A robust automated system elucidates mouse home cage behavioral structure

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 52, 2008, Pages 20575-20582

  Goulding, Evan H ^a   Schenk, A Katrin ^a   Juneja, Punita ^a   MacKay, Adrienne W ^a   Wade, Jennifer M ^a   Tecott, Laurence H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Circadian; Ingestion; Obesity; Phenotyping

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL HOUSING; ARTICLE; BEHAVIOR CHANGE; CIRCADIAN RHYTHM; CONTROLLED STUDY; ENERGY BALANCE; GENE MUTATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BEHAVIOR, ANIMAL; ENERGY METABOLISM; FEMALE; MALE; MICE; MICE, OBESE;

MAMMALIA; MUS;

EID: 58549100058     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0809053106     Document Type: Article

References (55)

1. de Visser L, van den Bos R, Kuurman WW, Kas MJ, Spruijt BM (2006) Novel approach to the behavioural characterization of inbred mice: Automated home cage observations. Genes Brain Behav 5:458-466.
2. Tecott LH, Nestler EJ (2004) Neurobehavioral assessment in the information age. Nat Neurosci 7:462-466.
3. McFarland DJ (1977) Decision making in animals. Nature 269:15-21.
4. Oatley K (1970) Brain mechanisms and motivation. Nature 225:797-801.
5. Prescott TJ, Redgrave P, Gurney K (1999) Layered control architectures in robots and vertebrates. Adaptive Behav 7:99-127.
6. Casadesus G, Shukitt-Hale B, Joseph JA (2001) Automated measurement of age-related changes in the locomotor response to environmental novelty and home-cage activity. Mechan Age Develop 122:1887-1897.
7. Gannon KS, Smith JC, Henderson R, Hendrick P (1992) A system for studying the microstructure of ingestive behavior in mice. Physiol Behav 51:515-521.
8. Chen SA, et al. (2006) Unlimited access to heroin self-administration: Independent motivational markers of opiate dependence. Neuropsychopharmacol 31:2692-2707.
9. Millecamps M, et al. (2005) Circadian pattern ofspontaneousbehavior in monarthritic rats: A novel global approach to evaluation of chronic pain and treatment effectiveness. Arthritis Rheumatism 52:3470-3478.
10. Steele AD, Jackson WS, King OD, Lindquist S (2007) The power of automated highresolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases. Proc Natl Acad Sci USA 104:1983-1988.
11. Tamborini P, Sigg H, Zbinden G (1989) Quantitative analysis of rat activity in the home cage by infrared monitoring. Application to the acute toxicity testing of acetanilide and phenylmercuric acetate. Arch Toxicol 63:85-96.
12. Tang X, Sanford LD (2005) Home cage activity and activity-based measures of anxiety in 129P3/J, 129X1/SvJ and C57BL/6J mice. Physiol Behav 84:105-115.
13. Zorrilla EP, et al. (2005) Measuring meals: Structure of prandial food and water intake of rats. Am J Physiol 288:R1450-R1467.
14. Bonasera SJ, Schenk AK, Luxenberg EJ, Tecott LH (2008) A novel method for automatic quantification of psychostimulant-evoked route-tracing stereotypy: Application to Mus musculus. Psychopharmacol 196:591-602.
15. Brunner D, Nestler E, Leahy E (2002) In need of high-throughput behavioral systems. Drug Discovery Today 7:S107-S112.
16. Donohue KD, Medonza DC, Crane ER, O'Hara BF (2008) Assessment of a non-invasive high-throughput classifier for behaviours associated with sleep and wake in mice. Biomed Engineering Online 7:14.
17. Galsworthy MJ, et al. (2005) A comparison of wild-caught wood mice and bank voles in the Intellicage: Assessing exploration, daily activity patterns and place learning paradigms. Behav Brain Res 157:211-217.
18. Kas MJH, Malsen AD, Olivier B, Spruijt BM, van Ree JM (2008) Differential genetic regulation of motor activity and anxiety-related behaviors in mice using an automated home cage task. Behav Neurosci 122:769-776.
19. Risbrough VB, et al. (2006) Differential contributions of dopamine D-1, D-2, and D-3 receptors to MDMA-induced effects on locomotor behavior patterns in mice. Neuropsychopharmacol 31:2349-2358.
20. Herbers JM (1981) Time resources and laziness in animals. Oecologia 49:252-262.
21. Pyke GH (1979) The economics of territory size and time budget in the Golden-Winged Sunbird. Am Nat 114:131-145.
22. Halle S Stenseth NC eds (2000) Activity Patterns in Small Mammals: An Ecological Approach (Springer, Berlin).
23. Burt WH (1943) Territoriality and home range concepts as applied to mammals. J Mamalogy 24:346-352.
24. Gray SJ, et al. (1998) Microhabitat and spatial dispersion of the grassland mouse (Mus spretus Lataste). J Zool 246:299-308.
25. Samuel MD, Pierce DJ, Garton EO (1985) Identifying areas of concentrated use within the home range. J Animal Ecol 54:711-719.
26. Adams L, Davis SD (1967) The internal anatomy of home range. J Mamal 48:529-536.
27. Lima SL, Dill LM (1990) Behavioral decisions made under the risk of predation - A review and prospectus. Can J Zool 68:619-640.
28. Berdoy M (1993) Defining bouts of behavior: A three-process model. Animal Behav 46:387-396.
29. Machlis L (1977) Analysis of the temporal patterning of pecking in chicks. Behaviour 63:1-70.
30. Morgan CA, Emmans GC, Tolkamp BJ, Kyriazakis I (2000) Analysis of the feeding behavior of pigs using different models. Physiol Behav 68:395-403.
31. Tolkamp BJ, Kyriazakis II (1999) To split behaviour into bouts, log-transform the intervals. Anim Behav 57:807-817.
32. Langton SD, Collett D, Sibly RM (1995) Splitting behavior into bouts; A maximum likelihood approach. Behavior 132:781-799.
33. Friedman JM, Halaas JL (1998) Leptin and the regulation of body weight in mammals. Nature 395:763-770.
34. Wade JM, et al. (2008) Synergistic impairment of glucose homeostasis in ob/ob mice lacking functional serotonin 2C receptors. Endocrinology 149:955-961.
35. Nonogaki K, Abdallah L, Goulding EH, Bonasera SJ, Tecott LH (2003) Hyperactivity and reduced energy cost of physical activity in serotonin 5-HT2C receptor mutant mice. Diabetes 52:315-320.
36. 2C receptor gene. Nat Med 4:1152-1156.
37. Davison M (2004) Interresponse times and the structure of choice. Behaval Processes 66:173-187.
38. Levine JA (2007) Nonexercise activitythermogenesis- liberating the life-force. J Intern Med 262:273-287.
39. de Vries MW ed (1992) The Experience of Psychopathology: Investigating Mental Disorders in Their Natural Settings (Cambridge Univ Press, Cambridge, UK).
40. Aschoff J (1966) Circadian activity pattern with two peaks. Ecol 47:657-662.
41. Azen R, Budescu DV (2003) The dominance analysis approach for comparing predictors in multiple regression. Psychol Methods 8:129-148.
42. Drai D, Golani I (2001) SEE: A tool for the visualization and analysis of rodent exploratory behavior. Neurosci Biobehav R 25:409-426.
43. Kramer DL, McLaughlin RL (2001) The behavioral ecology of intermittent locomotion. Am Zool 41:137-153.
44. Antin J, Gibbs J, Holt J, Young RC, Smith GP (1975) Cholecystokinin elicits the complete behavioral sequence of satiety in rats. J Comp Physiol Psychol 89:784-790.
45. Ishii Y, Blundell JE, Halford JC, Rodgers RJ (2003) Effects of systematic variation in presatiation and fasting on the behavioural satiety sequence in male rats. Physiol Behav 79:227-238.
46. Collier G, Hirsch E, Hamlin PH (1972) The ecological determinants of reinforcement in the rat. Physiol Behav 9:705-716.
47. Johnson KG, Cabanac M (1982) Homeostatic competition in rats fed at varying distances from a thermoneutral refuge. Physiol Behav 29:715-720.
48. O'Reardon JP, et al. (2006) A randomized, placebo-controlled trial of sertraline in the treatment of night eating syndrome. Am J Psychiatry 163:893-898.
49. Deroche-Gamonet V, Belin D, Piazza PV (2004) Evidence for addiction-like behavior in the rat. Science 305:1014-1017.
50. Gonzalez MC, Hidalgo CA, Barabasi AL (2008) Understanding individual human mobility patterns. Nature 453:779-782.
51. Haynes SN, Yoshioka DT (2007) Clinical assessment applications of ambulatory biosensors. Psychol Assessment 19:44-57.
52. Hurling R, et al. (2007) Using internet and mobile phone technology to deliver an automated physical activity program: Randomized controlled trial. J Med Internet Res 9:25.
53. Laube P, Dennis T, Forer P, Walker M (2007) Movement beyond the snapshot - Dynamic analysis of geospatial lifelines. Comput Environ Urban Syst 31:481-501.
54. Mayes E, Duncan P (1986) Temporal patterns of feeding behavior in free-ranging horses. Behav 96:105-129.
55. Troendle JF (1995) A stepwise resampling method of multiple hypothesis-testing. J Am Stat Assoc 90:370-378.