Inter-strain differences of serotonergic inhibitory pain control in inbred mice

Molecular Pain

Volumn 6, Issue , 2010, Pages

  Wijnvoord, Nina ^a   Albuquerque, Boris ^a   Häussler, Annett ^a   Myrczek, Thekla ^a   Popp, Laura ^a   Tegeder, Irmgard ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FENCLONINE; SEROTONIN; FORMALDEHYDE; PROTEIN C FOS;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CHRONIC INFLAMMATION; CHRONIC PAIN; CONTROLLED STUDY; DORSAL RHIZOTOMY; GENETIC DIFFERENCE; HYPERALGESIA; HYPERSENSITIVITY REACTION; INBRED STRAIN; MALE; MOUSE; NERVE INJURY; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PAIN ASSESSMENT; PAIN THRESHOLD; PRIORITY JOURNAL; SEROTONIN BRAIN LEVEL; SEROTONINERGIC NERVE CELL; SEROTONINERGIC SYSTEM; SIGNAL TRANSDUCTION; SPINAL CORD DORSAL HORN; SPINAL CORD HEMISECTION; STRAIN DIFFERENCE; UPREGULATION; ANIMAL; BIOSYNTHESIS; CHRONIC DISEASE; DISEASE MODEL; INFLAMMATION; INJURY; MESENCEPHALON; METABOLISM; MOUSE STRAIN; NEURALGIA; NOCICEPTIVE RECEPTOR; PAIN; PATHOLOGY; POSTERIOR HORN CELL; SCIATIC NERVE; SPECIES DIFFERENCE; SPINAL GANGLION;

ANIMALS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; FORMALDEHYDE; GANGLIA, SPINAL; HYPERALGESIA; INFLAMMATION; MALE; MESENCEPHALON; MICE; MICE, INBRED STRAINS; NEURALGIA; NOCICEPTORS; PAIN; POSTERIOR HORN CELLS; PROTO-ONCOGENE PROTEINS C-FOS; SCIATIC NERVE; SEROTONIN; SPECIES SPECIFICITY; UP-REGULATION;

EID: 77958115292     PISSN: 17448069     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-8069-6-70     Document Type: Article

References (48)

1. Knabl J, Witschi R, Hosl K, Reinold H, Zeilhofer UB, Ahmadi S, Brockhaus J, Sergejeva M, Hess A, Brune K, Fritschy JM, Rudolph U, Mohler H, Zeilhofer HU. Reversal of pathological pain through specific spinal GABAA receptor subtypes. Nature 2008, 451(7176):330-4. 10.1038/nature06493, 18202657.
2. Ahmadi S, Lippross S, Neuhuber WL, Zeilhofer HU. PGE(2) selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons. Nat Neurosci 2002, 5(1):34-40. 10.1038/nn778, 11740501.
3. Scholz J, Broom DC, Youn DH, Mills CD, Kohno T, Suter MR, Moore KA, Decosterd I, Coggeshall RE, Woolf CJ. Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury. J Neurosci 2005, 25(32):7317-23. 10.1523/JNEUROSCI.1526-05.2005, 16093381.
4. Suzuki R, Dickenson A. Spinal and supraspinal contributions to central sensitization in peripheral neuropathy. Neurosignals 2005, 14(4):175-81. 10.1159/000087656, 16215300.
5. Nichols DS, Thorn BE. Stimulation-produced analgesia and its cross-tolerance between dorsal and ventral PAG loci. Pain 1990, 41(3):347-52. 10.1016/0304-3959(90)90011-2, 2388771.
6. Peng YB, Wu J, Willis WD, Kenshalo DR. GABA(A) and 5-HT(3) receptors are involved in dorsal root reflexes: possible role in periaqueductal gray descending inhibition. J Neurophysiol 2001, 86(1):49-58.
7. Zhao ZQ, Chiechio S, Sun YG, Zhang KH, Zhao CS, Scott M, Johnson RL, Deneris ES, Renner KJ, Gereau R, Chen ZF. Mice lacking central serotonergic neurons show enhanced inflammatory pain and an impaired analgesic response to antidepressant drugs. J Neurosci 2007, 27(22):6045-53. 10.1523/JNEUROSCI.1623-07.2007, 17537976.
8. Berrocoso E, De Benito MD, Mico JA. Role of serotonin 5-HT1A and opioid receptors in the antiallodynic effect of tramadol in the chronic constriction injury model of neuropathic pain in rats. Psychopharmacology (Berl) 2007, 193(1):97-105. 10.1007/s00213-007-0761-8, 17393145.
9. Griffin RS, Mills CD, Costigan M, Woolf CJ. Exploiting microarrays to reveal differential gene expression in the nervous system. Genome Biol 2003, 4(2):105. 10.1186/gb-2003-4-2-105, 151293, 12620110.
10. Woolf CJ, Costigan M. Transcriptional and posttranslational plasticity and the generation of inflammatory pain. Proc Natl Acad Sci USA 1999, 96(14):7723-30. 10.1073/pnas.96.14.7723, 33609, 10393888.
11. Tegeder I, Costigan M, Griffin RS, Abele A, Belfer I, Schmidt H, Ehnert C, Nejim J, Marian C, Scholz J, Wu T, Allchorne A, Diatchenko L, Binshtok AM, Goldman D, Adolph J, Sama S, Atlas SJ, Carlezon WA, Parsegian A, Lotsch J, Fillingim RB, Maixner W, Geisslinger G, Max MB, Woolf CJ. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. Nat Med 2006, 12(11):1269-1277. 10.1038/nm1490, 17057711.
12. Walther DJ, Peter JU, Bashammakh S, Hortnagl H, Voits M, Fink H, Bader M. Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science 2003, 299(5603):76. 10.1126/science.1078197, 12511643.
13. Wilson SG, Chesler EJ, Hain H, Rankin AJ, Schwarz JZ, Call SB, Murray MR, West EE, Teuscher C, Rodriguez-Zas S, Belknap JK, Mogil JS. Identification of quantitative trait loci for chemical/inflammatory nociception in mice. Pain 2002, 96(3):385-91. 10.1016/S0304-3959(01)00489-4, 11973013.
14. Suzuki R, Rygh LJ, Dickenson AH. Bad news from the brain: descending 5-HT pathways that control spinal pain processing. Trends Pharmacol Sci 2004, 25(12):613-7. 10.1016/j.tips.2004.10.002, 15530638.
15. Mhyre TR, Chesler EJ, Thiruchelvam M, Lungu C, Cory-Slechta DA, Fry JD, Richfield EK. Heritability, correlations and in silico mapping of locomotor behavior and neurochemistry in inbred strains of mice. Genes Brain Behav 2005, 4(4):209-28.
16. Devoino LB, Al'perina EL, Podgornaya EK, Polyakov OV, Idova GV, Il'yuchenok RY. Brain content of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid and immune response in aggressive C57bl/6J mice. Bull Exp Biol Med 2000, 130(10):954-6. 10.1023/A:1002853521450, 11177291.
17. Harvey RJ, Depner UB, Wassle H, Ahmadi S, Heindl C, Reinold H, Smart TG, Harvey K, Schutz B, Abo-Salem OM, Zimmer A, Poisbeau P, Welzl H, Wolfer DP, Betz H, Zeilhofer HU, Muller U. GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization. Science 2004, 304(5672):884-7. 10.1126/science.1094925, 15131310.
18. Hosl K, Reinold H, Harvey RJ, Muller U, Narumiya S, Zeilhofer HU. Spinal prostaglandin E receptors of the EP2 subtype and the glycine receptor alpha3 subunit, which mediate central inflammatory hyperalgesia, do not contribute to pain after peripheral nerve injury or formalin injection. Pain 2006, 126(1-3):46-53. 10.1016/j.pain.2006.06.011, 16846696.
19. Moore KA, Kohno T, Karchewski LA, Scholz J, Baba H, Woolf CJ. Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord. J Neurosci 2002, 22(15):6724-31.
20. Hains BC, Everhart AW, Fullwood SD, Hulsebosch CE. Changes in serotonin, serotonin transporter expression and serotonin denervation supersensitivity: involvement in chronic central pain after spinal hemisection in the rat. Exp Neurol 2002, 175(2):347-62. 10.1006/exnr.2002.7892, 12061865.
21. Alhaider AA, Lei SZ, Wilcox GL. Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA. J Neurosci 1991, 11(7):1881-8.
22. Suzuki R, Morcuende S, Webber M, Hunt SP, Dickenson AH. Superficial NK1-expressing neurons control spinal excitability through activation of descending pathways. Nat Neurosci 2002, 5(12):1319-26. 10.1038/nn966, 12402039.
23. Suzuki R, Rahman W, Rygh LJ, Webber M, Hunt SP, Dickenson AH. Spinal-supraspinal serotonergic circuits regulating neuropathic pain and its treatment with gabapentin. Pain 2005, 117(3):292-303. 10.1016/j.pain.2005.06.015, 16150546.
24. Dubuisson D, Dennis SG. The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. Pain 1977, 4(2):161-74.
25. Tjolsen A, Berge OG, Hunskaar S, Rosland JH, Hole K. The formalin test: an evaluation of the method. Pain 1992, 51(1):5-17. 10.1016/0304-3959(92)90003-T, 1454405.
26. Decosterd I, Woolf CJ. Spared nerve injury: an animal model of persistent peripheral neuropathic pain. Pain 2000, 87(2):149-58. 10.1016/S0304-3959(00)00276-1, 10924808.
27. Bourquin AF, Suveges M, Pertin M, Gilliard N, Sardy S, Davison AC, Spahn DR, Decosterd I. Assessment and analysis of mechanical allodynia-like behavior induced by spared nerve injury (SNI) in the mouse. Pain 2006, 122(1-2):14. e1-14, 10.1016/j.pain.2005.10.036, 16542774.
28. Mogil JS, Wilson SG, Bon K, Lee SE, Chung K, Raber P, Pieper JO, Hain HS, Belknap JK, Hubert L, Elmer GI, Chung JM, Devor M. Heritability of nociception II. 'Types' of nociception revealed by genetic correlation analysis. Pain 1999, 80(1-2):83-93. 10.1016/S0304-3959(98)00196-1, 10204720.
29. Mogil JS, Wilson SG, Bon K, Lee SE, Chung K, Raber P, Pieper JO, Hain HS, Belknap JK, Hubert L, Elmer GI, Chung JM, Devor M. Heritability of nociception I: responses of 11 inbred mouse strains on 12 measures of nociception. Pain 1999, 80(1-2):67-82. 10.1016/S0304-3959(98)00197-3, 10204719.
30. Bon K, Wilson SG, Mogil JS, Roberts WJ. Genetic evidence for the correlation of deep dorsal horn Fos protein immunoreactivity with tonic formalin pain behavior. J Pain 2002, 3(3):181-9. 10.1054/jpai.2002.123710, 14622771.
31. Hoover-Plow JL, Gong Y, Shchurin A, Busuttil SJ, Schneeman TA, Hart E. Strain and model dependent differences in inflammatory cell recruitment in mice. Inflamm Res 2008, 57(10):457-63. 10.1007/s00011-008-7062-5, 18827970.
32. Lopez-Garcia JA, King AE. Pre- and post-synaptic actions of 5-hydroxytryptamine in the rat lumbar dorsal horn in vitro: implications for somatosensory transmission. Eur J Neurosci 1996, 8(10):2188-97. 10.1111/j.1460-9568.1996.tb00740.x, 8921310.
33. Linhart O, Obreja O, Kress M. The inflammatory mediators serotonin, prostaglandin E2 and bradykinin evoke calcium influx in rat sensory neurons. Neuroscience 2003, 118(1):69-74. 10.1016/S0306-4522(02)00960-0, 12676138.
34. Okamoto K, Imbe H, Morikawa Y, Itoh M, Sekimoto M, Nemoto K, Senba E. 5-HT2A receptor subtype in the peripheral branch of sensory fibers is involved in the potentiation of inflammatory pain in rats. Pain 2002, 99(1-2):133-43. 10.1016/S0304-3959(02)00070-2, 12237191.
35. Mamet J, Baron A, Lazdunski M, Voilley N. Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels. J Neurosci 2002, 22(24):10662-70.
36. Tokunaga A, Saika M, Senba E. 5-HT2A receptor subtype is involved in the thermal hyperalgesic mechanism of serotonin in the periphery. Pain 1998, 76(3):349-55. 10.1016/S0304-3959(98)00066-9, 9718253.
37. Gold MS, Reichling DB, Shuster MJ, Levine JD. Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors. Proc Natl Acad Sci USA 1996, 93(3):1108-12. 10.1073/pnas.93.3.1108, 40039, 8577723.
38. Braz JM, Basbaum AI. Genetically expressed transneuronal tracer reveals direct and indirect serotonergic descending control circuits. J Comp Neurol 2008, 507(6):1990-2003. 10.1002/cne.21665, 18273889.
39. Braz JM, Enquist LW, Basbaum AI. Inputs to serotonergic neurons revealed by conditional viral transneuronal tracing. J Comp Neurol 2009, 514(2):145-60. 10.1002/cne.22003, 2696271, 19274668.
40. Tapocik JD, Letwin N, Mayo CL, Frank B, Luu T, Achinike O, House C, Williams R, Elmer GI, Lee NH. Identification of candidate genes and gene networks specifically associated with analgesic tolerance to morphine. J Neurosci 2009, 29(16):5295-307. 10.1523/JNEUROSCI.4020-08.2009, 2933065, 19386926.
41. Cervo L, Canetta A, Calcagno E, Burbassi S, Sacchetti G, Caccia S, Fracasso C, Albani D, Forloni G, Invernizzi RW. Genotype-dependent activity of tryptophan hydroxylase-2 determines the response to citalopram in a mouse model of depression. J Neurosci 2005, 25(36):8165-72. 10.1523/JNEUROSCI.1816-05.2005, 16148224.
42. Zhang X, Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG. Tryptophan hydroxylase-2 controls brain serotonin synthesis. Science 2004, 305(5681):217. 10.1126/science.1097540, 15247473.
43. Tenner K, Qadri F, Bert B, Voigt JP, Bader M. The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains. Neurosci Lett 2008, 431(1):21-5. 10.1016/j.neulet.2007.11.012, 18082956.
44. Carneiro AM, Airey DC, Thompson B, Zhu CB, Lu L, Chesler EJ, Erikson KM, Blakely RD. Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes. Proc Natl Acad Sci USA 2009, 106(6):2047-52. 10.1073/pnas.0809449106, 2632716, 19179283.
45. Berrocoso E, Rojas-Corrales MO, Mico JA. Differential role of 5-HT1A and 5-HT1B receptors on the antinociceptive and antidepressant effect of tramadol in mice. Psychopharmacology (Berl) 2006, 188(1):111-8. 10.1007/s00213-006-0464-6, 16832657.
46. Suzuki R, Rahman W, Hunt SP, Dickenson AH. Descending facilitatory control of mechanically evoked responses is enhanced in deep dorsal horn neurones following peripheral nerve injury. Brain Res 2004, 1019(1-2):68-76. 10.1016/j.brainres.2004.05.108, 15306240.
47. Xiao DQ, Zhu JX, Tang JS, Jia H. 5-hydroxytryptamine 1A (5-HT1A) but not 5-HT3 receptor is involved in mediating the nucleus submedius 5-HT-evoked antinociception in the rat. Brain Res 2005, 1046(1-2):38-44. 10.1016/j.brainres.2005.03.028, 15869749.
48. Lanoir J, Hilaire G, Seif I. Reduced density of functional 5-HT1A receptors in the brain, medulla and spinal cord of monoamine oxidase-A knockout mouse neonates. J Comp Neurol 2006, 495(5):607-23. 10.1002/cne.20916, 16498683.