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Volumn 9, Issue 7, 2014, Pages

Wilms' tumor protein induces an epithelial-mesenchymal hybrid differentiation state in clear cell renal cell carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; VON HIPPEL LINDAU PROTEIN; WT1 PROTEIN; CADHERIN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; VHL PROTEIN, HUMAN; WNT PROTEIN;

EID: 84904257935     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102041     Document Type: Article
Times cited : (54)

References (37)
  • 2
    • 76349095132 scopus 로고    scopus 로고
    • Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
    • Semenza GL (2010) Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 29: 625-634.
    • (2010) Oncogene , vol.29 , pp. 625-634
    • Semenza, G.L.1
  • 3
    • 33749031535 scopus 로고    scopus 로고
    • The many facets of the Wilms' tumour gene, WT1
    • DOI 10.1093/hmg/ddl196
    • Hohenstein P, Hastie ND (2006) The many facets of the Wilms' tumour gene, WT1. Hum Mol Genet 15 Spec No 2: R196-201. (Pubitemid 44446794)
    • (2006) Human Molecular Genetics , vol.15 , Issue.SUPPL. 2
    • Hohenstein, P.1    Hastie, N.D.2
  • 4
    • 14744273156 scopus 로고    scopus 로고
    • A role for the Wilms' tumor protein WT1 in organ development
    • Scholz H, Kirschner KM (2005) A role for the Wilms' tumor protein WT1 in organ development. Physiology (Bethesda) 20: 54-59. (Pubitemid 40363371)
    • (2005) Physiology , Issue.1 , pp. 54-59
    • Scholz, H.1    Kirschner, K.M.2
  • 5
    • 73349108404 scopus 로고    scopus 로고
    • Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin
    • Martinez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, et al. (2010) Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat Genet 42: 89-93.
    • (2010) Nat Genet , vol.42 , pp. 89-93
    • Martinez-Estrada, O.M.1    Lettice, L.A.2    Essafi, A.3    Guadix, J.A.4    Slight, J.5
  • 6
    • 0035827923 scopus 로고    scopus 로고
    • WT1 proteins: Functions in growth and differentiation
    • DOI 10.1016/S0378-1119(01)00593-5, PII S0378111901005935
    • Scharnhorst V, van der Eb AJ, Jochemsen AG (2001) WT1 proteins: functions in growth and differentiation. Gene 273: 141-161. (Pubitemid 32786908)
    • (2001) Gene , vol.273 , Issue.2 , pp. 141-161
    • Scharnhorst, V.1    Van Der, E.A.J.2    Jochemsen, A.G.3
  • 7
    • 84861530654 scopus 로고    scopus 로고
    • Oxygen-Dependent Gene Expression in Development and Cancer: Lessons Learned from the Wilms' Tumor Gene, WT1
    • Scholz H, Kirschner KM (2011) Oxygen-Dependent Gene Expression in Development and Cancer: Lessons Learned from the Wilms' Tumor Gene, WT1. Front Mol Neurosci 4: 4.
    • (2011) Front Mol Neurosci , vol.4 , pp. 4
    • Scholz, H.1    Kirschner, K.M.2
  • 9
    • 0025325167 scopus 로고
    • Cadherins: A molecular family important in selective cell-cell adhesion
    • Takeichi M (1990) Cadherins: a molecular family important in selective cell-cell adhesion. Annual Reviews Biochemistry: 237-252.
    • (1990) Annual Reviews Biochemistry , pp. 237-252
    • Takeichi, M.1
  • 10
    • 33845414010 scopus 로고    scopus 로고
    • Cadherins in development: Cell adhesion, sorting, and tissue morphogenesis
    • DOI 10.1101/gad.1486806
    • Halbleib JM, Nelson WJ (2006) Cadherins in development: cell adhesion, sorting, and tissue morphogenesis. Genes Dev 20: 3199-3214. (Pubitemid 44904842)
    • (2006) Genes and Development , vol.20 , Issue.23 , pp. 3199-3214
    • Halbleib, J.M.1    Nelson, W.J.2
  • 11
    • 67651005404 scopus 로고    scopus 로고
    • EMT: When epithelial cells decide to become mesenchymal-like cells
    • Kalluri R (2009) EMT: when epithelial cells decide to become mesenchymal-like cells. J Clin Invest 119: 1417-1419.
    • (2009) J Clin Invest , vol.119 , pp. 1417-1419
    • Kalluri, R.1
  • 12
    • 77954505348 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in cancer onset and progression
    • discussion 1978-1969
    • Thiery JP (2009) [Epithelial-mesenchymal transitions in cancer onset and progression]. Bull Acad Natl Med 193: 1969-1978; discussion 1978-1969.
    • (2009) Bull Acad Natl Med , vol.193 , pp. 1969-1978
    • Thiery, J.P.1
  • 13
    • 84867578091 scopus 로고    scopus 로고
    • EMT-activating transcription factors in cancer: Beyond EMT and tumor invasiveness
    • Sanchez-Tillo E, Liu Y, de Barrios O, Siles L, Fanlo L, et al. (2012) EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness. Cell Mol Life Sci 69: 3429-3456.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 3429-3456
    • Sanchez-Tillo, E.1    Liu, Y.2    De Barrios, O.3    Siles, L.4    Fanlo, L.5
  • 14
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano A, Perez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, et al. (2000) The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2: 76-83.
    • (2000) Nat Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3    Locascio, A.4    Blanco, M.J.5
  • 15
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • DOI 10.1038/nrm1835, PII NRM1835
    • Thiery JP, Sleeman JP (2006) Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7: 131-142. (Pubitemid 43278296)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 17
    • 84861527239 scopus 로고    scopus 로고
    • To differentiate or not-routes towards metastasis
    • Brabletz T (2012) To differentiate or not-routes towards metastasis. Nat Rev Cancer 12: 425-436.
    • (2012) Nat Rev Cancer , vol.12 , pp. 425-436
    • Brabletz, T.1
  • 18
    • 33749024777 scopus 로고    scopus 로고
    • Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
    • DOI 10.1158/0008-5472.CAN-06-0410
    • Christiansen JJ, Rajasekaran AK (2006) Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res 66: 8319-8326. (Pubitemid 44449137)
    • (2006) Cancer Research , vol.66 , Issue.17 , pp. 8319-8326
    • Christiansen, J.J.1    Rajasekaran, A.K.2
  • 19
    • 84867115486 scopus 로고    scopus 로고
    • Microenvironmental regulation of epithelial-mesenchymal transitions in cancer
    • Gao D, Vahdat LT, Wong S, Chang JC, Mittal V (2012) Microenvironmental regulation of epithelial-mesenchymal transitions in cancer. Cancer Res 72: 4883-4889.
    • (2012) Cancer Res , vol.72 , pp. 4883-4889
    • Gao, D.1    Vahdat, L.T.2    Wong, S.3    Chang, J.C.4    Mittal, V.5
  • 22
    • 0036718539 scopus 로고    scopus 로고
    • Molecular basis of the VHL hereditary cancer syndrome
    • Kaelin WG Jr. (2002) Molecular basis of the VHL hereditary cancer syndrome. Nat Rev Cancer 2: 673-682.
    • (2002) Nat Rev Cancer , vol.2 , pp. 673-682
    • Kaelin Jr., W.G.1
  • 23
    • 0038265455 scopus 로고    scopus 로고
    • Oxygen-regulated expression of the Wilms' tumor suppressor Wt1 involves hypoxia-inducible factor-1 (HIF-1)
    • Wagner KD, Wagner N, Wellmann S, Schley G, Bondke A, et al. (2003) Oxygen-regulated expression of the Wilms' tumor suppressor Wt1 involves hypoxia-inducible factor-1 (HIF-1). FASEB J 17: 1364-1366.
    • (2003) FASEB J , vol.17 , pp. 1364-1366
    • Wagner, K.D.1    Wagner, N.2    Wellmann, S.3    Schley, G.4    Bondke, A.5
  • 26
    • 0033005665 scopus 로고    scopus 로고
    • YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis
    • Moore AW, McInnes L, Kreidberg J, Hastie ND, Schedl A (1999) YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis. Development 126: 1845-1857. (Pubitemid 29240319)
    • (1999) Development , vol.126 , Issue.9 , pp. 1845-1857
    • Moore, A.W.1    McInnes, L.2    Kreidberg, J.3    Hastie, N.D.4    Schedl, A.5
  • 27
    • 73349108404 scopus 로고    scopus 로고
    • Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin
    • Martinez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, et al. Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat Genet 42: 89-93.
    • Nat Genet , vol.42 , pp. 89-93
    • Martinez-Estrada, O.M.1    Lettice, L.A.2    Essafi, A.3    Guadix, J.A.4    Slight, J.5
  • 28
    • 84871974907 scopus 로고    scopus 로고
    • The Wilms' tumor gene (WT1) regulates E-cadherin expression and migration of prostate cancer cells
    • Brett A, Pandey S, Fraizer G (2013) The Wilms' tumor gene (WT1) regulates E-cadherin expression and migration of prostate cancer cells. Mol Cancer 12: 3.
    • (2013) Mol Cancer , vol.12 , pp. 3
    • Brett, A.1    Pandey, S.2    Fraizer, G.3
  • 29
    • 44449111555 scopus 로고    scopus 로고
    • Loss of Ecadherin promotes metastasis via multiple downstream transcriptional pathways
    • Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, et al. (2008) Loss of Ecadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res 68: 3645-3654.
    • (2008) Cancer Res , vol.68 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3    Yang, J.4    Lander, E.S.5
  • 31
    • 77953382455 scopus 로고    scopus 로고
    • Na,K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis
    • Rajasekaran SA, Huynh TP, Wolle DG, Espineda CE, Inge LJ, et al. (2010) Na,K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis. Mol Cancer Ther 9: 1515-1524.
    • (2010) Mol Cancer Ther , vol.9 , pp. 1515-1524
    • Rajasekaran, S.A.1    Huynh, T.P.2    Wolle, D.G.3    Espineda, C.E.4    Inge, L.J.5
  • 32
    • 59649129136 scopus 로고    scopus 로고
    • VHL loss of function and its impact on oncogenic signaling networks in clear cell renal cell carcinoma
    • Linehan WM, Rubin JS, Bottaro DP (2009) VHL loss of function and its impact on oncogenic signaling networks in clear cell renal cell carcinoma. Int J Biochem Cell Biol 41: 753-756.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 753-756
    • Linehan, W.M.1    Rubin, J.S.2    Bottaro, D.P.3
  • 33
    • 0029295649 scopus 로고
    • Expression of the Von Hippel-Lindau tumor suppressor gene, VHL, in human fetal kidney and during mouse embryogenesis
    • Kessler PM, Vasavada SP, Rackley RR, Stackhouse T, Duh FM, et al. (1995) Expression of the Von Hippel-Lindau tumor suppressor gene, VHL, in human fetal kidney and during mouse embryogenesis. Mol Med 1: 457-466.
    • (1995) Mol Med , vol.1 , pp. 457-466
    • Kessler, P.M.1    Vasavada, S.P.2    Rackley, R.R.3    Stackhouse, T.4    Duh, F.M.5
  • 34
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • Batlle E, Sancho E, Franci C, Dominguez D, Monfar M, et al. (2000) The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol 2: 84-89.
    • (2000) Nat Cell Biol , vol.2 , pp. 84-89
    • Batlle, E.1    Sancho, E.2    Franci, C.3    Dominguez, D.4    Monfar, M.5
  • 35
    • 6944248910 scopus 로고    scopus 로고
    • Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro
    • DOI 10.1593/neo.04241
    • Xie L, Law BK, Chytil AM, Brown KA, Aakre ME, et al. (2004) Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia 6: 603-610. (Pubitemid 39411098)
    • (2004) Neoplasia , vol.6 , Issue.5 , pp. 603-610
    • Xie, L.1    Law, B.K.2    Chytil, A.M.3    Brown, K.A.4    Aakre, M.E.5    Moses, H.L.6
  • 36
    • 33751038930 scopus 로고    scopus 로고
    • Different isoforms of the Wilms' tumour protein WT1 have distinct patterns of distribution and trafficking within the nucleus
    • DOI 10.1111/j.1365-2184.2006.00409.x
    • Dutton JR, Lahiri D, Ward A (2006) Different isoforms of the Wilms' tumour protein WT1 have distinct patterns of distribution and trafficking within the nucleus. Cell Prolif 39: 519-535. (Pubitemid 44760203)
    • (2006) Cell Proliferation , vol.39 , Issue.6 , pp. 519-535
    • Dutton, J.R.1    Lahiri, D.2    Ward, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.