High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission

Cell Host and Microbe

Volumn 19, Issue 1, 2016, Pages 114-126

  Plouffe, David M ^a   Wree, Melanie ^b   Du, Alan Y ^b   Meister, Stephan ^b   Li, Fengwu ^c   Patra, Kailash ^c   Lubar, Aristea ^c   Okitsu, Shinji L ^b,g   Flannery, Erika L ^b   Kato, Nobutaka ^d   Tanaseichuk, Olga ^a   Comer, Eamon ^d   Zhou, Bin ^a   Kuhen, Kelli ^a   Zhou, Yingyao ^a   Leroy, Didier ^e   Schreiber, Stuart L ^d,f   Scherer, Christina A ^d   Vinetz, Joseph ^c   Winzeler, Elizabeth A ^b  

^a GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e Medicines for Malaria Venture MMV   (Switzerland)

^f HARVARD UNIVERSITY   (United States)

^g EMD Serono Research Institute   (United States)

Author keywords

chemotherapy; gametocytes; malaria; Plasmodium; transmission

Indexed keywords

AMODIAQUINE; ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISININ; ARTEROLANE; ARTESUNATE; AZITHROMYCIN; BENFLUMETOL; CHLOROQUINE; CHLORPROGUANIL; CLINDAMYCIN; DAPSONE; DIHYDROARTEMISININ; DOXYCYCLINE; FOSMIDOMYCIN; HALOFANTRINE; HYDROXYCHLOROQUINE; MEFLOQUINE; PAMAQUINE; PIPERAQUINE; PRIMAQUINE; PYRIMETHAMINE; PYRONARIDINE; QUINIDINE; QUININE SULFATE; TAFENOQUINE; TETRACYCLINE; THIOSTREPTON; TRIMETHOPRIM; UNINDEXED DRUG;

ARTICLE; CYST (RESTING STAGE); DRUG DETERMINATION; DRUG DEVELOPMENT; DRUG SYNTHESIS; GAMETOCYTE; GROWTH INHIBITION; HEPG2 CELL LINE; HIGH THROUGHPUT SCREENING; HUMAN; MALARIA; MALARIA CONTROL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SAPONIN LYSIS SEXUAL STAGE ASSAY; DRUG EFFECTS; EVALUATION STUDY; PARASITOLOGY; PHYSIOLOGY; PRECLINICAL STUDY; PROCEDURES; TRANSMISSION;

ANTIMALARIALS; DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MALARIA; PLASMODIUM FALCIPARUM;

EID: 84959473542     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2015.12.001     Document Type: Article

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