An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting

Nucleic Acids Research

Volumn 44, Issue 19, 2016, Pages

  Cao, Jian ^a   Wu, Lizhen ^a   Zhang, Shang Min ^a   Lu, Min ^a,b   Cheung, William K C ^a   Cai, Wesley ^a   Gale, Molly ^a   Xu, Qi ^a,c   Yan, Qin ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARBIN INSTITUTE OF TECHNOLOGY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; LYSINE DEMETHYLASE 5A; LYSINE DEMETHYLASE 5B; LYSINE DEMETHYLASE 5C; METHYLTRANSFERASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CAS9 ENDONUCLEASE STREPTOCOCCUS PYOGENES; CRISPR ASSOCIATED ENDONUCLEASE CAS9; CRISPR-CAS SYSTEM GUIDE RNA; ENDONUCLEASE; RETINOBLASTOMA BINDING PROTEIN 2;

ARTICLE; CONTROLLED STUDY; CRISPR CAS SYSTEM; EXPRESSION VECTOR; GENE DISRUPTION; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC PROCEDURES; GENOME EDITING; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR CLONING; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; CELL LINE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENE KNOCKOUT; GENE ORDER; GENE VECTOR; GENETICS; HUMAN; METABOLISM; PROCEDURES; PROMOTER REGION; REPORTER GENE;

BACTERIAL PROTEINS; CELL LINE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEIN 9; CRISPR-CAS SYSTEMS; ENDONUCLEASES; GENE EXPRESSION; GENE KNOCKOUT TECHNIQUES; GENE ORDER; GENE SILENCING; GENE TARGETING; GENES, REPORTER; GENETIC VECTORS; HUMANS; PROMOTER REGIONS, GENETIC; RETINOBLASTOMA-BINDING PROTEIN 2; RNA, GUIDE, CRISPR-CAS SYSTEMS;

EID: 84994888055     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw660     Document Type: Article

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