-
1
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 2001; 414: 105-11.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
2
-
-
84871335417
-
Stem cell niche in tissue homeostasis, aging and cancer
-
Singh SR. Stem cell niche in tissue homeostasis, aging and cancer. Curr Med Chem 2012; 19: 5965-74.
-
(2012)
Curr Med Chem
, vol.19
, pp. 5965-5974
-
-
Singh, S.R.1
-
3
-
-
82355186665
-
"Wnt/Β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming
-
Miki T, Yasuda SY, Kahn M. "Wnt/Β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming. Stem Cell Rev 2011; 7: 836-46.
-
(2011)
Stem Cell Rev
, vol.7
, pp. 836-846
-
-
Miki, T.1
Yasuda, S.Y.2
Kahn, M.3
-
4
-
-
77953715690
-
Targeting Wnt signaling: can we safely eradicate cancer stem cells?
-
Takahashi-Yanaga F, Kahn M. Targeting Wnt signaling: can we safely eradicate cancer stem cells? Clin Cancer Res 2010; 16: 3153-62.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3153-3162
-
-
Takahashi-Yanaga, F.1
Kahn, M.2
-
5
-
-
77953693899
-
Targeting hedgehog - a cancer stem cell pathway
-
Merchant AA, Matsui W. Targeting hedgehog - a cancer stem cell pathway. Clin Cancer Res 2010; 16: 3130-40.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3130-3140
-
-
Merchant, A.A.1
Matsui, W.2
-
6
-
-
77956331142
-
Notch signaling in the regulation of stem cell self-renewal and differentiation
-
Liu J, Sato C, Cerletti M, Wagers A. Notch signaling in the regulation of stem cell self-renewal and differentiation. Curr Top Dev Biol 2010; 92: 367-409.
-
(2010)
Curr Top Dev Biol
, vol.92
, pp. 367-409
-
-
Liu, J.1
Sato, C.2
Cerletti, M.3
Wagers, A.4
-
7
-
-
84918732190
-
Ueber Entzuendung und Eiterung [in German]
-
Cohnheim J. Ueber Entzuendung und Eiterung [in German]. Path Anat Physiol Klin Med 1867; 40: 1-79.
-
(1867)
Path Anat Physiol Klin Med
, vol.40
, pp. 1-79
-
-
Cohnheim, J.1
-
8
-
-
52549087785
-
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
-
Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008; 8: 755-68.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
11
-
-
79952370202
-
The cancer stem cell: premises, promises and challenges
-
Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med 2011; 17: 313-9.
-
(2011)
Nat Med
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
12
-
-
77956619560
-
Stem cells and cancer - the promise and puzzles
-
Visvader JE, Lindeman GJ. Stem cells and cancer - the promise and puzzles. Mol Oncol 2010; 4: 369-72.
-
(2010)
Mol Oncol
, vol.4
, pp. 369-372
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
13
-
-
34547113747
-
Tumor growth need not be driven by rare cancer stem cells
-
Kelly PN, Dakic A, Adams JM, Nutt SL, Strasser A. Tumor growth need not be driven by rare cancer stem cells. Science 2007; 317: 337.
-
(2007)
Science
, vol.317
, pp. 337
-
-
Kelly, P.N.1
Dakic, A.2
Adams, J.M.3
Nutt, S.L.4
Strasser, A.5
-
14
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3: 730-7.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
15
-
-
10944235028
-
Chronic versus acute myelogenous leukemia: a question of self-renewal
-
Jamieson CH, Weissman IL, Passegué E. Chronic versus acute myelogenous leukemia: a question of self-renewal. Cancer Cell 2004; 6: 531-3.
-
(2004)
Cancer Cell
, vol.6
, pp. 531-533
-
-
Jamieson, C.H.1
Weissman, I.L.2
Passegué, E.3
-
16
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID et al. Identification of human brain tumour initiating cells. Nature 2004; 432: 396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
17
-
-
27144557960
-
A tumorigenic subpopulation with stem cell properties in melanomas
-
Fang D, Nguyen TK, Leishear K et al. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res 2005; 65: 9328-37.
-
(2005)
Cancer Res
, vol.65
, pp. 9328-9337
-
-
Fang, D.1
Nguyen, T.K.2
Leishear, K.3
-
18
-
-
3042525924
-
Breast cancer, stem/progenitor cells and the estrogen receptor
-
Dontu G, El-Ashry D, Wicha MS. Breast cancer, stem/progenitor cells and the estrogen receptor. Trends Endocrinol Metab 2004; 15: 193-7.
-
(2004)
Trends Endocrinol Metab
, vol.15
, pp. 193-197
-
-
Dontu, G.1
El-Ashry, D.2
Wicha, M.S.3
-
19
-
-
34249980343
-
Identification and characterization of tumorigenic liver cancer stem/progenitor cells
-
Ma S, Chan KW, Hu L et al. Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology 2007; 132: 2542-56.
-
(2007)
Gastroenterology
, vol.132
, pp. 2542-2556
-
-
Ma, S.1
Chan, K.W.2
Hu, L.3
-
20
-
-
33847052127
-
Identification of Pancreatic Cancer Stem Cells
-
Li C, Heidt DG, Dalerba P et al. Identification of Pancreatic Cancer Stem Cells. Cancer Res 2007; 67: 1030-7.
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
-
21
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007; 445: 106-10.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
22
-
-
79551634544
-
The gamma catenin/CBP complex maintains survivin transcription in β-catenin deficient/depleted cancer cells
-
Kim YM, Ma H, Oehler V et al. The gamma catenin/CBP complex maintains survivin transcription in β-catenin deficient/depleted cancer cells. Curr Cancer Drug Targets 2011; 11: 213-25.
-
(2011)
Curr Cancer Drug Targets
, vol.11
, pp. 213-225
-
-
Kim, Y.M.1
Ma, H.2
Oehler, V.3
-
23
-
-
44449111555
-
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
-
Onder TT, Gupta PB, Mani SA et al. Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res 2008; 68: 3645-54.
-
(2008)
Cancer Res
, vol.68
, pp. 3645-3654
-
-
Onder, T.T.1
Gupta, P.B.2
Mani, S.A.3
-
24
-
-
0031741386
-
Tissue-specific expression of beta-catenin in normal mesenchyme and uveal melanomas and its effect on invasiveness
-
Kim K, Daniels KJ, Ha ED. Tissue-specific expression of beta-catenin in normal mesenchyme and uveal melanomas and its effect on invasiveness. Exp Cell Res 1998; 245: 79-90.
-
(1998)
Exp Cell Res
, vol.245
, pp. 79-90
-
-
Kim, K.1
Daniels, K.J.2
Ha, E.D.3
-
25
-
-
80054686286
-
Tumor metastasis: molecular insights and evolving paradigms
-
Valastyan S, Weinberg RA. Tumor metastasis: molecular insights and evolving paradigms. Cell 2011; 147: 275-92.
-
(2011)
Cell
, vol.147
, pp. 275-292
-
-
Valastyan, S.1
Weinberg, R.A.2
-
26
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-15.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
-
27
-
-
80052071814
-
β-Catenin is required for Ron receptor-induced mammary tumorigenesis
-
Wagh PK, Gary JK, Zinser GM et al. β-Catenin is required for Ron receptor-induced mammary tumorigenesis. Oncogene 2011; 30: 3694-704.
-
(2011)
Oncogene
, vol.30
, pp. 3694-3704
-
-
Wagh, P.K.1
Gary, J.K.2
Zinser, G.M.3
-
28
-
-
33644532202
-
SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling
-
Coluccia AM, Benati D, Dekhil H et al. SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling. Cancer Res 2006; 66: 2279-86.
-
(2006)
Cancer Res
, vol.66
, pp. 2279-2286
-
-
Coluccia, A.M.1
Benati, D.2
Dekhil, H.3
-
29
-
-
32444440622
-
Bcr interferes with beta-catenin-Tcf1 interaction
-
Ress A, Moelling K. Bcr interferes with beta-catenin-Tcf1 interaction. FEBS Lett 2006; 580: 1227-30.
-
(2006)
FEBS Lett
, vol.580
, pp. 1227-1230
-
-
Ress, A.1
Moelling, K.2
-
30
-
-
77957584397
-
O2 regulates stem cells through Wnt/β-catenin signalling
-
Mazumdar J, Obrien WT, Johnson RS et al. O2 regulates stem cells through Wnt/β-catenin signalling. Nat Cell Biol 2010; 12: 1007-13.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 1007-1013
-
-
Mazumdar, J.1
Obrien, W.T.2
Johnson, R.S.3
-
31
-
-
84901285520
-
Hypoxia selects for a quiescent, CML stem/leukemia initiating-like population dependent on CBP/catenin transcription
-
Kida A, Kahn M. Hypoxia selects for a quiescent, CML stem/leukemia initiating-like population dependent on CBP/catenin transcription. Curr Mol Pharmacol 2013; 6: 204-10.
-
(2013)
Curr Mol Pharmacol
, vol.6
, pp. 204-210
-
-
Kida, A.1
Kahn, M.2
-
32
-
-
84873415451
-
Glucose-induced β-catenin acetylation enhances Wnt signaling in cancer
-
Chocarro-Calvo A, García-Martínez JM, Ardila-González S, De la Vieja A, García-Jiménez C. Glucose-induced β-catenin acetylation enhances Wnt signaling in cancer. Mol Cell 2013; 49: 474-86.
-
(2013)
Mol Cell
, vol.49
, pp. 474-486
-
-
Chocarro-Calvo, A.1
García-Martínez, J.M.2
Ardila-González, S.3
De la Vieja, A.4
García-Jiménez, C.5
-
33
-
-
30644458570
-
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin
-
Brembeck FH, Rosário M, Birchmeier W. Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. Curr Opin Genet Dev 2006; 16: 51-9.
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 51-59
-
-
Brembeck, F.H.1
Rosário, M.2
Birchmeier, W.3
-
34
-
-
80051544746
-
β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis
-
van Veelen W, Le NH, Helvensteijn W et al. β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis. Gut 2011; 60: 1204-12.
-
(2011)
Gut
, vol.60
, pp. 1204-1212
-
-
van Veelen, W.1
Le, N.H.2
Helvensteijn, W.3
-
35
-
-
80051497162
-
Prostaglandin E2 and pain - an update
-
Kawabata A. Prostaglandin E2 and pain - an update. Biol Pharm Bull 2011; 34: 1170-3.
-
(2011)
Biol Pharm Bull
, vol.34
, pp. 1170-1173
-
-
Kawabata, A.1
-
36
-
-
11144357877
-
Differences between human and mouse embryonic stem cells
-
Ginis , Luo Y, Miura T et al. Differences between human and mouse embryonic stem cells. Dev Biol 2004; 269: 360-80.
-
(2004)
Dev Biol
, vol.269
, pp. 360-380
-
-
Ginis, .1
Luo, Y.2
Miura, T.3
-
37
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004; 10: 55-63.
-
(2004)
Nat Med
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
38
-
-
0347359163
-
Wnt proteins promote neuronal differentiation in neural stem cell culture
-
Muroyama Y, Kondoh H, Takada S. Wnt proteins promote neuronal differentiation in neural stem cell culture. Biochem Biophys Res Commun 2004; 313: 915-21.
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 915-921
-
-
Muroyama, Y.1
Kondoh, H.2
Takada, S.3
-
39
-
-
28444438841
-
Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells
-
Dravid G, Ye Z, Hammond H et al. Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells 2005; 23: 1489-501.
-
(2005)
Stem Cells
, vol.23
, pp. 1489-1501
-
-
Dravid, G.1
Ye, Z.2
Hammond, H.3
-
40
-
-
0037135177
-
Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
-
Chenn A, Walsh CA. Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science 2002; 297: 365-9.
-
(2002)
Science
, vol.297
, pp. 365-369
-
-
Chenn, A.1
Walsh, C.A.2
-
41
-
-
0038517899
-
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system
-
Zehner D, Fujita Y, Hulsken J et al. beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. Dev Biol 2003; 258: 406-18.
-
(2003)
Dev Biol
, vol.258
, pp. 406-418
-
-
Zehner, D.1
Fujita, Y.2
Hulsken, J.3
-
42
-
-
0037049631
-
Lineage-specific requirements of beta-catenin in neural crest development
-
Hari L, Brault V, Kleber M et al. Lineage-specific requirements of beta-catenin in neural crest development. J Cell Biol 2002; 159: 867-80.
-
(2002)
J Cell Biol
, vol.159
, pp. 867-880
-
-
Hari, L.1
Brault, V.2
Kleber, M.3
-
43
-
-
84872498040
-
On the role of Wnt/β-catenin signaling in stem cells
-
Kühl SJ, Kühl M. On the role of Wnt/β-catenin signaling in stem cells. Biochim Biophys Acta 2013; 1830: 2297-306.
-
(2013)
Biochim Biophys Acta
, vol.1830
, pp. 2297-2306
-
-
Kühl, S.J.1
Kühl, M.2
-
44
-
-
84862170024
-
Drugging Wnt signalling in cancer
-
Erratum in: EMBO J. 2012; 31: 3375.
-
Polakis P. Drugging Wnt signalling in cancer. EMBO J 2012; 31: 2737-46. Erratum in: EMBO J. 2012; 31: 3375.
-
(2012)
EMBO J
, vol.31
, pp. 2737-2746
-
-
Polakis, P.1
-
45
-
-
84871846692
-
WNT signalling pathways as therapeutic targets in cancer
-
Anastas JN, Moon RT. WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer 2013; 13: 11-26.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 11-26
-
-
Anastas, J.N.1
Moon, R.T.2
-
46
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J, Thliveris A, Samowitz W et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 1991; 66: 589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
-
47
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler KW, Nilbert MC, Su LK et al. Identification of FAP locus genes from chromosome 5q21. Science 1991; 253: 661-5.
-
(1991)
Science
, vol.253
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.K.3
-
48
-
-
0041380990
-
Adenomatous polyposis coli/beta-catenin interaction and downstream targets: altered gene expression in gastrointestinal tumors
-
Clements WM, Lowy AM, Grode J. Adenomatous polyposis coli/beta-catenin interaction and downstream targets: altered gene expression in gastrointestinal tumors. Clin Colorectal Cancer 2003; 3: 113-20.
-
(2003)
Clin Colorectal Cancer
, vol.3
, pp. 113-120
-
-
Clements, W.M.1
Lowy, A.M.2
Grode, J.3
-
49
-
-
84873390533
-
Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability
-
Drier Y, Lawrence MS, Carter SL et al. Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability. Genome Res 2013; 23: 228-35.
-
(2013)
Genome Res
, vol.23
, pp. 228-235
-
-
Drier, Y.1
Lawrence, M.S.2
Carter, S.L.3
-
50
-
-
0030900696
-
Stabilization of beta-catenin by genetic defects in melanoma cell lines
-
Rubinfeld B, Robbins O, El-Gamil M, Albert I, Porfiri E, Polakis P. Stabilization of beta-catenin by genetic defects in melanoma cell lines. Science 1997; 275: 1790-2.
-
(1997)
Science
, vol.275
, pp. 1790-1792
-
-
Rubinfeld, B.1
Robbins, O.2
El-Gamil, M.3
Albert, I.4
Porfiri, E.5
Polakis, P.6
-
51
-
-
84864395840
-
WNT secretion and signalling in human disease
-
Herr P, Hausmann G, Basler K. WNT secretion and signalling in human disease. Trends Mol Med 2012; 18: 483-93.
-
(2012)
Trends Mol Med
, vol.18
, pp. 483-493
-
-
Herr, P.1
Hausmann, G.2
Basler, K.3
-
52
-
-
84872453498
-
Functional genomic studies: insights into the pathogenesis of liver cancer
-
Han ZG. Functional genomic studies: insights into the pathogenesis of liver cancer. Annu Rev Genomics Hum Genet 2012; 13: 171-205.
-
(2012)
Annu Rev Genomics Hum Genet
, vol.13
, pp. 171-205
-
-
Han, Z.G.1
-
55
-
-
84870252814
-
The complex world of WNT receptor signalling
-
Niehrs C. The complex world of WNT receptor signalling. Nat Rev Mol Cell Biol 2012; 13: 767-79.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 767-779
-
-
Niehrs, C.1
-
56
-
-
44949226873
-
Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness
-
Le NH, Franken P, Fodde R. Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness. Br J Cancer 2008; 98: 1886-93.
-
(2008)
Br J Cancer
, vol.98
, pp. 1886-1893
-
-
Le, N.H.1
Franken, P.2
Fodde, R.3
-
57
-
-
18244377210
-
Wnt/beta-catenin pathway
-
Moon RT. Wnt/beta-catenin pathway. Sci STKE 2005; 271: cm1.
-
(2005)
Sci STKE
, vol.271
, pp. cm1
-
-
Moon, R.T.1
-
58
-
-
78649318098
-
The Wnt signaling pathway in cellular proliferation and differentiation: a tale of two coactivators
-
Teo J-L, Kahn M. The Wnt signaling pathway in cellular proliferation and differentiation: a tale of two coactivators. Adv Drug Deliv Rev 2010; 62: 1149-55.
-
(2010)
Adv Drug Deliv Rev
, vol.62
, pp. 1149-1155
-
-
Teo, J.-L.1
Kahn, M.2
-
59
-
-
67649470380
-
Proximal events in Wnt signal transduction
-
Angers S, Moon RT. Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol 2009; 10: 468-77.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 468-477
-
-
Angers, S.1
Moon, R.T.2
-
60
-
-
0034141475
-
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
-
Kung AL, Rebel VI, Bronson RT et al. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev 2000; 14: 272-7.
-
(2000)
Genes Dev
, vol.14
, pp. 272-277
-
-
Kung, A.L.1
Rebel, V.I.2
Bronson, R.T.3
-
61
-
-
0036478904
-
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice
-
Yamauchi T, Oike Y, Kamon J et al. Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice. Nat Genet 2002; 30: 221-6.
-
(2002)
Nat Genet
, vol.30
, pp. 221-226
-
-
Yamauchi, T.1
Oike, Y.2
Kamon, J.3
-
62
-
-
0141753139
-
Differential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5
-
Roth FJ, Shikama N, Henzen C et al. Differential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5. EMBO J 2003; 2003: 5186-96.
-
(2003)
EMBO J
, vol.2003
, pp. 5186-5196
-
-
Roth, F.J.1
Shikama, N.2
Henzen, C.3
-
63
-
-
26944439459
-
Investigating Wnt signaling: a chemogenomic safari
-
McMillan M, Kahn M. Investigating Wnt signaling: a chemogenomic safari. Drug Discov Today 2005; 10: 1467-74.
-
(2005)
Drug Discov Today
, vol.10
, pp. 1467-1474
-
-
McMillan, M.1
Kahn, M.2
-
64
-
-
4344587136
-
A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]
-
Emami KH, Nguyen C, Ma H et al. A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]. Proc Natl Acad Sci USA 2004; 101: 12682-7.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 12682-12687
-
-
Emami, K.H.1
Nguyen, C.2
Ma, H.3
-
65
-
-
84872006171
-
Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion
-
Hasegawa K, Yasuda SY, Teo JL et al. Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion. Stem Cells Transl Med 2012; 1: 18-28.
-
(2012)
Stem Cells Transl Med
, vol.1
, pp. 18-28
-
-
Hasegawa, K.1
Yasuda, S.Y.2
Teo, J.L.3
-
66
-
-
84859098977
-
Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model
-
Banerjee ER, Laflamme MA, Papayannopoulou T, Kahn M, Murry CE, Henderson WR Jr. Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model. PLoS ONE 2012; 7: e33165.
-
(2012)
PLoS ONE
, vol.7
, pp. e33165
-
-
Banerjee, E.R.1
Laflamme, M.A.2
Papayannopoulou, T.3
Kahn, M.4
Murry, C.E.5
Henderson Jr, W.R.6
-
67
-
-
34248393912
-
Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency
-
Miyabayashi T, Teo JL, Yamamoto M, McMillan M, Nguyen C, Kahn M. Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency. Proc Natl Acad Sci USA 2007; 104: 5668-73.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5668-5673
-
-
Miyabayashi, T.1
Teo, J.L.2
Yamamoto, M.3
McMillan, M.4
Nguyen, C.5
Kahn, M.6
-
68
-
-
48149107133
-
Wnt signaling promotes reprogramming of somatic cells to pluripotency
-
Marson A, Foreman R, Chevalier B et al. Wnt signaling promotes reprogramming of somatic cells to pluripotency. Cell Stem Cell 2008; 3: 132-5.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 132-135
-
-
Marson, A.1
Foreman, R.2
Chevalier, B.3
-
69
-
-
79951577787
-
Recapitulation of the embryonic cardiovascular progenitor cell niche
-
Schenke-Layland K, Nsair A, Van Handel B et al. Recapitulation of the embryonic cardiovascular progenitor cell niche. Biomaterials 2011; 2: 2748-56.
-
(2011)
Biomaterials
, vol.2
, pp. 2748-2756
-
-
Schenke-Layland, K.1
Nsair, A.2
Van Handel, B.3
-
70
-
-
84880326552
-
Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours
-
Wend P, Fang L, Zhu Q et al. Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours. EMBO J 2013; 32: 1977-89.
-
(2013)
EMBO J
, vol.32
, pp. 1977-1989
-
-
Wend, P.1
Fang, L.2
Zhu, Q.3
-
71
-
-
84899625247
-
Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia
-
Gang EJ, Hsieh YT, Pham J et al. Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia. Oncogene 2014; 33: 2169-78.
-
(2014)
Oncogene
, vol.33
, pp. 2169-2178
-
-
Gang, E.J.1
Hsieh, Y.T.2
Pham, J.3
-
72
-
-
84885950154
-
Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway
-
He K, Xu T, Xu Y, Ring A, Kahn M, Goldkorn A. Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway. Int J Cancer 2014; 134: 43-54.
-
(2014)
Int J Cancer
, vol.134
, pp. 43-54
-
-
He, K.1
Xu, T.2
Xu, Y.3
Ring, A.4
Kahn, M.5
Goldkorn, A.6
-
73
-
-
77956288500
-
Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
-
Henderson WR Jr, Chi EY, Ye X et al. Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. Proc Natl Acad Sci USA 2010; 107: 14309-14.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14309-14314
-
-
Henderson Jr, W.R.1
Chi, E.Y.2
Ye, X.3
-
74
-
-
80052335469
-
Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis
-
Hao S, He W, Li Y et al. Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis. J Am Soc Nephrol 2011; 22: 1642-53.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1642-1653
-
-
Hao, S.1
He, W.2
Li, Y.3
-
75
-
-
84884172819
-
The small molecule Wnt signaling modulator ICG-001 improves contractile function in chronically infarcted rat myocardium
-
Sasaki T, Hwang H, Nguyen C, Kloner RA, Kahn M. The small molecule Wnt signaling modulator ICG-001 improves contractile function in chronically infarcted rat myocardium. PLoS ONE 2013; 8: e75010.
-
(2013)
PLoS ONE
, vol.8
, pp. e75010
-
-
Sasaki, T.1
Hwang, H.2
Nguyen, C.3
Kloner, R.A.4
Kahn, M.5
-
76
-
-
70349123829
-
The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells
-
Cicalese A, Bonizzi G, Pasi CE et al. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. Cell 2009; 138: 1083-95.
-
(2009)
Cell
, vol.138
, pp. 1083-1095
-
-
Cicalese, A.1
Bonizzi, G.2
Pasi, C.E.3
-
77
-
-
78049496814
-
mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion
-
Lee JY, Nakada D, Yilmaz OH et al. mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion. Cell Stem Cell 2010; 7: 593-905.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 593-905
-
-
Lee, J.Y.1
Nakada, D.2
Yilmaz, O.H.3
-
78
-
-
80054959395
-
Symmetric division versus asymmetric division: a tale of two coactivators
-
Kahn M. Symmetric division versus asymmetric division: a tale of two coactivators. Future Med Chem 2011; 3: 1745-63.
-
(2011)
Future Med Chem
, vol.3
, pp. 1745-1763
-
-
Kahn, M.1
-
79
-
-
79960474805
-
Chemical 'Jekyll and Hyde's: small-molecule inhibitors of developmental signaling pathways
-
Sakata T, Chen JK. Chemical 'Jekyll and Hyde's: small-molecule inhibitors of developmental signaling pathways. Chem Soc Rev 2011; 40: 4318-31.
-
(2011)
Chem Soc Rev
, vol.40
, pp. 4318-4331
-
-
Sakata, T.1
Chen, J.K.2
-
80
-
-
84884194711
-
A phase I first-in-human study of PRI-724 in patients (pts) with advanced solid tumors
-
Abstract .
-
El-Khoueiry AB, Ning Y, Yang D et al. A phase I first-in-human study of PRI-724 in patients (pts) with advanced solid tumors. J Clin Oncol 2013; 31(Suppl): Abstract 2501.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2501
-
-
El-Khoueiry, A.B.1
Ning, Y.2
Yang, D.3
|