Engineering Human Stem Cell Lines with Inducible Gene Knockout using CRISPR/Cas9

Cell Stem Cell

Volumn 17, Issue 2, 2015, Pages 233-244

  Chen, Yuejun ^a   Cao, Jingyuan ^a   Xiong, Man ^a,b   Petersen, Andrew J ^a   Dong, Yi ^a   Tao, Yunlong ^a   Huang, Cindy Tzu Ling ^a   Du, Zhongwei ^a   Zhang, Su Chun ^a,c,d  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b FUDAN UNIVERSITY   (China)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE 2 PROTEIN; TRANSCRIPTION FACTOR OTX2; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX2; GUIDE RNA; OTX2 PROTEIN, HUMAN; PHOSPHOLIPID TRANSFER PROTEIN; TRANSCRIPTION FACTOR OTX;

ARTICLE; CELL DIFFERENTIATION; CELL ENGINEERING; CONTROLLED STUDY; CRISPR CAS SYSTEM; CRISPR CAS9 SYSTEM; EMBRYONIC STEM CELL; EXON; GENE CASSETTE; GENE EXPRESSION; GENE INACTIVATION; GENE INSERTION; GENE TARGETING; GENETIC RESISTANCE; HUMAN; HUMAN CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; STEM CELL LINE; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GENETICS; HOMOZYGOTE; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES; STEM CELL;

BASE SEQUENCE; CELL DIFFERENTIATION; CRISPR-CAS SYSTEMS; EXONS; GENE EXPRESSION REGULATION; GENE KNOCK-IN TECHNIQUES; GENE KNOCKOUT TECHNIQUES; GENE TARGETING; GENETIC ENGINEERING; HOMOZYGOTE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; OTX TRANSCRIPTION FACTORS; PHOSPHOLIPID TRANSFER PROTEINS; PLURIPOTENT STEM CELLS; RNA, GUIDE; STEM CELLS;

EID: 84938746868     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2015.06.001     Document Type: Article

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