahman, M.R.51
Hasan, M.M.52
Islam, A.53
Miotto, O.54
Amato, R.55
MacInnis, B.56
Stalker, J.57
Kwiatkowski, D.P.58
Bozdech, Z.59
Jeeyapant, A.60
Cheah, P.Y.61
Sakulthaew, T.62
Chalk, J.63
Intharabut, B.64
Silamut, K.65
Lee, S.J.66
Vihokhern, B.67
Kunasol, C.68
Imwong, M.69
Tarning, J.70
Taylor, W.J.71
Yeung, S.72
Woodrow, C.J.73
Flegg, J.A.74
Das, D.75
Smith, J.76
Venkatesan, M.77
Plowe, C.V.78
Stepniewska, K.79
Guerin, P.J.80
Dondorp, A.M.81
Day, N.P.82
White, N.J.83
more..
-
4
-
-
77956280420
-
Spiroindolones, a potent compound class for the treatment of malaria
-
Rottmann M, McNamara C, Yeung BK, Lee MC, Zou B, Russell B, Seitz P, Plouffe DM, Dharia NV, Tan J, Cohen SB, Spencer KR, Gonzalez- Paez GE, Lakshminarayana SB, Goh A, Suwanarusk R, Jegla T, Schmitt EK, Beck HP, Brun R, Nosten F, Renia L, Dartois V, Keller TH, Fidock DA, Winzeler EA, Diagana TT. 2010. Spiroindolones, a potent compound class for the treatment of malaria. Science 329:1175-1180. http://dx.doi.org/10.1126/science.1193225.
-
(2010)
Science
, vol.329
, pp. 1175-1180
-
-
Rottmann, M.1
McNamara, C.2
Yeung, B.K.3
Lee, M.C.4
Zou, B.5
Russell, B.6
Seitz, P.7
Plouffe, D.M.8
Dharia, N.V.9
Tan, J.10
Cohen, S.B.11
Spencer, K.R.12
Gonzalez- Paez, G.E.13
Lakshminarayana, S.B.14
Goh, A.15
Suwanarusk, R.16
Jegla, T.17
Schmitt, E.K.18
Beck, H.P.19
Brun, R.20
Nosten, F.21
Renia, L.22
Dartois, V.23
Keller, T.H.24
Fidock, D.A.25
Winzeler, E.A.26
Diagana, T.T.27
more..
-
5
-
-
77954745330
-
Spirotetrahydro β-carbolines (spiroindolones): A new class of potent and orally efficacious compounds for the treatment of malaria
-
Yeung BK, Zou B, Rottmann M, Lakshminarayana SB, Ang SH, Leong SY, Tan J, Wong J, Keller-Maerki S, Fischli C, Goh A, Schmitt EK, Krastel P, Francotte E, Kuhen K, Plouffe D, Henson K, Wagner T, Winzeler EA, Petersen F, Brun R, Dartois V, Diagana TT, Keller TH. 2010. Spirotetrahydro β-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria. J Med Chem 53:5155-5164. http://dx.doi.org/10.1021/jm100410f.
-
(2010)
J Med Chem
, vol.53
, pp. 5155-5164
-
-
Yeung, B.K.1
Zou, B.2
Rottmann, M.3
Lakshminarayana, S.B.4
Ang, S.H.5
Leong, S.Y.6
Tan, J.7
Wong, J.8
Keller-Maerki, S.9
Fischli, C.10
Goh, A.11
Schmitt, E.K.12
Krastel, P.13
Francotte, E.14
Kuhen, K.15
Plouffe, D.16
Henson, K.17
Wagner, T.18
Winzeler, E.A.19
Petersen, F.20
Brun, R.21
Dartois, V.22
Diagana, T.T.23
Keller, T.H.24
more..
-
6
-
-
84907916563
-
A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel antimalarial spiroindolone KAE609 (cipargamin) to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers
-
Leong FJ, Li R, Jain JP, Lefevre G, Magnusson B, Diagana TT, Pertel P. 2014. A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel antimalarial spiroindolone KAE609 (cipargamin) to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers. Antimicrob Agents Chemother 58:6209-6214. http://dx.doi.org/10.1128/AAC.03393-14.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 6209-6214
-
-
Leong, F.J.1
Li, R.2
Jain, J.P.3
Lefevre, G.4
Magnusson, B.5
Diagana, T.T.6
Pertel, P.7
-
7
-
-
84904909454
-
Spiroindolone KAE609 for falciparum and vivax malaria
-
White NJ, Pukrittayakamee S, Phyo AP, Rueangweerayut R, Nosten F, Jittamala P, Jeeyapant A, Jain JP, Lefevre G, Li R, Magnusson B, Diagana TT, Leong FJ. 2014. Spiroindolone KAE609 for falciparum and vivax malaria. N Engl J Med 371:403-410. http://dx.doi.org/10.1056/NEJMoa1315860.
-
(2014)
N Engl J Med
, vol.371
, pp. 403-410
-
-
White, N.J.1
Pukrittayakamee, S.2
Phyo, A.P.3
Rueangweerayut, R.4
Nosten, F.5
Jittamala, P.6
Jeeyapant, A.7
Jain, J.P.8
Lefevre, G.9
Li, R.10
Magnusson, B.11
Diagana, T.T.12
Leong, F.J.13
-
8
-
-
84879601438
-
Efficacy and safety of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum malaria in endemic countries: Meta-analysis of randomised controlled studies
-
Naing C, Mak JW, Aung K, Wong JY. 2013. Efficacy and safety of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum malaria in endemic countries: meta-analysis of randomised controlled studies. Trans R Soc Trop Med Hyg 107:65-73. http://dx.doi.org/10.1093/trstmh/trs019.
-
(2013)
Trans R Soc Trop Med Hyg
, vol.107
, pp. 65-73
-
-
Naing, C.1
Mak, J.W.2
Aung, K.3
Wong, J.Y.4
-
9
-
-
77952118055
-
-
European Medicines Agency European Medicines Agency, London, United Kingdom
-
European Medicines Agency. 2014. Eurartesim: summary of product characteristics. European Medicines Agency, London, United Kingdom. http://www.ema.europa.eu/docs/en-GB/document-library/EPAR-Product-Information/human/001199/WC500118113.pdf.
-
(2014)
Eurartesim: Summary of Product Characteristics
-
-
-
10
-
-
84907914805
-
Randomized, double-blind, placebo-controlled clinical trial of a two-day regimen of dihydroartemisinin-piperaquine for malaria prevention halted for concern over prolonged corrected QT interval
-
Manning J, Vanachayangkul P, Lon C, Spring M, So M, Sea D, Se Y, Somethy S, Phann ST, Chann S, Sriwichai S, Buathong N, Kuntawunginn W, Mitprasat M, Siripokasupkul R, Teja-Isavadharm P, Soh E, Timmermans A, Lanteri C, Kaewkungwal J, Auayporn M, Tang D, Chour CM, Prom S, Haigney M, Cantilena L, Saunders D. 2014. Randomized, double-blind, placebo-controlled clinical trial of a two-day regimen of dihydroartemisinin-piperaquine for malaria prevention halted for concern over prolonged corrected QT interval. Antimicrob Agents Chemother 58:6056-6067. http://dx.doi.org/10.1128/AAC.02667-14.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 6056-6067
-
-
Manning, J.1
Vanachayangkul, P.2
Lon, C.3
Spring, M.4
So, M.5
Sea, D.6
Se, Y.7
Somethy, S.8
Phann, S.T.9
Chann, S.10
Sriwichai, S.11
Buathong, N.12
Kuntawunginn, W.13
Mitprasat, M.14
Siripokasupkul, R.15
Teja-Isavadharm, P.16
Soh, E.17
Timmermans, A.18
Lanteri, C.19
Kaewkungwal, J.20
Auayporn, M.21
Tang, D.22
Chour, C.M.23
Prom, S.24
Haigney, M.25
Cantilena, L.26
Saunders, D.27
more..
|