Chemokine-related gene expression in the brain following ischemic stroke: No role for CXCR2 in outcome

Brain Research

Volumn 1372, Issue , 2011, Pages 169-179

  Brait, Vanessa H ^a   Rivera, Jennifer ^a   Broughton, Brad R S ^a   Lee, Seyoung ^a   Drummond, Grant R ^a   Sobey, Christopher G ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Chemokines; CXCL1; CXCL2; CXCR2; Mouse; Stroke

Indexed keywords

1 (2 BROMOPHENYL) 3 (2 HYDROXY 4 NITROPHENYL)UREA; ALTEPLASE; CHEMOKINE; CHEMOKINE RECEPTOR CXCR2; CHEMOKINE RECEPTOR CXCR2 ANTAGONIST; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; MESSENGER RNA; MYELOPEROXIDASE; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN EDEMA; BRAIN FUNCTION; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFICACY; GENE EXPRESSION; HISTOLOGY; MALE; MONOCYTE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPERFUSION; SCREENING;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN; BRAIN EDEMA; BRAIN INFARCTION; CHEMOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; INFARCTION, MIDDLE CEREBRAL ARTERY; LASER-DOPPLER FLOWMETRY; MALE; MICE; MICE, INBRED C57BL; NEUTROPHILS; PHENYLUREA COMPOUNDS; RECOVERY OF FUNCTION; RNA, MESSENGER; TIME FACTORS;

MUS;

EID: 79151470215     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.11.087     Document Type: Article

References (44)

1. A. Al-Bahrani, S. Taha, H. Shaath, and M. Bakhiet TNF-alpha and IL-8 in acute stroke and the modulation of these cytokines by antiplatelet agents Curr. Neurovasc. Res. 4 2007 31 37
2. D.A. Armstrong, J.A. Major, A. Chudyk, and T.A. Hamilton Neutrophil chemoattractant genes KC and MIP-2 are expressed in different cell populations at sites of surgical injury J. Leukoc. Biol. 75 2004 641 648
3. A.F. Bento, D.F. Leite, R.F. Claudino, D.B. Hara, P.C. Leal, and J.B. Calixto The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice J. Leukoc. Biol. 84 2008 1213 1221
4. V. Beray-Berthat, B. Palmier, M. Plotkine, and I. Margaill Neutrophils do not contribute to infarction, oxidative stress, and NO synthase activity in severe brain ischemia Exp. Neurol. 182 2003 446 454
5. C. Bizzarri, A.R. Beccari, R. Bertini, M.R. Cavicchia, S. Giorgini, and M. Allegretti ELR + CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets Pharmacol. Ther. 112 2006 139 149
6. V.H. Brait, K.A. Jackman, A.K. Walduck, S. Selemidis, H. Diep, A.E. Mast, E. Guida, B.R. Broughton, G.R. Drummond, and C.G. Sobey Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide J. Cereb. Blood Flow Metab. 30 2010 1306 1317
7. D.R. Call, J.A. Nemzek, S.J. Ebong, G.R. Bolgos, D.E. Newcomb, G.K. Wollenberg, and D.G. Remick Differential local and systemic regulation of the murine chemokines KC and MIP2 Shock 15 2001 278 284
8. M. Campanella, C. Sciorati, G. Tarozzo, and M. Beltramo Flow cytometric analysis of inflammatory cells in ischemic rat brain Stroke 33 2002 586 592
9. K.Z. Chapman, V.Q. Dale, A. Denes, G. Bennett, N.J. Rothwell, S.M. Allan, and B.W. McColl A rapid and transient peripheral inflammatory response precedes brain inflammation after experimental stroke J. Cereb. Blood Flow Metab. 29 2009 1764 1768
10. E.S. Connolly Jr., C.J. Winfree, T.A. Springer, Y. Naka, H. Liao, S.D. Yan, D.M. Stern, R.A. Solomon, J.C. Gutierrez-Ramos, and D.J. Pinsky Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke J. Clin. Invest. 97 1996 209 216
11. G.J. del Zoppo, J.L. Saver, E.C. Jauch, H.P. Adams Jr., and Behalf of the American Heart Association Stroke Council Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator Stroke 40 2009 2945 2948
12. V. Di Cioccio, R. Strippoli, C. Bizzarri, G. Troiani, M.N. Cervellera, I. Gloaguen, A. Colagrande, E.M. Cattozzo, S. Pagliei, A. Santoni, F. Colotta, F. Mainiero, and R. Bertini Key role of proline-rich tyrosine kinase 2 in interleukin-8 (CXCL8/IL-8)-mediated human neutrophil chemotaxis Immunology 111 2004 407 415
13. U. Dirnagl, C. Iadecola, and M.A. Moskowitz Pathobiology of ischaemic stroke: an integrated view Trends Neurosci. 22 1999 391 397
14. D.F. Emerich, R.L. Dean III, and R.T. Bartus The role of leukocytes following cerebral ischemia: pathogenic variable or bystander reaction to emerging infarct? Exp. Neurol. 173 2002 168 181
15. M. Gelderblom, F. Leypoldt, K. Steinbach, D. Behrens, C.U. Choe, D.A. Siler, T.V. Arumugam, E. Orthey, C. Gerloff, E. Tolosa, and T. Magnus Temporal and spatial dynamics of cerebral immune cell accumulation in stroke Stroke 40 2009 1849 1857
16. C. Gerard, and B.J. Rollins Chemokines and disease Nat. Immunol. 2 2001 108 115
17. A.K. Harris, A. Ergul, A. Kozak, L.S. Machado, M.H. Johnson, and S.C. Fagan Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke BMC Neurosci. 6 2005 49
18. K.A. Jackman, A.A. Miller, T.M. De Silva, P.J. Crack, G.R. Drummond, and C.G. Sobey Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice Br. J. Pharmacol. 156 2009 680 688
19. N. Jiang, M. Chopp, and S. Chahwala Neutrophil inhibitory factor treatment of focal cerebral ischemia in the rat Brain Res. 788 1998 25 34
20. T. Kielian, B. Barry, and W.F. Hickey CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses J. Immunol. 166 2001 4634 4643
21. N. Kostulas, P. Kivisakk, Y. Huang, D. Matusevicius, V. Kostulas, and H. Link Ischemic stroke is associated with a systemic increase of blood mononuclear cells expressing interleukin-8 mRNA Stroke 29 1998 462 466
22. N. Kostulas, S.H. Pelidou, P. Kivisakk, V. Kostulas, and H. Link Increased IL-1beta, IL-8, and IL-17 mRNA expression in blood mononuclear cells observed in a prospective ischemic stroke study Stroke 30 1999 2174 2179
23. J. Lee, G. Cacalano, T. Camerato, K. Toy, M.W. Moore, and W.I. Wood Chemokine binding and activities mediated by the mouse IL-8 receptor J. Immunol. 155 1995 2158 2164
24. U. Lippert, K. Zachmann, B.M. Henz, and C. Neumann Human T lymphocytes and mast cells differentially express and regulate extra- and intracellular CXCR1 and CXCR2 Exp. Dermatol. 13 2004 520 525
25. A. Ludwig, J.E. Ehlert, H.D. Flad, and E. Brandt Identification of distinct surface-expressed and intracellular CXC-chemokine receptor 2 glycoforms in neutrophils: N-glycosylation is essential for maintenance of receptor surface expression J. Immunol. 165 2000 1044 1052
26. C.R. Mackay Chemokines: immunology's high impact factors Nat. Immunol. 2 2001 95 101
27. Y. Matsuo, H. Onodera, Y. Shiga, M. Nakamura, M. Ninomiya, T. Kihara, and K. Kogure Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat. Effects of neutrophil depletion Stroke 25 1994 1469 1475
28. O. Petrault, T. Ouk, S. Gautier, M. Laprais, P. Gele, M. Bastide, and R. Bordet Pharmacological neutropenia prevents endothelial dysfunction but not smooth muscle functions impairment induced by middle cerebral artery occlusion Br. J. Pharmacol. 144 2005 1051 1058
29. B.K. Popivanova, K. Koike, A.B. Tonchev, Y. Ishida, T. Kondo, S. Ogawa, N. Mukaida, M. Inoue, and T. Yamashima Accumulation of microglial cells expressing ELR motif-positive CXC chemokines and their receptor CXCR2 in monkey hippocampus after ischemia-reperfusion Brain Res. 970 2003 195 204
30. C. Puma, M. Danik, R. Quirion, F. Ramon, and S. Williams The chemokine interleukin-8 acutely reduces Ca(2+) currents in identified cholinergic septal neurons expressing CXCR1 and CXCR2 receptor mRNAs J. Neurochem. 78 2001 960 971
31. B.J. Rollins Chemokines Blood 90 1997 909 928
32. D. Rossi, and A. Zlotnik The biology of chemokines and their receptors Annu. Rev. Immunol. 18 2000 217 242
33. J.M. Schwab, T.D. Nguyen, R. Meyermann, and H.J. Schluesener Human focal cerebral infarctions induce differential lesional interleukin-16 (IL-16) expression confined to infiltrating granulocytes, CD8+ T-lymphocytes and activated microglia/macrophages J. Neuroimmunol. 114 2001 232 241
34. B.D. Semple, T. Kossmann, and M.C. Morganti-Kossmann Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks J. Cereb. Blood Flow Metab. 30 2010 459 473
35. S.L. Stevens, J. Bao, J. Hollis, N.S. Lessov, W.M. Clark, and M.P. Stenzel-Poore The use of flow cytometry to evaluate temporal changes in inflammatory cells following focal cerebral ischemia in mice Brain Res. 932 2002 110 119
36. R.M. Strieter, T.J. Standiford, G.B. Huffnagle, L.M. Colletti, N.W. Lukacs, and S.L. Kunkel The good, the bad, and the ugly. The role of chemokines in models of human disease J. Immunol. 156 1996 3583 3586
37. M. Tani, M.E. Fuentes, J.W. Peterson, B.D. Trapp, S.K. Durham, J.K. Loy, R. Bravo, R.M. Ransohoff, and S.A. Lira Neutrophil infiltration, glial reaction, and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes J. Clin. Invest. 98 1996 529 539
38. E. Tarkowski, L. Rosengren, C. Blomstrand, C. Wikkelso, C. Jensen, S. Ekholm, and A. Tarkowski Intrathecal release of pro- and anti-inflammatory cytokines during stroke Clin. Exp. Immunol. 110 1997 492 499
39. A. Valles, L. Grijpink-Ongering, F.M. de Bree, T. Tuinstra, and E. Ronken Differential regulation of the CXCR2 chemokine network in rat brain trauma: implications for neuroimmune interactions and neuronal survival Neurobiol. Dis. 22 2006 312 322
40. X. Wang, L. Xu, H. Wang, Y. Zhan, E. Pure, and G.Z. Feuerstein CD44 deficiency in mice protects brain from cerebral ischemia injury J. Neurochem. 83 2002 1172 1179
41. J.R. White, J.M. Lee, P.R. Young, R.P. Hertzberg, A.J. Jurewicz, M.A. Chaikin, K. Widdowson, J.J. Foley, L.D. Martin, D.E. Griswold, and H.M. Sarau Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration J. Biol. Chem. 273 1998 10095 10098
42. Y. Yamasaki, Y. Matsuo, N. Matsuura, H. Onodera, Y. Itoyama, and K. Kogure Transient increase of cytokine-induced neutrophil chemoattractant, a member of the interleukin-8 family, in ischemic brain areas after focal ischemia in rats Stroke 26 1995 318 322 discussion 322-3
43. G. Yilmaz, T.V. Arumugam, K.Y. Stokes, and D.N. Granger Role of T lymphocytes and interferon-gamma in ischemic stroke Circulation 113 2006 2105 2112
44. A. Zlotnik, and O. Yoshie Chemokines: a new classification system and their role in immunity Immunity 12 2000 121 127