Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

Nature

Volumn 527, Issue 7579, 2015, Pages 525-530

  Zheng, Xiaofeng ^a   Carstens, Julienne L ^a   Kim, Jiha ^a   Scheible, Matthew ^a   Kaye, Judith ^a   Sugimoto, Hikaru ^a   Wu, Chia Chin ^a   Lebleu, Valerie S ^a   Kalluri, Raghu ^a,b,c  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c Rice University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERLOTINIB; GEMCITABINE; NUCLEOSIDE TRANSPORTER; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; DEOXYCYTIDINE; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

CANCER; CHEMOTHERAPY; GENE EXPRESSION; GENETIC ENGINEERING; HOMEOSTASIS; MOLECULAR ANALYSIS; PHENOTYPE; RODENT; SNAIL; TUMOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CELL PROLIFERATION; CONTROLLED STUDY; DRUG RESISTANCE; DRUG SENSITIVITY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE DELETION; LIVER METASTASIS; LUNG METASTASIS; MALE; METASTASIS; MOUSE; NONHUMAN; OVERALL SURVIVAL; PANCREAS ADENOCARCINOMA; PRIMARY TUMOR; PRIORITY JOURNAL; SPLEEN METASTASIS; TUMOR INVASION; ADENOCARCINOMA; ANALOGS AND DERIVATIVES; ANIMAL; CARCINOMA, PANCREATIC DUCTAL; DEFICIENCY; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; PANCREATIC NEOPLASMS; PATHOLOGY; SURVIVAL;

GASTROPODA; MUS;

ADENOCARCINOMA; ANIMALS; CARCINOMA, PANCREATIC DUCTAL; CELL PROLIFERATION; DEOXYCYTIDINE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; MALE; MICE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NUCLEOSIDE TRANSPORT PROTEINS; PANCREATIC NEOPLASMS; SURVIVAL ANALYSIS; TRANSCRIPTION FACTORS; TWIST TRANSCRIPTION FACTOR;

EID: 84948407218     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16064     Document Type: Article

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