Cellular aging towards osteoarthritis

Mechanisms of Ageing and Development

Volumn 162, Issue , 2017, Pages 80-84

  Li, Yu Sheng ^a   Xiao, Wen feng ^a   Luo, Wei ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Aging; Antioxidants; Chondrocyte dysfunction; Osteoarthritis

Indexed keywords

ASCORBIC ACID; COLLAGENASE 3; CURCUMIN; EPIDERMAL GROWTH FACTOR; HYDROXYPTEROSTILBENE; HYPOXIA INDUCIBLE FACTOR 2ALPHA; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; MICRORNA; MICRORNA 30B; MICRORNA 34A; NATURAL PRODUCT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PTEROSTILBENE; QUERCETIN; RESVERATROL; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; SIRTUIN 4; SIRTUIN 5; SIRTUIN 6; STROMELYSIN; THYMOQUINONE; TRANSFORMING GROWTH FACTOR BETA; TRICHOSTATIN A; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; AGGRECAN; COLLAGEN TYPE 2; CYTOKINE; REACTIVE OXYGEN METABOLITE;

ALZHEIMER DISEASE; ATHEROSCLEROSIS; AUTOPHAGY; CELL AGING; HUMAN; MALIGNANT NEOPLASM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OSTEOARTHRITIS; OXIDATIVE STRESS; REVIEW; SENESCENCE; AGING; ANIMAL; METABOLISM; PATHOLOGY;

AGGRECANS; AGING; ANIMALS; CELL AGING; COLLAGEN TYPE II; CYTOKINES; HUMANS; OSTEOARTHRITIS; REACTIVE OXYGEN SPECIES;

EID: 85008430269     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2016.12.012     Document Type: Review

References (64)

1. Ailixiding, M., Aibibula, Z., Iwata, M., Piao, J., Hara, Y., Koga, D., Okawa, A., Morita, S., Asou, Y., Pivotal role of Sirt6 in the crosstalk among ageing, metabolic syndrome and osteoarthritis. Biochem. Biophys. Res. Commun. 466 (2015), 319–326.
2. Benderdour, M., Martel-Pelletier, J., Pelletier, J.P., Kapoor, M., Zunzunegui, M.V., Fahmi, H., Cellular aging, senescence and autophagy processes in osteoarthritis. Curr. Aging Sci. 8 (2015), 147–157.
3. Bijlsma, J.W., Berenbaum, F., Lafeber, F.P., Osteoarthritis: an update with relevance for clinical practice. Lancet 377 (2011), 2115–2126.
4. Blander, G., Guarente, L., The Sir2 family of protein deacetylases. Annu. Rev. Biochem. 73 (2004), 417–435.
5. Brandt, K.D., Dieppe, P., Radin, E., Etiopathogenesis of osteoarthritis. Med. Clin. North Am. 93 (2009), 1–24 (xv).
6. Buttgereit, F., Burmester, G.R., Bijlsma, J.W., Non-surgical management of knee osteoarthritis: where are we now and where do we need to go?. RMD Open, 1, 2015, e000027.
7. Cai, D., Yin, S., Yang, J., Jiang, Q., Cao, W., Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis. Arthritis Res. Ther., 17, 2015, 269.
8. Caramés, B., Olmer, M., Kiosses, W.B., Lotz, M.K., The relationship of autophagy defects to cartilage damage during joint aging in a mouse model. Arthritis Rheumatol. 67 (2015), 1568–1576.
9. Chang, Z., Huo, L., Li, P., Wu, Y., Zhang, P., Ascorbic acid provides protection for human chondrocytes against oxidative stress. Mol. Med. Rep. 12 (2015), 7086–7092.
10. Chen, Z., Jin, T., Lu, Y., AntimiR-30b inhibits TNF-α mediated apoptosis and attenuated cartilage degradation through enhancing autophagy. Cell Physiol. Biochem. 40 (2016), 883–894.
11. Cheng, C., Gao, S., Lei, G., Association of osteopontin with osteoarthritis. Rheumatol. Int. 34 (2014), 1627–1631.
12. Chin, K.Y., The spice for joint inflammation: anti-inflammatory role of curcumin in treating osteoarthritis. Drug Des. Devel. Ther. 10 (2016), 3029–3042.
13. Collins, J.A., Wood, S.T., Nelson, K.J., Rowe, M.A., Carlson, C.S., Chubinskaya, S., Poole, L.B., Furdui, C.M., Loeser, R.F., Oxidative stress promotes peroxiredoxin hyperoxidation and attenuates pro-survival signaling in aging chondrocytes. J. Biol. Chem. 291 (2016), 6641–6654.
14. Dillin, A., Hsu, A.L., Arantes-Oliveira, N., Lehrer-Graiwer, J., Hsin, H., Fraser, A.G., Kamath, R.S., Ahringer, J., Kenyon, C., Rates of behavior and aging specified by mitochondrial function during development. Science 298 (2002), 2398–2401.
15. Fang, H., Beier, F., Mouse models of osteoarthritis: modeling risk factors and assessing outcomes. Nat. Rev. Rheumatol. 10 (2014), 413–421.
16. Feng, J., Bussière, F., Hekimi, S., Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans. Dev. Cell 1 (2001), 633–644.
17. Fontana, L., Partridge, L., Longo, V.D., Extending healthy life span–from yeast to humans. Science 328 (2010), 321–326.
18. Fransen, M., Bridgett, L., March, L., Hoy, D., Penserga, E., Brooks, P., The epidemiology of osteoarthritis in Asia. Int. J. Rheum. Dis. 14 (2011), 113–121.
19. Freitag, J., Bates, D., Boyd, R., Shah, K., Barnard, A., Huguenin, L., Tenen, A., Mesenchymal stem cell therapy in the treatment of osteoarthritis: reparative pathways, safety and efficacy − a review. BMC Musculoskelet. Disord., 17, 2016, 230.
20. Ghosh, H.S., McBurney, M., Robbins, P.D., SIRT1 negatively regulates the mammalian target of rapamycin. PLoS One, 5, 2010, e9199.
21. Glyn-Jones, S., Palmer, A.J., Agricola, R., Price, A.J., Vincent, T.L., Weinans, H., Carr, A.J., Osteoarthr. Lancet 386 (2015), 376–387.
22. Greene, M.A., Loeser, R.F., Aging-related inflammation in osteoarthritis. Osteoarthritis Cartilage 23 (2015), 1966–1971.
23. Hügle, T., Geurts, J., Nüesch, C., Müller-Gerbl, M., Valderrabano, V., Aging and osteoarthritis: an inevitable encounter?. J. Aging Res., 2012, 2012, 950192.
24. Imai, S., Guarente, L., Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases. Trends Pharmacol. Sci. 31 (2010), 212–220.
25. Johnson, S.C., Rabinovitch, P.S., Kaeberlein, M., mTOR is a key modulator of ageing and age-related disease. Nature 493 (2013), 338–345.
26. Jones, G., Osteoarthritis: where are we for pain and therapy in 2013?. Aust. Family Physician 42 (2013), 766–769.
27. Kenyon, C.J., The genetics of ageing. Nature 464 (2010), 504–512.
28. Kirkwood, T.B., Understanding the odd science of aging. Cell 120 (2005), 437–447.
29. Koike, M., Nojiri, H., Ozawa, Y., Watanabe, K., Muramatsu, Y., Kaneko, H., Morikawa, D., Kobayashi, K., Saita, Y., Sasho, T., Shirasawa, T., Yokote, K., Kaneko, K., Shimizu, T., Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration. Sci. Rep., 5, 2015, 11722.
30. López de Figueroa, P., Lotz, M.K., Blanco, F.J., Caramés, B., Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes. Arthritis Rheumatol. 67 (2015), 966–976.
31. Lee, S.S., Lee, R.Y., Fraser, A.G., Kamath, R.S., Ahringer, J., Ruvkun, G., A systematic RNAi screen identifies a critical role for mitochondria in C elegans longevity. Nat. Genet. 33 (2003), 40–48.
32. Li, W., Cai, L., Zhang, Y., Cui, L., Shen, G., Intra-articular resveratrol injection prevents osteoarthritis progression in a mouse model by activating SIRT1 and thereby silencing HIF-2α. J. Orthop. Res. 33 (2015), 1061–1070.
33. Liu, L., Gu, H., Liu, H., Jiao, Y., Li, K., Zhao, Y., An, L., Yang, J., Protective effect of resveratrol against IL-1β-induced inflammatory response on human osteoarthritic chondrocytes partly via the TLR4/MyD88/NF-κB signaling pathway: an in vitro study. Int. J. Mol. Sci. 15 (2014), 6925–6940.
34. Loeser, R.F., Collins, J.A., Diekman, B.O., Ageing and the pathogenesis of osteoarthritis. Nat. Rev. Rheumatol. 12 (2016), 412–420.
35. Loeser, R.F., Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix. Osteoarthr. Cartilage 17 (2009), 971–979.
36. Loeser, R.F., Aging and osteoarthritis. Curr. Opin. Rheumatol. 23 (2011), 492–496.
37. MacNee, W., Rabinovich, R.A., Choudhury, G., Ageing and the border between health and disease. Eur. Respir. J. 44 (2014), 1332–1352.
38. Martin, I., Jakob, M., Schäfer, D., Dick, W., Spagnoli, G., Heberer, M., Quantitative analysis of gene expression in human articular cartilage from normal and osteoarthritic joints. Osteoarthr. Cartilage 9 (2001), 112–118.
39. Niccoli, T., Partridge, L., Ageing as a risk factor for disease. Curr. Biol. 22 (2012), R741–R752.
40. Pérez Martín, Á., Symptoms. Localizations: knee hip, hands, spine, other localizations. Aten. Primaria 46 (2014), 11–17.
41. Piao, J., Tsuji, K., Ochi, H., Iwata, M., Koga, D., Okawa, A., Morita, S., Takeda, S., Asou, Y., Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling. Sci. Rep., 3, 2013, 3022.
42. Portal-Núñez, S., Esbrit, P., Alcaraz, M.J., Largo, R., Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis. Biochem. Pharmacol. 108 (2016), 1–10.
43. Ruiz, M., Cosenza, S., Maumus, M., Jorgensen, C., Noël, D., Therapeutic application of mesenchymal stem cells in osteoarthritis. Expert Opin. Biol. Ther. 16 (2016), 33–42.
44. Sacitharan, P.K., Vincent, T.L., Cellular ageing mechanisms in osteoarthritis. Mamm. Genome 27 (2016), 421–429.
45. Saito, T., Fukai, A., Mabuchi, A., Ikeda, T., Yano, F., Ohba, S., Nishida, N., Akune, T., Yoshimura, N., Nakagawa, T., Nakamura, K., Tokunaga, K., Chung, U.I., Kawaguchi, H., Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development. Nat. Med. 16 (2010), 678–686.
46. Shane Anderson, A., Loeser, R.F., Why is osteoarthritis an age-related disease?. Best Pract. Res. Clin. Rheumatol. 24 (2010), 15–26.
47. Shen, T., Alvarez-Garcia, O., Li, Y., Olmer, M., Lotz, M.K., Suppression of Sestrins in aging and osteoarthritic cartilage: dysfunction of an important stress defense mechanism. Osteoarthr. Cartilage, 2016 Epub ahead of print.
48. Siard, M.H., McMurry, K.E., Adams, A.A., Effects of polyphenols including curcuminoids, resveratrol, quercetin, pterostilbene, and hydroxypterostilbene on lymphocyte pro-inflammatory cytokine production of senior horses in vitro. Vet. Immunol. Immunopathol. 173 (2016), 50–59.
49. Stanfel, M.N., Shamieh, L.S., Kaeberlein, M., Kennedy, B.K., The TOR pathway comes of age. Biochim. Biophys. Acta 1790 (2009), 1067–1074.
50. Takayama, K., Ishida, K., Matsushita, T., Fujita, N., Hayashi, S., Sasaki, K., Tei, K., Kubo, S., Matsumoto, T., Fujioka, H., Kurosaka, M., Kuroda, R., SIRT1 regulation of apoptosis of human chondrocytes. Arthritis Rheum. 60 (2009), 2731–2740.
51. Taylor, R.C., Dillin, A., Aging as an event of proteostasis collapse. Cold Spring Harb. Perspect. Biol., 3, 2011 pii a004440.
52. Tee, A.R., Manning, B.D., Roux, P.P., Cantley, L.C., Blenis, J., Tuberous sclerosis complex gene products, Tuberin and Hamartin: control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. Curr. Biol. 13 (2003), 1259–1268.
53. Toh, W.S., Brittberg, M., Farr, J., Foldager, C.B., Gomoll, A.H., Hui, J.H., Richardson, J.B., Roberts, S., Spector, M., Cellular senescence in aging and osteoarthritis. Acta Orthop. 23 (2016), 1–9.
54. Vargas Negrín, F., Medina Abellán, M.D., Hermosa Hernán, J.C., de Felipe Medina, R., Treatment of patients with osteoarthritis. Aten. Primaria. 46 (2014), 39–61.
55. Wang, D., Qiao, J., Zhao, X., Chen, T., Guan, D., Thymoquinone inhibits IL-1β-Induced inflammation in human osteoarthritis chondrocytes by suppressing NF-κB and MAPKs signaling pathway. Inflammation 38 (2015), 2235–2241.
56. Wolff, S., Dillin, A., The trifecta of aging in Caenorhabditis elegans. Exp. Gerontol. 41 (2006), 894–903.
57. Woolf, A.D., Pfleger, B., Burden of major musculoskeletal conditions. Bull. World Health Organ. 81 (2003), 646–656.
58. Wu, Y., Chen, L., Wang, Y., Li, W., Lin, Y., Yu, D., Zhang, L., Li, F., Pan, Z., Overexpression of Sirtuin 6 suppresses cellular senescence and NF-(B mediated inflammatory responses in osteoarthritis development. Sci. Rep., 5, 2015, 17602.
59. Wyles, C.C., Houdek, M.T., Behfar, A., Sierra, R.J., Mesenchymal stem cell therapy for osteoarthritis: current perspectives. Stem Cells Cloning 8 (2015), 117–124.
60. Xu, M., Bradley, E.W., Weivoda, M.M., Hwang, S.M., Pirtskhalava, T., Decklever, T., Curran, G.L., Ogrodnik, M., Jurk, D., Johnson, K.O., Lowe, V., Tchkonia, T., Westendorf, J.J., Kirkland, J.L., Transplanted senescent cells induce an osteoarthritis-Like condition in mice. J. Gerontol. A. Biol. Sci. Med. Sci., 2016 pii: glw154. [Epub ahead of print].
61. Yan, S., Wang, M., Zhao, J., Zhang, H., Zhou, C., Jin, L., Zhang, Y., Qiu, X., Ma, B., Fan, Q., MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis. Int. J. Mol. Med. 38 (2016), 201–209.
62. Yang, S., Kim, J., Ryu, J.H., Oh, H., Chun, C.H., Kim, B.J., Min, B.H., Chun, J.S., Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction. Nat. Med. 16 (2010), 687–693.
63. Zhu, Y., Armstrong, J.L., Tchkonia, T., Kirkland, J.L., Cellular senescence and the senescent secretory phenotype in age-related chronic diseases. Curr. Opin. Clin. Nutr. Metab. Care 17 (2014), 324–328.
64. de Rezende, M.U., de Campos, G.C., Pailo, A.F., Current concepts in osteoarthritis. Acta Ortop Bras. 21 (2013), 120–122.