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Volumn 21, Issue 3, 2000, Pages 148-154

Tyrosine kinase SYK: Essential functions for immunoreceptor signalling

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; FC RECEPTOR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR;

EID: 0033997615     PISSN: 01675699     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5699(99)01574-1     Document Type: Review
Times cited : (355)

References (54)
  • 1
    • 0028977990 scopus 로고
    • Association of p72 Syk with the SRC homology-2 (SH2) domains of PLC-γ1 in B lymphocytes
    • Sillman A.L., Monroe J.G. Association of p72 Syk with the SRC homology-2 (SH2) domains of PLC-γ1 in B lymphocytes. J. Biol. Chem. 270:1995;11806-11811.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11806-11811
    • Sillman, A.L.1    Monroe, J.G.2
  • 2
    • 0031552069 scopus 로고    scopus 로고
    • Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk
    • Furlong M.T.et al. Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk. Biochim. Biophys. Acta. 1355:1997;177-190.
    • (1997) Biochim. Biophys. Acta , vol.1355 , pp. 177-190
    • Furlong, M.T.1
  • 3
    • 0029670081 scopus 로고    scopus 로고
    • Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk
    • Law C.L.et al. Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk. Mol. Cell. Biol. 16:1996;1305-1315.
    • (1996) Mol. Cell. Biol , vol.16 , pp. 1305-1315
    • Law, C.L.1
  • 4
    • 0032546910 scopus 로고    scopus 로고
    • T cell activation induced by novel gain-of-function mutants of Syk and ZAP-70
    • Zeitlmann L.et al. T cell activation induced by novel gain-of-function mutants of Syk and ZAP-70. J. Biol. Chem. 273:1998;15445-15452.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15445-15452
    • Zeitlmann, L.1
  • 5
    • 0032079343 scopus 로고    scopus 로고
    • The unique insert in the linker domain of Syk is necessary for its function in immunoreceptor signalling
    • Latour S.et al. The unique insert in the linker domain of Syk is necessary for its function in immunoreceptor signalling. EMBO J. 17:1998;2584-2595.
    • (1998) EMBO J , vol.17 , pp. 2584-2595
    • Latour, S.1
  • 6
    • 0031788487 scopus 로고    scopus 로고
    • The Syk family of protein tyrosine kinases in T-cell activation and development
    • Chu D.H.et al. The Syk family of protein tyrosine kinases in T-cell activation and development. Immunol. Rev. 165:1998;167-180.
    • (1998) Immunol. Rev , vol.165 , pp. 167-180
    • Chu, D.H.1
  • 7
    • 0027185152 scopus 로고
    • T cell activation by clustered tyrosine kinases
    • Kolanus W.et al. T cell activation by clustered tyrosine kinases. Cell. 74:1993;171-183.
    • (1993) Cell , vol.74 , pp. 171-183
    • Kolanus, W.1
  • 8
    • 0028209548 scopus 로고
    • Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases
    • Iwashima M.et al. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science. 263:1994;1136-1139.
    • (1994) Science , vol.263 , pp. 1136-1139
    • Iwashima, M.1
  • 9
    • 0029952988 scopus 로고    scopus 로고
    • The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling
    • Chu D.et al. The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling. EMBO J. 15:1996;6251-6261.
    • (1996) EMBO J , vol.15 , pp. 6251-6261
    • Chu, D.1
  • 10
    • 0026483786 scopus 로고
    • ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
    • Chan A.C.et al. ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain. Cell. 71:1992;649-662.
    • (1992) Cell , vol.71 , pp. 649-662
    • Chan, A.C.1
  • 11
    • 0028355565 scopus 로고
    • Syk activation by the SRC-family tyrosine kinase in the B cell receptor signaling
    • Kurosaki T.et al. Syk activation by the SRC-family tyrosine kinase in the B cell receptor signaling. J. Exp. Med. 179:1994;1725-1729.
    • (1994) J. Exp. Med , vol.179 , pp. 1725-1729
    • Kurosaki, T.1
  • 12
    • 0028169299 scopus 로고
    • Activation of p56lck by p72syk through physical association and N-terminal tyrosine phosphorylation
    • Couture C.et al. Activation of p56lck by p72syk through physical association and N-terminal tyrosine phosphorylation. Mol. Cell. Biol. 14:1994;5249-5258.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5249-5258
    • Couture, C.1
  • 13
    • 0031568534 scopus 로고    scopus 로고
    • Protein tyrosine kinases Syk and ZAP-70 display distinct requirements for SRC family kinases in immune response receptor signal transduction
    • Zoller K.et al. Protein tyrosine kinases Syk and ZAP-70 display distinct requirements for SRC family kinases in immune response receptor signal transduction. J. Immunol. 158:1997;1650-1659.
    • (1997) J. Immunol. , vol.158 , pp. 1650-1659
    • Zoller, K.1
  • 14
    • 0029068171 scopus 로고
    • Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation
    • Rowley R.B.et al. Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation. J. Biol. Chem. 270:1995;11590-11594.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11590-11594
    • Rowley, R.B.1
  • 15
    • 0029864882 scopus 로고    scopus 로고
    • Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides
    • Kimura T.et al. Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides. Mol. Cell. Biol. 16:1996;1471-1478.
    • (1996) Mol. Cell. Biol , vol.16 , pp. 1471-1478
    • Kimura, T.1
  • 16
    • 0028793187 scopus 로고
    • Phosphorylated immunoreceptor signaling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases
    • Johnson S.A.et al. Phosphorylated immunoreceptor signaling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases. J. Immunol. 155:1995;4596-4603.
    • (1995) J. Immunol. , vol.155 , pp. 4596-4603
    • Johnson, S.A.1
  • 17
    • 0028216232 scopus 로고
    • Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling
    • Chan A.C.et al. Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. J. Immunol. 152:1994;4758-4766.
    • (1994) J. Immunol. , vol.152 , pp. 4758-4766
    • Chan, A.C.1
  • 18
    • 0029133646 scopus 로고
    • Essential role for ZAP-70 in both positive and negative selection of thymocytes
    • Negishi I.et al. Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature. 376:1995;435-438.
    • (1995) Nature , vol.376 , pp. 435-438
    • Negishi, I.1
  • 19
    • 0030802186 scopus 로고    scopus 로고
    • A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development
    • Wiest D.et al. A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development. Immunity. 6:1997;663-671.
    • (1997) Immunity , vol.6 , pp. 663-671
    • Wiest, D.1
  • 20
    • 0030756320 scopus 로고    scopus 로고
    • -/- mice by the Syk protein tyrosine kinase
    • -/- mice by the Syk protein tyrosine kinase. Immunity. 7:1997;369-377.
    • (1997) Immunity , vol.7 , pp. 369-377
    • Gong, Q.1
  • 21
    • 0033197970 scopus 로고    scopus 로고
    • Pre-T cell receptor signals are responsible for the down regulation of Syk protein Tyrosine Kinase expression
    • Chu D.H.et al. Pre-T cell receptor signals are responsible for the down regulation of Syk protein Tyrosine Kinase expression. J. Immunol. 163:1999;2610-2620.
    • (1999) J. Immunol , vol.163 , pp. 2610-2620
    • Chu, D.H.1
  • 22
    • 0030886836 scopus 로고    scopus 로고
    • The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling
    • Cheng A.M.et al. The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling. Proc. Natl. Acad. Sci. U. S. A. 94:1997;9797-9801.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 9797-9801
    • Cheng, A.M.1
  • 23
    • 0028979462 scopus 로고
    • Differential contribution of the FcR gamma chain to the surface expression of the T cell receptor among T cells localized in epithelia: Analysis of FcR gamma-deficient mice
    • Park S.Y.et al. Differential contribution of the FcR gamma chain to the surface expression of the T cell receptor among T cells localized in epithelia: analysis of FcR gamma-deficient mice. Eur. J. Immunol. 25:1995;2107-2110.
    • (1995) Eur. J. Immunol , vol.25 , pp. 2107-2110
    • Park, S.Y.1
  • 24
    • 0028889302 scopus 로고
    • Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
    • Turner M.et al. Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Nature. 378:1995;298-302.
    • (1995) Nature , vol.378 , pp. 298-302
    • Turner, M.1
  • 25
    • 9544246859 scopus 로고    scopus 로고
    • Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase
    • Mallick-Wood C.A.et al. Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase. Proc. Natl. Acad. Sci. U. S. A. 93:1996;9704-9709.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 9704-9709
    • Mallick-Wood, C.A.1
  • 26
    • 0033104742 scopus 로고    scopus 로고
    • Dissecting NK cell development using a novel alymphoid mouse model: Investigating the role of the c-abl proto-oncogene in murine NK cell differentiation
    • Colucci F.et al. Dissecting NK cell development using a novel alymphoid mouse model: investigating the role of the c-abl proto-oncogene in murine NK cell differentiation. J. Immunol. 162:1999;2761-2765.
    • (1999) J. Immunol , vol.162 , pp. 2761-2765
    • Colucci, F.1
  • 27
    • 0032211059 scopus 로고    scopus 로고
    • Differential requirements for ZAP-70 in TCR signaling and T cell development
    • Kadlecek T.A.et al. Differential requirements for ZAP-70 in TCR signaling and T cell development. J. Immunol. 161:1998;4688-4694.
    • (1998) J. Immunol , vol.161 , pp. 4688-4694
    • Kadlecek, T.A.1
  • 28
    • 0030848994 scopus 로고    scopus 로고
    • Signal transduction during natural killer cell activation: Inside the mind of a killer
    • Leibson P. Signal transduction during natural killer cell activation: inside the mind of a killer. Immunity. 6:1997;655-661.
    • (1997) Immunity , vol.6 , pp. 655-661
    • Leibson, P.1
  • 29
    • 0033566806 scopus 로고    scopus 로고
    • Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation
    • Colucci F.et al. Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation. J. Immunol. 163:1999;1769-1774.
    • (1999) J. Immunol , vol.163 , pp. 1769-1774
    • Colucci, F.1
  • 30
    • 0031438155 scopus 로고    scopus 로고
    • Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity
    • Brumbaugh K.et al. Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity. J. Exp. Med. 186:1997;1965-1974.
    • (1997) J. Exp. Med. , vol.186 , pp. 1965-1974
    • Brumbaugh, K.1
  • 31
    • 0028042424 scopus 로고
    • FcR gamma chain deletion results in pleiotrophic effector cell defects
    • Takai T.et al. FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell. 76:1994;519-529.
    • (1994) Cell , vol.76 , pp. 519-529
    • Takai, T.1
  • 32
    • 0027432384 scopus 로고
    • -/- mutant mice and identification of a novel T cell population in the intestine
    • -/- mutant mice and identification of a novel T cell population in the intestine. EMBO J. 12:1993;4863-4875.
    • (1993) EMBO J. , vol.12 , pp. 4863-4875
    • Liu, C.P.1
  • 33
    • 0032510146 scopus 로고    scopus 로고
    • Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
    • Lanier L.et al. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature. 391:1998;703-707.
    • (1998) Nature , vol.391 , pp. 703-707
    • Lanier, L.1
  • 34
    • 0032113141 scopus 로고    scopus 로고
    • Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors
    • Smith K.M.et al. Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors. J. Immunol. 161:1998;7-10.
    • (1998) J. Immunol , vol.161 , pp. 7-10
    • Smith, K.M.1
  • 35
    • 0031283018 scopus 로고    scopus 로고
    • + T cells
    • + T cells. J. Exp. Med. 186:1997;1957-1963.
    • (1997) J. Exp. Med. , vol.186 , pp. 1957-1963
    • Arase, N.1
  • 36
    • 0028783322 scopus 로고
    • Syk tyrosine kinase required for mouse viability and B-cell development
    • Cheng A.M.et al. Syk tyrosine kinase required for mouse viability and B-cell development. Nature. 378:1995;303-306.
    • (1995) Nature , vol.378 , pp. 303-306
    • Cheng, A.M.1
  • 37
    • 0031976640 scopus 로고    scopus 로고
    • B-cell receptor regulation of peripheral B cells
    • MacLennan I. B-cell receptor regulation of peripheral B cells. Curr. Opin. Immunol. 10:1998;220-225.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 220-225
    • MacLennan, I.1
  • 38
    • 0031456145 scopus 로고    scopus 로고
    • Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating pool
    • Turner M.et al. Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating pool. J. Exp. Med. 186:1997;2013-2021.
    • (1997) J. Exp. Med , vol.186 , pp. 2013-2021
    • Turner, M.1
  • 39
    • 0030604541 scopus 로고    scopus 로고
    • The Fc(epsilon)RIbeta subunit functions as an amplifier of Fc(epsilon)RIgamma-mediated cell activation signals
    • Lin S.et al. The Fc(epsilon)RIbeta subunit functions as an amplifier of Fc(epsilon)RIgamma-mediated cell activation signals. Cell. 85:1996;985-995.
    • (1996) Cell , vol.85 , pp. 985-995
    • Lin, S.1
  • 40
    • 0029058030 scopus 로고
    • Activation of the high-affinity immunoglobulin E receptor Fc epsilon RI in RBL-2H3 cells is inhibited by Syk SH2 domains
    • Taylor J.A.et al. Activation of the high-affinity immunoglobulin E receptor Fc epsilon RI in RBL-2H3 cells is inhibited by Syk SH2 domains. Mol. Cell. Biol. 15:1995;4149-4157.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 4149-4157
    • Taylor, J.A.1
  • 41
    • 0030018183 scopus 로고    scopus 로고
    • Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells
    • Zhang J.et al. Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells. J. Exp. Med. 184:1996;71-79.
    • (1996) J. Exp. Med. , vol.184 , pp. 71-79
    • Zhang, J.1
  • 42
    • 0030472724 scopus 로고    scopus 로고
    • Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells
    • Costello P.S.et al. Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells. Oncogene. 13:1996;2595-2605.
    • (1996) Oncogene , vol.13 , pp. 2595-2605
    • Costello, P.S.1
  • 43
    • 0028558502 scopus 로고
    • Initial events in Fc epsilon RI signal transduction
    • Scharenberg A.M., Kinet J.P. Initial events in Fc epsilon RI signal transduction. J. Allergy. Clin. Immunol. 94:1994;1142-1146.
    • (1994) J. Allergy. Clin. Immunol , vol.94 , pp. 1142-1146
    • Scharenberg, A.M.1    Kinet, J.P.2
  • 44
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss A., Littman D.R. Signal transduction by lymphocyte antigen receptors. Cell. 76:1994;263-274.
    • (1994) Cell , vol.76 , pp. 263-274
    • Weiss, A.1    Littman, D.R.2
  • 45
    • 0028892541 scopus 로고
    • The molecular dissection of Fc gamma receptor mediated phagocytosis
    • Indik Z.et al. The molecular dissection of Fc gamma receptor mediated phagocytosis. Blood. 86:1995;4389-4399.
    • (1995) Blood , vol.86 , pp. 4389-4399
    • Indik, Z.1
  • 46
    • 0030049906 scopus 로고    scopus 로고
    • Clustered syk tyrosine kinase domains trigger phagocytosis
    • Greenberg S.et al. Clustered syk tyrosine kinase domains trigger phagocytosis. Proc. Natl. Acad. Sci. U. S. A. 93:1996;1103-1107.
    • (1996) Proc. Natl. Acad. Sci. U. S. a , vol.93 , pp. 1103-1107
    • Greenberg, S.1
  • 47
    • 0031807018 scopus 로고    scopus 로고
    • The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils
    • Kiefer F.et al. The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils. Mol. Cell. Biol. 18:1998;4209-4220.
    • (1998) Mol. Cell. Biol , vol.18 , pp. 4209-4220
    • Kiefer, F.1
  • 48
    • 0030829551 scopus 로고    scopus 로고
    • A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages
    • Crowley M.T.et al. A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages. J. Exp. Med. 186:1997;1027-1039.
    • (1997) J. Exp. Med. , vol.186 , pp. 1027-1039
    • Crowley, M.T.1
  • 49
    • 0030917981 scopus 로고    scopus 로고
    • The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen
    • Poole A.et al. The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. EMBO J. 16:1997;2333-2341.
    • (1997) EMBO J. , vol.16 , pp. 2333-2341
    • Poole, A.1
  • 50
    • 0032102098 scopus 로고    scopus 로고
    • Collagen receptor signalling in platelets: Extending the role of the ITAM
    • Watson S.P., Gibbins J. Collagen receptor signalling in platelets: extending the role of the ITAM. Immunol Today. 19:1998;260-264.
    • (1998) Immunol Today , vol.19 , pp. 260-264
    • Watson, S.P.1    Gibbins, J.2
  • 51
    • 0033561189 scopus 로고    scopus 로고
    • Genetic and pharmacological analyses of Syk function in alphaIIbbeta3 signaling in platelets
    • Law D.A.et al. Genetic and pharmacological analyses of Syk function in alphaIIbbeta3 signaling in platelets. Blood. 93:1999;2645-2652.
    • (1999) Blood , vol.93 , pp. 2645-2652
    • Law, D.A.1
  • 52
    • 0032563256 scopus 로고    scopus 로고
    • Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76
    • Pivniouk V.et al. Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell. 94:1998;229-238.
    • (1998) Cell , vol.94 , pp. 229-238
    • Pivniouk, V.1
  • 53
    • 0345654297 scopus 로고    scopus 로고
    • Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice
    • Clements J.L.et al. Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice. J. Clin. Invest. 103:1999;19-25.
    • (1999) J. Clin. Invest. , vol.103 , pp. 19-25
    • Clements, J.L.1
  • 54
    • 0030968306 scopus 로고    scopus 로고
    • Syk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130
    • Keshvara L.M.et al. Syk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130. J. Biol. Chem. 272:1997;10377-10381.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10377-10381
    • Keshvara, L.M.1


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