The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines

Neurobiology of Disease

Volumn 22, Issue 2, 2006, Pages 257-264

  Panikashvili, David ^a   Shein, Na'ama A ^a   Mechoulam, Raphael ^a   Trembovler, Victoria ^a   Kohen, Ron ^a   Alexandrovich, Alexander ^a   Shohami, Esther ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

BBB integrity; Cytokines; Endocannabinoids; Inflammation; Neuroprotection; Reactive oxygen species; Traumatic brain injury

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ANTIOXIDANT; CYTOKINE; ENDOCANNABINOID; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; DRUG EFFECT; HEAD INJURY; MOUSE; NEUROPROTECTION; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTIOXIDANTS; ARACHIDONIC ACIDS; BLOOD-BRAIN BARRIER; CYTOKINES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENCEPHALITIS; GENE EXPRESSION REGULATION; GLYCERIDES; HEAD INJURIES, CLOSED; INTERLEUKIN-1; INTERLEUKIN-6; MALE; MICE; NEUROPROTECTIVE AGENTS; REACTION TIME; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33646142292     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.11.004     Document Type: Article

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