Salinomycin inhibits wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 32, 2011, Pages 13253-13257

  Lu, Desheng ^a   Choi, Michael Y ^a   Yu, Jian ^a   Castro, Januario E ^a   Kipps, Thomas J ^a   Carson, Dennis A ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

B cell neoplasm; Canonical Wnt antagonist; LRP6 stability

Indexed keywords

CYCLIN D1; FIBRONECTIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; LYMPHOID ENHANCER FACTOR 1; NIGERICIN; SALINOMYCIN; WNT PROTEIN;

APOPTOSIS; ARTICLE; CELL STRAIN HEK293; CELL SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; INTRACELLULAR SIGNALING; LEUKEMIA CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION;

APOPTOSIS; BETA CATENIN; CALCIUM; DOWN-REGULATION; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, NEOPLASM; HEK293 CELLS; HUMANS; LDL-RECEPTOR RELATED PROTEINS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; NIGERICIN; PHOSPHORYLATION; PYRANS; SIGNAL TRANSDUCTION; THAPSIGARGIN; WNT PROTEINS;

EID: 80052012674     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1110431108     Document Type: Article

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