MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis

International Journal of Molecular Medicine

Volumn 38, Issue 1, 2016, Pages 201-209

  Yan, Shiju ^a   Wang, Meng ^a   Zhao, Jian ^a   Zhang, Hongtao ^a   Zhou, Chengpei ^a   Jin, Lei ^a   Zhang, Yinglong ^a   Qiu, Xiuchun ^a   Ma, Baoan ^a   Fan, Qingyu ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Chondrocyte; Lentivirus; MicroRNA 34a; Osteoarthritis; P53; Silent information regulator 1

Indexed keywords

MICRORNA 34A; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SIRTUIN 1; MICRORNA; MIRN34 MICRORNA, HUMAN; OLIGONUCLEOTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; HUMAN; HUMAN CELL; KNEE MENISCUS; LUCIFERASE ASSAY; MALE; NONHUMAN; OSTEOARTHRITIS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN RNA BINDING; RAT; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CARTILAGE; CASE CONTROL STUDY; CHONDROCYTE; GENETIC TRANSFECTION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; REPRODUCIBILITY; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; CARTILAGE; CASE-CONTROL STUDIES; CELL PROLIFERATION; CHONDROCYTES; DISEASE PROGRESSION; HUMANS; MALE; MICRORNAS; MIDDLE AGED; OLIGONUCLEOTIDES; OSTEOARTHRITIS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; SIRTUIN 1; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84978808473     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2016.2618     Document Type: Article

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