Immunodeficiency reduces neural stem/progenitor cell apoptosis and enhances neurogenesis in the cerebral cortex after stroke

Journal of Neuroscience Research

Volumn 88, Issue 11, 2010, Pages 2385-2397

  Saino, Orie ^a   Taguchi, Akihiko ^b   Nakagomi, Takayuki ^a   Nakano Doi, Akiko ^a   Kashiwamura, Shin Ichiro ^a   Doe, Nobutaka ^a   Nakagomi, Nami ^a   Soma, Toshihiro ^a   Yoshikawa, Hiroo ^a   Stern, David M ^c   Okamura, Haruki ^a   Matsuyama, Tomohiro ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Adult stem cells; Apoptosis; CD4+ T cell; Cerebral cortex; Inflammation; Ischemia; Lymphocyte; Neural stem cells

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION; BRAIN INJURY; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL REGENERATION; CELL SURVIVAL; CELL THERAPY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CONVALESCENCE; IMMUNE DEFICIENCY; LYMPHOCYTE SUBPOPULATION; MALE; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REGULATORY T LYMPHOCYTE; SCID MOUSE; STEM CELL; STROKE; WILD TYPE; ANIMAL; ANIMAL BEHAVIOR; BRAIN ISCHEMIA; C57BL MOUSE; CELL DEATH; CEREBRAL INFARCTION; GENETICS; GLIA; HEMISPHERIC DOMINANCE; IMMUNOCOMPETENCE; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; METABOLISM; NERVE CELL; NICK END LABELING; PATHOLOGY; PHYSIOLOGY; PSYCHOLOGY; TRANSIENT ISCHEMIC ATTACK; TRANSPLANTATION;

CASPASE 3; INTERLEUKIN 2 RECEPTOR ALPHA;

ANIMALS; APOPTOSIS; BEHAVIOR, ANIMAL; BRAIN ISCHEMIA; CASPASE 3; CD4-POSITIVE T-LYMPHOCYTES; CELL DEATH; CEREBRAL CORTEX; CEREBRAL INFARCTION; FUNCTIONAL LATERALITY; IMMUNOCOMPETENCE; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSION; IN SITU NICK-END LABELING; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; ISCHEMIC ATTACK, TRANSIENT; MALE; MICE; MICE, INBRED C57BL; MICE, SCID; NEUROGENESIS; NEUROGLIA; NEURONS; RECOVERY OF FUNCTION; STEM CELLS; STROKE;

EID: 77955370220     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22410     Document Type: Article

References (36)

1. Arvidsson A, Collin T, Kirik D, Kokaia Z, Lindvall O. 2002. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 8:963-970. (Pubitemid 35033700)
2. + lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. J Clin Invest 119:182-192.
3. Brown KM, Donohue DE, D'Alessandro G, Ascoli GA. 2005. A cross-platform freeware tool for digital reconstruction of neuronal arborizations from image stacks. Neuroinformatics 3:343-360.
4. Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M. 2006. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol Cell Neurosci 31:149-160.
5. Chen H, Chopp M, Schultz L, Bodzin G, Garcia JH. 1993. Sequential neuronal and astrocytic changes after transient middle cerebral artery occlusion in the rat. J Neurol Sci 118:109-106. (Pubitemid 23268380)
6. Clausen BH, Lambertsen KL, Babcock AA, Holm TH, Dagnaes-Hansen F, Finsen B. 2008. Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice. J Neuroinflamm 5:46.
7. Corsini NS, Sancho-Martinez I, Laudenklos S, Glagow D, Kumar S, Letellier E, Koch P, Teodorczyk M, Kleber S, Klussmann S, Wiestler B, Brustle O, Mueller W, Gieffers C, Hill O, Thiemann M, Seedorf M, Gretz N, Sprengel R, Celikel T, Martin-Villalba A. 2009. The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair. Cell Stem Cell 5:178-190.
8. + T-cells in the development of MS. Neurol Res 28:245-249.
9. Hurn PD, Subramanian S, Parker SM, Afentoulis ME, Kaler LJ, Vandenbark AA, Offner H. 2007. T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation. J Cereb Blood Flow Metab 27:1798-1805.
10. Ito D, Tanaka K, Suzuki S, Dembo T, Fukuuchi Y. 2001. Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain. Stroke 32:1208-1215.
11. Itoh T, Satou T, Hashimoto S, Ito H. 2005. Isolation of neural stem cells from damaged rat cerebral cortex after traumatic brain injury. Neuroreport 16:1687-1691. (Pubitemid 41805804)
12. Jakubs K, Bonde S, Iosif RE, Ekdahl CT, Kokaia Z, Kokaia M, Lindvall O. 2008. Inflammation regulates functional integration of neurons born in adult brain. J Neurosci 28:12477-12488.
13. Kitano H, Nishimura H, Tachibana H, Yoshikawa H, Matsuyama T. 2004. ORP150 ameliorates ischemia/reperfusion injury from middle cerebral artery occlusion in mouse brain. Brain Res 1015:122-128.
14. Kriegstein A, Alvarez-Buylla A. 2009. The glial nature of embryonic and adult neural stem cells. Annu Rev Neurosci 32:149-184.
15. Lambertsen KL, Clausen BH, Babcock AA, Gregersen R, Fenger C, Nielsen HH, Haugaard LS, Wirenfeldt M, Nielsen M, Dagnaes-Hansen F, Bluethmann H, Faergeman NJ, Meldgaard M, Deierborg T, Finsen B. 2009. Microglia protect neurons against ischemia by synthesis of tumor necrosis factor. J Neurosci 29:1319-1330.
16. Liesz A, Suri-Payer E, Veltkamp C, Doerr H, Sommer C, Rivest S, Giese T, Veltkamp R. 2009. Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke. Nat Med 15:192-199.
17. Liu T, McDonnell PC, Young PR, White RF, Siren AL, Hallenbeck JM, Barone FC, Feurestein GZ. 1993. Interleukin-1 beta mRNA expression in ischemic rat cortex. Stroke 24:1746-1750; discussion 1750-1741.
18. Lorke DE, Ip CW, Schumacher U. 2008. Increased number of microglia in the brain of severe combined immunodeficient (SCID) mice. Histochem Cell Biol 130:693-697.
19. Mannick JB, Hausladen A, Liu L, Hess DT, Zeng M, Miao QX, Kane LS, Gow AJ, Stamler JS. 1999. Fas-induced caspase denitrosylation. Science 284:651-654.
20. Matsushita K, Matsuyama T, Nishimura H, Takaoka T, Kuwabara K, Tsukamoto Y, Sugita M, Ogawa S. 1998. Marked, sustained expression of a novel 150-kDa oxygen-regulated stress protein, in severely ischemic mouse neurons. Brain Res Mol Brain Res 60:98-106. (Pubitemid 28433199)
21. Mezey E, Key S, Vogelsang G, Szalayova I, Lange GD, Crain B. 2003. Transplanted bone marrow generates new neurons in human brains. Proc Natl Acad Sci U S A 100:1364-1369.
22. Morgan MJ, Kim YS, Liu ZG. 2009. Membrane-bound Fas ligand requires RIP1 for efficient activation of caspase-8 within the death-inducing signaling complex. J Immunol 183:3278-3284.
23. Mukherji B, Guha A, Chakraborty NG, Sivanandham M, Nashed AL, Sporn JR, Ergin MT. 1989. Clonal analysis of cytotoxic and regulatory T cell responses against human melanoma. J Exp Med 169:1961-1976.
24. Mukherji B, Chakraborty NG, Sivanandham M. 1990. T-cell clones that react against autologous human tumors. Immunol Rev 116:33-62. (Pubitemid 20283615)
25. Nakagomi T, Taguchi A, Fujimori Y, Saino O, Nakano-Doi A, Kubo S, Gotoh A, Soma T, Yoshikawa H, Nishizaki T, Nakagomi N, Stern DM, Matsuyama T. 2009. Isolation and characterization of neural stem/progenitor cells from post-stroke cerebral cortex in mice. Eur J Neurosci 29:1842-1852.
26. Niho Y, Asano Y. 1998. Fas/Fas ligand and hematopoietic progenitor cells. Curr Opin Hematol 5:163-165. (Pubitemid 28360539)
27. Nishi T, Maier CM, Hayashi T, Saito A, Chan PH. 2005. Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia. J Cereb Blood Flow Metab 25:1312-1324.
28. Okano H, Sawamoto K. 2008. Neural stem cells: involvement in adult neurogenesis and CNS repair. Philos Trans R Soc Lond B Biol Sci 363:2111-2122. (Pubitemid 351693525)
29. O'Reilly LA, Tai L, Lee L, Kruse EA, Grabow S, Fairlie WD, Haynes NM, Tarlinton DM, Zhang J-G, Belz GT, Smyth MJ, Bouillet P, Robb L, Strasser A. 2009. Membrane-bound Fas ligand only is essential for Fas-induced apoptosis. Nature 461:659-663.
30. Popovich PG, Longbrake EE. 2008. Can the immune system be harnessed to repair the CNS? Nat Rev Neurosci 9:481-493.
31. Rasley A, Tranguch SL, Rati DM, Marriott I. 2006. Murine glia express the immunosuppressive cytokine, interleukin-10, following exposure to Borrelia burgdorferi or Neisseria meningitidis. Glia 53:583-592.
32. Taguchi A, Soma T, Tanaka H, Kanda T, Nishimura H, Yoshikawa H, Tsukamoto Y, Iso H, Fujimori Y, Stern DM, Naritomi H, Matsuyama T. 2004. Administration of CD341 cells after stroke enhances neurogenesis via angiogenesis in a mouse model. J Clin Invest 114:330-338.
33. Taguchi A, Wen Z, Myojin K, Yoshihara T, Nakagomi T, Nakayama D, Tanaka H, Soma T, Stern DM, Naritomi H, Matsuyama T. 2007. Granulocyte colony-stimulating factor has a negative effect on stroke outcome in a murine model. Eur J Neurosci 26:126-133.
34. Uno H, Matsuyama T, Akita H, Nishimura H, Sugita M. 1997. Induction of tumor necrosis factor-alpha in the mouse hippocampus following transient forebrain ischemia. J Cereb Blood Flow Metab 17:491-499. (Pubitemid 27250975)
35. Van Beek J, Chan P, Bernaudin M, Petit E, MacKenzie ET, Fontaine M. 2000. Glial responses, clusterin, and complement in permanent focal cerebral ischemia in the mouse. Glia 31:39-50. (Pubitemid 30410872)
36. Yilmaz G, Arumugam TV, Stokes KY, Granger DN. 2006. Role of T lymphocytes and interferon-gamma in ischemic stroke. Circulation 113:2105-2112. (Pubitemid 43755161)