IL-8 as antibody therapeutic target in inflammatory diseases: Reduction of clinical activity in palmoplantar pustulosis

Journal of Immunology

Volumn 181, Issue 1, 2008, Pages 669-679

  Skov, Lone ^a   Beurskens, Frank J ^b   Zachariae, Claus O C ^a   Reitamo, Sakari ^c   Teeling, Jessica ^b   Satijn, David ^b   Knudsen, Kim M ^e,f   Boot, Elmieke P J ^b   Hudson, Debra ^d   Baadsgaard, Ole ^e,f   Parren, Paul W H I ^b   Van De Winkel, Jan G J ^g  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b GENMAB   (Netherlands)

^c UNIVERSITY OF HELSINKI   (Finland)

^d Medarex   (United States)

^e Genmab   (Denmark)

^f UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^g UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN MONOCLONAL ANTIBODY; HUMAN MONOCLONAL ANTIBODY 10F8; INTERLEUKIN 8; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; EPITOPE; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; HUMAN; HUMAN TISSUE; IMMUNOMODULATION; IMMUNOTHERAPY; LEUKOCYTE ACTIVATION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUSTULOSIS PALMOPLANTARIS; AMINO ACID SEQUENCE; ANIMAL; BLOOD; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INFLAMMATION; MOLECULAR GENETICS; NEUTROPHIL; PATHOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; PSORIASIS; TIME; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CELLS, CULTURED; EPITOPES; HUMANS; IMMUNE TOLERANCE; IMMUNOTHERAPY; INFLAMMATION; INTERLEUKIN-8; MICE; MICE, TRANSGENIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEUTROPHILS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PSORIASIS; TIME FACTORS;

EID: 47949101915     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.1.669     Document Type: Article

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