Adverse effects of falciparum and vivax malaria and the safety of antimalarial treatment in early pregnancy: A population-based study

The Lancet Infectious Diseases

Volumn 12, Issue 5, 2012, Pages 388-396

  McGready, R ^a,b,c   Lee, S J ^b,c   Wiladphaingern, J ^a   Ashley, E A ^a,b,c   Rijken, M J ^a   Boel, M ^a   Simpson, J A ^d   Paw, M K ^a   Pimanpanarak, M ^a   Mu, Oh ^a   Singhasivanon, P ^b   White, N J ^b,c   Nosten, F H ^a,b,c  

^a SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^b MAHIDOL OXFORD TROPICAL MEDICINE RESEARCH UNIT   (Thailand)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMETHER PLUS BENFLUMETOL; ARTEMISININ; ARTESUNATE; ATOVAQUONE PLUS PROGUANIL; CHLOROQUINE; CLINDAMYCIN; DOXYCYCLINE; MEFLOQUINE; QUININE;

ADULT; ARTICLE; BIRTH WEIGHT; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HIGH RISK PREGNANCY; HUMAN; MALARIA FALCIPARUM; MATERNAL AGE; MATERNAL SMOKING; MEDICAL RECORD; MONOTHERAPY; NONHUMAN; OUTCOME ASSESSMENT; PARASITEMIA; PLASMODIUM VIVAX MALARIA; PREGNANCY OUTCOME; PRIORITY JOURNAL; SIDE EFFECT; SPONTANEOUS ABORTION; UNSPECIFIED SIDE EFFECT;

ABORTION, SPONTANEOUS; ADOLESCENT; ADULT; ANTIMALARIALS; FEMALE; HUMANS; MALARIA, FALCIPARUM; MALARIA, VIVAX; MIDDLE AGED; MYANMAR; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; PREGNANCY OUTCOME; PREGNANCY TRIMESTER, FIRST; RETROSPECTIVE STUDIES; THAILAND; YOUNG ADULT;

EID: 84860295622     PISSN: 14733099     EISSN: 14744457     Source Type: Journal    
DOI: 10.1016/S1473-3099(11)70339-5     Document Type: Article

References (36)

1. Dellicour S, Hall S, Chandramohan D, Greenwood B The safety of artemisinins during pregnancy: a pressing question. Malar J 2007, 6:15.
2. Dellicour S, Tatem AJ, Guerra CA, Snow RW, ter Kuile FO Quantifying the number of pregnancies at risk of malaria in 2007: a demographic study. PLoS Med 2010, 7:e1000221.
3. Goldkind SF, Sahin L, Gallauresi B Enrolling pregnant women in research-lessons from the H1N1 influenza pandemic. N Engl J Med 2010, 362:2241.
4. Guidelines for the treatment of malaria 2010, WHO, WHO, Geneva. 2nd edn.
5. Finaurini S, Ronzoni L, Colancecco A, et al. Selective toxicity of dihydroartemisinin on human CD34+ erythroid cell differentiation. Toxicology 2010, 276:128-134.
6. Clark RL, Arima A, Makori N, et al. Artesunate: developmental toxicity and toxicokinetics in monkeys. Birth Defects Res B Dev Reprod Toxicol 2008, 83:418-434.
7. Chen LJ, Wang MY, Sun WK, Liu MZ [Embryotoxicity and teratogenicity studies on artemether in mice, rats and rabbits]. Zhongguo Yao Li Xue Bao 1984, 5:118-122.
8. Longo M, Zanoncelli S, Torre PD, et al. In vivo and in vitro investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos. Reprod Toxicol 2006, 22:797-810.
9. White TE, Clark RL Sensitive periods for developmental toxicity of orally administered artesunate in the rat. Birth Defects Res B Dev Reprod Toxicol 2008, 83:407-417.
10. Luxemburger C, Ricci F, Nosten F, Raimond D, Bathet S, White NJ The epidemiology of severe malaria in an area of low transmission in Thailand. Trans R Soc Trop Med Hyg 1997, 91:256-262.
11. Nosten F, McGready R, Simpson JA, et al. Effects of Plasmodium vivax malaria in pregnancy. Lancet 1999, 354:546-549.
12. Nosten F, ter Kuile F, Maelankirri L, Decludt B, White NJ Malaria during pregnancy in an area of unstable endemicity. Trans R Soc Trop Med Hyg 1991, 85:424-429.
13. Dolan G, ter Kuile F, Jacoutot V, et al. Bed nets for the prevention of malaria and anaemia in pregnancy. Trans R Soc Trop Med Hyg 1993, 87:620-626.
14. McGready R, Simpson JA, Htway M, White NJ, Nosten F, Lindsay SW A double-blind randomized therapeutic trial of insect repellents for the prevention of malaria in pregnancy. Trans R Soc Trop Med Hyg 2001, 95:137-138.
15. Nosten F, ter Kuile F, Maelankiri L, et al. Mefloquine prophylaxis prevents malaria during pregnancy: a double-blind, placebo-controlled study. J Infect Dis 1994, 169:595-603.
16. McGready R, Nosten F The Thai-Burmese border: drug studies of Plasmodium falciparum in pregnancy. Ann Trop Med Parasitol 1999, 93(suppl 1):S19-S23.
17. Nosten F, van Vugt M, Price R, et al. Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: a prospective study. Lancet 2000, 356:297-302.
18. Luxemburger C, Nosten F, Raimond SD, Chongsuphajaisiddhi T, White NJ Oral artesunate in the treatment of uncomplicated hyperparasitemic falciparum malaria. Am J Trop Med Hyg 1995, 53:522-525.
19. McGready R, Cho T, Cho JJ, et al. Artemisinin derivatives in the treatment of falciparum malaria in pregnancy. Trans R Soc Trop Med Hyg 1998, 92:430-433.
20. McGready R, Cho T, Keo NK, et al. Artemisinin antimalarials in pregnancy: a prospective treatment study of 539 episodes of multidrug-resistant Plasmodium falciparum. Clin Infect Dis 2001, 33:2009-2016.
21. McGready R, Thwai KL, Cho T, et al. The effects of quinine and chloroquine antimalarial treatments in the first trimester of pregnancy. Trans R Soc Trop Med Hyg 2002, 96:180-184.
22. Rai R, Regan L Recurrent miscarriage. Lancet 2006, 368:601-611.
23. McGready R, Ashley EA, Wuthiekanun V, et al. Arthropod borne disease: the leading cause of fever in pregnancy on the Thai-Burmese border. PLoS Negl Trop Dis 2010, 4:e888.
24. Plewes K, Lee T, Kajeechewa L, et al. Low seroprevalence of HIV and syphilis in pregnant women in refugee camps on the Thai-Burma border. Int J STD AIDS 2008, 19:833-837.
25. Assessment and monitoring of antimalarial drug efficacy for the treatment of uncomplicated falciparum malaria 2003, WHO, WHO, Geneva.
26. Rijken M, Rijken J, Papageorghiou A, et al. Malaria in pregnancy: the difficulties in measuring birthweight. Br J Obs Gynaecol 2011, 118:671-678.
27. Rijken MJ, Lee SJ, Boel ME, et al. Obstetric ultrasound scanning by local health workers in a refugee camp on the Thai-Burmese border. Ultrasound Obstet Gynecol 2009, 34:395-403.
28. Dubowitz LM, Dubowitz V, Goldberg C Clinical assessment of gestational age in the newborn infant. J Pediatr 1970, 77:1-10.
29. White LJ, Lee SJ, Stepniewska K, et al. Estimation of gestational age from fundal height: a solution for resource-poor settings. J R Soc Interface 2011, published online Aug 17. 10.1098/rsif.2011.0376.
30. Brady A Adjusted population attributable fractions from logistic regression. Stata J 1988, 42:8-12.
31. Wang X, Chen C, Wang L, et al. Conception, early pregnancy loss, and time to clinical pregnancy: a population based prospective study. Fertil Stertil 2005, 79:577.
32. Edwards MJ Review: Hyperthermia and fever during pregnancy. Birth Defects Res 2006, 76:507-516.
33. Korrick SA, Chen C, Damokosh AI, et al. Association of DDT with spontaneous abortion: a case-control study. Ann Epidemiol 2001, 11:491-496.
34. Deen JL, von Seidlein L, Pinder M, Walraven GE, Greenwood BM The safety of the combination artesunate and pyrimethamine-sulfadoxine given during pregnancy. Trans R Soc Trop Med Hyg 2001, 95:424-428.
35. Manyando C, Mkandawire R, Puma L, et al. Safety of artemether-lumefantrine in pregnant women with malaria: results of a prospective cohort study in Zambia. Malar J 2010, 9:249.
36. Adam I, Elhassan EM, Omer EM, Abdulla MA, Mahgoub HM, Adam GK Safety of artemisinins during early pregnancy, assessed in 62 Sudanese women. Ann Trop Med Parasitol 2009, 103:205-210.