Safety and comparability of controlled human plasmodium falciparum infection by mosquito bite in malaria-naïve subjects at a new facility for sporozoite challenge

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Talley, Angela K ^a   Healy, Sara A ^b   Finney, Olivia C ^a   Murphy, Sean C ^c   Kublin, James ^d   Salas, Carola J ^e   Lundebjerg, Susan ^a   Gilbert, Peter ^d   Van Voorhis, Wesley C ^c   Whisler, John ^a   Wang, Ruobing ^a   Ockenhouse, Chris F ^f   Heppner, D Gray ^f   Kappe, Stefan H ^a   Duffy, Patrick E ^b  

^a SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^d USA   (United States)

^e Peru   (Peru)

^f WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CHLOROQUINE; CIRCUMSPOROZOITE PROTEIN; LIVER STAGE ANTIGEN 1; MALARIA VACCINE; MEROZOITE SURFACE PROTEIN 1; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ANOPHELES STEPHENSI; ANTIBODY PRODUCTION; ARTICLE; BLOOD SMEAR; CELLULAR IMMUNITY; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HUMAN; HUMORAL IMMUNITY; INFECTION CONTROL; MALARIA FALCIPARUM; MALE; MONITORING; MOSQUITO BITE; NONHUMAN; PARASITEMIA; PLASMODIUM FALCIPARUM; PROSPECTIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAFETY; SPOROZOITE; VOLUNTEER; ANIMAL; ANOPHELES; BITES AND STINGS; CLINICAL TRIAL; COMPLICATION; HUMAN EXPERIMENT; IMMUNOLOGY; MALARIA, FALCIPARUM; PARASITOLOGY; PATHOGENICITY; PHYSIOLOGY;

ANOPHELES STEPHENSI; PLASMODIUM FALCIPARUM;

ADULT; ANIMALS; ANOPHELES; BITES AND STINGS; FEMALE; HUMAN EXPERIMENTATION; HUMANS; MALARIA, FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; SPOROZOITES;

EID: 84914689866     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109654     Document Type: Article

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