Overexpression of Sirtuin 6 suppresses cellular senescence and NF-κB mediated inflammatory responses in osteoarthritis development

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Wu, Yaosen ^a   Chen, Linwei ^b   Wang, Ye ^b   Li, Wanli ^b   Lin, Yan ^a   Yu, Dongsheng ^c   Zhang, Liang ^d   Li, Fangcai ^b   Pan, Zhijun ^b  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d YANGZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 2; COLLAGENASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; SIRT6 PROTEIN, HUMAN; SIRT6 PROTEIN, MOUSE; SIRTUIN; TRANSCRIPTION FACTOR RELA;

AGING; ANIMAL; ARTICULAR CARTILAGE; C57BL MOUSE; CELL AGING; CELL NUCLEUS; CHONDROCYTE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INFLAMMATION; KNEE OSTEOARTHRITIS; METABOLISM; PATHOLOGY; PROTEIN TRANSPORT;

AGING; ANIMALS; CARTILAGE, ARTICULAR; CELL AGING; CELL NUCLEUS; CHONDROCYTES; COLLAGEN TYPE II; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 13; MICE, INBRED C57BL; NF-KAPPA B; OSTEOARTHRITIS, KNEE; PROTEIN TRANSPORT; SIRTUINS; TRANSCRIPTION FACTOR RELA;

EID: 84949498541     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep17602     Document Type: Article

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