메뉴 건너뛰기




Volumn 95, Issue 6, 2017, Pages 1242-1256

Animal models of chronic pain: Advances and challenges for clinical translation

Author keywords

animal models; chronic pain; pain

Indexed keywords

ANIMAL MODEL; ARTHRITIS; CHRONIC INFLAMMATORY PAIN; CHRONIC PAIN; DYSFUNCTIONAL PAIN; NEUROPATHIC PAIN; NONHUMAN; PAIN ASSESSMENT; PREDICTIVE VALIDITY; PRIORITY JOURNAL; PSYCHOGENIC PAIN; REVIEW; VISCERAL PAIN; ANIMAL; DISEASE MODEL; PRECLINICAL STUDY;

EID: 84994218605     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23768     Document Type: Review
Times cited : (139)

References (220)
  • 3
    • 33750615070 scopus 로고    scopus 로고
    • Incidence and prevalence of rheumatoid arthritis, based on the 1987 American College of Rheumatology criteria: a systematic review
    • Alamanos Y, Voulgari PV, Drosos AA. 2006. Incidence and prevalence of rheumatoid arthritis, based on the 1987 American College of Rheumatology criteria: a systematic review. Semin Arthritis Rheum 36:182–188.
    • (2006) Semin Arthritis Rheum , vol.36 , pp. 182-188
    • Alamanos, Y.1    Voulgari, P.V.2    Drosos, A.A.3
  • 4
    • 84938904727 scopus 로고    scopus 로고
    • Knee osteoarthritis related pain: a narrative review of diagnosis and treatment
    • Alshami AM. 2014. Knee osteoarthritis related pain: a narrative review of diagnosis and treatment. Int J Health Sci 8:85–104.
    • (2014) Int J Health Sci , vol.8 , pp. 85-104
    • Alshami, A.M.1
  • 5
    • 0022975114 scopus 로고
    • Stress-induced analgesia: adaptive pain suppression
    • Amit Z, Galina ZH. 1986. Stress-induced analgesia: adaptive pain suppression. Physiol Rev 66:1091–1120.
    • (1986) Physiol Rev , vol.66 , pp. 1091-1120
    • Amit, Z.1    Galina, Z.H.2
  • 7
    • 84941247747 scopus 로고    scopus 로고
    • Repeated mu-opioid exposure induces a novel form of the hyperalgesic priming model for transition to chronic pain
    • Araldi D, Ferrari LF, Levine JD. 2015. Repeated mu-opioid exposure induces a novel form of the hyperalgesic priming model for transition to chronic pain. J Neurosci 35:12502–12517.
    • (2015) J Neurosci , vol.35 , pp. 12502-12517
    • Araldi, D.1    Ferrari, L.F.2    Levine, J.D.3
  • 8
    • 84962114163 scopus 로고    scopus 로고
    • Adenosine-A1 receptor agonist induced hyperalgesic priming type II
    • Araldi D, Ferrari LF, Levine JD. 2016a. Adenosine-A1 receptor agonist induced hyperalgesic priming type II. Pain 157:698–709.
    • (2016) Pain , vol.157 , pp. 698-709
    • Araldi, D.1    Ferrari, L.F.2    Levine, J.D.3
  • 9
    • 84979696898 scopus 로고    scopus 로고
    • Gi-protein coupled 5-HT1B/D receptor agonist sumatriptan induces type i hyperalgesic priming
    • Araldi D, Ferrari LF, Levine JD. 2016b. Gi-protein coupled 5-HT1B/D receptor agonist sumatriptan induces type i hyperalgesic priming. Pain 157:1773–1782.
    • (2016) Pain , vol.157 , pp. 1773-1782
    • Araldi, D.1    Ferrari, L.F.2    Levine, J.D.3
  • 11
    • 38049028807 scopus 로고    scopus 로고
    • Cannabinoids for the treatment of neuropathic pain: clinical evidence
    • Ashton JC, Milligan ED. 2008. Cannabinoids for the treatment of neuropathic pain: clinical evidence. Curr Opin Invest Drugs 9:65–75.
    • (2008) Curr Opin Invest Drugs , vol.9 , pp. 65-75
    • Ashton, J.C.1    Milligan, E.D.2
  • 13
    • 5644220419 scopus 로고    scopus 로고
    • Neuropathic pain symptoms relative to overall pain rating
    • Backonja M-M, Stacey B. 2004. Neuropathic pain symptoms relative to overall pain rating. J Pain 5:491–497.
    • (2004) J Pain , vol.5 , pp. 491-497
    • Backonja, M.-M.1    Stacey, B.2
  • 15
    • 84907450500 scopus 로고    scopus 로고
    • Functional reorganization of the default mode network across chronic pain conditions
    • Baliki MN, Mansour AR, Baria AT, Apkarian AV. 2014. Functional reorganization of the default mode network across chronic pain conditions. PLoS One 9:e106133.
    • (2014) PLoS One , vol.9
    • Baliki, M.N.1    Mansour, A.R.2    Baria, A.T.3    Apkarian, A.V.4
  • 17
    • 0023895875 scopus 로고
    • A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
    • Bennett GJ, Xie YK. 1988. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 3:87–107.
    • (1988) Pain , vol.3 , pp. 87-107
    • Bennett, G.J.1    Xie, Y.K.2
  • 18
    • 80053337076 scopus 로고    scopus 로고
    • Predictive validity of behavioural animal models for chronic pain
    • Berge O-G. 2011. Predictive validity of behavioural animal models for chronic pain. Br J Pharmacol 16:1195–1206.
    • (2011) Br J Pharmacol , vol.16 , pp. 1195-1206
    • Berge, O.-G.1
  • 19
    • 0034433476 scopus 로고    scopus 로고
    • Neurobehavioral protection by the neuronal calcium channel blocker ziconotide in a model of traumatic diffuse brain injury in rats
    • Berman RF, Verweij BH, Muizelaar JP. 2000. Neurobehavioral protection by the neuronal calcium channel blocker ziconotide in a model of traumatic diffuse brain injury in rats. J Neurosurg 93:821–828.
    • (2000) J Neurosurg , vol.93 , pp. 821-828
    • Berman, R.F.1    Verweij, B.H.2    Muizelaar, J.P.3
  • 20
    • 0034076537 scopus 로고    scopus 로고
    • Physiological properties of the lamina I spinoparabrachial neurons in the rat
    • Bester H, Chapman V, Besson JM, Bernard JF. 2000. Physiological properties of the lamina I spinoparabrachial neurons in the rat. J Neurophysiol 83:2239–2259.
    • (2000) J Neurophysiol , vol.83 , pp. 2239-2259
    • Bester, H.1    Chapman, V.2    Besson, J.M.3    Bernard, J.F.4
  • 21
    • 84875410203 scopus 로고    scopus 로고
    • Current interventions in the management of knee osteoarthritis
    • Bhatia D, Bejarano T, Novo M. 2013. Current interventions in the management of knee osteoarthritis. J Pharm Bioallied Sci 5:30–38.
    • (2013) J Pharm Bioallied Sci , vol.5 , pp. 30-38
    • Bhatia, D.1    Bejarano, T.2    Novo, M.3
  • 22
    • 29844435136 scopus 로고    scopus 로고
    • Preliminary assessment of the efficacy, tolerability, and safety of a cannabis-based medicine (sativex) in the treatment of pain caused by rheumatoid arthritis
    • Blake DR, Robson P, Ho M, Jubb RW, McCabe CS. 2006. Preliminary assessment of the efficacy, tolerability, and safety of a cannabis-based medicine (sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology 45:50–52.
    • (2006) Rheumatology , vol.45 , pp. 50-52
    • Blake, D.R.1    Robson, P.2    Ho, M.3    Jubb, R.W.4    McCabe, C.S.5
  • 23
    • 0024161140 scopus 로고
    • Organismic variables and pain inhibition: roles of gender and aging
    • Bodnar RJ, Romero MT, Kramer E. 1988. Organismic variables and pain inhibition: roles of gender and aging. Brain Res Bull 21:947–953.
    • (1988) Brain Res Bull , vol.21 , pp. 947-953
    • Bodnar, R.J.1    Romero, M.T.2    Kramer, E.3
  • 24
    • 77953110410 scopus 로고    scopus 로고
    • Noxious heat threshold measured with slowly increasing temperatures: novel rat thermal hyperalgesia models
    • Bölcskei K, Petho G, Szolcsányi J. 2010. Noxious heat threshold measured with slowly increasing temperatures: novel rat thermal hyperalgesia models. Methods Mol Biol 617:57–66.
    • (2010) Methods Mol Biol , vol.617 , pp. 57-66
    • Bölcskei, K.1    Petho, G.2    Szolcsányi, J.3
  • 25
    • 43549106321 scopus 로고    scopus 로고
    • Prevalence of chronic pain with neuropathic characteristics in the general population
    • Bouhassira D, Lantéri-Minet M, Attal N, Laurent B, Touboul C. 2008. Prevalence of chronic pain with neuropathic characteristics in the general population. Pain 136:380–387.
    • (2008) Pain , vol.136 , pp. 380-387
    • Bouhassira, D.1    Lantéri-Minet, M.2    Attal, N.3    Laurent, B.4    Touboul, C.5
  • 27
    • 0242606943 scopus 로고    scopus 로고
    • Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis
    • Bove SE, Calcaterra SL, Brooker RM, Huber CM, Guzman RE, Juneau PL, Schrier DJ, Kilgore KS. 2003. Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis. Osteoarthritis Cartilage 11:821–830.
    • (2003) Osteoarthritis Cartilage , vol.11 , pp. 821-830
    • Bove, S.E.1    Calcaterra, S.L.2    Brooker, R.M.3    Huber, C.M.4    Guzman, R.E.5    Juneau, P.L.6    Schrier, D.J.7    Kilgore, K.S.8
  • 28
    • 0033966262 scopus 로고    scopus 로고
    • Sex differences and phases of the estrous cycle alter the response of spinal cord dynorphin neurons to peripheral inflammation and hyperalgesia
    • Bradshaw H, Miller J, Ling Q, Malsnee K, Ruda MA. 2000. Sex differences and phases of the estrous cycle alter the response of spinal cord dynorphin neurons to peripheral inflammation and hyperalgesia. Pain 85:93–99.
    • (2000) Pain , vol.85 , pp. 93-99
    • Bradshaw, H.1    Miller, J.2    Ling, Q.3    Malsnee, K.4    Ruda, M.A.5
  • 29
    • 0345056205 scopus 로고    scopus 로고
    • Postoperative models of nociception
    • Brennan TJ. 1999. Postoperative models of nociception. ILAR J 40:129–136.
    • (1999) ILAR J , vol.40 , pp. 129-136
    • Brennan, T.J.1
  • 31
    • 67349120237 scopus 로고    scopus 로고
    • Stress-induced analgesia
    • Butler RK, Finn DP. 2009. Stress-induced analgesia. Prog Neurobiol 88:184–202.
    • (2009) Prog Neurobiol , vol.88 , pp. 184-202
    • Butler, R.K.1    Finn, D.P.2
  • 32
    • 49849098780 scopus 로고    scopus 로고
    • A new knee surgery model in rats to evaluate functional measures of postoperative pain
    • Buvanendran A, Kroin JS, Kari MR, Tuman KJ. 2008. A new knee surgery model in rats to evaluate functional measures of postoperative pain. Anesth Analg 107:300–308.
    • (2008) Anesth Analg , vol.107 , pp. 300-308
    • Buvanendran, A.1    Kroin, J.S.2    Kari, M.R.3    Tuman, K.J.4
  • 33
    • 77953102747 scopus 로고    scopus 로고
    • Alternatives to mammalian pain models 2: using Drosophila to identify novel genes involved in nociception
    • Caldwell JC, Tracey WD. 2010. Alternatives to mammalian pain models 2: using Drosophila to identify novel genes involved in nociception. Methods Mol Biol 617:19–29.
    • (2010) Methods Mol Biol , vol.617 , pp. 19-29
    • Caldwell, J.C.1    Tracey, W.D.2
  • 34
    • 4043055159 scopus 로고    scopus 로고
    • The good and the bad effects of (–)trans-delta-9-tetrahydrocannabinol (delta-9-THC) on humans
    • Carlini EA. 2004. The good and the bad effects of (–)trans-delta-9-tetrahydrocannabinol (delta-9-THC) on humans. Toxicon 44:461–467.
    • (2004) Toxicon , vol.44 , pp. 461-467
    • Carlini, E.A.1
  • 35
    • 70449622719 scopus 로고    scopus 로고
    • Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury
    • Carlton SM, Du J, Tan HY, Nesic O, Hargett GL, Bopp AC, Yamani A, Lin Q, Willis WD, Hulsebosch CE. 2009. Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury. Pain 147:265–276.
    • (2009) Pain , vol.147 , pp. 265-276
    • Carlton, S.M.1    Du, J.2    Tan, H.Y.3    Nesic, O.4    Hargett, G.L.5    Bopp, A.C.6    Yamani, A.7    Lin, Q.8    Willis, W.D.9    Hulsebosch, C.E.10
  • 36
    • 0033652138 scopus 로고    scopus 로고
    • Dextromethorphan, an NMDA-receptor antagonist, enhances the analgesic properties of morphine
    • Caruso FS, Goldblum R, Group TMS. 2000. Dextromethorphan, an NMDA-receptor antagonist, enhances the analgesic properties of morphine. Inflammopharmacology 8:161–173.
    • (2000) Inflammopharmacology , vol.8 , pp. 161-173
    • Caruso, F.S.1    Goldblum, R.2    Group, T.M.S.3
  • 37
    • 84887296146 scopus 로고    scopus 로고
    • Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation—United States, 2010–2012
    • Centers for Disease Control and Prevention. 2013. Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation—United States, 2010–2012. MMWR Morbid Mortal Wkly Rep 62:869–873.
    • (2013) MMWR Morbid Mortal Wkly Rep , vol.62 , pp. 869-873
  • 38
    • 0029076498 scopus 로고
    • Visceral pain: mechanisms of peripheral and central sensitization
    • Cervero F. 1995. Visceral pain: mechanisms of peripheral and central sensitization. Ann Med 27:235–239.
    • (1995) Ann Med , vol.27 , pp. 235-239
    • Cervero, F.1
  • 39
    • 0029671403 scopus 로고    scopus 로고
    • The effect of age on A delta- and C-fibre thermal pain perception
    • Chakour MC, Gibson SJ, Bradbeer M, Helme RD. 1996. The effect of age on A delta- and C-fibre thermal pain perception. Pain 64:143–152.
    • (1996) Pain , vol.64 , pp. 143-152
    • Chakour, M.C.1    Gibson, S.J.2    Bradbeer, M.3    Helme, R.D.4
  • 40
    • 84924227883 scopus 로고    scopus 로고
    • Surgical animal models of neuropathic pain: pros and cons
    • Challa SR. 2015. Surgical animal models of neuropathic pain: pros and cons. Int J Neurosci 125:170–174.
    • (2015) Int J Neurosci , vol.125 , pp. 170-174
    • Challa, S.R.1
  • 41
    • 0028335910 scopus 로고
    • Role of voltage-dependent calcium channel subtypes in experimental tactile allodynia
    • Chaplan SR, Pogrel JW, Yaksh TL. 1994. Role of voltage-dependent calcium channel subtypes in experimental tactile allodynia. J Pharmacol Exp Ther 269:1117–1123.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 1117-1123
    • Chaplan, S.R.1    Pogrel, J.W.2    Yaksh, T.L.3
  • 42
    • 84858701250 scopus 로고    scopus 로고
    • Inflammation-induced decrease in voluntary wheel running in mice: a nonreflexive test for evaluating inflammatory pain and analgesia
    • Cobos EJ, Ghasemlou N, Araldi D, Segal D, Duong K, Woolf CJ. 2012. Inflammation-induced decrease in voluntary wheel running in mice: a nonreflexive test for evaluating inflammatory pain and analgesia. Pain 153:876–884.
    • (2012) Pain , vol.153 , pp. 876-884
    • Cobos, E.J.1    Ghasemlou, N.2    Araldi, D.3    Segal, D.4    Duong, K.5    Woolf, C.J.6
  • 43
    • 84898612016 scopus 로고    scopus 로고
    • Development of the horse grimace scale (HGS) as a pain assessment tool in horses undergoing routine castration
    • Costa ED, Minero M, Lebelt D, Stucke D, Canali E, Leach MC. 2014. Development of the horse grimace scale (HGS) as a pain assessment tool in horses undergoing routine castration. PLoS One 9:e92281.
    • (2014) PLoS One , vol.9
    • Costa, E.D.1    Minero, M.2    Lebelt, D.3    Stucke, D.4    Canali, E.5    Leach, M.C.6
  • 47
    • 0025799429 scopus 로고
    • Genuine, suppressed, and faked facial behavior during exacerbation of chronic low back pain
    • Craig KD, Hyde SA, Patrick CJ. 1991. Genuine, suppressed, and faked facial behavior during exacerbation of chronic low back pain. Pain 46:161–171.
    • (1991) Pain , vol.46 , pp. 161-171
    • Craig, K.D.1    Hyde, S.A.2    Patrick, C.J.3
  • 48
    • 0002261078 scopus 로고
    • A method for determining loss of pain sensation
    • D'Amour FE, Smith DL. 1941. A method for determining loss of pain sensation. J Pharmacol Exp Ther 72:74–79.
    • (1941) J Pharmacol Exp Ther , vol.72 , pp. 74-79
    • D'Amour, F.E.1    Smith, D.L.2
  • 49
    • 79961209828 scopus 로고    scopus 로고
    • Conditioned place preference reveals tonic pain in an animal model of central pain
    • Davoody L, Quiton RL, Lucas JM, Ji Y, Keller A, Masri R. 2011. Conditioned place preference reveals tonic pain in an animal model of central pain. J Pain 12:868–874.
    • (2011) J Pain , vol.12 , pp. 868-874
    • Davoody, L.1    Quiton, R.L.2    Lucas, J.M.3    Ji, Y.4    Keller, A.5    Masri, R.6
  • 50
    • 0032981204 scopus 로고    scopus 로고
    • Pharmacological aspects of experimental headache models in relation to acute antimigraine therapy
    • De Vries P, Villalón CM, Saxena PR. 1999. Pharmacological aspects of experimental headache models in relation to acute antimigraine therapy. Eur J Pharmacol 375:61–74.
    • (1999) Eur J Pharmacol , vol.375 , pp. 61-74
    • De Vries, P.1    Villalón, C.M.2    Saxena, P.R.3
  • 51
    • 0034255439 scopus 로고    scopus 로고
    • Spared nerve injury: an animal model of persistent peripheral neuropathic pain
    • Decosterd I, Woolf CJ. 2000. Spared nerve injury: an animal model of persistent peripheral neuropathic pain. Pain 87:149–158.
    • (2000) Pain , vol.87 , pp. 149-158
    • Decosterd, I.1    Woolf, C.J.2
  • 53
    • 0031043244 scopus 로고    scopus 로고
    • Blockade of spinal N- and P-type, but not L-type, calcium channels inhibits the excitability of rat dorsal horn neurones produced by subcutaneous formalin inflammation
    • Diaz A, Dickenson AH. 1997. Blockade of spinal N- and P-type, but not L-type, calcium channels inhibits the excitability of rat dorsal horn neurones produced by subcutaneous formalin inflammation. Pain 69:93–100.
    • (1997) Pain , vol.69 , pp. 93-100
    • Diaz, A.1    Dickenson, A.H.2
  • 54
    • 84927573799 scopus 로고    scopus 로고
    • Neuropathic pain in osteoarthritis: a review of pathophysiological mechanisms and implications for treatment
    • Dimitroulas T, Duarte RV, Behura A, Kitas GD, Raphael JH. 2014. Neuropathic pain in osteoarthritis: a review of pathophysiological mechanisms and implications for treatment. Semin Arthritis Rheum 44:145–154.
    • (2014) Semin Arthritis Rheum , vol.44 , pp. 145-154
    • Dimitroulas, T.1    Duarte, R.V.2    Behura, A.3    Kitas, G.D.4    Raphael, J.H.5
  • 55
  • 56
    • 78049420335 scopus 로고    scopus 로고
    • Nociceptors: the sensors of the pain pathway
    • Dubin AE, Patapoutian A. 2010. Nociceptors: the sensors of the pain pathway. J Clin Invest 120:3760–3772.
    • (2010) J Clin Invest , vol.120 , pp. 3760-3772
    • Dubin, A.E.1    Patapoutian, A.2
  • 59
    • 84903726760 scopus 로고    scopus 로고
    • Mouse models of osteoarthritis: modelling risk factors and assessing outcomes
    • Fang H, Beier F. 2014. Mouse models of osteoarthritis: modelling risk factors and assessing outcomes. Nat Rev Rheumatol 10:413–421.
    • (2014) Nat Rev Rheumatol , vol.10 , pp. 413-421
    • Fang, H.1    Beier, F.2
  • 60
    • 84896820721 scopus 로고    scopus 로고
    • Second messengers mediating the expression of neuroplasticity in a model of chronic pain in the rat
    • Ferrari LF, Bogen O, Levine JD. 2014. Second messengers mediating the expression of neuroplasticity in a model of chronic pain in the rat. J Pain 15:312–320.
    • (2014) J Pain , vol.15 , pp. 312-320
    • Ferrari, L.F.1    Bogen, O.2    Levine, J.D.3
  • 61
    • 84920997584 scopus 로고    scopus 로고
    • Accounting for the delay in the transition from acute to chronic pain: axonal and nuclear mechanisms
    • Ferrari LF, Bogen O, Reichling DB, Levine JD. 2015. Accounting for the delay in the transition from acute to chronic pain: axonal and nuclear mechanisms. J Neurosci 35:495–507.
    • (2015) J Neurosci , vol.35 , pp. 495-507
    • Ferrari, L.F.1    Bogen, O.2    Reichling, D.B.3    Levine, J.D.4
  • 64
    • 0033000028 scopus 로고    scopus 로고
    • Critical evaluation of the streptozotocin model of painful diabetic neuropathy in the rat
    • Fox A, Eastwood C, Gentry C, Manning D, Urban L. 1999. Critical evaluation of the streptozotocin model of painful diabetic neuropathy in the rat. Pain 81:307–316.
    • (1999) Pain , vol.81 , pp. 307-316
    • Fox, A.1    Eastwood, C.2    Gentry, C.3    Manning, D.4    Urban, L.5
  • 67
    • 0027238266 scopus 로고
    • Diet and estrous cycle influence pain sensitivity in rats
    • Frye CA, Cuevas CA, Kanarek RB. 1993. Diet and estrous cycle influence pain sensitivity in rats. Pharmacol Biochem Behav 45:255–260.
    • (1993) Pharmacol Biochem Behav , vol.45 , pp. 255-260
    • Frye, C.A.1    Cuevas, C.A.2    Kanarek, R.B.3
  • 68
    • 84858650647 scopus 로고    scopus 로고
    • The place escape/avoidance paradigm: a novel method to assess nociceptive processing
    • Fuchs PN, McNabb CT. 2012. The place escape/avoidance paradigm: a novel method to assess nociceptive processing. J Integr Neurosci 11:61–72.
    • (2012) J Integr Neurosci , vol.11 , pp. 61-72
    • Fuchs, P.N.1    McNabb, C.T.2
  • 69
    • 0031772025 scopus 로고    scopus 로고
    • Aspects on tail-flick, hot-plate, and electrical stimulation tests for morphine antinociception
    • Gårdmark M, Höglund AU, Hammarlund-Udenaes M. 1998. Aspects on tail-flick, hot-plate, and electrical stimulation tests for morphine antinociception. Pharmacol Toxicol 83:252–258.
    • (1998) Pharmacol Toxicol , vol.83 , pp. 252-258
    • Gårdmark, M.1    Höglund, A.U.2    Hammarlund-Udenaes, M.3
  • 70
    • 85017055958 scopus 로고    scopus 로고
    • Available online at
    • Global Industry Analysts, Inc. 2011. Available online at http://www.prweb.com/pdfdownload/8052240.pdf
    • (2011)
  • 71
    • 80053510653 scopus 로고    scopus 로고
    • Pain as a global public health priority
    • Goldberg DS, McGee SJ. 2011. Pain as a global public health priority. BMC Public Health 11:770.
    • (2011) BMC Public Health , vol.11 , pp. 770
    • Goldberg, D.S.1    McGee, S.J.2
  • 72
    • 77649226018 scopus 로고    scopus 로고
    • The zebrafish: a model to study the endogenous mechanisms of pain
    • Gonzalez-Nunez V, Rodríguez RE. 2009. The zebrafish: a model to study the endogenous mechanisms of pain. ILAR J 50:373–386.
    • (2009) ILAR J , vol.50 , pp. 373-386
    • Gonzalez-Nunez, V.1    Rodríguez, R.E.2
  • 74
    • 0036676984 scopus 로고    scopus 로고
    • Peripheral and central sensitization in musculoskeletal pain disorders: an experimental approach
    • Graven-Nielsen T, Arendt-Nielsen L. 2002. Peripheral and central sensitization in musculoskeletal pain disorders: an experimental approach. Curr Rheumatol Rep 4:313–321.
    • (2002) Curr Rheumatol Rep , vol.4 , pp. 313-321
    • Graven-Nielsen, T.1    Arendt-Nielsen, L.2
  • 75
    • 0242552331 scopus 로고    scopus 로고
    • Monoiodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis
    • Guzman RE, Evans MG, Bove S, Morenko B, Kilgore K. 2003. Monoiodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis. Toxicol Pathol 31:619–624.
    • (2003) Toxicol Pathol , vol.31 , pp. 619-624
    • Guzman, R.E.1    Evans, M.G.2    Bove, S.3    Morenko, B.4    Kilgore, K.5
  • 76
    • 77957927869 scopus 로고    scopus 로고
    • Animal models of central neuropathic pain
    • In, Ma C, Zhang J-M, editors., New York, Humana Press, p
    • Hains B, Vera-Portocarrero L. 2011. Animal models of central neuropathic pain. In: Ma C, Zhang J-M, editors. Animal models of pain. New York: Humana Press. p 103–115.
    • (2011) Animal models of pain , pp. 103-115
    • Hains, B.1    Vera-Portocarrero, L.2
  • 77
    • 0037402382 scopus 로고    scopus 로고
    • Unmet needs in the management of neuropathic pain
    • Harden N, Cohen M. 2003. Unmet needs in the management of neuropathic pain. J Pain Sympt Manag 25:S12–S17.
    • (2003) J Pain Sympt Manag , vol.25 , pp. S12-S17
    • Harden, N.1    Cohen, M.2
  • 78
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves K, Dubner R, Brown F, Flores C, Joris J. 1988. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77–88.
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 79
    • 0036213896 scopus 로고    scopus 로고
    • Analgesic effects of dextromethorphan and morphine in patients with chronic pain
    • Heiskanen T, Härtel B, Dahl M-L, Seppälä T, Kalso E. 2002. Analgesic effects of dextromethorphan and morphine in patients with chronic pain. Pain 96:261–267.
    • (2002) Pain , vol.96 , pp. 261-267
    • Heiskanen, T.1    Härtel, B.2    Dahl, M.-L.3    Seppälä, T.4    Kalso, E.5
  • 80
    • 0034214841 scopus 로고    scopus 로고
    • NK1 (substance P) receptor antagonists—why are they not analgesic in humans?
    • Hill R. 2000. NK1 (substance P) receptor antagonists—why are they not analgesic in humans? Trends Pharmacol Sci 21:244–246.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 244-246
    • Hill, R.1
  • 82
    • 0034130227 scopus 로고    scopus 로고
    • Murine models of inflammatory, neuropathic, and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons
    • Honore P, Rogers SD, Schwei MJ, Salak-Johnson JL, Luger NM, Sabino MC, Clohisy DR, Mantyh PW. 2000. Murine models of inflammatory, neuropathic, and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons. Neuroscience 98:585–598.
    • (2000) Neuroscience , vol.98 , pp. 585-598
    • Honore, P.1    Rogers, S.D.2    Schwei, M.J.3    Salak-Johnson, J.L.4    Luger, N.M.5    Sabino, M.C.6    Clohisy, D.R.7    Mantyh, P.W.8
  • 83
    • 0031452427 scopus 로고    scopus 로고
    • Dorsal column lesions reverse the reduction of homecage activity in rats with pancreatitis
    • Houghton AK, Kadura S, Westlund KN. 1997. Dorsal column lesions reverse the reduction of homecage activity in rats with pancreatitis. Neuroreport 8:3795–3800.
    • (1997) Neuroreport , vol.8 , pp. 3795-3800
    • Houghton, A.K.1    Kadura, S.2    Westlund, K.N.3
  • 84
    • 0030801001 scopus 로고    scopus 로고
    • Characterization of heat–hyperalgesia in an experimental trigeminal neuropathy in rats
    • Imamura Y, Kawamoto H, Nakanishi O. 1997. Characterization of heat–hyperalgesia in an experimental trigeminal neuropathy in rats. Exp Brain Res 116:97–103.
    • (1997) Exp Brain Res , vol.116 , pp. 97-103
    • Imamura, Y.1    Kawamoto, H.2    Nakanishi, O.3
  • 86
    • 84906076303 scopus 로고    scopus 로고
    • Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms
    • Jensen TS, Finnerup NB. 2014. Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms. Lancet Neurol 13:924–935.
    • (2014) Lancet Neurol , vol.13 , pp. 924-935
    • Jensen, T.S.1    Finnerup, N.B.2
  • 87
    • 84903814786 scopus 로고    scopus 로고
    • Emerging targets in neuroinflammation-driven chronic pain
    • Ji R-R, Xu Z-Z, Gao Y-J. 2014. Emerging targets in neuroinflammation-driven chronic pain. Nat Rev Drug Discov 13:533–548.
    • (2014) Nat Rev Drug Discov , vol.13 , pp. 533-548
    • Ji, R.-R.1    Xu, Z.-Z.2    Gao, Y.-J.3
  • 88
    • 0034947242 scopus 로고    scopus 로고
    • The affective component of pain in rodents: direct evidence for a contribution of the anterior cingulate cortex
    • Johansen JP, Fields HL, Manning BH. 2001. The affective component of pain in rodents: direct evidence for a contribution of the anterior cingulate cortex. Proc Natl Acad Sci U S A 98:8077–8082.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 8077-8082
    • Johansen, J.P.1    Fields, H.L.2    Manning, B.H.3
  • 89
    • 0035847651 scopus 로고    scopus 로고
    • The effect of age on pain, function, and quality of life after total hip and knee arthroplasty
    • Jones CA, Voaklander DC, Johnston DW, Suarez-Almazor ME. 2001. The effect of age on pain, function, and quality of life after total hip and knee arthroplasty. Arch Intern Med 161:454–460.
    • (2001) Arch Intern Med , vol.161 , pp. 454-460
    • Jones, C.A.1    Voaklander, D.C.2    Johnston, D.W.3    Suarez-Almazor, M.E.4
  • 90
    • 0346724920 scopus 로고    scopus 로고
    • Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat
    • Joseph EK, Chen X, Khasar SG, Levine JD. 2004. Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat. Pain 107:147–158.
    • (2004) Pain , vol.107 , pp. 147-158
    • Joseph, E.K.1    Chen, X.2    Khasar, S.G.3    Levine, J.D.4
  • 91
    • 77950657123 scopus 로고    scopus 로고
    • Shared mechanisms for opioid tolerance and a transition to chronic pain
    • Joseph EK, Reichling DB, Levine JD. 2010. Shared mechanisms for opioid tolerance and a transition to chronic pain. J Neurosci 30:4660–4666.
    • (2010) J Neurosci , vol.30 , pp. 4660-4666
    • Joseph, E.K.1    Reichling, D.B.2    Levine, J.D.3
  • 92
    • 34948856571 scopus 로고    scopus 로고
    • Postoperative administration of the analgesic tramadol, but not the selective cyclooxygenase-2 inhibitor parecoxib, abolishes postoperative hyperalgesia in a new model of postoperative pain in rats
    • Kamerman P, Koller A, Loram L. 2007. Postoperative administration of the analgesic tramadol, but not the selective cyclooxygenase-2 inhibitor parecoxib, abolishes postoperative hyperalgesia in a new model of postoperative pain in rats. Pharmacology 80:244–248.
    • (2007) Pharmacology , vol.80 , pp. 244-248
    • Kamerman, P.1    Koller, A.2    Loram, L.3
  • 93
    • 84927589122 scopus 로고    scopus 로고
    • The pharmacology of nociceptor priming
    • Kandasamy R, Price TJ. 2015. The pharmacology of nociceptor priming. Hndbk Exp Pharmacol 227:15–37.
    • (2015) Hndbk Exp Pharmacol , vol.227 , pp. 15-37
    • Kandasamy, R.1    Price, T.J.2
  • 95
    • 84866077963 scopus 로고    scopus 로고
    • Evaluation of EMLA cream for preventing pain during tattooing of rabbits: changes in physiological, behavioural, and facial expression responses
    • Keating SCJ, Thomas AA, Flecknell PA, Leach MC. 2012. Evaluation of EMLA cream for preventing pain during tattooing of rabbits: changes in physiological, behavioural, and facial expression responses. PLoS One 7:e44437.
    • (2012) PLoS One , vol.7
    • Keating, S.C.J.1    Thomas, A.A.2    Flecknell, P.A.3    Leach, M.C.4
  • 96
    • 0034176506 scopus 로고    scopus 로고
    • A new animal model for assessing mechanisms and management of muscle hyperalgesia
    • Kehl LJ, Trempe TM, Hargreaves KM. 2000. A new animal model for assessing mechanisms and management of muscle hyperalgesia. Pain 85:333–343.
    • (2000) Pain , vol.85 , pp. 333-343
    • Kehl, L.J.1    Trempe, T.M.2    Hargreaves, K.M.3
  • 97
    • 33646344701 scopus 로고    scopus 로고
    • Persistent postsurgical pain: risk factors and prevention
    • Kehlet H, Jensen TS, Woolf CJ. 2006. Persistent postsurgical pain: risk factors and prevention. Lancet 367:1618–1625.
    • (2006) Lancet , vol.367 , pp. 1618-1625
    • Kehlet, H.1    Jensen, T.S.2    Woolf, C.J.3
  • 98
    • 36549088202 scopus 로고    scopus 로고
    • Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain
    • Keller AF, Beggs S, Salter MW, De Koninck Y. 2007. Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain. Mol Pain 3:27.
    • (2007) Mol Pain , vol.3 , pp. 27
    • Keller, A.F.1    Beggs, S.2    Salter, M.W.3    De Koninck, Y.4
  • 99
    • 0036342296 scopus 로고    scopus 로고
    • Anxiety sensitivity, cognitive biases, and the experience of pain
    • Keogh E, Cochrane M. 2002. Anxiety sensitivity, cognitive biases, and the experience of pain. J Pain 3:320–329.
    • (2002) J Pain , vol.3 , pp. 320-329
    • Keogh, E.1    Cochrane, M.2
  • 100
    • 77953109347 scopus 로고    scopus 로고
    • Animal models of acute surgical pain
    • Kim H, Sung B, Mao J. 2010. Animal models of acute surgical pain. Methods Mol Biol 617:31–39.
    • (2010) Methods Mol Biol , vol.617 , pp. 31-39
    • Kim, H.1    Sung, B.2    Mao, J.3
  • 101
    • 80053468028 scopus 로고    scopus 로고
    • Characterization of a new animal model for evaluation and treatment of back pain due to lumbar facet joint osteoarthritis
    • Kim J-S, Kroin JS, Buvanendran A, Li X, van Wijnen AJ, Tuman KJ, Im H-J. 2011. Characterization of a new animal model for evaluation and treatment of back pain due to lumbar facet joint osteoarthritis. Arthritis Rheum 63:2966–2973.
    • (2011) Arthritis Rheum , vol.63 , pp. 2966-2973
    • Kim, J.-S.1    Kroin, J.S.2    Buvanendran, A.3    Li, X.4    van Wijnen, A.J.5    Tuman, K.J.6    Im, H.-J.7
  • 103
    • 84971216410 scopus 로고    scopus 로고
    • Neuroligin-2 regulates spinal GABAergic plasticity in hyperalgesic priming, a model of the transition from acute to chronic pain
    • Kim J-YV, Megat S, Moy JK, Asiedu MN, Mejia GL, Vagner J, Price TJ. 2016. Neuroligin-2 regulates spinal GABAergic plasticity in hyperalgesic priming, a model of the transition from acute to chronic pain. Pain 157:1314–1324.
    • (2016) Pain , vol.157 , pp. 1314-1324
    • Kim, J.-Y.V.1    Megat, S.2    Moy, J.K.3    Asiedu, M.N.4    Mejia, G.L.5    Vagner, J.6    Price, T.J.7
  • 105
    • 0036821181 scopus 로고    scopus 로고
    • Vocalization responses after spinal administration of bicuculline or strychnine in rats
    • Kontinen VK, Meert TF. 2002. Vocalization responses after spinal administration of bicuculline or strychnine in rats. Neuromodulation 5:221–230.
    • (2002) Neuromodulation , vol.5 , pp. 221-230
    • Kontinen, V.K.1    Meert, T.F.2
  • 109
    • 16844365879 scopus 로고    scopus 로고
    • A novel hot-plate test sensitive to hyperalgesic stimuli and nonopioid analgesics
    • Lavich TR, Cordeiro RSB, Silva PMR, Martins MA. 2005. A novel hot-plate test sensitive to hyperalgesic stimuli and nonopioid analgesics. Braz J Med Biol Res 38:445–451.
    • (2005) Braz J Med Biol Res , vol.38 , pp. 445-451
    • Lavich, T.R.1    Cordeiro, R.S.B.2    Silva, P.M.R.3    Martins, M.A.4
  • 112
    • 0034689154 scopus 로고    scopus 로고
    • An animal model of neuropathic pain employing injury to the sciatic nerve branches
    • Lee BH, Won R, Baik EJ, Lee SH, Moon CH. 2000. An animal model of neuropathic pain employing injury to the sciatic nerve branches. Neuroreport 11:657–661.
    • (2000) Neuroreport , vol.11 , pp. 657-661
    • Lee, B.H.1    Won, R.2    Baik, E.J.3    Lee, S.H.4    Moon, C.H.5
  • 114
    • 0022261308 scopus 로고
    • Exposure to a cat produces opioid analgesia in rats
    • Lester LS, Fanselow MS. 1985. Exposure to a cat produces opioid analgesia in rats. Behav Neurosci 99:756–759.
    • (1985) Behav Neurosci , vol.99 , pp. 756-759
    • Lester, L.S.1    Fanselow, M.S.2
  • 115
    • 43749123236 scopus 로고    scopus 로고
    • Analysis of nociception, sex, and peripheral nerve innervation in the TMEV animal model of multiple sclerosis
    • Lynch JL, Gallus NJ, Ericson ME, Beitz AJ. 2008. Analysis of nociception, sex, and peripheral nerve innervation in the TMEV animal model of multiple sclerosis. Pain 136:293–304.
    • (2008) Pain , vol.136 , pp. 293-304
    • Lynch, J.L.1    Gallus, N.J.2    Ericson, M.E.3    Beitz, A.J.4
  • 116
    • 0347319044 scopus 로고    scopus 로고
    • Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications
    • Mangoni AA, Jackson SHD. 2004. Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Clin Pharmacol 57:6–14.
    • (2004) Br J Clin Pharmacol , vol.57 , pp. 6-14
    • Mangoni, A.A.1    Jackson, S.H.D.2
  • 117
    • 84961371041 scopus 로고    scopus 로고
    • Sex differences in pain: a tale of two immune cells
    • Mapplebeck JCS, Beggs S, Salter MW. 2016. Sex differences in pain: a tale of two immune cells. Pain 157:S2–S6.
    • (2016) Pain , vol.157 , pp. S2-S6
    • Mapplebeck, J.C.S.1    Beggs, S.2    Salter, M.W.3
  • 118
    • 84858134383 scopus 로고    scopus 로고
    • The monosodium iodoacetate model of osteoarthritis pain in the rat
    • Marker CL, Pomonis JD. 2012. The monosodium iodoacetate model of osteoarthritis pain in the rat. Methods Mol Biol 851:239–248.
    • (2012) Methods Mol Biol , vol.851 , pp. 239-248
    • Marker, C.L.1    Pomonis, J.D.2
  • 119
    • 0021345553 scopus 로고
    • Dibenz[b,e]oxepinalkanoic acids as nonsteroidal anti-inflammatory agents. 4. Synthesis and evaluation of 4-(4,10-dihydro-10-oxothieno[3,2-c] [1]benzoxepin-8-yl)butanol and -butyric acid and related derivatives
    • Martin LL, Setescak LL, Spaulding TC, Helsley GC. 1984. Dibenz[b,e]oxepinalkanoic acids as nonsteroidal anti-inflammatory agents. 4. Synthesis and evaluation of 4-(4,10-dihydro-10-oxothieno[3,2-c] [1]benzoxepin-8-yl)butanol and -butyric acid and related derivatives. J Med Chem 27:372–376.
    • (1984) J Med Chem , vol.27 , pp. 372-376
    • Martin, L.L.1    Setescak, L.L.2    Spaulding, T.C.3    Helsley, G.C.4
  • 120
    • 0033027735 scopus 로고    scopus 로고
    • Spinal cannabinoids are antiallodynic in rats with persistent inflammation
    • Martin WJ, Loo CM, Basbaum AI. 1999a. Spinal cannabinoids are antiallodynic in rats with persistent inflammation. Pain 82:199–205.
    • (1999) Pain , vol.82 , pp. 199-205
    • Martin, W.J.1    Loo, C.M.2    Basbaum, A.I.3
  • 121
    • 0033586315 scopus 로고    scopus 로고
    • Anatomical basis for cannabinoid-induced antinociception as revealed by intracerebral microinjections
    • Martin WJ, Coffin PO, Attias E, Balinsky M, Tsou K, Walker JM. 1999b. Anatomical basis for cannabinoid-induced antinociception as revealed by intracerebral microinjections. Brain Res 822:237–242.
    • (1999) Brain Res , vol.822 , pp. 237-242
    • Martin, W.J.1    Coffin, P.O.2    Attias, E.3    Balinsky, M.4    Tsou, K.5    Walker, J.M.6
  • 122
  • 123
    • 84961213966 scopus 로고    scopus 로고
    • Early postoperative nociceptive threshold and production of brain-derived neurotrophic factor induced by plantar incision are not influenced with minocycline in a rat: role of spinal microglia
    • Masaki E, Mizuta K, Ohtani N, Kido K. 2016. Early postoperative nociceptive threshold and production of brain-derived neurotrophic factor induced by plantar incision are not influenced with minocycline in a rat: role of spinal microglia. Neurosignals 24:15–24.
    • (2016) Neurosignals , vol.24 , pp. 15-24
    • Masaki, E.1    Mizuta, K.2    Ohtani, N.3    Kido, K.4
  • 125
    • 34249017949 scopus 로고    scopus 로고
    • Ziconotide: a review of its pharmacology and use in the treatment of pain
    • McGivern JG. 2007. Ziconotide: a review of its pharmacology and use in the treatment of pain. Neuropsychiatr Dis Treat 3:69–85.
    • (2007) Neuropsychiatr Dis Treat , vol.3 , pp. 69-85
    • McGivern, J.G.1
  • 129
    • 84866175191 scopus 로고    scopus 로고
    • Drosophila as a tool for studying the conserved genetics of pain
    • Milinkeviciute G, Gentile C, Neely GG. 2012. Drosophila as a tool for studying the conserved genetics of pain. Clin Genet 82:359–366.
    • (2012) Clin Genet , vol.82 , pp. 359-366
    • Milinkeviciute, G.1    Gentile, C.2    Neely, G.G.3
  • 130
    • 0034882230 scopus 로고    scopus 로고
    • Strain and model differences in behavioral outcomes after spinal cord injury in rat
    • Mills CD, Hains BC, Johnson KM, Hulsebosch CE. 2001. Strain and model differences in behavioral outcomes after spinal cord injury in rat. J Neurotrauma 18:743–756.
    • (2001) J Neurotrauma , vol.18 , pp. 743-756
    • Mills, C.D.1    Hains, B.C.2    Johnson, K.M.3    Hulsebosch, C.E.4
  • 131
    • 62849090906 scopus 로고    scopus 로고
    • Animal models of pain: progress and challenges
    • Mogil JS. 2009. Animal models of pain: progress and challenges. Nat Rev Neurosci 10:283–294.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 283-294
    • Mogil, J.S.1
  • 132
    • 84872014582 scopus 로고    scopus 로고
    • Sex differences in pain and pain inhibition: multiple explanations of a controversial phenomenon
    • Mogil JS. 2012. Sex differences in pain and pain inhibition: multiple explanations of a controversial phenomenon. Nat Rev Neurosci 13:859–866.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 859-866
    • Mogil, J.S.1
  • 134
    • 0033993690 scopus 로고    scopus 로고
    • Sex differences in thermal nociception and morphine antinociception in rodents depend on genotype
    • Mogil JS, Chesler EJ, Wilson SG, Juraska JM, Sternberg WF. 2000. Sex differences in thermal nociception and morphine antinociception in rodents depend on genotype. Neurosci Biobehav Rev 24:375–389.
    • (2000) Neurosci Biobehav Rev , vol.24 , pp. 375-389
    • Mogil, J.S.1    Chesler, E.J.2    Wilson, S.G.3    Juraska, J.M.4    Sternberg, W.F.5
  • 135
    • 79551612533 scopus 로고    scopus 로고
    • The necessity of animal models in pain research
    • Mogil JS, Davis KD, Derbyshire SW. 2010. The necessity of animal models in pain research. Pain 151:12–17.
    • (2010) Pain , vol.151 , pp. 12-17
    • Mogil, J.S.1    Davis, K.D.2    Derbyshire, S.W.3
  • 139
    • 0023715818 scopus 로고
    • Methodological refinements to the mouse paw formalin test: an animal model of tonic pain
    • Murray CW, Porreca F, Cowan A. 1988. Methodological refinements to the mouse paw formalin test: an animal model of tonic pain. J Pharmacol Methods 20:175–186.
    • (1988) J Pharmacol Methods , vol.20 , pp. 175-186
    • Murray, C.W.1    Porreca, F.2    Cowan, A.3
  • 140
    • 0030631403 scopus 로고    scopus 로고
    • Collagen-induced arthritis, an animal model of autoimmunity
    • Myers LK, Rosloniec EF, Cremer MA, Kang AH. 1997. Collagen-induced arthritis, an animal model of autoimmunity. Life Sci 61:1861–1878.
    • (1997) Life Sci , vol.61 , pp. 1861-1878
    • Myers, L.K.1    Rosloniec, E.F.2    Cremer, M.A.3    Kang, A.H.4
  • 141
    • 0037316882 scopus 로고    scopus 로고
    • Congenital insensitivity to pain: an update
    • Nagasako EM, Oaklander AL, Dworkin RH. 2003. Congenital insensitivity to pain: an update. Pain 101:213–219.
    • (2003) Pain , vol.101 , pp. 213-219
    • Nagasako, E.M.1    Oaklander, A.L.2    Dworkin, R.H.3
  • 142
    • 2442503913 scopus 로고    scopus 로고
    • Modulation of morphine analgesia by site-specific N-methyl-D-aspartate receptor antagonists: dependence on sex, site of antagonism, morphine dose, and time
    • Nemmani KVS, Grisel JE, Stowe JR, Smith-Carliss R, Mogil JS. 2004. Modulation of morphine analgesia by site-specific N-methyl-D-aspartate receptor antagonists: dependence on sex, site of antagonism, morphine dose, and time. Pain 109:274–283.
    • (2004) Pain , vol.109 , pp. 274-283
    • Nemmani, K.V.S.1    Grisel, J.E.2    Stowe, J.R.3    Smith-Carliss, R.4    Mogil, J.S.5
  • 143
    • 0000725757 scopus 로고    scopus 로고
    • Models of visceral nociception
    • Ness TJ. 1999. Models of visceral nociception. ILAR J 40:119–128.
    • (1999) ILAR J , vol.40 , pp. 119-128
    • Ness, T.J.1
  • 144
    • 0023883691 scopus 로고
    • Colorectal distension as a noxious visceral stimulus: physiologic and pharmacologic characterization of pseudaffective reflexes in the rat
    • Ness TJ, Gebhart GF. 1988. Colorectal distension as a noxious visceral stimulus: physiologic and pharmacologic characterization of pseudaffective reflexes in the rat. Brain Res 450:153–169.
    • (1988) Brain Res , vol.450 , pp. 153-169
    • Ness, T.J.1    Gebhart, G.F.2
  • 146
    • 70349303776 scopus 로고    scopus 로고
    • Diabetic painful and insensate neuropathy: pathogenesis and potential treatments
    • Obrosova IG. 2009. Diabetic painful and insensate neuropathy: pathogenesis and potential treatments. Neurotherapeutics 6:638–647.
    • (2009) Neurotherapeutics , vol.6 , pp. 638-647
    • Obrosova, I.G.1
  • 147
    • 42449107733 scopus 로고    scopus 로고
    • Genetic mutations that prevent pain: implications for future pain medication
    • Oertel B, Lötsch J. 2008. Genetic mutations that prevent pain: implications for future pain medication. Pharmacogenomics 9:179–194.
    • (2008) Pharmacogenomics , vol.9 , pp. 179-194
    • Oertel, B.1    Lötsch, J.2
  • 148
    • 45849112147 scopus 로고    scopus 로고
    • Fatty acid amide hydrolase inhibition enhances the antiallodynic actions of endocannabinoids in a model of acute pain adapted for the mouse
    • Palmer JA, Higuera ES, Chang L, Chaplan SR. 2008. Fatty acid amide hydrolase inhibition enhances the antiallodynic actions of endocannabinoids in a model of acute pain adapted for the mouse. Neuroscience 154:1554–1561.
    • (2008) Neuroscience , vol.154 , pp. 1554-1561
    • Palmer, J.A.1    Higuera, E.S.2    Chang, L.3    Chaplan, S.R.4
  • 149
    • 33646142292 scopus 로고    scopus 로고
    • The endocannabinoid 2-AG protects the blood–brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines
    • Panikashvili D, Shein NA, Mechoulam R, Trembovler V, Kohen R, Alexandrovich A, Shohami E. 2006. The endocannabinoid 2-AG protects the blood–brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. Neurobiol Dis 22:257–264.
    • (2006) Neurobiol Dis , vol.22 , pp. 257-264
    • Panikashvili, D.1    Shein, N.A.2    Mechoulam, R.3    Trembovler, V.4    Kohen, R.5    Alexandrovich, A.6    Shohami, E.7
  • 150
    • 80053099026 scopus 로고    scopus 로고
    • Rodent empathy and affective neuroscience
    • Panksepp JB, Lahvis GP. 2011. Rodent empathy and affective neuroscience. Neurosci Biobehav Rev 35:1864–1875.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1864-1875
    • Panksepp, J.B.1    Lahvis, G.P.2
  • 152
    • 84901419087 scopus 로고    scopus 로고
    • Improving the translation of analgesic drugs to the clinic: animal models of neuropathic pain
    • Percie du Sert N, Rice ASC. 2014. Improving the translation of analgesic drugs to the clinic: animal models of neuropathic pain. Br J Pharmacol 171:2951–2963.
    • (2014) Br J Pharmacol , vol.171 , pp. 2951-2963
    • Percie du Sert, N.1    Rice, A.S.C.2
  • 154
    • 79958754583 scopus 로고    scopus 로고
    • Analysis of hyperalgesia time courses in humans after painful electrical high-frequency stimulation identifies a possible transition from early to late LTP-like pain plasticity
    • Pfau DB, Klein T, Putzer D, Pogatzki-Zahn EM, Treede R-D, Magerl W. 2011. Analysis of hyperalgesia time courses in humans after painful electrical high-frequency stimulation identifies a possible transition from early to late LTP-like pain plasticity. Pain 152:1532–1539.
    • (2011) Pain , vol.152 , pp. 1532-1539
    • Pfau, D.B.1    Klein, T.2    Putzer, D.3    Pogatzki-Zahn, E.M.4    Treede, R.-D.5    Magerl, W.6
  • 155
    • 81355147127 scopus 로고    scopus 로고
    • Central pain mechanisms in chronic pain states—maybe it is all in their head
    • Phillips K, Clauw DJ. 2011. Central pain mechanisms in chronic pain states—maybe it is all in their head. Best Pract Res Clin Rheumatol 25:141–154.
    • (2011) Best Pract Res Clin Rheumatol , vol.25 , pp. 141-154
    • Phillips, K.1    Clauw, D.J.2
  • 156
    • 0035926029 scopus 로고    scopus 로고
    • [Impact of age on pain perception and analgesic pharmacology]
    • Pickering G, Jourdan D, Eschalier A, Dubray C. 2001. [Impact of age on pain perception and analgesic pharmacology]. Presse Méd 30:754–758.
    • (2001) Presse Méd , vol.30 , pp. 754-758
    • Pickering, G.1    Jourdan, D.2    Eschalier, A.3    Dubray, C.4
  • 157
    • 33847148953 scopus 로고    scopus 로고
    • Blocking sodium channels to treat neuropathic pain
    • Priest BT, Kaczorowski GJ. 2007. Blocking sodium channels to treat neuropathic pain. Expert Opin Ther Targets 11:291–306.
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 291-306
    • Priest, B.T.1    Kaczorowski, G.J.2
  • 158
    • 0025946791 scopus 로고
    • Congenital insensitivity to pain
    • Protheroe SM. 1991. Congenital insensitivity to pain. J R Soc Med 84:558–559.
    • (1991) J R Soc Med , vol.84 , pp. 558-559
    • Protheroe, S.M.1
  • 159
    • 84960959252 scopus 로고
    • A method for measurement of analgesic activity on inflamed tissue
    • Randall LO, Selitto JJ. 1957. A method for measurement of analgesic activity on inflamed tissue. Arch Int Pharmacodyn Ther 111:409–419.
    • (1957) Arch Int Pharmacodyn Ther , vol.111 , pp. 409-419
    • Randall, L.O.1    Selitto, J.J.2
  • 160
    • 70449633251 scopus 로고    scopus 로고
    • Critical role of nociceptor plasticity in chronic pain
    • Reichling DB, Levine JD. 2009. Critical role of nociceptor plasticity in chronic pain. Trends Neurosci 32:611–618.
    • (2009) Trends Neurosci , vol.32 , pp. 611-618
    • Reichling, D.B.1    Levine, J.D.2
  • 161
    • 84971275478 scopus 로고    scopus 로고
    • A comparative behavioural study of mechanical hypersensitivity in two pain models in rats and humans
    • Reitz M-C, Hrncic D, Treede R-D, Caspani O. 2016. A comparative behavioural study of mechanical hypersensitivity in two pain models in rats and humans. Pain 157:1248–1258.
    • (2016) Pain , vol.157 , pp. 1248-1258
    • Reitz, M.-C.1    Hrncic, D.2    Treede, R.-D.3    Caspani, O.4
  • 162
    • 84921027022 scopus 로고    scopus 로고
    • The power of automated behavioural homecage technologies in characterizing disease progression in laboratory mice: a review
    • Richardson CA. 2015. The power of automated behavioural homecage technologies in characterizing disease progression in laboratory mice: a review. Appl Anim Behav Sci 163:19–27.
    • (2015) Appl Anim Behav Sci , vol.163 , pp. 19-27
    • Richardson, C.A.1
  • 164
    • 84882574568 scopus 로고    scopus 로고
    • Pain, motor, and gait assessment of murine osteoarthritis in a cruciate ligament transection model
    • Ruan MZC, Patel RM, Dawson BC, Jiang M-M, Lee BHL. 2013. Pain, motor, and gait assessment of murine osteoarthritis in a cruciate ligament transection model. Osteoarthritis Cartilage 21:1355–1364.
    • (2013) Osteoarthritis Cartilage , vol.21 , pp. 1355-1364
    • Ruan, M.Z.C.1    Patel, R.M.2    Dawson, B.C.3    Jiang, M.-M.4    Lee, B.H.L.5
  • 165
    • 0036844605 scopus 로고    scopus 로고
    • Epidemiology and impact on quality of life of postherpetic neuralgia and painful diabetic neuropathy
    • Schmader KE. 2002. Epidemiology and impact on quality of life of postherpetic neuralgia and painful diabetic neuropathy. Clin J Pain 18:350–354.
    • (2002) Clin J Pain , vol.18 , pp. 350-354
    • Schmader, K.E.1
  • 167
    • 0037144134 scopus 로고    scopus 로고
    • Actions of intrathecal omega-conotoxins CVID, GVIA, MVIIA, and morphine in acute and neuropathic pain in the rat
    • Scott DA, Wright CE, Angus JA. 2002. Actions of intrathecal omega-conotoxins CVID, GVIA, MVIIA, and morphine in acute and neuropathic pain in the rat. Eur J Pharmacol 451:279–286.
    • (2002) Eur J Pharmacol , vol.451 , pp. 279-286
    • Scott, D.A.1    Wright, C.E.2    Angus, J.A.3
  • 168
    • 0025167399 scopus 로고
    • A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury
    • Seltzer Z, Dubner R, Shir Y. 1990. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 43:205–218.
    • (1990) Pain , vol.43 , pp. 205-218
    • Seltzer, Z.1    Dubner, R.2    Shir, Y.3
  • 169
    • 0035252324 scopus 로고    scopus 로고
    • Correlation of intact sensibility and neuropathic pain-related behaviors in eight inbred and outbred rat strains and selection lines
    • Shir Y, Zeltser R, Vatine J-J, Carmi G, Belfer I, Zangen A, Overstreet D, Raber P, Seltzer Z. 2001. Correlation of intact sensibility and neuropathic pain-related behaviors in eight inbred and outbred rat strains and selection lines. Pain 90:75–82.
    • (2001) Pain , vol.90 , pp. 75-82
    • Shir, Y.1    Zeltser, R.2    Vatine, J.-J.3    Carmi, G.4    Belfer, I.5    Zangen, A.6    Overstreet, D.7    Raber, P.8    Seltzer, Z.9
  • 170
    • 0032454062 scopus 로고    scopus 로고
    • Blockade of N- and P/Q-type calcium channels reduces the secondary heat hyperalgesia induced by acute inflammation
    • Sluka KA. 1998. Blockade of N- and P/Q-type calcium channels reduces the secondary heat hyperalgesia induced by acute inflammation. J Pharmacol Exp Ther 287:232–237.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 232-237
    • Sluka, K.A.1
  • 171
    • 0036217174 scopus 로고    scopus 로고
    • The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slices
    • Smith MT, Cabot PJ, Ross FB, Robertson AD, Lewis RJ. 2002. The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slices. Pain 96:119–127.
    • (2002) Pain , vol.96 , pp. 119-127
    • Smith, M.T.1    Cabot, P.J.2    Ross, F.B.3    Robertson, A.D.4    Lewis, R.J.5
  • 175
    • 79960026104 scopus 로고    scopus 로고
    • Evaluation of leukemia inhibitory factor (LIF) in a rat model of postoperative pain
    • Spofford CM, Mohan S, Kang S, Jang JH, Brennan TJ. 2011. Evaluation of leukemia inhibitory factor (LIF) in a rat model of postoperative pain. J Pain 12:819–832.
    • (2011) J Pain , vol.12 , pp. 819-832
    • Spofford, C.M.1    Mohan, S.2    Kang, S.3    Jang, J.H.4    Brennan, T.J.5
  • 176
    • 0024153212 scopus 로고
    • Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: alterations in behavior and nociceptive thresholds
    • Stein C, Millan MJ, Herz A. 1988. Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: alterations in behavior and nociceptive thresholds. Pharmacol Biochem Behav 31:445–451.
    • (1988) Pharmacol Biochem Behav , vol.31 , pp. 445-451
    • Stein, C.1    Millan, M.J.2    Herz, A.3
  • 178
    • 0027933755 scopus 로고
    • Conditioned place preference paradigm: a novel approach for analgesic drug assessment against chronic pain
    • Sufka KJ. 1994. Conditioned place preference paradigm: a novel approach for analgesic drug assessment against chronic pain. Pain 58:355–366.
    • (1994) Pain , vol.58 , pp. 355-366
    • Sufka, K.J.1
  • 179
    • 84955328130 scopus 로고    scopus 로고
    • Roles of proton-sensing receptors in the transition from acute to chronic pain
    • Sun WH, Chen CC. 2016. Roles of proton-sensing receptors in the transition from acute to chronic pain. J Dent Res 95:135–142.
    • (2016) J Dent Res , vol.95 , pp. 135-142
    • Sun, W.H.1    Chen, C.C.2
  • 180
    • 0034194051 scopus 로고    scopus 로고
    • Allodynia and hyperalgesia induced by herpes simplex virus type-1 infection in mice
    • Takasaki I, Andoh T, Shiraki K, Kuraishi Y. 2000. Allodynia and hyperalgesia induced by herpes simplex virus type-1 infection in mice. Pain 86:95–101.
    • (2000) Pain , vol.86 , pp. 95-101
    • Takasaki, I.1    Andoh, T.2    Shiraki, K.3    Kuraishi, Y.4
  • 181
    • 84859639690 scopus 로고    scopus 로고
    • Reproducibility of electronic von Frey and von Frey monofilaments testing
    • Tena B, Escobar B, Arguis MJ, Cantero C, Rios J, Gomar C. 2012. Reproducibility of electronic von Frey and von Frey monofilaments testing. Clin J Pain 28:318–323.
    • (2012) Clin J Pain , vol.28 , pp. 318-323
    • Tena, B.1    Escobar, B.2    Arguis, M.J.3    Cantero, C.4    Rios, J.5    Gomar, C.6
  • 185
    • 33645987927 scopus 로고    scopus 로고
    • The epidemiology of chronic pain of predominantly neuropathic origin. Results from a general population survey
    • Torrance N, Smith BH, Bennett MI, Lee AJ. 2006. The epidemiology of chronic pain of predominantly neuropathic origin. Results from a general population survey. J Pain 7:281–289.
    • (2006) J Pain , vol.7 , pp. 281-289
    • Torrance, N.1    Smith, B.H.2    Bennett, M.I.3    Lee, A.J.4
  • 186
    • 84861528073 scopus 로고    scopus 로고
    • P2X4 purinoceptor signaling in chronic pain
    • Trang T, Salter MW. 2012. P2X4 purinoceptor signaling in chronic pain. Purinergic Signal 8:621–628.
    • (2012) Purinergic Signal , vol.8 , pp. 621-628
    • Trang, T.1    Salter, M.W.2
  • 188
    • 35348893714 scopus 로고    scopus 로고
    • Mental disorders in chronic pain patients
    • Twillman RK. 2007. Mental disorders in chronic pain patients. J Pain Palliat Care Pharmacother 21:13–19.
    • (2007) J Pain Palliat Care Pharmacother , vol.21 , pp. 13-19
    • Twillman, R.K.1
  • 189
    • 27644515075 scopus 로고    scopus 로고
    • A behavioral model of neuropathic pain induced by ligation of the common peroneal nerve in mice
    • Vadakkan KI, Jia YH, Zhuo M. 2005. A behavioral model of neuropathic pain induced by ligation of the common peroneal nerve in mice. J Pain 6:747–756.
    • (2005) J Pain , vol.6 , pp. 747-756
    • Vadakkan, K.I.1    Jia, Y.H.2    Zhuo, M.3
  • 190
    • 0028342682 scopus 로고
    • Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatment
    • van den Berg WB, Joosten LA, Helsen M, van de Loo FA. 1994. Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatment. Clin Exp Immunol 9:237–243.
    • (1994) Clin Exp Immunol , vol.9 , pp. 237-243
    • van den Berg, W.B.1    Joosten, L.A.2    Helsen, M.3    van de Loo, F.A.4
  • 192
    • 84857287844 scopus 로고    scopus 로고
    • Deconstructing the neuropathic pain phenotype to reveal neural mechanisms
    • von Hehn CA, Baron R, Woolf CJ. 2012. Deconstructing the neuropathic pain phenotype to reveal neural mechanisms. Neuron 73:638–652.
    • (2012) Neuron , vol.73 , pp. 638-652
    • von Hehn, C.A.1    Baron, R.2    Woolf, C.J.3
  • 194
    • 33645794750 scopus 로고    scopus 로고
    • Intrathecal ziconotide in the treatment of chronic nonmalignant pain: a randomized, double-blind, placebo-controlled clinical trial
    • Wallace MS, Charapata SG, Fisher R, Byas-Smith M, Staats PS, Mayo M, McGuire D, Ellis D, The Ziconotide Nonmalignant Pain Study 96–002 Group. 2006. Intrathecal ziconotide in the treatment of chronic nonmalignant pain: a randomized, double-blind, placebo-controlled clinical trial. Neuromodulation 9:75–86.
    • (2006) Neuromodulation , vol.9 , pp. 75-86
    • Wallace, M.S.1    Charapata, S.G.2    Fisher, R.3    Byas-Smith, M.4    Staats, P.S.5    Mayo, M.6    McGuire, D.7    Ellis, D.8
  • 196
    • 0142043867 scopus 로고    scopus 로고
    • Animal and cellular models of chronic pain
    • Wang LX, Wang ZJ. 2003. Animal and cellular models of chronic pain. Adv Drug Deliv Rev 55:949–965.
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 949-965
    • Wang, L.X.1    Wang, Z.J.2
  • 198
    • 0024799201 scopus 로고
    • The mec-3 gene of Caenorhabditis elegans requires its own product for maintained expression and is expressed in three neuronal cell types
    • Way JC, Chalfie M. 1989. The mec-3 gene of Caenorhabditis elegans requires its own product for maintained expression and is expressed in three neuronal cell types. Genes Dev 3:1823–1833.
    • (1989) Genes Dev , vol.3 , pp. 1823-1833
    • Way, J.C.1    Chalfie, M.2
  • 200
    • 28244465212 scopus 로고    scopus 로고
    • Sex differences in pain perception
    • Wiesenfeld-Hallin Z. 2005. Sex differences in pain perception. Gend Med 2:137–145.
    • (2005) Gend Med , vol.2 , pp. 137-145
    • Wiesenfeld-Hallin, Z.1
  • 204
    • 0026644298 scopus 로고
    • Antitumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
    • Williams RO, Feldmann M, Maini RN. 1992. Antitumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci U S A 89:9784–9788.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 9784-9788
    • Williams, R.O.1    Feldmann, M.2    Maini, R.N.3
  • 205
    • 0021014399 scopus 로고
    • Evidence for a central component of postinjury pain hypersensitivity
    • Woolf CJ. 1983. Evidence for a central component of postinjury pain hypersensitivity. Nature 306:686–688.
    • (1983) Nature , vol.306 , pp. 686-688
    • Woolf, C.J.1
  • 206
    • 79951579664 scopus 로고    scopus 로고
    • Central sensitization: implications for the diagnosis and treatment of pain
    • Woolf CJ. 2011. Central sensitization: implications for the diagnosis and treatment of pain. Pain 152:S2–S15.
    • (2011) Pain , vol.152 , pp. S2-S15
    • Woolf, C.J.1
  • 207
    • 0034625770 scopus 로고    scopus 로고
    • Neuronal plasticity: increasing the gain in pain
    • Woolf CJ, Salter MW. 2000. Neuronal plasticity: increasing the gain in pain. Science 288:1765.
    • (2000) Science , vol.288 , pp. 1765
    • Woolf, C.J.1    Salter, M.W.2
  • 208
    • 0000811019 scopus 로고
    • The evaluation of the analgesic action of pethidine hydrochloride (demerol)
    • Woolfe G, Macdonald AD. 1944. The evaluation of the analgesic action of pethidine hydrochloride (demerol). J Pharmacol Exp Ther 80:300–307.
    • (1944) J Pharmacol Exp Ther , vol.80 , pp. 300-307
    • Woolfe, G.1    Macdonald, A.D.2
  • 209
    • 84906690352 scopus 로고    scopus 로고
    • Emotional consequences of neuropathic pain: insight from preclinical studies
    • Yalcin I, Barthas F, Barrot M. 2014. Emotional consequences of neuropathic pain: insight from preclinical studies. Neurosci Biobehav Rev 47:154–164.
    • (2014) Neurosci Biobehav Rev , vol.47 , pp. 154-164
    • Yalcin, I.1    Barthas, F.2    Barrot, M.3
  • 210
    • 0032103141 scopus 로고    scopus 로고
    • Differential effects of intrathecally administered N- and P-type voltage-sensitive calcium channel blockers upon two models of experimental mononeuropathy in the rat
    • Yamamoto T, Sakashita Y. 1998. Differential effects of intrathecally administered N- and P-type voltage-sensitive calcium channel blockers upon two models of experimental mononeuropathy in the rat. Brain Res 794:329–332.
    • (1998) Brain Res , vol.794 , pp. 329-332
    • Yamamoto, T.1    Sakashita, Y.2
  • 211
    • 85017493479 scopus 로고    scopus 로고
    • SDF1-CXCR4 signaling contributes to the transition from acute to chronic pain state
    • [E-pub ahead of print]
    • Yang F, Sun W, Luo W-J, Yang Y, Yang F, Wang X-L, Chen J. 2016. SDF1-CXCR4 signaling contributes to the transition from acute to chronic pain state. Mol Neurobiol [E-pub ahead of print].
    • (2016) Mol Neurobiol
    • Yang, F.1    Sun, W.2    Luo, W.-J.3    Yang, Y.4    Yang, F.5    Wang, X.-L.6    Chen, J.7
  • 212
    • 67349189415 scopus 로고    scopus 로고
    • Intracisternal administration of COX inhibitors attenuates mechanical allodynia following compression of the trigeminal ganglion in rats
    • Yang GY, Lee MK, Bae YC, Ahn DK. 2009. Intracisternal administration of COX inhibitors attenuates mechanical allodynia following compression of the trigeminal ganglion in rats. Prog Neuropsychopharmacol Biol Psychiatry 33:589–595.
    • (2009) Prog Neuropsychopharmacol Biol Psychiatry , vol.33 , pp. 589-595
    • Yang, G.Y.1    Lee, M.K.2    Bae, Y.C.3    Ahn, D.K.4
  • 213
    • 84859851531 scopus 로고    scopus 로고
    • The effects of age on pain sensitivity: preclinical studies
    • Yezierski RP. 2012. The effects of age on pain sensitivity: preclinical studies. Pain Med 13:S27–S36.
    • (2012) Pain Med , vol.13 , pp. S27-S36
    • Yezierski, R.P.1
  • 214
    • 0028558684 scopus 로고
    • Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain
    • Yoon C, Young Wook Y, Heung Sik N, Sun Ho K, Jin Mo C. 1994. Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain. Pain 59:369–376.
    • (1994) Pain , vol.59 , pp. 369-376
    • Yoon, C.1    Young Wook, Y.2    Heung Sik, N.3    Sun Ho, K.4    Jin Mo, C.5
  • 215
    • 37149032448 scopus 로고    scopus 로고
    • Transition from acute to chronic pain and disability: a model including cognitive, affective, and trauma factors
    • Young Casey C, Greenberg MA, Nicassio PM, Harpin RE, Hubbard D. 2008. Transition from acute to chronic pain and disability: a model including cognitive, affective, and trauma factors. Pain 134:69–79.
    • (2008) Pain , vol.134 , pp. 69-79
    • Young Casey, C.1    Greenberg, M.A.2    Nicassio, P.M.3    Harpin, R.E.4    Hubbard, D.5
  • 216
    • 84925848044 scopus 로고    scopus 로고
    • Can modulating inflammatory response be a good strategy to treat neuropathic pain?
    • Zhang J, Echeverry S, Lim TKY, Lee SH, Shi XQ, Huang H. 2015. Can modulating inflammatory response be a good strategy to treat neuropathic pain? Curr Pharm Des 21:831–839.
    • (2015) Curr Pharm Des , vol.21 , pp. 831-839
    • Zhang, J.1    Echeverry, S.2    Lim, T.K.Y.3    Lee, S.H.4    Shi, X.Q.5    Huang, H.6
  • 217
    • 77957898181 scopus 로고    scopus 로고
    • Animal models of inflammatory pain
    • In, Ma C, Zhang J-M, editors., New York, Humana Press, p
    • Zhang R-X, Ren K. 2011. Animal models of inflammatory pain. In: Ma C, Zhang J-M, editors. Animal models of pain. New York: Humana Press. p 23–40.
    • (2011) Animal models of pain , pp. 23-40
    • Zhang, R.-X.1    Ren, K.2
  • 218
    • 0034812709 scopus 로고    scopus 로고
    • Murine interstrain polymorphisms alter gene targeting frequencies at the mu opioid receptor locus in embryonic stem cells
    • Zhou L, Rowley DL, Mi Q-S, Sefcovic N, Matthes HWD, Kieffer BL, Donovan DM. 2014. Murine interstrain polymorphisms alter gene targeting frequencies at the mu opioid receptor locus in embryonic stem cells. Mamm Genome 12:772–778.
    • (2014) Mamm Genome , vol.12 , pp. 772-778
    • Zhou, L.1    Rowley, D.L.2    Mi, Q.-S.3    Sefcovic, N.4    Matthes, H.W.D.5    Kieffer, B.L.6    Donovan, D.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.