Monensin inhibits canonical Wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice

Molecular Cancer Therapeutics

Volumn 13, Issue 4, 2014, Pages 812-822

  Tumova, Lucie ^a   Pombinho, Antonio R ^a   Vojtechova, Martina ^a   Stancikova, Jitka ^a   Gradl, Dietmar ^d   Krausova, Michaela ^a   Sloncova, Eva ^a   Horazna, Monika ^a   Kriz, Vitezslav ^a   Machonova, Olga ^a   Jindrich, Jindrich ^a,b   Zdrahal, Zbynek ^c   Bartunek, Petr ^a   Korinek, Vladimir ^a  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c MASARYK UNIVERSITY   (Czech Republic)

^d UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; IONOPHORE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MONENSIN; ANTINEOPLASTIC ANTIBIOTIC;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL REGENERATION; CELL STRAIN HEK293; COLORECTAL CARCINOMA; CONTROLLED STUDY; GENE TARGETING; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPORTER GENE; TUMOR GROWTH; TUMOR VOLUME; WNT SIGNALING PATHWAY; ZEBRA FISH; ANIMAL; COLORECTAL NEOPLASMS; DRUG EFFECTS; DRUG SCREENING; EXPERIMENTAL NEOPLASM; GENE EXPRESSION REGULATION; HEK293 CELL LINE; HUMAN; METABOLISM; PATHOLOGY; TUMOR CELL LINE; XENOPUS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BETA CATENIN; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; MICE; MONENSIN; NEOPLASMS, EXPERIMENTAL; WNT SIGNALING PATHWAY; XENOGRAFT MODEL ANTITUMOR ASSAYS; XENOPUS; ZEBRAFISH;

EID: 84921273906     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-13-0625     Document Type: Article

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