-
1
-
-
84898967209
-
A phase I/II, multiple-dose, dose-escalation study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with advanced solid tumors
-
Angevin, E., Tabernero, J., Elez, E., Cohen, S.J., Bahleda, R., van Laethem, J.L.,.. Kurzrock, R., A phase I/II, multiple-dose, dose-escalation study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with advanced solid tumors. Clinical Cancer Research 20 (2014), 2192–2204.
-
(2014)
Clinical Cancer Research
, vol.20
, pp. 2192-2204
-
-
Angevin, E.1
Tabernero, J.2
Elez, E.3
Cohen, S.J.4
Bahleda, R.5
van Laethem, J.L.6
Kurzrock, R.7
-
2
-
-
4444319419
-
The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis
-
Bates, R.C., DeLeo, M.J. III, Mercurio, A.M., The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis. Experimental Cell Research 299 (2004), 315–324.
-
(2004)
Experimental Cell Research
, vol.299
, pp. 315-324
-
-
Bates, R.C.1
DeLeo, M.J.2
Mercurio, A.M.3
-
3
-
-
5644252874
-
TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling
-
Becker, C., Fantini, M.C., Schramm, C., Lehr, H.A., Wirtz, S., Nikolaev, A.,.. Neurath, M.F., TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling. Immunity 21 (2004), 491–501.
-
(2004)
Immunity
, vol.21
, pp. 491-501
-
-
Becker, C.1
Fantini, M.C.2
Schramm, C.3
Lehr, H.A.4
Wirtz, S.5
Nikolaev, A.6
Neurath, M.F.7
-
4
-
-
8444230395
-
Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival
-
Benoy, I.H., Salgado, R., Van Dam, P., Geboers, K., Van Marck, E., Scharpé, S.,.. Dirix, L.Y., Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival. Clinical Cancer Research 10 (2004), 7157–7162.
-
(2004)
Clinical Cancer Research
, vol.10
, pp. 7157-7162
-
-
Benoy, I.H.1
Salgado, R.2
Van Dam, P.3
Geboers, K.4
Van Marck, E.5
Scharpé, S.6
Dirix, L.Y.7
-
5
-
-
84874607100
-
TGF-beta inhibition enhances chemotherapy action against triple-negative breast cancer
-
Bhola, N.E., Balko, J.M., Dugger, T.C., Kuba, M.G., Sanchez, V., Sanders, M.,.. Arteaga, C.L., TGF-beta inhibition enhances chemotherapy action against triple-negative breast cancer. The Journal of Clinical Investigation 123 (2013), 1348–1358.
-
(2013)
The Journal of Clinical Investigation
, vol.123
, pp. 1348-1358
-
-
Bhola, N.E.1
Balko, J.M.2
Dugger, T.C.3
Kuba, M.G.4
Sanchez, V.5
Sanders, M.6
Arteaga, C.L.7
-
6
-
-
85047698213
-
Correlation of snail expression with histological grade and lymph node status in breast carcinomas
-
Blanco, M.J., Moreno-Bueno, G., Sarrio, D., Locascio, A., Cano, A., Palacios, J., Nieto, M.A., Correlation of snail expression with histological grade and lymph node status in breast carcinomas. Oncogene 21 (2002), 3241–3246.
-
(2002)
Oncogene
, vol.21
, pp. 3241-3246
-
-
Blanco, M.J.1
Moreno-Bueno, G.2
Sarrio, D.3
Locascio, A.4
Cano, A.5
Palacios, J.6
Nieto, M.A.7
-
7
-
-
79959989874
-
Salinomycin induces calpain and cytochrome c-mediated neuronal cell death
-
Boehmerle, W., Endres, M., Salinomycin induces calpain and cytochrome c-mediated neuronal cell death. Cell Death & Disease, 2, 2011, e168.
-
(2011)
Cell Death & Disease
, vol.2
-
-
Boehmerle, W.1
Endres, M.2
-
8
-
-
84906789840
-
Specific targeting of neurotoxic side effects and pharmacological profile of the novel cancer stem cell drug salinomycin in mice
-
Boehmerle, W., Muenzfeld, H., Springer, A., Huehnchen, P., Endres, M., Specific targeting of neurotoxic side effects and pharmacological profile of the novel cancer stem cell drug salinomycin in mice. Journal of Molecular Medicine 92 (2014), 889–900.
-
(2014)
Journal of Molecular Medicine
, vol.92
, pp. 889-900
-
-
Boehmerle, W.1
Muenzfeld, H.2
Springer, A.3
Huehnchen, P.4
Endres, M.5
-
9
-
-
0037326569
-
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors
-
Bolos, V., Peinado, H., Perez-Moreno, M.A., Fraga, M.F., Esteller, M., Cano, A., The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. Journal of Cell Science 116 (2003), 499–511.
-
(2003)
Journal of Cell Science
, vol.116
, pp. 499-511
-
-
Bolos, V.1
Peinado, H.2
Perez-Moreno, M.A.3
Fraga, M.F.4
Esteller, M.5
Cano, A.6
-
10
-
-
84944937210
-
Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
-
Borghaei, H., Paz-Ares, L., Horn, L., Spigel, D.R., Steins, M., Ready, N.E.,.. Brahmer, J.R., Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. The New England Journal of Medicine 373 (2015), 1627–1639.
-
(2015)
The New England Journal of Medicine
, vol.373
, pp. 1627-1639
-
-
Borghaei, H.1
Paz-Ares, L.2
Horn, L.3
Spigel, D.R.4
Steins, M.5
Ready, N.E.6
Brahmer, J.R.7
-
11
-
-
84861527239
-
To differentiate or not–routes towards metastasis
-
Brabletz, T., To differentiate or not–routes towards metastasis. Nature Reviews. Cancer 12 (2012), 425–436.
-
(2012)
Nature Reviews. Cancer
, vol.12
, pp. 425-436
-
-
Brabletz, T.1
-
12
-
-
22144497081
-
Invasion and metastasis in colorectal cancer: epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and beta-catenin
-
Brabletz, T., Hlubek, F., Spaderna, S., Schmalhofer, O., Hiendlmeyer, E., Jung, A., Kirchner, T., Invasion and metastasis in colorectal cancer: epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and beta-catenin. Cells, Tissues, Organs 179 (2005), 56–65.
-
(2005)
Cells, Tissues, Organs
, vol.179
, pp. 56-65
-
-
Brabletz, T.1
Hlubek, F.2
Spaderna, S.3
Schmalhofer, O.4
Hiendlmeyer, E.5
Jung, A.6
Kirchner, T.7
-
13
-
-
0035964349
-
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
-
Brabletz, T., Jung, A., Reu, S., Porzner, M., Hlubek, F., Kunz-Schughart, L.A.,.. Kirchner, T., Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proceedings of the National Academy of Sciences of the United States of America 98 (2001), 10356–10361.
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, pp. 10356-10361
-
-
Brabletz, T.1
Jung, A.2
Reu, S.3
Porzner, M.4
Hlubek, F.5
Kunz-Schughart, L.A.6
Kirchner, T.7
-
14
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer, J.R., Tykodi, S.S., Chow, L.Q., Hwu, W.J., Topalian, S.L., Hwu, P.,.. Wigginton, J.M., Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. The New England Journal of Medicine 366 (2012), 2455–2465.
-
(2012)
The New England Journal of Medicine
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
Wigginton, J.M.7
-
15
-
-
84952939889
-
Targeting CXCR1 on breast cancer stem cells: Signaling pathways and clinical application modelling
-
Brandolini, L., Cristiano, L., Fidoamore, A., De Pizzol, M., Di Giacomo, E., Florio, T.M.,.. Cimini, A., Targeting CXCR1 on breast cancer stem cells: Signaling pathways and clinical application modelling. Oncotarget 6 (2015), 43375–43394.
-
(2015)
Oncotarget
, vol.6
, pp. 43375-43394
-
-
Brandolini, L.1
Cristiano, L.2
Fidoamore, A.3
De Pizzol, M.4
Di Giacomo, E.5
Florio, T.M.6
Cimini, A.7
-
16
-
-
84871998076
-
An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance
-
Byers, L.A., Diao, L., Wang, J., Saintigny, P., Girard, L., Peyton, M.,.. Heymach, J.V., An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clinical Cancer Research 19 (2013), 279–290.
-
(2013)
Clinical Cancer Research
, vol.19
, pp. 279-290
-
-
Byers, L.A.1
Diao, L.2
Wang, J.3
Saintigny, P.4
Girard, L.5
Peyton, M.6
Heymach, J.V.7
-
17
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano, A., Perez-Moreno, M.A., Rodrigo, I., Locascio, A., Blanco, M.J., del Barrio, M.G.,.. Nieto, M.A., The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nature Cell Biology 2 (2000), 76–83.
-
(2000)
Nature Cell Biology
, vol.2
, pp. 76-83
-
-
Cano, A.1
Perez-Moreno, M.A.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.J.5
del Barrio, M.G.6
Nieto, M.A.7
-
18
-
-
84866371806
-
Phenotypic high-throughput screening elucidates target pathway in breast cancer stem cell-like cells
-
Carmody, L.C., Germain, A.R., VerPlank, L., Nag, P.P., Munoz, B., Perez, J.R., Palmer, M.A., Phenotypic high-throughput screening elucidates target pathway in breast cancer stem cell-like cells. Journal of Biomolecular Screening 17 (2012), 1204–1210.
-
(2012)
Journal of Biomolecular Screening
, vol.17
, pp. 1204-1210
-
-
Carmody, L.C.1
Germain, A.R.2
VerPlank, L.3
Nag, P.P.4
Munoz, B.5
Perez, J.R.6
Palmer, M.A.7
-
19
-
-
19944429545
-
Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2
-
Casilli, F., Bianchini, A., Gloaguen, I., Biordi, L., Alesse, E., Festuccia, C.,.. Bertini, R., Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2. Biochemical Pharmacology 69 (2005), 385–394.
-
(2005)
Biochemical Pharmacology
, vol.69
, pp. 385-394
-
-
Casilli, F.1
Bianchini, A.2
Gloaguen, I.3
Biordi, L.4
Alesse, E.5
Festuccia, C.6
Bertini, R.7
-
20
-
-
33845809125
-
Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2
-
Chaffer, C.L., Brennan, J.P., Slavin, J.L., Blick, T., Thompson, E.W., Williams, E.D., Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2. Cancer Research 66 (2006), 11271–11278.
-
(2006)
Cancer Research
, vol.66
, pp. 11271-11278
-
-
Chaffer, C.L.1
Brennan, J.P.2
Slavin, J.L.3
Blick, T.4
Thompson, E.W.5
Williams, E.D.6
-
21
-
-
84923251407
-
Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
-
Chen, L., Gibbons, D.L., Goswami, S., Cortez, M.A., Ahn, Y.H., Byers, L.A.,.. Qin, F.X., Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression. Nature Communications, 5, 2014, 5241.
-
(2014)
Nature Communications
, vol.5
, pp. 5241
-
-
Chen, L.1
Gibbons, D.L.2
Goswami, S.3
Cortez, M.A.4
Ahn, Y.H.5
Byers, L.A.6
Qin, F.X.7
-
22
-
-
84863247475
-
A cell-based small molecule screening method for identifying inhibitors of epithelial-mesenchymal transition in carcinoma
-
Chua, K.N., Sim, W.J., Racine, V., Lee, S.Y., Goh, B.C., Thiery, J.P., A cell-based small molecule screening method for identifying inhibitors of epithelial-mesenchymal transition in carcinoma. PLoS One, 7, 2012, e33183.
-
(2012)
PLoS One
, vol.7
-
-
Chua, K.N.1
Sim, W.J.2
Racine, V.3
Lee, S.Y.4
Goh, B.C.5
Thiery, J.P.6
-
23
-
-
69549131213
-
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
-
Creighton, C.J., Li, X., Landis, M., Dixon, J.M., Neumeister, V.M., Sjolund, A.,.. Chang, J.C., Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proceedings of the National Academy of Sciences of the United States of America 106 (2009), 13820–13825.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 13820-13825
-
-
Creighton, C.J.1
Li, X.2
Landis, M.3
Dixon, J.M.4
Neumeister, V.M.5
Sjolund, A.6
Chang, J.C.7
-
24
-
-
85016851454
-
The IL-8/IL-8R axis: a double agent in tumor immune resistance
-
(pii: E22)
-
David, J.M., Dominguez, C., Hamilton, D.H., Palena, C., The IL-8/IL-8R axis: a double agent in tumor immune resistance. Vaccines (Basel), 4, 2016 (pii: E22).
-
(2016)
Vaccines (Basel)
, vol.4
-
-
David, J.M.1
Dominguez, C.2
Hamilton, D.H.3
Palena, C.4
-
25
-
-
84921279897
-
Gramicidin A blocks tumor growth and angiogenesis through inhibition of hypoxia-inducible factor in renal cell carcinoma
-
David, J.M., Owens, T.A., Inge, L.J., Bremner, R.M., Rajasekaran, A.K., Gramicidin A blocks tumor growth and angiogenesis through inhibition of hypoxia-inducible factor in renal cell carcinoma. Molecular Cancer Therapeutics 13 (2014), 788–799.
-
(2014)
Molecular Cancer Therapeutics
, vol.13
, pp. 788-799
-
-
David, J.M.1
Owens, T.A.2
Inge, L.J.3
Bremner, R.M.4
Rajasekaran, A.K.5
-
26
-
-
34548329486
-
Differentiation plasticity regulated by TGF-beta family proteins in development and disease
-
Derynck, R., Akhurst, R.J., Differentiation plasticity regulated by TGF-beta family proteins in development and disease. Nature Cell Biology 9 (2007), 1000–1004.
-
(2007)
Nature Cell Biology
, vol.9
, pp. 1000-1004
-
-
Derynck, R.1
Akhurst, R.J.2
-
27
-
-
84943791915
-
A phase I trial combining carboplatin/doxorubicin with tocilizumab, an anti-IL-6R monoclonal antibody, and interferon-alpha2b in patients with recurrent epithelial ovarian cancer
-
Dijkgraaf, E.M., Santegoets, S.J., Reyners, A.K., Goedemans, R., Wouters, M.C., Kenter, G.G.,.. Kroep, J.R., A phase I trial combining carboplatin/doxorubicin with tocilizumab, an anti-IL-6R monoclonal antibody, and interferon-alpha2b in patients with recurrent epithelial ovarian cancer. Annals of Oncology 26 (2015), 2141–2149.
-
(2015)
Annals of Oncology
, vol.26
, pp. 2141-2149
-
-
Dijkgraaf, E.M.1
Santegoets, S.J.2
Reyners, A.K.3
Goedemans, R.4
Wouters, M.C.5
Kenter, G.G.6
Kroep, J.R.7
-
28
-
-
84924175796
-
Overexpression of brachyury contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
-
Du, R., Wu, S., Lv, X., Fang, H., Wu, S., Kang, J., Overexpression of brachyury contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research, 33, 2014, 105.
-
(2014)
Journal of Experimental & Clinical Cancer Research
, vol.33
, pp. 105
-
-
Du, R.1
Wu, S.2
Lv, X.3
Fang, H.4
Wu, S.5
Kang, J.6
-
29
-
-
20144388095
-
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
-
Eger, A., Aigner, K., Sonderegger, S., Dampier, B., Oehler, S., Schreiber, M.,.. Foisner, R., DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene 24 (2005), 2375–2385.
-
(2005)
Oncogene
, vol.24
, pp. 2375-2385
-
-
Eger, A.1
Aigner, K.2
Sonderegger, S.3
Dampier, B.4
Oehler, S.5
Schreiber, M.6
Foisner, R.7
-
30
-
-
16844368863
-
Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
-
Elloul, S., Elstrand, M.B., Nesland, J.M., Trope, C.G., Kvalheim, G., Goldberg, I.,.. Davidson, B., Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma. Cancer 103 (2005), 1631–1643.
-
(2005)
Cancer
, vol.103
, pp. 1631-1643
-
-
Elloul, S.1
Elstrand, M.B.2
Nesland, J.M.3
Trope, C.G.4
Kvalheim, G.5
Goldberg, I.6
Davidson, B.7
-
31
-
-
67749122122
-
Targeting PI3K signalling in cancer: Opportunities, challenges and limitations
-
Engelman, J.A., Targeting PI3K signalling in cancer: Opportunities, challenges and limitations. Nature Reviews. Cancer 9 (2009), 550–562.
-
(2009)
Nature Reviews. Cancer
, vol.9
, pp. 550-562
-
-
Engelman, J.A.1
-
32
-
-
1542373736
-
Repression of Na,K-ATPase beta1-subunit by the transcription factor snail in carcinoma
-
Espineda, C.E., Chang, J.H., Twiss, J., Rajasekaran, S.A., Rajasekaran, A.K., Repression of Na,K-ATPase beta1-subunit by the transcription factor snail in carcinoma. Molecular Biology of the Cell 15 (2004), 1364–1373.
-
(2004)
Molecular Biology of the Cell
, vol.15
, pp. 1364-1373
-
-
Espineda, C.E.1
Chang, J.H.2
Twiss, J.3
Rajasekaran, S.A.4
Rajasekaran, A.K.5
-
33
-
-
0037452992
-
IL-8-induced migratory responses through CXCR1 and CXCR2: association with phosphorylation and cellular redistribution of focal adhesion kinase
-
Feniger-Barish, R., Yron, I., Meshel, T., Matityahu, E., Ben-Baruch, A., IL-8-induced migratory responses through CXCR1 and CXCR2: association with phosphorylation and cellular redistribution of focal adhesion kinase. Biochemistry 42 (2003), 2874–2886.
-
(2003)
Biochemistry
, vol.42
, pp. 2874-2886
-
-
Feniger-Barish, R.1
Yron, I.2
Meshel, T.3
Matityahu, E.4
Ben-Baruch, A.5
-
34
-
-
79960952144
-
IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells
-
Fernando, R.I., Castillo, M.D., Litzinger, M., Hamilton, D.H., Palena, C., IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells. Cancer Research 71 (2011), 5296–5306.
-
(2011)
Cancer Research
, vol.71
, pp. 5296-5306
-
-
Fernando, R.I.1
Castillo, M.D.2
Litzinger, M.3
Hamilton, D.H.4
Palena, C.5
-
35
-
-
84993928833
-
IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib
-
Fernando, R.I., Hamilton, D.H., Dominguez, C., David, J.M., McCampbell, K.K., Palena, C., IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib. Oncotarget 71 (2016), 5296–5306.
-
(2016)
Oncotarget
, vol.71
, pp. 5296-5306
-
-
Fernando, R.I.1
Hamilton, D.H.2
Dominguez, C.3
David, J.M.4
McCampbell, K.K.5
Palena, C.6
-
36
-
-
76649138588
-
The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells
-
Fernando, R.I., Litzinger, M., Trono, P., Hamilton, D.H., Schlom, J., Palena, C., The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells. The Journal of Clinical Investigation 120 (2010), 533–544.
-
(2010)
The Journal of Clinical Investigation
, vol.120
, pp. 533-544
-
-
Fernando, R.I.1
Litzinger, M.2
Trono, P.3
Hamilton, D.H.4
Schlom, J.5
Palena, C.6
-
37
-
-
84948429460
-
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
-
Fischer, K.R., Durrans, A., Lee, S., Sheng, J., Li, F., Wong, S.T.,.. Gao, D., Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance. Nature 527 (2015), 472–476.
-
(2015)
Nature
, vol.527
, pp. 472-476
-
-
Fischer, K.R.1
Durrans, A.2
Lee, S.3
Sheng, J.4
Li, F.5
Wong, S.T.6
Gao, D.7
-
38
-
-
84918527502
-
Macrophage-secreted IL-8 induces epithelial-mesenchymal transition in hepatocellular carcinoma cells by activating the JAK2/STAT3/Snail pathway
-
Fu, X.T., Dai, Z., Song, K., Zhang, Z.J., Zhou, Z.J., Zhou, S.L.,.. Fan, J., Macrophage-secreted IL-8 induces epithelial-mesenchymal transition in hepatocellular carcinoma cells by activating the JAK2/STAT3/Snail pathway. International Journal of Oncology 46 (2015), 587–596.
-
(2015)
International Journal of Oncology
, vol.46
, pp. 587-596
-
-
Fu, X.T.1
Dai, Z.2
Song, K.3
Zhang, Z.J.4
Zhou, Z.J.5
Zhou, S.L.6
Fan, J.7
-
39
-
-
73149112786
-
A high-affinity fully human anti-IL-6 mAb, 1339, for the treatment of multiple myeloma
-
Fulciniti, M., Hideshima, T., Vermot-Desroches, C., Pozzi, S., Nanjappa, P., Shen, Z.,.. Munshi, N.C., A high-affinity fully human anti-IL-6 mAb, 1339, for the treatment of multiple myeloma. Clinical Cancer Research 15 (2009), 7144–7152.
-
(2009)
Clinical Cancer Research
, vol.15
, pp. 7144-7152
-
-
Fulciniti, M.1
Hideshima, T.2
Vermot-Desroches, C.3
Pozzi, S.4
Nanjappa, P.5
Shen, Z.6
Munshi, N.C.7
-
40
-
-
84945542492
-
The generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic
-
Gabitzsch, E.S., Tsang, K.Y., Palena, C., David, J.M., Fantini, M., Kwilas, A.,.. Schlom, J., The generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic. Oncotarget 6 (2015), 31344–31359.
-
(2015)
Oncotarget
, vol.6
, pp. 31344-31359
-
-
Gabitzsch, E.S.1
Tsang, K.Y.2
Palena, C.3
David, J.M.4
Fantini, M.5
Kwilas, A.6
Schlom, J.7
-
41
-
-
39649102143
-
Epithelial-to-mesenchymal transition is important to metastasis, but questions remain
-
Garber, K., Epithelial-to-mesenchymal transition is important to metastasis, but questions remain. Journal of the National Cancer Institute, 100(232-233), 2008, 239.
-
(2008)
Journal of the National Cancer Institute
, vol.100
, Issue.232-233
, pp. 239
-
-
Garber, K.1
-
42
-
-
84929481480
-
Pembrolizumab for the treatment of non-small-cell lung cancer
-
Garon, E.B., Rizvi, N.A., Hui, R., Leighl, N., Balmanoukian, A.S., Eder, J.P.,.. Gandhi, L., Pembrolizumab for the treatment of non-small-cell lung cancer. The New England Journal of Medicine 372 (2015), 2018–2028.
-
(2015)
The New England Journal of Medicine
, vol.372
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
Leighl, N.4
Balmanoukian, A.S.5
Eder, J.P.6
Gandhi, L.7
-
43
-
-
84874655249
-
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells
-
Germain, A.R., Carmody, L.C., Nag, P.P., Morgan, B., Verplank, L., Fernandez, C.,.. Munoz, B., Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells. Bioorganic & Medicinal Chemistry Letters 23 (2013), 1834–1838.
-
(2013)
Bioorganic & Medicinal Chemistry Letters
, vol.23
, pp. 1834-1838
-
-
Germain, A.R.1
Carmody, L.C.2
Nag, P.P.3
Morgan, B.4
Verplank, L.5
Fernandez, C.6
Munoz, B.7
-
44
-
-
76649113726
-
CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts
-
Ginestier, C., Liu, S., Diebel, M.E., Korkaya, H., Luo, M., Brown, M.,.. Wicha, M.S., CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts. The Journal of Clinical Investigation 120 (2010), 485–497.
-
(2010)
The Journal of Clinical Investigation
, vol.120
, pp. 485-497
-
-
Ginestier, C.1
Liu, S.2
Diebel, M.E.3
Korkaya, H.4
Luo, M.5
Brown, M.6
Wicha, M.S.7
-
45
-
-
37249030356
-
A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer
-
Gravdal, K., Halvorsen, O.J., Haukaas, S.A., Akslen, L.A., A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer. Clinical Cancer Research 13 (2007), 7003–7011.
-
(2007)
Clinical Cancer Research
, vol.13
, pp. 7003-7011
-
-
Gravdal, K.1
Halvorsen, O.J.2
Haukaas, S.A.3
Akslen, L.A.4
-
46
-
-
84996548609
-
Immune impact induced by PROSTVAC (PSA-TRICOM), a therapeutic vaccine for prostate cancer
-
Gulley, J.L., Madan, R.A., Tsang, K.Y., Jochems, C., Marte, J.L., Farsaci, B.,.. Schlom, J., Immune impact induced by PROSTVAC (PSA-TRICOM), a therapeutic vaccine for prostate cancer. Cancer Immunology Research 2 (2014), 133–141.
-
(2014)
Cancer Immunology Research
, vol.2
, pp. 133-141
-
-
Gulley, J.L.1
Madan, R.A.2
Tsang, K.Y.3
Jochems, C.4
Marte, J.L.5
Farsaci, B.6
Schlom, J.7
-
47
-
-
68749099671
-
Identification of selective inhibitors of cancer stem cells by high-throughput screening
-
Gupta, P.B., Onder, T.T., Jiang, G., Tao, K., Kuperwasser, C., Weinberg, R.A., Lander, E.S., Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138 (2009), 645–659.
-
(2009)
Cell
, vol.138
, pp. 645-659
-
-
Gupta, P.B.1
Onder, T.T.2
Jiang, G.3
Tao, K.4
Kuperwasser, C.5
Weinberg, R.A.6
Lander, E.S.7
-
48
-
-
84863938543
-
Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors
-
Gurney, A., Axelrod, F., Bond, C.J., Cain, J., Chartier, C., Donigan, L.,.. Hoey, T., Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors. Proceedings of the National Academy of Sciences of the United States of America 109 (2012), 11717–11722.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, pp. 11717-11722
-
-
Gurney, A.1
Axelrod, F.2
Bond, C.J.3
Cain, J.4
Chartier, C.5
Donigan, L.6
Hoey, T.7
-
49
-
-
68949204214
-
Oxygen regulates epithelial-to-mesenchymal transition: Insights into molecular mechanisms and relevance to disease
-
Haase, V.H., Oxygen regulates epithelial-to-mesenchymal transition: Insights into molecular mechanisms and relevance to disease. Kidney International 76 (2009), 492–499.
-
(2009)
Kidney International
, vol.76
, pp. 492-499
-
-
Haase, V.H.1
-
50
-
-
85007022672
-
Targeting estrogen receptor signaling with fulvestrant enhances immune and chemotherapy-mediated cytotoxicity of human lung cancer
-
Hamilton, D.H., Matthews Griner, L., Keller, J.M., Hu, X., Southall, N., Marugan, J.,.. Palena, C., Targeting estrogen receptor signaling with fulvestrant enhances immune and chemotherapy-mediated cytotoxicity of human lung cancer. Clinical Cancer Research, 2016.
-
(2016)
Clinical Cancer Research
-
-
Hamilton, D.H.1
Matthews Griner, L.2
Keller, J.M.3
Hu, X.4
Southall, N.5
Marugan, J.6
Palena, C.7
-
51
-
-
84993939994
-
Brachyury, a vaccine target, is overexpressed in triple-negative breast cancer
-
Hamilton, D.H., Roselli, M., Ferroni, P., Costarelli, L., Cavaliere, F., Taffuri, M.,.. Guadagni, F., Brachyury, a vaccine target, is overexpressed in triple-negative breast cancer. Endocrine-Related Cancer 23 (2016), 783–796.
-
(2016)
Endocrine-Related Cancer
, vol.23
, pp. 783-796
-
-
Hamilton, D.H.1
Roselli, M.2
Ferroni, P.3
Costarelli, L.4
Cavaliere, F.5
Taffuri, M.6
Guadagni, F.7
-
52
-
-
84886745437
-
Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine
-
Hamilton, D.H., Litzinger, M.T., Jales, A., Huang, B., Fernando, R.I., Hodge, J.W.,.. Palena, C., Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine. Oncotarget 4 (2013), 1777–1790.
-
(2013)
Oncotarget
, vol.4
, pp. 1777-1790
-
-
Hamilton, D.H.1
Litzinger, M.T.2
Jales, A.3
Huang, B.4
Fernando, R.I.5
Hodge, J.W.6
Palena, C.7
-
53
-
-
84892818249
-
Expression of Brachyury gene is a significant prognostic factor for primary lung carcinoma
-
Haro, A., Yano, T., Kohno, M., Yoshida, T., Koga, T., Okamoto, T.,.. Maehara, Y., Expression of Brachyury gene is a significant prognostic factor for primary lung carcinoma. Annals of Surgical Oncology 20:Suppl. 3 (2013), S509–S516.
-
(2013)
Annals of Surgical Oncology
, vol.20
, pp. S509-S516
-
-
Haro, A.1
Yano, T.2
Kohno, M.3
Yoshida, T.4
Koga, T.5
Okamoto, T.6
Maehara, Y.7
-
54
-
-
0029553183
-
An overview of epithelio-mesenchymal transformation
-
Hay, E.D., An overview of epithelio-mesenchymal transformation. Acta Anatomica (Basel) 154 (1995), 8–20.
-
(1995)
Acta Anatomica (Basel)
, vol.154
, pp. 8-20
-
-
Hay, E.D.1
-
55
-
-
20744439516
-
The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it
-
Hay, E.D., The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it. Developmental Dynamics 233 (2005), 706–720.
-
(2005)
Developmental Dynamics
, vol.233
, pp. 706-720
-
-
Hay, E.D.1
-
56
-
-
84993928847
-
Phase I, dose-escalation, clinical trial of MVA-Brachyury-TRICOM vaccine demonstrating safety and brachyury-specific T cell responses
-
Heery, C.R., Donahue, R.N., Lepone, L., Grenga, I., Richards, J., Metenou, S.,.. Schlom, J., Phase I, dose-escalation, clinical trial of MVA-Brachyury-TRICOM vaccine demonstrating safety and brachyury-specific T cell responses. Journal for ImmunoTherapy of Cancer 3 (2015), 1–2.
-
(2015)
Journal for ImmunoTherapy of Cancer
, vol.3
, pp. 1-2
-
-
Heery, C.R.1
Donahue, R.N.2
Lepone, L.3
Grenga, I.4
Richards, J.5
Metenou, S.6
Schlom, J.7
-
57
-
-
84945561165
-
Phase I trial of a yeast-based therapeutic cancer vaccine (GI-6301) targeting the transcription factor brachyury
-
Heery, C.R., Singh, B.H., Rauckhorst, M., Marte, J.L., Donahue, R.N., Grenga, I.,.. Gulley, J.L., Phase I trial of a yeast-based therapeutic cancer vaccine (GI-6301) targeting the transcription factor brachyury. Cancer Immunology Research 3 (2015), 1248–1256.
-
(2015)
Cancer Immunology Research
, vol.3
, pp. 1248-1256
-
-
Heery, C.R.1
Singh, B.H.2
Rauckhorst, M.3
Marte, J.L.4
Donahue, R.N.5
Grenga, I.6
Gulley, J.L.7
-
58
-
-
84939783826
-
Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway
-
Herbertz, S., Sawyer, J.S., Stauber, A.J., Gueorguieva, I., Driscoll, K.E., Estrem, S.T.,.. Lahn, M.M., Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway. Drug Design, Development and Therapy 9 (2015), 4479–4499.
-
(2015)
Drug Design, Development and Therapy
, vol.9
, pp. 4479-4499
-
-
Herbertz, S.1
Sawyer, J.S.2
Stauber, A.J.3
Gueorguieva, I.4
Driscoll, K.E.5
Estrem, S.T.6
Lahn, M.M.7
-
59
-
-
84892938899
-
Comprehensive analysis of beta-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/beta-catenin signaling
-
Herbst, A., Jurinovic, V., Krebs, S., Thieme, S.E., Blum, H., Goke, B., Kolligs, F.T., Comprehensive analysis of beta-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/beta-catenin signaling. BMC Genomics, 15, 2014, 74.
-
(2014)
BMC Genomics
, vol.15
, pp. 74
-
-
Herbst, A.1
Jurinovic, V.2
Krebs, S.3
Thieme, S.E.4
Blum, H.5
Goke, B.6
Kolligs, F.T.7
-
60
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst, R.S., Soria, J.C., Kowanetz, M., Fine, G.D., Hamid, O., Gordon, M.S.,.. Hodi, F.S., Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 515 (2014), 563–567.
-
(2014)
Nature
, vol.515
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
Fine, G.D.4
Hamid, O.5
Gordon, M.S.6
Hodi, F.S.7
-
61
-
-
0022499547
-
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin
-
Hirano, T., Yasukawa, K., Harada, H., Taga, T., Watanabe, Y., Matsuda, T., Kashiwamura, S., Nakajima, K., Koyama, K., Iwamatsu, A., et al. Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature 324 (1986), 73–76.
-
(1986)
Nature
, vol.324
, pp. 73-76
-
-
Hirano, T.1
Yasukawa, K.2
Harada, H.3
Taga, T.4
Watanabe, Y.5
Matsuda, T.6
Kashiwamura, S.7
Nakajima, K.8
Koyama, K.9
Iwamatsu, A.10
-
62
-
-
28844494352
-
Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation
-
Hiscox, S., Jiang, W.G., Obermeier, K., Taylor, K., Morgan, L., Burmi, R.,.. Nicholson, R.I., Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation. International Journal of Cancer 118 (2006), 290–301.
-
(2006)
International Journal of Cancer
, vol.118
, pp. 290-301
-
-
Hiscox, S.1
Jiang, W.G.2
Obermeier, K.3
Taylor, K.4
Morgan, L.5
Burmi, R.6
Nicholson, R.I.7
-
63
-
-
0026095795
-
Structure and functional expression of a human interleukin-8 receptor
-
Holmes, W.E., Lee, J., Kuang, W.J., Rice, G.C., Wood, W.I., Structure and functional expression of a human interleukin-8 receptor. Science 253 (1991), 1278–1280.
-
(1991)
Science
, vol.253
, pp. 1278-1280
-
-
Holmes, W.E.1
Lee, J.2
Kuang, W.J.3
Rice, G.C.4
Wood, W.I.5
-
64
-
-
84879680963
-
The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies
-
Huang, B., Cohen, J.R., Fernando, R.I., Hamilton, D.H., Litzinger, M.T., Hodge, J.W., Palena, C., The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies. Cell Death & Disease, 4, 2013, e682.
-
(2013)
Cell Death & Disease
, vol.4
-
-
Huang, B.1
Cohen, J.R.2
Fernando, R.I.3
Hamilton, D.H.4
Litzinger, M.T.5
Hodge, J.W.6
Palena, C.7
-
65
-
-
84889570568
-
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)
-
Huang, R.Y., Wong, M.K., Tan, T.Z., Kuay, K.T., Ng, A.H., Chung, V.Y., Chu, Y.S., Matsumura, N., Lai, H.C., Lee, Y.F., Sim, W.J., Chai, C., Pietschmann, E., Mori, S., Low, J.J., Choolani, M., Thiery, J.P., An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530). Cell Death & Disease, 4, 2013, e915.
-
(2013)
Cell Death & Disease
, vol.4
, pp. e915
-
-
Huang, R.Y.1
Wong, M.K.2
Tan, T.Z.3
Kuay, K.T.4
Ng, A.H.5
Chung, V.Y.6
Chu, Y.S.7
Matsumura, N.8
Lai, H.C.9
Lee, Y.F.10
Sim, W.J.11
Chai, C.12
Pietschmann, E.13
Mori, S.14
Low, J.J.15
Choolani, M.16
Thiery, J.P.17
-
66
-
-
0036310021
-
Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma
-
Huang, S., Mills, L., Mian, B., Tellez, C., McCarty, M., Yang, X.D.,.. Bar-Eli, M., Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma. The American Journal of Pathology 161 (2002), 125–134.
-
(2002)
The American Journal of Pathology
, vol.161
, pp. 125-134
-
-
Huang, S.1
Mills, L.2
Mian, B.3
Tellez, C.4
McCarty, M.5
Yang, X.D.6
Bar-Eli, M.7
-
67
-
-
84879099298
-
A phase 1 study of a chimeric monoclonal antibody against interleukin-6, siltuximab, combined with docetaxel in patients with metastatic castration-resistant prostate cancer
-
Hudes, G., Tagawa, S.T., Whang, Y.E., Qi, M., Qin, X., Puchalski, T.A.,.. Eisenberger, M., A phase 1 study of a chimeric monoclonal antibody against interleukin-6, siltuximab, combined with docetaxel in patients with metastatic castration-resistant prostate cancer. Investigational New Drugs 31 (2013), 669–676.
-
(2013)
Investigational New Drugs
, vol.31
, pp. 669-676
-
-
Hudes, G.1
Tagawa, S.T.2
Whang, Y.E.3
Qi, M.4
Qin, X.5
Puchalski, T.A.6
Eisenberger, M.7
-
68
-
-
84961221351
-
Genomic and transcriptomic features of response to anti-PD-1 therapy in metastatic melanoma
-
Hugo, W., Zaretsky, J.M., Sun, L., Song, C., Moreno, B.H., Hu-Lieskovan, S.,.. Lo, R.S., Genomic and transcriptomic features of response to anti-PD-1 therapy in metastatic melanoma. Cell 165 (2016), 35–44.
-
(2016)
Cell
, vol.165
, pp. 35-44
-
-
Hugo, W.1
Zaretsky, J.M.2
Sun, L.3
Song, C.4
Moreno, B.H.5
Hu-Lieskovan, S.6
Lo, R.S.7
-
69
-
-
84926622710
-
Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression
-
Huynh, T.P., Barwe, S.P., Lee, S.J., McSpadden, R., Franco, O.E., Hayward, S.W.,.. Rajasekaran, A.K., Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression. PLoS One, 10, 2015, e0122442.
-
(2015)
PLoS One
, vol.10
-
-
Huynh, T.P.1
Barwe, S.P.2
Lee, S.J.3
McSpadden, R.4
Franco, O.E.5
Hayward, S.W.6
Rajasekaran, A.K.7
-
70
-
-
84869838257
-
T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma
-
Imajyo, I., Sugiura, T., Kobayashi, Y., Shimoda, M., Ishii, K., Akimoto, N.,.. Mori, Y., T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma. International Journal of Oncology 41 (2012), 1985–1995.
-
(2012)
International Journal of Oncology
, vol.41
, pp. 1985-1995
-
-
Imajyo, I.1
Sugiura, T.2
Kobayashi, Y.3
Shimoda, M.4
Ishii, K.5
Akimoto, N.6
Mori, Y.7
-
71
-
-
80355139007
-
The antisense oligonucleotide trabedersen (AP 12009) for the targeted inhibition of TGF-beta2
-
Jaschinski, F., Rothhammer, T., Jachimczak, P., Seitz, C., Schneider, A., Schlingensiepen, K.H., The antisense oligonucleotide trabedersen (AP 12009) for the targeted inhibition of TGF-beta2. Current Pharmaceutical Biotechnology 12 (2011), 2203–2213.
-
(2011)
Current Pharmaceutical Biotechnology
, vol.12
, pp. 2203-2213
-
-
Jaschinski, F.1
Rothhammer, T.2
Jachimczak, P.3
Seitz, C.4
Schneider, A.5
Schlingensiepen, K.H.6
-
72
-
-
0030450052
-
The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing
-
Kadowaki, T., Wilder, E., Klingensmith, J., Zachary, K., Perrimon, N., The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes & Development 10 (1996), 3116–3128.
-
(1996)
Genes & Development
, vol.10
, pp. 3116-3128
-
-
Kadowaki, T.1
Wilder, E.2
Klingensmith, J.3
Zachary, K.4
Perrimon, N.5
-
73
-
-
35148825636
-
Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells
-
Kajiyama, H., Shibata, K., Terauchi, M., Yamashita, M., Ino, K., Nawa, A., Kikkawa, F., Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells. International Journal of Oncology 31 (2007), 277–283.
-
(2007)
International Journal of Oncology
, vol.31
, pp. 277-283
-
-
Kajiyama, H.1
Shibata, K.2
Terauchi, M.3
Yamashita, M.4
Ino, K.5
Nawa, A.6
Kikkawa, F.7
-
75
-
-
84922469342
-
Therapeutic uses of anti-interleukin-6 receptor antibody
-
Kang, S., Tanaka, T., Kishimoto, T., Therapeutic uses of anti-interleukin-6 receptor antibody. International Immunology 27 (2015), 21–29.
-
(2015)
International Immunology
, vol.27
, pp. 21-29
-
-
Kang, S.1
Tanaka, T.2
Kishimoto, T.3
-
76
-
-
0023849455
-
Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
-
Kawano, M., Hirano, T., Matsuda, T., Taga, T., Horii, Y., Iwato, K., Asaoku, H., Tang, B., Tanabe, O., Tanaka, H., et al. Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature 332 (1988), 83–85.
-
(1988)
Nature
, vol.332
, pp. 83-85
-
-
Kawano, M.1
Hirano, T.2
Matsuda, T.3
Taga, T.4
Horii, Y.5
Iwato, K.6
Asaoku, H.7
Tang, B.8
Tanabe, O.9
Tanaka, H.10
-
77
-
-
84891641093
-
Monensin induced oxidative stress reduces prostate cancer cell migration and cancer stem cell population
-
V. Lushchak D.V. Gospodaryov InTech
-
Ketola, K., Vuoristo, A., Orešič, M., Kallioniemi, O., Iljin, K., Monensin induced oxidative stress reduces prostate cancer cell migration and cancer stem cell population. Lushchak, V., Gospodaryov, D.V., (eds.) Oxidative stress and diseases, 2012, InTech.
-
(2012)
Oxidative stress and diseases
-
-
Ketola, K.1
Vuoristo, A.2
Orešič, M.3
Kallioniemi, O.4
Iljin, K.5
-
78
-
-
79953690193
-
Brachyury expression predicts poor prognosis at early stages of colorectal cancer
-
Kilic, N., Feldhaus, S., Kilic, E., Tennstedt, P., Wicklein, D., Wasielewski, R.,.. Schumacher, U., Brachyury expression predicts poor prognosis at early stages of colorectal cancer. European Journal of Cancer 47 (2011), 1080–1085.
-
(2011)
European Journal of Cancer
, vol.47
, pp. 1080-1085
-
-
Kilic, N.1
Feldhaus, S.2
Kilic, E.3
Tennstedt, P.4
Wicklein, D.5
Wasielewski, R.6
Schumacher, U.7
-
79
-
-
84908037648
-
Testican-1-mediated epithelial-mesenchymal transition signaling confers acquired resistance to lapatinib in HER2-positive gastric cancer
-
Kim, H.P., Han, S.W., Song, S.H., Jeong, E.G., Lee, M.Y., Hwang, D.,.. Kim, T.Y., Testican-1-mediated epithelial-mesenchymal transition signaling confers acquired resistance to lapatinib in HER2-positive gastric cancer. Oncogene 33 (2014), 3334–3341.
-
(2014)
Oncogene
, vol.33
, pp. 3334-3341
-
-
Kim, H.P.1
Han, S.W.2
Song, S.H.3
Jeong, E.G.4
Lee, M.Y.5
Hwang, D.6
Kim, T.Y.7
-
80
-
-
85033680828
-
On the role of mechanics in driving mesenchymal-to-epithelial transitions
-
Kim, H.Y., Jackson, T.R., Davidson, L.A., On the role of mechanics in driving mesenchymal-to-epithelial transitions. Seminars in Cell & Developmental Biology, 2016.
-
(2016)
Seminars in Cell & Developmental Biology
-
-
Kim, H.Y.1
Jackson, T.R.2
Davidson, L.A.3
-
81
-
-
0030048490
-
Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils
-
Knall, C., Young, S., Nick, J.A., Buhl, A.M., Worthen, G.S., Johnson, G.L., Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils. The Journal of Biological Chemistry 271 (1996), 2832–2838.
-
(1996)
The Journal of Biological Chemistry
, vol.271
, pp. 2832-2838
-
-
Knall, C.1
Young, S.2
Nick, J.A.3
Buhl, A.M.4
Worthen, G.S.5
Johnson, G.L.6
-
82
-
-
84920973530
-
PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells
-
Kolev, V.N., Wright, Q.G., Vidal, C.M., Ring, J.E., Shapiro, I.M., Ricono, J.,.. Xu, Q., PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells. Cancer Research 75 (2015), 446–455.
-
(2015)
Cancer Research
, vol.75
, pp. 446-455
-
-
Kolev, V.N.1
Wright, Q.G.2
Vidal, C.M.3
Ring, J.E.4
Shapiro, I.M.5
Ricono, J.6
Xu, Q.7
-
83
-
-
84925534854
-
Novel clinical therapeutics targeting the epithelial to mesenchymal transition
-
Kothari, A.N., Mi, Z., Zapf, M., Kuo, P.C., Novel clinical therapeutics targeting the epithelial to mesenchymal transition. Clinical and Translational Medicine, 3, 2014, 35.
-
(2014)
Clinical and Translational Medicine
, vol.3
, pp. 35
-
-
Kothari, A.N.1
Mi, Z.2
Zapf, M.3
Kuo, P.C.4
-
84
-
-
70349859809
-
Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
-
Kurrey, N.K., Jalgaonkar, S.P., Joglekar, A.V., Ghanate, A.D., Chaskar, P.D., Doiphode, R.Y., Bapat, S.A., Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells 27 (2009), 2059–2068.
-
(2009)
Stem Cells
, vol.27
, pp. 2059-2068
-
-
Kurrey, N.K.1
Jalgaonkar, S.P.2
Joglekar, A.V.3
Ghanate, A.D.4
Chaskar, P.D.5
Doiphode, R.Y.6
Bapat, S.A.7
-
85
-
-
84884524473
-
An autocrine loop between TGF-beta1 and the transcription factor brachyury controls the transition of human carcinoma cells into a mesenchymal phenotype
-
Larocca, C., Cohen, J.R., Fernando, R.I., Huang, B., Hamilton, D.H., Palena, C., An autocrine loop between TGF-beta1 and the transcription factor brachyury controls the transition of human carcinoma cells into a mesenchymal phenotype. Molecular Cancer Therapeutics 12 (2013), 1805–1815.
-
(2013)
Molecular Cancer Therapeutics
, vol.12
, pp. 1805-1815
-
-
Larocca, C.1
Cohen, J.R.2
Fernando, R.I.3
Huang, B.4
Hamilton, D.H.5
Palena, C.6
-
86
-
-
84919456263
-
Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28
-
Le, P.N., McDermott, J.D., Jimeno, A., Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28. Pharmacology & Therapeutics 146 (2015), 1–11.
-
(2015)
Pharmacology & Therapeutics
, vol.146
, pp. 1-11
-
-
Le, P.N.1
McDermott, J.D.2
Jimeno, A.3
-
87
-
-
84903815776
-
The dual role of TGFbeta in human cancer: from tumor suppression to cancer metastasis
-
Lebrun, J.J., The dual role of TGFbeta in human cancer: from tumor suppression to cancer metastasis. ISRN Molecular Biology, 2012, 2012, 381428.
-
(2012)
ISRN Molecular Biology
, vol.2012
, pp. 381428
-
-
Lebrun, J.J.1
-
88
-
-
84908185262
-
Safely targeting cancer stem cells via selective catenin coactivator antagonism
-
Lenz, H.J., Kahn, M., Safely targeting cancer stem cells via selective catenin coactivator antagonism. Cancer Science 105 (2014), 1087–1092.
-
(2014)
Cancer Science
, vol.105
, pp. 1087-1092
-
-
Lenz, H.J.1
Kahn, M.2
-
89
-
-
84865839326
-
Epithelial-mesenchymal transitions: insights from development
-
Lim, J., Thiery, J.P., Epithelial-mesenchymal transitions: insights from development. Development 139 (2012), 3471–3486.
-
(2012)
Development
, vol.139
, pp. 3471-3486
-
-
Lim, J.1
Thiery, J.P.2
-
90
-
-
84929591022
-
IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer
-
Liu, Y.N., Chang, T.H., Tsai, M.F., Wu, S.G., Tsai, T.H., Chen, H.Y.,.. Shih, J.Y., IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer. Oncotarget 6 (2015), 10415–10431.
-
(2015)
Oncotarget
, vol.6
, pp. 10415-10431
-
-
Liu, Y.N.1
Chang, T.H.2
Tsai, M.F.3
Wu, S.G.4
Tsai, T.H.5
Chen, H.Y.6
Shih, J.Y.7
-
91
-
-
84890281677
-
Targeting Wnt-driven cancer through the inhibition of porcupine by LGK974
-
Liu, J., Pan, S., Hsieh, M.H., Ng, N., Sun, F., Wang, T.,.. Harris, J.L., Targeting Wnt-driven cancer through the inhibition of porcupine by LGK974. Proceedings of the National Academy of Sciences of the United States of America 110 (2013), 20224–20229.
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, pp. 20224-20229
-
-
Liu, J.1
Pan, S.2
Hsieh, M.H.3
Ng, N.4
Sun, F.5
Wang, T.6
Harris, J.L.7
-
92
-
-
33644834687
-
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines
-
Lombaerts, M., van Wezel, T., Philippo, K., Dierssen, J.W., Zimmerman, R.M., Oosting, J.,.. Cleton-Jansen, A.M., E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines. British Journal of Cancer 94 (2006), 661–671.
-
(2006)
British Journal of Cancer
, vol.94
, pp. 661-671
-
-
Lombaerts, M.1
van Wezel, T.2
Philippo, K.3
Dierssen, J.W.4
Zimmerman, R.M.5
Oosting, J.6
Cleton-Jansen, A.M.7
-
93
-
-
84855222588
-
Antibody targeting of TGF-beta in cancer patients
-
Lonning, S., Mannick, J., McPherson, J.M., Antibody targeting of TGF-beta in cancer patients. Current Pharmaceutical Biotechnology 12 (2011), 2176–2189.
-
(2011)
Current Pharmaceutical Biotechnology
, vol.12
, pp. 2176-2189
-
-
Lonning, S.1
Mannick, J.2
McPherson, J.M.3
-
94
-
-
84978393973
-
Epithelial-mesenchymal transition is associated with a distinct tumor microenvironment including elevation of inflammatory signals and multiple immune checkpoints in lung adenocarcinoma
-
Lou, Y., Diao, L., Cuentas, E.R., Denning, W.L., Chen, L., Fan, Y.H.,.. Gibbons, D.L., Epithelial-mesenchymal transition is associated with a distinct tumor microenvironment including elevation of inflammatory signals and multiple immune checkpoints in lung adenocarcinoma. Clinical Cancer Research 22 (2016), 3630–3642.
-
(2016)
Clinical Cancer Research
, vol.22
, pp. 3630-3642
-
-
Lou, Y.1
Diao, L.2
Cuentas, E.R.3
Denning, W.L.4
Chen, L.5
Fan, Y.H.6
Gibbons, D.L.7
-
95
-
-
80052012674
-
Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells
-
Lu, D., Choi, M.Y., Yu, J., Castro, J.E., Kipps, T.J., Carson, D.A., Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells. Proceedings of the National Academy of Sciences of the United States of America 108 (2011), 13253–13257.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 13253-13257
-
-
Lu, D.1
Choi, M.Y.2
Yu, J.3
Castro, J.E.4
Kipps, T.J.5
Carson, D.A.6
-
96
-
-
34547112049
-
Interleukin-8 signaling promotes translational regulation of cyclin D in androgen-independent prostate cancer cells
-
MacManus, C.F., Pettigrew, J., Seaton, A., Wilson, C., Maxwell, P.J., Berlingeri, S.,.. Waugh, D.J., Interleukin-8 signaling promotes translational regulation of cyclin D in androgen-independent prostate cancer cells. Molecular Cancer Research 5 (2007), 737–748.
-
(2007)
Molecular Cancer Research
, vol.5
, pp. 737-748
-
-
MacManus, C.F.1
Pettigrew, J.2
Seaton, A.3
Wilson, C.4
Maxwell, P.J.5
Berlingeri, S.6
Waugh, D.J.7
-
97
-
-
84861178107
-
Clinical evaluation of TRICOM vector therapeutic cancer vaccines
-
Madan, R.A., Bilusic, M., Heery, C., Schlom, J., Gulley, J.L., Clinical evaluation of TRICOM vector therapeutic cancer vaccines. Seminars in Oncology 39 (2012), 296–304.
-
(2012)
Seminars in Oncology
, vol.39
, pp. 296-304
-
-
Madan, R.A.1
Bilusic, M.2
Heery, C.3
Schlom, J.4
Gulley, J.L.5
-
98
-
-
84958954805
-
A patient-derived, pan-cancer EMT signature identifies global molecular alterations and immune target enrichment following epithelial-to-mesenchymal transition
-
Mak, M.P., Tong, P., Diao, L., Cardnell, R.J., Gibbons, D.L., William, W.N.,.. Byers, L.A., A patient-derived, pan-cancer EMT signature identifies global molecular alterations and immune target enrichment following epithelial-to-mesenchymal transition. Clinical Cancer Research 22 (2016), 609–620.
-
(2016)
Clinical Cancer Research
, vol.22
, pp. 609-620
-
-
Mak, M.P.1
Tong, P.2
Diao, L.3
Cardnell, R.J.4
Gibbons, D.L.5
William, W.N.6
Byers, L.A.7
-
99
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani, S.A., Guo, W., Liao, M.J., Eaton, E.N., Ayyanan, A., Zhou, A.Y.,.. Weinberg, R.A., The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133 (2008), 704–715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Weinberg, R.A.7
-
100
-
-
79959956046
-
The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors
-
Marotta, L.L., Almendro, V., Marusyk, A., Shipitsin, M., Schemme, J., Walker, S.R.,.. Polyak, K., The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors. The Journal of Clinical Investigation 121 (2011), 2723–2735.
-
(2011)
The Journal of Clinical Investigation
, vol.121
, pp. 2723-2735
-
-
Marotta, L.L.1
Almendro, V.2
Marusyk, A.3
Shipitsin, M.4
Schemme, J.5
Walker, S.R.6
Polyak, K.7
-
101
-
-
47549090432
-
TGFbeta in cancer
-
Massague, J., TGFbeta in cancer. Cell 134 (2008), 215–230.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
102
-
-
79961023271
-
Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition
-
McDonald, O.G., Wu, H., Timp, W., Doi, A., Feinberg, A.P., Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition. Nature Structural & Molecular Biology 18 (2011), 867–874.
-
(2011)
Nature Structural & Molecular Biology
, vol.18
, pp. 867-874
-
-
McDonald, O.G.1
Wu, H.2
Timp, W.3
Doi, A.4
Feinberg, A.P.5
-
103
-
-
35848963863
-
Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition
-
Mejlvang, J., Kriajevska, M., Vandewalle, C., Chernova, T., Sayan, A.E., Berx, G.,.. Tulchinsky, E., Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition. Molecular Biology of the Cell 18 (2007), 4615–4624.
-
(2007)
Molecular Biology of the Cell
, vol.18
, pp. 4615-4624
-
-
Mejlvang, J.1
Kriajevska, M.2
Vandewalle, C.3
Chernova, T.4
Sayan, A.E.5
Berx, G.6
Tulchinsky, E.7
-
104
-
-
0042525815
-
Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB
-
Mian, B.M., Dinney, C.P., Bermejo, C.E., Sweeney, P., Tellez, C., Yang, X.D.,.. Bar-Eli, M., Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB. Clinical Cancer Research 9 (2003), 3167–3175.
-
(2003)
Clinical Cancer Research
, vol.9
, pp. 3167-3175
-
-
Mian, B.M.1
Dinney, C.P.2
Bermejo, C.E.3
Sweeney, P.4
Tellez, C.5
Yang, X.D.6
Bar-Eli, M.7
-
105
-
-
84902580297
-
Interleukin-6-induced epithelial-mesenchymal transition through signal transducer and activator of transcription 3 in human cervical carcinoma
-
Miao, J.W., Liu, L.J., Huang, J., Interleukin-6-induced epithelial-mesenchymal transition through signal transducer and activator of transcription 3 in human cervical carcinoma. International Journal of Oncology 45 (2014), 165–176.
-
(2014)
International Journal of Oncology
, vol.45
, pp. 165-176
-
-
Miao, J.W.1
Liu, L.J.2
Huang, J.3
-
106
-
-
77954860342
-
Epithelial-mesenchymal transition in cancer: Parallels between normal development and tumor progression
-
Micalizzi, D.S., Farabaugh, S.M., Ford, H.L., Epithelial-mesenchymal transition in cancer: Parallels between normal development and tumor progression. Journal of Mammary Gland Biology and Neoplasia 15 (2010), 117–134.
-
(2010)
Journal of Mammary Gland Biology and Neoplasia
, vol.15
, pp. 117-134
-
-
Micalizzi, D.S.1
Farabaugh, S.M.2
Ford, H.L.3
-
107
-
-
0017158502
-
Salinomycin effects on mitochondrial ion translocation and respiration
-
Mitani, M., Yamanishi, T., Miyazaki, Y., Otake, N., Salinomycin effects on mitochondrial ion translocation and respiration. Antimicrobial Agents and Chemotherapy 9 (1976), 655–660.
-
(1976)
Antimicrobial Agents and Chemotherapy
, vol.9
, pp. 655-660
-
-
Mitani, M.1
Yamanishi, T.2
Miyazaki, Y.3
Otake, N.4
-
108
-
-
84897566294
-
Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFbeta) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma
-
Morris, J.C., Tan, A.R., Olencki, T.E., Shapiro, G.I., Dezube, B.J., Reiss, M.,.. Lawrence, D.P., Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFbeta) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma. PLoS One, 9, 2014, e90353.
-
(2014)
PLoS One
, vol.9
-
-
Morris, J.C.1
Tan, A.R.2
Olencki, T.E.3
Shapiro, G.I.4
Dezube, B.J.5
Reiss, M.6
Lawrence, D.P.7
-
109
-
-
84923651864
-
Targeting a cell state common to triple-negative breast cancers
-
Muellner, M.K., Mair, B., Ibrahim, Y., Kerzendorfer, C., Lechtermann, H., Trefzer, C.,.. Nijman, S.M., Targeting a cell state common to triple-negative breast cancers. Molecular Systems Biology, 11, 2015, 789.
-
(2015)
Molecular Systems Biology
, vol.11
, pp. 789
-
-
Muellner, M.K.1
Mair, B.2
Ibrahim, Y.3
Kerzendorfer, C.4
Lechtermann, H.5
Trefzer, C.6
Nijman, S.M.7
-
110
-
-
84871395763
-
Salinomycin as a drug for targeting human cancer stem cells
-
Naujokat, C., Steinhart, R., Salinomycin as a drug for targeting human cancer stem cells. Journal of Biomedicine & Biotechnology, 2012, 2012, 950658.
-
(2012)
Journal of Biomedicine & Biotechnology
, vol.2012
, pp. 950658
-
-
Naujokat, C.1
Steinhart, R.2
-
111
-
-
84866325625
-
The epithelial-mesenchymal transition under control: Global programs to regulate epithelial plasticity
-
Nieto, M.A., Cano, A., The epithelial-mesenchymal transition under control: Global programs to regulate epithelial plasticity. Seminars in Cancer Biology 22 (2012), 361–368.
-
(2012)
Seminars in Cancer Biology
, vol.22
, pp. 361-368
-
-
Nieto, M.A.1
Cano, A.2
-
112
-
-
0021270667
-
Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15
-
Nusse, R., van Ooyen, A., Cox, D., Fung, Y.K., Varmus, H., Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature 307 (1984), 131–136.
-
(1984)
Nature
, vol.307
, pp. 131-136
-
-
Nusse, R.1
van Ooyen, A.2
Cox, D.3
Fung, Y.K.4
Varmus, H.5
-
113
-
-
0031014669
-
Interleukin-6 as a paracrine and autocrine growth factor in human prostatic carcinoma cells in vitro
-
Okamoto, M., Lee, C., Oyasu, R., Interleukin-6 as a paracrine and autocrine growth factor in human prostatic carcinoma cells in vitro. Cancer Research 57 (1997), 141–146.
-
(1997)
Cancer Research
, vol.57
, pp. 141-146
-
-
Okamoto, M.1
Lee, C.2
Oyasu, R.3
-
114
-
-
58149236744
-
Roles of TGFbeta in metastasis
-
Padua, D., Massague, J., Roles of TGFbeta in metastasis. Cell Research 19 (2009), 89–102.
-
(2009)
Cell Research
, vol.19
, pp. 89-102
-
-
Padua, D.1
Massague, J.2
-
115
-
-
84952714993
-
Immune targeting of tumor epithelial-mesenchymal transition via brachyury-based vaccines
-
Palena, C., Hamilton, D.H., Immune targeting of tumor epithelial-mesenchymal transition via brachyury-based vaccines. Advances in Cancer Research 128 (2015), 69–93.
-
(2015)
Advances in Cancer Research
, vol.128
, pp. 69-93
-
-
Palena, C.1
Hamilton, D.H.2
-
116
-
-
84863707423
-
Influence of IL-8 on the epithelial-mesenchymal transition and the tumor microenvironment
-
Palena, C., Hamilton, D.H., Fernando, R.I., Influence of IL-8 on the epithelial-mesenchymal transition and the tumor microenvironment. Future Oncology 8 (2012), 713–722.
-
(2012)
Future Oncology
, vol.8
, pp. 713-722
-
-
Palena, C.1
Hamilton, D.H.2
Fernando, R.I.3
-
117
-
-
34247887629
-
The human T-box mesodermal transcription factor Brachyury is a candidate target for T-cell-mediated cancer immunotherapy
-
Palena, C., Polev, D.E., Tsang, K.Y., Fernando, R.I., Litzinger, M., Krukovskaya, L.L.,.. Schlom, J., The human T-box mesodermal transcription factor Brachyury is a candidate target for T-cell-mediated cancer immunotherapy. Clinical Cancer Research 13 (2007), 2471–2478.
-
(2007)
Clinical Cancer Research
, vol.13
, pp. 2471-2478
-
-
Palena, C.1
Polev, D.E.2
Tsang, K.Y.3
Fernando, R.I.4
Litzinger, M.5
Krukovskaya, L.L.6
Schlom, J.7
-
118
-
-
84905171394
-
Overexpression of the EMT driver brachyury in breast carcinomas: Association with poor prognosis
-
Palena, C., Roselli, M., Litzinger, M.T., Ferroni, P., Costarelli, L., Spila, A.,.. Guadagni, F., Overexpression of the EMT driver brachyury in breast carcinomas: Association with poor prognosis. Journal of the National Cancer Institute, 106, 2014.
-
(2014)
Journal of the National Cancer Institute
, vol.106
-
-
Palena, C.1
Roselli, M.2
Litzinger, M.T.3
Ferroni, P.4
Costarelli, L.5
Spila, A.6
Guadagni, F.7
-
119
-
-
84903768676
-
Tackling the cancer stem cells - What challenges do they pose?
-
Pattabiraman, D.R., Weinberg, R.A., Tackling the cancer stem cells - What challenges do they pose?. Nature Reviews. Drug Discovery 13 (2014), 497–512.
-
(2014)
Nature Reviews. Drug Discovery
, vol.13
, pp. 497-512
-
-
Pattabiraman, D.R.1
Weinberg, R.A.2
-
120
-
-
84891713908
-
Cell volume regulation in epithelial physiology and cancer
-
Pedersen, S.F., Hoffmann, E.K., Novak, I., Cell volume regulation in epithelial physiology and cancer. Frontiers in Physiology, 4, 2013, 233.
-
(2013)
Frontiers in Physiology
, vol.4
, pp. 233
-
-
Pedersen, S.F.1
Hoffmann, E.K.2
Novak, I.3
-
121
-
-
0346363757
-
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
-
Peinado, H., Ballestar, E., Esteller, M., Cano, A., Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Molecular and Cellular Biology 24 (2004), 306–319.
-
(2004)
Molecular and Cellular Biology
, vol.24
, pp. 306-319
-
-
Peinado, H.1
Ballestar, E.2
Esteller, M.3
Cano, A.4
-
122
-
-
79960715096
-
Increased levels of circulating interleukin 6, interleukin 8, C-reactive protein, and risk of lung cancer
-
Pine, S.R., Mechanic, L.E., Enewold, L., Chaturvedi, A.K., Katki, H.A., Zheng, Y.L.,.. Harris, C.C., Increased levels of circulating interleukin 6, interleukin 8, C-reactive protein, and risk of lung cancer. Journal of the National Cancer Institute 103 (2011), 1112–1122.
-
(2011)
Journal of the National Cancer Institute
, vol.103
, pp. 1112-1122
-
-
Pine, S.R.1
Mechanic, L.E.2
Enewold, L.3
Chaturvedi, A.K.4
Katki, H.A.5
Zheng, Y.L.6
Harris, C.C.7
-
123
-
-
84929678112
-
The embryonic Brachyury transcription factor is a novel biomarker of GIST aggressiveness and poor survival
-
Pinto, F., Campanella, N.C., Abrahao-Machado, L.F., Scapulatempo-Neto, C., de Oliveira, A.T., Brito, M.J.,.. Reis, R.M., The embryonic Brachyury transcription factor is a novel biomarker of GIST aggressiveness and poor survival. Gastric Cancer 19 (2016), 651–659.
-
(2016)
Gastric Cancer
, vol.19
, pp. 651-659
-
-
Pinto, F.1
Campanella, N.C.2
Abrahao-Machado, L.F.3
Scapulatempo-Neto, C.4
de Oliveira, A.T.5
Brito, M.J.6
Reis, R.M.7
-
124
-
-
84907916641
-
T-box transcription factor brachyury is associated with prostate cancer progression and aggressiveness
-
Pinto, F., Pertega-Gomes, N., Pereira, M.S., Vizcaino, J.R., Monteiro, P., Henrique, R.M.,.. Reis, R.M., T-box transcription factor brachyury is associated with prostate cancer progression and aggressiveness. Clinical Cancer Research 20 (2014), 4949–4961.
-
(2014)
Clinical Cancer Research
, vol.20
, pp. 4949-4961
-
-
Pinto, F.1
Pertega-Gomes, N.2
Pereira, M.S.3
Vizcaino, J.R.4
Monteiro, P.5
Henrique, R.M.6
Reis, R.M.7
-
125
-
-
84901008792
-
Targeting PI3K/Akt/mTOR signaling in cancer
-
Porta, C., Paglino, C., Mosca, A., Targeting PI3K/Akt/mTOR signaling in cancer. Frontiers in Oncology, 4, 2014, 64.
-
(2014)
Frontiers in Oncology
, vol.4
, pp. 64
-
-
Porta, C.1
Paglino, C.2
Mosca, A.3
-
126
-
-
84923078390
-
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
-
Powles, T., Eder, J.P., Fine, G.D., Braiteh, F.S., Loriot, Y., Cruz, C.,.. Vogelzang, N.J., MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature 515 (2014), 558–562.
-
(2014)
Nature
, vol.515
, pp. 558-562
-
-
Powles, T.1
Eder, J.P.2
Fine, G.D.3
Braiteh, F.S.4
Loriot, Y.5
Cruz, C.6
Vogelzang, N.J.7
-
127
-
-
78049308800
-
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
-
Prat, A., Parker, J.S., Karginova, O., Fan, C., Livasy, C., Herschkowitz, J.I.,.. Perou, C.M., Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Research, 12, 2010, R68.
-
(2010)
Breast Cancer Research
, vol.12
, pp. R68
-
-
Prat, A.1
Parker, J.S.2
Karginova, O.3
Fan, C.4
Livasy, C.5
Herschkowitz, J.I.6
Perou, C.M.7
-
128
-
-
84942878342
-
Interleukin-6 prevents the initiation but enhances the progression of lung cancer
-
Qu, Z., Sun, F., Zhou, J., Li, L., Shapiro, S.D., Xiao, G., Interleukin-6 prevents the initiation but enhances the progression of lung cancer. Cancer Research 75 (2015), 3209–3215.
-
(2015)
Cancer Research
, vol.75
, pp. 3209-3215
-
-
Qu, Z.1
Sun, F.2
Zhou, J.3
Li, L.4
Shapiro, S.D.5
Xiao, G.6
-
129
-
-
77953382455
-
Na,K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis
-
Rajasekaran, S.A., Huynh, T.P., Wolle, D.G., Espineda, C.E., Inge, L.J., Skay, A.,.. Rajasekaran, A.K., Na,K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis. Molecular Cancer Therapeutics 9 (2010), 1515–1524.
-
(2010)
Molecular Cancer Therapeutics
, vol.9
, pp. 1515-1524
-
-
Rajasekaran, S.A.1
Huynh, T.P.2
Wolle, D.G.3
Espineda, C.E.4
Inge, L.J.5
Skay, A.6
Rajasekaran, A.K.7
-
130
-
-
84856088337
-
EMT and dissemination precede pancreatic tumor formation
-
Rhim, A.D., Mirek, E.T., Aiello, N.M., Maitra, A., Bailey, J.M., McAllister, F.,.. Stanger, B.Z., EMT and dissemination precede pancreatic tumor formation. Cell 148 (2012), 349–361.
-
(2012)
Cell
, vol.148
, pp. 349-361
-
-
Rhim, A.D.1
Mirek, E.T.2
Aiello, N.M.3
Maitra, A.4
Bailey, J.M.5
McAllister, F.6
Stanger, B.Z.7
-
131
-
-
84964341647
-
Association of pembrolizumab with tumor response and survival among patients with advanced melanoma
-
Ribas, A., Hamid, O., Daud, A., Hodi, F.S., Wolchok, J.D., Kefford, R.,.. Robert, C., Association of pembrolizumab with tumor response and survival among patients with advanced melanoma. JAMA 315 (2016), 1600–1609.
-
(2016)
JAMA
, vol.315
, pp. 1600-1609
-
-
Ribas, A.1
Hamid, O.2
Daud, A.3
Hodi, F.S.4
Wolchok, J.D.5
Kefford, R.6
Robert, C.7
-
132
-
-
77953126613
-
The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor
-
Riccioni, R., Dupuis, M.L., Bernabei, M., Petrucci, E., Pasquini, L., Mariani, G.,.. Testa, U., The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor. Blood Cells, Molecules & Diseases 45 (2010), 86–92.
-
(2010)
Blood Cells, Molecules & Diseases
, vol.45
, pp. 86-92
-
-
Riccioni, R.1
Dupuis, M.L.2
Bernabei, M.3
Petrucci, E.4
Pasquini, L.5
Mariani, G.6
Testa, U.7
-
133
-
-
84989925237
-
ZEB1-mediated melanoma cell plasticity enhances resistance to MAPK inhibitors
-
(pii: e201505971)
-
Richard, G., Dalle, S., Monet, M.A., Ligier, M., Boespflug, A., Pommier, R.M.,.. Caramel, J., ZEB1-mediated melanoma cell plasticity enhances resistance to MAPK inhibitors. EMBO Molecular Medicine, 2016 (pii: e201505971).
-
(2016)
EMBO Molecular Medicine
-
-
Richard, G.1
Dalle, S.2
Monet, M.A.3
Ligier, M.4
Boespflug, A.5
Pommier, R.M.6
Caramel, J.7
-
134
-
-
84961288435
-
First-in-human dose study of the novel transforming growth factor-beta receptor I kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma
-
Rodon, J., Carducci, M.A., Sepulveda-Sanchez, J.M., Azaro, A., Calvo, E., Seoane, J.,.. Baselga, J., First-in-human dose study of the novel transforming growth factor-beta receptor I kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma. Clinical Cancer Research 21 (2015), 553–560.
-
(2015)
Clinical Cancer Research
, vol.21
, pp. 553-560
-
-
Rodon, J.1
Carducci, M.A.2
Sepulveda-Sanchez, J.M.3
Azaro, A.4
Calvo, E.5
Seoane, J.6
Baselga, J.7
-
135
-
-
84897561550
-
IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
-
Rokavec, M., Oner, M.G., Li, H., Jackstadt, R., Jiang, L., Lodygin, D.,.. Hermeking, H., IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. The Journal of Clinical Investigation 124 (2014), 1853–1867.
-
(2014)
The Journal of Clinical Investigation
, vol.124
, pp. 1853-1867
-
-
Rokavec, M.1
Oner, M.G.2
Li, H.3
Jackstadt, R.4
Jiang, L.5
Lodygin, D.6
Hermeking, H.7
-
136
-
-
0030825407
-
Chemokines
-
Rollins, B.J., Chemokines. Blood 90 (1997), 909–928.
-
(1997)
Blood
, vol.90
, pp. 909-928
-
-
Rollins, B.J.1
-
137
-
-
84863955851
-
Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: An opportunity for novel interventions against lung cancer
-
Roselli, M., Fernando, R.I., Guadagni, F., Spila, A., Alessandroni, J., Palmirotta, R.,.. Palena, C., Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: An opportunity for novel interventions against lung cancer. Clinical Cancer Research 18 (2012), 3868–3879.
-
(2012)
Clinical Cancer Research
, vol.18
, pp. 3868-3879
-
-
Roselli, M.1
Fernando, R.I.2
Guadagni, F.3
Spila, A.4
Alessandroni, J.5
Palmirotta, R.6
Palena, C.7
-
138
-
-
84959577118
-
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: A single-arm, multicentre, phase 2 trial
-
Rosenberg, J.E., Hoffman-Censits, J., Powles, T., van der Heijden, M.S., Balar, A.V., Necchi, A.,.. Dreicer, R., Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: A single-arm, multicentre, phase 2 trial. Lancet 387 (2016), 1909–1920.
-
(2016)
Lancet
, vol.387
, pp. 1909-1920
-
-
Rosenberg, J.E.1
Hoffman-Censits, J.2
Powles, T.3
van der Heijden, M.S.4
Balar, A.V.5
Necchi, A.6
Dreicer, R.7
-
139
-
-
0037455841
-
Circulating interleukin-6 predicts survival in patients with metastatic breast cancer
-
Salgado, R., Junius, S., Benoy, I., Van Dam, P., Vermeulen, P., Van Marck, E.,.. Dirix, L.Y., Circulating interleukin-6 predicts survival in patients with metastatic breast cancer. International Journal of Cancer 103 (2003), 642–646.
-
(2003)
International Journal of Cancer
, vol.103
, pp. 642-646
-
-
Salgado, R.1
Junius, S.2
Benoy, I.3
Van Dam, P.4
Vermeulen, P.5
Van Marck, E.6
Dirix, L.Y.7
-
140
-
-
84904257935
-
Wilms’ tumor protein induces an epithelial-mesenchymal hybrid differentiation state in clear cell renal cell carcinoma
-
Sampson, V.B., David, J.M., Puig, I., Patil, P.U., de Herreros, A.G., Thomas, G.V., Rajasekaran, A.K., Wilms’ tumor protein induces an epithelial-mesenchymal hybrid differentiation state in clear cell renal cell carcinoma. PLoS One, 9, 2014, e102041.
-
(2014)
PLoS One
, vol.9
-
-
Sampson, V.B.1
David, J.M.2
Puig, I.3
Patil, P.U.4
de Herreros, A.G.5
Thomas, G.V.6
Rajasekaran, A.K.7
-
141
-
-
83655201491
-
BRACHYURY confers cancer stem cell characteristics on colorectal cancer cells
-
Sarkar, D., Shields, B., Davies, M.L., Muller, J., Wakeman, J.A., BRACHYURY confers cancer stem cell characteristics on colorectal cancer cells. International Journal of Cancer 130 (2012), 328–337.
-
(2012)
International Journal of Cancer
, vol.130
, pp. 328-337
-
-
Sarkar, D.1
Shields, B.2
Davies, M.L.3
Muller, J.4
Wakeman, J.A.5
-
142
-
-
84926135569
-
Epithelial-mesenchymal transitions: From cell plasticity to concept elasticity
-
Savagner, P., Epithelial-mesenchymal transitions: From cell plasticity to concept elasticity. Current Topics in Developmental Biology 112 (2015), 273–300.
-
(2015)
Current Topics in Developmental Biology
, vol.112
, pp. 273-300
-
-
Savagner, P.1
-
143
-
-
80051495448
-
Transcription factors that mediate epithelial-mesenchymal transition lead to multidrug resistance by upregulating ABC transporters
-
Saxena, M., Stephens, M.A., Pathak, H., Rangarajan, A., Transcription factors that mediate epithelial-mesenchymal transition lead to multidrug resistance by upregulating ABC transporters. Cell Death & Disease, 2, 2011, e179.
-
(2011)
Cell Death & Disease
, vol.2
-
-
Saxena, M.1
Stephens, M.A.2
Pathak, H.3
Rangarajan, A.4
-
144
-
-
84934327825
-
Molecular portraits of epithelial, mesenchymal, and hybrid States in lung adenocarcinoma and their relevance to survival
-
Schliekelman, M.J., Taguchi, A., Zhu, J., Dai, X., Rodriguez, J., Celiktas, M.,.. Hanash, S.M., Molecular portraits of epithelial, mesenchymal, and hybrid States in lung adenocarcinoma and their relevance to survival. Cancer Research 75 (2015), 1789–1800.
-
(2015)
Cancer Research
, vol.75
, pp. 1789-1800
-
-
Schliekelman, M.J.1
Taguchi, A.2
Zhu, J.3
Dai, X.4
Rodriguez, J.5
Celiktas, M.6
Hanash, S.M.7
-
145
-
-
79956217912
-
Transforming growth factor-beta 2 gene silencing with trabedersen (AP 12009) in pancreatic cancer
-
Schlingensiepen, K.H., Jaschinski, F., Lang, S.A., Moser, C., Geissler, E.K., Schlitt, H.J.,.. Schneider, A., Transforming growth factor-beta 2 gene silencing with trabedersen (AP 12009) in pancreatic cancer. Cancer Science 102 (2011), 1193–1200.
-
(2011)
Cancer Science
, vol.102
, pp. 1193-1200
-
-
Schlingensiepen, K.H.1
Jaschinski, F.2
Lang, S.A.3
Moser, C.4
Geissler, E.K.5
Schlitt, H.J.6
Schneider, A.7
-
146
-
-
84901502933
-
Therapeutic cancer vaccines
-
Schlom, J., Hodge, J.W., Palena, C., Tsang, K.Y., Jochems, C., Greiner, J.W.,.. Gulley, J.L., Therapeutic cancer vaccines. Advances in Cancer Research 121 (2014), 67–124.
-
(2014)
Advances in Cancer Research
, vol.121
, pp. 67-124
-
-
Schlom, J.1
Hodge, J.W.2
Palena, C.3
Tsang, K.Y.4
Jochems, C.5
Greiner, J.W.6
Gulley, J.L.7
-
147
-
-
84940757323
-
Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients
-
Serova, M., Tijeras-Raballand, A., Dos Santos, C., Albuquerque, M., Paradis, V., Neuzillet, C.,.. de Gramont, A., Effects of TGF-beta signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients. Oncotarget 6 (2015), 21614–21627.
-
(2015)
Oncotarget
, vol.6
, pp. 21614-21627
-
-
Serova, M.1
Tijeras-Raballand, A.2
Dos Santos, C.3
Albuquerque, M.4
Paradis, V.5
Neuzillet, C.6
de Gramont, A.7
-
148
-
-
36349006961
-
Development and characterization of gemcitabine-resistant pancreatic tumor cells
-
Shah, A.N., Summy, J.M., Zhang, J., Park, S.I., Parikh, N.U., Gallick, G.E., Development and characterization of gemcitabine-resistant pancreatic tumor cells. Annals of Surgical Oncology 14 (2007), 3629–3637.
-
(2007)
Annals of Surgical Oncology
, vol.14
, pp. 3629-3637
-
-
Shah, A.N.1
Summy, J.M.2
Zhang, J.3
Park, S.I.4
Parikh, N.U.5
Gallick, G.E.6
-
149
-
-
3042813438
-
Effects of monensin liposomes on the cytotoxicity, apoptosis and expression of multidrug resistance genes in doxorubicin-resistant human breast tumour (MCF-7/dox) cell-line
-
Shaik, M.S., Chatterjee, A., Singh, M., Effects of monensin liposomes on the cytotoxicity, apoptosis and expression of multidrug resistance genes in doxorubicin-resistant human breast tumour (MCF-7/dox) cell-line. The Journal of Pharmacy and Pharmacology 56 (2004), 899–907.
-
(2004)
The Journal of Pharmacy and Pharmacology
, vol.56
, pp. 899-907
-
-
Shaik, M.S.1
Chatterjee, A.2
Singh, M.3
-
150
-
-
84987788582
-
IL-6 secreted from cancer-associated fibroblasts mediates chemoresistance in NSCLC by increasing epithelial-mesenchymal transition signaling
-
Shintani, Y., Fujiwara, A., Kimura, T., Kawamura, T., Funaki, S., Minami, M., Okumura, M., IL-6 secreted from cancer-associated fibroblasts mediates chemoresistance in NSCLC by increasing epithelial-mesenchymal transition signaling. Journal of Thoracic Oncology 11 (2016), 1482–1492.
-
(2016)
Journal of Thoracic Oncology
, vol.11
, pp. 1482-1492
-
-
Shintani, Y.1
Fujiwara, A.2
Kimura, T.3
Kawamura, T.4
Funaki, S.5
Minami, M.6
Okumura, M.7
-
151
-
-
84877855030
-
Hsp27 regulates epithelial mesenchymal transition, metastasis, and circulating tumor cells in prostate cancer
-
Shiota, M., Bishop, J.L., Nip, K.M., Zardan, A., Takeuchi, A., Cordonnier, T.,.. Zoubeidi, A., Hsp27 regulates epithelial mesenchymal transition, metastasis, and circulating tumor cells in prostate cancer. Cancer Research 73 (2013), 3109–3119.
-
(2013)
Cancer Research
, vol.73
, pp. 3109-3119
-
-
Shiota, M.1
Bishop, J.L.2
Nip, K.M.3
Zardan, A.4
Takeuchi, A.5
Cordonnier, T.6
Zoubeidi, A.7
-
152
-
-
34548496683
-
Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta
-
Shirakihara, T., Saitoh, M., Miyazono, K., Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta. Molecular Biology of the Cell 18 (2007), 3533–3544.
-
(2007)
Molecular Biology of the Cell
, vol.18
, pp. 3533-3544
-
-
Shirakihara, T.1
Saitoh, M.2
Miyazono, K.3
-
153
-
-
47949101915
-
IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis
-
Skov, L., Beurskens, F.J., Zachariae, C.O., Reitamo, S., Teeling, J., Satijn, D.,.. van de Winkel, J.G., IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis. Journal of Immunology 181 (2008), 669–679.
-
(2008)
Journal of Immunology
, vol.181
, pp. 669-679
-
-
Skov, L.1
Beurskens, F.J.2
Zachariae, C.O.3
Reitamo, S.4
Teeling, J.5
Satijn, D.6
van de Winkel, J.G.7
-
154
-
-
84904169349
-
EW-7197, a novel ALK-5 kinase inhibitor, potently inhibits breast to lung metastasis
-
Son, J.Y., Park, S.Y., Kim, S.J., Lee, S.J., Park, S.A., Kim, M.J.,.. Sheen, Y.Y., EW-7197, a novel ALK-5 kinase inhibitor, potently inhibits breast to lung metastasis. Molecular Cancer Therapeutics 13 (2014), 1704–1716.
-
(2014)
Molecular Cancer Therapeutics
, vol.13
, pp. 1704-1716
-
-
Son, J.Y.1
Park, S.Y.2
Kim, S.J.3
Lee, S.J.4
Park, S.A.5
Kim, M.J.6
Sheen, Y.Y.7
-
155
-
-
84934764818
-
A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcome
-
Soundararajan, R., Paranjape, A.N., Barsan, V., Chang, J.T., Mani, S.A., A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcome. Scientific Reports, 5, 2015, 11766.
-
(2015)
Scientific Reports
, vol.5
, pp. 11766
-
-
Soundararajan, R.1
Paranjape, A.N.2
Barsan, V.3
Chang, J.T.4
Mani, S.A.5
-
156
-
-
76649119826
-
Aurora-A gene is frequently amplified in basal-like breast cancer
-
Staff, S., Isola, J., Jumppanen, M., Tanner, M., Aurora-A gene is frequently amplified in basal-like breast cancer. Oncology Reports 23 (2010), 307–312.
-
(2010)
Oncology Reports
, vol.23
, pp. 307-312
-
-
Staff, S.1
Isola, J.2
Jumppanen, M.3
Tanner, M.4
-
157
-
-
69249221254
-
Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells
-
Sullivan, N.J., Sasser, A.K., Axel, A.E., Vesuna, F., Raman, V., Ramirez, N.,.. Hall, B.M., Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells. Oncogene 28 (2009), 2940–2947.
-
(2009)
Oncogene
, vol.28
, pp. 2940-2947
-
-
Sullivan, N.J.1
Sasser, A.K.2
Axel, A.E.3
Vesuna, F.4
Raman, V.5
Ramirez, N.6
Hall, B.M.7
-
158
-
-
84943244867
-
Targeting the WNT signaling pathway in cancer therapeutics
-
Tai, D., Wells, K., Arcaroli, J., Vanderbilt, C., Aisner, D.L., Messersmith, W.A., Lieu, C.H., Targeting the WNT signaling pathway in cancer therapeutics. The Oncologist 20 (2015), 1189–1198.
-
(2015)
The Oncologist
, vol.20
, pp. 1189-1198
-
-
Tai, D.1
Wells, K.2
Arcaroli, J.3
Vanderbilt, C.4
Aisner, D.L.5
Messersmith, W.A.6
Lieu, C.H.7
-
159
-
-
84908086125
-
Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients
-
Tan, T.Z., Miow, Q.H., Miki, Y., Noda, T., Mori, S., Huang, R.Y., Thiery, J.P., Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients. EMBO Molecular Medicine 6 (2014), 1279–1293.
-
(2014)
EMBO Molecular Medicine
, vol.6
, pp. 1279-1293
-
-
Tan, T.Z.1
Miow, Q.H.2
Miki, Y.3
Noda, T.4
Mori, S.5
Huang, R.Y.6
Thiery, J.P.7
-
160
-
-
85069157892
-
An epithelial marker promoter induction screen identifies histone deacetylase inhibitors to restore epithelial differentiation and abolishes anchorage independence growth in cancers
-
Tang, H.M., Kuay, K.T., Koh, P.F., Asad, M., Tan, T.Z., Chung, V.Y.,.. Huang, R.J., An epithelial marker promoter induction screen identifies histone deacetylase inhibitors to restore epithelial differentiation and abolishes anchorage independence growth in cancers. Cell Death Discovery, 2, 2016, 16041.
-
(2016)
Cell Death Discovery
, vol.2
, pp. 16041
-
-
Tang, H.M.1
Kuay, K.T.2
Koh, P.F.3
Asad, M.4
Tan, T.Z.5
Chung, V.Y.6
Huang, R.J.7
-
161
-
-
22244473343
-
The fallacy of epithelial mesenchymal transition in neoplasia
-
(discussion 6000-5991)
-
Tarin, D., Thompson, E.W., Newgreen, D.F., The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Research 65 (2005), 5996–6000 (discussion 6000-5991).
-
(2005)
Cancer Research
, vol.65
, pp. 5996-6000
-
-
Tarin, D.1
Thompson, E.W.2
Newgreen, D.F.3
-
162
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery, J.P., Acloque, H., Huang, R.Y., Nieto, M.A., Epithelial-mesenchymal transitions in development and disease. Cell 139 (2009), 871–890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
163
-
-
27144477683
-
Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition
-
Thomson, S., Buck, E., Petti, F., Griffin, G., Brown, E., Ramnarine, N.,.. Haley, J.D., Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition. Cancer Research 65 (2005), 9455–9462.
-
(2005)
Cancer Research
, vol.65
, pp. 9455-9462
-
-
Thomson, S.1
Buck, E.2
Petti, F.3
Griffin, G.4
Brown, E.5
Ramnarine, N.6
Haley, J.D.7
-
164
-
-
57049132745
-
Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy
-
Thomson, S., Petti, F., Sujka-Kwok, I., Epstein, D., Haley, J.D., Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy. Clinical & Experimental Metastasis 25 (2008), 843–854.
-
(2008)
Clinical & Experimental Metastasis
, vol.25
, pp. 843-854
-
-
Thomson, S.1
Petti, F.2
Sujka-Kwok, I.3
Epstein, D.4
Haley, J.D.5
-
165
-
-
33746034613
-
Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition
-
Thuault, S., Valcourt, U., Petersen, M., Manfioletti, G., Heldin, C.H., Moustakas, A., Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition. The Journal of Cell Biology 174 (2006), 175–183.
-
(2006)
The Journal of Cell Biology
, vol.174
, pp. 175-183
-
-
Thuault, S.1
Valcourt, U.2
Petersen, M.3
Manfioletti, G.4
Heldin, C.H.5
Moustakas, A.6
-
166
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian, S.L., Hodi, F.S., Brahmer, J.R., Gettinger, S.N., Smith, D.C., McDermott, D.F.,.. Sznol, M., Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. The New England Journal of Medicine 366 (2012), 2443–2454.
-
(2012)
The New England Journal of Medicine
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Sznol, M.7
-
167
-
-
84870845421
-
Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
-
Tsai, J.H., Donaher, J.L., Murphy, D.A., Chau, S., Yang, J., Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis. Cancer Cell 22 (2012), 725–736.
-
(2012)
Cancer Cell
, vol.22
, pp. 725-736
-
-
Tsai, J.H.1
Donaher, J.L.2
Murphy, D.A.3
Chau, S.4
Yang, J.5
-
168
-
-
84920956732
-
PD-1 blockade induces responses by inhibiting adaptive immune resistance
-
Tumeh, P.C., Harview, C.L., Yearley, J.H., Shintaku, I.P., Taylor, E.J., Robert, L.,.. Ribas, A., PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature 515 (2014), 568–571.
-
(2014)
Nature
, vol.515
, pp. 568-571
-
-
Tumeh, P.C.1
Harview, C.L.2
Yearley, J.H.3
Shintaku, I.P.4
Taylor, E.J.5
Robert, L.6
Ribas, A.7
-
169
-
-
84921273906
-
Monensin inhibits canonical Wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice
-
Tumova, L., Pombinho, A.R., Vojtechova, M., Stancikova, J., Gradl, D., Krausova, M.,.. Korinek, V., Monensin inhibits canonical Wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice. Molecular Cancer Therapeutics 13 (2014), 812–822.
-
(2014)
Molecular Cancer Therapeutics
, vol.13
, pp. 812-822
-
-
Tumova, L.1
Pombinho, A.R.2
Vojtechova, M.3
Stancikova, J.4
Gradl, D.5
Krausova, M.6
Korinek, V.7
-
170
-
-
0033997615
-
Tyrosine kinase SYK: Essential functions for immunoreceptor signalling
-
Turner, M., Schweighoffer, E., Colucci, F., Di Santo, J.P., Tybulewicz, V.L., Tyrosine kinase SYK: Essential functions for immunoreceptor signalling. Immunology Today 21 (2000), 148–154.
-
(2000)
Immunology Today
, vol.21
, pp. 148-154
-
-
Turner, M.1
Schweighoffer, E.2
Colucci, F.3
Di Santo, J.P.4
Tybulewicz, V.L.5
-
171
-
-
2442705493
-
Snail blocks the cell cycle and confers resistance to cell death
-
Vega, S., Morales, A.V., Ocana, O.H., Valdes, F., Fabregat, I., Nieto, M.A., Snail blocks the cell cycle and confers resistance to cell death. Genes & Development 18 (2004), 1131–1143.
-
(2004)
Genes & Development
, vol.18
, pp. 1131-1143
-
-
Vega, S.1
Morales, A.V.2
Ocana, O.H.3
Valdes, F.4
Fabregat, I.5
Nieto, M.A.6
-
172
-
-
84870745374
-
Epigenetic control of epithelial-to-mesenchymal transition and cancer metastasis
-
Wang, Y., Shang, Y., Epigenetic control of epithelial-to-mesenchymal transition and cancer metastasis. Experimental Cell Research 319 (2013), 160–169.
-
(2013)
Experimental Cell Research
, vol.319
, pp. 160-169
-
-
Wang, Y.1
Shang, Y.2
-
173
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
Willert, K., Brown, J.D., Danenberg, E., Duncan, A.W., Weissman, I.L., Reya, T.,.. Nusse, R., Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423 (2003), 448–452.
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
Reya, T.6
Nusse, R.7
-
174
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok, J.D., Kluger, H., Callahan, M.K., Postow, M.A., Rizvi, N.A., Lesokhin, A.M.,.. Sznol, M., Nivolumab plus ipilimumab in advanced melanoma. The New England Journal of Medicine 369 (2013), 122–133.
-
(2013)
The New England Journal of Medicine
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
Postow, M.A.4
Rizvi, N.A.5
Lesokhin, A.M.6
Sznol, M.7
-
175
-
-
84929012563
-
Classification of circulating tumor cells by epithelial-mesenchymal transition markers
-
Wu, S., Liu, S., Liu, Z., Huang, J., Pu, X., Li, J.,.. Xu, J., Classification of circulating tumor cells by epithelial-mesenchymal transition markers. PLoS One, 10, 2015, e0123976.
-
(2015)
PLoS One
, vol.10
-
-
Wu, S.1
Liu, S.2
Liu, Z.3
Huang, J.4
Pu, X.5
Li, J.6
Xu, J.7
-
176
-
-
85006197275
-
PI3K/Akt/mTOR signaling pathway in cancer stem cells: From basic research to clinical application
-
Xia, P., Xu, X.Y., PI3K/Akt/mTOR signaling pathway in cancer stem cells: From basic research to clinical application. American Journal of Cancer Research 5 (2015), 1602–1609.
-
(2015)
American Journal of Cancer Research
, vol.5
, pp. 1602-1609
-
-
Xia, P.1
Xu, X.Y.2
-
177
-
-
84055207487
-
IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway
-
Yadav, A., Kumar, B., Datta, J., Teknos, T.N., Kumar, P., IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway. Molecular Cancer Research 9 (2011), 1658–1667.
-
(2011)
Molecular Cancer Research
, vol.9
, pp. 1658-1667
-
-
Yadav, A.1
Kumar, B.2
Datta, J.3
Teknos, T.N.4
Kumar, P.5
-
178
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
Yang, J., Mani, S.A., Donaher, J.L., Ramaswamy, S., Itzykson, R.A., Come, C.,.. Weinberg, R.A., Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117 (2004), 927–939.
-
(2004)
Cell
, vol.117
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Weinberg, R.A.7
-
179
-
-
33751514601
-
A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells
-
Yook, J.I., Li, X.Y., Ota, I., Hu, C., Kim, H.S., Kim, N.H.,.. Weiss, S.J., A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells. Nature Cell Biology 8 (2006), 1398–1406.
-
(2006)
Nature Cell Biology
, vol.8
, pp. 1398-1406
-
-
Yook, J.I.1
Li, X.Y.2
Ota, I.3
Hu, C.4
Kim, H.S.5
Kim, N.H.6
Weiss, S.J.7
-
180
-
-
84881531214
-
Monensin, a polyether ionophore antibiotic, overcomes TRAIL resistance in glioma cells via endoplasmic reticulum stress, DR5 upregulation and c-FLIP downregulation
-
Yoon, M.J., Kang, Y.J., Kim, I.Y., Kim, E.H., Lee, J.A., Lim, J.H.,.. Choi, K.S., Monensin, a polyether ionophore antibiotic, overcomes TRAIL resistance in glioma cells via endoplasmic reticulum stress, DR5 upregulation and c-FLIP downregulation. Carcinogenesis 34 (2013), 1918–1928.
-
(2013)
Carcinogenesis
, vol.34
, pp. 1918-1928
-
-
Yoon, M.J.1
Kang, Y.J.2
Kim, I.Y.3
Kim, E.H.4
Lee, J.A.5
Lim, J.H.6
Choi, K.S.7
-
181
-
-
84873811988
-
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
-
Yu, M., Bardia, A., Wittner, B.S., Stott, S.L., Smas, M.E., Ting, D.T.,.. Maheswaran, S., Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science 339 (2013), 580–584.
-
(2013)
Science
, vol.339
, pp. 580-584
-
-
Yu, M.1
Bardia, A.2
Wittner, B.S.3
Stott, S.L.4
Smas, M.E.5
Ting, D.T.6
Maheswaran, S.7
-
182
-
-
84987623870
-
Wnt signaling in cancer
-
Zhan, T., Rindtorff, N., Boutros, M., Wnt signaling in cancer. Oncogene, 2016, 10.1038/onc.2016.1304.
-
(2016)
Oncogene
-
-
Zhan, T.1
Rindtorff, N.2
Boutros, M.3
-
183
-
-
58149213801
-
Non-Smad pathways in TGF-beta signaling
-
Zhang, Y.E., Non-Smad pathways in TGF-beta signaling. Cell Research 19 (2009), 128–139.
-
(2009)
Cell Research
, vol.19
, pp. 128-139
-
-
Zhang, Y.E.1
-
184
-
-
84958983172
-
Salinomycin suppresses TGF-beta1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells
-
Zhang, C., Lu, Y., Li, Q., Mao, J., Hou, Z., Yu, X.,.. Li, L., Salinomycin suppresses TGF-beta1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells. Chemico-Biological Interactions 248 (2016), 74–81.
-
(2016)
Chemico-Biological Interactions
, vol.248
, pp. 74-81
-
-
Zhang, C.1
Lu, Y.2
Li, Q.3
Mao, J.4
Hou, Z.5
Yu, X.6
Li, L.7
-
185
-
-
84923332481
-
ZEB1: at the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance
-
Zhang, P., Sun, Y., Ma, L., ZEB1: at the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance. Cell Cycle 14 (2015), 481–487.
-
(2015)
Cell Cycle
, vol.14
, pp. 481-487
-
-
Zhang, P.1
Sun, Y.2
Ma, L.3
-
186
-
-
84962407192
-
An iTEP-salinomycin nanoparticle that specifically and effectively inhibits metastases of 4T1 orthotopic breast tumors
-
Zhao, P., Xia, G., Dong, S., Jiang, Z.X., Chen, M., An iTEP-salinomycin nanoparticle that specifically and effectively inhibits metastases of 4T1 orthotopic breast tumors. Biomaterials 93 (2016), 1–9.
-
(2016)
Biomaterials
, vol.93
, pp. 1-9
-
-
Zhao, P.1
Xia, G.2
Dong, S.3
Jiang, Z.X.4
Chen, M.5
-
187
-
-
84948407218
-
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
-
Zheng, X., Carstens, J.L., Kim, J., Scheible, M., Kaye, J., Sugimoto, H.,.. Kalluri, R., Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature 527 (2015), 525–530.
-
(2015)
Nature
, vol.527
, pp. 525-530
-
-
Zheng, X.1
Carstens, J.L.2
Kim, J.3
Scheible, M.4
Kaye, J.5
Sugimoto, H.6
Kalluri, R.7
|