메뉴 건너뛰기




Volumn 3, Issue , 2013, Pages

Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; IHH PROTEIN, MOUSE; SIRT6 PROTEIN, MOUSE; SIRTUIN; SONIC HEDGEHOG PROTEIN;

EID: 84889609373     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep03022     Document Type: Article
Times cited : (41)

References (46)
  • 1
    • 3943054839 scopus 로고    scopus 로고
    • The Sir2 family of protein deacetylases
    • DOI 10.1146/annurev.biochem.73.011303.073651
    • Blander, G. & Guarente, L. The Sir2 family of protein deacetylases. Annual Review of Biochemistry 73, 417-435 (2004). (Pubitemid 39050375)
    • (2004) Annual Review of Biochemistry , vol.73 , pp. 417-435
    • Blander, G.1    Guarente, L.2
  • 2
    • 77952547233 scopus 로고    scopus 로고
    • Ten years of NAD-dependent SIR2 family deacetylases: Implications for metabolic diseases
    • Imai, S. & Guarente, L. Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases. Trends Pharmacol Sci 31, 212-220 (2010).
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 212-220
    • Imai, S.1    Guarente, L.2
  • 3
    • 0034677535 scopus 로고    scopus 로고
    • Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
    • DOI 10.1038/35001622
    • Imai, S., Armstrong, C. M., Kaeberlein, M. & Guarente, L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403, 795-800 (2000). (Pubitemid 30111843)
    • (2000) Nature , vol.403 , Issue.6771 , pp. 795-800
    • Imai, S.-I.1    Armstrong, C.M.2    Kaeberlein, M.3    Guarente, L.4
  • 6
    • 69249221533 scopus 로고    scopus 로고
    • Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
    • Michishita, E. et al. Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6. Cell Cycle 8, 2664-2666 (2009).
    • (2009) Cell Cycle , vol.8 , pp. 2664-2666
    • Michishita, E.1
  • 7
    • 77956550868 scopus 로고    scopus 로고
    • Human SIRT6 promotes DNA end resection through CtIP deacetylation
    • Kaidi, A.,Weinert, B., Choudhary, C. &Jackson, S.Human SIRT6 promotes DNA end resection through CtIP deacetylation. Science 329, 1348-1353 (2010).
    • (2010) Science , vol.329 , pp. 1348-1353
    • Kaidi, A.1    Weinert, B.2    Choudhary, C.3    Jackson, S.4
  • 8
    • 58149090925 scopus 로고    scopus 로고
    • SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaBdependent gene expression and organismal life span
    • Kawahara, T. et al. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaBdependent gene expression and organismal life span. Cell 136, 62-74 (2009).
    • (2009) Cell , vol.136 , pp. 62-74
    • Kawahara, T.1
  • 9
    • 74549142287 scopus 로고    scopus 로고
    • The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha
    • Zhong, L. et al. The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell 140, 280-293 (2010).
    • (2010) Cell , vol.140 , pp. 280-293
    • Zhong, L.1
  • 10
    • 78650724968 scopus 로고    scopus 로고
    • Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity
    • Schwer, B. et al. Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity. Proc Natl Acad Sci USA 107, 21790-21794 (2010).
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 21790-21794
    • Schwer, B.1
  • 11
    • 0024399588 scopus 로고
    • Physiological mechanisms adopted by chondrocytes in regulating longitudinal bone growth in rats
    • Hunziker, E. B. & Schenk, R. K. Physiological mechanisms adopted by chondrocytes in regulating longitudinal bone growth in rats. J Physiol 414, 55-71 (1989). (Pubitemid 19177291)
    • (1989) Journal of Physiology , vol.414 , pp. 55-71
    • Hunziker, E.B.1    Schenk, R.K.2
  • 12
    • 0038687536 scopus 로고    scopus 로고
    • Developmental regulation of the growth plate
    • DOI 10.1038/nature01657
    • Kronenberg, H. M. Developmental regulation of the growth plate. Nature 423, 332-336 (2003). (Pubitemid 40852707)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 332-336
    • Kronenberg, H.M.1
  • 13
    • 84989432345 scopus 로고
    • Cell kinetics of growth cartilage in the rat tibia. II. Measurements during ageing
    • Walker, K. V. & Kember, N. F. Cell kinetics of growth cartilage in the rat tibia. II. Measurements during ageing. Cell Tissue Kinet 5, 409-419 (1972).
    • (1972) Cell Tissue Kinet , vol.5 , pp. 409-419
    • Walker, K.V.1    Kember, N.F.2
  • 14
    • 0032908103 scopus 로고    scopus 로고
    • Transplantation of epiphyseal plate allografts between animals of different ages
    • DOI 10.1097/00004694-199905000-00022
    • Stevens, D. G., Boyer, M. I. & Bowen, C. V. Transplantation of epiphyseal plate allografts between animals of different ages. J Pediatr Orthop 19, 398-403 (1999). (Pubitemid 29214989)
    • (1999) Journal of Pediatric Orthopaedics , vol.19 , Issue.3 , pp. 398-403
    • Stevens, D.G.1    Boyer, M.I.2    Bowen, C.V.A.3
  • 15
    • 0037099054 scopus 로고    scopus 로고
    • Ihh enhances differentiation of CFK-2 chondrocytic cells and antagonizes PTHrPmediated activation of PKA
    • Deckelbaum, R. A., Chan, G., Miao, D., Goltzman, D. & Karaplis, A. C. Ihh enhances differentiation of CFK-2 chondrocytic cells and antagonizes PTHrPmediated activation of PKA. J Cell Sci 115, 3015-3025 (2002).
    • (2002) J Cell Sci , vol.115 , pp. 3015-3025
    • Deckelbaum, R.A.1    Chan, G.2    Miao, D.3    Goltzman, D.4    Karaplis, A.C.5
  • 16
    • 0029750190 scopus 로고    scopus 로고
    • Regulation of rate of cartilage differentiation by Indian Hedgehog and PTH-related protein
    • Vortkamp, A. et al. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science 273, 613-622 (1996). (Pubitemid 26262108)
    • (1996) Science , vol.273 , Issue.5275 , pp. 613-622
    • Vortkamp, A.1    Lee, K.2    Lanske, B.3    Segre, G.V.4    Kronenberg, H.M.5    Tabin, C.J.6
  • 17
    • 0031051385 scopus 로고    scopus 로고
    • The world according to hedgehog
    • DOI 10.1016/S0168-9525(96)10051-2, PII S0168952596100512
    • Hammerschmidt, M., Brook, A. & McMahon, A. P. The world according to hedgehog. Trends Genet 13, 14-21 (1997). (Pubitemid 27062504)
    • (1997) Trends in Genetics , vol.13 , Issue.1 , pp. 14-21
    • Hammerschmidt, M.1    Brook, A.2    McMahon, A.P.3
  • 18
    • 46749111932 scopus 로고    scopus 로고
    • Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy
    • DOI 10.1242/dev.018044
    • Mak, K. K., Kronenberg, H. M., Chuang, P. T., Mackem, S. & Yang, Y. Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy. Development 135, 1947-1956 (2008). (Pubitemid 351943359)
    • (2008) Development , vol.135 , Issue.11 , pp. 1947-1956
    • Mak, K.K.1    Kronenberg, H.M.2    Chuang, P.-T.3    Mackem, S.4    Yang, Y.5
  • 20
    • 0033567213 scopus 로고    scopus 로고
    • Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
    • St-Jacques, B.,Hammerschmidt, M.&McMahon, A. P. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev 13, 2072-2086 (1999). (Pubitemid 29407348)
    • (1999) Genes and Development , vol.13 , Issue.16 , pp. 2072-2086
    • St-Jacques, B.1    Hammerschmidt, M.2    McMahon, A.P.3
  • 22
    • 33748148734 scopus 로고    scopus 로고
    • Wnt9a signaling is required for joint integrity and regulation og lhh during chondrogenesis
    • DOI 10.1242/dev.02471
    • Spater, D. et al. Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. Development 133, 3039-3049 (2006). (Pubitemid 44314280)
    • (2006) Development , vol.133 , Issue.15 , pp. 3039-3049
    • Spater, D.1    Hill, T.P.2    O'Sullivan, R.J.3    Gruber, M.4    Conner, D.A.5    Hartmann, C.6
  • 23
    • 74049159081 scopus 로고    scopus 로고
    • Delta-EF1 is a negative regulator of Ihh in the developing growth plate
    • Bellon, E., Luyten, F. P. & Tylzanowski, P. delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol 187, 685-699 (2009).
    • (2009) J Cell Biol , vol.187 , pp. 685-699
    • Bellon, E.1    Luyten, F.P.2    Tylzanowski, P.3
  • 24
    • 71449099881 scopus 로고    scopus 로고
    • Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription
    • Wang, W. et al. Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development 136, 4143-4153 (2009).
    • (2009) Development , vol.136 , pp. 4143-4153
    • Wang, W.1
  • 25
    • 0034678050 scopus 로고    scopus 로고
    • Homocysteine accelerates endothelial cell senescence
    • DOI 10.1016/S0014-5793(00)01278-3, PII S0014579300012783
    • Xu, D., Neville, R. & Finkel, T. Homocysteine accelerates endothelial cell senescence. FEBS Lett 470, 20-24 (2000). (Pubitemid 30155616)
    • (2000) FEBS Letters , vol.470 , Issue.1 , pp. 20-24
    • Xu, D.1    Neville, R.2    Finkel, T.3
  • 26
    • 84874603171 scopus 로고    scopus 로고
    • Cellular senescence and the senescent secretory phenotype: Therapeutic opportunities
    • Tchkonia, T., Zhu, Y., van Deursen, J., Campisi, J. & Kirkland, J. L. Cellular senescence and the senescent secretory phenotype: therapeutic opportunities. J Clin Invest 123, 966-972 (2013).
    • (2013) J Clin Invest , vol.123 , pp. 966-972
    • Tchkonia, T.1    Zhu, Y.2    Van Deursen, J.3    Campisi, J.4    Kirkland, J.L.5
  • 28
    • 0032751087 scopus 로고    scopus 로고
    • Igf1 promotes longitudinal bone growth by insulin-like actions augmenting chondrocyte hypertrophy
    • Wang, J., Zhou, J.&Bondy, C. Igf1 promotes longitudinal bone growth by insulinlike actions augmenting chondrocyte hypertrophy. FASEB J 13, 1985-1990 (1999). (Pubitemid 29517628)
    • (1999) FASEB Journal , vol.13 , Issue.14 , pp. 1985-1990
    • Wang, J.1    Zhou, J.2    Bondy, C.A.3
  • 30
    • 79959493997 scopus 로고    scopus 로고
    • IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway
    • Wang, Y. et al. IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway. J Bone Miner Res 26, 1437-1446 (2011).
    • (2011) J Bone Miner Res , vol.26 , pp. 1437-1446
    • Wang, Y.1
  • 31
    • 84055177068 scopus 로고    scopus 로고
    • Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells
    • Oliveira, F. S. et al. Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells. J Cell Biochem 113, 204-208 (2012).
    • (2012) J Cell Biochem , vol.113 , pp. 204-208
    • Oliveira, F.S.1
  • 33
    • 66049150672 scopus 로고    scopus 로고
    • SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
    • McCord, R. A. et al. SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging (Albany NY) 1, 109-121 (2009).
    • (2009) Aging (Albany NY) , vol.1 , pp. 109-121
    • McCord, R.A.1
  • 34
    • 22944485644 scopus 로고    scopus 로고
    • Shh controls epithelial proliferation via independent pathways that converge on N-Myc
    • DOI 10.1016/j.devcel.2005.05.009, PII S1534580705001796
    • Mill, P. et al. Shh controls epithelial proliferation via independent pathways that converge on N-Myc. Dev Cell 9, 293-303 (2005). (Pubitemid 41051747)
    • (2005) Developmental Cell , vol.9 , Issue.2 , pp. 293-303
    • Mill, P.1    Mo, R.2    Hu, M.C.3    Dagnino, L.4    Rosenblum, N.D.5    Hui, C.-C.6
  • 35
    • 29744468220 scopus 로고    scopus 로고
    • Conditional deletion of Indian hedgehog from collagen type 2α1-expressing cells results in abnormal endochondral bone formation
    • DOI 10.1002/path.1870
    • Razzaque, M. S., Soegiarto, D. W., Chang, D., Long, F. & Lanske, B. Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation. J Pathol 207, 453-461 (2005). (Pubitemid 43025694)
    • (2005) Journal of Pathology , vol.207 , Issue.4 , pp. 453-461
    • Razzaque, M.S.1    Soegiarto, D.W.2    Chang, D.3    Long, F.4    Lanske, B.5
  • 36
    • 33645211374 scopus 로고    scopus 로고
    • Purmorphamine activates the Hedgehog pathway by targeting Smoothened
    • Sinha, S. & Chen, J. K. Purmorphamine activates the Hedgehog pathway by targeting Smoothened. Nat Chem Biol 2, 29-30 (2006).
    • (2006) Nat Chem Biol , vol.2 , pp. 29-30
    • Sinha, S.1    Chen, J.K.2
  • 37
    • 84868206080 scopus 로고    scopus 로고
    • Salubrinal promotes healing of surgical wounds in rat femurs
    • Zhang, P., Hamamura, K., Jiang, C., Zhao, L. & Yokota, H. Salubrinal promotes healing of surgical wounds in rat femurs. J Bone Miner Metab 30, 568-579 (2012).
    • (2012) J Bone Miner Metab , vol.30 , pp. 568-579
    • Zhang, P.1    Hamamura, K.2    Jiang, C.3    Zhao, L.4    Yokota, H.5
  • 38
    • 0025947255 scopus 로고
    • Basic cell metabolism of articular cartilage. Manometric studies
    • Otte, P. Basic cell metabolism of articular cartilage. Manometric studies. Z Rheumatol 50, 304-312 (1991).
    • (1991) Z Rheumatol , vol.50 , pp. 304-312
    • Otte, P.1
  • 39
    • 0031033421 scopus 로고    scopus 로고
    • Evidence for a negative Pasteur effect in articular cartilage
    • Lee, R. B.&Urban, J. P. Evidence for a negative Pasteur effect in articular cartilage. Biochem J 321 (Pt 1), 95-102 (1997). (Pubitemid 27032574)
    • (1997) Biochemical Journal , vol.321 , Issue.1 , pp. 95-102
    • Lee, R.B.1    Urban, J.P.G.2
  • 40
    • 84874244599 scopus 로고    scopus 로고
    • SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence
    • Cardus, A., Uryga, A. K.,Walters, G. & Erusalimsky, J. D. SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence. Cardiovasc Res 97, 571-579 (2013).
    • (2013) Cardiovasc Res , vol.97 , pp. 571-579
    • Cardus, A.1    Uryga, A.K.2    Walters, G.3    Erusalimsky, J.D.4
  • 41
    • 84880068090 scopus 로고    scopus 로고
    • The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells
    • Sharma, A. et al. The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. J Biol Chem 288, 18439-18447 (2013).
    • (2013) J Biol Chem , vol.288 , pp. 18439-18447
    • Sharma, A.1
  • 42
    • 84863974838 scopus 로고    scopus 로고
    • Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence
    • Mao, Z. et al. Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence. Proc Natl Acad Sci USA 109, 11800-11805 (2012).
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 11800-11805
    • Mao, Z.1
  • 43
    • 0023130144 scopus 로고
    • Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth
    • Hunziker, E. B., Schenk, R. K. & Cruz-Orive, L. M. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. J Bone Joint Surg Am 69, 162-173 (1987). (Pubitemid 17026012)
    • (1987) Journal of Bone and Joint Surgery - Series A , vol.69 , Issue.2 , pp. 162-173
    • Hunziker, E.B.1    Schenk, R.K.2    Cruz-Orive, L.-M.3
  • 44
    • 0029875398 scopus 로고    scopus 로고
    • Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: Differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor
    • DOI 10.1083/jcb.133.2.457
    • Shukunami, C. et al. Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor. The Journal of Cell Biology 133, 457-468 (1996). (Pubitemid 26131617)
    • (1996) Journal of Cell Biology , vol.133 , Issue.2 , pp. 457-468
    • Shukunami, C.1    Shigeno, C.2    Atsumi, T.3    Ishizeki, K.4    Suzuki, F.5    Hiraki, Y.6
  • 45
    • 50349096522 scopus 로고    scopus 로고
    • Primary culture and phenotyping of murine chondrocytes
    • Gosset, M., Berenbaum, F., Thirion, S. & Jacques, C. Primary culture and phenotyping of murine chondrocytes. Nat. Protocols 3, 1253-1260 (2008).
    • (2008) Nat. Protocols , vol.3 , pp. 1253-1260
    • Gosset, M.1    Berenbaum, F.2    Thirion, S.3    Jacques, C.4
  • 46
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W.,A new mathematical model for relative quantification in real-time RT-PCR, Nucleic Acids Res, 2001, 29,e45
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.