메뉴 건너뛰기




Volumn 25, Issue 5, 2016, Pages 241-251

Inflammation after Ischemic stroke: The role of leukocytes and glial cells

Author keywords

Glial cells; Inflammation; Ischemic stroke; Leukocytes

Indexed keywords


EID: 84995600744     PISSN: 12262560     EISSN: 20938144     Source Type: Journal    
DOI: 10.5607/en.2016.25.5.241     Document Type: Review
Times cited : (248)

References (106)
  • 1
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: a sensor for pathological events in the CNS
    • Kreutzberg GW (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 2
    • 84899839720 scopus 로고    scopus 로고
    • Innate inflammatory responses in stroke: mechanisms and potential therapeutic targets
    • Kim JY, Kawabori M, Yenari MA (2014) Innate inflammatory responses in stroke: mechanisms and potential therapeutic targets. Curr Med Chem 21:2076-2097.
    • (2014) Curr Med Chem , vol.21 , pp. 2076-2097
    • Kim, J.Y.1    Kawabori, M.2    Yenari, M.A.3
  • 3
    • 0037046179 scopus 로고    scopus 로고
    • Randomized pilot study of nimesulide treatment in Alzheimer's disease
    • Aisen PS, Schmeidler J, Pasinetti GM (2002) Randomized pilot study of nimesulide treatment in Alzheimer's disease. Neurology 58:1050-1054.
    • (2002) Neurology , vol.58 , pp. 1050-1054
    • Aisen, P.S.1    Schmeidler, J.2    Pasinetti, G.M.3
  • 4
    • 0035105538 scopus 로고    scopus 로고
    • Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude
    • Mittelbronn M, Dietz K, Schluesener HJ, Meyermann R (2001) Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude. Acta Neuropathol 101:249-255.
    • (2001) Acta Neuropathol , vol.101 , pp. 249-255
    • Mittelbronn, M.1    Dietz, K.2    Schluesener, H.J.3    Meyermann, R.4
  • 5
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch UK, Kettenmann H (2007) Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 10:1387-1394.
    • (2007) Nat Neurosci , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 6
    • 0031982968 scopus 로고    scopus 로고
    • Inflammation and acute stroke
    • Becker KJ (1998) Inflammation and acute stroke. Curr Opin Neurol 11:45-49.
    • (1998) Curr Opin Neurol , vol.11 , pp. 45-49
    • Becker, K.J.1
  • 7
    • 0031298625 scopus 로고    scopus 로고
    • Increase in surface expression of ICAM-1, VCAM-1 and E-selectin in human cerebromicrovascular endothelial cells subjected to ischemia-like insults
    • Stanimirovic DB, Wong J, Shapiro A, Durkin JP (1997) Increase in surface expression of ICAM-1, VCAM-1 and E-selectin in human cerebromicrovascular endothelial cells subjected to ischemia-like insults. Acta Neurochir Suppl 70:12-16.
    • (1997) Acta Neurochir Suppl , vol.70 , pp. 12-16
    • Stanimirovic, D.B.1    Wong, J.2    Shapiro, A.3    Durkin, J.P.4
  • 8
    • 20344398223 scopus 로고    scopus 로고
    • Astrocyte activation and reactive gliosis
    • Pekny M, Nilsson M (2005) Astrocyte activation and reactive gliosis. Glia 50:427-434.
    • (2005) Glia , vol.50 , pp. 427-434
    • Pekny, M.1    Nilsson, M.2
  • 10
    • 0029692418 scopus 로고    scopus 로고
    • Significance of the inflammatory response in brain ischemia
    • Hallenbeck JM (1996) Significance of the inflammatory response in brain ischemia. Acta Neurochir Suppl 66:27-31.
    • (1996) Acta Neurochir Suppl , vol.66 , pp. 27-31
    • Hallenbeck, J.M.1
  • 12
    • 0035143182 scopus 로고    scopus 로고
    • Cerebral ischemia and inflammation
    • Iadecola C, Alexander M (2001) Cerebral ischemia and inflammation. Curr Opin Neurol 14:89-94.
    • (2001) Curr Opin Neurol , vol.14 , pp. 89-94
    • Iadecola, C.1    Alexander, M.2
  • 13
    • 33646454450 scopus 로고    scopus 로고
    • Role of T lymphocytes and interferon-gamma in ischemic stroke
    • Yilmaz G, Arumugam TV, Stokes KY, Granger DN (2006) Role of T lymphocytes and interferon-gamma in ischemic stroke. Circulation 113:2105-2112.
    • (2006) Circulation , vol.113 , pp. 2105-2112
    • Yilmaz, G.1    Arumugam, T.V.2    Stokes, K.Y.3    Granger, D.N.4
  • 14
    • 24744440988 scopus 로고    scopus 로고
    • Immunology of ischemic vascular disease: plaque to attack
    • Hallenbeck JM, Hansson GK, Becker KJ (2005) Immunology of ischemic vascular disease: plaque to attack. Trends Immunol 26:550-556.
    • (2005) Trends Immunol , vol.26 , pp. 550-556
    • Hallenbeck, J.M.1    Hansson, G.K.2    Becker, K.J.3
  • 16
    • 80355143546 scopus 로고    scopus 로고
    • Microglial cell origin and phenotypes in health and disease
    • Saijo K, Glass CK (2011) Microglial cell origin and phenotypes in health and disease. Nat Rev Immunol 11:775-787.
    • (2011) Nat Rev Immunol , vol.11 , pp. 775-787
    • Saijo, K.1    Glass, C.K.2
  • 18
  • 19
    • 33745761474 scopus 로고    scopus 로고
    • Microglia in cerebral ischemia: molecular actions and interactions
    • Lai AY, Todd KG (2006) Microglia in cerebral ischemia: molecular actions and interactions. Can J Physiol Pharmacol 84:49-59.
    • (2006) Can J Physiol Pharmacol , vol.84 , pp. 49-59
    • Lai, A.Y.1    Todd, K.G.2
  • 20
    • 0034114456 scopus 로고    scopus 로고
    • Cascading glia reactions: a common pathomechanism and its differentiated control by cyclic nucleotide signaling
    • Schubert P, Morino T, Miyazaki H, Ogata T, Nakamura Y, Marchini C, Ferroni S (2000) Cascading glia reactions: a common pathomechanism and its differentiated control by cyclic nucleotide signaling. Ann N Y Acad Sci 903:24-33.
    • (2000) Ann N Y Acad Sci , vol.903 , pp. 24-33
    • Schubert, P.1    Morino, T.2    Miyazaki, H.3    Ogata, T.4    Nakamura, Y.5    Marchini, C.6    Ferroni, S.7
  • 21
    • 84896689074 scopus 로고    scopus 로고
    • The role of the microglia in acute CNS injury
    • Kawabori M, Yenari MA (2015) The role of the microglia in acute CNS injury. Metab Brain Dis 30:381-392.
    • (2015) Metab Brain Dis , vol.30 , pp. 381-392
    • Kawabori, M.1    Yenari, M.A.2
  • 24
    • 0027238093 scopus 로고
    • Macrophage colony-stimulating factor in human fetal astrocytes and microglia. Differential regulation by cytokines and lipopolysaccharide, and modulation of class II MHC on microglia
    • Lee SC, Liu W, Roth P, Dickson DW, Berman JW, Brosnan CF (1993) Macrophage colony-stimulating factor in human fetal astrocytes and microglia. Differential regulation by cytokines and lipopolysaccharide, and modulation of class II MHC on microglia. J Immunol 150:594-604.
    • (1993) J Immunol , vol.150 , pp. 594-604
    • Lee, S.C.1    Liu, W.2    Roth, P.3    Dickson, D.W.4    Berman, J.W.5    Brosnan, C.F.6
  • 25
    • 0024401054 scopus 로고
    • Production of tumor necrosis factor-alpha by microglia and astrocytes in culture
    • Sawada M, Kondo N, Suzumura A, Marunouchi T (1989) Production of tumor necrosis factor-alpha by microglia and astrocytes in culture. Brain Res 491:394-397.
    • (1989) Brain Res , vol.491 , pp. 394-397
    • Sawada, M.1    Kondo, N.2    Suzumura, A.3    Marunouchi, T.4
  • 27
    • 36649022397 scopus 로고    scopus 로고
    • Inflammation in ischemic brain injury: timing is important
    • Kriz J (2006) Inflammation in ischemic brain injury: timing is important. Crit Rev Neurobiol 18:145-157.
    • (2006) Crit Rev Neurobiol , vol.18 , pp. 145-157
    • Kriz, J.1
  • 29
    • 26444558061 scopus 로고    scopus 로고
    • Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window
    • Yu YM, Kim JB, Lee KW, Kim SY, Han PL, Lee JK (2005) Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window. Stroke 36:2238-2243.
    • (2005) Stroke , vol.36 , pp. 2238-2243
    • Yu, Y.M.1    Kim, J.B.2    Lee, K.W.3    Kim, S.Y.4    Han, P.L.5    Lee, J.K.6
  • 30
    • 77952997178 scopus 로고    scopus 로고
    • Control of macrophage activation and function by PPARs
    • Chawla A (2010) Control of macrophage activation and function by PPARs. Circ Res 106:1559-1569.
    • (2010) Circ Res , vol.106 , pp. 1559-1569
    • Chawla, A.1
  • 32
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon S, Taylor PR (2005) Monocyte and macrophage heterogeneity. Nat Rev Immunol 5:953-964.
    • (2005) Nat Rev Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 34
    • 33746211119 scopus 로고    scopus 로고
    • Novel effector molecules in type 2 inflammation: lessons drawn from helminth infection and allergy
    • Nair MG, Guild KJ, Artis D (2006) Novel effector molecules in type 2 inflammation: lessons drawn from helminth infection and allergy. J Immunol 177:1393-1399.
    • (2006) J Immunol , vol.177 , pp. 1393-1399
    • Nair, M.G.1    Guild, K.J.2    Artis, D.3
  • 35
    • 70449526190 scopus 로고    scopus 로고
    • Heterogeneity of microglial activation in the innate immune response in the brain
    • Colton CA (2009) Heterogeneity of microglial activation in the innate immune response in the brain. J Neuroimmune Pharmacol 4:399-418.
    • (2009) J Neuroimmune Pharmacol , vol.4 , pp. 399-418
    • Colton, C.A.1
  • 37
    • 84868209611 scopus 로고    scopus 로고
    • Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia
    • Hu X, Li P, Guo Y, Wang H, Leak RK, Chen S, Gao Y, Chen J (2012) Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke 43:3063-3070.
    • (2012) Stroke , vol.43 , pp. 3063-3070
    • Hu, X.1    Li, P.2    Guo, Y.3    Wang, H.4    Leak, R.K.5    Chen, S.6    Gao, Y.7    Chen, J.8
  • 38
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP (2008) Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8:958-969.
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 40
    • 84958152299 scopus 로고    scopus 로고
    • Call off the dog(ma): M1/M2 polarization is concurrent following traumatic brain injury
    • Morganti JM, Riparip LK, Rosi S (2016) Call off the dog(ma): M1/M2 polarization is concurrent following traumatic brain injury. PLoS One 11:e0148001.
    • (2016) PLoS One , vol.11
    • Morganti, J.M.1    Riparip, L.K.2    Rosi, S.3
  • 44
    • 84873452455 scopus 로고    scopus 로고
    • Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states
    • Kumar A, Stoica BA, Sabirzhanov B, Burns MP, Faden AI, Loane DJ (2013) Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states. Neurobiol Aging 34:1397-1411.
    • (2013) Neurobiol Aging , vol.34 , pp. 1397-1411
    • Kumar, A.1    Stoica, B.A.2    Sabirzhanov, B.3    Burns, M.P.4    Faden, A.I.5    Loane, D.J.6
  • 47
    • 84923346682 scopus 로고    scopus 로고
    • Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke
    • Kawabori M, Kacimi R, Kauppinen T, Calosing C, Kim JY, Hsieh CL, Nakamura MC, Yenari MA (2015) Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke. J Neurosci 35:3384-3396.
    • (2015) J Neurosci , vol.35 , pp. 3384-3396
    • Kawabori, M.1    Kacimi, R.2    Kauppinen, T.3    Calosing, C.4    Kim, J.Y.5    Hsieh, C.L.6    Nakamura, M.C.7    Yenari, M.A.8
  • 48
    • 0345580623 scopus 로고    scopus 로고
    • Cytokine actions in the central nervous system
    • Benveniste EN (1998) Cytokine actions in the central nervous system. Cytokine Growth Factor Rev 9:259-275.
    • (1998) Cytokine Growth Factor Rev , vol.9 , pp. 259-275
    • Benveniste, E.N.1
  • 49
    • 45749140106 scopus 로고    scopus 로고
    • Spatiotemporal dynamics of astroglial and microglial responses after photothrombotic stroke in the rat brain
    • Nowicka D, Rogozinska K, Aleksy M, Witte OW, Skangiel-Kramska J (2008) Spatiotemporal dynamics of astroglial and microglial responses after photothrombotic stroke in the rat brain. Acta Neurobiol Exp (Warsz) 68:155-168.
    • (2008) Acta Neurobiol Exp (Warsz) , vol.68 , pp. 155-168
    • Nowicka, D.1    Rogozinska, K.2    Aleksy, M.3    Witte, O.W.4    Skangiel-Kramska, J.5
  • 51
    • 0035153212 scopus 로고    scopus 로고
    • Immune function of astrocytes
    • Dong Y, Benveniste EN (2001) Immune function of astrocytes. Glia 36:180-190.
    • (2001) Glia , vol.36 , pp. 180-190
    • Dong, Y.1    Benveniste, E.N.2
  • 52
    • 0028240615 scopus 로고
    • Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia
    • Endoh M, Maiese K, Wagner J (1994) Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia. Brain Res 651:92-100.
    • (1994) Brain Res , vol.651 , pp. 92-100
    • Endoh, M.1    Maiese, K.2    Wagner, J.3
  • 54
    • 13244257271 scopus 로고    scopus 로고
    • A soluble Fn14-Fc decoy receptor reduces infarct volume in a murine model of cerebral ischemia
    • Yepes M, Brown SA, Moore EG, Smith EP, Lawrence DA, Winkles JA (2005) A soluble Fn14-Fc decoy receptor reduces infarct volume in a murine model of cerebral ischemia. Am J Pathol 166:511-520.
    • (2005) Am J Pathol , vol.166 , pp. 511-520
    • Yepes, M.1    Brown, S.A.2    Moore, E.G.3    Smith, E.P.4    Lawrence, D.A.5    Winkles, J.A.6
  • 55
    • 53549132254 scopus 로고    scopus 로고
    • Cell adhesion molecules and ischemic stroke
    • Yilmaz G, Granger DN (2008) Cell adhesion molecules and ischemic stroke. Neurol Res 30:783-793.
    • (2008) Neurol Res , vol.30 , pp. 783-793
    • Yilmaz, G.1    Granger, D.N.2
  • 58
    • 0029972079 scopus 로고    scopus 로고
    • Antibodies against adhesion molecules reduce apoptosis after transient middle cerebral artery occlusion in rat brain
    • Chopp M, Li Y, Jiang N, Zhang RL, Prostak J (1996) Antibodies against adhesion molecules reduce apoptosis after transient middle cerebral artery occlusion in rat brain. J Cereb Blood Flow Metab 16:578-584.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 578-584
    • Chopp, M.1    Li, Y.2    Jiang, N.3    Zhang, R.L.4    Prostak, J.5
  • 59
    • 0033019214 scopus 로고    scopus 로고
    • Leukocyte-endothelial cell adhesion: avenues for therapeutic intervention
    • Panés J, Perry M, Granger DN (1999) Leukocyte-endothelial cell adhesion: avenues for therapeutic intervention. Br J Pharmacol 126:537-550.
    • (1999) Br J Pharmacol , vol.126 , pp. 537-550
    • Panés, J.1    Perry, M.2    Granger, D.N.3
  • 60
    • 0036897540 scopus 로고    scopus 로고
    • Inflammation and infection in clinical stroke
    • Emsley HC, Tyrrell PJ (2002) Inflammation and infection in clinical stroke. J Cereb Blood Flow Metab 22:1399-1419.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1399-1419
    • Emsley, H.C.1    Tyrrell, P.J.2
  • 61
    • 0031685143 scopus 로고    scopus 로고
    • The role of inflammation after acute stroke: utility of pursuing anti-adhesion molecule therapy
    • DeGraba TJ (1998) The role of inflammation after acute stroke: utility of pursuing anti-adhesion molecule therapy. Neurology 51:S62-S68.
    • (1998) Neurology , vol.51 , pp. S62-S68
    • DeGraba, T.J.1
  • 62
    • 2642550045 scopus 로고    scopus 로고
    • Leukocyteendothelium interactions during permanent focal cerebral ischemia in mice
    • Kataoka H, Kim SW, Plesnila N (2004) Leukocyteendothelium interactions during permanent focal cerebral ischemia in mice. J Cereb Blood Flow Metab 24:668-676.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 668-676
    • Kataoka, H.1    Kim, S.W.2    Plesnila, N.3
  • 64
    • 84907021173 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase in neutrophils and endothelium contributes to ischemic brain injury in mice
    • Garcia-Bonilla L, Moore JM, Racchumi G, Zhou P, Butler JM, Iadecola C, Anrather J (2014) Inducible nitric oxide synthase in neutrophils and endothelium contributes to ischemic brain injury in mice. J Immunol 193:2531-2537.
    • (2014) J Immunol , vol.193 , pp. 2531-2537
    • Garcia-Bonilla, L.1    Moore, J.M.2    Racchumi, G.3    Zhou, P.4    Butler, J.M.5    Iadecola, C.6    Anrather, J.7
  • 65
    • 84890123003 scopus 로고    scopus 로고
    • Neutrophil interactions with the vascular endothelium
    • Dimasi D, Sun WY, Bonder CS (2013) Neutrophil interactions with the vascular endothelium. Int Immunopharmacol 17:1167-1175.
    • (2013) Int Immunopharmacol , vol.17 , pp. 1167-1175
    • Dimasi, D.1    Sun, W.Y.2    Bonder, C.S.3
  • 66
    • 0037312886 scopus 로고    scopus 로고
    • Inflammatory mechanisms after ischemia and stroke
    • Danton GH, Dietrich WD (2003) Inflammatory mechanisms after ischemia and stroke. J Neuropathol Exp Neurol 62:127-136.
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 127-136
    • Danton, G.H.1    Dietrich, W.D.2
  • 67
    • 0347356514 scopus 로고    scopus 로고
    • Inhibition of intercellular adhesion molecule-1 protein expression by antisense oligonucleotides is neuroprotective after transient middle cerebral artery occlusion in rat
    • Vemuganti R, Dempsey RJ, Bowen KK (2004) Inhibition of intercellular adhesion molecule-1 protein expression by antisense oligonucleotides is neuroprotective after transient middle cerebral artery occlusion in rat. Stroke 35:179-184.
    • (2004) Stroke , vol.35 , pp. 179-184
    • Vemuganti, R.1    Dempsey, R.J.2    Bowen, K.K.3
  • 70
    • 0032192489 scopus 로고    scopus 로고
    • Hu23F2G, an antibody recognizing the leukocyte CD11/CD18 integrin, reduces injury in a rabbit model of transient focal cerebral ischemia
    • Yenari MA, Kunis D, Sun GH, Onley D, Watson L, Turner S, Whitaker S, Steinberg GK (1998) Hu23F2G, an antibody recognizing the leukocyte CD11/CD18 integrin, reduces injury in a rabbit model of transient focal cerebral ischemia. Exp Neurol 153:223-233.
    • (1998) Exp Neurol , vol.153 , pp. 223-233
    • Yenari, M.A.1    Kunis, D.2    Sun, G.H.3    Onley, D.4    Watson, L.5    Turner, S.6    Whitaker, S.7    Steinberg, G.K.8
  • 71
    • 0038506990 scopus 로고    scopus 로고
    • Effects of a selective CD11b/CD18 antagonist and recombinant human tissue plasminogen activator treatment alone and in combination in a rat embolic model of stroke
    • Zhang L, Zhang ZG, Zhang RL, Lu M, Krams M, Chopp M (2003) Effects of a selective CD11b/CD18 antagonist and recombinant human tissue plasminogen activator treatment alone and in combination in a rat embolic model of stroke. Stroke 34:1790-1795.
    • (2003) Stroke , vol.34 , pp. 1790-1795
    • Zhang, L.1    Zhang, Z.G.2    Zhang, R.L.3    Lu, M.4    Krams, M.5    Chopp, M.6
  • 72
    • 0030013371 scopus 로고    scopus 로고
    • Cytokines and adhesion molecules in stroke and related diseases
    • Kim JS (1996) Cytokines and adhesion molecules in stroke and related diseases. J Neurol Sci 137:69-78.
    • (1996) J Neurol Sci , vol.137 , pp. 69-78
    • Kim, J.S.1
  • 73
    • 0032473602 scopus 로고    scopus 로고
    • The expression of P-and E-selectins in three models of middle cerebral artery occlusion
    • Zhang R, Chopp M, Zhang Z, Jiang N, Powers C (1998) The expression of P-and E-selectins in three models of middle cerebral artery occlusion. Brain Res 785:207-214.
    • (1998) Brain Res , vol.785 , pp. 207-214
    • Zhang, R.1    Chopp, M.2    Zhang, Z.3    Jiang, N.4    Powers, C.5
  • 74
    • 0028143514 scopus 로고
    • Neutrophils roll on adherent neutrophils bound to cytokineinduced endothelial cells via L-selectin on the rolling cells
    • Bargatze RF, Kurk S, Butcher EC, Jutila MA (1994) Neutrophils roll on adherent neutrophils bound to cytokineinduced endothelial cells via L-selectin on the rolling cells. J Exp Med 180:1785-1792.
    • (1994) J Exp Med , vol.180 , pp. 1785-1792
    • Bargatze, R.F.1    Kurk, S.2    Butcher, E.C.3    Jutila, M.A.4
  • 75
    • 33746861531 scopus 로고    scopus 로고
    • Cerebrovascular protection by various nitric oxide donors in rats after experimental stroke
    • Khan M, Jatana M, Elango C, Paintlia AS, Singh AK, Singh I (2006) Cerebrovascular protection by various nitric oxide donors in rats after experimental stroke. Nitric Oxide 15:114-124.
    • (2006) Nitric Oxide , vol.15 , pp. 114-124
    • Khan, M.1    Jatana, M.2    Elango, C.3    Paintlia, A.S.4    Singh, A.K.5    Singh, I.6
  • 77
    • 0034080318 scopus 로고    scopus 로고
    • The biology of chemokines and their receptors
    • Rossi D, Zlotnik A (2000) The biology of chemokines and their receptors. Annu Rev Immunol 18:217-242.
    • (2000) Annu Rev Immunol , vol.18 , pp. 217-242
    • Rossi, D.1    Zlotnik, A.2
  • 78
    • 33748142935 scopus 로고    scopus 로고
    • ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets
    • Bizzarri C, Beccari AR, Bertini R, Cavicchia MR, Giorgini S, Allegretti M (2006) ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets. Pharmacol Ther 112:139-149.
    • (2006) Pharmacol Ther , vol.112 , pp. 139-149
    • Bizzarri, C.1    Beccari, A.R.2    Bertini, R.3    Cavicchia, M.R.4    Giorgini, S.5    Allegretti, M.6
  • 79
  • 81
    • 79151470215 scopus 로고    scopus 로고
    • Chemokine-related gene expression in the brain following ischemic stroke: no role for CXCR2 in outcome
    • Brait VH, Rivera J, Broughton BR, Lee S, Drummond GR, Sobey CG (2011) Chemokine-related gene expression in the brain following ischemic stroke: no role for CXCR2 in outcome. Brain Res 1372:169-179.
    • (2011) Brain Res , vol.1372 , pp. 169-179
    • Brait, V.H.1    Rivera, J.2    Broughton, B.R.3    Lee, S.4    Drummond, G.R.5    Sobey, C.G.6
  • 82
    • 34250675226 scopus 로고    scopus 로고
    • The interleukin-8 (IL-8/CXCL8) receptor inhibitor reparixin improves neurological deficits and reduces longterm inflammation in permanent and transient cerebral ischemia in rats
    • Villa P, Triulzi S, Cavalieri B, Di Bitondo R, Bertini R, Barbera S, Bigini P, Mennini T, Gelosa P, Tremoli E, Sironi L, Ghezzi P (2007) The interleukin-8 (IL-8/CXCL8) receptor inhibitor reparixin improves neurological deficits and reduces longterm inflammation in permanent and transient cerebral ischemia in rats. Mol Med 13:125-133.
    • (2007) Mol Med , vol.13 , pp. 125-133
    • Villa, P.1    Triulzi, S.2    Cavalieri, B.3    Di Bitondo, R.4    Bertini, R.5    Barbera, S.6    Bigini, P.7    Mennini, T.8    Gelosa, P.9    Tremoli, E.10    Sironi, L.11    Ghezzi, P.12
  • 83
    • 67649404131 scopus 로고    scopus 로고
    • Blood monocytes: development, heterogeneity, and relationship with dendritic cells
    • Auffray C, Sieweke MH, Geissmann F (2009) Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu Rev Immunol 27:669-692.
    • (2009) Annu Rev Immunol , vol.27 , pp. 669-692
    • Auffray, C.1    Sieweke, M.H.2    Geissmann, F.3
  • 84
    • 84901358607 scopus 로고    scopus 로고
    • Monocytes and macrophages: developmental pathways and tissue homeostasis
    • Ginhoux F, Jung S (2014) Monocytes and macrophages: developmental pathways and tissue homeostasis. Nat Rev Immunol 14:392-404.
    • (2014) Nat Rev Immunol , vol.14 , pp. 392-404
    • Ginhoux, F.1    Jung, S.2
  • 87
    • 0028893614 scopus 로고
    • Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat
    • Kim JS, Gautam SC, Chopp M, Zaloga C, Jones ML, Ward PA, Welch KM (1995) Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat. J Neuroimmunol 56:127-134.
    • (1995) J Neuroimmunol , vol.56 , pp. 127-134
    • Kim, J.S.1    Gautam, S.C.2    Chopp, M.3    Zaloga, C.4    Jones, M.L.5    Ward, P.A.6    Welch, K.M.7
  • 88
    • 0028826503 scopus 로고
    • Induced expression of adhesion molecules following focal brain ischemia
    • Wang X, Feuerstein GZ (1995) Induced expression of adhesion molecules following focal brain ischemia. J Neurotrauma 12:825-832.
    • (1995) J Neurotrauma , vol.12 , pp. 825-832
    • Wang, X.1    Feuerstein, G.Z.2
  • 90
    • 34247874753 scopus 로고    scopus 로고
    • Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice
    • Dimitrijevic OB, Stamatovic SM, Keep RF, Andjelkovic AV (2007) Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice. Stroke 38:1345-1353.
    • (2007) Stroke , vol.38 , pp. 1345-1353
    • Dimitrijevic, O.B.1    Stamatovic, S.M.2    Keep, R.F.3    Andjelkovic, A.V.4
  • 91
    • 68649107955 scopus 로고    scopus 로고
    • The role of CC chemokine receptor 2 on microglia activation and blood-borne cell recruitment after transient focal cerebral ischemia in mice
    • Schilling M, Strecker JK, Ringelstein EB, Schäbitz WR, Kiefer R (2009) The role of CC chemokine receptor 2 on microglia activation and blood-borne cell recruitment after transient focal cerebral ischemia in mice. Brain Res 1289:79-84.
    • (2009) Brain Res , vol.1289 , pp. 79-84
    • Schilling, M.1    Strecker, J.K.2    Ringelstein, E.B.3    Schäbitz, W.R.4    Kiefer, R.5
  • 92
    • 84885356418 scopus 로고    scopus 로고
    • A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease
    • Naert G, Rivest S (2013) A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease. J Mol Cell Biol 5:284-293.
    • (2013) J Mol Cell Biol , vol.5 , pp. 284-293
    • Naert, G.1    Rivest, S.2
  • 95
    • 0037023216 scopus 로고    scopus 로고
    • The use of flow cytometry to evaluate temporal changes in inflammatory cells following focal cerebral ischemia in mice
    • Stevens SL, Bao J, Hollis J, Lessov NS, Clark WM, Stenzel-Poore MP (2002) The use of flow cytometry to evaluate temporal changes in inflammatory cells following focal cerebral ischemia in mice. Brain Res 932:110-119.
    • (2002) Brain Res , vol.932 , pp. 110-119
    • Stevens, S.L.1    Bao, J.2    Hollis, J.3    Lessov, N.S.4    Clark, W.M.5    Stenzel-Poore, M.P.6
  • 96
    • 0034746690 scopus 로고    scopus 로고
    • Antibody to the alpha4 integrin decreases infarct size in transient focal cerebral ischemia in rats
    • Becker K, Kindrick D, Relton J, Harlan J, Winn R (2001) Antibody to the alpha4 integrin decreases infarct size in transient focal cerebral ischemia in rats. Stroke 32:206-211.
    • (2001) Stroke , vol.32 , pp. 206-211
    • Becker, K.1    Kindrick, D.2    Relton, J.3    Harlan, J.4    Winn, R.5
  • 100
    • 0346458629 scopus 로고    scopus 로고
    • Neurotoxic effects of polymorphonuclear granulocytes on hippocampal primary cultures
    • Dinkel K, Dhabhar FS, Sapolsky RM (2004) Neurotoxic effects of polymorphonuclear granulocytes on hippocampal primary cultures. Proc Natl Acad Sci U S A 101:331-336.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 331-336
    • Dinkel, K.1    Dhabhar, F.S.2    Sapolsky, R.M.3
  • 103
    • 80053604734 scopus 로고    scopus 로고
    • Functional innervation of hepatic iNKT cells is immunosuppressive following stroke
    • Wong CH, Jenne CN, Lee WY, Léger C, Kubes P (2011) Functional innervation of hepatic iNKT cells is immunosuppressive following stroke. Science 334:101-105.
    • (2011) Science , vol.334 , pp. 101-105
    • Wong, C.H.1    Jenne, C.N.2    Lee, W.Y.3    Léger, C.4    Kubes, P.5
  • 105
    • 0036595397 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes: all roads lead to death
    • Barry M, Bleackley RC (2002) Cytotoxic T lymphocytes: all roads lead to death. Nat Rev Immunol 2:401-409.
    • (2002) Nat Rev Immunol , vol.2 , pp. 401-409
    • Barry, M.1    Bleackley, R.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.